Rank | Gene Set | Z-score |
---|---|---|
1 | exogenous drug catabolic process (GO:0042738) | 9.44425769 |
2 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 7.66721966 |
3 | L-phenylalanine catabolic process (GO:0006559) | 7.66721966 |
4 | epoxygenase P450 pathway (GO:0019373) | 7.58986896 |
5 | L-phenylalanine metabolic process (GO:0006558) | 7.31530731 |
6 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 7.31530731 |
7 | omega-hydroxylase P450 pathway (GO:0097267) | 7.21953307 |
8 | aromatic amino acid family catabolic process (GO:0009074) | 6.96074149 |
9 | indole-containing compound catabolic process (GO:0042436) | 6.34019913 |
10 | indolalkylamine catabolic process (GO:0046218) | 6.34019913 |
11 | tryptophan catabolic process (GO:0006569) | 6.34019913 |
12 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 6.24226814 |
13 | kynurenine metabolic process (GO:0070189) | 6.18328533 |
14 | oxidative demethylation (GO:0070989) | 6.10596984 |
15 | drug metabolic process (GO:0017144) | 6.00126467 |
16 | tryptophan metabolic process (GO:0006568) | 5.95553367 |
17 | * bile acid biosynthetic process (GO:0006699) | 5.90430311 |
18 | glyoxylate metabolic process (GO:0046487) | 5.82414039 |
19 | urea cycle (GO:0000050) | 5.77384900 |
20 | urea metabolic process (GO:0019627) | 5.77384900 |
21 | alpha-linolenic acid metabolic process (GO:0036109) | 5.61687092 |
22 | phenylpropanoid metabolic process (GO:0009698) | 5.61021409 |
23 | negative regulation of fibrinolysis (GO:0051918) | 5.59297708 |
24 | complement activation, alternative pathway (GO:0006957) | 5.53685254 |
25 | high-density lipoprotein particle remodeling (GO:0034375) | 5.47688460 |
26 | regulation of protein activation cascade (GO:2000257) | 5.47269058 |
27 | cysteine metabolic process (GO:0006534) | 5.41464399 |
28 | regulation of fibrinolysis (GO:0051917) | 5.40826674 |
29 | protein carboxylation (GO:0018214) | 5.39565250 |
30 | peptidyl-glutamic acid carboxylation (GO:0017187) | 5.39565250 |
31 | sulfur amino acid catabolic process (GO:0000098) | 5.39431640 |
32 | nitrogen cycle metabolic process (GO:0071941) | 5.30844653 |
33 | serine family amino acid catabolic process (GO:0009071) | 5.17071693 |
34 | regulation of plasminogen activation (GO:0010755) | 5.12751480 |
35 | regulation of complement activation (GO:0030449) | 5.12743765 |
36 | aromatic amino acid family metabolic process (GO:0009072) | 5.05069528 |
37 | negative regulation of blood coagulation (GO:0030195) | 5.03847064 |
38 | negative regulation of hemostasis (GO:1900047) | 5.03847064 |
39 | * bile acid metabolic process (GO:0008206) | 5.03695297 |
40 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 4.96786484 |
41 | S-adenosylmethionine metabolic process (GO:0046500) | 4.88815572 |
42 | homocysteine metabolic process (GO:0050667) | 4.88267235 |
43 | tyrosine metabolic process (GO:0006570) | 4.85663002 |
44 | regulation of triglyceride catabolic process (GO:0010896) | 4.83376041 |
45 | ethanol metabolic process (GO:0006067) | 4.76365282 |
46 | reverse cholesterol transport (GO:0043691) | 4.76113578 |
47 | regulation of cholesterol esterification (GO:0010872) | 4.74324997 |
48 | polyketide metabolic process (GO:0030638) | 4.73773239 |
49 | doxorubicin metabolic process (GO:0044598) | 4.73773239 |
50 | daunorubicin metabolic process (GO:0044597) | 4.73773239 |
51 | alpha-amino acid catabolic process (GO:1901606) | 4.70856926 |
52 | protein-lipid complex remodeling (GO:0034368) | 4.69144628 |
53 | macromolecular complex remodeling (GO:0034367) | 4.69144628 |
54 | plasma lipoprotein particle remodeling (GO:0034369) | 4.69144628 |
55 | lysine catabolic process (GO:0006554) | 4.66681419 |
56 | lysine metabolic process (GO:0006553) | 4.66681419 |
57 | alkaloid metabolic process (GO:0009820) | 4.66678334 |
58 | amino-acid betaine metabolic process (GO:0006577) | 4.63192305 |
59 | triglyceride homeostasis (GO:0070328) | 4.61335338 |
60 | acylglycerol homeostasis (GO:0055090) | 4.61335338 |
61 | negative regulation of coagulation (GO:0050819) | 4.59234508 |
62 | negative regulation of wound healing (GO:0061045) | 4.53680046 |
63 | negative regulation of cholesterol transport (GO:0032375) | 4.51630768 |
64 | negative regulation of sterol transport (GO:0032372) | 4.51630768 |
65 | coenzyme catabolic process (GO:0009109) | 4.50675399 |
66 | indolalkylamine metabolic process (GO:0006586) | 4.48859842 |
67 | phospholipid efflux (GO:0033700) | 4.47341596 |
68 | imidazole-containing compound metabolic process (GO:0052803) | 4.43028446 |
69 | cellular ketone body metabolic process (GO:0046950) | 4.41156957 |
70 | amine catabolic process (GO:0009310) | 4.39570033 |
71 | cellular biogenic amine catabolic process (GO:0042402) | 4.39570033 |
72 | cellular glucuronidation (GO:0052695) | 4.34946409 |
73 | hormone catabolic process (GO:0042447) | 4.34924431 |
74 | cellular amino acid catabolic process (GO:0009063) | 4.32613412 |
75 | intestinal cholesterol absorption (GO:0030299) | 4.30975007 |
76 | plasma lipoprotein particle clearance (GO:0034381) | 4.29806665 |
77 | glutamate metabolic process (GO:0006536) | 4.27883934 |
78 | positive regulation of hemostasis (GO:1900048) | 4.26624582 |
79 | positive regulation of blood coagulation (GO:0030194) | 4.26624582 |
80 | fat-soluble vitamin biosynthetic process (GO:0042362) | 4.25064640 |
81 | aminoglycoside antibiotic metabolic process (GO:0030647) | 4.20409522 |
