BAZ2A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)5.67176063
2nuclear pore organization (GO:0006999)5.47113533
3pre-miRNA processing (GO:0031054)5.16837512
4negative regulation of histone methylation (GO:0031061)4.69744055
5negative regulation of erythrocyte differentiation (GO:0045647)4.58181112
6mitotic sister chromatid cohesion (GO:0007064)4.47020005
7pore complex assembly (GO:0046931)4.39859228
8regulation of histone H3-K9 methylation (GO:0051570)4.33939996
9positive regulation of gamma-delta T cell activation (GO:0046645)4.25540116
10regulation of RNA export from nucleus (GO:0046831)4.16951627
11regulation of posttranscriptional gene silencing (GO:0060147)4.14547713
12regulation of gene silencing by miRNA (GO:0060964)4.14547713
13regulation of gene silencing by RNA (GO:0060966)4.14547713
14mitotic nuclear envelope disassembly (GO:0007077)3.82426118
15gene silencing by RNA (GO:0031047)3.81630183
16histone H2A monoubiquitination (GO:0035518)3.64867067
17histone H4-K12 acetylation (GO:0043983)3.64432153
18response to muramyl dipeptide (GO:0032495)3.62763906
19membrane disassembly (GO:0030397)3.62028180
20nuclear envelope disassembly (GO:0051081)3.62028180
21regulation of gamma-delta T cell activation (GO:0046643)3.58337523
22protein localization to kinetochore (GO:0034501)3.52803465
23cytoplasmic mRNA processing body assembly (GO:0033962)3.51123901
24mitotic chromosome condensation (GO:0007076)3.50986218
25NLS-bearing protein import into nucleus (GO:0006607)3.48447846
26regulation of gamma-delta T cell differentiation (GO:0045586)3.46559415
273-UTR-mediated mRNA stabilization (GO:0070935)3.46395019
28trophectodermal cell differentiation (GO:0001829)3.45847683
29regulation of NFAT protein import into nucleus (GO:0051532)3.42405742
30positive regulation of chromosome segregation (GO:0051984)3.39183981
31protein localization to chromosome, centromeric region (GO:0071459)3.38719896
32positive regulation of mitotic sister chromatid separation (GO:1901970)3.35618310
33positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.35618310
34positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.35618310
35modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.34931511
36positive regulation by organism of defense response of other organism involved in symbiotic interact3.34931511
37modulation by symbiont of host immune response (GO:0052553)3.34931511
38positive regulation by symbiont of host defense response (GO:0052509)3.34931511
39modulation by symbiont of host defense response (GO:0052031)3.34931511
40modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.34931511
41negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.33396552
42negative regulation of cell killing (GO:0031342)3.33396552
43* gene silencing (GO:0016458)3.33233589
44regulation of nucleobase-containing compound transport (GO:0032239)3.32510965
45regulation of sister chromatid cohesion (GO:0007063)3.32240071
46monoubiquitinated protein deubiquitination (GO:0035520)3.28929430
47histone H3-K9 demethylation (GO:0033169)3.27613112
48histone H3-K4 methylation (GO:0051568)3.26142451
49antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.25644249
50RNA stabilization (GO:0043489)3.24630356
51mRNA stabilization (GO:0048255)3.24630356
52mannose metabolic process (GO:0006013)3.23374606
53positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.22367886
54mitotic sister chromatid segregation (GO:0000070)3.20968696
55piRNA metabolic process (GO:0034587)3.19543898
56determination of adult lifespan (GO:0008340)3.19238441
57sister chromatid segregation (GO:0000819)3.18540734
58regulation of hippo signaling (GO:0035330)3.17394748
59thymic T cell selection (GO:0045061)3.15327886
60regulation of gene silencing (GO:0060968)3.13513936
61regulation of translational fidelity (GO:0006450)3.13355254
62antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.12008963
63DNA replication-dependent nucleosome assembly (GO:0006335)3.11819947
64DNA replication-dependent nucleosome organization (GO:0034723)3.11819947
65negative regulation of histone modification (GO:0031057)3.10679787
66positive regulation of gene expression, epigenetic (GO:0045815)3.09493227
67negative regulation of chromatin modification (GO:1903309)3.08711762
68regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.08555126
69DNA duplex unwinding (GO:0032508)3.08539915
70regulation of mitotic spindle organization (GO:0060236)3.08250919
71DNA geometric change (GO:0032392)3.08165819
72synaptonemal complex assembly (GO:0007130)3.07042222
73embryonic process involved in female pregnancy (GO:0060136)3.06716911
74positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003603.06389748
75histone lysine demethylation (GO:0070076)3.06017496
76spindle assembly involved in mitosis (GO:0090307)3.06014928
77regulation of spindle organization (GO:0090224)3.05573566
78intracellular estrogen receptor signaling pathway (GO:0030520)3.04553491
79positive regulation of SMAD protein import into nucleus (GO:0060391)3.02182847
80antigen processing and presentation of endogenous antigen (GO:0019883)3.01478197
81histone H3-K4 trimethylation (GO:0080182)3.00935421
82negative thymic T cell selection (GO:0045060)2.97549592
83regulation of histone methylation (GO:0031060)2.96957543
84histone H4-K5 acetylation (GO:0043981)2.96863959
85histone H4-K8 acetylation (GO:0043982)2.96863959
86regulation of meiosis I (GO:0060631)2.96236328
87histone demethylation (GO:0016577)2.95590645
88regulation of protein polyubiquitination (GO:1902914)2.94934193
89dosage compensation (GO:0007549)2.94044592
