BAHD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of histone deacetylation (GO:0031065)5.24600886
2daunorubicin metabolic process (GO:0044597)5.00620478
3polyketide metabolic process (GO:0030638)5.00620478
4doxorubicin metabolic process (GO:0044598)5.00620478
5negative regulation of erythrocyte differentiation (GO:0045647)4.99812904
6maintenance of protein location in nucleus (GO:0051457)4.56060395
7histone H4-K12 acetylation (GO:0043983)4.48235761
8positive regulation of protein deacetylation (GO:0090312)4.46693709
9histone H4-K8 acetylation (GO:0043982)4.40687286
10histone H4-K5 acetylation (GO:0043981)4.40687286
11pre-miRNA processing (GO:0031054)4.06233723
123-UTR-mediated mRNA stabilization (GO:0070935)3.95776745
13maternal placenta development (GO:0001893)3.93359390
14negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.88639738
15muscle organ morphogenesis (GO:0048644)3.84516259
16mannose metabolic process (GO:0006013)3.79707483
17regulation of response to osmotic stress (GO:0047484)3.79022409
18histone H4-K16 acetylation (GO:0043984)3.74769748
19somite rostral/caudal axis specification (GO:0032525)3.73539120
20regulation of mammary gland epithelial cell proliferation (GO:0033599)3.69048935
21histone H3-K36 demethylation (GO:0070544)3.66704248
22negative regulation of epidermis development (GO:0045683)3.66396351
23proline transport (GO:0015824)3.61334626
24regulation of MHC class I biosynthetic process (GO:0045343)3.61032483
25hormone catabolic process (GO:0042447)3.60951154
26negative regulation of G2/M transition of mitotic cell cycle (GO:0010972)3.59352886
27apoptotic process involved in morphogenesis (GO:0060561)3.58927701
28ribosomal small subunit biogenesis (GO:0042274)3.57781161
29NLS-bearing protein import into nucleus (GO:0006607)3.55576150
30protein localization to kinetochore (GO:0034501)3.54944317
31adherens junction assembly (GO:0034333)3.53563276
32cell-substrate adherens junction assembly (GO:0007045)3.51885691
33focal adhesion assembly (GO:0048041)3.51885691
34negative regulation of cell size (GO:0045792)3.49148172
35interferon-gamma production (GO:0032609)3.48312476
36negative regulation of telomerase activity (GO:0051974)3.47337920
37regulation of chromatin binding (GO:0035561)3.45380528
38RNA stabilization (GO:0043489)3.44578708
39mRNA stabilization (GO:0048255)3.44578708
40planar cell polarity pathway involved in neural tube closure (GO:0090179)3.38084918
41hypotonic response (GO:0006971)3.37249876
42regulation of histone H3-K27 methylation (GO:0061085)3.33568970
43intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (GO:0070059)3.33400658
44aminoglycoside antibiotic metabolic process (GO:0030647)3.32455566
45cytidine metabolic process (GO:0046087)3.30669088
46cytidine catabolic process (GO:0006216)3.30669088
47cytidine deamination (GO:0009972)3.30669088
48regulation of glucose import in response to insulin stimulus (GO:2001273)3.26829104
49intracellular estrogen receptor signaling pathway (GO:0030520)3.25199701
50Golgi transport vesicle coating (GO:0048200)3.21543313
51COPI coating of Golgi vesicle (GO:0048205)3.21543313
52negative regulation of potassium ion transmembrane transport (GO:1901380)3.19123026
53regulation of hippo signaling (GO:0035330)3.17740215
54negative regulation of cell cycle G2/M phase transition (GO:1902750)3.17675048
55maintenance of protein localization in organelle (GO:0072595)3.16860068
56epithelial cell differentiation involved in prostate gland development (GO:0060742)3.15038136
57retinoic acid receptor signaling pathway (GO:0048384)3.14786005
58establishment of endothelial barrier (GO:0061028)3.14218773
59trophectodermal cell differentiation (GO:0001829)3.11078037
60regulation of telomere maintenance via telomerase (GO:0032210)3.11049401
61negative regulation of viral release from host cell (GO:1902187)3.10139948
62negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147)3.09252059
63regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.08016261
64positive regulation of Cdc42 GTPase activity (GO:0043089)3.05417876
65protein complex localization (GO:0031503)3.00898121
66natural killer cell differentiation (GO:0001779)2.99721209
67branching involved in mammary gland duct morphogenesis (GO:0060444)2.97029114
68nuclear pore complex assembly (GO:0051292)2.95183925
69synaptic vesicle maturation (GO:0016188)2.94223267
70rRNA transcription (GO:0009303)2.92000248
71spliceosomal tri-snRNP complex assembly (GO:0000244)2.91608226
72regulation of RNA export from nucleus (GO:0046831)2.91068027
73mitotic chromosome condensation (GO:0007076)2.90203205
74apoptotic cell clearance (GO:0043277)2.88480217
75positive regulation of macrophage cytokine production (GO:0060907)2.88367787
76regulation of nucleobase-containing compound transport (GO:0032239)2.86732974
77intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (GO:0042771)2.85728874
78regulation of NFAT protein import into nucleus (GO:0051532)2.83377013
79positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.83132565
80response to dietary excess (GO:0002021)2.82884128
81adaptation of signaling pathway (GO:0023058)2.81244412
82positive regulation of Rap GTPase activity (GO:0032854)2.81080225
83positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling2.81072842
84barbed-end actin filament capping (GO:0051016)2.79928781
85retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.79310913
86cellular protein complex localization (GO:0034629)2.78871362
87stress fiber assembly (GO:0043149)2.78260851
88negative regulation of fatty acid transport (GO:2000192)2.77898768
89negative regulation of cell killing (GO:0031342)2.77565625
90negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.77565625
91embryonic process involved in female pregnancy (GO:0060136)2.76477889
92activation of MAPKKK activity (GO:0000185)2.75958599
93tachykinin receptor signaling pathway (GO:0007217)2.75176844
94cytoskeletal anchoring at plasma membrane (GO:0007016)2.74808216
95cell-substrate junction assembly (GO:0007044)2.74608158
96activation of Rac GTPase activity (GO:0032863)2.74024441
97vitamin A metabolic process (GO:0006776)2.73796995
98modulation by symbiont of host cellular process (GO:0044068)2.73784057
99semaphorin-plexin signaling pathway (GO:0071526)2.73017891
100pyrimidine ribonucleoside catabolic process (GO:0046133)2.72241450
101cellular modified amino acid catabolic process (GO:0042219)2.70429123
102cellular response to epidermal growth factor stimulus (GO:0071364)2.69339764
103protein retention in ER lumen (GO:0006621)2.68638656
104positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.67212466
105epithelial cell-cell adhesion (GO:0090136)2.67005497
106primitive streak formation (GO:0090009)2.66191517
107maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.65436650
108negative regulation of bone resorption (GO:0045779)2.65410216
109mitotic sister chromatid segregation (GO:0000070)2.62873242
110viral transcription (GO:0019083)2.61606462
111antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.60111839
112antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.60111839
113pentose-phosphate shunt (GO:0006098)2.59535518
114cellular senescence (GO:0090398)2.58344568
115regulation of early endosome to late endosome transport (GO:2000641)2.57994137
116regulation of intracellular estrogen receptor signaling pathway (GO:0033146)2.57924163
117thymic T cell selection (GO:0045061)2.57601695
118modulation by virus of host process (GO:0019054)2.55384636
119regulation of protein deacetylation (GO:0090311)2.54536357
120response to muramyl dipeptide (GO:0032495)2.54431342
121epoxygenase P450 pathway (GO:0019373)2.54147577
122histone lysine demethylation (GO:0070076)2.54005005
123endoplasmic reticulum calcium ion homeostasis (GO:0032469)2.53153993
124regulation of histone deacetylation (GO:0031063)2.52875178
125antigen processing and presentation of endogenous antigen (GO:0019883)2.50633221
126protein localization to endosome (GO:0036010)2.50030122
127regulation of translational fidelity (GO:0006450)2.48775463
128protein localization to chromosome, centromeric region (GO:0071459)2.47078619
129positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.46192429
130negative regulation of peptidyl-serine phosphorylation (GO:0033137)2.45976317
131pinocytosis (GO:0006907)2.45887589
132cell-cell junction maintenance (GO:0045217)2.45241379
133positive regulation of transcription from RNA polymerase III promoter (GO:0045945)2.44894921
134regulation of gamma-delta T cell differentiation (GO:0045586)2.43058980
135sister chromatid segregation (GO:0000819)2.42389529
136regulation of Rap GTPase activity (GO:0032317)2.40694416
137histone demethylation (GO:0016577)2.40284456
138positive regulation of keratinocyte differentiation (GO:0045618)2.39701879
139nucleosome disassembly (GO:0006337)2.39426805
140protein-DNA complex disassembly (GO:0032986)2.39426805
141embryonic eye morphogenesis (GO:0048048)2.38816254
142nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.38781635
143intestinal epithelial cell development (GO:0060576)2.38752340
144DNA unwinding involved in DNA replication (GO:0006268)2.38344555
145negative regulation of toll-like receptor signaling pathway (GO:0034122)2.37694555
146positive thymic T cell selection (GO:0045059)2.37485893
147cytoplasmic mRNA processing body assembly (GO:0033962)2.36857627
148ear development (GO:0043583)2.36163734
149cellular response to osmotic stress (GO:0071470)2.36119058
150response to laminar fluid shear stress (GO:0034616)2.35800110
151regulation of ARF GTPase activity (GO:0032312)2.34995195
152branching involved in labyrinthine layer morphogenesis (GO:0060670)2.34889761
153nuclear pore organization (GO:0006999)2.34701372
154atrioventricular valve morphogenesis (GO:0003181)2.33782062
155proline biosynthetic process (GO:0006561)2.33136886
156cellular response to virus (GO:0098586)2.33100191
157regulation of cholesterol homeostasis (GO:2000188)2.32714701
158histone H3-K4 methylation (GO:0051568)2.32593257
159negative regulation of glial cell proliferation (GO:0060253)2.32585637
160regulation of macrophage cytokine production (GO:0010935)2.32060010
161L-alpha-amino acid transmembrane transport (GO:1902475)2.31828031
162regulation of extracellular matrix disassembly (GO:0010715)2.31487940
163negative regulation of phagocytosis (GO:0050765)2.31214556
164embryonic placenta development (GO:0001892)2.30494636
165NIK/NF-kappaB signaling (GO:0038061)2.28392474
166regulation of type I interferon-mediated signaling pathway (GO:0060338)2.28345747
167regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway 2.28244926
168positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling2.28244926
169translational termination (GO:0006415)2.28103395
170negative regulation of histone methylation (GO:0031061)2.27657361
171response to peptidoglycan (GO:0032494)2.27320724
172receptor recycling (GO:0001881)2.27142425
173modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.26115420
174positive regulation by organism of defense response of other organism involved in symbiotic interact2.26115420
175modulation by symbiont of host immune response (GO:0052553)2.26115420
176positive regulation by symbiont of host defense response (GO:0052509)2.26115420