82 | ethanol oxidation (GO:0006069) | 4.18531692 |
83 | benzene-containing compound metabolic process (GO:0042537) | 4.17724788 |
84 | * bile acid and bile salt transport (GO:0015721) | 4.16737441 |
85 | cholesterol efflux (GO:0033344) | 4.15380121 |
86 | negative regulation of protein activation cascade (GO:2000258) | 4.15039616 |
87 | acute-phase response (GO:0006953) | 4.14207877 |
88 | * glycine metabolic process (GO:0006544) | 4.13346718 |
89 | flavonoid metabolic process (GO:0009812) | 4.11013975 |
90 | regulation of humoral immune response (GO:0002920) | 4.08926504 |
91 | cellular modified amino acid catabolic process (GO:0042219) | 4.08177678 |
92 | dicarboxylic acid biosynthetic process (GO:0043650) | 4.07722442 |
93 | arginine metabolic process (GO:0006525) | 4.06659807 |
94 | serine family amino acid biosynthetic process (GO:0009070) | 4.05913916 |
95 | * serine family amino acid metabolic process (GO:0009069) | 4.04162694 |
96 | heme transport (GO:0015886) | 4.03966205 |
97 | aldehyde catabolic process (GO:0046185) | 4.02621602 |
98 | fibrinolysis (GO:0042730) | 4.00414756 |
99 | low-density lipoprotein particle remodeling (GO:0034374) | 3.96289091 |
100 | positive regulation of coagulation (GO:0050820) | 3.94905394 |
101 | plasma lipoprotein particle assembly (GO:0034377) | 3.91727002 |
102 | response to mercury ion (GO:0046689) | 3.90729952 |
103 | primary alcohol catabolic process (GO:0034310) | 3.89982257 |
104 | complement activation, classical pathway (GO:0006958) | 3.88751101 |
105 | cytolysis (GO:0019835) | 3.87933018 |
106 | uronic acid metabolic process (GO:0006063) | 3.86134944 |
107 | glucuronate metabolic process (GO:0019585) | 3.86134944 |
108 | drug catabolic process (GO:0042737) | 3.85269350 |
109 | cofactor catabolic process (GO:0051187) | 3.83926655 |
110 | blood coagulation, intrinsic pathway (GO:0007597) | 3.83871187 |
111 | complement activation (GO:0006956) | 3.83530407 |
112 | ketone body metabolic process (GO:1902224) | 3.81917097 |
113 | steroid catabolic process (GO:0006706) | 3.80044698 |
114 | regulation of bile acid biosynthetic process (GO:0070857) | 3.79419797 |
115 | protein activation cascade (GO:0072376) | 3.78147405 |
116 | carboxylic acid catabolic process (GO:0046395) | 3.77229859 |
117 | organic acid catabolic process (GO:0016054) | 3.77229859 |
118 | acetyl-CoA metabolic process (GO:0006084) | 3.76049012 |
119 | positive regulation of lipoprotein lipase activity (GO:0051006) | 3.73004713 |
120 | positive regulation of triglyceride lipase activity (GO:0061365) | 3.73004713 |
121 | very-low-density lipoprotein particle assembly (GO:0034379) | 3.72995111 |
122 | cholesterol homeostasis (GO:0042632) | 3.71540019 |
123 | xenobiotic metabolic process (GO:0006805) | 3.71187254 |
124 | positive regulation of lipid catabolic process (GO:0050996) | 3.70667324 |
125 | phospholipid homeostasis (GO:0055091) | 3.70563777 |
126 | L-methionine salvage (GO:0071267) | 3.69301641 |
127 | L-methionine biosynthetic process (GO:0071265) | 3.69301641 |
128 | amino acid salvage (GO:0043102) | 3.69301641 |
129 | negative regulation of lipase activity (GO:0060192) | 3.68810207 |
130 | short-chain fatty acid metabolic process (GO:0046459) | 3.65770559 |
131 | regulation of cholesterol homeostasis (GO:2000188) | 3.65586619 |
132 | sterol homeostasis (GO:0055092) | 3.65512301 |
133 | regulation of lipoprotein particle clearance (GO:0010984) | 3.64001148 |
134 | NAD biosynthetic process (GO:0009435) | 3.60335800 |
135 | negative regulation of fatty acid biosynthetic process (GO:0045717) | 3.58975645 |
136 | nicotinamide nucleotide biosynthetic process (GO:0019359) | 3.56494938 |
137 | pyridine nucleotide biosynthetic process (GO:0019363) | 3.56494938 |
138 | plasma lipoprotein particle organization (GO:0071827) | 3.55776747 |
139 | drug transmembrane transport (GO:0006855) | 3.54195536 |
Rank | Gene Set | Z-score |
---|---|---|
1 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 8.41379273 |
2 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 7.20976904 |
3 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 7.12414967 |
4 | * LXR_22158963_ChIP-Seq_LIVER_Mouse | 6.49599702 |
5 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 5.31938064 |
6 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 5.11388603 |
7 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 4.74932999 |
8 | * NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 4.02590272 |
9 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 4.02201955 |
10 | TCF7L2_21901280_ChIP-Seq_H4IIE_Rat | 2.07857253 |
11 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 12.0061953 |
12 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.95760617 |
13 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.95182471 |
14 | * FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.58633082 |
15 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.52977936 |
16 | * HTT_18923047_ChIP-ChIP_STHdh_Human | 1.48501401 |
17 | GATA1_22025678_ChIP-Seq_K562_Human | 1.42484856 |
18 | * HNF4A_19822575_ChIP-Seq_HepG2_Human | 1.39566192 |
19 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.23831764 |
20 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.20024795 |
21 | * RXRA_24833708_ChIP-Seq_LIVER_Mouse | 1.17963687 |
22 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.16763932 |
23 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.06905919 |
