

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | nucleotide-sugar biosynthetic process (GO:0009226) | 4.60570954 |
| 2 | face development (GO:0060324) | 4.53240785 |
| 3 | regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139) | 4.35178679 |
| 4 | positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141) | 4.35178679 |
| 5 | pseudouridine synthesis (GO:0001522) | 4.35061147 |
| 6 | regulation of mitotic spindle checkpoint (GO:1903504) | 4.33910375 |
| 7 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 4.33910375 |
| 8 | mesenchymal-epithelial cell signaling (GO:0060638) | 4.18094865 |
| 9 | regulation of memory T cell differentiation (GO:0043380) | 4.14313544 |
| 10 | protein heterotetramerization (GO:0051290) | 4.09949734 |
| 11 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 4.07760825 |
| 12 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 4.07760825 |
| 13 | protein complex biogenesis (GO:0070271) | 3.97201792 |
| 14 | cytochrome complex assembly (GO:0017004) | 3.91623419 |
| 15 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.87866766 |
| 16 | termination of RNA polymerase III transcription (GO:0006386) | 3.87866766 |
| 17 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.87217165 |
| 18 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.87217165 |
| 19 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.85241008 |
| 20 | positive regulation of actin filament depolymerization (GO:0030836) | 3.81616607 |
| 21 | nucleotide transmembrane transport (GO:1901679) | 3.74895279 |
| 22 | valine metabolic process (GO:0006573) | 3.74878918 |
| 23 | chaperone-mediated protein transport (GO:0072321) | 3.74425509 |
| 24 | rRNA catabolic process (GO:0016075) | 3.67708899 |
| 25 | positive regulation of interleukin-8 secretion (GO:2000484) | 3.66850727 |
| 26 | pyrimidine-containing compound transmembrane transport (GO:0072531) | 3.61612664 |
| 27 | centriole replication (GO:0007099) | 3.61320573 |
| 28 | nucleotide-sugar metabolic process (GO:0009225) | 3.56041336 |
| 29 | histamine secretion (GO:0001821) | 3.54833027 |
| 30 | lens fiber cell differentiation (GO:0070306) | 3.52763872 |
| 31 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.51660472 |
| 32 | respiratory chain complex IV assembly (GO:0008535) | 3.38019238 |
| 33 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.35566185 |
| 34 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.35566185 |
| 35 | NADH dehydrogenase complex assembly (GO:0010257) | 3.35566185 |
| 36 | platelet dense granule organization (GO:0060155) | 3.30460452 |
| 37 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.20560151 |
| 38 | RNA phosphodiester bond hydrolysis, endonucleolytic (GO:0090502) | 3.19361996 |
| 39 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.17653867 |
| 40 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.17653867 |
| 41 | arginine catabolic process (GO:0006527) | 3.14463457 |
| 42 | inner mitochondrial membrane organization (GO:0007007) | 3.13660142 |
| 43 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.13311096 |
| 44 | negative regulation of B cell apoptotic process (GO:0002903) | 3.12187044 |
| 45 | regulation of interleukin-8 secretion (GO:2000482) | 3.09850087 |
| 46 | natural killer cell activation involved in immune response (GO:0002323) | 3.08320125 |
| 47 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.06366649 |
| 48 | regulation of helicase activity (GO:0051095) | 3.05642632 |
| 49 | rRNA methylation (GO:0031167) | 3.04557860 |
| 50 | RNA phosphodiester bond hydrolysis (GO:0090501) | 3.02675298 |
| 51 | DNA damage response, detection of DNA damage (GO:0042769) | 3.01023912 |
| 52 | rRNA modification (GO:0000154) | 3.00698826 |
| 53 | cullin deneddylation (GO:0010388) | 3.00107810 |
| 54 | regulation of odontogenesis of dentin-containing tooth (GO:0042487) | 2.98800509 |
| 55 | mitochondrial DNA replication (GO:0006264) | 2.97540091 |
| 56 | UDP-N-acetylglucosamine metabolic process (GO:0006047) | 2.95931252 |
| 57 | lactate metabolic process (GO:0006089) | 2.95918559 |
| 58 | fucose catabolic process (GO:0019317) | 2.91180919 |
| 59 | L-fucose metabolic process (GO:0042354) | 2.91180919 |
| 60 | L-fucose catabolic process (GO:0042355) | 2.91180919 |
| 61 | deoxyribonucleotide biosynthetic process (GO:0009263) | 2.84765281 |
| 62 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 2.83929529 |
