Rank | Gene Set | Z-score |
---|---|---|
1 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 6.09177507 |
2 | synaptic vesicle maturation (GO:0016188) | 5.61874556 |
3 | vocalization behavior (GO:0071625) | 5.58643138 |
4 | locomotory exploration behavior (GO:0035641) | 5.58420981 |
5 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 5.57319123 |
6 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 5.57209362 |
7 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 5.52492613 |
8 | layer formation in cerebral cortex (GO:0021819) | 5.14088670 |
9 | regulation of glutamate receptor signaling pathway (GO:1900449) | 5.08683409 |
10 | synaptic vesicle exocytosis (GO:0016079) | 4.99675619 |
11 | dendritic spine morphogenesis (GO:0060997) | 4.97738646 |
12 | protein localization to synapse (GO:0035418) | 4.88556399 |
13 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 4.77766149 |
14 | neuron cell-cell adhesion (GO:0007158) | 4.77178585 |
15 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 4.67852438 |
16 | glutamate secretion (GO:0014047) | 4.66480016 |
17 | exploration behavior (GO:0035640) | 4.57501237 |
18 | regulation of synaptic vesicle exocytosis (GO:2000300) | 4.40821700 |
19 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 4.36834549 |
20 | regulation of neuronal synaptic plasticity (GO:0048168) | 4.35591326 |
21 | positive regulation of synapse maturation (GO:0090129) | 4.30050449 |
22 | synaptic transmission, glutamatergic (GO:0035249) | 4.22290465 |
23 | glutamate receptor signaling pathway (GO:0007215) | 4.17854298 |
24 | neurotransmitter secretion (GO:0007269) | 4.16113015 |
25 | neuron recognition (GO:0008038) | 4.15441862 |
26 | regulation of synapse structural plasticity (GO:0051823) | 4.08465042 |
27 | cell migration in hindbrain (GO:0021535) | 4.07508599 |
28 | axonal fasciculation (GO:0007413) | 4.05678908 |
29 | establishment of mitochondrion localization (GO:0051654) | 3.99794851 |
30 | proline transport (GO:0015824) | 3.97176436 |
31 | neuron-neuron synaptic transmission (GO:0007270) | 3.88572343 |
32 | regulation of synaptic vesicle transport (GO:1902803) | 3.88242564 |
33 | long-term memory (GO:0007616) | 3.83203358 |
34 | neuronal action potential propagation (GO:0019227) | 3.81844139 |
35 | cerebellar granule cell differentiation (GO:0021707) | 3.78605473 |
36 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 3.75719852 |
37 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.74967676 |
38 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 3.74881542 |
39 | regulation of dendritic spine morphogenesis (GO:0061001) | 3.73999676 |
40 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 3.73082166 |
41 | establishment of mitochondrion localization, microtubule-mediated (GO:0034643) | 3.72904361 |
42 | mitochondrion transport along microtubule (GO:0047497) | 3.72904361 |
43 | positive regulation of membrane potential (GO:0045838) | 3.69420529 |
44 | synaptic vesicle endocytosis (GO:0048488) | 3.64669883 |
45 | presynaptic membrane assembly (GO:0097105) | 3.62282619 |
46 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 3.61173861 |
47 | gamma-aminobutyric acid transport (GO:0015812) | 3.60577145 |
48 | central nervous system projection neuron axonogenesis (GO:0021952) | 3.58860310 |
49 | negative regulation of microtubule polymerization (GO:0031115) | 3.55915524 |
50 | transmission of nerve impulse (GO:0019226) | 3.54806317 |
51 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 3.53574692 |
52 | neuromuscular process controlling balance (GO:0050885) | 3.53058239 |
53 | dendritic spine organization (GO:0097061) | 3.50411686 |
54 | presynaptic membrane organization (GO:0097090) | 3.49404313 |
55 | regulation of postsynaptic membrane potential (GO:0060078) | 3.48978547 |
56 | innervation (GO:0060384) | 3.45914220 |
57 | dendrite morphogenesis (GO:0048813) | 3.45772695 |
58 | postsynaptic membrane organization (GO:0001941) | 3.45244239 |
59 | auditory behavior (GO:0031223) | 3.42307240 |
60 | cerebellar Purkinje cell differentiation (GO:0021702) | 3.40666816 |
61 | regulation of synaptic plasticity (GO:0048167) | 3.39358918 |
62 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 3.36671711 |
63 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 3.33791880 |
64 | behavioral fear response (GO:0001662) | 3.33414924 |
65 | behavioral defense response (GO:0002209) | 3.33414924 |
66 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 3.32848167 |
67 | central nervous system myelination (GO:0022010) | 3.32646100 |
68 | axon ensheathment in central nervous system (GO:0032291) | 3.32646100 |
69 | neurotransmitter transport (GO:0006836) | 3.31703650 |
70 | positive regulation of dendritic spine development (GO:0060999) | 3.31317478 |
71 | prepulse inhibition (GO:0060134) | 3.27818657 |
72 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.25405043 |
73 | regulation of synapse maturation (GO:0090128) | 3.22351547 |
74 | neuronal ion channel clustering (GO:0045161) | 3.18362076 |
75 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 3.17877417 |
76 | cellular potassium ion homeostasis (GO:0030007) | 3.16566953 |
77 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 3.16304087 |
78 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 3.14373860 |
79 | pyrimidine nucleobase catabolic process (GO:0006208) | 3.11273537 |
80 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 3.11117962 |
81 | establishment of nucleus localization (GO:0040023) | 3.10882239 |
82 | activation of protein kinase A activity (GO:0034199) | 3.08553738 |
83 | response to auditory stimulus (GO:0010996) | 3.08060386 |
84 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.07368042 |
85 | fear response (GO:0042596) | 3.06619037 |