24 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.02834873 |
25 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.00271208 |
26 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.99868465 |
27 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.99059365 |
28 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.98469914 |
29 | HNFA_21074721_ChIP-Seq_CACO-2_Human | 0.96719604 |
30 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 0.93140717 |
31 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 0.91420197 |
32 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 0.90309771 |
33 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 0.90250097 |
34 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.86217748 |
35 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.85067796 |
36 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.83379064 |
37 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 0.82689133 |
38 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 0.81949958 |
39 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.81322834 |
40 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.81312191 |
41 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 0.80010758 |
42 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.79102454 |
43 | TP53_18474530_ChIP-ChIP_U2OS_Human | 0.78644079 |
44 | GATA4_25053715_ChIP-Seq_YYC3_Human | 0.78571122 |
45 | NFYA_21822215_ChIP-Seq_K562_Human | 0.78196732 |
46 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.77754093 |
47 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.77401223 |
48 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.77361691 |
49 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 0.75812879 |
50 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.75538483 |
51 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.75293127 |
52 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 0.73678649 |
53 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.73347094 |
54 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.72924257 |
55 | SOX2_21211035_ChIP-Seq_LN229_Human | 0.71691661 |
56 | * RARA_24833708_ChIP-Seq_LIVER_Mouse | 0.71283132 |
57 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.71215104 |
58 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.71040159 |
59 | CBX2_22325352_ChIP-Seq_293T-Rex_Human | 0.68984636 |
60 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.67992892 |
61 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.67831060 |
62 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.67240163 |
63 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.67240163 |
64 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.67091462 |
65 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 0.66971838 |
66 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.65714941 |
67 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.65679847 |
68 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.65605723 |
69 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.65584165 |
70 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.64972179 |
71 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 0.64074204 |
72 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 0.62492151 |
73 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.61965604 |
74 | * RARB_24833708_ChIP-Seq_LIVER_Mouse | 0.61402333 |
75 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.60848361 |
76 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.60787484 |
77 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.60764739 |
78 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 0.60710363 |
79 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 0.60371197 |
80 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 0.60032594 |
81 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 0.59408403 |
82 | ETV1_20927104_ChIP-Seq_GIST48_Human | 0.58960471 |
83 | ESRRB_18555785_Chip-Seq_ESCs_Mouse | 0.58722758 |
84 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 0.58567285 |
85 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.58115133 |
86 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.57650413 |
87 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.57025176 |
88 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.55909370 |
89 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.54600523 |
90 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 0.53826277 |
91 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.53535399 |
92 | NFYB_21822215_ChIP-Seq_K562_Human | 0.53333167 |
93 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 0.53223049 |
94 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.53211727 |
95 | PU1_27457419_Chip-Seq_LIVER_Mouse | 0.53091695 |
96 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 0.52948177 |
97 | AR_20517297_ChIP-Seq_VCAP_Human | 0.52231904 |
98 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.51912862 |
99 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.51549233 |
100 | MYC_19915707_ChIP-ChIP_AK7_Human | 0.51430837 |
101 | FOXA1_26743006_Chip-Seq_LNCaP-abl_Human | 0.50974478 |
102 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 0.50951332 |
103 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.50145530 |
104 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.50090158 |
105 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.49890224 |
106 | ESET_19884257_ChIP-Seq_ESCs_Mouse | 0.49659156 |