| 63 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.83437069 |
| 64 | negative regulation of alpha-beta T cell differentiation (GO:0046639) | 2.83387932 |
| 65 | regulation of MHC class I biosynthetic process (GO:0045343) | 2.83039411 |
| 66 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.82264604 |
| 67 | histamine transport (GO:0051608) | 2.81924687 |
| 68 | regulation of hexokinase activity (GO:1903299) | 2.80741242 |
| 69 | regulation of glucokinase activity (GO:0033131) | 2.80741242 |
| 70 | protein deneddylation (GO:0000338) | 2.79644302 |
| 71 | regulation of mitochondrial translation (GO:0070129) | 2.78432665 |
| 72 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.76275615 |
| 73 | positive regulation of protein homodimerization activity (GO:0090073) | 2.76073350 |
| 74 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.75140689 |
| 75 | histone mRNA metabolic process (GO:0008334) | 2.74428944 |
| 76 | response to gravity (GO:0009629) | 2.74222270 |
| 77 | regulation of T-helper 1 cell differentiation (GO:0045625) | 2.73759387 |
| 78 | positive regulation of cell size (GO:0045793) | 2.73758974 |
| 79 | regulation of branching involved in salivary gland morphogenesis (GO:0060693) | 2.70959658 |
| 80 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.70571850 |
| 81 | branched-chain amino acid catabolic process (GO:0009083) | 2.68137962 |
| 82 | protein localization to cell surface (GO:0034394) | 2.58357192 |
| 83 | membrane budding (GO:0006900) | 2.57931259 |
| 84 | viral mRNA export from host cell nucleus (GO:0046784) | 2.57811539 |
| 85 | transepithelial transport (GO:0070633) | 2.57069412 |
| 86 | proteasome assembly (GO:0043248) | 2.54641685 |
| 87 | dolichol-linked oligosaccharide biosynthetic process (GO:0006488) | 2.52858381 |
| 88 | chromatin remodeling at centromere (GO:0031055) | 2.51013046 |
| 89 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.50713934 |
| 90 | ribonucleoprotein complex disassembly (GO:0032988) | 2.50501182 |
| 91 | centrosome organization (GO:0051297) | 2.49837042 |
| 92 | negative regulation of type 2 immune response (GO:0002829) | 2.49725203 |
| 93 | cellular response to exogenous dsRNA (GO:0071360) | 2.48689614 |
| 94 | Leydig cell differentiation (GO:0033327) | 2.47980715 |
| 95 | peptidyl-cysteine modification (GO:0018198) | 2.47808389 |
| 96 | telomere maintenance via recombination (GO:0000722) | 2.47697940 |
| 97 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.47538656 |
| 98 | intestinal epithelial cell development (GO:0060576) | 2.47328985 |
| 99 | ncRNA catabolic process (GO:0034661) | 2.47120910 |
| 100 | CENP-A containing nucleosome assembly (GO:0034080) | 2.46893693 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.26023621 |
| 2 | ELK1_19687146_ChIP-ChIP_HELA_Human | 3.02679458 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.97873783 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.95691068 |
| 5 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.76646239 |
| 6 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.68712358 |
| 7 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.63340767 |
| 8 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.45160501 |
| 9 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 2.44971291 |
| 10 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.40083652 |
| 11 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.28986729 |
| 12 | GATA1_22025678_ChIP-Seq_K562_Human | 2.14841947 |
| 13 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.13436519 |
| 14 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.04127116 |
| 15 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.98241840 |
| 16 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.97870561 |
| 17 | EWS_26573619_Chip-Seq_HEK293_Human | 1.96656405 |
| 18 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.94688647 |
| 19 | P300_19829295_ChIP-Seq_ESCs_Human | 1.92551052 |
| 20 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.90493295 |
| 21 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.85173654 |
| 22 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.81840036 |
| 23 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.79501898 |
| 24 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.77030480 |
| 25 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.76304700 |
| 26 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.75938904 |