177modulation by symbiont of host defense response (GO:0052031)2.26115420
178modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.26115420
179response to epidermal growth factor (GO:0070849)2.26012547
180regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 2.24694130
181activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.24421548

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human4.22205303
2KLF2_18264089_ChIP-ChIP_MESCs_Mouse3.58492349
3KLF5_18264089_ChIP-ChIP_MESCs_Mouse3.58492349
4KLF4_18264089_ChIP-ChIP_MESCs_Mouse3.58492349
5MYC_22102868_ChIP-Seq_BL_Human3.07425269
6NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.92746992
7* KDM2B_26808549_Chip-Seq_SUP-B15_Human2.71078517
8TCF7_22412390_ChIP-Seq_EML_Mouse2.51731646
9EGR1_19374776_ChIP-ChIP_THP-1_Human2.48244445
10* KDM2B_26808549_Chip-Seq_DND41_Human2.23046759
11KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.20007426
12SMAD3_22036565_ChIP-Seq_ESCs_Mouse2.17728217
13ZFP281_18757296_ChIP-ChIP_E14_Mouse2.10129804
14EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.08595854
15ELK3_25401928_ChIP-Seq_HUVEC_Human2.07675479
16* LXR_22292898_ChIP-Seq_THP-1_Human2.01209169
17* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.99800282
18STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.99108115
19* KDM2B_26808549_Chip-Seq_K562_Human1.95137354
20ZFP281_27345836_Chip-Seq_ESCs_Mouse1.94143426
21VDR_21846776_ChIP-Seq_THP-1_Human1.93834793
22ZNF263_19887448_ChIP-Seq_K562_Human1.88425893
23ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.88151432
24EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.87628931
25RARG_19884340_ChIP-ChIP_MEFs_Mouse1.78515586
26THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.78192915
27STAT6_21828071_ChIP-Seq_BEAS2B_Human1.75873545
28HIF1A_21447827_ChIP-Seq_MCF-7_Human1.73457654
29* RACK7_27058665_Chip-Seq_MCF-7_Human1.68998676
30SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.64804338
31ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.63921443
32VDR_24763502_ChIP-Seq_THP-1_Human1.62397129
33POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.62195035
34HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.61320944
35SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.60932721
36CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.59782094
37E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.59496085
38NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.59237753
39PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.53559423
40* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.53292338
41KDM2B_26808549_Chip-Seq_JURKAT_Human1.52718505
42MAF_26560356_Chip-Seq_TH1_Human1.51820264
43* NCOR1_26117541_ChIP-Seq_K562_Human1.51577791
44DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.51402499
45CLOCK_20551151_ChIP-Seq_293T_Human1.50948381
46STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.50658112
47RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.45134002
48* NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.44271755
49P300_27058665_Chip-Seq_ZR-75-30cells_Human1.42842026
50NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.42572263
51NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.42390750
52TET1_21451524_ChIP-Seq_MESCs_Mouse1.41641007
53TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.40964072
54KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.40481403
55UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.40237320
56SA1_27219007_Chip-Seq_ERYTHROID_Human1.38107410
57CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.37362030
58SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.36996490
59KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.35755064
60* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.35594914
61SPI1_23127762_ChIP-Seq_K562_Human1.35387242
62TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.34698071
63KLF4_18555785_ChIP-Seq_MESCs_Mouse1.34398766
64FOXM1_23109430_ChIP-Seq_U2OS_Human1.34077666
65UTX_26944678_Chip-Seq_JUKART_Human1.33458693
66ERG_21242973_ChIP-ChIP_JURKAT_Human1.32817754
67FOXO3_23340844_ChIP-Seq_DLD1_Human1.32402946
68CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.32314213
69* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.30520709
70TP63_19390658_ChIP-ChIP_HaCaT_Human1.29120527
71SRY_22984422_ChIP-ChIP_TESTIS_Rat1.27394070
72IKZF1_21737484_ChIP-ChIP_HCT116_Human1.26423369
73TP53_22127205_ChIP-Seq_IMR90_Human1.26349805
74STAT3_1855785_ChIP-Seq_MESCs_Mouse1.26296845
75RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.26108835
76TCF3_18692474_ChIP-Seq_MESCs_Mouse1.25524803
77E2F7_22180533_ChIP-Seq_HELA_Human1.25328394
78ESR2_21235772_ChIP-Seq_MCF-7_Human1.25072438
79CDX2_20551321_ChIP-Seq_CACO-2_Human1.24946310
80MYC_18555785_ChIP-Seq_MESCs_Mouse1.24757089
81TCF3_18692474_ChIP-Seq_MEFs_Mouse1.24219455
82MYC_19079543_ChIP-ChIP_MESCs_Mouse1.23944838
83SCL_19346495_ChIP-Seq_HPC-7_Human1.23861774
84TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.23294591
85NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.22758706
86TP63_17297297_ChIP-ChIP_HaCaT_Human1.22702782
87ATF3_27146783_Chip-Seq_COLON_Human1.22331667
88TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.22074325
89CREB1_26743006_Chip-Seq_LNCaP_Human1.21517888
90TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.21162873
91SMC4_20622854_ChIP-Seq_HELA_Human1.19923068
92GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.19238969
93VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.19006808
94SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.16675878