86 | positive regulation of synaptic transmission, glutamatergic (GO:0051968) | 3.06005441 |
87 | amino acid import (GO:0043090) | 3.04443488 |
88 | response to histamine (GO:0034776) | 3.04133232 |
89 | membrane hyperpolarization (GO:0060081) | 3.03140793 |
90 | learning (GO:0007612) | 3.02435271 |
91 | regulation of dendritic spine development (GO:0060998) | 3.02087412 |
92 | cell-cell junction maintenance (GO:0045217) | 3.01312648 |
93 | regulation of neurotransmitter levels (GO:0001505) | 3.00537343 |
94 | regulation of neurotransmitter secretion (GO:0046928) | 2.99509484 |
95 | cerebellar Purkinje cell layer development (GO:0021680) | 2.99437026 |
96 | synapse assembly (GO:0007416) | 2.98012146 |
97 | sodium ion export (GO:0071436) | 2.96230173 |
98 | positive regulation of neurotransmitter secretion (GO:0001956) | 2.95299323 |
99 | membrane depolarization (GO:0051899) | 2.94990147 |
100 | regulation of vesicle fusion (GO:0031338) | 2.94897906 |
101 | neuromuscular process controlling posture (GO:0050884) | 2.94501622 |
102 | long-term synaptic potentiation (GO:0060291) | 2.93275551 |
103 | neuromuscular process (GO:0050905) | 2.92694464 |
104 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 2.92286855 |
105 | regulation of respiratory system process (GO:0044065) | 2.92121869 |
106 | social behavior (GO:0035176) | 2.91752732 |
107 | intraspecies interaction between organisms (GO:0051703) | 2.91752732 |
108 | cell communication by electrical coupling (GO:0010644) | 2.90168019 |
109 | L-amino acid import (GO:0043092) | 2.87657490 |
110 | semaphorin-plexin signaling pathway (GO:0071526) | 2.86652505 |
111 | cerebellum development (GO:0021549) | 2.86300786 |
112 | potassium ion homeostasis (GO:0055075) | 2.86049728 |
113 | positive regulation of neurotransmitter transport (GO:0051590) | 2.85726732 |
114 | membrane depolarization during action potential (GO:0086010) | 2.85481667 |
115 | synapse organization (GO:0050808) | 2.84929909 |
116 | apical protein localization (GO:0045176) | 2.84182326 |
117 | convergent extension (GO:0060026) | 2.82419264 |
118 | positive regulation of synapse assembly (GO:0051965) | 2.81337532 |
119 | dopamine receptor signaling pathway (GO:0007212) | 2.80694353 |
120 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 2.80670435 |
121 | positive regulation of dendrite development (GO:1900006) | 2.76435390 |
122 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 2.74792023 |
123 | negative regulation of catenin import into nucleus (GO:0035414) | 2.70833884 |
124 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 2.69516738 |
125 | axon extension (GO:0048675) | 2.69456015 |
126 | negative regulation of dendrite morphogenesis (GO:0050774) | 2.68459268 |
127 | mating behavior (GO:0007617) | 2.68130191 |
128 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 2.65935514 |
129 | regulation of dendrite morphogenesis (GO:0048814) | 2.63012597 |
130 | positive regulation of dendrite morphogenesis (GO:0050775) | 2.58071980 |
131 | regulation of ARF protein signal transduction (GO:0032012) | 2.58055819 |
132 | protein retention in ER lumen (GO:0006621) | 2.51029173 |
133 | camera-type eye morphogenesis (GO:0048593) | 2.50894306 |
134 | Wnt signaling pathway, planar cell polarity pathway (GO:0060071) | 2.50098962 |
135 | spinal cord development (GO:0021510) | 2.46892257 |
136 | cellular sodium ion homeostasis (GO:0006883) | 2.46050088 |
137 | regulation of axon extension involved in axon guidance (GO:0048841) | 2.44779698 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 6.62262806 |
2 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 3.07617366 |
3 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.95287641 |
4 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.90720451 |
5 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.82975247 |
6 | * RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.82804210 |
7 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.82585923 |
8 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.74595501 |
9 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.69100668 |
10 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.68023475 |
11 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.67657910 |
12 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.67657910 |
13 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.67614601 |
14 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 2.67594756 |
15 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.64533579 |
16 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.55990003 |
17 | * REST_18959480_ChIP-ChIP_MESCs_Mouse | 2.43906444 |
18 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.41428273 |
19 | * CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.35361590 |
20 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.35096905 |
21 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.34514814 |
22 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.25646945 |
23 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.23206753 |
24 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.22771849 |
25 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.22722328 |
26 | * MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.22579305 |
27 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.22257348 |
28 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.16731704 |
29 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.11149421 |
30 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 2.10422290 |
31 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 2.07856143 |
32 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 2.02038780 |
33 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.95505749 |
