BANF2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1spermatid development (GO:0007286)9.86967939
2plasma membrane fusion (GO:0045026)9.83133557
3epithelial cilium movement (GO:0003351)9.55727334
4axonemal dynein complex assembly (GO:0070286)9.30295403
5motile cilium assembly (GO:0044458)9.17454366
6reproduction (GO:0000003)9.01819861
7regulation of cilium movement (GO:0003352)8.34598715
8response to pheromone (GO:0019236)8.08106353
9cilium or flagellum-dependent cell motility (GO:0001539)7.74355775
10cilium movement (GO:0003341)7.63192154
11negative regulation of inclusion body assembly (GO:0090084)7.27451512
12sperm capacitation (GO:0048240)7.17637634
13organic cation transport (GO:0015695)7.16103482
14single fertilization (GO:0007338)7.13610428
15spermatogenesis (GO:0007283)7.05275270
16male gamete generation (GO:0048232)7.02566258
17epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)6.96106076
18synaptonemal complex organization (GO:0070193)6.91445135
19synaptonemal complex assembly (GO:0007130)6.84813772
20male meiosis (GO:0007140)6.58798411
21piRNA metabolic process (GO:0034587)6.46363857
22gamete generation (GO:0007276)6.44891835
23microtubule depolymerization (GO:0007019)6.36292031
24fertilization (GO:0009566)6.13913796
25cartilage development involved in endochondral bone morphogenesis (GO:0060351)6.10735197
26regulation of inclusion body assembly (GO:0090083)6.10714892
27phosphatidylethanolamine biosynthetic process (GO:0006646)5.95218574
28chromosome condensation (GO:0030261)5.94708945
29calcium ion-dependent exocytosis (GO:0017156)5.73952106
30DNA packaging (GO:0006323)5.68156276
31germ cell development (GO:0007281)5.56165432
32phosphatidylethanolamine metabolic process (GO:0046337)5.55075539
33cellular process involved in reproduction in multicellular organism (GO:0022412)5.51892021
34rRNA methylation (GO:0031167)5.27926479
35cellular ketone body metabolic process (GO:0046950)5.14238416
36glycerol ether metabolic process (GO:0006662)5.08345303
37seminiferous tubule development (GO:0072520)5.07485007
38multicellular organismal reproductive process (GO:0048609)5.07437703
39cell recognition (GO:0008037)5.03686744
40multicellular organismal movement (GO:0050879)5.03269616
41musculoskeletal movement (GO:0050881)5.03269616
42protein targeting to Golgi (GO:0000042)4.98604586
43ventricular system development (GO:0021591)4.95032265
44establishment of protein localization to Golgi (GO:0072600)4.90394766
45regulation of microtubule-based movement (GO:0060632)4.89716733
46microtubule severing (GO:0051013)4.89203825
47spermatid nucleus differentiation (GO:0007289)4.89175959
48centriole replication (GO:0007099)4.76647172
49ether metabolic process (GO:0018904)4.69521485
50rRNA modification (GO:0000154)4.63798334
51male meiosis I (GO:0007141)4.62468637
52retrograde transport, vesicle recycling within Golgi (GO:0000301)4.58183834
53sequestering of actin monomers (GO:0042989)4.57020605
54chromosome organization involved in meiosis (GO:0070192)4.56160022
55ketone body metabolic process (GO:1902224)4.56071305
56positive regulation of Rab GTPase activity (GO:0032851)4.52449018
57regulation of Rab GTPase activity (GO:0032313)4.52449018
58sexual reproduction (GO:0019953)4.39783006
59outflow tract septum morphogenesis (GO:0003148)4.31639654
60regulation of transcription involved in cell fate commitment (GO:0060850)4.30442908
61left/right pattern formation (GO:0060972)4.27760481
62DNA methylation involved in gamete generation (GO:0043046)4.26238273
63single strand break repair (GO:0000012)4.20515291
64regulation of centriole replication (GO:0046599)4.19568016
65chaperone-mediated protein complex assembly (GO:0051131)4.10915225
66centriole assembly (GO:0098534)4.10268617
67multicellular organismal development (GO:0007275)4.09948236
68protein localization to Golgi apparatus (GO:0034067)3.98826906
69meiotic nuclear division (GO:0007126)3.98775697
70cerebral cortex neuron differentiation (GO:0021895)3.93705394
71positive regulation of action potential (GO:0045760)3.88982771
72regulation of female gonad development (GO:2000194)3.81445963
73regulation of spindle checkpoint (GO:0090231)3.70414735
74meiosis I (GO:0007127)3.69050635
75interferon-gamma secretion (GO:0072643)3.68637811
76protein K11-linked deubiquitination (GO:0035871)3.67296089
77nucleoside transmembrane transport (GO:1901642)3.64668815
78protein polyglutamylation (GO:0018095)3.51495197
79genitalia morphogenesis (GO:0035112)3.49614724
80negative regulation of Rho protein signal transduction (GO:0035024)3.48590356
81coenzyme catabolic process (GO:0009109)3.40679241
82RNA destabilization (GO:0050779)3.37561078
83positive regulation of macrophage activation (GO:0043032)3.34165451
84polyamine biosynthetic process (GO:0006596)3.24563307
85protein refolding (GO:0042026)3.23504702
86microtubule polymerization or depolymerization (GO:0031109)3.19495347
87neurofilament cytoskeleton organization (GO:0060052)3.18924893
88RNA localization (GO:0006403)3.18614801
89primary amino compound metabolic process (GO:1901160)3.18210576
90carnitine transport (GO:0015879)3.15092741
91amino-acid betaine transport (GO:0015838)3.15092741
92meiotic cell cycle (GO:0051321)3.13391862
93retinoic acid receptor signaling pathway (GO:0048384)3.11585069
94protein localization to cilium (GO:0061512)3.11293639
95aggressive behavior (GO:0002118)3.10464965
96behavioral response to nicotine (GO:0035095)3.09538672
97nucleus organization (GO:0006997)3.06920327
98metanephric tubule development (GO:0072170)3.06716608
99metanephric nephron tubule development (GO:0072234)3.06716608
100response to acidic pH (GO:0010447)3.02680542