| 27 | FUS_26573619_Chip-Seq_HEK293_Human | 1.72315828 |
| 28 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.66732129 |
| 29 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.64739862 |
| 30 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.63414066 |
| 31 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.61440820 |
| 32 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.61051777 |
| 33 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.60279688 |
| 34 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.60178828 |
| 35 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.57607929 |
| 36 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.49678955 |
| 37 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.48245055 |
| 38 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.47076943 |
| 39 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.44353135 |
| 40 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.42552259 |
| 41 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.37208294 |
| 42 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.37206138 |
| 43 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.32314903 |
| 44 | BRD4_25478319_ChIP-Seq_HGPS_Human | 1.31045321 |
| 45 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.28858825 |
| 46 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.28583891 |
| 47 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.27354695 |
| 48 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.26517380 |
| 49 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.24203141 |
| 50 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.23342149 |
| 51 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.23185064 |
| 52 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.23040847 |
| 53 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.23040847 |
| 54 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.22641659 |
| 55 | CJUN_26792858_Chip-Seq_BT549_Human | 1.22576397 |
| 56 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.21334805 |
| 57 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.20454705 |
| 58 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.18269248 |
| 59 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.18118670 |
| 60 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.17007227 |
| 61 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.16625185 |
| 62 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.16364688 |
| 63 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.15047645 |
| 64 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.14928362 |
| 65 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.14559352 |
| 66 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.14559352 |
| 67 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.14474498 |
| 68 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.13640049 |
| 69 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.13640049 |
| 70 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.13303608 |
| 71 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.10996888 |
| 72 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.10334792 |
| 73 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.09845019 |
| 74 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.09597174 |
| 75 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.09490970 |
| 76 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.09337409 |
| 77 | ELF5_23300383_ChIP-Seq_T47D_Human | 1.07810824 |
| 78 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.07153115 |
| 79 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.05062134 |
| 80 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.04939337 |
| 81 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.04750216 |
| 82 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.04735146 |
| 83 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.04712562 |
| 84 | VDR_22108803_ChIP-Seq_LS180_Human | 1.03923448 |
| 85 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.03118194 |
| 86 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.02408855 |
| 87 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.02171090 |
| 88 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.01814598 |
| 89 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.01662183 |
| 90 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.01163496 |