90histone H3-K36 demethylation (GO:0070544)2.93682660
91nuclear envelope organization (GO:0006998)2.92889526
92sister chromatid cohesion (GO:0007062)2.92597118
93intestinal epithelial cell development (GO:0060576)2.91415440
94histone H4-K16 acetylation (GO:0043984)2.91178425
95response to laminar fluid shear stress (GO:0034616)2.89424533
96microtubule cytoskeleton organization involved in mitosis (GO:1902850)2.88118037
97cellular response to virus (GO:0098586)2.87486045
98regulation of chromatin silencing (GO:0031935)2.86918588
99positive regulation of histone deacetylation (GO:0031065)2.86413797
100positive thymic T cell selection (GO:0045059)2.85789234
101B cell receptor signaling pathway (GO:0050853)2.85661876
102nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.84363558
103glucocorticoid receptor signaling pathway (GO:0042921)2.81937113
104* heterochromatin organization (GO:0070828)2.80504053
105T cell selection (GO:0045058)2.80125626
106antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.78850443
107regulation of chromatin binding (GO:0035561)2.78445236
108response to peptidoglycan (GO:0032494)2.77965641
109modulation by virus of host process (GO:0019054)2.77511571
110chromosome condensation (GO:0030261)2.77508464
111protein localization to chromosome (GO:0034502)2.76455786
112inner cell mass cell proliferation (GO:0001833)2.76215620
113paraxial mesoderm development (GO:0048339)2.74672582
114detection of other organism (GO:0098543)2.74606878
115synaptonemal complex organization (GO:0070193)2.74121758
116negative regulation of gene silencing (GO:0060969)2.73765094
117detection of bacterium (GO:0016045)2.72905155
118negative T cell selection (GO:0043383)2.71925864
119mRNA transport (GO:0051028)2.70174550
120* chromatin assembly (GO:0031497)2.69737650
121peptidyl-lysine dimethylation (GO:0018027)2.69609294
122modulation by symbiont of host cellular process (GO:0044068)2.69432105
123DNA unwinding involved in DNA replication (GO:0006268)2.68962925
124DNA conformation change (GO:0071103)2.68930841
125germinal center formation (GO:0002467)2.68734018
126protein dealkylation (GO:0008214)2.67939196
127protein demethylation (GO:0006482)2.67939196
128nucleus organization (GO:0006997)2.67159411
129regulation of B cell receptor signaling pathway (GO:0050855)2.66245958
130regulation of telomere maintenance via telomerase (GO:0032210)2.64854881
131DNA packaging (GO:0006323)2.64728563
132regulation of histone H3-K27 methylation (GO:0061085)2.63987699
133mitotic metaphase plate congression (GO:0007080)2.63949108
134regulation of helicase activity (GO:0051095)2.63867044
135male meiosis (GO:0007140)2.63448834
136regulation of ARF protein signal transduction (GO:0032012)2.62970310
137spliceosomal tri-snRNP complex assembly (GO:0000244)2.62857856
138negative regulation of retinoic acid receptor signaling pathway (GO:0048387)2.62443058
139DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla2.61524841
140peptidyl-lysine trimethylation (GO:0018023)2.61343118
141cell-substrate adherens junction assembly (GO:0007045)2.60075238
142focal adhesion assembly (GO:0048041)2.60075238
143macrophage activation involved in immune response (GO:0002281)2.59678355
144positive regulation of transcription from RNA polymerase III promoter (GO:0045945)2.57762090
145cellular extravasation (GO:0045123)2.56982990
146positive regulation of Rap GTPase activity (GO:0032854)2.53365501
147antigen processing and presentation via MHC class Ib (GO:0002475)2.53116748
148positive regulation of Cdc42 GTPase activity (GO:0043089)2.51835597
149regulation of type I interferon-mediated signaling pathway (GO:0060338)2.50257447
150leukocyte aggregation (GO:0070486)2.47905279
151positive T cell selection (GO:0043368)2.47039949
152response to interleukin-15 (GO:0070672)2.45544392
153cellular response to epidermal growth factor stimulus (GO:0071364)2.44181707
154peptidyl-threonine phosphorylation (GO:0018107)2.44167411
155positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.42820216
156* histone lysine methylation (GO:0034968)2.42443508
157corticosteroid receptor signaling pathway (GO:0031958)2.42321227
158negative regulation of toll-like receptor signaling pathway (GO:0034122)2.42210011
159JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.41625821
160regulation of necroptotic process (GO:0060544)2.40878776
161adherens junction assembly (GO:0034333)2.40870101
162regulation of interferon-beta biosynthetic process (GO:0045357)2.39895177
163negative regulation of myotube differentiation (GO:0010832)2.38570570
164response to epidermal growth factor (GO:0070849)2.38075515
165response to host (GO:0075136)2.38022153
166response to host defenses (GO:0052200)2.38022153
167response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.38022153
168activation of Rac GTPase activity (GO:0032863)2.36232143
169regulation of ARF GTPase activity (GO:0032312)2.35639263
170N-terminal protein amino acid acetylation (GO:0006474)2.34863613
171stress granule assembly (GO:0034063)2.34586316
172poly(A)+ mRNA export from nucleus (GO:0016973)2.34387054
173positive regulation of protein deacetylation (GO:0090312)2.34074546

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.62600097
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.91767163
3EGR1_19374776_ChIP-ChIP_THP-1_Human3.66149231
4MYC_22102868_ChIP-Seq_BL_Human3.24851367
5NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.70655506
6E2F4_17652178_ChIP-ChIP_JURKAT_Human2.59459876
7MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.45311099
8KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.39431268
9KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.39431268
10KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.39431268
11FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.39385894
12* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.39339632
13SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.33432641
14VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.18512083
15SALL1_21062744_ChIP-ChIP_HESCs_Human2.16336431
16VDR_24763502_ChIP-Seq_THP-1_Human2.04720452
17* MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.00241350
18IRF8_22096565_ChIP-ChIP_GC-B_Human1.99338307
19FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.93777559
20LXR_22292898_ChIP-Seq_THP-1_Human1.89766462
21* TCF7_22412390_ChIP-Seq_EML_Mouse1.89116832
22STAT6_21828071_ChIP-Seq_BEAS2B_Human1.88935250
23SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.87867095
24THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.86165264
25KDM2B_26808549_Chip-Seq_K562_Human1.85777600
26ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.83869468
27SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.81515591
28POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.80634325
29MYC_19079543_ChIP-ChIP_MESCs_Mouse1.80107408
30NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.79739475
31* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.78523413
32VDR_21846776_ChIP-Seq_THP-1_Human1.76016999
33* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.74663416
34TP63_19390658_ChIP-ChIP_HaCaT_Human1.73794469
35SCL_19346495_ChIP-Seq_HPC-7_Human1.73123349
36E2F1_21310950_ChIP-Seq_MCF-7_Human1.73079727
37* KDM2B_26808549_Chip-Seq_DND41_Human1.69212535
38MYB_21317192_ChIP-Seq_ERMYB_Mouse1.67036210
39SPI1_23127762_ChIP-Seq_K562_Human1.65007098
40* RUNX1_22412390_ChIP-Seq_EML_Mouse1.64938086
41NANOG_18555785_ChIP-Seq_MESCs_Mouse1.61172010
42CIITA_25753668_ChIP-Seq_RAJI_Human1.59694831
43STAT3_1855785_ChIP-Seq_MESCs_Mouse1.59401060
44TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.58953465
45* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.58135208
46* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.57013424
47SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.56411014
48STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.54512230
49CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.53989037
50AR_21909140_ChIP-Seq_LNCAP_Human1.51000046
51MYC_18555785_ChIP-Seq_MESCs_Mouse1.50004893
52NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.49886216
53STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.49115608
54* UTX_26944678_Chip-Seq_JUKART_Human1.46836929
55KDM5A_27292631_Chip-Seq_BREAST_Human1.45931872
56GATA1_19941826_ChIP-Seq_K562_Human1.44983510
57NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.44394029
58POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.43530607
59RUNX_20019798_ChIP-Seq_JUKART_Human1.41888666
60MAF_26560356_Chip-Seq_TH1_Human1.39479948
61MYB_26560356_Chip-Seq_TH1_Human1.39223557
62GATA1_19941827_ChIP-Seq_MEL_Mouse1.38012891
63TP63_17297297_ChIP-ChIP_HaCaT_Human1.37376831
64KLF4_18555785_ChIP-Seq_MESCs_Mouse1.37105138
65ESR2_21235772_ChIP-Seq_MCF-7_Human1.36243206
66TCF3_18692474_ChIP-Seq_MEFs_Mouse1.36172104
67TCF3_18692474_ChIP-Seq_MESCs_Mouse1.34678924
68ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.32799883
69* NANOG_21062744_ChIP-ChIP_HESCs_Human1.32749128
70KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.31880463
71GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.30954449
72MYCN_18555785_ChIP-Seq_MESCs_Mouse1.30503492
73NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.29369812
74CREB1_26743006_Chip-Seq_LNCaP_Human1.28907031
75WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.28085743
76ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.27497214
77* NCOR1_26117541_ChIP-Seq_K562_Human1.26187196
78* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.26096573
79IRF8_27001747_Chip-Seq_BMDM_Mouse1.26052124
80SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.25485807
81GATA1_22383799_ChIP-Seq_G1ME_Mouse1.25140905
82PKCTHETA_26484144_Chip-Seq_BREAST_Human1.24189177
83* ZFP281_27345836_Chip-Seq_ESCs_Mouse1.24082253
84ZNF263_19887448_ChIP-Seq_K562_Human1.23786047
85* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.23426595
86MYB_26560356_Chip-Seq_TH2_Human1.22596963
87* TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.22433866
88RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.21979273
89STAT4_19710469_ChIP-ChIP_TH1__Mouse1.21541962
90CLOCK_20551151_ChIP-Seq_293T_Human1.21473587
91* CTCF_27219007_Chip-Seq_ERYTHROID_Human1.21157054
92MYC_19030024_ChIP-ChIP_MESCs_Mouse1.20648816
93NELFA_20434984_ChIP-Seq_ESCs_Mouse1.17906506
94* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.17401511
95KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.16136212
96KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.15761789
97* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.15277323
98KDM2B_26808549_Chip-Seq_SUP-B15_Human1.15134908
99* ELK3_25401928_ChIP-Seq_HUVEC_Human1.14804972
100SMC4_20622854_ChIP-Seq_HELA_Human1.14299891
101POU5F1_16518401_ChIP-PET_MESCs_Mouse1.14091133
102SPI1_23547873_ChIP-Seq_NB4_Human1.12384253
103* CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.11459856
104STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.10439800
105SOX2_27498859_Chip-Seq_STOMACH_Mouse1.10199586
106EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.09836204
107TFEB_21752829_ChIP-Seq_HELA_Human1.09445256
108* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.07919408
109DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.07315437
110SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.06880821
111E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.06258507
112* CHD1_26751641_Chip-Seq_LNCaP_Human1.02574709
113P68_20966046_ChIP-Seq_HELA_Human1.02400796
114CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.01292865
115RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.00968990
116* GATA6_25053715_ChIP-Seq_YYC3_Human1.00664744
117GATA2_19941826_ChIP-Seq_K562_Human1.00014389
118* SA1_27219007_Chip-Seq_ERYTHROID_Human0.99770803
119GATA2_22383799_ChIP-Seq_G1ME_Mouse0.99510907
120XRN2_22483619_ChIP-Seq_HELA_Human0.98296689
121TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.97576430
122* KDM2B_26808549_Chip-Seq_JURKAT_Human0.97547729
123NFIB_24661679_ChIP-Seq_LUNG_Mouse0.97193547
124HIF1A_21447827_ChIP-Seq_MCF-7_Human0.97170568
125* SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.96815769
126P300_27058665_Chip-Seq_ZR-75-30cells_Human0.96662699
127* BRD4_27068464_Chip-Seq_AML-cells_Mouse0.96558822
128* ATF3_27146783_Chip-Seq_COLON_Human0.95887265
129BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.95360907
130ZFP281_18757296_ChIP-ChIP_E14_Mouse0.93898470
131PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.93866588
132TCF3_18347094_ChIP-ChIP_MESCs_Mouse0.93505541
133SOX2_18555785_ChIP-Seq_MESCs_Mouse0.93434909
134MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.93093024
135* SOX2_18692474_ChIP-Seq_MESCs_Mouse0.91764541
136* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.91721185
137EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.91150691
138CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.90918631
139* DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.90773593
140* FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.89829410
141* MAF_26560356_Chip-Seq_TH2_Human0.89676162
142* KAP1_27257070_Chip-Seq_ESCs_Mouse0.89672843
143* NANOG_18692474_ChIP-Seq_MESCs_Mouse0.88972800
144RACK7_27058665_Chip-Seq_MCF-7_Human0.88464345
145SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.88088650
146* NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.87960553
147PRDM14_21183938_ChIP-Seq_MESCs_Mouse0.87763575
148* RUNX1_27514584_Chip-Seq_MCF-7_Human0.86055157
149ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.86042463

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication3.29166255
2MP0003111_abnormal_nucleus_morphology3.22558174
3MP0010352_gastrointestinal_tract_polyps3.16964853
4MP0005076_abnormal_cell_differentiation3.14910804
5MP0005451_abnormal_body_composition3.03595344
6MP0010094_abnormal_chromosome_stability2.93461786
7MP0003436_decreased_susceptibility_to2.86630512
8MP0008877_abnormal_DNA_methylation2.75032441
9MP0005409_darkened_coat_color2.72343260
10MP0003693_abnormal_embryo_hatching2.71933027
11MP0003077_abnormal_cell_cycle2.67471590
12MP0004957_abnormal_blastocyst_morpholog2.63011668
13MP0002009_preneoplasia2.47564860
14MP0010307_abnormal_tumor_latency2.35728525
15MP0003705_abnormal_hypodermis_morpholog2.33555817
16MP0001730_embryonic_growth_arrest2.30818311
17MP0009278_abnormal_bone_marrow2.21929387
18MP0002653_abnormal_ependyma_morphology2.14182012
19MP0000350_abnormal_cell_proliferation2.06081979
20MP0003172_abnormal_lysosome_physiology2.05773398
21MP0001835_abnormal_antigen_presentation1.95247078
22MP0001672_abnormal_embryogenesis/_devel1.94175627
23MP0005380_embryogenesis_phenotype1.94175627
24MP0002084_abnormal_developmental_patter1.83908280
25MP0004264_abnormal_extraembryonic_tissu1.83847341
26MP0008260_abnormal_autophagy1.83837091
27MP0003984_embryonic_growth_retardation1.83785193
28MP0002088_abnormal_embryonic_growth/wei1.80729448
29MP0004197_abnormal_fetal_growth/weight/1.80257660
30MP0002086_abnormal_extraembryonic_tissu1.80148972
31MP0000685_abnormal_immune_system1.80113688
32MP0001849_ear_inflammation1.77910056
33MP0005387_immune_system_phenotype1.71583370
34MP0001790_abnormal_immune_system1.71583370
35MP0010234_abnormal_vibrissa_follicle1.71475543
36MP0003566_abnormal_cell_adhesion1.69491982
37MP0001697_abnormal_embryo_size1.68247631
38MP0008058_abnormal_DNA_repair1.65249543
39MP0002085_abnormal_embryonic_tissue1.64815513
40MP0004185_abnormal_adipocyte_glucose1.64573949
41MP0003890_abnormal_embryonic-extraembry1.56605427
42MP0004808_abnormal_hematopoietic_stem1.56347790
43MP0001873_stomach_inflammation1.54529776
44MP0008007_abnormal_cellular_replicative1.54231322
45MP0001348_abnormal_lacrimal_gland1.53378660
46MP0005000_abnormal_immune_tolerance1.51707425
47MP0005025_abnormal_response_to1.51060158
48MP0002420_abnormal_adaptive_immunity1.49820500
49MP0002877_abnormal_melanocyte_morpholog1.49250899
50MP0001819_abnormal_immune_cell1.48985139
51MP0002419_abnormal_innate_immunity1.48592432
52MP0002723_abnormal_immune_serum1.47474949
53MP0002452_abnormal_antigen_presenting1.46742305
54MP0002405_respiratory_system_inflammati1.45512690
55MP0002080_prenatal_lethality1.44656108
56MP0000569_abnormal_digit_pigmentation1.38707829
57MP0002396_abnormal_hematopoietic_system1.38677621
58MP0004381_abnormal_hair_follicle1.37448547
59MP0001545_abnormal_hematopoietic_system1.36766503
60MP0005397_hematopoietic_system_phenotyp1.36766503
61MP0003300_gastrointestinal_ulcer1.33191080
62MP0005310_abnormal_salivary_gland1.31034283
63MP0000703_abnormal_thymus_morphology1.30586001
64MP0008961_abnormal_basal_metabolism1.29647629
65MP0001929_abnormal_gametogenesis1.29631135
66MP0004858_abnormal_nervous_system1.27926278
67MP0010155_abnormal_intestine_physiology1.26003445
68MP0000858_altered_metastatic_potential1.25942518
