BABAM1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein maturation by protein folding (GO:0022417)5.57558069
2viral transcription (GO:0019083)5.50858992
3translational termination (GO:0006415)5.27451240
4translational elongation (GO:0006414)4.94956866
5ribosomal small subunit assembly (GO:0000028)4.85776126
6establishment of viral latency (GO:0019043)4.65171005
7establishment of integrated proviral latency (GO:0075713)4.58806742
8SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.57988149
9protein targeting to ER (GO:0045047)4.45483995
10cotranslational protein targeting to membrane (GO:0006613)4.43413802
11ribosomal small subunit biogenesis (GO:0042274)4.39381207
12DNA deamination (GO:0045006)4.30362541
13negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)4.20326972
14protein localization to endoplasmic reticulum (GO:0070972)4.20044680
15establishment of protein localization to endoplasmic reticulum (GO:0072599)4.19450749
16folic acid-containing compound biosynthetic process (GO:0009396)4.18847489
17translational initiation (GO:0006413)4.17923433
18viral life cycle (GO:0019058)4.10000636
19cellular protein complex disassembly (GO:0043624)4.09812498
20nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.05468450
21GDP-mannose metabolic process (GO:0019673)3.93324834
22regulation of mitochondrial translation (GO:0070129)3.87418020
23ribosomal large subunit biogenesis (GO:0042273)3.86605256
24maturation of SSU-rRNA (GO:0030490)3.84243543
25positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.77708087
26DNA strand elongation involved in DNA replication (GO:0006271)3.75606660
27nuclear envelope reassembly (GO:0031468)3.74177579
28mitotic nuclear envelope reassembly (GO:0007084)3.74177579
29glycine metabolic process (GO:0006544)3.73895856
30regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.73142940
31anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.69113077
32Golgi transport vesicle coating (GO:0048200)3.68863254
33COPI coating of Golgi vesicle (GO:0048205)3.68863254
34protein complex disassembly (GO:0043241)3.68264607
35pteridine-containing compound biosynthetic process (GO:0042559)3.62484580
36telomere maintenance via semi-conservative replication (GO:0032201)3.58309881
37regulation of cellular amino acid metabolic process (GO:0006521)3.56457989
38peptidyl-arginine omega-N-methylation (GO:0035247)3.55727263
39DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.51858303
40macromolecular complex disassembly (GO:0032984)3.47058042
41DNA strand elongation (GO:0022616)3.46300918
42intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.45679312
43signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.45679312
44translation (GO:0006412)3.45254490
45formation of translation preinitiation complex (GO:0001731)3.44478301
46lysine metabolic process (GO:0006553)3.42806211
47lysine catabolic process (GO:0006554)3.42806211
48signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.40839440
49signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.40839440
50signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.40839440
51signal transduction involved in DNA damage checkpoint (GO:0072422)3.40076897
52signal transduction involved in DNA integrity checkpoint (GO:0072401)3.40076897
53metallo-sulfur cluster assembly (GO:0031163)3.38672285
54iron-sulfur cluster assembly (GO:0016226)3.38672285
55positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.37621553
56protoporphyrinogen IX biosynthetic process (GO:0006782)3.35571952
57proteasome assembly (GO:0043248)3.35435452
58signal transduction involved in cell cycle checkpoint (GO:0072395)3.32769472
59serine family amino acid biosynthetic process (GO:0009070)3.28445417
60protein targeting to mitochondrion (GO:0006626)3.25321121
61positive regulation of ligase activity (GO:0051351)3.24760469
62erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.23857802
63L-phenylalanine metabolic process (GO:0006558)3.23857802
64pentose-phosphate shunt (GO:0006098)3.18654170
65heme biosynthetic process (GO:0006783)3.18612199
66antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.17646982
67nucleobase-containing small molecule interconversion (GO:0015949)3.17540009
68nucleoside salvage (GO:0043174)3.15504339
69oxidative phosphorylation (GO:0006119)3.15346874
70protoporphyrinogen IX metabolic process (GO:0046501)3.13373117
71regulation of ubiquitin-protein transferase activity (GO:0051438)3.12334184
72oxaloacetate metabolic process (GO:0006107)3.10610638
73histone arginine methylation (GO:0034969)3.10010779
74aldehyde catabolic process (GO:0046185)3.09358261
75deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.09343522
76folic acid metabolic process (GO:0046655)3.05292171
77ribonucleoprotein complex biogenesis (GO:0022613)3.04516840
78tetrahydrofolate metabolic process (GO:0046653)3.03934638
79deoxyribonucleoside triphosphate metabolic process (GO:0009200)3.03653768
80regulation of ligase activity (GO:0051340)3.02577906
81tricarboxylic acid cycle (GO:0006099)3.00533677
82pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130)2.99160263
83establishment of protein localization to mitochondrion (GO:0072655)2.98702710