| 91 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.00381615 |
| 92 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.00215652 |
| 93 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.98990183 |
| 94 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.98292426 |
| 95 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.97685551 |
| 96 | ETV1_20927104_ChIP-Seq_GIST48_Human | 0.97068648 |
| 97 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 0.96770558 |
| 98 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.96534263 |
| 99 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.96277072 |
| 100 | GATA4_25053715_ChIP-Seq_YYC3_Human | 0.96110795 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003950_abnormal_plasma_membrane | 5.60678656 |
| 2 | MP0003806_abnormal_nucleotide_metabolis | 4.19279325 |
| 3 | MP0003300_gastrointestinal_ulcer | 3.71072048 |
| 4 | MP0008057_abnormal_DNA_replication | 2.98710609 |
| 5 | MP0006054_spinal_hemorrhage | 2.82425947 |
| 6 | MP0010386_abnormal_urinary_bladder | 2.72488934 |
| 7 | MP0005084_abnormal_gallbladder_morpholo | 2.68244711 |
| 8 | MP0002876_abnormal_thyroid_physiology | 2.63995072 |
| 9 | MP0009780_abnormal_chondrocyte_physiolo | 2.61559727 |
| 10 | MP0003693_abnormal_embryo_hatching | 2.51352589 |
| 11 | MP0000569_abnormal_digit_pigmentation | 2.38896976 |
| 12 | MP0000538_abnormal_urinary_bladder | 2.31718112 |
| 13 | MP0008058_abnormal_DNA_repair | 2.08273330 |
| 14 | MP0002132_abnormal_respiratory_system | 2.07539954 |
| 15 | MP0003186_abnormal_redox_activity | 1.99798026 |
| 16 | MP0004134_abnormal_chest_morphology | 1.96449642 |
| 17 | MP0003252_abnormal_bile_duct | 1.95381010 |
| 18 | MP0003718_maternal_effect | 1.93273571 |
| 19 | MP0002127_abnormal_cardiovascular_syste | 1.90674260 |
| 20 | MP0002163_abnormal_gland_morphology | 1.84288280 |
| 21 | MP0005220_abnormal_exocrine_pancreas | 1.81215255 |
| 22 | MP0003011_delayed_dark_adaptation | 1.81172680 |
| 23 | MP0008007_abnormal_cellular_replicative | 1.77953809 |
| 24 | MP0005395_other_phenotype | 1.67927280 |
| 25 | MP0002938_white_spotting | 1.63743667 |
| 26 | MP0002160_abnormal_reproductive_system | 1.55949255 |
| 27 | MP0005023_abnormal_wound_healing | 1.54529199 |
| 28 | MP0002138_abnormal_hepatobiliary_system | 1.53368852 |
| 29 | MP0002396_abnormal_hematopoietic_system | 1.49630633 |
| 30 | MP0003195_calcinosis | 1.49455005 |
| 31 | MP0010094_abnormal_chromosome_stability | 1.47972520 |
| 32 | MP0002282_abnormal_trachea_morphology | 1.47104688 |
| 33 | MP0002837_dystrophic_cardiac_calcinosis | 1.44494815 |
| 34 | MP0004084_abnormal_cardiac_muscle | 1.40899950 |
| 35 | MP0002928_abnormal_bile_duct | 1.34608225 |
| 36 | MP0004019_abnormal_vitamin_homeostasis | 1.34073756 |
| 37 | MP0002168_other_aberrant_phenotype | 1.33308207 |
| 38 | MP0000343_altered_response_to | 1.32285999 |
| 39 | MP0008872_abnormal_physiological_respon | 1.28149800 |
| 40 | MP0002277_abnormal_respiratory_mucosa | 1.28144801 |
| 41 | MP0001756_abnormal_urination | 1.25991229 |
| 42 | MP0003279_aneurysm | 1.22566814 |
| 43 | MP0004133_heterotaxia | 1.20557482 |
| 44 | MP0009697_abnormal_copulation | 1.19207522 |
| 45 | MP0000613_abnormal_salivary_gland | 1.16205894 |
| 46 | MP0001542_abnormal_bone_strength | 1.15681921 |
| 47 | MP0001529_abnormal_vocalization | 1.14730326 |
| 48 | MP0002295_abnormal_pulmonary_circulatio | 1.14431006 |
| 49 | MP0009250_abnormal_appendicular_skeleto | 1.10917003 |
| 50 | MP0001485_abnormal_pinna_reflex | 1.09701557 |
| 51 | MP0003943_abnormal_hepatobiliary_system | 1.09317246 |
| 52 | MP0004957_abnormal_blastocyst_morpholog | 1.09256945 |
| 53 | MP0001243_abnormal_dermal_layer | 1.06854625 |
| 54 | MP0005174_abnormal_tail_pigmentation | 1.02407036 |
| 55 | MP0004215_abnormal_myocardial_fiber | 1.00644672 |
| 56 | MP0005389_reproductive_system_phenotype | 0.99738022 |
| 57 | MP0005379_endocrine/exocrine_gland_phen | 0.99390220 |
| 58 | MP0005166_decreased_susceptibility_to | 0.96151667 |
| 59 | MP0002254_reproductive_system_inflammat | 0.94893112 |
| 60 | MP0003137_abnormal_impulse_conducting | 0.94809237 |
| 61 | MP0000013_abnormal_adipose_tissue | 0.94495867 |
| 62 | MP0006036_abnormal_mitochondrial_physio | 0.94264540 |
| 63 | MP0002405_respiratory_system_inflammati | 0.90838357 |
| 64 | MP0009764_decreased_sensitivity_to | 0.89770469 |
| 65 | MP0001879_abnormal_lymphatic_vessel | 0.89689054 |