34 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.94292628 |
35 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.93965493 |
36 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.73848003 |
37 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.63042639 |
38 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.61077501 |
39 | * RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.60948243 |
40 | * RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.57373929 |
41 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.56755226 |
42 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.56240711 |
43 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.56208802 |
44 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.54801011 |
45 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.54546322 |
46 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.49709156 |
47 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.48691599 |
48 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.47023056 |
49 | KDM2B_26808549_Chip-Seq_K562_Human | 1.43738731 |
50 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.43716322 |
51 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.42408468 |
52 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.40850843 |
53 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.40399726 |
54 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.39696898 |
55 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.38445222 |
56 | * KDM2B_26808549_Chip-Seq_DND41_Human | 1.35743916 |
57 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.34732180 |
58 | * CREB1_26743006_Chip-Seq_LNCaP_Human | 1.33551395 |
59 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.32821763 |
60 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.31545284 |
61 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.29585243 |
62 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.28740184 |
63 | * UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.28681963 |
64 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.27793501 |
65 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.25309545 |
66 | AR_19668381_ChIP-Seq_PC3_Human | 1.23858765 |
67 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.20077759 |
68 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.20046429 |
69 | P68_20966046_ChIP-Seq_HELA_Human | 1.19681244 |
70 | * KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.19669187 |
71 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.19498568 |
72 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.18437405 |
73 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.17365711 |
74 | POU5F1_16518401_ChIP-PET_MESCs_Mouse | 1.15736213 |
75 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.15058840 |
76 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.14268342 |
77 | * MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 1.13565545 |
78 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.11135203 |
79 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.10743772 |
80 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.09863956 |
81 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.08989795 |
82 | * WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.08732916 |
83 | SOX3_22085726_ChIP-Seq_NPCs_Mouse | 1.08652340 |
84 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 1.07469066 |
85 | SETDB1_19884255_ChIP-Seq_MESCs_Mouse | 1.06625856 |
86 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.06301978 |
87 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.05926025 |
88 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.05615070 |
89 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.04494169 |
90 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.04200516 |
91 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.03801216 |
92 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.03663947 |
93 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.02387595 |
94 | * DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.02207074 |
95 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.02004551 |
96 | * CTCF_27219007_Chip-Seq_Bcells_Human | 1.00901946 |
97 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.00729758 |
98 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.00115349 |
99 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.99872054 |
100 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.98933141 |
101 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 0.97674533 |
102 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.96748231 |
103 | * CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.95301860 |
104 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.95272395 |
105 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.94793243 |
106 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.92661796 |
107 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.92631757 |
108 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.92631757 |
109 | * SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.92566215 |
110 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 0.92492183 |
111 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.92355506 |
112 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 0.91416610 |
113 | STAT3_23295773_ChIP-Seq_U87_Human | 0.91264357 |
114 | RUNX1_26923725_Chip-Seq_HPCs_Mouse | 0.89699444 |
115 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 0.89542607 |
116 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.89099379 |
117 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 0.88860465 |
118 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.88520506 |