107 | CBP_21632823_ChIP-Seq_H3396_Human | 0.48885893 |
108 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 0.48548760 |
109 | STAT1_17558387_ChIP-Seq_HELA_Human | 0.48182152 |
110 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.46260293 |
111 | PPARG_20887899_ChIP-Seq_3T3-L1_Mouse | 0.45729294 |
112 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 0.44694808 |
113 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 0.43814970 |
114 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.42786945 |
115 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.42611637 |
116 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.42338884 |
117 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.42072453 |
118 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 0.41715769 |
119 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.41646872 |
120 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.41304761 |
121 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.41098859 |
122 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.40921860 |
123 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.39992880 |
124 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.38891386 |
125 | GATA1_19941826_ChIP-Seq_K562_Human | 0.38657291 |
126 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.38496256 |
127 | STAT3_19079543_ChIP-ChIP_MESCs_Mouse | 0.37910788 |
128 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.37707550 |
129 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 0.37672488 |
130 | GATA2_19941826_ChIP-Seq_K562_Human | 0.37421963 |
131 | GATA6_25053715_ChIP-Seq_YYC3_Human | 0.37344617 |
132 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.37327903 |
133 | LUZP1_20508642_ChIP-Seq_ESCs_Mouse | 0.36017363 |
134 | SPI1_26923725_Chip-Seq_HPCs_Mouse | 0.35270372 |
135 | * MYC_27129775_Chip-Seq_CORNEA_Mouse | 0.34627978 |
136 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.34038088 |
137 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.33624882 |
138 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.33392610 |
139 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.33168264 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0002139_abnormal_hepatobiliary_system | 8.34565508 |
2 | MP0005360_urolithiasis | 7.59102529 |
3 | MP0005085_abnormal_gallbladder_physiolo | 6.53183077 |
4 | MP0005365_abnormal_bile_salt | 6.21925593 |
5 | MP0008875_abnormal_xenobiotic_pharmacok | 5.12975327 |
6 | MP0003806_abnormal_nucleotide_metabolis | 4.32698167 |
7 | MP0003252_abnormal_bile_duct | 3.97548363 |
8 | MP0010329_abnormal_lipoprotein_level | 3.56755036 |
9 | MP0009840_abnormal_foam_cell | 3.20183331 |
10 | MP0005083_abnormal_biliary_tract | 3.04919322 |
11 | MP0003195_calcinosis | 2.81531767 |
12 | MP0005332_abnormal_amino_acid | 2.75633549 |
13 | MP0001666_abnormal_nutrient_absorption | 2.61195912 |
14 | MP0003191_abnormal_cellular_cholesterol | 2.23048427 |
15 | MP0000609_abnormal_liver_physiology | 2.15899387 |
16 | MP0004019_abnormal_vitamin_homeostasis | 2.11210051 |
17 | MP0002118_abnormal_lipid_homeostasis | 2.09727186 |
18 | MP0003868_abnormal_feces_composition | 1.98405981 |
19 | MP0002138_abnormal_hepatobiliary_system | 1.96909282 |
20 | MP0005319_abnormal_enzyme/_coenzyme | 1.83406300 |
21 | MP0001764_abnormal_homeostasis | 1.68064592 |
22 | MP0009697_abnormal_copulation | 1.61993181 |
23 | MP0005584_abnormal_enzyme/coenzyme_acti | 1.56405621 |
24 | MP0005451_abnormal_body_composition | 1.40824534 |
25 | MP0003011_delayed_dark_adaptation | 1.35251284 |
26 | MP0003186_abnormal_redox_activity | 1.25616180 |
27 | MP0003656_abnormal_erythrocyte_physiolo | 1.22394567 |
28 | MP0009643_abnormal_urine_homeostasis | 1.21150296 |
29 | MP0000598_abnormal_liver_morphology | 1.17245063 |
30 | MP0005647_abnormal_sex_gland | 1.16590682 |
31 | MP0003705_abnormal_hypodermis_morpholog | 1.14734234 |
32 | MP0009764_decreased_sensitivity_to | 1.05135657 |
33 | MP0000604_amyloidosis | 1.04965049 |
34 | MP0009763_increased_sensitivity_to | 1.01640163 |
35 | MP0002254_reproductive_system_inflammat | 1.00546104 |
36 | MP0010368_abnormal_lymphatic_system | 0.94613074 |
37 | MP0001915_intracranial_hemorrhage | 0.91958114 |
38 | MP0005636_abnormal_mineral_homeostasis | 0.89840829 |
39 | MP0008469_abnormal_protein_level | 0.88490674 |
40 | MP0009642_abnormal_blood_homeostasis | 0.86084745 |
41 | MP0005408_hypopigmentation | 0.85411292 |
42 | MP0005187_abnormal_penis_morphology | 0.81397753 |
43 | MP0006036_abnormal_mitochondrial_physio | 0.81070818 |
44 | MP0002132_abnormal_respiratory_system | 0.80380480 |
45 | MP0005376_homeostasis/metabolism_phenot | 0.79571848 |
46 | MP0005670_abnormal_white_adipose | 0.79464580 |
47 | MP0009765_abnormal_xenobiotic_induced | 0.77910261 |
48 | MP0002876_abnormal_thyroid_physiology | 0.77065236 |
49 | MP0002078_abnormal_glucose_homeostasis | 0.76533066 |
50 | MP0005084_abnormal_gallbladder_morpholo | 0.76384602 |
51 | MP0005220_abnormal_exocrine_pancreas | 0.73754721 |
52 | MP0002971_abnormal_brown_adipose | 0.71029740 |
53 | MP0004130_abnormal_muscle_cell | 0.69040269 |
54 | MP0005334_abnormal_fat_pad | 0.68561673 |
55 | MP0005535_abnormal_body_temperature | 0.67970214 |
56 | MP0003690_abnormal_glial_cell | 0.67593753 |
57 | MP0001661_extended_life_span | 0.66264145 |
58 | MP0005266_abnormal_metabolism | 0.65561561 |
59 | MP0009053_abnormal_anal_canal | 0.64129691 |