| 66 | MP0002735_abnormal_chemical_nociception | 0.87756132 |
| 67 | MP0000762_abnormal_tongue_morphology | 0.87232980 |
| 68 | MP0004272_abnormal_basement_membrane | 0.86790393 |
| 69 | MP0002148_abnormal_hypersensitivity_rea | 0.86319967 |
| 70 | MP0003786_premature_aging | 0.85086092 |
| 71 | MP0002060_abnormal_skin_morphology | 0.81724367 |
| 72 | MP0000516_abnormal_urinary_system | 0.79724533 |
| 73 | MP0005367_renal/urinary_system_phenotyp | 0.79724533 |
| 74 | MP0002233_abnormal_nose_morphology | 0.77867592 |
| 75 | MP0010368_abnormal_lymphatic_system | 0.77676236 |
| 76 | MP0003448_altered_tumor_morphology | 0.77428399 |
| 77 | MP0003937_abnormal_limbs/digits/tail_de | 0.77171767 |
| 78 | MP0002736_abnormal_nociception_after | 0.76401405 |
| 79 | MP0009053_abnormal_anal_canal | 0.75324945 |
| 80 | MP0003866_abnormal_defecation | 0.75107462 |
| 81 | MP0005332_abnormal_amino_acid | 0.74129680 |
| 82 | MP0001984_abnormal_olfaction | 0.73478098 |
| 83 | MP0000427_abnormal_hair_cycle | 0.72644132 |
| 84 | MP0003077_abnormal_cell_cycle | 0.70898511 |
| 85 | MP0006082_CNS_inflammation | 0.70248475 |
| 86 | MP0005266_abnormal_metabolism | 0.69605681 |
| 87 | MP0008789_abnormal_olfactory_epithelium | 0.68837473 |
| 88 | MP0008877_abnormal_DNA_methylation | 0.68720922 |
| 89 | MP0001666_abnormal_nutrient_absorption | 0.65254710 |
| 90 | MP0001764_abnormal_homeostasis | 0.65208396 |
| 91 | MP0002109_abnormal_limb_morphology | 0.65048054 |
| 92 | MP0010030_abnormal_orbit_morphology | 0.64293745 |
| 93 | MP0003936_abnormal_reproductive_system | 0.63936482 |
| 94 | MP0001270_distended_abdomen | 0.63646901 |
| 95 | MP0010678_abnormal_skin_adnexa | 0.63608184 |
| 96 | MP0000383_abnormal_hair_follicle | 0.63607977 |
| 97 | MP0006035_abnormal_mitochondrial_morpho | 0.63074551 |
| 98 | MP0001177_atelectasis | 0.62082029 |
| 99 | MP0004142_abnormal_muscle_tone | 0.61948917 |
| 100 | MP0000653_abnormal_sex_gland | 0.61398451 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Short middle phalanx of the 5th finger (HP:0004220) | 5.12618807 |
| 2 | Sensory axonal neuropathy (HP:0003390) | 4.29489837 |
| 3 | Aplastic anemia (HP:0001915) | 4.07344753 |
| 4 | Spastic paraparesis (HP:0002313) | 3.63861967 |
| 5 | Spondylolisthesis (HP:0003302) | 3.49074999 |
| 6 | Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161) | 3.48569707 |
| 7 | Stillbirth (HP:0003826) | 3.44326655 |
| 8 | Abnormal tarsal ossification (HP:0008369) | 3.30343046 |
| 9 | Abnormal foot bone ossification (HP:0010675) | 3.17475972 |
| 10 | Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376) | 3.14721750 |
| 11 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 3.09710746 |
| 12 | Depressed nasal tip (HP:0000437) | 3.06084875 |
| 13 | Aplasia/Hypoplasia of the scapulae (HP:0006713) | 2.99311684 |
| 14 | Hypoplastic scapulae (HP:0000882) | 2.99311684 |
| 15 | Bifid tongue (HP:0010297) | 2.98387916 |
| 16 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.93837536 |
| 17 | Abnormality of placental membranes (HP:0011409) | 2.88420408 |
| 18 | Amniotic constriction ring (HP:0009775) | 2.88420408 |
| 19 | Popliteal pterygium (HP:0009756) | 2.86756494 |
| 20 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 2.83473851 |
| 21 | Increased number of teeth (HP:0011069) | 2.83317253 |
| 22 | Severe visual impairment (HP:0001141) | 2.69637260 |
| 23 | Chromsome breakage (HP:0040012) | 2.68986921 |
| 24 | Increased hepatocellular lipid droplets (HP:0006565) | 2.65281539 |
| 25 | Methylmalonic acidemia (HP:0002912) | 2.63747712 |
| 26 | Aplasia/Hypoplasia of the frontal sinuses (HP:0009119) | 2.63364632 |
| 27 | Short 5th finger (HP:0009237) | 2.61587257 |
| 28 | Lipid accumulation in hepatocytes (HP:0006561) | 2.57557522 |
| 29 | Hepatocellular necrosis (HP:0001404) | 2.57536304 |
| 30 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.49266002 |
| 31 | Mitochondrial inheritance (HP:0001427) | 2.42296499 |
| 32 | Type II lissencephaly (HP:0007260) | 2.41025113 |
| 33 | Congenital, generalized hypertrichosis (HP:0004540) | 2.40415460 |
| 34 | Microvesicular hepatic steatosis (HP:0001414) | 2.40045039 |
| 35 | Colon cancer (HP:0003003) | 2.39761680 |
| 36 | Aplasia/Hypoplasia of the 5th finger (HP:0006262) | 2.39664111 |
| 37 | Neonatal respiratory distress (HP:0002643) | 2.38798043 |
| 38 | Increased CSF lactate (HP:0002490) | 2.35889612 |
| 39 | Tubulointerstitial nephritis (HP:0001970) | 2.33785157 |