101nucleoside diphosphate phosphorylation (GO:0006165)2.98131421
102carnitine transmembrane transport (GO:1902603)2.97275498
103glycolytic process (GO:0006096)2.96690704
104monoubiquitinated protein deubiquitination (GO:0035520)2.96353862
105striatum development (GO:0021756)2.92989175
106cellular response to pH (GO:0071467)2.92519751
107neuronal action potential (GO:0019228)2.88982437
108alditol metabolic process (GO:0019400)2.88650011
109C4-dicarboxylate transport (GO:0015740)2.86263243
110chemosensory behavior (GO:0007635)2.85689753
111polyol catabolic process (GO:0046174)2.84650752
112histone H3-K9 demethylation (GO:0033169)2.84106904
113mitotic sister chromatid cohesion (GO:0007064)2.82409994
114alanine transport (GO:0032328)2.80748682
115antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.79844000
116glandular epithelial cell development (GO:0002068)2.79495179
117chromatin silencing (GO:0006342)2.77235610
118GTP biosynthetic process (GO:0006183)2.76859972
119tyrosine phosphorylation of STAT protein (GO:0007260)2.76294919
120peptidyl-threonine dephosphorylation (GO:0035970)2.75221412
121positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.72679915
122regulation of cilium assembly (GO:1902017)2.72205569
123regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)2.72116792
124mitochondrion degradation (GO:0000422)2.61449587
125cilium organization (GO:0044782)2.61302441
126meiotic cell cycle process (GO:1903046)2.60423516
127axoneme assembly (GO:0035082)2.60024836
128membrane protein intracellular domain proteolysis (GO:0031293)2.57797810
129regulation of acrosome reaction (GO:0060046)2.57164891
130nucleosome disassembly (GO:0006337)2.55299708
131protein-DNA complex disassembly (GO:0032986)2.55299708
132cilium morphogenesis (GO:0060271)2.54768241
133cellular component assembly involved in morphogenesis (GO:0010927)2.54671181
134synapsis (GO:0007129)2.53954204
135cell redox homeostasis (GO:0045454)2.52373854
136microtubule-based movement (GO:0007018)2.52204256
137cilium assembly (GO:0042384)2.49484441
138peptidyl-glutamic acid modification (GO:0018200)2.48558994
139sperm motility (GO:0030317)14.2588679
140cell wall macromolecule metabolic process (GO:0044036)13.5916231
141cell wall macromolecule catabolic process (GO:0016998)13.5916231
142fusion of sperm to egg plasma membrane (GO:0007342)12.9512541
143acrosome reaction (GO:0007340)12.7201026
144acrosome assembly (GO:0001675)11.8706873
145sperm-egg recognition (GO:0035036)11.7209350
146binding of sperm to zona pellucida (GO:0007339)10.8237226
147cell-cell recognition (GO:0009988)10.4830143
148multicellular organism reproduction (GO:0032504)10.3383039

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse8.97521743
2EZH2_22144423_ChIP-Seq_EOC_Human4.08490958
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.70767837
4STAT6_21828071_ChIP-Seq_BEAS2B_Human3.13410349
5SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.11681877
6PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.88319646
7GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.71854887
8MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.52210246
9FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.44850935
10BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.43023339
11VDR_22108803_ChIP-Seq_LS180_Human2.41606267
12CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.29244541
13GATA1_26923725_Chip-Seq_HPCs_Mouse2.27693635
14CTBP1_25329375_ChIP-Seq_LNCAP_Human2.23383489
15ZNF274_21170338_ChIP-Seq_K562_Hela2.19851142
16* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse2.16479774
17EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human2.07650035
18FUS_26573619_Chip-Seq_HEK293_Human1.98017126
19GBX2_23144817_ChIP-Seq_PC3_Human1.96316547
20DROSHA_22980978_ChIP-Seq_HELA_Human1.95528394
21FLI1_27457419_Chip-Seq_LIVER_Mouse1.81450639
22KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.79786407
23ER_23166858_ChIP-Seq_MCF-7_Human1.79118434
24FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.76756537
25SOX2_22085726_ChIP-Seq_NPCs_Mouse1.76734670
26GATA3_21867929_ChIP-Seq_CD8_Mouse1.73135252
27AR_25329375_ChIP-Seq_VCAP_Human1.72981638
28STAT1_17558387_ChIP-Seq_HELA_Human1.70962332
29ERA_21632823_ChIP-Seq_H3396_Human1.68055308
30TAF15_26573619_Chip-Seq_HEK293_Human1.67937079
31NANOG_20526341_ChIP-Seq_ESCs_Human1.66949756
32GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.65675271
33NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.64637044
34TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.62244996
35* ELK4_26923725_Chip-Seq_MESODERM_Mouse1.58407200
36FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.56794305
37UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.55730172
38P300_19829295_ChIP-Seq_ESCs_Human1.52253086
39MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.52146088
40EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.52103172
41TAF2_19829295_ChIP-Seq_ESCs_Human1.51061709
42TOP2B_26459242_ChIP-Seq_MCF-7_Human1.50721097
43PCGF2_27294783_Chip-Seq_ESCs_Mouse1.50431693
44ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.49706324
45GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.49361768
46SUZ12_27294783_Chip-Seq_ESCs_Mouse1.49104478
47P53_21459846_ChIP-Seq_SAOS-2_Human1.48655879
48* MYC_19829295_ChIP-Seq_ESCs_Human1.48302325
49PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.45660430
50RAC3_21632823_ChIP-Seq_H3396_Human1.44286025
51CTCF_27219007_Chip-Seq_Bcells_Human1.44066708
52VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.43493920
53CBP_20019798_ChIP-Seq_JUKART_Human1.43464504
54IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.43464504
55WDR5_24793694_ChIP-Seq_LNCAP_Human1.42521468
56ETV2_25802403_ChIP-Seq_MESCs_Mouse1.41486522
57RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.41205219
58SMAD4_21741376_ChIP-Seq_EPCs_Human1.39902587
59GATA3_21878914_ChIP-Seq_MCF-7_Human1.38649440
60AR_21572438_ChIP-Seq_LNCaP_Human1.38458902
61TAL1_26923725_Chip-Seq_HPCs_Mouse1.37819580
62ARNT_22903824_ChIP-Seq_MCF-7_Human1.36564783
63KDM2B_26808549_Chip-Seq_REH_Human1.36094148
64LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.34056764
65* SMAD3_21741376_ChIP-Seq_ESCs_Human1.33814695
66E2F1_20622854_ChIP-Seq_HELA_Human1.33790840
67TP63_19390658_ChIP-ChIP_HaCaT_Human1.32682598
68SMAD3_21741376_ChIP-Seq_EPCs_Human1.32438299
69RAD21_21589869_ChIP-Seq_MESCs_Mouse1.32333172
70EZH2_27294783_Chip-Seq_ESCs_Mouse1.31939723
71TDRD3_21172665_ChIP-Seq_MCF-7_Human1.29235324
72ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.29168564
73TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.27481229
74GATA3_21867929_ChIP-Seq_TH1_Mouse1.27466001
75DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.27127911
76P300_27268052_Chip-Seq_Bcells_Human1.26746337
77* OCT4_20526341_ChIP-Seq_ESCs_Human1.25223892
78CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse1.25012462
79* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.24954098
80SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.23058271
81KAP1_22055183_ChIP-Seq_ESCs_Mouse1.22898993
82GF1_26923725_Chip-Seq_HPCs_Mouse1.22432159
83CBX2_27304074_Chip-Seq_ESCs_Mouse1.21156689
84* REST_21632747_ChIP-Seq_MESCs_Mouse1.20027067
85SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.19450036
86JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse1.19233576
87TET1_21451524_ChIP-Seq_MESCs_Mouse1.18825375
88* PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.18202600
89ERG_20517297_ChIP-Seq_VCAP_Human1.17943747
90FLI1_21867929_ChIP-Seq_TH2_Mouse1.17935799
91P68_20966046_ChIP-Seq_HELA_Human1.17426930
92SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.16737507
93NFE2_27457419_Chip-Seq_LIVER_Mouse1.16399438
94SMAD4_21799915_ChIP-Seq_A2780_Human1.16307172
95BMI1_23680149_ChIP-Seq_NPCS_Mouse1.16220643
96TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.15978759
97SOX2_19829295_ChIP-Seq_ESCs_Human1.15936618
98NANOG_19829295_ChIP-Seq_ESCs_Human1.15936618
99EZH2_27304074_Chip-Seq_ESCs_Mouse1.15527773
100STAT3_23295773_ChIP-Seq_U87_Human1.15371600
101TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14763106
102SPI1_26923725_Chip-Seq_HPCs_Mouse1.14472288
103ESET_19884257_ChIP-Seq_ESCs_Mouse1.14445692
104* CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.14329612
105PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.14236040
106AUTS2_25519132_ChIP-Seq_293T-REX_Human1.14141428
107RXRA_24833708_ChIP-Seq_LIVER_Mouse1.13588257
108PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.12817418
109MYC_27129775_Chip-Seq_CORNEA_Mouse1.11765033
110EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.10071761
111CTCF_20526341_ChIP-Seq_ESCs_Human1.09714537
112YY1_22570637_ChIP-Seq_MALME-3M_Human1.09709717
113SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.09256381
114CTBP2_25329375_ChIP-Seq_LNCAP_Human1.09218909
115PCGF2_27294783_Chip-Seq_NPCs_Mouse1.08904029
116GATA1_19941827_ChIP-Seq_MEL86_Mouse1.08628856
117OCT1_27270436_Chip-Seq_PROSTATE_Human1.08552706
118TP63_22573176_ChIP-Seq_HFKS_Human1.08398716
119RARA_24833708_ChIP-Seq_LIVER_Mouse1.08295580
120RBPJ_22232070_ChIP-Seq_NCS_Mouse1.08207311
121SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.07186018
122TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06826145
123POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.06826145
124EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.06202483
125KLF5_20875108_ChIP-Seq_MESCs_Mouse1.06062379
126SMC4_20622854_ChIP-Seq_HELA_Human1.05443722
127CEBPB_22108803_ChIP-Seq_LS180_Human1.05329485
128JARID2_20075857_ChIP-Seq_MESCs_Mouse1.05175713
129RUNX2_22187159_ChIP-Seq_PCA_Human1.04856623
130* PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.04820738
131SRY_22984422_ChIP-ChIP_TESTIS_Rat1.04115354
132MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.03520790
133PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.03416362
134* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.03222627
135SMAD4_21741376_ChIP-Seq_HESCs_Human1.02931365
136P63_20808887_ChIP-Seq_KERATINOCYTES_Human1.02917716
137SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.02887356
138BCOR_27268052_Chip-Seq_Bcells_Human1.02816612
139SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.02461947
140NFIB_24661679_ChIP-Seq_LUNG_Mouse1.02036449
141* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.01677084
142* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.01516976
143ELF1_20517297_ChIP-Seq_JURKAT_Human1.01167695
144CRX_20693478_ChIP-Seq_RETINA_Mouse1.00727136
145FLI1_21867929_ChIP-Seq_CD8_Mouse1.00636066
146REST_18959480_ChIP-ChIP_MESCs_Mouse1.00184670
147CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.00147045
148TCF4_23295773_ChIP-Seq_U87_Human0.99901343
149RUNX1_26923725_Chip-Seq_HPCs_Mouse0.99620608
150SOX11_22085726_ChIP-Seq_ESNs_Mouse0.99424611
151SUZ12_27294783_Chip-Seq_NPCs_Mouse0.99079609
152LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.98570995
153JARID2_20064375_ChIP-Seq_MESCs_Mouse0.98283827
154MTF2_20144788_ChIP-Seq_MESCs_Mouse0.97052582
155CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.95471888
156* NANOG_18555785_Chip-Seq_ESCs_Mouse0.92390361
157RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.91781359
158SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.90520271
159SOX2_21211035_ChIP-Seq_LN229_Human0.89623837
160PHF8_20622854_ChIP-Seq_HELA_Human0.89366612
161NFYB_21822215_ChIP-Seq_K562_Human0.88821976
162SMC3_22415368_ChIP-Seq_MEFs_Mouse0.88563396
163CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.88426464
164NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.88232164
165BCL6_27268052_Chip-Seq_Bcells_Human0.86647886
166KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.86389426

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive5.97897410
2MP0001929_abnormal_gametogenesis5.48744603
3MP0008877_abnormal_DNA_methylation3.41910859
4MP0005248_abnormal_Harderian_gland3.37776434
5MP0002161_abnormal_fertility/fecundity3.21061357
6MP0002210_abnormal_sex_determination3.20234200
7MP0010030_abnormal_orbit_morphology3.12562300
8MP0003880_abnormal_central_pattern3.11475410
9MP0004742_abnormal_vestibular_system3.06990427
10MP0005670_abnormal_white_adipose2.78081657
11MP0001145_abnormal_male_reproductive2.76425038
12MP0003718_maternal_effect2.42245949
13MP0000653_abnormal_sex_gland2.38366906
14MP0001348_abnormal_lacrimal_gland2.31703621
15MP0002249_abnormal_larynx_morphology2.25276315
16MP0005410_abnormal_fertilization16.8403141
17MP0001485_abnormal_pinna_reflex1.93872638
18MP0001968_abnormal_touch/_nociception1.76710412
19MP0003136_yellow_coat_color1.76692815
20MP0002272_abnormal_nervous_system1.75446247
21MP0003646_muscle_fatigue1.74022330
22MP0001486_abnormal_startle_reflex1.73343235
23MP0002160_abnormal_reproductive_system1.72125300
24MP0002653_abnormal_ependyma_morphology1.71842418
25MP0004233_abnormal_muscle_weight1.65705909
26MP0000613_abnormal_salivary_gland1.63369417
27MP0002735_abnormal_chemical_nociception1.54236680
28MP0005423_abnormal_somatic_nervous1.54160962
29MP0002067_abnormal_sensory_capabilities1.45736833
30MP0009745_abnormal_behavioral_response1.44302751
31MP0008569_lethality_at_weaning1.41295172
32MP0002822_catalepsy1.35874535
33MP0003635_abnormal_synaptic_transmissio1.31170556
34MP0005379_endocrine/exocrine_gland_phen1.29471204
35MP0004859_abnormal_synaptic_plasticity1.23018193
36MP0001440_abnormal_grooming_behavior1.18851337
37MP0010386_abnormal_urinary_bladder1.13956443
38MP0002557_abnormal_social/conspecific_i1.12874687
39MP0001905_abnormal_dopamine_level1.08001401
40MP0002282_abnormal_trachea_morphology1.06402194
41MP0001765_abnormal_ion_homeostasis1.05390966
42MP0005365_abnormal_bile_salt1.04601091
43MP0002572_abnormal_emotion/affect_behav1.03824148
44MP0001963_abnormal_hearing_physiology1.03490665
45MP0005623_abnormal_meninges_morphology1.03221529
46MP0000955_abnormal_spinal_cord1.02728350
47MP0000026_abnormal_inner_ear1.01421671
48MP0001986_abnormal_taste_sensitivity1.01137842
49MP0004885_abnormal_endolymph1.00767365
50MP0002064_seizures0.98854639
51MP0005647_abnormal_sex_gland0.97892916
52MP0001984_abnormal_olfaction0.97674093
53MP0006276_abnormal_autonomic_nervous0.97486677
54MP0002229_neurodegeneration0.97340676
55MP0003011_delayed_dark_adaptation0.95381171
56MP0004484_altered_response_of0.94922055
57MP0002132_abnormal_respiratory_system0.94878819
58MP0000678_abnormal_parathyroid_gland0.94327846
59MP0002063_abnormal_learning/memory/cond0.93216348
60MP0002234_abnormal_pharynx_morphology0.92779250
61MP0001666_abnormal_nutrient_absorption0.90868604
62MP0002734_abnormal_mechanical_nocicepti0.86723837
63MP0005595_abnormal_vascular_smooth0.84625630
64MP0005646_abnormal_pituitary_gland0.84366536
65MP0000579_abnormal_nail_morphology0.83486849
66MP0005083_abnormal_biliary_tract0.83056496
67MP0005395_other_phenotype0.82441515
68MP0005174_abnormal_tail_pigmentation0.82216479
69MP0001970_abnormal_pain_threshold0.81761174
70MP0009379_abnormal_foot_pigmentation0.81495163
71MP0002733_abnormal_thermal_nociception0.81466059
72MP0005389_reproductive_system_phenotype0.80454155
73MP0000230_abnormal_systemic_arterial0.77333634
74MP0004085_abnormal_heartbeat0.73672906
75MP0010329_abnormal_lipoprotein_level0.70863310
76MP0001501_abnormal_sleep_pattern0.69273496
77MP0005310_abnormal_salivary_gland0.68346504
78MP0003115_abnormal_respiratory_system0.67660416
79MP0004381_abnormal_hair_follicle0.67283553
80MP0005636_abnormal_mineral_homeostasis0.66759901
81MP0005075_abnormal_melanosome_morpholog0.66715884
82MP0009840_abnormal_foam_cell0.66651109
83MP0005645_abnormal_hypothalamus_physiol0.66476049
84MP0002184_abnormal_innervation0.66329261
85MP0002932_abnormal_joint_morphology0.65506880
86MP0009053_abnormal_anal_canal0.65098027
87MP0000778_abnormal_nervous_system0.64107060
88MP0000049_abnormal_middle_ear0.62874019
89MP0001764_abnormal_homeostasis0.62536395
90MP0002254_reproductive_system_inflammat0.61560079
91MP0008872_abnormal_physiological_respon0.59879798
92MP0004142_abnormal_muscle_tone0.57761118
93MP0006036_abnormal_mitochondrial_physio0.57321736
94MP0008995_early_reproductive_senescence0.56490291
95MP0008775_abnormal_heart_ventricle0.56172279
96MP0003632_abnormal_nervous_system0.56094488
97MP0002882_abnormal_neuron_morphology0.56018823
98MP0000467_abnormal_esophagus_morphology0.55377399
99MP0008058_abnormal_DNA_repair0.53523972
100MP0005085_abnormal_gallbladder_physiolo0.53111619
101MP0003959_abnormal_lean_body0.51667324
102MP0003329_amyloid_beta_deposits0.50732996
103MP0005084_abnormal_gallbladder_morpholo0.45394713
104MP0002139_abnormal_hepatobiliary_system0.45113940
105MP0000358_abnormal_cell_content/0.44809789
106MP0009046_muscle_twitch0.44722395
107MP0003868_abnormal_feces_composition0.44302863
108MP0001324_abnormal_eye_pigmentation0.43419973
109MP0003283_abnormal_digestive_organ0.42780548
110MP0005377_hearing/vestibular/ear_phenot0.42683053
