Rank | Gene Set | Z-score |
---|---|---|
1 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 5.24058278 |
2 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.87830746 |
3 | presynaptic membrane assembly (GO:0097105) | 4.79435079 |
4 | ATP synthesis coupled proton transport (GO:0015986) | 4.74326737 |
5 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.74326737 |
6 | presynaptic membrane organization (GO:0097090) | 4.47926302 |
7 | respiratory electron transport chain (GO:0022904) | 4.30423779 |
8 | behavioral response to nicotine (GO:0035095) | 4.24397007 |
9 | electron transport chain (GO:0022900) | 4.19707497 |
10 | central nervous system myelination (GO:0022010) | 4.18751976 |
11 | axon ensheathment in central nervous system (GO:0032291) | 4.18751976 |
12 | GTP biosynthetic process (GO:0006183) | 4.14789095 |
13 | neuron cell-cell adhesion (GO:0007158) | 4.14660752 |
14 | indolalkylamine metabolic process (GO:0006586) | 3.95563968 |
15 | protein neddylation (GO:0045116) | 3.95431084 |
16 | protein complex biogenesis (GO:0070271) | 3.90563077 |
17 | neural tube formation (GO:0001841) | 3.66556821 |
18 | chaperone-mediated protein transport (GO:0072321) | 3.63222346 |
19 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.58905231 |
20 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.58905231 |
21 | NADH dehydrogenase complex assembly (GO:0010257) | 3.58905231 |
22 | postsynaptic membrane organization (GO:0001941) | 3.53033339 |
23 | epithelial cilium movement (GO:0003351) | 3.47750490 |
24 | cilium movement (GO:0003341) | 3.43132772 |
25 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.42461883 |
26 | pyrimidine nucleobase catabolic process (GO:0006208) | 3.41745764 |
27 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.35669721 |
28 | axonemal dynein complex assembly (GO:0070286) | 3.34766179 |
29 | respiratory chain complex IV assembly (GO:0008535) | 3.23378057 |
30 | long-chain fatty acid biosynthetic process (GO:0042759) | 3.20192635 |
31 | cilium morphogenesis (GO:0060271) | 3.16436729 |
32 | platelet dense granule organization (GO:0060155) | 3.15976647 |
33 | UTP biosynthetic process (GO:0006228) | 3.10627901 |
34 | serotonin metabolic process (GO:0042428) | 3.06680958 |
35 | detection of light stimulus involved in sensory perception (GO:0050962) | 3.05954797 |
36 | detection of light stimulus involved in visual perception (GO:0050908) | 3.05954797 |
37 | fucose catabolic process (GO:0019317) | 3.04456561 |
38 | L-fucose metabolic process (GO:0042354) | 3.04456561 |
39 | L-fucose catabolic process (GO:0042355) | 3.04456561 |
40 | nucleobase catabolic process (GO:0046113) | 3.02465526 |
41 | negative regulation of execution phase of apoptosis (GO:1900118) | 3.01445539 |
42 | indole-containing compound catabolic process (GO:0042436) | 3.01162756 |
43 | indolalkylamine catabolic process (GO:0046218) | 3.01162756 |
44 | tryptophan catabolic process (GO:0006569) | 3.01162756 |
45 | intraciliary transport (GO:0042073) | 3.01009794 |
46 | response to pheromone (GO:0019236) | 3.00438577 |
47 | cytochrome complex assembly (GO:0017004) | 2.99082821 |
48 | cellular ketone body metabolic process (GO:0046950) | 2.98513049 |
49 | primary amino compound metabolic process (GO:1901160) | 2.97154881 |
50 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.94207062 |
51 | hydrogen ion transmembrane transport (GO:1902600) | 2.93904327 |
52 | axoneme assembly (GO:0035082) | 2.93462874 |
53 | neuronal action potential propagation (GO:0019227) | 2.91933580 |
54 | negative regulation of neurotransmitter transport (GO:0051589) | 2.90023410 |
55 | protein K11-linked deubiquitination (GO:0035871) | 2.87925264 |
56 | indole-containing compound metabolic process (GO:0042430) | 2.86378065 |
57 | tryptophan metabolic process (GO:0006568) | 2.85273997 |
58 | nonmotile primary cilium assembly (GO:0035058) | 2.84878589 |
59 | kidney morphogenesis (GO:0060993) | 2.82955036 |
60 | cerebral cortex radially oriented cell migration (GO:0021799) | 2.82404391 |
61 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.81834693 |
62 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 2.81130100 |
63 | mannosylation (GO:0097502) | 2.80478193 |
64 | nucleoside diphosphate phosphorylation (GO:0006165) | 2.80217567 |
65 | alkaloid metabolic process (GO:0009820) | 2.79969679 |
66 | GPI anchor biosynthetic process (GO:0006506) | 2.79770015 |
67 | CTP metabolic process (GO:0046036) | 2.78917767 |
68 | CTP biosynthetic process (GO:0006241) | 2.78917767 |
69 | inositol phosphate catabolic process (GO:0071545) | 2.76852706 |
70 | proton transport (GO:0015992) | 2.76326784 |
71 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 2.75318881 |
72 | protein localization to cilium (GO:0061512) | 2.74579183 |
73 | protein localization to synapse (GO:0035418) | 2.72703374 |
74 | ketone body metabolic process (GO:1902224) | 2.72587706 |
75 | substantia nigra development (GO:0021762) | 2.72039147 |
76 | regulation of cilium movement (GO:0003352) | 2.71272366 |
77 | neuronal action potential (GO:0019228) | 2.69287968 |
78 | hydrogen transport (GO:0006818) | 2.68449374 |
79 | magnesium ion transport (GO:0015693) | 2.68016889 |
80 | regulation of action potential (GO:0098900) | 2.66796796 |
81 | retinal ganglion cell axon guidance (GO:0031290) | 2.66240491 |
82 | positive regulation of synapse assembly (GO:0051965) | 2.65648829 |
83 | establishment of protein localization to Golgi (GO:0072600) | 2.65061308 |
84 | cornea development in camera-type eye (GO:0061303) | 2.64517419 |
85 | regulation of pigment cell differentiation (GO:0050932) | 2.64045657 |
86 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.63885938 |
87 | behavioral response to ethanol (GO:0048149) | 2.62832937 |
88 | protein-cofactor linkage (GO:0018065) | 2.62424615 |