95ELF1_20517297_ChIP-Seq_JURKAT_Human1.16258035
96GATA1_22383799_ChIP-Seq_G1ME_Mouse1.15650837
97XRN2_22483619_ChIP-Seq_HELA_Human1.15005936
98CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.14432166
99MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.13729378
100P68_20966046_ChIP-Seq_HELA_Human1.13621272
101* CTCF_27219007_Chip-Seq_ERYTHROID_Human1.13033429
102KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.12473742
103ZFX_18555785_ChIP-Seq_MESCs_Mouse1.11898417
104PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.11377085
105BRD4_27068464_Chip-Seq_AML-cells_Mouse1.10220725
106POU5F1_16518401_ChIP-PET_MESCs_Mouse1.09654124
107DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.08179323
108RUNX1_27514584_Chip-Seq_MCF-7_Human1.07718273
109FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.04860894
110PRDM14_21183938_ChIP-Seq_MESCs_Mouse1.03981030
111RUNX1_22412390_ChIP-Seq_EML_Mouse1.03897834
112MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.02524172
113CTCF_21964334_Chip-Seq_Bcells_Human1.02208037
114NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.01421020
115MYB_26560356_Chip-Seq_TH1_Human1.01123970
116SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.00929244
117TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.00054081
118RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.99648167
119RARB_27405468_Chip-Seq_BRAIN_Mouse0.99100637
120BCOR_27268052_Chip-Seq_Bcells_Human0.98957494
121TCF3_18347094_ChIP-ChIP_MESCs_Mouse0.98405190
122MAF_26560356_Chip-Seq_TH2_Human0.97831827
123NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.97747403
124FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.97693813
125SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse0.97380842
126TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.96456116
127PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.96438984
128* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.96372738
129ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.95296335
130POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.95024324
131HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.94943203
132DNAJC2_21179169_ChIP-ChIP_NT2_Human0.94218615
133MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.94105086
134UBF1/2_26484160_Chip-Seq_HMECs_Human0.93594412
135GATA6_25053715_ChIP-Seq_YYC3_Human0.93459569
136CHD1_26751641_Chip-Seq_LNCaP_Human0.91892544
137TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.91382078
138CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.91265070
139SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.90390252
140MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.89494916

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003705_abnormal_hypodermis_morpholog4.30002574
2MP0004858_abnormal_nervous_system4.11095662
3MP0002254_reproductive_system_inflammat4.03803428
4MP0008961_abnormal_basal_metabolism3.63107546
5MP0004264_abnormal_extraembryonic_tissu3.31733989
6MP0010352_gastrointestinal_tract_polyps3.14863843
7MP0005451_abnormal_body_composition3.06358170
8MP0005058_abnormal_lysosome_morphology2.90209713
9MP0003303_peritoneal_inflammation2.73348672
10MP0005076_abnormal_cell_differentiation2.21536329
11MP0002796_impaired_skin_barrier2.19538317
12MP0003122_maternal_imprinting2.15679181
13MP0003890_abnormal_embryonic-extraembry2.14967181
14MP0005257_abnormal_intraocular_pressure2.14709765
15MP0003300_gastrointestinal_ulcer2.09449501
16MP0001849_ear_inflammation1.98142732
17MP0005394_taste/olfaction_phenotype1.96479849
18MP0005499_abnormal_olfactory_system1.96479849
19MP0005409_darkened_coat_color1.96355897
20MP0003183_abnormal_peptide_metabolism1.94017018
21MP0002877_abnormal_melanocyte_morpholog1.88525562
22MP0004510_myositis1.86579857
23MP0006082_CNS_inflammation1.83999806
24MP0003011_delayed_dark_adaptation1.77064105
25MP0002332_abnormal_exercise_endurance1.75985161
26MP0004381_abnormal_hair_follicle1.72317361
27MP0008260_abnormal_autophagy1.68450938
28MP0000537_abnormal_urethra_morphology1.67627344
29MP0009672_abnormal_birth_weight1.65638096
30MP0001348_abnormal_lacrimal_gland1.65219624
31MP0002909_abnormal_adrenal_gland1.62158489
32MP0002653_abnormal_ependyma_morphology1.61881498
33MP0003763_abnormal_thymus_physiology1.58273859
34MP0009278_abnormal_bone_marrow1.56051770
35MP0004233_abnormal_muscle_weight1.49028632
36MP0002088_abnormal_embryonic_growth/wei1.46602279
37MP0003172_abnormal_lysosome_physiology1.45180121
38MP0003566_abnormal_cell_adhesion1.44683907
39MP0003984_embryonic_growth_retardation1.43783073
40MP0003191_abnormal_cellular_cholesterol1.40056107
41MP0005380_embryogenesis_phenotype1.39192601
42MP0001672_abnormal_embryogenesis/_devel1.39192601
43MP0005501_abnormal_skin_physiology1.36950391
44MP0004185_abnormal_adipocyte_glucose1.35284575
45MP0009333_abnormal_splenocyte_physiolog1.34724600
46MP0003436_decreased_susceptibility_to1.34592282
47MP0002086_abnormal_extraembryonic_tissu1.34574172
48MP0002249_abnormal_larynx_morphology1.33919082
49MP0003121_genomic_imprinting1.31897091
50MP0003091_abnormal_cell_migration1.30142116
51MP0003045_fibrosis1.29686343
52MP0000685_abnormal_immune_system1.28571129
53MP0001790_abnormal_immune_system1.26782775
54MP0005387_immune_system_phenotype1.26782775
55MP0005075_abnormal_melanosome_morpholog1.26398637
56MP0008770_decreased_survivor_rate1.26387000
57MP0005310_abnormal_salivary_gland1.24272432
58MP0005623_abnormal_meninges_morphology1.20762854
59MP0000678_abnormal_parathyroid_gland1.17993699
60MP0003828_pulmonary_edema1.16729206
61MP0005666_abnormal_adipose_tissue1.16407368