84protein targeting to membrane (GO:0006612)2.96821799
85serine family amino acid metabolic process (GO:0009069)2.95979729
86UV protection (GO:0009650)2.95252468
87DNA replication initiation (GO:0006270)2.95232107
88deoxyribose phosphate biosynthetic process (GO:0046385)2.94831996
892-deoxyribonucleotide biosynthetic process (GO:0009265)2.94831996
90purine deoxyribonucleotide catabolic process (GO:0009155)2.93784588
91negative regulation of release of cytochrome c from mitochondria (GO:0090201)2.92551914
92regulation of protein heterodimerization activity (GO:0043497)2.92231681
93pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.91601452
94nuclear-transcribed mRNA catabolic process (GO:0000956)2.88854845
95heme metabolic process (GO:0042168)2.88465034
96spliceosomal snRNP assembly (GO:0000387)2.88080786
97maternal placenta development (GO:0001893)2.88023942
98proline biosynthetic process (GO:0006561)2.87711804
99glyoxylate metabolic process (GO:0046487)2.86817386
100pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.86169538
101nucleobase biosynthetic process (GO:0046112)2.85314145
102deoxyribose phosphate catabolic process (GO:0046386)2.84845499
103guanosine-containing compound biosynthetic process (GO:1901070)2.84790218
104ribosome assembly (GO:0042255)2.84687468
105chaperone-mediated protein transport (GO:0072321)2.83981654
106telomere maintenance via recombination (GO:0000722)2.83799710
107deoxyribonucleotide catabolic process (GO:0009264)2.83524115
108deoxyribonucleotide biosynthetic process (GO:0009263)2.82670737
109pentose metabolic process (GO:0019321)2.82304904
110mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.81778990
111positive regulation of cell cycle arrest (GO:0071158)2.80082595
1122-deoxyribonucleotide metabolic process (GO:0009394)2.79942359
113pyrimidine nucleoside monophosphate metabolic process (GO:0009129)2.78852835
114protein localization to mitochondrion (GO:0070585)2.77754263
115base-excision repair (GO:0006284)2.76326315
116deoxyribose phosphate metabolic process (GO:0019692)2.75919999
117negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.75259676
118purine deoxyribonucleotide metabolic process (GO:0009151)2.74882776
119transcription-coupled nucleotide-excision repair (GO:0006283)2.74511154
120lipopolysaccharide biosynthetic process (GO:0009103)2.73872679
121glucose catabolic process (GO:0006007)2.73591298
122regulation of translational termination (GO:0006449)2.73172577
123de novo posttranslational protein folding (GO:0051084)2.72822491
124nucleotide salvage (GO:0043173)2.72201317
125mRNA catabolic process (GO:0006402)2.71912986
126de novo protein folding (GO:0006458)2.71579634
127ncRNA 3-end processing (GO:0043628)2.70721137
128regulation of mitochondrial membrane potential (GO:0051881)2.70302108
129negative regulation of RNA splicing (GO:0033119)2.70231603
130Arp2/3 complex-mediated actin nucleation (GO:0034314)2.70063707
131nucleoside diphosphate biosynthetic process (GO:0009133)2.69356339
132peptidyl-arginine N-methylation (GO:0035246)2.69187304
133peptidyl-arginine methylation (GO:0018216)2.69187304
134pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173)2.68119865
135UMP biosynthetic process (GO:0006222)2.68119865
136pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174)2.68119865
137UMP metabolic process (GO:0046049)2.68119865
138base-excision repair, AP site formation (GO:0006285)2.68103983
139L-serine metabolic process (GO:0006563)2.67825895
140DNA unwinding involved in DNA replication (GO:0006268)2.67715825
141regulation of cellular amine metabolic process (GO:0033238)2.67039384
142mitotic recombination (GO:0006312)2.66800142
143NADPH regeneration (GO:0006740)2.66378395
144IMP biosynthetic process (GO:0006188)2.65449892
145cullin deneddylation (GO:0010388)2.65222951
146RNA catabolic process (GO:0006401)2.65070741
147NADH metabolic process (GO:0006734)2.63274877
148pyrimidine nucleoside salvage (GO:0043097)2.63247222
149pyrimidine-containing compound salvage (GO:0008655)2.63247222
150protein deneddylation (GO:0000338)2.61890303
151sulfur amino acid catabolic process (GO:0000098)2.60083255
152negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.59534001
153telomere maintenance via telomere lengthening (GO:0010833)2.59416534
154ATP synthesis coupled proton transport (GO:0015986)2.59053494
155energy coupled proton transport, down electrochemical gradient (GO:0015985)2.59053494
156pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.57754102
157folic acid-containing compound metabolic process (GO:0006760)2.57361694
158valine metabolic process (GO:0006573)2.57206051
159cellular component biogenesis (GO:0044085)2.55904834
160rRNA processing (GO:0006364)2.55771370
161cysteine metabolic process (GO:0006534)2.54925514
162antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.54805586
163porphyrin-containing compound biosynthetic process (GO:0006779)2.54526384
164pyrimidine nucleoside biosynthetic process (GO:0046134)2.53465169
165negative regulation of ligase activity (GO:0051352)2.53339548
166negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.53339548
167ethanol oxidation (GO:0006069)2.52874930