89 | dendritic spine morphogenesis (GO:0060997) | 2.62064231 |
90 | somite development (GO:0061053) | 2.61440560 |
91 | developmental pigmentation (GO:0048066) | 2.61308502 |
92 | neuron recognition (GO:0008038) | 2.59880947 |
93 | photoreceptor cell maintenance (GO:0045494) | 2.58591911 |
94 | signal peptide processing (GO:0006465) | 2.57766559 |
95 | protein polyglutamylation (GO:0018095) | 2.57443239 |
96 | glycosphingolipid biosynthetic process (GO:0006688) | 2.54883642 |
97 | UTP metabolic process (GO:0046051) | 2.54798436 |
98 | reflex (GO:0060004) | 2.54287928 |
99 | positive regulation of oligodendrocyte differentiation (GO:0048714) | 2.54097433 |
100 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.53697651 |
101 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.53147900 |
102 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.52855861 |
103 | termination of RNA polymerase III transcription (GO:0006386) | 2.52855861 |
104 | GPI anchor metabolic process (GO:0006505) | 2.52706160 |
105 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 2.51427078 |
106 | kynurenine metabolic process (GO:0070189) | 2.51154260 |
107 | regulation of catecholamine metabolic process (GO:0042069) | 2.50602765 |
108 | regulation of dopamine metabolic process (GO:0042053) | 2.50602765 |
109 | cullin deneddylation (GO:0010388) | 2.50210232 |
110 | DNA deamination (GO:0045006) | 2.49420544 |
111 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 2.48780956 |
112 | limb bud formation (GO:0060174) | 2.48228795 |
113 | cilium or flagellum-dependent cell motility (GO:0001539) | 2.47286765 |
114 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 2.46659753 |
115 | gamma-aminobutyric acid transport (GO:0015812) | 2.46442760 |
116 | hindbrain development (GO:0030902) | 2.46385231 |
117 | piRNA metabolic process (GO:0034587) | 2.45279539 |
118 | regulation of hexokinase activity (GO:1903299) | 2.44809281 |
119 | regulation of glucokinase activity (GO:0033131) | 2.44809281 |
120 | phosphorylated carbohydrate dephosphorylation (GO:0046838) | 2.43888039 |
121 | inositol phosphate dephosphorylation (GO:0046855) | 2.43888039 |
122 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 2.43697720 |
123 | RNA destabilization (GO:0050779) | 2.43459876 |
124 | positive regulation of protein homodimerization activity (GO:0090073) | 2.43382802 |
125 | keratinocyte development (GO:0003334) | 2.43117688 |
126 | nephron tubule morphogenesis (GO:0072078) | 2.42603657 |
127 | nephron epithelium morphogenesis (GO:0072088) | 2.42603657 |
128 | regulation of mitochondrial translation (GO:0070129) | 2.42305944 |
129 | polyol catabolic process (GO:0046174) | 2.41901438 |
130 | synaptic transmission, cholinergic (GO:0007271) | 2.41794035 |
131 | spinal cord motor neuron differentiation (GO:0021522) | 2.41666465 |
132 | retinal cone cell development (GO:0046549) | 2.41661849 |
133 | prenylation (GO:0097354) | 2.41343849 |
134 | protein prenylation (GO:0018342) | 2.41343849 |
135 | negative regulation of neurotransmitter secretion (GO:0046929) | 2.40401033 |
136 | centriole replication (GO:0007099) | 2.39812013 |
137 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.39393243 |
138 | regulation of neurotransmitter uptake (GO:0051580) | 2.39365635 |
139 | startle response (GO:0001964) | 2.37850317 |
140 | protein targeting to Golgi (GO:0000042) | 2.37563874 |
141 | spermatid nucleus differentiation (GO:0007289) | 2.36259511 |
142 | response to redox state (GO:0051775) | 2.32774741 |
143 | transmission of nerve impulse (GO:0019226) | 2.32724710 |
144 | fatty acid elongation (GO:0030497) | 2.32452362 |
145 | * cilium assembly (GO:0042384) | 2.32204964 |
146 | proteasome assembly (GO:0043248) | 2.31910237 |
147 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.28952813 |
148 | regulation of respiratory system process (GO:0044065) | 2.28516197 |
149 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 2.27454856 |
150 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.26424325 |
151 | 7-methylguanosine RNA capping (GO:0009452) | 2.25555520 |
152 | RNA capping (GO:0036260) | 2.25555520 |
153 | anterograde synaptic vesicle transport (GO:0048490) | 2.25260756 |
154 | * cilium organization (GO:0044782) | 2.24250598 |
155 | neuron fate determination (GO:0048664) | 2.24130273 |
156 | neurotransmitter uptake (GO:0001504) | 2.21950430 |
157 | protein deneddylation (GO:0000338) | 2.20960517 |
158 | regulation of axon regeneration (GO:0048679) | 2.20887703 |
159 | regulation of neuron projection regeneration (GO:0070570) | 2.20887703 |
160 | ATP biosynthetic process (GO:0006754) | 2.20770750 |
161 | phagosome maturation (GO:0090382) | 2.20140722 |
162 | 7-methylguanosine mRNA capping (GO:0006370) | 2.18959158 |
163 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 2.18235041 |
164 | ATP hydrolysis coupled proton transport (GO:0015991) | 2.18235041 |
165 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.18016819 |
166 | C-terminal protein lipidation (GO:0006501) | 2.17798630 |
167 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 2.17684743 |
168 | dopamine biosynthetic process (GO:0042416) | 2.16891878 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.05879107 |
2 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.50806081 |
3 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.95323692 |
4 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.91248493 |
5 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.81894543 |
6 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.66849225 |
7 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.66120723 |
8 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.45067699 |
9 | VDR_22108803_ChIP-Seq_LS180_Human | 2.44011084 |