111MP0003878_abnormal_ear_physiology0.42683053
112MP0004019_abnormal_vitamin_homeostasis0.42097061
113MP0005360_urolithiasis0.41900128
114MP0002693_abnormal_pancreas_physiology0.41384193
115MP0003699_abnormal_female_reproductive0.40875491
116MP0004036_abnormal_muscle_relaxation0.40727997
117MP0005220_abnormal_exocrine_pancreas0.40102615
118MP0002928_abnormal_bile_duct0.39841733
119MP0000534_abnormal_ureter_morphology0.39373493
120MP0005666_abnormal_adipose_tissue0.38333866
121MP0002269_muscular_atrophy0.36474614
122MP0001293_anophthalmia0.35723131
123MP0005397_hematopoietic_system_phenotyp0.35648101
124MP0001545_abnormal_hematopoietic_system0.35648101
125MP0004133_heterotaxia0.35030291
126MP0002736_abnormal_nociception_after0.34691942
127MP0000569_abnormal_digit_pigmentation0.34369917
128MP0003942_abnormal_urinary_system0.34369132
129MP0009278_abnormal_bone_marrow0.34113201
130MP0001873_stomach_inflammation0.33047828
131MP0006035_abnormal_mitochondrial_morpho0.31383824
132MP0005253_abnormal_eye_physiology0.27685476
133MP0004811_abnormal_neuron_physiology0.27327868
134MP0005551_abnormal_eye_electrophysiolog0.27060466
135MP0001664_abnormal_digestion0.25662869
136MP0002796_impaired_skin_barrier0.25128001
137MP0002118_abnormal_lipid_homeostasis0.24453455
138MP0008875_abnormal_xenobiotic_pharmacok0.24358469
139MP0002169_no_abnormal_phenotype0.24318503
140MP0002873_normal_phenotype0.23971584
141MP0004264_abnormal_extraembryonic_tissu0.23430108
142MP0003948_abnormal_gas_homeostasis0.23393330
143MP0003950_abnormal_plasma_membrane0.21855528
144MP0005391_vision/eye_phenotype0.21852198
145MP0009115_abnormal_fat_cell0.21575984
146MP0002295_abnormal_pulmonary_circulatio0.21503245
147MP0001119_abnormal_female_reproductive0.20497528
148MP0000604_amyloidosis0.19540126
149MP0005451_abnormal_body_composition0.19280950
150MP0003633_abnormal_nervous_system0.18633405
151MP0001661_extended_life_span0.17818010
152MP0005319_abnormal_enzyme/_coenzyme0.17011608
153MP0003861_abnormal_nervous_system0.16598917
154MP0002971_abnormal_brown_adipose0.16041995
155MP0003787_abnormal_imprinting0.15948744
156MP0002092_abnormal_eye_morphology0.14831537
157MP0000001_mammalian_phenotype0.14526280
158MP0002405_respiratory_system_inflammati0.14458672
159MP0002152_abnormal_brain_morphology0.13577854
160MP0003879_abnormal_hair_cell0.13315729
161MP0010094_abnormal_chromosome_stability0.13280378
162MP0003631_nervous_system_phenotype0.12200292
163MP0003252_abnormal_bile_duct0.12028918
164MP0003953_abnormal_hormone_level0.11953491
165MP0000462_abnormal_digestive_system0.11663064
166MP0001849_ear_inflammation0.11269619

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)9.23131706
2Abnormal respiratory motile cilium morphology (HP:0005938)9.14937472
3Abnormal respiratory epithelium morphology (HP:0012253)9.14937472
4Rhinitis (HP:0012384)7.60033166
5Chronic bronchitis (HP:0004469)7.40265214
6Infertility (HP:0000789)7.21262929
7Abnormal ciliary motility (HP:0012262)7.10693868
8Nasal polyposis (HP:0100582)6.37988121
9Severe visual impairment (HP:0001141)6.07061328
10Abnormality of the nasal mucosa (HP:0000433)5.21268988
11Male infertility (HP:0003251)4.73999239
12Attenuation of retinal blood vessels (HP:0007843)4.67745874
13Abnormal pancreas size (HP:0012094)4.62893655
14Bronchitis (HP:0012387)4.48496141
15Progressive cerebellar ataxia (HP:0002073)4.38201065
16Bronchiectasis (HP:0002110)4.32301050
17Bony spicule pigmentary retinopathy (HP:0007737)4.25311927
18Annular pancreas (HP:0001734)4.23708198
19Nephronophthisis (HP:0000090)4.16180548
20Chronic hepatic failure (HP:0100626)3.82835604
21Hyperkalemia (HP:0002153)3.81513884
22Abnormal spermatogenesis (HP:0008669)3.72339813
23Facial shape deformation (HP:0011334)3.58369562
24Potter facies (HP:0002009)3.58369562
25Bicornuate uterus (HP:0000813)3.41081525
26Abnormal rod and cone electroretinograms (HP:0008323)3.39099036
27Anophthalmia (HP:0000528)3.35273110
28Atonic seizures (HP:0010819)3.27455550
29Recurrent otitis media (HP:0000403)3.25926420
30Abnormality of the renal medulla (HP:0100957)3.18466271
31Postural instability (HP:0002172)3.16784078
32Myokymia (HP:0002411)3.14615488
33Recurrent sinusitis (HP:0011108)3.13076285
34Horizontal nystagmus (HP:0000666)3.12711029
35Hypoplastic ischia (HP:0003175)3.10533612
36Tubulointerstitial nephritis (HP:0001970)3.09756511
37Parkinsonism with favorable response to dopaminergic medication (HP:0002548)3.08340293
38Abnormality of macular pigmentation (HP:0008002)3.01061271
39Congenital sensorineural hearing impairment (HP:0008527)2.99665572
40Resting tremor (HP:0002322)2.94614780
41Tubular atrophy (HP:0000092)2.90268101
42Type II lissencephaly (HP:0007260)2.83923094
43Cone-rod dystrophy (HP:0000548)2.80240167
44Optic nerve hypoplasia (HP:0000609)2.76540974
45Febrile seizures (HP:0002373)2.74909516
46Polyuria (HP:0000103)2.70290399
47Abnormality of the ischium (HP:0003174)2.67614913
48Tubulointerstitial abnormality (HP:0001969)2.60154009
49Flat capital femoral epiphysis (HP:0003370)2.59460767
50Aplasia/Hypoplasia of the earlobes (HP:0009906)2.57774110
51Abnormality of dental color (HP:0011073)2.57439624
52Impulsivity (HP:0100710)2.56087257
53Recurrent bronchitis (HP:0002837)2.53983425
54Molar tooth sign on MRI (HP:0002419)2.52360427
55Abnormality of midbrain morphology (HP:0002418)2.52360427
56Pancreatic cysts (HP:0001737)2.48224935
57Pancreatic fibrosis (HP:0100732)2.47507892
58Cholecystitis (HP:0001082)2.45786763
59Abnormal gallbladder physiology (HP:0012438)2.45786763
60Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.44553165
61Azoospermia (HP:0000027)2.43960456