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.38542461
2E2F7_22180533_ChIP-Seq_HELA_Human4.29863328
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.56103066
4ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.82893550
5PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.67462144
6MYC_18358816_ChIP-ChIP_MESCs_Mouse2.60671496
7JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.49972911
8ETS1_20019798_ChIP-Seq_JURKAT_Human2.45284937
9MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.36602598
10NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.35101980
11MYC_19079543_ChIP-ChIP_MESCs_Mouse2.33609714
12GABP_17652178_ChIP-ChIP_JURKAT_Human2.32230765
13KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.25314593
14XRN2_22483619_ChIP-Seq_HELA_Human2.19885535
15CREB1_15753290_ChIP-ChIP_HEK293T_Human2.19399622
16MYC_19030024_ChIP-ChIP_MESCs_Mouse2.15652947
17FOXM1_23109430_ChIP-Seq_U2OS_Human2.13860959
18EST1_17652178_ChIP-ChIP_JURKAT_Human2.13261658
19MYC_22102868_ChIP-Seq_BL_Human2.05377363
20HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.02509207
21* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.91497955
22TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.87449667
23VDR_21846776_ChIP-Seq_THP-1_Human1.86170278
24SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.85026183
25DCP1A_22483619_ChIP-Seq_HELA_Human1.84855835
26E2F1_18555785_ChIP-Seq_MESCs_Mouse1.82090960
27PPARA_22158963_ChIP-Seq_LIVER_Mouse1.81358702
28E2F4_17652178_ChIP-ChIP_JURKAT_Human1.80171991
29ELF1_17652178_ChIP-ChIP_JURKAT_Human1.79205967
30SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.78733462
31RXR_22158963_ChIP-Seq_LIVER_Mouse1.75134775
32TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.73095827
33GABP_19822575_ChIP-Seq_HepG2_Human1.68901171
34CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.65201189
35NELFA_20434984_ChIP-Seq_ESCs_Mouse1.62392140
36SRY_22984422_ChIP-ChIP_TESTIS_Rat1.62370901
37EGR1_19374776_ChIP-ChIP_THP-1_Human1.61142324
38YY1_21170310_ChIP-Seq_MESCs_Mouse1.56872803
39FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.56689635
40VDR_23849224_ChIP-Seq_CD4+_Human1.56489262
41THAP11_20581084_ChIP-Seq_MESCs_Mouse1.54239706
42FOXP3_21729870_ChIP-Seq_TREG_Human1.53971962
43TTF2_22483619_ChIP-Seq_HELA_Human1.47938973
44LXR_22292898_ChIP-Seq_THP-1_Human1.46932489
45ZFX_18555785_ChIP-Seq_MESCs_Mouse1.46501830
46STAT3_1855785_ChIP-Seq_MESCs_Mouse1.45240713
47CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.45106446
48CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.43479851
49CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.35438911
50HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.34803723
51DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.32180615
52CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.31401091
53CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.29341036
54TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.28060205
55ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.27663317
56ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.24998098
57SRF_21415370_ChIP-Seq_HL-1_Mouse1.24576070
58POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.24116871
59KLF4_18555785_ChIP-Seq_MESCs_Mouse1.23475950
60SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.23105190
61HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.22394097
62TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.22348869
63HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.21930913
64ELK3_25401928_ChIP-Seq_HUVEC_Human1.21543567
65RARG_19884340_ChIP-ChIP_MEFs_Mouse1.20780451
66KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.19622854
67NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.18783660
68CIITA_25753668_ChIP-Seq_RAJI_Human1.17859938
69MYCN_18555785_ChIP-Seq_MESCs_Mouse1.17175592
70CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.16850323
71ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.16258523
72KDM5A_27292631_Chip-Seq_BREAST_Human1.15513020
73RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.15383077
74P68_20966046_ChIP-Seq_HELA_Human1.15334158
75BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.14956590
76E2F1_21310950_ChIP-Seq_MCF-7_Human1.13144757
77CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.12444739
78TBX5_21415370_ChIP-Seq_HL-1_Mouse1.12369749
79NANOG_18555785_ChIP-Seq_MESCs_Mouse1.11792013
80ERG_20887958_ChIP-Seq_HPC-7_Mouse1.11606127
81TET1_21451524_ChIP-Seq_MESCs_Mouse1.11411198
82ELF1_20517297_ChIP-Seq_JURKAT_Human1.10996829
83PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.10583440
84POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.09644006
85PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.09213821
86GATA1_22383799_ChIP-Seq_G1ME_Mouse1.09113732
87SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.08597869
88BCL6_27268052_Chip-Seq_Bcells_Human1.08273823
89ZNF263_19887448_ChIP-Seq_K562_Human1.08159671
90TFEB_21752829_ChIP-Seq_HELA_Human1.07279699
91* FOXP1_21924763_ChIP-Seq_HESCs_Human1.06989348
92CTCF_18555785_ChIP-Seq_MESCs_Mouse1.06759020
93MAF_26560356_Chip-Seq_TH2_Human1.06409951
94CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.05995241