69MP0003828_pulmonary_edema1.23779698
70MP0002210_abnormal_sex_determination1.22677599
71MP0002166_altered_tumor_susceptibility1.21781943
72MP0003763_abnormal_thymus_physiology1.20498068
73MP0003567_abnormal_fetal_cardiomyocyte1.18658476
74MP0003123_paternal_imprinting1.16917238
75MP0003724_increased_susceptibility_to1.13454260
76MP0005058_abnormal_lysosome_morphology1.13134233
77MP0002019_abnormal_tumor_incidence1.11879367
78MP0001851_eye_inflammation1.11516836
79MP0002398_abnormal_bone_marrow1.10894615
80MP0001145_abnormal_male_reproductive1.10832212
81MP0000733_abnormal_muscle_development1.10529018
82MP0005023_abnormal_wound_healing1.10084399
83MP0009703_decreased_birth_body1.09886599
84MP0000490_abnormal_crypts_of1.09179930
85MP0001915_intracranial_hemorrhage1.08972729
86MP0005671_abnormal_response_to1.08356487
87MP0000313_abnormal_cell_death1.06792645
88MP0009672_abnormal_birth_weight1.05774666
89MP0003787_abnormal_imprinting1.05703884
90MP0003121_genomic_imprinting1.05664100
91MP0005410_abnormal_fertilization1.05609048
92MP0003303_peritoneal_inflammation1.05264677
93MP0003119_abnormal_digestive_system1.05170187
94MP0002998_abnormal_bone_remodeling1.04923789
95MP0004947_skin_inflammation1.04704642
96MP0003656_abnormal_erythrocyte_physiolo1.04550263
97MP0002925_abnormal_cardiovascular_devel1.04145409
98MP0000678_abnormal_parathyroid_gland1.03831922
99MP0003183_abnormal_peptide_metabolism1.03251717
100MP0005666_abnormal_adipose_tissue1.03093751
101MP0005464_abnormal_platelet_physiology1.02675102
102MP0009115_abnormal_fat_cell1.02663066
103MP0005621_abnormal_cell_physiology1.00190976
104MP0001293_anophthalmia0.98549007
105MP0001800_abnormal_humoral_immune0.97097726
106MP0005670_abnormal_white_adipose0.97006714
107MP0001533_abnormal_skeleton_physiology0.96375971
108MP0002722_abnormal_immune_system0.95561573
109MP0003786_premature_aging0.95292190
110MP0003453_abnormal_keratinocyte_physiol0.95113589
111MP0003191_abnormal_cellular_cholesterol0.93188650
112MP0003698_abnormal_male_reproductive0.91824725
113MP0002796_impaired_skin_barrier0.90997222
114MP0002006_tumorigenesis0.90116858
115MP0002089_abnormal_postnatal_growth/wei0.89834953
116MP0003866_abnormal_defecation0.88935387
117MP0000653_abnormal_sex_gland0.88415655
118MP0003045_fibrosis0.85744656
119MP0009931_abnormal_skin_appearance0.85432751
120MP0005375_adipose_tissue_phenotype0.85042249
121MP0000689_abnormal_spleen_morphology0.84899101
122MP0010630_abnormal_cardiac_muscle0.84705494
123MP0002138_abnormal_hepatobiliary_system0.83883408
124MP0008932_abnormal_embryonic_tissue0.83745474
125MP0003091_abnormal_cell_migration0.82191470
126MP0005384_cellular_phenotype0.82067749
127MP0002092_abnormal_eye_morphology0.81503748
128MP0003448_altered_tumor_morphology0.79328477
129MP0001784_abnormal_fluid_regulation0.79231921
130MP0005501_abnormal_skin_physiology0.78459241
131MP0002132_abnormal_respiratory_system0.78381843
132MP0003941_abnormal_skin_development0.77861855
133MP0003115_abnormal_respiratory_system0.77857232
134MP0001853_heart_inflammation0.77715324
135MP0009785_altered_susceptibility_to0.76833625
136MP0001845_abnormal_inflammatory_respons0.76730806
137MP0000716_abnormal_immune_system0.76283607
138MP0000266_abnormal_heart_morphology0.76243031
139MP0000428_abnormal_craniofacial_morphol0.76099099
140MP0002697_abnormal_eye_size0.75844256
141MP0009333_abnormal_splenocyte_physiolog0.74949511
142MP0008770_decreased_survivor_rate0.74819028
143MP0004233_abnormal_muscle_weight0.74248014
144MP0000432_abnormal_head_morphology0.73604357
145MP0000003_abnormal_adipose_tissue0.72659632
146MP0002429_abnormal_blood_cell0.72269420

Predicted human phenotypes

RankGene SetZ-score
1Ependymoma (HP:0002888)4.32119628
2Abnormality of the fingertips (HP:0001211)4.03165188
3Abnormality of the astrocytes (HP:0100707)3.27047046
4Astrocytoma (HP:0009592)3.27047046
5Eczematoid dermatitis (HP:0000976)3.23599899
6Volvulus (HP:0002580)3.20861255
7Heterotopia (HP:0002282)3.13121039
8Neoplasm of the oral cavity (HP:0100649)3.05806314
9Obstructive sleep apnea (HP:0002870)3.04098790
10Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.85181835
11Impulsivity (HP:0100710)2.77756733
12Prominent nose (HP:0000448)2.76819240
13Long eyelashes (HP:0000527)2.76596262
14Medulloblastoma (HP:0002885)2.71583030
15Urethral obstruction (HP:0000796)2.69255934
16Anal stenosis (HP:0002025)2.64726672
17Broad face (HP:0000283)2.63785118
18Flat acetabular roof (HP:0003180)2.52988825
19Glioma (HP:0009733)2.52444898
20Proximal placement of thumb (HP:0009623)2.50040707
21Colitis (HP:0002583)2.48825382
22Increased IgE level (HP:0003212)2.48719117
23Deviation of the thumb (HP:0009603)2.47596141
24Ectopic kidney (HP:0000086)2.45094805
25Biliary tract neoplasm (HP:0100574)2.43276712
26Basal cell carcinoma (HP:0002671)2.37305777
27Long palpebral fissure (HP:0000637)2.35443270
28Increased nuchal translucency (HP:0010880)2.35279215
29Selective tooth agenesis (HP:0001592)2.35136622
30Recurrent bacterial skin infections (HP:0005406)2.34860626
31Chromsome breakage (HP:0040012)2.33465715
32Lip pit (HP:0100267)2.32579606
33Malignant gastrointestinal tract tumors (HP:0006749)2.28612693
34Gastrointestinal carcinoma (HP:0002672)2.28612693
35Cellulitis (HP:0100658)2.27595895
36Supernumerary ribs (HP:0005815)2.25732053
37Segmental peripheral demyelination/remyelination (HP:0003481)2.25303382
38Abnormality of the lower motor neuron (HP:0002366)2.24996148
39Neonatal hypoglycemia (HP:0001998)2.24405721
40Dislocated radial head (HP:0003083)2.23133617
41Gastrointestinal infarctions (HP:0005244)2.22632436