| 40 | Type 2 muscle fiber atrophy (HP:0003554) | 2.29566111 |
| 41 | Cerebral hypomyelination (HP:0006808) | 2.27861108 |
| 42 | Abnormality of the pons (HP:0007361) | 2.26331073 |
| 43 | Microretrognathia (HP:0000308) | 2.24214747 |
| 44 | Type I transferrin isoform profile (HP:0003642) | 2.23033373 |
| 45 | Stenosis of the external auditory canal (HP:0000402) | 2.22624811 |
| 46 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.20130000 |
| 47 | Medulloblastoma (HP:0002885) | 2.18881184 |
| 48 | Acute necrotizing encephalopathy (HP:0006965) | 2.18663856 |
| 49 | Metaphyseal dysplasia (HP:0100255) | 2.17548015 |
| 50 | Renal Fanconi syndrome (HP:0001994) | 2.05691654 |
| 51 | Progressive macrocephaly (HP:0004481) | 2.05177061 |
| 52 | Hypoplasia of the pons (HP:0012110) | 2.04802246 |
| 53 | Methylmalonic aciduria (HP:0012120) | 2.03655077 |
| 54 | Syringomyelia (HP:0003396) | 2.03293236 |
| 55 | Spinal cord lesions (HP:0100561) | 2.03293236 |
| 56 | Abnormality of the frontal sinuses (HP:0002687) | 2.01548676 |
| 57 | Cupped ribs (HP:0000887) | 2.01496694 |
| 58 | Hypoplastic iliac wings (HP:0002866) | 2.00289837 |
| 59 | Abnormality of the ileum (HP:0001549) | 2.00000882 |
| 60 | Meckel diverticulum (HP:0002245) | 1.97471694 |
| 61 | Abnormal protein glycosylation (HP:0012346) | 1.97007355 |
| 62 | Abnormal glycosylation (HP:0012345) | 1.97007355 |
| 63 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.97007355 |
| 64 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.97007355 |
| 65 | Hepatic necrosis (HP:0002605) | 1.94849269 |
| 66 | Aplasia/Hypoplasia involving the sinuses (HP:0009120) | 1.91072630 |
| 67 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.91007054 |
| 68 | Respiratory difficulties (HP:0002880) | 1.90706948 |
| 69 | Molar tooth sign on MRI (HP:0002419) | 1.90520805 |
| 70 | Abnormality of midbrain morphology (HP:0002418) | 1.90520805 |
| 71 | Sloping forehead (HP:0000340) | 1.89800681 |
| 72 | Birth length less than 3rd percentile (HP:0003561) | 1.89240566 |
| 73 | Acute myeloid leukemia (HP:0004808) | 1.88664084 |
| 74 | Cerebral edema (HP:0002181) | 1.88566541 |
| 75 | Ependymoma (HP:0002888) | 1.88378771 |
| 76 | Median cleft lip (HP:0000161) | 1.86394565 |
| 77 | Abnormality of the preputium (HP:0100587) | 1.85844060 |
| 78 | Sparse eyelashes (HP:0000653) | 1.85267782 |
| 79 | Cerebellar dysplasia (HP:0007033) | 1.84965991 |
| 80 | Duplicated collecting system (HP:0000081) | 1.84600685 |
| 81 | Absent frontal sinuses (HP:0002688) | 1.84214981 |
| 82 | Muscle fiber atrophy (HP:0100295) | 1.84070803 |
| 83 | Short middle phalanx of finger (HP:0005819) | 1.82527824 |
| 84 | Small intestinal stenosis (HP:0012848) | 1.81350750 |
| 85 | Duodenal stenosis (HP:0100867) | 1.81350750 |
| 86 | Poor head control (HP:0002421) | 1.80380345 |
| 87 | Supernumerary spleens (HP:0009799) | 1.79931391 |
| 88 | Clubbing of toes (HP:0100760) | 1.79592381 |
| 89 | Barrel-shaped chest (HP:0001552) | 1.79409227 |
| 90 | Volvulus (HP:0002580) | 1.78645376 |
| 91 | Abnormality of pyrimidine metabolism (HP:0004353) | 1.78188380 |
| 92 | Abnormal lung lobation (HP:0002101) | 1.77061681 |
| 93 | Medial flaring of the eyebrow (HP:0010747) | 1.76899470 |
| 94 | Abnormality of the renal collecting system (HP:0004742) | 1.76892477 |
| 95 | Hypochromic microcytic anemia (HP:0004840) | 1.74874424 |
| 96 | Abnormality of the duodenum (HP:0002246) | 1.73944253 |
| 97 | Abnormality of DNA repair (HP:0003254) | 1.73520977 |
| 98 | Hypoproteinemia (HP:0003075) | 1.73385193 |
| 99 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.73184401 |
| 100 | Irregular vertebral endplates (HP:0003301) | 1.73108998 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TRIM28 | 4.44295632 |
| 2 | MAP4K2 | 3.35650310 |
| 3 | FRK | 3.31946914 |
| 4 | STK39 | 2.98718736 |
| 5 | SIK3 | 2.95169196 |
| 6 | TAF1 | 2.89111476 |
| 7 | MAP3K12 | 2.83624045 |
| 8 | LMTK2 | 2.82250824 |
| 9 | MST4 | 2.80044085 |
| 10 | EIF2AK3 | 2.59826016 |
| 11 | VRK2 | 2.55102462 |
| 12 | BCR | 2.36318542 |
| 13 | STK16 | 2.33197864 |
| 14 | PIK3CA | 2.22300754 |
| 15 | SRPK1 | 2.17041099 |
| 16 | FLT3 | 1.87588772 |
| 17 | OXSR1 | 1.83861442 |
| 18 | GRK1 | 1.81540447 |
| 19 | PBK | 1.66045805 |
| 20 | MYLK | 1.64306780 |
| 21 | MKNK1 | 1.59571354 |
| 22 | ZAK | 1.57830421 |
| 23 | MAP3K3 | 1.56816106 |
| 24 | TNIK | 1.56205224 |
| 25 | TAOK3 | 1.55651568 |