62Hyperthyroidism (HP:0000836)2.39719791
63Gaze-evoked nystagmus (HP:0000640)2.38480426
64Abnormality of potassium homeostasis (HP:0011042)2.37188138
65Renal Fanconi syndrome (HP:0001994)2.36892800
66Insulin-resistant diabetes mellitus (HP:0000831)2.31900052
67Gonadotropin excess (HP:0000837)2.30413894
68Dyschromatopsia (HP:0007641)2.27296586
69Amelogenesis imperfecta (HP:0000705)2.27267127
70Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.25438915
71Tubulointerstitial fibrosis (HP:0005576)2.25390207
72Medial flaring of the eyebrow (HP:0010747)2.25182308
73Action tremor (HP:0002345)2.20352671
74Hypophosphatemic rickets (HP:0004912)2.19908017
75Decreased central vision (HP:0007663)2.19804273
76Absence seizures (HP:0002121)2.16405452
77Focal motor seizures (HP:0011153)2.15395579
78Truncal obesity (HP:0001956)2.14857545
79Anterior segment dysgenesis (HP:0007700)2.14061077
80Aplasia/Hypoplasia of the sacrum (HP:0008517)2.08892860
81Congenital malformation of the right heart (HP:0011723)2.06283118
82Double outlet right ventricle (HP:0001719)2.06283118
83Choroideremia (HP:0001139)2.04996951
84Renovascular hypertension (HP:0100817)2.03296696
85Hypoplasia of the thymus (HP:0000778)2.00851553
86Dynein arm defect of respiratory motile cilia (HP:0012255)13.3407585
87Absent/shortened dynein arms (HP:0200106)13.3407585
88Respiratory insufficiency due to defective ciliary clearance (HP:0200073)12.8754234
89Progressive sensorineural hearing impairment (HP:0000408)1.99535382
90Enlarged epiphyses (HP:0010580)1.98636503
91Spastic tetraparesis (HP:0001285)1.94693526
92Genetic anticipation (HP:0003743)1.94063163
93Portal hypertension (HP:0001409)1.92973612
94Spastic paraparesis (HP:0002313)1.91343612
95Hypoalphalipoproteinemia (HP:0003233)1.89841197
96Inability to walk (HP:0002540)1.88867770
97Epileptic encephalopathy (HP:0200134)1.86819371
98Abnormality of the renal cortex (HP:0011035)1.86727930
99Stage 5 chronic kidney disease (HP:0003774)1.86259857
100Recurrent corneal erosions (HP:0000495)1.85407590
101Occipital encephalocele (HP:0002085)1.84966972
102Impaired smooth pursuit (HP:0007772)1.82343526
103Abnormality of renal excretion (HP:0011036)1.80605413
104Polydipsia (HP:0001959)1.80217556
105Abnormal drinking behavior (HP:0030082)1.80217556
106Decreased electroretinogram (ERG) amplitude (HP:0000654)1.79848044
107Photophobia (HP:0000613)1.79576763
108Confusion (HP:0001289)1.78493605
109Small intestinal stenosis (HP:0012848)1.76320034
110Duodenal stenosis (HP:0100867)1.76320034
111Hemorrhage of the eye (HP:0011885)1.73875156
112Hypoplasia of the capital femoral epiphysis (HP:0003090)1.73575253
113Postaxial foot polydactyly (HP:0001830)1.68997644
114Heterotopia (HP:0002282)1.61914670
115Congenital hepatic fibrosis (HP:0002612)1.60399988
116Neurofibrillary tangles (HP:0002185)1.52554924
117Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.48695377
118Absent epiphyses (HP:0010577)1.48695377
119Renal dysplasia (HP:0000110)1.48443463
120Bell-shaped thorax (HP:0001591)1.44517859
121Abnormality of permanent molar morphology (HP:0011071)1.44373955
122Abnormality of the dental root (HP:0006486)1.44373955
123Taurodontia (HP:0000679)1.44373955
124Oculomotor apraxia (HP:0000657)1.44277637
125Short ribs (HP:0000773)1.43672739
126Aplasia/Hypoplasia of the lens (HP:0008063)1.43563421
127Bile duct proliferation (HP:0001408)1.43174024
128Abnormal biliary tract physiology (HP:0012439)1.43174024
129Asymmetric septal hypertrophy (HP:0001670)1.41368106
130Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.40776536
131Vascular calcification (HP:0004934)1.40080974
132Easy fatigability (HP:0003388)1.39281715
133Short femoral neck (HP:0100864)1.38919322
134Abnormal urine output (HP:0012590)1.38469137
135Cerebellar dysplasia (HP:0007033)1.37577106
136Abnormality of dentin (HP:0010299)1.37083484
137Abnormality of the dental pulp (HP:0006479)1.33675754
138Postaxial hand polydactyly (HP:0001162)1.33088264
139Fibular hypoplasia (HP:0003038)1.32961626
140Exercise-induced myalgia (HP:0003738)1.32172263
141Abnormality of molar (HP:0011077)1.32085727
142Abnormality of molar morphology (HP:0011070)1.32085727
143Bundle branch block (HP:0011710)1.31524534
144Myoglobinuria (HP:0002913)1.28369155
145Fatigable weakness (HP:0003473)1.27800174
146Abnormality of the neuromuscular junction (HP:0003398)1.27800174
147Transposition of the great arteries (HP:0001669)1.26616065
148Abnormal connection of the cardiac segments (HP:0011545)1.26616065
149Abnormal ventriculo-arterial connection (HP:0011563)1.26616065
150Deformed sella turcica (HP:0002681)1.25003895
151Cardiovascular calcification (HP:0011915)1.23926286
152Retinal dysplasia (HP:0007973)1.23361435
153Loss of speech (HP:0002371)1.20430422
154Cerebral inclusion bodies (HP:0100314)1.19297306
155Absent frontal sinuses (HP:0002688)1.18461966
156Nephropathy (HP:0000112)1.18184988
157Constricted visual fields (HP:0001133)1.18115028
158Short thorax (HP:0010306)1.17231571
159Sensory axonal neuropathy (HP:0003390)1.17112353
160Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)1.16708060
161Facial cleft (HP:0002006)1.16318792
162Hypercholesterolemia (HP:0003124)1.15265932
163Retinal atrophy (HP:0001105)1.15116550
164Flattened epiphyses (HP:0003071)1.14842714
165Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.14567398

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK37.56369032
2PDK47.56369032
3TESK17.41303106
4PRKD35.22578043
5PDK24.97578517
6ICK4.81638498
7DDR23.92958904
8PLK23.18474746
9INSRR2.93474867
10MAP4K22.83752383
11PTK2B2.31439859
12WNK42.16390510
13STK392.11382130
14STK382.07931599
15MAP3K111.92785133
16DYRK1B1.69335636