42Deep palmar crease (HP:0006191)2.22154168
43Disproportionate tall stature (HP:0001519)2.21422881
44Gastrointestinal inflammation (HP:0004386)2.21329121
45Truncal obesity (HP:0001956)2.19407347
46Shawl scrotum (HP:0000049)2.18234353
47Sandal gap (HP:0001852)2.17134027
48Ankyloglossia (HP:0010296)2.16835821
49Neoplasm of striated muscle (HP:0009728)2.16584958
50Subacute progressive viral hepatitis (HP:0006572)2.16254896
51Abnormality of the distal phalanx of the thumb (HP:0009617)2.16099368
52Chromosomal breakage induced by crosslinking agents (HP:0003221)2.15712004
53Hyperacusis (HP:0010780)2.15653623
54Abnormality of macrophages (HP:0004311)2.15318148
55Viral hepatitis (HP:0006562)2.14554800
56Vertebral arch anomaly (HP:0008438)2.13913543
57Nasal polyposis (HP:0100582)2.12954214
58Recurrent abscess formation (HP:0002722)2.12555387
59Pseudobulbar signs (HP:0002200)2.11548094
60Facial hemangioma (HP:0000329)2.11288269
61Abnormal delayed hypersensitivity skin test (HP:0002963)2.08666163
62Hand muscle atrophy (HP:0009130)2.07184566
63Short humerus (HP:0005792)2.06700748
64Abnormality of the radial head (HP:0003995)2.05985705
65Recurrent fungal infections (HP:0002841)2.04495981
66Cerebral aneurysm (HP:0004944)2.03885637
67Cafe-au-lait spot (HP:0000957)2.03730253
68Sparse lateral eyebrow (HP:0005338)2.02893829
69Abnormality of the labia minora (HP:0012880)2.02437346
70Hereditary nonpolyposis colorectal carcinoma (HP:0006716)2.01833033
71Slow saccadic eye movements (HP:0000514)2.01442998
72Germ cell neoplasia (HP:0100728)1.99605387
73High pitched voice (HP:0001620)1.98464336
74Supernumerary bones of the axial skeleton (HP:0009144)1.98448787
75Persistence of primary teeth (HP:0006335)1.98441776
76Gingivitis (HP:0000230)1.97611182
77Inflammation of the large intestine (HP:0002037)1.96446936
78T lymphocytopenia (HP:0005403)1.96436823
79Macroorchidism (HP:0000053)1.96213628
80Rib fusion (HP:0000902)1.96203237
81Metaphyseal cupping (HP:0003021)1.94695777
82Abnormality of the thoracic spine (HP:0100711)1.92840711
83Hemorrhage of the eye (HP:0011885)1.92797857
84Aplasia/hypoplasia of the humerus (HP:0006507)1.91158483
85Rhabdomyosarcoma (HP:0002859)1.91123926
86Broad palm (HP:0001169)1.91078085
87Vertebral clefting (HP:0008428)1.90713947
88Hypoplastic labia majora (HP:0000059)1.89711342
89Skull defect (HP:0001362)1.89285962
90Ulnar bowing (HP:0003031)1.88709029
91Meningitis (HP:0001287)1.87089730
92Recurrent viral infections (HP:0004429)1.86750907
93Missing ribs (HP:0000921)1.84912790
94Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.83539999
95Short 4th metacarpal (HP:0010044)1.83539999
96Deep venous thrombosis (HP:0002625)1.83487178
97Intestinal fistula (HP:0100819)1.82479135
98Patellar aplasia (HP:0006443)1.81596057
99Acute myeloid leukemia (HP:0004808)1.81030826
100Trigonocephaly (HP:0000243)1.80636613
101Asymmetry of the thorax (HP:0001555)1.80404973
102Amaurosis fugax (HP:0100576)1.80330678
103Cutis marmorata (HP:0000965)1.80262184
104Myositis (HP:0100614)1.80046258
105Chronic mucocutaneous candidiasis (HP:0002728)1.79601501
106Recurrent cutaneous fungal infections (HP:0011370)1.79601501
107Gastrointestinal stroma tumor (HP:0100723)1.78535740
108Low anterior hairline (HP:0000294)1.78305526
109Skin tags (HP:0010609)1.77528680
110Abnormality of oral frenula (HP:0000190)1.76845659
111Vasculitis (HP:0002633)1.75744662
112Abnormality of chromosome stability (HP:0003220)1.75469361
113Distal upper limb amyotrophy (HP:0007149)1.75462842
114Upper limb amyotrophy (HP:0009129)1.75462842
115Abnormality of T cell number (HP:0011839)1.74994649
116Agnosia (HP:0010524)1.74345498
117Spontaneous hematomas (HP:0007420)1.74080481
118Broad thumb (HP:0011304)1.74068781
119Short phalanx of the thumb (HP:0009660)1.74060623
120Spinal muscular atrophy (HP:0007269)1.73059742
121Colon cancer (HP:0003003)1.72580537
122Renal cell carcinoma (HP:0005584)1.71525336
123Abnormality of the nasal mucosa (HP:0000433)1.71482929
124Prolonged bleeding time (HP:0003010)1.71167974
125Male infertility (HP:0003251)1.71033645
126Orchitis (HP:0100796)1.70742618
127Abnormality of the columella (HP:0009929)1.70568991
128Limited elbow extension (HP:0001377)1.70383423
129Thin bony cortex (HP:0002753)1.69411265
130Aneurysm (HP:0002617)1.68594143
131Abnormality of the labia majora (HP:0012881)1.67947797
132Bowel incontinence (HP:0002607)1.67846254
133Autoimmune thrombocytopenia (HP:0001973)1.67505326
134Onion bulb formation (HP:0003383)1.67402828
135Overlapping toe (HP:0001845)1.67105496
136Recurrent bronchitis (HP:0002837)1.66880287
137Dysmetric saccades (HP:0000641)1.66049933
138Recurrent skin infections (HP:0001581)1.65630242
139Polycythemia (HP:0001901)1.65317070
140Abnormality of the salivary glands (HP:0010286)1.65154010
141Narrow palate (HP:0000189)1.64570305
142Absent radius (HP:0003974)1.63857611
143Spinal cord lesions (HP:0100561)1.63427596
144Syringomyelia (HP:0003396)1.63427596
145Osteomyelitis (HP:0002754)1.62788637
146Aplasia/Hypoplasia of the patella (HP:0006498)1.61759881
147Emphysema (HP:0002097)1.61748328
148Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.61373872
149Myelodysplasia (HP:0002863)1.61062705
150Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.60291351
151Short 1st metacarpal (HP:0010034)1.60291351
152Blepharitis (HP:0000498)1.60121909
153Agammaglobulinemia (HP:0004432)1.60066154
154Combined immunodeficiency (HP:0005387)1.59847819
155Oligodactyly (HP:0012165)1.59437243
156Polygenic inheritance (HP:0010982)1.59424034
157Distal lower limb amyotrophy (HP:0008944)1.58860546
158Uterine leiomyosarcoma (HP:0002891)1.58723737