119 | * SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.88140176 |
120 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 0.87831251 |
121 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.87817010 |
122 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.87782756 |
123 | * KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.87242829 |
124 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.86953573 |
125 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.86893908 |
126 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 0.86321984 |
127 | P300_19829295_ChIP-Seq_ESCs_Human | 0.86098029 |
128 | * KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.85748850 |
129 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 0.85202179 |
130 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 0.84999184 |
131 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 0.83553006 |
132 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.83431733 |
133 | TFAP2A_17053090_ChIP-ChIP_MCF-7_Human | 0.82938140 |
134 | AR_25329375_ChIP-Seq_VCAP_Human | 0.82377928 |
135 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 0.81883975 |
136 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.81881779 |
137 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.81664130 |
138 | NANOG_18347094_ChIP-ChIP_MESCs_Mouse | 0.80661932 |
139 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 0.80626429 |
140 | FUS_26573619_Chip-Seq_HEK293_Human | 0.80587049 |
141 | POU5F1_18347094_ChIP-ChIP_MESCs_Mouse | 0.80316575 |
142 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.79904698 |
143 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.79820508 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 6.29120388 |
2 | MP0003880_abnormal_central_pattern | 4.40344291 |
3 | MP0003635_abnormal_synaptic_transmissio | 3.94892631 |
4 | MP0004270_analgesia | 3.44968733 |
5 | MP0002063_abnormal_learning/memory/cond | 3.23910560 |
6 | MP0009745_abnormal_behavioral_response | 3.06390740 |
7 | MP0005423_abnormal_somatic_nervous | 2.98160927 |
8 | MP0002064_seizures | 2.78432367 |
9 | MP0001968_abnormal_touch/_nociception | 2.65256643 |
10 | MP0009046_muscle_twitch | 2.62555515 |
11 | MP0002572_abnormal_emotion/affect_behav | 2.62512984 |
12 | MP0000566_synostosis | 2.59290120 |
13 | MP0002734_abnormal_mechanical_nocicepti | 2.40795208 |
14 | MP0000778_abnormal_nervous_system | 2.36512095 |
15 | MP0002822_catalepsy | 2.33532774 |
16 | MP0001486_abnormal_startle_reflex | 2.32068306 |
17 | MP0002272_abnormal_nervous_system | 2.21844150 |
18 | MP0002184_abnormal_innervation | 2.06670246 |
19 | MP0004858_abnormal_nervous_system | 2.00219645 |
20 | MP0002733_abnormal_thermal_nociception | 1.98338404 |
21 | MP0002735_abnormal_chemical_nociception | 1.97837489 |
22 | MP0003787_abnormal_imprinting | 1.95157144 |
23 | MP0002736_abnormal_nociception_after | 1.92090496 |
24 | MP0001440_abnormal_grooming_behavior | 1.90234378 |
25 | MP0003122_maternal_imprinting | 1.89586009 |
26 | MP0004811_abnormal_neuron_physiology | 1.86523871 |
27 | MP0010030_abnormal_orbit_morphology | 1.85499180 |
28 | MP0003705_abnormal_hypodermis_morpholog | 1.85399346 |
29 | MP0001501_abnormal_sleep_pattern | 1.84542494 |
30 | MP0002249_abnormal_larynx_morphology | 1.84243209 |
31 | MP0002557_abnormal_social/conspecific_i | 1.79552716 |
32 | MP0001970_abnormal_pain_threshold | 1.77027840 |
33 | MP0002067_abnormal_sensory_capabilities | 1.76059413 |
34 | MP0000955_abnormal_spinal_cord | 1.75875181 |
35 | MP0005386_behavior/neurological_phenoty | 1.63641446 |
36 | MP0004924_abnormal_behavior | 1.63641446 |
37 | MP0006276_abnormal_autonomic_nervous | 1.62278208 |
38 | MP0000579_abnormal_nail_morphology | 1.59043733 |
39 | MP0008569_lethality_at_weaning | 1.54880648 |
40 | MP0000569_abnormal_digit_pigmentation | 1.54026718 |
41 | MP0004885_abnormal_endolymph | 1.51587655 |
42 | MP0003283_abnormal_digestive_organ | 1.50986759 |
43 | MP0001529_abnormal_vocalization | 1.49796587 |
44 | MP0002882_abnormal_neuron_morphology | 1.48763291 |
45 | MP0003123_paternal_imprinting | 1.43086455 |
46 | MP0002152_abnormal_brain_morphology | 1.41726211 |
47 | MP0001299_abnormal_eye_distance/ | 1.40817167 |
48 | MP0002909_abnormal_adrenal_gland | 1.38859037 |
49 | MP0009780_abnormal_chondrocyte_physiolo | 1.35671880 |
50 | MP0002066_abnormal_motor_capabilities/c | 1.35303843 |
51 | MP0005394_taste/olfaction_phenotype | 1.34419623 |
52 | MP0005499_abnormal_olfactory_system | 1.34419623 |
53 | MP0003121_genomic_imprinting | 1.32216854 |
54 | MP0005645_abnormal_hypothalamus_physiol | 1.30449197 |
55 | MP0002653_abnormal_ependyma_morphology | 1.30067159 |
56 | MP0003942_abnormal_urinary_system | 1.29168289 |
57 | MP0003329_amyloid_beta_deposits | 1.28974893 |
58 | MP0001346_abnormal_lacrimal_gland | 1.25683684 |
59 | MP0003861_abnormal_nervous_system | 1.22850970 |
60 | MP0001984_abnormal_olfaction | 1.22829457 |
61 | MP0001849_ear_inflammation | 1.17944236 |
62 | MP0002089_abnormal_postnatal_growth/wei | 1.15913594 |
63 | MP0003879_abnormal_hair_cell | 1.15578806 |
64 | MP0000049_abnormal_middle_ear | 1.14474088 |
65 | MP0004142_abnormal_muscle_tone | 1.14118757 |
66 | MP0000631_abnormal_neuroendocrine_gland | 1.12927749 |
67 | MP0003385_abnormal_body_wall | 1.12077770 |
68 | MP0001348_abnormal_lacrimal_gland | 1.09945614 |
69 | MP0005409_darkened_coat_color | 1.06796013 |
70 | MP0003119_abnormal_digestive_system | 1.04788109 |
71 | MP0000537_abnormal_urethra_morphology | 1.04315985 |
72 | MP0005646_abnormal_pituitary_gland | 1.02572275 |
73 | MP0008961_abnormal_basal_metabolism | 1.02062145 |
74 | MP0002116_abnormal_craniofacial_bone | 1.00796080 |
75 | MP0006292_abnormal_olfactory_placode | 1.00070901 |
76 | MP0001502_abnormal_circadian_rhythm | 0.97364240 |