60 | MP0003879_abnormal_hair_cell | 0.62320788 |
61 | MP0003329_amyloid_beta_deposits | 0.61741348 |
62 | MP0000639_abnormal_adrenal_gland | 0.59870018 |
63 | MP0006035_abnormal_mitochondrial_morpho | 0.57794551 |
64 | MP0005058_abnormal_lysosome_morphology | 0.56554587 |
65 | MP0001756_abnormal_urination | 0.56361508 |
66 | MP0005448_abnormal_energy_balance | 0.53710624 |
67 | MP0005464_abnormal_platelet_physiology | 0.49913837 |
68 | MP0002822_catalepsy | 0.49350656 |
69 | MP0005023_abnormal_wound_healing | 0.48260775 |
70 | MP0004381_abnormal_hair_follicle | 0.48102203 |
71 | MP0005395_other_phenotype | 0.46977830 |
72 | MP0002928_abnormal_bile_duct | 0.46808260 |
73 | MP0003718_maternal_effect | 0.45758927 |
74 | MP0002282_abnormal_trachea_morphology | 0.45534498 |
75 | MP0008874_decreased_physiological_sensi | 0.45522529 |
76 | MP0003638_abnormal_response/metabolism_ | 0.45369037 |
77 | MP0008873_increased_physiological_sensi | 0.44523992 |
78 | MP0002136_abnormal_kidney_physiology | 0.43178073 |
79 | MP0003724_increased_susceptibility_to | 0.42809221 |
80 | MP0004782_abnormal_surfactant_physiolog | 0.41994266 |
81 | MP0003436_decreased_susceptibility_to | 0.41757436 |
82 | MP0002837_dystrophic_cardiac_calcinosis | 0.41087675 |
83 | MP0005248_abnormal_Harderian_gland | 0.40407256 |
84 | MP0003953_abnormal_hormone_level | 0.39609832 |
85 | MP0005166_decreased_susceptibility_to | 0.39579308 |
86 | MP0003075_altered_response_to | 0.39498261 |
87 | MP0000579_abnormal_nail_morphology | 0.38124275 |
88 | MP0003959_abnormal_lean_body | 0.37284813 |
89 | MP0009384_cardiac_valve_regurgitation | 0.36142801 |
90 | MP0009672_abnormal_birth_weight | 0.35978317 |
91 | MP0008872_abnormal_physiological_respon | 0.35765201 |
92 | MP0005666_abnormal_adipose_tissue | 0.35602565 |
93 | MP0002796_impaired_skin_barrier | 0.33225850 |
94 | MP0005197_abnormal_uvea_morphology | 0.32327369 |
95 | MP0009785_altered_susceptibility_to | 0.32140107 |
96 | MP0006082_CNS_inflammation | 0.32118366 |
97 | MP0009115_abnormal_fat_cell | 0.31738078 |
98 | MP0000230_abnormal_systemic_arterial | 0.31596119 |
99 | MP0000249_abnormal_blood_vessel | 0.30416270 |
100 | MP0002249_abnormal_larynx_morphology | 0.30250918 |
101 | MP0001243_abnormal_dermal_layer | 0.30027266 |
102 | MP0002970_abnormal_white_adipose | 0.29614110 |
103 | MP0001853_heart_inflammation | 0.29196961 |
104 | MP0002168_other_aberrant_phenotype | 0.29111630 |
105 | MP0004883_abnormal_blood_vessel | 0.27961262 |
106 | MP0001881_abnormal_mammary_gland | 0.27667118 |
107 | MP0000566_synostosis | 0.26896285 |
108 | MP0001845_abnormal_inflammatory_respons | 0.26831755 |
109 | MP0002089_abnormal_postnatal_growth/wei | 0.25370303 |
110 | MP0002060_abnormal_skin_morphology | 0.24398375 |
111 | MP0000920_abnormal_myelination | 0.23911015 |
112 | MP0002090_abnormal_vision | 0.23749200 |
113 | MP0000427_abnormal_hair_cycle | 0.23471416 |
114 | MP0001851_eye_inflammation | 0.23208634 |
115 | MP0005164_abnormal_response_to | 0.22959297 |
116 | MP0010386_abnormal_urinary_bladder | 0.22394247 |
117 | MP0003632_abnormal_nervous_system | 0.21027059 |
118 | MP0004142_abnormal_muscle_tone | 0.19571064 |
119 | MP0000467_abnormal_esophagus_morphology | 0.17008600 |
120 | MP0000371_diluted_coat_color | 0.16583611 |
121 | MP0002697_abnormal_eye_size | 0.15688027 |
122 | MP0002128_abnormal_blood_circulation | 0.14882302 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Intrahepatic cholestasis (HP:0001406) | 7.50376648 |
2 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 7.47956278 |
3 | Deep venous thrombosis (HP:0002625) | 7.47318781 |
4 | Prolonged partial thromboplastin time (HP:0003645) | 6.64735170 |
5 | Hypobetalipoproteinemia (HP:0003563) | 6.48286098 |
6 | * Abnormality of monocarboxylic acid metabolism (HP:0010996) | 6.32513963 |
7 | Xanthomatosis (HP:0000991) | 6.32044723 |
8 | Complement deficiency (HP:0004431) | 5.65889007 |
9 | Hyperlipoproteinemia (HP:0010980) | 5.61503951 |
10 | Joint hemorrhage (HP:0005261) | 4.80775290 |
11 | Hypolipoproteinemia (HP:0010981) | 4.79531588 |
12 | Hyperammonemia (HP:0001987) | 4.64338893 |
13 | Epidermoid cyst (HP:0200040) | 4.63055213 |
14 | Hyperglycinemia (HP:0002154) | 4.50722512 |
15 | Abnormality of the common coagulation pathway (HP:0010990) | 4.50166686 |
16 | Abnormality of the level of lipoprotein cholesterol (HP:0010979) | 4.39711676 |
17 | Abnormality of methionine metabolism (HP:0010901) | 4.33972470 |
18 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 4.30555113 |
19 | Ketosis (HP:0001946) | 4.25301350 |
20 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 4.17820810 |
21 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 4.16231052 |
22 | Hypoalphalipoproteinemia (HP:0003233) | 4.15191449 |
23 | Abnormality of complement system (HP:0005339) | 4.12921687 |
24 | Abnormality of serine family amino acid metabolism (HP:0010894) | 3.93443841 |
25 | Abnormality of glycine metabolism (HP:0010895) | 3.93443841 |
26 | Hyperglycinuria (HP:0003108) | 3.93173264 |
27 | Abnormality of pyrimidine metabolism (HP:0004353) | 3.90273182 |
28 | * Fat malabsorption (HP:0002630) | 3.83346646 |
29 | Hypoglycemic coma (HP:0001325) | 3.82595573 |
30 | Abnormality of the intrinsic pathway (HP:0010989) | 3.81808953 |
31 | Conjugated hyperbilirubinemia (HP:0002908) | 3.80670041 |
32 | Hypercholesterolemia (HP:0003124) | 3.61660043 |
33 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 3.40321298 |