62MP0005023_abnormal_wound_healing1.13145444
63MP0010234_abnormal_vibrissa_follicle1.12143492
64MP0003123_paternal_imprinting1.12063032
65MP0001727_abnormal_embryo_implantation1.11590291
66MP0004859_abnormal_synaptic_plasticity1.11318608
67MP0003111_abnormal_nucleus_morphology1.10181430
68MP0001800_abnormal_humoral_immune1.09673124
69MP0004782_abnormal_surfactant_physiolog1.09017919
70MP0003693_abnormal_embryo_hatching1.08911859
71MP0000350_abnormal_cell_proliferation1.08440894
72MP0004947_skin_inflammation1.07993315
73MP0002998_abnormal_bone_remodeling1.07428828
74MP0002970_abnormal_white_adipose1.07203426
75MP0006292_abnormal_olfactory_placode1.04165094
76MP0002396_abnormal_hematopoietic_system1.03809340
77MP0002089_abnormal_postnatal_growth/wei1.02954379
78MP0004957_abnormal_blastocyst_morpholog0.99805658
79MP0003075_altered_response_to0.99798001
80MP0004043_abnormal_pH_regulation0.99653531
81MP0002925_abnormal_cardiovascular_devel0.99560840
82MP0004197_abnormal_fetal_growth/weight/0.99265705
83MP0003283_abnormal_digestive_organ0.98656377
84MP0003448_altered_tumor_morphology0.98624630
85MP0002132_abnormal_respiratory_system0.97860733
86MP0002092_abnormal_eye_morphology0.97747297
87MP0003941_abnormal_skin_development0.97218349
88MP0003315_abnormal_perineum_morphology0.95692850
89MP0009931_abnormal_skin_appearance0.95395503
90MP0002405_respiratory_system_inflammati0.95014758
91MP0002084_abnormal_developmental_patter0.94545560
92MP0003453_abnormal_keratinocyte_physiol0.93446488
93MP0005375_adipose_tissue_phenotype0.92204816
94MP0000733_abnormal_muscle_development0.92097452
95MP0002398_abnormal_bone_marrow0.91461283
96MP0002722_abnormal_immune_system0.90120925
97MP0001216_abnormal_epidermal_layer0.90091690
98MP0000428_abnormal_craniofacial_morphol0.89402248
99MP0002060_abnormal_skin_morphology0.88583226
100MP0005000_abnormal_immune_tolerance0.88346939
101MP0000689_abnormal_spleen_morphology0.87523619
102MP0006035_abnormal_mitochondrial_morpho0.87221683
103MP0003329_amyloid_beta_deposits0.85386623
104MP0002085_abnormal_embryonic_tissue0.84946414
105MP0008004_abnormal_stomach_pH0.84639252
106MP0001835_abnormal_antigen_presentation0.84307596
107MP0001730_embryonic_growth_arrest0.80359734
108MP0001545_abnormal_hematopoietic_system0.80086208
109MP0005397_hematopoietic_system_phenotyp0.80086208
110MP0000703_abnormal_thymus_morphology0.79744577
111MP0010630_abnormal_cardiac_muscle0.79336843
112MP0009053_abnormal_anal_canal0.78950545
113MP0000377_abnormal_hair_follicle0.78320802
114MP0000858_altered_metastatic_potential0.77828829
115MP0003115_abnormal_respiratory_system0.77484643
116MP0003119_abnormal_digestive_system0.77329014
117MP0000716_abnormal_immune_system0.76522145
118MP0004272_abnormal_basement_membrane0.76396354
119MP0002452_abnormal_antigen_presenting0.76114408
120MP0002269_muscular_atrophy0.75743463
121MP0000767_abnormal_smooth_muscle0.75601359
122MP0010307_abnormal_tumor_latency0.75286135
123MP0008438_abnormal_cutaneous_collagen0.75240061
124MP0010030_abnormal_orbit_morphology0.74836166
125MP0009115_abnormal_fat_cell0.74429099
126MP0001915_intracranial_hemorrhage0.74310086
127MP0001697_abnormal_embryo_size0.74015155
128MP0002098_abnormal_vibrissa_morphology0.72855400
129MP0000490_abnormal_crypts_of0.72757794
130MP0000477_abnormal_intestine_morphology0.72712064
131MP0005025_abnormal_response_to0.72459515
132MP0004087_abnormal_muscle_fiber0.72325753
133MP0002429_abnormal_blood_cell0.72204319
134MP0004808_abnormal_hematopoietic_stem0.71498202
135MP0000313_abnormal_cell_death0.70971911
136MP0002420_abnormal_adaptive_immunity0.70951371
137MP0001819_abnormal_immune_cell0.70921934
138MP0001873_stomach_inflammation0.70890561
139MP0000759_abnormal_skeletal_muscle0.70854965
140MP0009840_abnormal_foam_cell0.70763856
141MP0002080_prenatal_lethality0.70442299
142MP0000627_abnormal_mammary_gland0.70347073
143MP0001881_abnormal_mammary_gland0.69900237
144MP0002419_abnormal_innate_immunity0.69022271
145MP0010155_abnormal_intestine_physiology0.68928783
146MP0002127_abnormal_cardiovascular_syste0.68658228
147MP0003077_abnormal_cell_cycle0.68411266
148MP0005621_abnormal_cell_physiology0.68220867
149MP0002723_abnormal_immune_serum0.66378918

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the lower motor neuron (HP:0002366)4.86135261
2Bilateral microphthalmos (HP:0007633)4.54410293
3Hypochromic microcytic anemia (HP:0004840)3.89641051
4Multiple enchondromatosis (HP:0005701)3.87640378
5Hepatoblastoma (HP:0002884)3.84532411
6Ependymoma (HP:0002888)3.38141098
7Hand muscle atrophy (HP:0009130)3.34981368
8Distal upper limb amyotrophy (HP:0007149)3.25135065
9Upper limb amyotrophy (HP:0009129)3.25135065
10Nasal polyposis (HP:0100582)3.16446893
11Rib fusion (HP:0000902)2.99146315
12Amyotrophic lateral sclerosis (HP:0007354)2.92210862
13Obstructive sleep apnea (HP:0002870)2.84426683
14Abnormality of the astrocytes (HP:0100707)2.82336070
15Astrocytoma (HP:0009592)2.82336070
16Abnormality of the nasal mucosa (HP:0000433)2.79590328
17Difficulty running (HP:0009046)2.76603972
18Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.76539320
19Thoracic kyphosis (HP:0002942)2.71396946
20Neoplasm of striated muscle (HP:0009728)2.69010722
21Abnormality of the thoracic spine (HP:0100711)2.68789637
22Achilles tendon contracture (HP:0001771)2.68019372
23Macroorchidism (HP:0000053)2.67807629
24Centrally nucleated skeletal muscle fibers (HP:0003687)2.67176495
25Neoplasm of the heart (HP:0100544)2.63394384
26Long palpebral fissure (HP:0000637)2.61849690
27Testicular atrophy (HP:0000029)2.60497368
28Generalized hypotonia (HP:0001290)2.58768797
29Broad face (HP:0000283)2.57786306