159Leiomyosarcoma (HP:0100243)1.58723737
160Abnormality of the nasal septum (HP:0000419)1.58089199
161Mediastinal lymphadenopathy (HP:0100721)1.57894102
162Seborrheic dermatitis (HP:0001051)1.56945501
163Retrobulbar optic neuritis (HP:0100654)1.56380168
164Optic neuritis (HP:0100653)1.56380168
165Recurrent gram-negative bacterial infections (HP:0005420)1.56327462
166Transitional cell carcinoma of the bladder (HP:0006740)1.55077503
167Obsessive-compulsive behavior (HP:0000722)1.55010966
168Pustule (HP:0200039)1.54329572
169Deep philtrum (HP:0002002)1.54229497
170Abnormality of the aortic arch (HP:0012303)1.53086623
171Abnormality of the peritoneum (HP:0002585)1.52468615
172Fatigue (HP:0012378)1.51685063
173Somatic mutation (HP:0001428)1.51623779

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK126.49175403
2PRPF4B3.67212151
3EEF2K2.93580434
4MAP3K102.84022240
5NEK22.76393403
6BRD42.68371303
7CDC72.62585550
8RIPK42.58670241
9SMG12.31587124
10LATS12.15530299
11ICK2.05305782
12STK101.86829356
13CAMK1D1.74685627
14SIK31.72147844
15EPHA21.69149281
16TTK1.68605650
17MTOR1.67673931
18MAP4K11.64206877
19CAMK1G1.63014696
20PKN21.57405944
21CDK41.57267281
22PNCK1.57028016
23ALK1.51666689
24STK31.46762913
25MAP3K131.45405720
26TRIB31.44426047
27RPS6KB21.42695918
28CHEK11.37104097
29CDK61.35827478
30MAP3K141.35549366
31IRAK41.28685187
32CDK71.28112703
33KSR21.25370044
34WEE11.22987188
35ATR1.19103881
36RIPK11.14167285
37PDK31.13838908
38PDK41.13838908
39PASK1.12513432
40CHEK21.12061186
41STK41.10466036
42PTK61.07529202
43NEK11.01159283
44ATM1.00995395
45TYRO30.99992665
46PIM10.98670881
47ERN10.97066601
48FGFR40.96526917
49IRAK30.96255607
50CDK90.95919784
51TNK20.95488032
52SGK30.95176197
53BLK0.93738550
54TAOK10.93683718
55SIK20.93121788
56MAP3K80.92591657
57PRKD30.92430957
58PLK10.91149306
59HIPK20.91068420
60PDGFRA0.90530182
61* CDK20.89816890
62BTK0.88559706
63MAP3K10.87846264
64AKT30.86950397
65PRKD20.86779762
66GRK60.85449970
67PDGFRB0.84579853
68TTN0.82171696
69FGFR30.82041783
70IKBKE0.81067305
71YES10.79631565
72TSSK60.79419243
73RET0.78935198
74MAP3K30.77623448
75AURKB0.76989059
76STK380.75782243
77MELK0.75173876
78LATS20.74740529
79MAP3K90.74538912
80SCYL20.73428513
81TYK20.71141310
82WNK10.71131635
83JAK30.70195386
84BMX0.69757195
85PDPK10.69576001
86MARK30.69160107
87CSNK1D0.68254386
88CSK0.68113660
89PAK40.67653372
90CHUK0.66697843
91MAPK110.65688490
92SIK10.63765467
93EPHB10.62611324
94MAP3K20.62335284
95RPS6KA20.61614094
96PDK10.61343363
97FLT30.61182387
98CDK10.60762109
99JAK20.59432104
100RPS6KL10.59005630
101RPS6KC10.59005630
102IRAK20.59004532
103MKNK20.58592537
104LRRK20.58545116
105DYRK1B0.56969656
106STK38L0.56816362
107PAK20.55143301
108SGK20.54518181
109DMPK0.54289977
110FES0.54164892
111TAOK30.54095191
112TAOK20.53706311
113CDC42BPA0.53330009
114TBK10.53313251
115JAK10.52849688
116MAPK10.52623214
117FGR0.51776223
118* MAPK140.51745778
119CSF1R0.51426384
120PRKDC0.51365478
121IRAK10.51173022
122CSNK1E0.50647583
123MAPK70.48540376
124PDK20.48291674
125SYK0.47245706
126PTK20.47043173
127RPS6KA60.44988537
128TRPM70.44499899
129* GSK3B0.44461032
130NLK0.44256139
131HCK0.44122351
132ITK0.43625969
133MAP3K60.43434220
134LCK0.43129003
135PRKCI0.42357994
136ZAP700.41826964
137PRKAA10.41433256
138FGFR10.40939892
139MAP2K30.40555551
140MARK20.40181749
141MAPK100.40085036
142SGK4940.39963033
143SGK2230.39963033
144MAP3K70.39551538
145AKT10.37310466
146PLK30.36552691

Predicted pathways (KEGG)

RankGene SetZ-score
1RNA transport_Homo sapiens_hsa030132.53112868
2mRNA surveillance pathway_Homo sapiens_hsa030152.24921988
3Lysine degradation_Homo sapiens_hsa003102.10228158
4Mismatch repair_Homo sapiens_hsa034302.07519666
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.05935825
6Cell cycle_Homo sapiens_hsa041102.01952922
7Spliceosome_Homo sapiens_hsa030401.85454397
8Primary immunodeficiency_Homo sapiens_hsa053401.77952447
9mTOR signaling pathway_Homo sapiens_hsa041501.69454423
10DNA replication_Homo sapiens_hsa030301.63947842
11Antigen processing and presentation_Homo sapiens_hsa046121.61420710
12Notch signaling pathway_Homo sapiens_hsa043301.59387624
13MicroRNAs in cancer_Homo sapiens_hsa052061.53920329
14Adherens junction_Homo sapiens_hsa045201.52535110
15Non-homologous end-joining_Homo sapiens_hsa034501.50527833
16Fanconi anemia pathway_Homo sapiens_hsa034601.48135875
17Leishmaniasis_Homo sapiens_hsa051401.48078042
18Dorso-ventral axis formation_Homo sapiens_hsa043201.48002743
19Chronic myeloid leukemia_Homo sapiens_hsa052201.46129263
20p53 signaling pathway_Homo sapiens_hsa041151.45486595
21Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.43569843
22One carbon pool by folate_Homo sapiens_hsa006701.43293946
23Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.39951000
24ErbB signaling pathway_Homo sapiens_hsa040121.36390646
25Other glycan degradation_Homo sapiens_hsa005111.36008312
26Small cell lung cancer_Homo sapiens_hsa052221.34747427
27Herpes simplex infection_Homo sapiens_hsa051681.34324662
28Toll-like receptor signaling pathway_Homo sapiens_hsa046201.32403699
29Thyroid hormone signaling pathway_Homo sapiens_hsa049191.32088600
30B cell receptor signaling pathway_Homo sapiens_hsa046621.30592874
31Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.29231167
32Base excision repair_Homo sapiens_hsa034101.26812285
33Hepatitis C_Homo sapiens_hsa051601.24503518
34Viral carcinogenesis_Homo sapiens_hsa052031.22302142
35Acute myeloid leukemia_Homo sapiens_hsa052211.21844317
36RNA degradation_Homo sapiens_hsa030181.20647566
37Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.14361542