| 26 | NUAK1 | 1.53397628 |
| 27 | BRSK2 | 1.50350518 |
| 28 | NME1 | 1.49782295 |
| 29 | MKNK2 | 1.45296894 |
| 30 | PLK3 | 1.36776632 |
| 31 | PIM2 | 1.17591728 |
| 32 | STK38 | 1.15347394 |
| 33 | STK38L | 1.12435269 |
| 34 | TEC | 1.11380571 |
| 35 | DAPK1 | 1.07931477 |
| 36 | CDK19 | 1.07656512 |
| 37 | LIMK1 | 1.01265037 |
| 38 | STK3 | 1.01236427 |
| 39 | PAK3 | 0.99015675 |
| 40 | KIT | 0.94928540 |
| 41 | EIF2AK1 | 0.86108219 |
| 42 | STK4 | 0.84764358 |
| 43 | PIK3CG | 0.83513884 |
| 44 | WNK4 | 0.83023212 |
| 45 | EPHA2 | 0.82005773 |
| 46 | FER | 0.81917576 |
| 47 | BMPR1B | 0.72932276 |
| 48 | BRD4 | 0.71557651 |
| 49 | NLK | 0.71283381 |
| 50 | PRKCE | 0.70436595 |
| 51 | DAPK2 | 0.68645560 |
| 52 | STK10 | 0.68566313 |
| 53 | BCKDK | 0.68431926 |
| 54 | AKT3 | 0.68023678 |
| 55 | PLK1 | 0.67961808 |
| 56 | RPS6KA4 | 0.66561665 |
| 57 | NEK1 | 0.65046407 |
| 58 | CSNK1G1 | 0.63305155 |
| 59 | VRK1 | 0.62517244 |
| 60 | PRKD3 | 0.60897389 |
| 61 | PRKD2 | 0.56871937 |
| 62 | PDK2 | 0.56636300 |
| 63 | BUB1 | 0.55049136 |
| 64 | CSNK2A2 | 0.52759290 |
| 65 | PRKCI | 0.50871777 |
| 66 | CSNK1G2 | 0.50568047 |
| 67 | CSNK1G3 | 0.49699497 |
| 68 | WNK3 | 0.49384103 |
| 69 | RAF1 | 0.49337422 |
| 70 | PLK2 | 0.47214798 |
| 71 | MUSK | 0.45211900 |
| 72 | GRK7 | 0.45104863 |
| 73 | PRKD1 | 0.45006211 |
| 74 | MINK1 | 0.44190086 |
| 75 | CSNK1A1L | 0.44112899 |
| 76 | TSSK6 | 0.43965683 |
| 77 | CSNK2A1 | 0.41946689 |
| 78 | PNCK | 0.40840964 |
| 79 | GSK3A | 0.40334664 |
| 80 | PAK2 | 0.40227198 |
| 81 | ABL1 | 0.37553634 |
| 82 | DAPK3 | 0.36409236 |
| 83 | DYRK2 | 0.35685855 |
| 84 | ILK | 0.33512933 |
| 85 | KSR1 | 0.33064531 |
| 86 | DYRK3 | 0.33004285 |
| 87 | MAPKAPK5 | 0.32852975 |
| 88 | CSNK1A1 | 0.32306967 |
| 89 | ERBB3 | 0.32169251 |
| 90 | DYRK1A | 0.31547847 |
| 91 | PAK4 | 0.30583903 |
| 92 | PRKCQ | 0.30563014 |
| 93 | PRKG2 | 0.29584324 |
| 94 | CAMK1 | 0.29308409 |
| 95 | CSNK1E | 0.28487343 |
| 96 | DDR2 | 0.28081507 |
| 97 | NEK6 | 0.27769031 |
| 98 | CASK | 0.27718430 |
| 99 | ADRBK1 | 0.27547554 |
| 100 | BRSK1 | 0.27194970 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 3.58411900 |
| 2 | RNA polymerase_Homo sapiens_hsa03020 | 3.52502100 |
| 3 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.41455813 |
| 4 | Protein export_Homo sapiens_hsa03060 | 3.38699235 |
| 5 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 3.35830163 |
| 6 | Mismatch repair_Homo sapiens_hsa03430 | 3.09790501 |
| 7 | DNA replication_Homo sapiens_hsa03030 | 2.48860106 |
| 8 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.30580426 |
| 9 | Homologous recombination_Homo sapiens_hsa03440 | 2.10173086 |
| 10 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.06337619 |
| 11 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 2.02878010 |
| 12 | Steroid biosynthesis_Homo sapiens_hsa00100 | 2.01638179 |
| 13 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.95336562 |
| 14 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.94513165 |
| 15 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.85895434 |
| 16 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.84586922 |
| 17 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.83779446 |
| 18 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.83770199 |
| 19 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.77151018 |
| 20 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.73679797 |
| 21 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.71565798 |
| 22 | RNA degradation_Homo sapiens_hsa03018 | 1.69203595 |
| 23 | Basal transcription factors_Homo sapiens_hsa03022 | 1.68524469 |
| 24 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.65630619 |
| 25 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.56363197 |
| 26 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.56145266 |
| 27 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.54057828 |
| 28 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.51014871 |
| 29 | Parkinsons disease_Homo sapiens_hsa05012 | 1.50375593 |
| 30 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.46501604 |
| 31 | Ribosome_Homo sapiens_hsa03010 | 1.44655412 |
| 32 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.43580928 |
| 33 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.42170266 |
| 34 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.41342246 |
| 35 | RNA transport_Homo sapiens_hsa03013 | 1.36808966 |