30Increased connective tissue (HP:0009025)2.56697548
31Resting tremor (HP:0002322)2.52625900
32Thin bony cortex (HP:0002753)2.50860155
33Abnormality of the Achilles tendon (HP:0005109)2.46844652
34Disproportionate tall stature (HP:0001519)2.40810664
35Ulnar bowing (HP:0003031)2.37408075
36Insomnia (HP:0100785)2.36068585
37Hypochromic anemia (HP:0001931)2.36023251
38Abnormality of the fingertips (HP:0001211)2.35514596
39Cerebral aneurysm (HP:0004944)2.34554318
40Distal lower limb amyotrophy (HP:0008944)2.34058425
41Asymmetry of the thorax (HP:0001555)2.32992078
42Renal duplication (HP:0000075)2.29901665
43Fused cervical vertebrae (HP:0002949)2.27196651
44Abnormality of the musculature of the hand (HP:0001421)2.20059063
45Dysmetric saccades (HP:0000641)2.19156032
46Deep palmar crease (HP:0006191)2.18814669
47Skin tags (HP:0010609)2.17844294
48Mitral valve prolapse (HP:0001634)2.17675447
49Rhabdomyosarcoma (HP:0002859)2.16303118
50Eczematoid dermatitis (HP:0000976)2.16087071
51Preauricular skin tag (HP:0000384)2.13027286
52Germ cell neoplasia (HP:0100728)2.12896447
53Peritonitis (HP:0002586)2.11614166
54Amblyopia (HP:0000646)2.10761495
55Pseudobulbar signs (HP:0002200)2.08793962
56Hyperparathyroidism (HP:0000843)2.08157124
57Abnormal cartilage morphology (HP:0002763)2.07490429
58Micronodular cirrhosis (HP:0001413)2.07176914
59Hyperinsulinemic hypoglycemia (HP:0000825)2.06846758
60Intestinal fistula (HP:0100819)2.06120577
61Apathy (HP:0000741)2.05396895
62Patellar dislocation (HP:0002999)2.01167999
63Colitis (HP:0002583)2.00272061
64Mildly elevated creatine phosphokinase (HP:0008180)2.00230831
65Lymphangioma (HP:0100764)1.98660574
66Abnormality of liposaccharide metabolism (HP:0010968)1.98135317
67Abnormality of glycosphingolipid metabolism (HP:0004343)1.98135317
68Abnormality of glycolipid metabolism (HP:0010969)1.98135317
69Large earlobe (HP:0009748)1.98085512
70Flat acetabular roof (HP:0003180)1.97977657
71Short humerus (HP:0005792)1.97283106
72Increased variability in muscle fiber diameter (HP:0003557)1.97227544
73Fasciculations (HP:0002380)1.97181129
74Vertebral compression fractures (HP:0002953)1.96085045
75Polygenic inheritance (HP:0010982)1.95003570
76Hyperacusis (HP:0010780)1.92658955
77Protrusio acetabuli (HP:0003179)1.92202770
78Shallow orbits (HP:0000586)1.91425291
79Premature rupture of membranes (HP:0001788)1.90925366
80Ankyloglossia (HP:0010296)1.90431939
81Abnormality of the columella (HP:0009929)1.89069644
82Hypercortisolism (HP:0001578)1.88325552
83Abnormality of the distal phalanx of the thumb (HP:0009617)1.87637075
84Diminished motivation (HP:0000745)1.87401432
85Angiofibromas (HP:0010615)1.87317422
86Adenoma sebaceum (HP:0009720)1.87317422
87Segmental peripheral demyelination/remyelination (HP:0003481)1.87080959
88Pointed chin (HP:0000307)1.87020747
89Ragged-red muscle fibers (HP:0003200)1.86663537
90Heterotopia (HP:0002282)1.85043155
91Abnormality of the salivary glands (HP:0010286)1.84850659
92Increased CSF protein (HP:0002922)1.84222044
93Horizontal nystagmus (HP:0000666)1.83790882
94Distal lower limb muscle weakness (HP:0009053)1.83574893
95Abnormality of small intestinal villus morphology (HP:0011472)1.82389291
96Villous atrophy (HP:0011473)1.82389291
97Spinal cord lesions (HP:0100561)1.82178204
98Syringomyelia (HP:0003396)1.82178204
99Annular pancreas (HP:0001734)1.81742230
100Chest pain (HP:0100749)1.81721501
101Hypopigmentation of the fundus (HP:0007894)1.80638560
102Overriding aorta (HP:0002623)1.80608520
103EMG: neuropathic changes (HP:0003445)1.80068326
104Rectal fistula (HP:0100590)1.79989902
105Rectovaginal fistula (HP:0000143)1.79989902
106Skin nodule (HP:0200036)1.79848783
107Turricephaly (HP:0000262)1.79825107
108Trismus (HP:0000211)1.79662008
109Spinal rigidity (HP:0003306)1.79576664
110Vertebral arch anomaly (HP:0008438)1.79392037
111Increased IgE level (HP:0003212)1.78080582
112Subacute progressive viral hepatitis (HP:0006572)1.77745579
113Vaginal fistula (HP:0004320)1.77333459
114Gastrointestinal inflammation (HP:0004386)1.76763193
115Aplasia/hypoplasia of the humerus (HP:0006507)1.75320505
116Elfin facies (HP:0004428)1.75089199
117Abnormality of skeletal muscle fiber size (HP:0012084)1.74917962
118Arnold-Chiari malformation (HP:0002308)1.74539034
119Genu recurvatum (HP:0002816)1.74037836
120Short 5th finger (HP:0009237)1.73639087
121Upper motor neuron abnormality (HP:0002127)1.73320423
122Tetraplegia (HP:0002445)1.71795027
123Myopathic facies (HP:0002058)1.71303665
124Slow saccadic eye movements (HP:0000514)1.71206396
125Malignant neoplasm of the central nervous system (HP:0100836)1.70525141
126Progressive muscle weakness (HP:0003323)1.70524535
127Lower limb amyotrophy (HP:0007210)1.70503956
128Cellulitis (HP:0100658)1.70348374
129Neonatal hypoglycemia (HP:0001998)1.69999512
130Aneurysm (HP:0002617)1.69465372
131Broad palm (HP:0001169)1.69425364
132Renal cell carcinoma (HP:0005584)1.69372558
133Bowel incontinence (HP:0002607)1.69324207
134Periauricular skin pits (HP:0100277)1.68658019
135Preauricular pit (HP:0004467)1.68658019
136Metaphyseal cupping (HP:0003021)1.68133494
137Spastic tetraparesis (HP:0001285)1.68048795
138Mitral regurgitation (HP:0001653)1.67967770
139Leiomyosarcoma (HP:0100243)1.67783394
140Uterine leiomyosarcoma (HP:0002891)1.67783394
141Reticulocytosis (HP:0001923)1.67525381
142Hemorrhage of the eye (HP:0011885)1.66789040
143Long eyelashes (HP:0000527)1.66324484
144Open mouth (HP:0000194)1.65881242
145Abnormality of the distal phalanges of the toes (HP:0010182)1.64291635
146Vertebral fusion (HP:0002948)1.64196610
147Radial bowing (HP:0002986)1.63476736