95MAF_26560356_Chip-Seq_TH1_Human1.05959986
96NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.05615281
97YY1_22570637_ChIP-Seq_MALME-3M_Human1.05361398
98YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.04677559
99OCT4_18692474_ChIP-Seq_MEFs_Mouse1.04591804
100DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.04390465
101SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.03716506
102UTX_26944678_Chip-Seq_JUKART_Human1.03370249
103THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.02814365
104HOXB4_20404135_ChIP-ChIP_EML_Mouse1.02479620
105ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.02175366
106E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.01018164
107BP1_19119308_ChIP-ChIP_Hs578T_Human0.99922962
108RACK7_27058665_Chip-Seq_MCF-7_Human0.99715082
109ATF3_27146783_Chip-Seq_COLON_Human0.99536305
110CTCF_26484167_Chip-Seq_Bcells_Mouse0.99037656
111GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.98882465
112CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.98175477
113BCOR_27268052_Chip-Seq_Bcells_Human0.97525277
114FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.97174702
115MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.97052799

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005360_urolithiasis4.49834505
2MP0002139_abnormal_hepatobiliary_system4.16979659
3MP0005451_abnormal_body_composition3.53840917
4MP0005058_abnormal_lysosome_morphology3.48515756
5MP0003693_abnormal_embryo_hatching3.15616700
6MP0008260_abnormal_autophagy3.15540806
7MP0009379_abnormal_foot_pigmentation2.94093312
8MP0003806_abnormal_nucleotide_metabolis2.78151885
9MP0009840_abnormal_foam_cell2.72919339
10MP0005085_abnormal_gallbladder_physiolo2.63190613
11MP0005365_abnormal_bile_salt2.60259119
12MP0005083_abnormal_biliary_tract2.52382520
13MP0004957_abnormal_blastocyst_morpholog2.44196438
14MP0006036_abnormal_mitochondrial_physio2.37889846
15MP0003705_abnormal_hypodermis_morpholog2.28078467
16MP0008875_abnormal_xenobiotic_pharmacok2.08757169
17MP0003186_abnormal_redox_activity2.06825428
18MP0005332_abnormal_amino_acid2.01362902
19MP0000751_myopathy1.94356647
20MP0003656_abnormal_erythrocyte_physiolo1.91345948
21MP0005319_abnormal_enzyme/_coenzyme1.88647599
22MP0003111_abnormal_nucleus_morphology1.87545078
23MP0004233_abnormal_muscle_weight1.86332715
24MP0009333_abnormal_splenocyte_physiolog1.83626860
25MP0003436_decreased_susceptibility_to1.71703102
26MP0003077_abnormal_cell_cycle1.69052595
27MP0010094_abnormal_chromosome_stability1.60928320
28MP0009278_abnormal_bone_marrow1.57268882
29MP0003191_abnormal_cellular_cholesterol1.57061414
30MP0000685_abnormal_immune_system1.55277441
31MP0009643_abnormal_urine_homeostasis1.50509513
32MP0008932_abnormal_embryonic_tissue1.50354319
33MP0003303_peritoneal_inflammation1.48002805
34MP0000747_muscle_weakness1.47717885
35MP0005165_increased_susceptibility_to1.47628520
36MP0003646_muscle_fatigue1.45319598
37MP0003075_altered_response_to1.44850027
38MP0005501_abnormal_skin_physiology1.44357201
39MP0005636_abnormal_mineral_homeostasis1.43507493
40MP0010329_abnormal_lipoprotein_level1.43346256
41MP0006035_abnormal_mitochondrial_morpho1.39647467
42MP0000609_abnormal_liver_physiology1.37384532
43MP0000490_abnormal_crypts_of1.37192651
44MP0003300_gastrointestinal_ulcer1.34986984
45MP0000358_abnormal_cell_content/1.34539853
46MP0000343_altered_response_to1.31975258
47MP0000598_abnormal_liver_morphology1.29891529
48MP0000858_altered_metastatic_potential1.29701394
49MP0005584_abnormal_enzyme/coenzyme_acti1.27867553
50MP0001661_extended_life_span1.26474280
51MP0003329_amyloid_beta_deposits1.25240925
52MP0008469_abnormal_protein_level1.24819484
53MP0008007_abnormal_cellular_replicative1.19512113
54MP0002396_abnormal_hematopoietic_system1.19064333
55MP0001730_embryonic_growth_arrest1.18207589
56MP0009697_abnormal_copulation1.16873405
57MP0003252_abnormal_bile_duct1.16150187
58MP0000759_abnormal_skeletal_muscle1.15682948
59MP0000689_abnormal_spleen_morphology1.13269371
60MP0001545_abnormal_hematopoietic_system1.11749269
61MP0005397_hematopoietic_system_phenotyp1.11749269
62MP0005330_cardiomyopathy1.11458256
63MP0002019_abnormal_tumor_incidence1.10674410
64MP0002722_abnormal_immune_system1.10380566
65MP0001756_abnormal_urination1.09975559
66MP0000750_abnormal_muscle_regeneration1.09680388
67MP0003221_abnormal_cardiomyocyte_apopto1.07805519
68MP0003763_abnormal_thymus_physiology1.06874545
69MP0002398_abnormal_bone_marrow1.06494124
70MP0000313_abnormal_cell_death1.05605580
71MP0000749_muscle_degeneration1.04968873
72MP0004185_abnormal_adipocyte_glucose1.03338350
73MP0005384_cellular_phenotype1.03207738
74MP0002138_abnormal_hepatobiliary_system1.01733467
75MP0002080_prenatal_lethality0.99993863
76MP0005023_abnormal_wound_healing0.98619710
77MP0001663_abnormal_digestive_system0.98166805
78MP0001764_abnormal_homeostasis0.97984320
79MP0003195_calcinosis0.96531039
80MP0009785_altered_susceptibility_to0.94938789
81MP0002269_muscular_atrophy0.94899684
82MP0001853_heart_inflammation0.94200940
83MP0002148_abnormal_hypersensitivity_rea0.93988680
84MP0001727_abnormal_embryo_implantation0.93940097
85MP0002429_abnormal_blood_cell0.93817662