17NEK21.58628662
18PNCK1.41668143
19BMPR1B1.38973863
20PDK11.36067166
21TNIK1.35600221
22MST1R1.31377800
23BRD41.23201825
24MAPK151.13445127
25ADRBK21.08427898
26TAOK21.07986982
27GRK51.06754693
28MAP3K91.06583272
29TAOK31.02216414
30STK38L0.94793853
31PDPK10.93331125
32DYRK30.92508996
33SIK20.88577848
34IRAK10.87349697
35TYRO30.85985908
36EEF2K0.84666953
37CAMKK20.84568525
38MAP2K20.80967129
39DYRK1A0.77206089
40CDK70.76850124
41DYRK20.74940293
42AKT30.74700117
43KIT0.73476929
44MAP3K40.72420902
45STK30.72021623
46WNK10.71382767
47OXSR10.70093788
48CAMK10.69955766
49PASK0.68670916
50MAP2K60.67137461
51DAPK20.66188199
52ACVR1B0.66026748
53RIPK40.65045402
54PRKAA20.64233957
55MARK10.63400462
56PINK10.59587699
57NTRK30.57638706
58TTK0.56478967
59IRAK20.55851356
60CASK0.54526618
61MAP3K10.54023525
62ARAF0.53669513
63CHEK20.52417772
64MUSK0.50393970
65CCNB10.49450013
66TAF10.47707497
67PTK60.47202495
68TAOK10.46656618
69ROCK10.46043838
70TESK20.45843979
71CSNK1G20.44138862
72CAMK1D0.43781199
73PRKCE0.43705330
74PAK20.42264382
75NTRK20.40683156
76PRKCG0.39122650
77MAP3K100.38794592
78MAPK10.37375135
79MAP3K120.35277982
80SGK10.34910876
81LMTK20.34909403
82MAPKAPK50.33940387
83PAK10.33824634
84UHMK10.31467426
85CDK20.30991350
86CAMKK10.28210861
87BCKDK0.28190216
88NUAK10.27780015
89FRK0.27654918
90CHEK10.27142959
91CAMK40.27041054
92MAP2K70.26570402
93FLT30.26251436
94CAMK1G0.25930062
95MINK10.25623845
96SGK2230.25358606
97SGK4940.25358606
98MARK20.25125771
99TGFBR10.24468766
100NEK60.23905541
101RPS6KA60.23901081
102MTOR0.22797275
103MAPK140.22603366
104MAP3K70.22197682
105MAP3K80.22182613
106ATM0.21892234
107RPS6KA10.21435671
108GRK10.21338738
109PRKAA10.21234353
110RPS6KB10.19812472
111MAPKAPK30.18706104
112PRKCQ0.17803709
113PRKCZ0.16609973
114PIM10.15765010
115STK100.15316272
116PRKG20.14780640
117BRAF0.14756058
118ATR0.14306768
119CDK30.10735159
120CDK150.10569366
121PKN10.09538870
122CSF1R0.09291120
123CSNK2A10.09195542
124ZAP700.08350881
125CDK11A0.08143028
126PAK40.07801071
127CDK180.07758215
128STK240.07505174
129PLK10.07376003
130PRKCD0.05350631
131CAMK2A0.04802483
132PRKACG0.03405453
133PRKCA0.03069533
134GSK3B0.02519203
135MAP3K50.02076378
136CDK40.01907809
137PRKG10.01767461
138CLK10.01755430
139CDK140.01570932
140PLK40.00736706
141PDGFRB0.00434187
142PIK3CG0.00119165
143MARK3-0.0379849
144BRSK2-0.0369454
145BRSK1-0.0352649
146PRKACB-0.0352500
147CSK-0.0322401
148MAP3K3-0.0266361
149CDK1-0.0251123
150PRKACA-0.0237201
151AURKA-0.0198732
152STK11-0.0134098
153CSNK2A2-0.0132751
154ERN1-0.0044399
155PRKCB-0.0041894
156CSNK1D-0.0035365
157MAPK8-0.0019140

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000725.58193289
2Fatty acid biosynthesis_Homo sapiens_hsa000614.37206269
3Glycolysis / Gluconeogenesis_Homo sapiens_hsa000104.12687366
4Vitamin B6 metabolism_Homo sapiens_hsa007503.57664741
5alpha-Linolenic acid metabolism_Homo sapiens_hsa005923.48931229
6Linoleic acid metabolism_Homo sapiens_hsa005913.41821043
7Pyruvate metabolism_Homo sapiens_hsa006203.26874267
8Nitrogen metabolism_Homo sapiens_hsa009103.17289749
9Olfactory transduction_Homo sapiens_hsa047402.99583244
10Propanoate metabolism_Homo sapiens_hsa006402.92379312
11Fat digestion and absorption_Homo sapiens_hsa049752.72378616
12Butanoate metabolism_Homo sapiens_hsa006502.67874592
13Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.64725881
14Glycerolipid metabolism_Homo sapiens_hsa005612.42237486
15Glucagon signaling pathway_Homo sapiens_hsa049222.34220223
16Carbohydrate digestion and absorption_Homo sapiens_hsa049732.29875338
17Protein processing in endoplasmic reticulum_Homo sapiens_hsa041412.28371989
18Selenocompound metabolism_Homo sapiens_hsa004502.26518353
19Nicotine addiction_Homo sapiens_hsa050332.16888498
20Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.14536563
21Pancreatic secretion_Homo sapiens_hsa049722.08469619
22Morphine addiction_Homo sapiens_hsa050322.03590902
23Neuroactive ligand-receptor interaction_Homo sapiens_hsa040802.01984488
24Basal transcription factors_Homo sapiens_hsa030221.93763780
25Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.76204693
26Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.76077659
27GABAergic synapse_Homo sapiens_hsa047271.67469197
28Glycerophospholipid metabolism_Homo sapiens_hsa005641.67110868
29PPAR signaling pathway_Homo sapiens_hsa033201.64312734
30Sulfur relay system_Homo sapiens_hsa041221.61887416
31Ether lipid metabolism_Homo sapiens_hsa005651.57705047
32Amphetamine addiction_Homo sapiens_hsa050311.57562855
33Protein digestion and absorption_Homo sapiens_hsa049741.54888961
34Long-term depression_Homo sapiens_hsa047301.54363704
35Glutamatergic synapse_Homo sapiens_hsa047241.52992271
36Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.48939397
37Fructose and mannose metabolism_Homo sapiens_hsa000511.48339813
38Fatty acid degradation_Homo sapiens_hsa000711.40777939
39Mineral absorption_Homo sapiens_hsa049781.38994615
40Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.37307437
41Glutathione metabolism_Homo sapiens_hsa004801.33777751
42Phototransduction_Homo sapiens_hsa047441.33754588
43Fatty acid metabolism_Homo sapiens_hsa012121.31450787
44Aldosterone synthesis and secretion_Homo sapiens_hsa049251.30399167
45Cardiac muscle contraction_Homo sapiens_hsa042601.26164950
46Oocyte meiosis_Homo sapiens_hsa041141.25055375
47Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.23922640
48Serotonergic synapse_Homo sapiens_hsa047261.20277005
49Cysteine and methionine metabolism_Homo sapiens_hsa002701.20187001
50Pentose phosphate pathway_Homo sapiens_hsa000301.19047378
51Glycosaminoglycan degradation_Homo sapiens_hsa005311.17050330
52Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.17021519
53Carbon metabolism_Homo sapiens_hsa012001.14698985
54Arachidonic acid metabolism_Homo sapiens_hsa005901.05175717
55Chemical carcinogenesis_Homo sapiens_hsa052041.05116989
56Antigen processing and presentation_Homo sapiens_hsa046121.02707390
57Renin secretion_Homo sapiens_hsa049241.01807399
58Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.98066357
59Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.95753029
60Dorso-ventral axis formation_Homo sapiens_hsa043200.92257661
61Fanconi anemia pathway_Homo sapiens_hsa034600.91887896
62Collecting duct acid secretion_Homo sapiens_hsa049660.90393357
63Oxidative phosphorylation_Homo sapiens_hsa001900.89945710
64Cholinergic synapse_Homo sapiens_hsa047250.87176932
65Tryptophan metabolism_Homo sapiens_hsa003800.86736749
66Purine metabolism_Homo sapiens_hsa002300.86690744
67Hedgehog signaling pathway_Homo sapiens_hsa043400.85169152
68Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.84038766
69Parkinsons disease_Homo sapiens_hsa050120.82482123
70Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.82429294
71Maturity onset diabetes of the young_Homo sapiens_hsa049500.82159151
72Insulin secretion_Homo sapiens_hsa049110.81840104
73Type I diabetes mellitus_Homo sapiens_hsa049400.80702662
74Type II diabetes mellitus_Homo sapiens_hsa049300.80451582
75Huntingtons disease_Homo sapiens_hsa050160.80356543
76Arginine and proline metabolism_Homo sapiens_hsa003300.79898615
77Dopaminergic synapse_Homo sapiens_hsa047280.79658734
78Autoimmune thyroid disease_Homo sapiens_hsa053200.79458865
79Biosynthesis of amino acids_Homo sapiens_hsa012300.75887898
80Retinol metabolism_Homo sapiens_hsa008300.75859110
81Adipocytokine signaling pathway_Homo sapiens_hsa049200.73266582
82Systemic lupus erythematosus_Homo sapiens_hsa053220.69416853
83Renin-angiotensin system_Homo sapiens_hsa046140.69330240
84Bile secretion_Homo sapiens_hsa049760.67338185
85Tyrosine metabolism_Homo sapiens_hsa003500.66540485
86Alzheimers disease_Homo sapiens_hsa050100.65788191
87Estrogen signaling pathway_Homo sapiens_hsa049150.61525960
88cGMP-PKG signaling pathway_Homo sapiens_hsa040220.60802185
89Thyroid hormone synthesis_Homo sapiens_hsa049180.60586478
90Peroxisome_Homo sapiens_hsa041460.59726139
91Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.59536409
92Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.59379896
93Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.59179619
94Long-term potentiation_Homo sapiens_hsa047200.58684897
95Allograft rejection_Homo sapiens_hsa053300.55604044
96Calcium signaling pathway_Homo sapiens_hsa040200.52937348
97Legionellosis_Homo sapiens_hsa051340.51971911
98Graft-versus-host disease_Homo sapiens_hsa053320.50725983
99mRNA surveillance pathway_Homo sapiens_hsa030150.48754622
100Oxytocin signaling pathway_Homo sapiens_hsa049210.48479106
101beta-Alanine metabolism_Homo sapiens_hsa004100.47996623
102Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.45809210
103Alcoholism_Homo sapiens_hsa050340.45445230
104African trypanosomiasis_Homo sapiens_hsa051430.45441298
105MAPK signaling pathway_Homo sapiens_hsa040100.44051307
106Central carbon metabolism in cancer_Homo sapiens_hsa052300.43801443
107Metabolic pathways_Homo sapiens_hsa011000.43457296
108Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.43329206
109Salivary secretion_Homo sapiens_hsa049700.43033208
110Phenylalanine metabolism_Homo sapiens_hsa003600.40934293
111Vascular smooth muscle contraction_Homo sapiens_hsa042700.40697841
112Histidine metabolism_Homo sapiens_hsa003400.40495180
113ABC transporters_Homo sapiens_hsa020100.39915175
114Sulfur metabolism_Homo sapiens_hsa009200.38567446
115AMPK signaling pathway_Homo sapiens_hsa041520.38085942
116Regulation of autophagy_Homo sapiens_hsa041400.37014565
117Inositol phosphate metabolism_Homo sapiens_hsa005620.36825082
118Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.36450106
119Synaptic vesicle cycle_Homo sapiens_hsa047210.34889476
120Endocytosis_Homo sapiens_hsa041440.34868858
121RNA transport_Homo sapiens_hsa030130.34145998
122Cocaine addiction_Homo sapiens_hsa050300.33516702
123Non-small cell lung cancer_Homo sapiens_hsa052230.32218393
124VEGF signaling pathway_Homo sapiens_hsa043700.32008210
125Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.31769807
126Phosphatidylinositol signaling system_Homo sapiens_hsa040700.30102196
127Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.29029114
128Gastric acid secretion_Homo sapiens_hsa049710.27060517
129N-Glycan biosynthesis_Homo sapiens_hsa005100.25778219
130Vitamin digestion and absorption_Homo sapiens_hsa049770.24478038
131cAMP signaling pathway_Homo sapiens_hsa040240.23561652
132Thyroid hormone signaling pathway_Homo sapiens_hsa049190.19658033
133Pentose and glucuronate interconversions_Homo sapiens_hsa000400.18176527
134Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.17284910
135Pyrimidine metabolism_Homo sapiens_hsa002400.16799777
136Basal cell carcinoma_Homo sapiens_hsa052170.14387134
137Primary bile acid biosynthesis_Homo sapiens_hsa001200.11408959
138Circadian entrainment_Homo sapiens_hsa047130.11003118
139B cell receptor signaling pathway_Homo sapiens_hsa046620.09473576
140Wnt signaling pathway_Homo sapiens_hsa043100.07227119
141Taste transduction_Homo sapiens_hsa047420.06964364
142Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.06390712
143Steroid hormone biosynthesis_Homo sapiens_hsa001400.05359885
144Viral carcinogenesis_Homo sapiens_hsa052030.03358900

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