77 | MP0005257_abnormal_intraocular_pressure | 0.95835037 |
78 | MP0002697_abnormal_eye_size | 0.95509317 |
79 | MP0004133_heterotaxia | 0.93849519 |
80 | MP0001188_hyperpigmentation | 0.93310171 |
81 | MP0000428_abnormal_craniofacial_morphol | 0.92770017 |
82 | MP0003633_abnormal_nervous_system | 0.92622184 |
83 | MP0005076_abnormal_cell_differentiation | 0.92176659 |
84 | MP0009672_abnormal_birth_weight | 0.90637520 |
85 | MP0002752_abnormal_somatic_nervous | 0.89901007 |
86 | MP0008872_abnormal_physiological_respon | 0.89519453 |
87 | MP0004145_abnormal_muscle_electrophysio | 0.89382623 |
88 | MP0005187_abnormal_penis_morphology | 0.89200953 |
89 | MP0003890_abnormal_embryonic-extraembry | 0.89154744 |
90 | MP0001905_abnormal_dopamine_level | 0.88981140 |
91 | MP0002069_abnormal_eating/drinking_beha | 0.88493763 |
92 | MP0004233_abnormal_muscle_weight | 0.88226428 |
93 | MP0003937_abnormal_limbs/digits/tail_de | 0.87163498 |
94 | MP0003115_abnormal_respiratory_system | 0.85517828 |
95 | MP0000462_abnormal_digestive_system | 0.85202172 |
96 | MP0003631_nervous_system_phenotype | 0.85030085 |
97 | MP0003690_abnormal_glial_cell | 0.84287064 |
98 | MP0000762_abnormal_tongue_morphology | 0.81621539 |
99 | MP0005623_abnormal_meninges_morphology | 0.80032700 |
100 | MP0006072_abnormal_retinal_apoptosis | 0.80016543 |
101 | MP0002233_abnormal_nose_morphology | 0.79943308 |
102 | MP0000920_abnormal_myelination | 0.79806906 |
103 | MP0003938_abnormal_ear_development | 0.79086166 |
104 | MP0004742_abnormal_vestibular_system | 0.76688435 |
105 | MP0005377_hearing/vestibular/ear_phenot | 0.75921767 |
106 | MP0003878_abnormal_ear_physiology | 0.75921767 |
107 | MP0001485_abnormal_pinna_reflex | 0.75505933 |
108 | MP0001963_abnormal_hearing_physiology | 0.75204160 |
109 | MP0003755_abnormal_palate_morphology | 0.74095285 |
110 | MP0002751_abnormal_autonomic_nervous | 0.73218784 |
111 | MP0003632_abnormal_nervous_system | 0.72079148 |
112 | MP0001943_abnormal_respiration | 0.71993282 |
113 | MP0008789_abnormal_olfactory_epithelium | 0.71159723 |
114 | MP0001177_atelectasis | 0.69997280 |
115 | MP0002234_abnormal_pharynx_morphology | 0.69887046 |
116 | MP0010769_abnormal_survival | 0.69662194 |
117 | MP0002081_perinatal_lethality | 0.69628635 |
118 | MP0002229_neurodegeneration | 0.68947934 |
119 | MP0000751_myopathy | 0.68070420 |
120 | MP0002082_postnatal_lethality | 0.67145992 |
121 | MP0010770_preweaning_lethality | 0.67145992 |
122 | MP0010768_mortality/aging | 0.66548045 |
123 | MP0003137_abnormal_impulse_conducting | 0.66225865 |
124 | MP0000534_abnormal_ureter_morphology | 0.65393822 |
125 | MP0000026_abnormal_inner_ear | 0.65392448 |
126 | MP0010234_abnormal_vibrissa_follicle | 0.65019599 |
127 | MP0002102_abnormal_ear_morphology | 0.63703726 |
128 | MP0003634_abnormal_glial_cell | 0.63329554 |
129 | MP0004085_abnormal_heartbeat | 0.63003461 |
130 | MP0008877_abnormal_DNA_methylation | 0.61782139 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Focal motor seizures (HP:0011153) | 5.91928877 |
2 | Myokymia (HP:0002411) | 5.84978393 |
3 | Focal seizures (HP:0007359) | 4.81117415 |
4 | Visual hallucinations (HP:0002367) | 4.62875104 |
5 | Epileptic encephalopathy (HP:0200134) | 3.88417356 |
6 | Abnormality of the lower motor neuron (HP:0002366) | 3.56569527 |
7 | Febrile seizures (HP:0002373) | 3.53635522 |
8 | Atonic seizures (HP:0010819) | 3.53568596 |
9 | Progressive cerebellar ataxia (HP:0002073) | 3.50966897 |
10 | Absence seizures (HP:0002121) | 3.33562585 |
11 | Turricephaly (HP:0000262) | 3.30233975 |
12 | Broad-based gait (HP:0002136) | 3.24333333 |
13 | Generalized tonic-clonic seizures (HP:0002069) | 3.04000371 |
14 | Ankle clonus (HP:0011448) | 2.99611504 |
15 | Poor eye contact (HP:0000817) | 2.98931421 |
16 | Dialeptic seizures (HP:0011146) | 2.96670022 |
17 | Supranuclear gaze palsy (HP:0000605) | 2.94246981 |
18 | Action tremor (HP:0002345) | 2.91026832 |
19 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.90985200 |
20 | Amyotrophic lateral sclerosis (HP:0007354) | 2.89379811 |
21 | Amblyopia (HP:0000646) | 2.84729482 |
22 | Shallow orbits (HP:0000586) | 2.82688629 |
23 | Aplasia involving bones of the upper limbs (HP:0009823) | 2.82506994 |
24 | Aplasia of the phalanges of the hand (HP:0009802) | 2.82506994 |
25 | Aplasia involving bones of the extremities (HP:0009825) | 2.82506994 |
26 | Bronchomalacia (HP:0002780) | 2.79704187 |
27 | Depression (HP:0000716) | 2.71665735 |
28 | Drooling (HP:0002307) | 2.68993169 |
29 | Excessive salivation (HP:0003781) | 2.68993169 |
30 | Impaired social interactions (HP:0000735) | 2.68324964 |
31 | Abnormal social behavior (HP:0012433) | 2.68324964 |
32 | Annular pancreas (HP:0001734) | 2.68031282 |
33 | Neurofibrillary tangles (HP:0002185) | 2.65054730 |
34 | Genetic anticipation (HP:0003743) | 2.63079380 |
35 | Insomnia (HP:0100785) | 2.60789459 |
36 | Pointed chin (HP:0000307) | 2.60591753 |
37 | Hemiparesis (HP:0001269) | 2.60397733 |
38 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.57566403 |
39 | Impaired smooth pursuit (HP:0007772) | 2.56813693 |
40 | Mutism (HP:0002300) | 2.55940442 |
41 | Abnormality of the aortic arch (HP:0012303) | 2.53417674 |
42 | Dysdiadochokinesis (HP:0002075) | 2.52861887 |
43 | Urinary urgency (HP:0000012) | 2.51740371 |
44 | Vitreoretinal degeneration (HP:0000655) | 2.49984024 |
45 | Truncal ataxia (HP:0002078) | 2.49732981 |
46 | Gaze-evoked nystagmus (HP:0000640) | 2.48735786 |
47 | Abnormality of the labia minora (HP:0012880) | 2.33431657 |
48 | Hyperventilation (HP:0002883) | 2.27751289 |
49 | Abnormality of ocular smooth pursuit (HP:0000617) | 2.26635760 |
50 | Abnormal eating behavior (HP:0100738) | 2.26268358 |