38Homologous recombination_Homo sapiens_hsa034401.14199815
39HTLV-I infection_Homo sapiens_hsa051661.14157872
40TNF signaling pathway_Homo sapiens_hsa046681.12655048
41T cell receptor signaling pathway_Homo sapiens_hsa046601.11703984
42NF-kappa B signaling pathway_Homo sapiens_hsa040641.06230634
43Transcriptional misregulation in cancer_Homo sapiens_hsa052021.03940789
44Epstein-Barr virus infection_Homo sapiens_hsa051691.03652397
45Prostate cancer_Homo sapiens_hsa052151.03639946
46Phospholipase D signaling pathway_Homo sapiens_hsa040721.02770762
47Colorectal cancer_Homo sapiens_hsa052101.00701967
48Basal transcription factors_Homo sapiens_hsa030221.00673616
49Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.00050893
50Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.99978371
51Non-small cell lung cancer_Homo sapiens_hsa052230.99695222
52Endometrial cancer_Homo sapiens_hsa052130.98553054
53GnRH signaling pathway_Homo sapiens_hsa049120.97832540
54Thyroid cancer_Homo sapiens_hsa052160.96207951
55Nucleotide excision repair_Homo sapiens_hsa034200.95672299
56Tuberculosis_Homo sapiens_hsa051520.94633577
57Hippo signaling pathway_Homo sapiens_hsa043900.94358682
58Insulin resistance_Homo sapiens_hsa049310.93279667
59RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.93068301
60Central carbon metabolism in cancer_Homo sapiens_hsa052300.91784606
61Oocyte meiosis_Homo sapiens_hsa041140.90525241
62Longevity regulating pathway - mammal_Homo sapiens_hsa042110.90300520
63Pancreatic cancer_Homo sapiens_hsa052120.90138020
64Basal cell carcinoma_Homo sapiens_hsa052170.89777601
65Leukocyte transendothelial migration_Homo sapiens_hsa046700.89668178
66Viral myocarditis_Homo sapiens_hsa054160.88741608
67Measles_Homo sapiens_hsa051620.88043297
68Selenocompound metabolism_Homo sapiens_hsa004500.87814710
69Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.87689618
70Influenza A_Homo sapiens_hsa051640.87642029
71Proteoglycans in cancer_Homo sapiens_hsa052050.87386230
72Inositol phosphate metabolism_Homo sapiens_hsa005620.86682774
73Renal cell carcinoma_Homo sapiens_hsa052110.84723567
74Phosphatidylinositol signaling system_Homo sapiens_hsa040700.84474493
75Staphylococcus aureus infection_Homo sapiens_hsa051500.84234418
76FoxO signaling pathway_Homo sapiens_hsa040680.82556958
77Toxoplasmosis_Homo sapiens_hsa051450.80662325
78Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.79997327
79Platelet activation_Homo sapiens_hsa046110.79591427
80Hepatitis B_Homo sapiens_hsa051610.79228814
81HIF-1 signaling pathway_Homo sapiens_hsa040660.77790682
82Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.76502256
83Sphingolipid signaling pathway_Homo sapiens_hsa040710.76436970
84Pathways in cancer_Homo sapiens_hsa052000.76042128
85Type II diabetes mellitus_Homo sapiens_hsa049300.74632395
86Apoptosis_Homo sapiens_hsa042100.74410976
87Adipocytokine signaling pathway_Homo sapiens_hsa049200.74227483
88Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.74156842
89AMPK signaling pathway_Homo sapiens_hsa041520.73771964
90Osteoclast differentiation_Homo sapiens_hsa043800.73346246
91Jak-STAT signaling pathway_Homo sapiens_hsa046300.73135289
92Carbohydrate digestion and absorption_Homo sapiens_hsa049730.72876468
93Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.72715980
94TGF-beta signaling pathway_Homo sapiens_hsa043500.72063187
95Amoebiasis_Homo sapiens_hsa051460.71129402
96VEGF signaling pathway_Homo sapiens_hsa043700.70312183
97Long-term potentiation_Homo sapiens_hsa047200.70249186
98Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.69060955
99Bladder cancer_Homo sapiens_hsa052190.68149107
100Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.67361643
101Glucagon signaling pathway_Homo sapiens_hsa049220.67203000
102Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.67035356
103Neurotrophin signaling pathway_Homo sapiens_hsa047220.66966685
104Regulation of actin cytoskeleton_Homo sapiens_hsa048100.66772739
105Graft-versus-host disease_Homo sapiens_hsa053320.66392000
106MAPK signaling pathway_Homo sapiens_hsa040100.66250848
107Allograft rejection_Homo sapiens_hsa053300.64578503
108NOD-like receptor signaling pathway_Homo sapiens_hsa046210.63894424
109Tight junction_Homo sapiens_hsa045300.63788038
110Malaria_Homo sapiens_hsa051440.62203228
111Autoimmune thyroid disease_Homo sapiens_hsa053200.61257743
112Hematopoietic cell lineage_Homo sapiens_hsa046400.61108276
113Prolactin signaling pathway_Homo sapiens_hsa049170.60595833
114Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.59592180
115Focal adhesion_Homo sapiens_hsa045100.59497887
116Insulin signaling pathway_Homo sapiens_hsa049100.58513082
117Endocytosis_Homo sapiens_hsa041440.57659799
118Estrogen signaling pathway_Homo sapiens_hsa049150.55952420
119AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.54419168
120Glioma_Homo sapiens_hsa052140.54212337
121Shigellosis_Homo sapiens_hsa051310.51914714
122Choline metabolism in cancer_Homo sapiens_hsa052310.51482259
123Rap1 signaling pathway_Homo sapiens_hsa040150.51281597
124Hedgehog signaling pathway_Homo sapiens_hsa043400.51257176
125African trypanosomiasis_Homo sapiens_hsa051430.50332465
126Prion diseases_Homo sapiens_hsa050200.49024720
127Wnt signaling pathway_Homo sapiens_hsa043100.47887886
128Pentose phosphate pathway_Homo sapiens_hsa000300.47690398
129Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.47271166
130Intestinal immune network for IgA production_Homo sapiens_hsa046720.47000881
131Chemokine signaling pathway_Homo sapiens_hsa040620.44039887

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