34 | Hyperbilirubinemia (HP:0002904) | 3.35659603 |
35 | Abnormality of fatty-acid metabolism (HP:0004359) | 3.34087795 |
36 | Osteomalacia (HP:0002749) | 3.21152550 |
37 | Delayed CNS myelination (HP:0002188) | 3.13405660 |
38 | Abnormality of serum amino acid levels (HP:0003112) | 3.12982678 |
39 | Abnormality of nucleobase metabolism (HP:0010932) | 3.07193891 |
40 | Spontaneous abortion (HP:0005268) | 3.05514975 |
41 | Hypochromic microcytic anemia (HP:0004840) | 2.99960148 |
42 | Ketoacidosis (HP:0001993) | 2.99806265 |
43 | Myocardial infarction (HP:0001658) | 2.99670537 |
44 | Hepatocellular carcinoma (HP:0001402) | 2.99257021 |
45 | Skin nodule (HP:0200036) | 2.86287842 |
46 | Systemic lupus erythematosus (HP:0002725) | 2.82167851 |
47 | Reduced antithrombin III activity (HP:0001976) | 2.80820106 |
48 | Metabolic acidosis (HP:0001942) | 2.74982433 |
49 | Abnormality of purine metabolism (HP:0004352) | 2.65654246 |
50 | * Steatorrhea (HP:0002570) | 2.62242067 |
51 | Purpura (HP:0000979) | 2.62013943 |
52 | Lethargy (HP:0001254) | 2.61808199 |
53 | Dicarboxylic aciduria (HP:0003215) | 2.56399670 |
54 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.56399670 |
55 | Vascular calcification (HP:0004934) | 2.56034529 |
56 | Acanthocytosis (HP:0001927) | 2.55741798 |
57 | Spastic diplegia (HP:0001264) | 2.51778567 |
58 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.51083944 |
59 | Abnormal gallbladder morphology (HP:0012437) | 2.49167909 |
60 | Hyperphosphaturia (HP:0003109) | 2.49010600 |
61 | Hypoglycemic seizures (HP:0002173) | 2.45229702 |
62 | Mitral stenosis (HP:0001718) | 2.45010118 |
63 | Glomerulonephritis (HP:0000099) | 2.44117330 |
64 | Cerebral edema (HP:0002181) | 2.44112862 |
65 | Gout (HP:0001997) | 2.42590078 |
66 | Cholelithiasis (HP:0001081) | 2.42221660 |
67 | Neonatal onset (HP:0003623) | 2.40962773 |
68 | Arthropathy (HP:0003040) | 2.40790279 |
69 | * Rickets (HP:0002748) | 2.38672051 |
70 | Irritability (HP:0000737) | 2.36401910 |
71 | Abnormal gallbladder physiology (HP:0012438) | 2.35715778 |
72 | Cholecystitis (HP:0001082) | 2.35715778 |
73 | Abnormality of urine glucose concentration (HP:0011016) | 2.34826329 |
74 | Glycosuria (HP:0003076) | 2.34826329 |
75 | Fair hair (HP:0002286) | 2.30912484 |
76 | Cardiovascular calcification (HP:0011915) | 2.26913467 |
77 | Amyloidosis (HP:0011034) | 2.25716520 |
78 | Malnutrition (HP:0004395) | 2.25227483 |
79 | Abnormality of the Achilles tendon (HP:0005109) | 2.20985390 |
80 | Gingival bleeding (HP:0000225) | 2.20329561 |
81 | Sensorimotor neuropathy (HP:0007141) | 2.19784139 |
82 | Esophageal varix (HP:0002040) | 2.17701222 |
83 | Bifid scrotum (HP:0000048) | 2.16423152 |
84 | Brushfield spots (HP:0001088) | 2.14025449 |
85 | Pancreatitis (HP:0001733) | 2.13679715 |
86 | Menorrhagia (HP:0000132) | 2.12115167 |
87 | Enlarged kidneys (HP:0000105) | 2.10404780 |
88 | Late onset (HP:0003584) | 2.09722493 |
89 | Thrombophlebitis (HP:0004418) | 2.07985736 |
90 | Vomiting (HP:0002013) | 2.05999328 |
91 | Elevated alkaline phosphatase (HP:0003155) | 2.04004103 |
92 | Abnormality of the gallbladder (HP:0005264) | 2.03310360 |
93 | Opisthotonus (HP:0002179) | 2.03259174 |
94 | Abnormal urine phosphate concentration (HP:0012599) | 2.00117733 |
95 | Generalized aminoaciduria (HP:0002909) | 1.99083650 |
96 | Hyperinsulinemic hypoglycemia (HP:0000825) | 1.98819565 |
97 | Poikilocytosis (HP:0004447) | 1.98348473 |
98 | Hemorrhage of the eye (HP:0011885) | 1.98176494 |
99 | Increased mean platelet volume (HP:0011877) | 1.93457144 |
100 | Abnormal cartilage morphology (HP:0002763) | 1.89817367 |
101 | Neonatal hypoglycemia (HP:0001998) | 1.89798324 |
102 | Abnormality of iron homeostasis (HP:0011031) | 1.89142241 |
103 | Renal cortical cysts (HP:0000803) | 1.86750905 |
104 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.86225926 |
105 | Hypophosphatemic rickets (HP:0004912) | 1.84047363 |
106 | Abnormal enzyme/coenzyme activity (HP:0012379) | 1.84011155 |
107 | Abnormality of alkaline phosphatase activity (HP:0004379) | 1.83318795 |
108 | Elevated hepatic transaminases (HP:0002910) | 1.82513043 |
109 | Joint swelling (HP:0001386) | 1.82342801 |
110 | Status epilepticus (HP:0002133) | 1.81512135 |
111 | Abnormality of proline metabolism (HP:0010907) | 1.80960389 |
112 | Hydroxyprolinuria (HP:0003080) | 1.80960389 |
113 | Alkalosis (HP:0001948) | 1.80930457 |
114 | Increased serum ferritin (HP:0003281) | 1.78108862 |
115 | Abnormal biliary tract physiology (HP:0012439) | 1.77943617 |
116 | Bile duct proliferation (HP:0001408) | 1.77943617 |
117 | Gangrene (HP:0100758) | 1.75023156 |
118 | Hyperglycemia (HP:0003074) | 1.74232692 |
119 | Abnormal platelet volume (HP:0011876) | 1.73471869 |
120 | Nephritis (HP:0000123) | 1.72710845 |
121 | Acute hepatic failure (HP:0006554) | 1.69515771 |
122 | Pulmonary embolism (HP:0002204) | 1.67219730 |
123 | Hypochromic anemia (HP:0001931) | 1.60910895 |
124 | Impaired platelet aggregation (HP:0003540) | 1.60103737 |
125 | Abnormal platelet function (HP:0011869) | 1.60103737 |
126 | Generalized hypopigmentation of hair (HP:0011358) | 1.58344924 |
127 | Epistaxis (HP:0000421) | 1.56919655 |
128 | Retinal atrophy (HP:0001105) | 1.56915614 |
129 | Atrioventricular block (HP:0001678) | 1.56786348 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BCKDK | 7.12315904 |
2 | FGFR4 | 4.62207400 |
3 | SIK1 | 4.52355534 |