86MP0003718_maternal_effect0.93088501
87MP0000350_abnormal_cell_proliferation0.92434586
88MP0005621_abnormal_cell_physiology0.91927481
89MP0003123_paternal_imprinting0.91919698
90MP0000604_amyloidosis0.91520604
91MP0004019_abnormal_vitamin_homeostasis0.91303295
92MP0004147_increased_porphyrin_level0.89487753
93MP0003172_abnormal_lysosome_physiology0.89169730
94MP0000703_abnormal_thymus_morphology0.88478222
95MP0001666_abnormal_nutrient_absorption0.88209908
96MP0005025_abnormal_response_to0.87615416
97MP0002420_abnormal_adaptive_immunity0.87399179
98MP0001819_abnormal_immune_cell0.87397945
99MP0001243_abnormal_dermal_layer0.86860518
100MP0005075_abnormal_melanosome_morpholog0.86359821
101MP0009672_abnormal_birth_weight0.86122821
102MP0002419_abnormal_innate_immunity0.85792271
103MP0002132_abnormal_respiratory_system0.84368569
104MP0010352_gastrointestinal_tract_polyps0.84368247
105MP0010030_abnormal_orbit_morphology0.84153267
106MP0001697_abnormal_embryo_size0.83844885
107MP0004087_abnormal_muscle_fiber0.83033060
108MP0006054_spinal_hemorrhage0.82520773
109MP0001835_abnormal_antigen_presentation0.82450408
110MP0001800_abnormal_humoral_immune0.82122182
111MP0002332_abnormal_exercise_endurance0.81374410
112MP0010155_abnormal_intestine_physiology0.80173183
113MP0001845_abnormal_inflammatory_respons0.79413602
114MP0000003_abnormal_adipose_tissue0.78917687
115MP0005670_abnormal_white_adipose0.78830605
116MP0003566_abnormal_cell_adhesion0.78768425
117MP0003786_premature_aging0.78696456
118MP0001849_ear_inflammation0.78558922
119MP0010307_abnormal_tumor_latency0.78384403
120MP0002136_abnormal_kidney_physiology0.77425722
121MP0001873_stomach_inflammation0.76882813
122MP0000716_abnormal_immune_system0.76859118
123MP0005000_abnormal_immune_tolerance0.76133562
124MP0005464_abnormal_platelet_physiology0.75942994
125MP0005266_abnormal_metabolism0.75566638
126MP0002970_abnormal_white_adipose0.74738997
127MP0002837_dystrophic_cardiac_calcinosis0.74281323
128MP0009053_abnormal_anal_canal0.73479598
129MP0004808_abnormal_hematopoietic_stem0.73207170
130MP0002106_abnormal_muscle_physiology0.72928232
131MP0000678_abnormal_parathyroid_gland0.72814505
132MP0001905_abnormal_dopamine_level0.72790593
133MP0003724_increased_susceptibility_to0.72685094
134MP0009642_abnormal_blood_homeostasis0.71958653
135MP0002723_abnormal_immune_serum0.71431127
136MP0000477_abnormal_intestine_morphology0.69738263
137MP0008058_abnormal_DNA_repair0.69672485
138MP0009763_increased_sensitivity_to0.68299160
139MP0005380_embryogenesis_phenotype0.67590200
140MP0001672_abnormal_embryogenesis/_devel0.67590200
141MP0008873_increased_physiological_sensi0.67562899
142MP0002877_abnormal_melanocyte_morpholog0.66601367

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)3.80114884
2Abnormality of aromatic amino acid family metabolism (HP:0004338)3.79592304
3Abnormal number of erythroid precursors (HP:0012131)3.67226654
4Reticulocytopenia (HP:0001896)3.66620558
5Abnormality of monocarboxylic acid metabolism (HP:0010996)3.60091539
6Vertebral compression fractures (HP:0002953)3.55017159
7Multiple enchondromatosis (HP:0005701)3.52227665
8Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.38139485
9Decreased activity of mitochondrial respiratory chain (HP:0008972)3.38139485
10Hepatic necrosis (HP:0002605)3.30274361
11Hepatocellular necrosis (HP:0001404)3.17027714
12Abnormality of pyrimidine metabolism (HP:0004353)3.15777583
13Abnormality of glycolysis (HP:0004366)3.01078175
14Microvesicular hepatic steatosis (HP:0001414)2.99965651
15Macrocytic anemia (HP:0001972)2.93299758
16Rough bone trabeculation (HP:0100670)2.89864533
17Centrally nucleated skeletal muscle fibers (HP:0003687)2.88529722
18Deep venous thrombosis (HP:0002625)2.86342594
19Increased serum pyruvate (HP:0003542)2.85411882
20Hyperammonemia (HP:0001987)2.81663545
21Abnormality of the heme biosynthetic pathway (HP:0010472)2.76983866
22Oral leukoplakia (HP:0002745)2.75292188
23Cholecystitis (HP:0001082)2.74781909
24Abnormal gallbladder physiology (HP:0012438)2.74781909
25Hypobetalipoproteinemia (HP:0003563)2.71744536
26Pallor (HP:0000980)2.70056777
27Nausea (HP:0002018)2.68631799
28Progressive muscle weakness (HP:0003323)2.68208315
29Hyperglycinuria (HP:0003108)2.67430278
30Myopathic facies (HP:0002058)2.64763893
31Abnormality of reticulocytes (HP:0004312)2.63151429
32Cerebral hypomyelination (HP:0006808)2.59296559
33Acute encephalopathy (HP:0006846)2.59162169
34Type I transferrin isoform profile (HP:0003642)2.59098071
35Late onset (HP:0003584)2.58001960
36Mitochondrial inheritance (HP:0001427)2.57676212
37Hepatosplenomegaly (HP:0001433)2.57606194
38Abnormal hemoglobin (HP:0011902)2.55859401
39Xanthomatosis (HP:0000991)2.51012921
40Cerebral edema (HP:0002181)2.49694630
41Angiofibromas (HP:0010615)2.49658987
42Adenoma sebaceum (HP:0009720)2.49658987
43Ragged-red muscle fibers (HP:0003200)2.49573542
44Trismus (HP:0000211)2.49043556
45Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.48324810
46Increased serum ferritin (HP:0003281)2.48132992
47Increased muscle lipid content (HP:0009058)2.47868391
48Ketosis (HP:0001946)2.47849820
49Distal lower limb muscle weakness (HP:0009053)2.46737486