148Advanced eruption of teeth (HP:0006288)1.63194078
149Spinal muscular atrophy (HP:0007269)1.62714161
150Rapidly progressive (HP:0003678)1.62068028
151Neuronal loss in central nervous system (HP:0002529)1.61519659
152Cerebral inclusion bodies (HP:0100314)1.61444103
153Glioma (HP:0009733)1.61393468
154Dilatation of the ascending aorta (HP:0005111)1.60933645
155Abnormality of oral frenula (HP:0000190)1.60753725
156Fibroma (HP:0010614)1.60512471
157Precocious puberty (HP:0000826)1.60215232
158Interstitial pulmonary disease (HP:0006530)1.60147902
159Aplasia/Hypoplasia of the 5th finger (HP:0006262)1.60123355
160Septate vagina (HP:0001153)1.60038152
161Fragile skin (HP:0001030)1.59592467
162Selective tooth agenesis (HP:0001592)1.59008803
163Abnormal large intestine physiology (HP:0012700)1.58707018
164Persistence of primary teeth (HP:0006335)1.58031104
165Short nail (HP:0001799)1.57995226
166Hypercalcemia (HP:0003072)1.57861546
167Back pain (HP:0003418)1.56316581
168Multiple lipomas (HP:0001012)1.55887583
169Self-mutilation (HP:0000742)1.54896258
170Easy fatigability (HP:0003388)1.53841282
171Deviation of the thumb (HP:0009603)1.53538844
172Broad distal phalanx of finger (HP:0009836)1.52602353
173Increased cerebral lipofuscin (HP:0011813)1.51457054
174Bone pain (HP:0002653)1.51269649
175Dislocated radial head (HP:0003083)1.49327715
176Decreased motor nerve conduction velocity (HP:0003431)1.48852889
177Truncus arteriosus (HP:0001660)1.48825038
178Abnormality of macrophages (HP:0004311)1.47533552

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK126.45212212
2ERN14.45501704
3PRPF4B3.92992069
4SMG13.79878767
5GRK63.65632992
6GRK53.20784924
7TRIB33.16010196
8MAP3K102.60615865
9TYRO32.47056440
10IRAK32.08685910
11CSF1R2.05440510
12STK101.98934629
13PKN21.98339989
14MAP3K91.97678686
15NME21.95280596
16EEF2K1.84119103
17TGFBR21.78057382
18MATK1.66854666
19EPHA21.62116566
20NTRK11.48568184
21MOS1.46065018
22ALK1.44144121
23RIPK11.43878408
24TAOK21.43391813
25FGFR31.40115114
26WNK11.29315406
27TAOK11.28880484
28MAPK71.27790732
29ICK1.25844161
30BMX1.24913679
31PDGFRA1.23667719
32MARK21.23089902
33MAP4K11.22816469
34SIK21.22702031
35MAP2K31.19063997
36HIPK21.18225797
37KSR21.16147673
38MAP3K71.11781280
39GRK11.08747328
40PRKG21.08262286
41BRD41.02588714
42CSK1.00313860
43RPS6KA21.00276346
44PAK41.00051817
45CAMK40.97239397
46ADRBK20.96072311
47MTOR0.93905537
48MAP3K110.93479802
49MAP2K40.90065479
50PTK60.89684929
51PTK20.88723658
52MAP3K30.86304181
53PRKD30.86013334
54RPS6KB20.85811923
55SIK10.83713822
56LATS20.83416540
57MAP2K20.83131928
58MAP3K20.82745128
59MAP3K80.82269066
60TTK0.81572060
61PASK0.81290830
62RPS6KL10.80837495
63RPS6KC10.80837495
64ARAF0.80012821
65LRRK20.78440492
66IRAK20.76686387
67PDPK10.74635470
68RET0.73517658
69SCYL20.72551109
70BRAF0.72276687
71MAP3K140.70840132
72TTN0.70593790
73RIPK40.69260208
74PAK60.66121313
75MARK30.63858316
76JAK30.63812908
77JAK20.62674506
78PRKD20.62366221
79FGFR40.62229017
80DYRK30.59644920
81PRKCH0.59332499
82IRAK40.57563754
83MAP3K60.57102384
84RPS6KA60.55945781
85CDK70.55130149
86EPHB10.55052793
87GRK70.55007773
88HCK0.54887114
89RPS6KA10.54771124
90DAPK20.54395361
91TYK20.54156020
92JAK10.53997291
93ITK0.53536144
94DDR20.52985968
95MAPK120.52974454
96MST1R0.52722944
97SGK30.51425274
98SIK30.51287559
99PDGFRB0.50496351
100CDK40.50272474
101CHUK0.48731418
102BTK0.47823375
103TBK10.47695039
104PDK10.47242766
105MAP3K130.46987238
106ZAP700.46699295
107STK380.45748634
108LATS10.44364017
109CAMKK10.43448177
110AKT20.41417949
111NEK20.41208993
112CAMK1G0.40305472
113MAPK110.39707887
114STK30.39337430
115EGFR0.38173552
116MELK0.38065896
117IKBKB0.37983403
118STK110.37751306
119CLK10.37069756
120FGR0.35836195
121ADRBK10.35448177
122CDK90.35346266
123MAP3K10.34934920
124MAPKAPK20.32548456
125PAK20.32218191
126CHEK10.31490153
127INSR0.31027880
128DMPK0.30655830
129SYK0.30557221
130CAMK1D0.28121534
131GSK3A0.28036312
132MAPK100.27625114
133CDK60.27623913
134DYRK1B0.26870894
135NTRK30.26088222
136BLK0.25957654
137PAK30.25946393
138CDC42BPA0.24854045

Predicted pathways (KEGG)

RankGene SetZ-score
1Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.89447550
2Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.49259683
3Other glycan degradation_Homo sapiens_hsa005112.33065384
4mTOR signaling pathway_Homo sapiens_hsa041502.25903922
5Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.88371472
6Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.69838882
7Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.67577764
8B cell receptor signaling pathway_Homo sapiens_hsa046621.66551103
9Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.65032629
10VEGF signaling pathway_Homo sapiens_hsa043701.51850473
11Fructose and mannose metabolism_Homo sapiens_hsa000511.47938661
12Acute myeloid leukemia_Homo sapiens_hsa052211.47309926
13Non-small cell lung cancer_Homo sapiens_hsa052231.46431933
14Neurotrophin signaling pathway_Homo sapiens_hsa047221.43526344
15Chronic myeloid leukemia_Homo sapiens_hsa052201.41095979
16Prostate cancer_Homo sapiens_hsa052151.36943235
17Prion diseases_Homo sapiens_hsa050201.36033949
18Dorso-ventral axis formation_Homo sapiens_hsa043201.35574047
19Vitamin B6 metabolism_Homo sapiens_hsa007501.32567572
20Thyroid cancer_Homo sapiens_hsa052161.27585357
21Phospholipase D signaling pathway_Homo sapiens_hsa040721.26604627
22Glycosaminoglycan degradation_Homo sapiens_hsa005311.26428177
23Pancreatic cancer_Homo sapiens_hsa052121.26376245
24Thyroid hormone signaling pathway_Homo sapiens_hsa049191.25358000
25Central carbon metabolism in cancer_Homo sapiens_hsa052301.24521847