51 | Dysmetria (HP:0001310) | 2.22945544 |
52 | Stereotypic behavior (HP:0000733) | 2.22880940 |
53 | Sleep apnea (HP:0010535) | 2.22348203 |
54 | Papilledema (HP:0001085) | 2.21755556 |
55 | Limb dystonia (HP:0002451) | 2.19744907 |
56 | Spastic gait (HP:0002064) | 2.16821248 |
57 | Abnormality of the astrocytes (HP:0100707) | 2.15363077 |
58 | Astrocytoma (HP:0009592) | 2.15363077 |
59 | Renal duplication (HP:0000075) | 2.15132430 |
60 | Hyperacusis (HP:0010780) | 2.14816391 |
61 | Ulnar bowing (HP:0003031) | 2.13745732 |
62 | Anxiety (HP:0000739) | 2.13058550 |
63 | Cerebral inclusion bodies (HP:0100314) | 2.12866618 |
64 | Insidious onset (HP:0003587) | 2.12744223 |
65 | Termporal pattern (HP:0011008) | 2.12744223 |
66 | Diplopia (HP:0000651) | 2.12190249 |
67 | Abnormality of binocular vision (HP:0011514) | 2.12190249 |
68 | Ankyloglossia (HP:0010296) | 2.10289692 |
69 | Abnormality of the corticospinal tract (HP:0002492) | 2.09878748 |
70 | Postural instability (HP:0002172) | 2.07606401 |
71 | Renovascular hypertension (HP:0100817) | 2.07198085 |
72 | Epileptiform EEG discharges (HP:0011182) | 2.06330154 |
73 | Obstructive sleep apnea (HP:0002870) | 2.05868519 |
74 | Peripheral hypomyelination (HP:0007182) | 2.05331550 |
75 | Megalencephaly (HP:0001355) | 2.02731796 |
76 | Inappropriate behavior (HP:0000719) | 2.02729001 |
77 | Coronal craniosynostosis (HP:0004440) | 2.02435970 |
78 | EEG with generalized epileptiform discharges (HP:0011198) | 2.01104169 |
79 | Bradykinesia (HP:0002067) | 2.00700171 |
80 | Absent speech (HP:0001344) | 2.00634838 |
81 | Cutaneous finger syndactyly (HP:0010554) | 1.97746937 |
82 | Trigonocephaly (HP:0000243) | 1.96667380 |
83 | Hemiplegia (HP:0002301) | 1.96605302 |
84 | Partial duplication of thumb phalanx (HP:0009944) | 1.95855507 |
85 | Cutaneous syndactyly (HP:0012725) | 1.93634425 |
86 | Morphological abnormality of the inner ear (HP:0011390) | 1.93259342 |
87 | Neonatal short-limb short stature (HP:0008921) | 1.92869060 |
88 | Thin ribs (HP:0000883) | 1.92620635 |
89 | Apathy (HP:0000741) | 1.92336128 |
90 | Hypsarrhythmia (HP:0002521) | 1.91753163 |
91 | Choanal stenosis (HP:0000452) | 1.91602487 |
92 | Progressive inability to walk (HP:0002505) | 1.90704330 |
93 | Partial duplication of the phalanx of hand (HP:0009999) | 1.90457242 |
94 | Elfin facies (HP:0004428) | 1.88218257 |
95 | Autism (HP:0000717) | 1.86982793 |
96 | Torticollis (HP:0000473) | 1.86338031 |
97 | Bowel diverticulosis (HP:0005222) | 1.85848128 |
98 | Sacral dimple (HP:0000960) | 1.85645591 |
99 | Arnold-Chiari malformation (HP:0002308) | 1.85105750 |
100 | Neoplasm of the heart (HP:0100544) | 1.85002838 |
101 | High anterior hairline (HP:0009890) | 1.84282825 |
102 | Ependymoma (HP:0002888) | 1.83751860 |
103 | Scanning speech (HP:0002168) | 1.83573799 |
104 | Dysmetric saccades (HP:0000641) | 1.81301398 |
105 | Broad face (HP:0000283) | 1.80001661 |
106 | Tracheomalacia (HP:0002779) | 1.79198990 |
107 | Polyphagia (HP:0002591) | 1.79128229 |
108 | Focal dystonia (HP:0004373) | 1.78308254 |
109 | Cerebral aneurysm (HP:0004944) | 1.77906435 |
110 | Alacrima (HP:0000522) | 1.77831545 |
111 | Increased nuchal translucency (HP:0010880) | 1.77585305 |
112 | Bladder diverticulum (HP:0000015) | 1.77387543 |
113 | Specific learning disability (HP:0001328) | 1.75811773 |
114 | Broad distal phalanx of finger (HP:0009836) | 1.75237753 |
115 | Agitation (HP:0000713) | 1.74133868 |
116 | Impaired vibratory sensation (HP:0002495) | 1.74043530 |
117 | Lower limb amyotrophy (HP:0007210) | 1.73791686 |
118 | Shoulder girdle muscle weakness (HP:0003547) | 1.73715599 |
119 | Obsessive-compulsive behavior (HP:0000722) | 1.72735472 |
120 | Hammertoe (HP:0001765) | 1.72009904 |
121 | Truncus arteriosus (HP:0001660) | 1.71904068 |
122 | Failure to thrive in infancy (HP:0001531) | 1.71427714 |
123 | Precocious puberty (HP:0000826) | 1.71371470 |
124 | Broad metatarsal (HP:0001783) | 1.71076172 |
125 | Distal upper limb amyotrophy (HP:0007149) | 1.71056530 |
126 | Upper limb amyotrophy (HP:0009129) | 1.71056530 |
127 | Hypoplasia of the brainstem (HP:0002365) | 1.71042336 |
128 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 1.71042336 |
129 | Status epilepticus (HP:0002133) | 1.71037283 |
130 | Gastroesophageal reflux (HP:0002020) | 1.69949225 |
131 | Lower limb muscle weakness (HP:0007340) | 1.69836116 |
132 | Overriding aorta (HP:0002623) | 1.69818060 |
133 | Akinesia (HP:0002304) | 1.69307341 |
134 | Aqueductal stenosis (HP:0002410) | 1.68695540 |
135 | Generalized hypotonia (HP:0001290) | 1.67545485 |
136 | Abnormality of cochlea (HP:0000375) | 1.67337699 |
137 | Flat cornea (HP:0007720) | 1.67218936 |
138 | Fetal akinesia sequence (HP:0001989) | 1.67100355 |
139 | Sporadic (HP:0003745) | 1.66099149 |
140 | Split foot (HP:0001839) | 1.66023123 |
141 | Incomplete penetrance (HP:0003829) | 1.65635640 |
142 | Morphological abnormality of the middle ear (HP:0008609) | 1.65540937 |
143 | Diminished motivation (HP:0000745) | 1.65238675 |
144 | Hepatoblastoma (HP:0002884) | 1.65110491 |
145 | Lymphangioma (HP:0100764) | 1.64054555 |
146 | Abnormality of the diencephalon (HP:0010662) | 1.63270404 |
147 | Intention tremor (HP:0002080) | 1.62969450 |
148 | Vertebral arch anomaly (HP:0008438) | 1.62641713 |
149 | Lower limb asymmetry (HP:0100559) | 1.62537588 |
150 | Hand muscle atrophy (HP:0009130) | 1.62378946 |
151 | Hypoventilation (HP:0002791) | 1.61879874 |
152 | Protruding tongue (HP:0010808) | 1.61256793 |
153 | Hyperthyroidism (HP:0000836) | 1.60173534 |
154 | Megalocornea (HP:0000485) | 1.59963132 |
155 | Long palpebral fissure (HP:0000637) | 1.59925744 |
156 | Abnormality of dentin (HP:0010299) | 1.59778842 |
157 | Biconcave vertebral bodies (HP:0004586) | 1.56329624 |