50Abnormality of fatty-acid metabolism (HP:0004359)2.45549788
51Increased serum lactate (HP:0002151)2.44937545
52Microretrognathia (HP:0000308)2.44490966
53Abnormal mitochondria in muscle tissue (HP:0008316)2.44457180
54Increased CSF lactate (HP:0002490)2.43436260
55Hypertensive crisis (HP:0100735)2.40363402
56Testicular atrophy (HP:0000029)2.39207003
57Hyperbilirubinemia (HP:0002904)2.38769249
58Reduced antithrombin III activity (HP:0001976)2.38011756
59Increased intramyocellular lipid droplets (HP:0012240)2.36172971
60Hypokinesia (HP:0002375)2.35552018
61Lactic acidosis (HP:0003128)2.32488686
62Aplasia/Hypoplasia of the sacrum (HP:0008517)2.30091070
63Abnormality of glutamine family amino acid metabolism (HP:0010902)2.29779963
64Progressive macrocephaly (HP:0004481)2.29461463
65Entropion (HP:0000621)2.27905811
66Intrahepatic cholestasis (HP:0001406)2.27671016
67Hyperglycinemia (HP:0002154)2.26627069
68Rhabdomyolysis (HP:0003201)2.26460171
69Muscle stiffness (HP:0003552)2.26364444
70Thrombocytosis (HP:0001894)2.26198273
71Acute necrotizing encephalopathy (HP:0006965)2.25349816
72Lethargy (HP:0001254)2.25248701
73Abnormality of serine family amino acid metabolism (HP:0010894)2.23459903
74Abnormality of glycine metabolism (HP:0010895)2.23459903
75Difficulty climbing stairs (HP:0003551)2.22849560
76Abnormality of liposaccharide metabolism (HP:0010968)2.21285429
77Abnormality of glycosphingolipid metabolism (HP:0004343)2.21285429
78Abnormality of glycolipid metabolism (HP:0010969)2.21285429
79Increased connective tissue (HP:0009025)2.20819648
80Nemaline bodies (HP:0003798)2.20586911
81Opisthotonus (HP:0002179)2.19629558
82Abnormality of nucleobase metabolism (HP:0010932)2.19225757
83Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.19002748
84Abnormal protein N-linked glycosylation (HP:0012347)2.19002748
85Abnormal protein glycosylation (HP:0012346)2.19002748
86Abnormal glycosylation (HP:0012345)2.19002748
87Conjunctival hamartoma (HP:0100780)2.18770922
88Abnormality of dicarboxylic acid metabolism (HP:0010995)2.18091874
89Dicarboxylic aciduria (HP:0003215)2.18091874
90Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.17275737
91Respiratory failure (HP:0002878)2.15558748
92Renal Fanconi syndrome (HP:0001994)2.15501183
93Ketoacidosis (HP:0001993)2.13503186
94Delusions (HP:0000746)2.12581928
95Neonatal onset (HP:0003623)2.11990307
96Aplastic anemia (HP:0001915)2.11020616
97Cholelithiasis (HP:0001081)2.10547674
98Abnormality of the Achilles tendon (HP:0005109)2.10319140
99Abnormal cartilage morphology (HP:0002763)2.08349093
100Neoplasm of head and neck (HP:0012288)2.08133543
101Esophageal neoplasm (HP:0100751)2.08133543
102Distal lower limb amyotrophy (HP:0008944)2.07688444
103Broad distal phalanx of finger (HP:0009836)2.06516143
104Abnormal platelet function (HP:0011869)2.06427202
105Impaired platelet aggregation (HP:0003540)2.06427202
106Abnormal trabecular bone morphology (HP:0100671)2.06262067
107Spastic diplegia (HP:0001264)2.06244603
108Cerebral palsy (HP:0100021)2.06031473
109Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.05128362
110Reticulocytosis (HP:0001923)2.04950045
111Abnormality of iron homeostasis (HP:0011031)2.03703874
112Pancytopenia (HP:0001876)2.03163355
113CNS demyelination (HP:0007305)2.02720230
114Reduced subcutaneous adipose tissue (HP:0003758)2.02652369
115Myoglobinuria (HP:0002913)2.02518886
116Abnormality of transition element cation homeostasis (HP:0011030)2.02428490
117Hypoglycemic coma (HP:0001325)2.00195643
118Emotional lability (HP:0000712)1.99942335
119Verrucae (HP:0200043)1.99702532
120Papilloma (HP:0012740)1.99702532
121Gout (HP:0001997)1.99075090
122Petechiae (HP:0000967)1.98450351
123Microcytic anemia (HP:0001935)1.97844768
124Increased hepatocellular lipid droplets (HP:0006565)1.97621299
125Exercise intolerance (HP:0003546)1.97097810
126Fatigue (HP:0012378)1.95949005
127Generalized aminoaciduria (HP:0002909)1.95414855
128Hyperphosphaturia (HP:0003109)1.94511956
129Abnormality of lateral ventricle (HP:0030047)1.94054553
130Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)1.93594039
131Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.93251117
132Abnormality of the gallbladder (HP:0005264)1.92342989
133Elevated erythrocyte sedimentation rate (HP:0003565)1.91065389
134Abnormality of the anterior horn cell (HP:0006802)1.90655052
135Degeneration of anterior horn cells (HP:0002398)1.90655052
136Metabolic acidosis (HP:0001942)1.89451017
137Muscle fiber inclusion bodies (HP:0100299)1.87718569
138Exertional dyspnea (HP:0002875)1.87589893
139Fasciculations (HP:0002380)1.85789442
140Achilles tendon contracture (HP:0001771)1.85652264
141Secondary amenorrhea (HP:0000869)1.85135533
142Shoulder girdle muscle weakness (HP:0003547)1.83689483
143Abnormal gallbladder morphology (HP:0012437)1.82731952
144Multiple lipomas (HP:0001012)1.81901625
145Spastic paraparesis (HP:0002313)1.81679797
146Lipid accumulation in hepatocytes (HP:0006561)1.80894585
147Vomiting (HP:0002013)1.79869251
148Delayed CNS myelination (HP:0002188)1.79596442
149Orthostatic hypotension (HP:0001278)1.78973010
150Retinal dysplasia (HP:0007973)1.77288068