| 36 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.30166740 |
| 37 | Purine metabolism_Homo sapiens_hsa00230 | 1.27914998 |
| 38 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.25237212 |
| 39 | Base excision repair_Homo sapiens_hsa03410 | 1.23364015 |
| 40 | Huntingtons disease_Homo sapiens_hsa05016 | 1.17220253 |
| 41 | Sulfur relay system_Homo sapiens_hsa04122 | 1.09710822 |
| 42 | Peroxisome_Homo sapiens_hsa04146 | 1.08324297 |
| 43 | Phototransduction_Homo sapiens_hsa04744 | 0.97345358 |
| 44 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.94713421 |
| 45 | Alzheimers disease_Homo sapiens_hsa05010 | 0.89485566 |
| 46 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.88938215 |
| 47 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.83906753 |
| 48 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.80087865 |
| 49 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.79131331 |
| 50 | Melanoma_Homo sapiens_hsa05218 | 0.78703092 |
| 51 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.70966999 |
| 52 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.70845917 |
| 53 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.69752767 |
| 54 | Olfactory transduction_Homo sapiens_hsa04740 | 0.69084821 |
| 55 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.68927395 |
| 56 | Metabolic pathways_Homo sapiens_hsa01100 | 0.67158174 |
| 57 | Cell cycle_Homo sapiens_hsa04110 | 0.64854231 |
| 58 | Tight junction_Homo sapiens_hsa04530 | 0.64470976 |
| 59 | Spliceosome_Homo sapiens_hsa03040 | 0.62746740 |
| 60 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.61853600 |
| 61 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.61720167 |
| 62 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.61120143 |
| 63 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.60475733 |
| 64 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.58120525 |
| 65 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.57963801 |
| 66 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.57244664 |
| 67 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.56943339 |
| 68 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.54729276 |
| 69 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.53855420 |
| 70 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.53679796 |
| 71 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.53109164 |
| 72 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.51014821 |
| 73 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.44884262 |
| 74 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.43208616 |
| 75 | Retinol metabolism_Homo sapiens_hsa00830 | 0.42590161 |
| 76 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.42207569 |
| 77 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.40603289 |
| 78 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.40590802 |
| 79 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.39933364 |
| 80 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.38057038 |
| 81 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.35010191 |
| 82 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.34456088 |
| 83 | Mineral absorption_Homo sapiens_hsa04978 | 0.32194209 |
| 84 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.31282703 |
| 85 | Other glycan degradation_Homo sapiens_hsa00511 | 0.31139197 |
| 86 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.30628629 |
| 87 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.29222734 |
| 88 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.27702957 |
| 89 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.27626093 |
| 90 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.25414242 |
| 91 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.24402525 |
| 92 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.24213927 |
| 93 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.24076092 |
| 94 | Taste transduction_Homo sapiens_hsa04742 | 0.23762949 |
| 95 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.23343723 |
| 96 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.22111102 |
| 97 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.22047945 |
| 98 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.21565958 |
| 99 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.21513288 |
| 100 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.20141394 |