26Leishmaniasis_Homo sapiens_hsa051401.18863630
27Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.18128503
28Glioma_Homo sapiens_hsa052141.17572694
29Osteoclast differentiation_Homo sapiens_hsa043801.11759856
30Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.11598899
31T cell receptor signaling pathway_Homo sapiens_hsa046601.10237013
32Galactose metabolism_Homo sapiens_hsa000521.09095337
33Phosphatidylinositol signaling system_Homo sapiens_hsa040701.08385542
34Insulin resistance_Homo sapiens_hsa049311.06973640
35Adipocytokine signaling pathway_Homo sapiens_hsa049201.06946306
36Proteoglycans in cancer_Homo sapiens_hsa052051.06498121
37Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.06493465
38Regulation of actin cytoskeleton_Homo sapiens_hsa048101.05976827
39Toxoplasmosis_Homo sapiens_hsa051451.05878076
40GnRH signaling pathway_Homo sapiens_hsa049121.01494668
41Choline metabolism in cancer_Homo sapiens_hsa052311.00897541
42Prolactin signaling pathway_Homo sapiens_hsa049171.00141626
43Bladder cancer_Homo sapiens_hsa052190.99834422
44Pentose phosphate pathway_Homo sapiens_hsa000300.99247602
45Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.98383203
46Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.97401869
47AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.96958381
48Viral carcinogenesis_Homo sapiens_hsa052030.96556232
49Endometrial cancer_Homo sapiens_hsa052130.96216563
50Longevity regulating pathway - mammal_Homo sapiens_hsa042110.93402464
51Apoptosis_Homo sapiens_hsa042100.93253082
52Notch signaling pathway_Homo sapiens_hsa043300.92399604
53Inositol phosphate metabolism_Homo sapiens_hsa005620.92373890
54MicroRNAs in cancer_Homo sapiens_hsa052060.92279161
55Colorectal cancer_Homo sapiens_hsa052100.92256699
56Leukocyte transendothelial migration_Homo sapiens_hsa046700.90295271
57Rap1 signaling pathway_Homo sapiens_hsa040150.89325992
58Type II diabetes mellitus_Homo sapiens_hsa049300.89027110
59RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.87448531
60mRNA surveillance pathway_Homo sapiens_hsa030150.87219879
61Small cell lung cancer_Homo sapiens_hsa052220.86500845
62Renal cell carcinoma_Homo sapiens_hsa052110.84025775
63Long-term potentiation_Homo sapiens_hsa047200.83980247
64Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.81906808
65ErbB signaling pathway_Homo sapiens_hsa040120.80836803
66Endocytosis_Homo sapiens_hsa041440.79201180
67Measles_Homo sapiens_hsa051620.79152471
68Tuberculosis_Homo sapiens_hsa051520.78997759
69Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.78928962
70Estrogen signaling pathway_Homo sapiens_hsa049150.78442716
71AMPK signaling pathway_Homo sapiens_hsa041520.78257375
72Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.78040255
73Focal adhesion_Homo sapiens_hsa045100.77771284
74Primary immunodeficiency_Homo sapiens_hsa053400.77173077
75FoxO signaling pathway_Homo sapiens_hsa040680.74887430
76NF-kappa B signaling pathway_Homo sapiens_hsa040640.74602295
77Chemokine signaling pathway_Homo sapiens_hsa040620.74474753
78MAPK signaling pathway_Homo sapiens_hsa040100.74336536
79Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.74246698
80Antigen processing and presentation_Homo sapiens_hsa046120.73542156
81Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.72509708
82Sphingolipid signaling pathway_Homo sapiens_hsa040710.71229339
83Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.70657258
84Adherens junction_Homo sapiens_hsa045200.70275686
85Platelet activation_Homo sapiens_hsa046110.69478625
86Lysine degradation_Homo sapiens_hsa003100.68960907
87Pathways in cancer_Homo sapiens_hsa052000.68816191
88Epstein-Barr virus infection_Homo sapiens_hsa051690.68594757
89Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.67928214
90TNF signaling pathway_Homo sapiens_hsa046680.67667900
91HIF-1 signaling pathway_Homo sapiens_hsa040660.67567920
92Ribosome_Homo sapiens_hsa030100.67006295
93Influenza A_Homo sapiens_hsa051640.65708490
94Insulin signaling pathway_Homo sapiens_hsa049100.65345817
95Toll-like receptor signaling pathway_Homo sapiens_hsa046200.64557093
96Transcriptional misregulation in cancer_Homo sapiens_hsa052020.63665964
97Carbohydrate digestion and absorption_Homo sapiens_hsa049730.62931681
98Bile secretion_Homo sapiens_hsa049760.62742519
99Amoebiasis_Homo sapiens_hsa051460.62403041
100Viral myocarditis_Homo sapiens_hsa054160.60327172
101Jak-STAT signaling pathway_Homo sapiens_hsa046300.59992984
102Melanogenesis_Homo sapiens_hsa049160.59947505
103Oxytocin signaling pathway_Homo sapiens_hsa049210.58459298
104Hepatitis B_Homo sapiens_hsa051610.58097597
105Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.57345122
106Lysosome_Homo sapiens_hsa041420.56890898
107Melanoma_Homo sapiens_hsa052180.56718716
108Hepatitis C_Homo sapiens_hsa051600.55617829
109Shigellosis_Homo sapiens_hsa051310.55199849
110Malaria_Homo sapiens_hsa051440.54203748
111Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.53492396
112Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.52931836
113Biosynthesis of amino acids_Homo sapiens_hsa012300.51597939
114Herpes simplex infection_Homo sapiens_hsa051680.51319995
115Aldosterone synthesis and secretion_Homo sapiens_hsa049250.51269332
116Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.51258918
117HTLV-I infection_Homo sapiens_hsa051660.51212013
118Dilated cardiomyopathy_Homo sapiens_hsa054140.51132587
119Spliceosome_Homo sapiens_hsa030400.49994753
120Gap junction_Homo sapiens_hsa045400.49654631
121Salmonella infection_Homo sapiens_hsa051320.48324314

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