151Progressive microcephaly (HP:0000253)1.76500585
152Upper motor neuron abnormality (HP:0002127)1.74805886
153Dysautonomia (HP:0002459)1.74180304

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK24.27292983
2PKN23.40459880
3NME23.28198705
4ERN13.20496096
5TRIB33.09955192
6MAP3K113.03060990
7TLK12.99202638
8EIF2AK12.98401235
9TESK22.92249965
10BCKDK2.84425309
11BUB12.82096322
12MAP3K102.32053233
13PIM22.25641058
14SMG12.20164567
15KDR2.12230721
16SCYL22.09025177
17TESK12.08914982
18MAP4K11.97928436
19LRRK21.75053715
20EEF2K1.64642273
21WEE11.64609683
22NEK11.60226756
23MAP2K31.58897341
24TAOK21.56712575
25TNK21.56612266
26PBK1.51466717
27BMX1.40715158
28SRPK11.39437937
29BLK1.34641684
30NEK91.34477305
31NEK21.33048414
32PRPF4B1.32509218
33MAP3K81.32094498
34FLT31.30734073
35RPS6KA41.29654445
36STK161.28277936
37GRK61.25635045
38LIMK11.23164529
39PAK41.18613595
40MAPKAPK31.17570031
41TBK11.13851420
42ZAP701.08529827
43CCNB11.08334935
44CDC71.07824034
45BRAF1.05543313
46DYRK31.05164446
47ILK0.98691191
48ABL20.98622686
49CDK190.96182734
50AURKA0.95564490
51EPHA20.94673451
52TAOK10.94415748
53NME10.90860417
54CDK70.90714860
55PDK20.87451120
56MAP3K120.85876121
57MAPK110.83900640
58TGFBR10.83632299
59MAP3K30.82817815
60CSNK1G30.82791090
61STK100.80516544
62DAPK30.79977740
63PRKG20.77227115
64PLK10.76865781
65DYRK1B0.74254447
66MAP2K20.73069661
67VRK10.72927974
68ARAF0.72807878
69PAK60.71771782
70CDK40.71673403
71RPS6KB20.71621748
72PRKD30.70100811
73BTK0.69347106
74CLK10.68232025
75LMTK20.67628830
76EIF2AK30.66459734
77AKT20.64806373
78PIM10.64624833
79MOS0.64266858
80TYK20.61999532
81ICK0.61905496
82CHEK20.60896590
83ATR0.60432288
84CDK140.60272709
85AURKB0.60196503
86TTN0.59245502
87CDK11A0.59094693
88SIK30.58835644
89RAF10.57164398
90PAK10.56669845
91PTK60.55778514
92DAPK10.54218124
93CDK150.52150076
94NTRK10.51978894
95BRSK10.51540565
96PIK3CG0.50965313
97FGFR40.50846470
98CSNK1A1L0.50490845
99SIK10.49720832
100CDK180.49617287
101KIT0.48735263
102CDK80.46468496
103ACVR1B0.45786100
104PRKCI0.45091220
105ALK0.44650742
106CSNK2A10.42914920
107RPS6KA50.40781178
108TSSK60.39655069
109GRK50.39625500
110MAP2K60.39581017
111ZAK0.38212985
112IKBKE0.37797995
113SYK0.36997851
114FES0.36757087
115MATK0.36610075
116JAK20.36431993
117IRAK30.36384447
118TTK0.36036768
119CDK90.35898159
120MAP3K10.35856996
121BRSK20.35170020
122PLK30.34997017
123CHEK10.34400044
124CSNK2A20.33359104
125MAPKAPK20.32879817
126MARK30.32591427
127MAP2K70.32298040
128CAMK2G0.31506917
129MAPK40.29925543
130MYLK0.29718865
131PHKG10.28227770
132PHKG20.28227770
133CSNK1G20.28000072
134PASK0.26865978
135RPS6KA10.26837399
136STK40.26543252
137MAPK150.25928041
138RPS6KC10.25726909

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.19321942
2DNA replication_Homo sapiens_hsa030303.46000070
3Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.75321282
4Proteasome_Homo sapiens_hsa030502.74108508
52-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.42920557
6Mismatch repair_Homo sapiens_hsa034302.38727100
7One carbon pool by folate_Homo sapiens_hsa006702.26693096
8Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.26195705
9Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.25315242
10Sulfur relay system_Homo sapiens_hsa041222.20245267
11Pyrimidine metabolism_Homo sapiens_hsa002402.06665923
12Primary bile acid biosynthesis_Homo sapiens_hsa001202.04377949
13Fatty acid elongation_Homo sapiens_hsa000622.02506628
14Base excision repair_Homo sapiens_hsa034101.99371737
15Carbon metabolism_Homo sapiens_hsa012001.95362146
16Folate biosynthesis_Homo sapiens_hsa007901.95102509
17Spliceosome_Homo sapiens_hsa030401.92401390
18Biosynthesis of amino acids_Homo sapiens_hsa012301.88644651
19Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.85731453
20RNA polymerase_Homo sapiens_hsa030201.84544737
21Parkinsons disease_Homo sapiens_hsa050121.74139447
22Fatty acid degradation_Homo sapiens_hsa000711.61335062
23Pentose and glucuronate interconversions_Homo sapiens_hsa000401.58448897
24Pentose phosphate pathway_Homo sapiens_hsa000301.57710620
25Oxidative phosphorylation_Homo sapiens_hsa001901.56347636
26Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.56152187
27Arginine biosynthesis_Homo sapiens_hsa002201.55553247
28Cyanoamino acid metabolism_Homo sapiens_hsa004601.54030069
29Cysteine and methionine metabolism_Homo sapiens_hsa002701.53805040
30Drug metabolism - other enzymes_Homo sapiens_hsa009831.53231417
31Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.43564376
32Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.42977235
33Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.42778910
34Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.38199067
35Pyruvate metabolism_Homo sapiens_hsa006201.37671328
36Selenocompound metabolism_Homo sapiens_hsa004501.37127840
37Nucleotide excision repair_Homo sapiens_hsa034201.34106797
38Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.32482160
39Tryptophan metabolism_Homo sapiens_hsa003801.28767597
40Huntingtons disease_Homo sapiens_hsa050161.21994310
41Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.20204246
42RNA transport_Homo sapiens_hsa030131.20139317
43Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.17344644
44Homologous recombination_Homo sapiens_hsa034401.16591431
45Vibrio cholerae infection_Homo sapiens_hsa051101.10613785
46Glycosaminoglycan degradation_Homo sapiens_hsa005311.09727363
47Propanoate metabolism_Homo sapiens_hsa006401.09400177
48Peroxisome_Homo sapiens_hsa041461.04664552
49Galactose metabolism_Homo sapiens_hsa000521.02692932
50beta-Alanine metabolism_Homo sapiens_hsa004100.97673736
51Non-homologous end-joining_Homo sapiens_hsa034500.96906392
52Glutathione metabolism_Homo sapiens_hsa004800.93125603
53Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.88453801
54Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.83130458
55Alzheimers disease_Homo sapiens_hsa050100.82275832
56Fanconi anemia pathway_Homo sapiens_hsa034600.82144382
57Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.79653282
58Bladder cancer_Homo sapiens_hsa052190.78820670
59SNARE interactions in vesicular transport_Homo sapiens_hsa041300.78703561
60Cell cycle_Homo sapiens_hsa041100.77679708
61Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.77515205
62Sulfur metabolism_Homo sapiens_hsa009200.76335426
63Thyroid cancer_Homo sapiens_hsa052160.75780002
64Synaptic vesicle cycle_Homo sapiens_hsa047210.75361582
65Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.75241230
66Fructose and mannose metabolism_Homo sapiens_hsa000510.75192533
67Lysosome_Homo sapiens_hsa041420.72988486
68Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.71391832
69Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.70588354
70Butanoate metabolism_Homo sapiens_hsa006500.69704890
71Arginine and proline metabolism_Homo sapiens_hsa003300.69605637
72Primary immunodeficiency_Homo sapiens_hsa053400.68648394
73Starch and sucrose metabolism_Homo sapiens_hsa005000.66511655
74Complement and coagulation cascades_Homo sapiens_hsa046100.66274833
75Phenylalanine metabolism_Homo sapiens_hsa003600.66090617
76Vitamin B6 metabolism_Homo sapiens_hsa007500.65584390
77Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.65509771
78Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.64086925
79Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.62718475
80Purine metabolism_Homo sapiens_hsa002300.62486450
81Chemical carcinogenesis_Homo sapiens_hsa052040.59319229
82Epstein-Barr virus infection_Homo sapiens_hsa051690.57297001
83Fatty acid metabolism_Homo sapiens_hsa012120.55356092
84Metabolic pathways_Homo sapiens_hsa011000.52888215
85Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.52356312
86Protein export_Homo sapiens_hsa030600.52184759
87Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.52027406
88PPAR signaling pathway_Homo sapiens_hsa033200.51827396
89Fat digestion and absorption_Homo sapiens_hsa049750.51562419
90Collecting duct acid secretion_Homo sapiens_hsa049660.51165166
91Nitrogen metabolism_Homo sapiens_hsa009100.49876259
92Tyrosine metabolism_Homo sapiens_hsa003500.49670965
93Antigen processing and presentation_Homo sapiens_hsa046120.49497675
94Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.49036649
95Central carbon metabolism in cancer_Homo sapiens_hsa052300.47368004
96Caffeine metabolism_Homo sapiens_hsa002320.46273448
97p53 signaling pathway_Homo sapiens_hsa041150.45174189
98Oocyte meiosis_Homo sapiens_hsa041140.44687984
99Lysine degradation_Homo sapiens_hsa003100.44543020
100Viral carcinogenesis_Homo sapiens_hsa052030.44451328
101Other glycan degradation_Homo sapiens_hsa005110.44447354
102Acute myeloid leukemia_Homo sapiens_hsa052210.42847871
103Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.42334052
104Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.41519828
105Systemic lupus erythematosus_Homo sapiens_hsa053220.41483964
106Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.41190060
107Shigellosis_Homo sapiens_hsa051310.39866678
108Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.39092408
109Salmonella infection_Homo sapiens_hsa051320.38528172
110Endocytosis_Homo sapiens_hsa041440.38222763
111Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.37679874
112Apoptosis_Homo sapiens_hsa042100.34937697
113RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.34525476
114Chronic myeloid leukemia_Homo sapiens_hsa052200.34409467
115Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.33733776
116Legionellosis_Homo sapiens_hsa051340.33138526
117Cardiac muscle contraction_Homo sapiens_hsa042600.32813651
118HTLV-I infection_Homo sapiens_hsa051660.31800442
119RNA degradation_Homo sapiens_hsa030180.29189448
120Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.28944880
121Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.27900178
122N-Glycan biosynthesis_Homo sapiens_hsa005100.27720858
123Viral myocarditis_Homo sapiens_hsa054160.26985670
124Maturity onset diabetes of the young_Homo sapiens_hsa049500.25708270
125Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.25061200
126Bile secretion_Homo sapiens_hsa049760.23237754
127Herpes simplex infection_Homo sapiens_hsa051680.22551665
128mRNA surveillance pathway_Homo sapiens_hsa030150.21977006
129Pancreatic cancer_Homo sapiens_hsa052120.16203609

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