4 | ERN1 | 4.47483565 |
5 | TAOK3 | 3.16366418 |
6 | ERBB4 | 3.13970073 |
7 | INSRR | 2.97733609 |
8 | MAP2K4 | 2.37997818 |
9 | MAP3K12 | 2.16553744 |
10 | PKN2 | 2.15371429 |
11 | MST1R | 2.08773257 |
12 | PRPF4B | 1.99740972 |
13 | MAPK11 | 1.94421305 |
14 | FLT3 | 1.87461348 |
15 | PIK3CG | 1.82384510 |
16 | LATS1 | 1.71565295 |
17 | TYK2 | 1.69538225 |
18 | TRIB3 | 1.67782199 |
19 | NTRK3 | 1.58559293 |
20 | ABL2 | 1.51398238 |
21 | DAPK2 | 1.49072461 |
22 | MAP3K2 | 1.49016133 |
23 | PTK6 | 1.45294093 |
24 | FGFR2 | 1.44719340 |
25 | NEK9 | 1.43008822 |
26 | MYLK | 1.41119401 |
27 | FRK | 1.39770524 |
28 | EIF2AK1 | 1.27099489 |
29 | KDR | 1.24914837 |
30 | JAK2 | 1.24411506 |
31 | MAP3K7 | 1.24058067 |
32 | PINK1 | 1.14732376 |
33 | PRKAA2 | 1.12110322 |
34 | SCYL2 | 1.09383179 |
35 | ERBB2 | 1.07958169 |
36 | GRK6 | 1.05185144 |
37 | TBK1 | 1.03741002 |
38 | MAP3K14 | 1.03234121 |
39 | JAK1 | 1.03108926 |
40 | MAP2K3 | 1.01585951 |
41 | MAP3K10 | 1.01109346 |
42 | MAPK4 | 0.99439259 |
43 | PRKCZ | 0.94415668 |
44 | CSNK1D | 0.94332458 |
45 | NLK | 0.94293109 |
46 | MAPK15 | 0.93742168 |
47 | PRKG1 | 0.92454741 |
48 | STK38L | 0.89503448 |
49 | FER | 0.85411524 |
50 | MET | 0.84209987 |
51 | MAP3K3 | 0.82411093 |
52 | PRKACA | 0.82228890 |
53 | EPHB1 | 0.81913580 |
54 | MAPK12 | 0.81384368 |
55 | BCR | 0.81180409 |
56 | CDK6 | 0.80007073 |
57 | EPHA3 | 0.77858134 |
58 | PRKACG | 0.75613025 |
59 | CAMK2G | 0.75537963 |
60 | TIE1 | 0.74094318 |
61 | CAMKK2 | 0.72014536 |
62 | STK38 | 0.70901219 |
63 | PRKCB | 0.70303273 |
64 | MAP3K11 | 0.69840580 |
65 | KSR2 | 0.69566641 |
66 | DYRK1B | 0.67837737 |
67 | MAP2K6 | 0.67247663 |
68 | CSK | 0.66751448 |
69 | GSK3A | 0.66591855 |
70 | CAMK1D | 0.66429716 |
71 | PRKAA1 | 0.66129192 |
72 | MAPKAPK3 | 0.65933259 |
73 | ZAP70 | 0.65496473 |
74 | IRAK3 | 0.65406246 |
75 | SGK3 | 0.65163544 |
76 | MAPK7 | 0.61336236 |
77 | RPS6KA3 | 0.61234164 |
78 | SGK1 | 0.59502005 |
79 | FGFR3 | 0.59023710 |
80 | TNK2 | 0.58729204 |
81 | CSNK1E | 0.58423665 |
82 | CSF1R | 0.56987290 |
83 | RIPK1 | 0.56861440 |
84 | RPS6KB1 | 0.56822252 |
85 | PDK2 | 0.56811604 |
86 | BLK | 0.54564154 |
87 | PRKCQ | 0.53080880 |
88 | IKBKE | 0.52884484 |
89 | PTK2 | 0.52816149 |
90 | TGFBR2 | 0.52358261 |
91 | MUSK | 0.51351768 |
92 | CSNK1G1 | 0.50932283 |
93 | PDPK1 | 0.50613337 |
94 | PKN1 | 0.49601112 |
95 | SRC | 0.49055766 |
96 | STK16 | 0.49004359 |
97 | PRKACB | 0.48944744 |
98 | SGK2 | 0.48654091 |
99 | EPHA4 | 0.47890857 |
100 | CASK | 0.47134790 |
101 | ARAF | 0.47026519 |
102 | MAP3K13 | 0.45392524 |
103 | NEK1 | 0.45315576 |
104 | IGF1R | 0.44799363 |
105 | PDGFRA | 0.44677754 |
106 | GRK1 | 0.44002132 |
107 | DAPK3 | 0.43736564 |
108 | PIM2 | 0.43505282 |
109 | MAP3K5 | 0.43503233 |
110 | CSNK2A1 | 0.42689826 |
111 | WNK3 | 0.41940053 |
112 | TAOK2 | 0.41796999 |
113 | RET | 0.41258731 |
114 | PRKCG | 0.40969863 |
115 | MAP2K1 | 0.40757696 |
116 | CDK4 | 0.38608404 |
117 | ICK | 0.38228991 |
118 | CSNK2A2 | 0.37840843 |
119 | CSNK1A1 | 0.36618138 |
120 | MAP3K6 | 0.36331221 |
121 | EGFR | 0.34931406 |
122 | MTOR | 0.34825639 |
123 | PBK | 0.34775973 |
124 | SGK494 | 0.33160006 |
125 | SGK223 | 0.33160006 |
126 | CSNK1G2 | 0.31817360 |
127 | CAMK4 | 0.31717358 |
128 | PDK1 | 0.30640121 |
129 | LATS2 | 0.29334082 |
130 | IRAK2 | 0.28677366 |
131 | CSNK1G3 | 0.28301458 |
132 | IRAK1 | 0.27844911 |
133 | PIK3CA | 0.26157840 |
134 | PRKCA | 0.25916707 |
135 | MAP3K1 | 0.24423485 |
136 | ABL1 | 0.23286623 |
137 | PAK3 | 0.22029526 |
138 | CAMK1G | 0.21779411 |
139 | PDK4 | 0.20937696 |
140 | PDK3 | 0.20937696 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 4.50059598 |
2 | Nitrogen metabolism_Homo sapiens_hsa00910 | 3.62214679 |
3 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 3.44540412 |
4 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 3.37931435 |
5 | Arginine biosynthesis_Homo sapiens_hsa00220 | 3.11725280 |
6 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 2.81429090 |
7 | Tryptophan metabolism_Homo sapiens_hsa00380 | 2.73752006 |
8 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 2.64533560 |
9 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 2.58046168 |
10 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.49913403 |
11 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.40242830 |
12 | * Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 2.36588100 |
13 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 2.26488643 |
14 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 2.15993994 |
15 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.15790982 |
16 | * Peroxisome_Homo sapiens_hsa04146 | 2.04404202 |
17 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.96879785 |
18 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.96644294 |
19 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.94390204 |
20 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.93311724 |
21 | Histidine metabolism_Homo sapiens_hsa00340 | 1.92445695 |
22 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.86928837 |
23 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.79768993 |
24 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.79572495 |
25 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.79516983 |
26 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.77344191 |
27 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.77239906 |