158 | Broad thumb (HP:0011304) | 1.53604855 |
159 | Germ cell neoplasia (HP:0100728) | 1.53426975 |
160 | Buphthalmos (HP:0000557) | 1.53129142 |
161 | Mild short stature (HP:0003502) | 1.52663472 |
162 | Bowel incontinence (HP:0002607) | 1.52512171 |
163 | Patellar dislocation (HP:0002999) | 1.52283998 |
Rank | Gene Set | Z-score |
---|---|---|
1 | NTRK3 | 4.25020470 |
2 | EPHA4 | 4.13614361 |
3 | MARK1 | 4.08931415 |
4 | MAP3K9 | 3.99168981 |
5 | TRIB3 | 3.30075858 |
6 | MAP3K4 | 2.98085239 |
7 | MINK1 | 2.56326562 |
8 | NTRK2 | 2.54174182 |
9 | PAK6 | 2.29435703 |
10 | DAPK2 | 2.28325810 |
11 | KSR1 | 2.21458533 |
12 | PNCK | 2.15642175 |
13 | EEF2K | 2.05187261 |
14 | SIK2 | 1.98998433 |
15 | TYRO3 | 1.98673577 |
16 | MAP2K7 | 1.98524204 |
17 | KSR2 | 1.84199452 |
18 | PRKD3 | 1.79081758 |
19 | DAPK1 | 1.72065645 |
20 | SIK1 | 1.65655115 |
21 | UHMK1 | 1.65292123 |
22 | MAP2K4 | 1.61887374 |
23 | LATS2 | 1.51423058 |
24 | PKN2 | 1.49753455 |
25 | CDK5 | 1.48982129 |
26 | CAMKK1 | 1.46753048 |
27 | NTRK1 | 1.45708402 |
28 | MAPK13 | 1.44993246 |
29 | SMG1 | 1.37514585 |
30 | ALK | 1.33020255 |
31 | ICK | 1.24456673 |
32 | PLK2 | 1.24042692 |
33 | FGFR4 | 1.21077840 |
34 | CASK | 1.18853495 |
35 | MAP3K12 | 1.17691916 |
36 | STK38 | 1.17301945 |
37 | TNIK | 1.15856677 |
38 | GRK5 | 1.15653331 |
39 | RIPK4 | 1.08527105 |
40 | PRKCG | 1.08136633 |
41 | CDK18 | 1.05637510 |
42 | PTK2 | 1.05392110 |
43 | CDK15 | 1.04223643 |
44 | CAMK1D | 0.96988941 |
45 | TAOK1 | 0.94883667 |
46 | FES | 0.94778232 |
47 | CDK14 | 0.94699211 |
48 | CDK11A | 0.93670033 |
49 | PHKG1 | 0.91520343 |
50 | PHKG2 | 0.91520343 |
51 | PRPF4B | 0.91334092 |
52 | CDK19 | 0.89743549 |
53 | NEK6 | 0.89252031 |
54 | STK11 | 0.87892851 |
55 | CSNK1G2 | 0.84898970 |
56 | MTOR | 0.84397263 |
57 | DYRK1A | 0.83417696 |
58 | NEK1 | 0.81505036 |
59 | FGR | 0.79069346 |
60 | RET | 0.76071237 |
61 | MARK2 | 0.73745492 |
62 | TESK1 | 0.73036546 |
63 | CAMK2A | 0.71041934 |
64 | DDR2 | 0.70818603 |
65 | MAP3K2 | 0.70167971 |
66 | RAF1 | 0.69646878 |
67 | EPHB2 | 0.68079978 |
68 | ARAF | 0.67760105 |
69 | PAK3 | 0.63162542 |
70 | WNK3 | 0.61492417 |
71 | CAMK2G | 0.60847734 |
72 | MAPK15 | 0.59993566 |
73 | PDGFRA | 0.59701144 |
74 | CDC42BPA | 0.59560110 |
75 | CAMK1 | 0.59443419 |
76 | CAMK1G | 0.58778621 |
77 | CAMK2B | 0.58690200 |
78 | EPHA2 | 0.58167849 |
79 | DYRK2 | 0.58112299 |
80 | BRAF | 0.57363243 |
81 | SGK3 | 0.56889237 |
82 | SGK1 | 0.56528715 |
83 | DYRK1B | 0.56145205 |
84 | PRKCZ | 0.54690763 |
85 | CSNK1E | 0.54642074 |
86 | MAPK10 | 0.54230754 |
87 | PRKCH | 0.53881940 |
88 | TNK2 | 0.53708861 |
89 | MAP3K6 | 0.51675582 |
90 | RPS6KA3 | 0.50648152 |
91 | PKN1 | 0.50522249 |
92 | SGK2 | 0.47831571 |
93 | CAMK4 | 0.47511472 |
94 | ERBB3 | 0.45788792 |
95 | PTK6 | 0.45444758 |
96 | BRSK1 | 0.44668723 |
97 | CSNK1G3 | 0.44122033 |
98 | NME1 | 0.43882905 |
99 | RIPK1 | 0.42842908 |
100 | BCR | 0.42398355 |
101 | MAP3K10 | 0.41260035 |
102 | FYN | 0.40768457 |
103 | MAP2K2 | 0.40436322 |
104 | RPS6KA2 | 0.39804435 |
105 | PTK2B | 0.39547585 |
106 | ERBB2 | 0.39042769 |
107 | SGK494 | 0.38538923 |
108 | SGK223 | 0.38538923 |
109 | MET | 0.38526672 |
110 | FER | 0.38000149 |
111 | GSK3B | 0.36906263 |
112 | MAPK9 | 0.36344848 |
113 | MAPK8 | 0.35267166 |
114 | CSNK1A1L | 0.34617236 |
115 | PAK2 | 0.33499295 |
116 | WNK1 | 0.33489119 |
117 | CSNK1D | 0.33165334 |
118 | PDK1 | 0.33118696 |
119 | MAP3K13 | 0.32744045 |
120 | CDK12 | 0.32732220 |
121 | PRKCB | 0.32233993 |
122 | BMX | 0.31752637 |
123 | FGFR1 | 0.31450140 |
124 | LMTK2 | 0.31160123 |
125 | FGFR2 | 0.30638570 |
126 | ROCK2 | 0.30186184 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nicotine addiction_Homo sapiens_hsa05033 | 3.86556019 |
2 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 3.00901206 |
3 | Long-term potentiation_Homo sapiens_hsa04720 | 2.69071347 |
4 | GABAergic synapse_Homo sapiens_hsa04727 | 2.58295958 |
5 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.55284213 |
6 | Circadian entrainment_Homo sapiens_hsa04713 | 2.53849727 |
7 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.52988550 |
8 | Olfactory transduction_Homo sapiens_hsa04740 | 2.48611027 |
9 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.42270223 |
10 | Morphine addiction_Homo sapiens_hsa05032 | 2.33272486 |
11 | Dopaminergic synapse_Homo sapiens_hsa04728 | 2.23044574 |
12 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 2.12280467 |
13 | Salivary secretion_Homo sapiens_hsa04970 | 1.93119748 |
14 | Insulin secretion_Homo sapiens_hsa04911 | 1.81741180 |
15 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.80348302 |
16 | Taste transduction_Homo sapiens_hsa04742 | 1.73666781 |
17 | Long-term depression_Homo sapiens_hsa04730 | 1.70492858 |
18 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.69613016 |
19 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.67940289 |
20 | Cocaine addiction_Homo sapiens_hsa05030 | 1.67939236 |
21 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.67585124 |
22 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.61646380 |
23 | Axon guidance_Homo sapiens_hsa04360 | 1.57564448 |
24 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.55409099 |
25 | Gap junction_Homo sapiens_hsa04540 | 1.55229574 |
26 | Renin secretion_Homo sapiens_hsa04924 | 1.51058012 |
27 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.46560680 |
28 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.45473635 |
29 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.39719675 |
30 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.35180680 |
31 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.34868389 |
32 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.32214869 |