28 | Retinol metabolism_Homo sapiens_hsa00830 | 1.73824435 |
29 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.72053088 |
30 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.68764381 |
31 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.60080576 |
32 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.58810249 |
33 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.57881486 |
34 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.52207538 |
35 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.51896726 |
36 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.47597003 |
37 | * Bile secretion_Homo sapiens_hsa04976 | 1.41380451 |
38 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.36483540 |
39 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.35884910 |
40 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.34731546 |
41 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.33139946 |
42 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.29614176 |
43 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.21922780 |
44 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.21721226 |
45 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.21640322 |
46 | ABC transporters_Homo sapiens_hsa02010 | 1.20904277 |
47 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.14494090 |
48 | Carbon metabolism_Homo sapiens_hsa01200 | 1.12642157 |
49 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.01742565 |
50 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.00651201 |
51 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.98046049 |
52 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.97101067 |
53 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.95775820 |
54 | Sulfur relay system_Homo sapiens_hsa04122 | 0.94714998 |
55 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.88881703 |
56 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.83207099 |
57 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.82894376 |
58 | Lysine degradation_Homo sapiens_hsa00310 | 0.81595511 |
59 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.76832388 |
60 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.69628298 |
61 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.66486610 |
62 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.65536790 |
63 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.55736194 |
64 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.53535326 |
65 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.46550949 |
66 | * Metabolic pathways_Homo sapiens_hsa01100 | 0.45898337 |
67 | * Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.45173392 |
68 | Prion diseases_Homo sapiens_hsa05020 | 0.43625506 |
69 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.41184138 |
70 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.24995154 |
71 | Galactose metabolism_Homo sapiens_hsa00052 | 0.24678105 |
72 | Pertussis_Homo sapiens_hsa05133 | 0.23956513 |
73 | Insulin resistance_Homo sapiens_hsa04931 | 0.23039228 |
74 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.22341686 |
75 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.22110930 |
76 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.21921310 |
77 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.20373112 |
78 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.16213731 |
79 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.10099717 |
80 | Other glycan degradation_Homo sapiens_hsa00511 | 0.05892452 |
81 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.01776169 |
82 | Lysosome_Homo sapiens_hsa04142 | -0.2713978 |
83 | Ether lipid metabolism_Homo sapiens_hsa00565 | -0.2443269 |
84 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | -0.2365740 |
85 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | -0.2312277 |
86 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | -0.2250238 |
87 | Amoebiasis_Homo sapiens_hsa05146 | -0.2183704 |
88 | Circadian rhythm_Homo sapiens_hsa04710 | -0.1982762 |
89 | Renin-angiotensin system_Homo sapiens_hsa04614 | -0.1976574 |
90 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | -0.1896663 |
91 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | -0.1891079 |
92 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | -0.1861761 |
93 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | -0.1822990 |
94 | Hepatitis C_Homo sapiens_hsa05160 | -0.1774645 |
95 | Type II diabetes mellitus_Homo sapiens_hsa04930 | -0.1758886 |
96 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | -0.1654881 |
97 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | -0.1642705 |
98 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | -0.1507955 |
99 | African trypanosomiasis_Homo sapiens_hsa05143 | -0.1468474 |
100 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | -0.1233046 |
101 | Regulation of autophagy_Homo sapiens_hsa04140 | -0.1204097 |
102 | Sphingolipid metabolism_Homo sapiens_hsa00600 | -0.1153207 |
103 | Mineral absorption_Homo sapiens_hsa04978 | -0.1080114 |
104 | Insulin signaling pathway_Homo sapiens_hsa04910 | -0.1028549 |
105 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | -0.0811766 |
106 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | -0.0808859 |
107 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | -0.0661048 |
108 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | -0.0507153 |
109 | Serotonergic synapse_Homo sapiens_hsa04726 | -0.0343266 |