33 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.30264825 |
34 | Melanogenesis_Homo sapiens_hsa04916 | 1.25019977 |
35 | Glioma_Homo sapiens_hsa05214 | 1.24894531 |
36 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.24606491 |
37 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.21103527 |
38 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.17464156 |
39 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.17106488 |
40 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.17072220 |
41 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.09415887 |
42 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.97408147 |
43 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.93719472 |
44 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.93656195 |
45 | Alcoholism_Homo sapiens_hsa05034 | 0.92892239 |
46 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.91304764 |
47 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.90839535 |
48 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.89633008 |
49 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.89625778 |
50 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.89030882 |
51 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.88187961 |
52 | Endometrial cancer_Homo sapiens_hsa05213 | 0.85157670 |
53 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.84369627 |
54 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.83764805 |
55 | Colorectal cancer_Homo sapiens_hsa05210 | 0.83002312 |
56 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.82889198 |
57 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.81511209 |
58 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.81440816 |
59 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.80454959 |
60 | Bile secretion_Homo sapiens_hsa04976 | 0.79570258 |
61 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.79453201 |
62 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.78507735 |
63 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.77119302 |
64 | Adherens junction_Homo sapiens_hsa04520 | 0.74795266 |
65 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.73331567 |
66 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.72956512 |
67 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.72761100 |
68 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.72650042 |
69 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.71402117 |
70 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.71170553 |
71 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.69418277 |
72 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.68898914 |
73 | Phototransduction_Homo sapiens_hsa04744 | 0.68607879 |
74 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.68186010 |
75 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.65941166 |
76 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.65393489 |
77 | Lysine degradation_Homo sapiens_hsa00310 | 0.64191054 |
78 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.62412080 |
79 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.62388002 |
80 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.61879968 |
81 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.61030321 |
82 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.60681653 |
83 | Focal adhesion_Homo sapiens_hsa04510 | 0.60057552 |
84 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.59494986 |
85 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.57958298 |
86 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.57605347 |
87 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.57272009 |
88 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.57222553 |
89 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.56502617 |
90 | Thyroid cancer_Homo sapiens_hsa05216 | 0.56224164 |
91 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.55952425 |
92 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.55776628 |
93 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.54050901 |
94 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.53808637 |
95 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.53361286 |
96 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.53361043 |
97 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.52581532 |
98 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.52195425 |
99 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.50524629 |
100 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.50263160 |
101 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.50037387 |
102 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.49638633 |
103 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.48448038 |
104 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.48378041 |
105 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.47863641 |
106 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.46420827 |
107 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.46169713 |
108 | Endocytosis_Homo sapiens_hsa04144 | 0.44841469 |
109 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.44382601 |
110 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.44011251 |
111 | Tight junction_Homo sapiens_hsa04530 | 0.43590366 |
112 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.42213624 |
113 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.39838016 |
114 | Prion diseases_Homo sapiens_hsa05020 | 0.38361172 |
115 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.38165000 |
116 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.34812036 |
117 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.33400939 |
118 | Circadian rhythm_Homo sapiens_hsa04710 | 0.30679359 |
119 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.28971113 |