10 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.34330272 |
11 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.33806585 |
12 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.26931414 |
13 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.24784496 |
14 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 2.17387634 |
15 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.09377676 |
16 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.99422217 |
17 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.99308713 |
18 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.97595911 |
19 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.97579199 |
20 | P300_19829295_ChIP-Seq_ESCs_Human | 1.91497702 |
21 | FUS_26573619_Chip-Seq_HEK293_Human | 1.90472097 |
22 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.89889621 |
23 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.88099061 |
24 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.87951261 |
25 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.84295962 |
26 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.83771262 |
27 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.81606263 |
28 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.79242379 |
29 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.79131403 |
30 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.70218408 |
31 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.63185870 |
32 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.63069685 |
33 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.62976072 |
34 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.60395619 |
35 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.59742968 |
36 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.59717867 |
37 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.58886694 |
38 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.58415558 |
39 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.58130501 |
40 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.56272764 |
41 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.55542249 |
42 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.54392614 |
43 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.53092020 |
44 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.53086212 |
45 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.51625597 |
46 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.51405788 |
47 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.51146005 |
48 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.50917334 |
49 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.50917334 |
50 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.50529726 |
51 | AR_25329375_ChIP-Seq_VCAP_Human | 1.48159010 |
52 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.47349956 |
53 | STAT3_23295773_ChIP-Seq_U87_Human | 1.46439706 |
54 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.46371739 |
55 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.44981373 |
56 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.44899804 |
57 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.43982713 |
58 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.43669557 |
59 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.43661712 |
60 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.43415807 |
61 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.43317012 |
62 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.42429772 |
63 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.42268325 |
64 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.41359875 |
65 | EWS_26573619_Chip-Seq_HEK293_Human | 1.40558478 |
66 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.39327130 |
67 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.38474858 |
68 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.37888194 |
69 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.37445848 |
70 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.37268648 |
71 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.36968042 |
72 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.36968042 |
73 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.36932476 |
74 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.36919326 |
75 | TCF4_23295773_ChIP-Seq_U87_Human | 1.36818010 |
76 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.36439966 |
77 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.35938471 |
78 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 1.35634368 |
79 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.35387527 |
80 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.33354219 |
81 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.32872661 |
82 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.32824042 |
83 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.32146890 |
84 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.32043904 |
85 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.30980062 |
86 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.30803258 |
87 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 1.30587430 |
88 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.29751504 |
89 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.27039376 |
90 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.27039376 |
91 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.26781208 |
92 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.26489478 |
93 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.25650557 |
94 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.25161066 |
95 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.25077259 |
96 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.24938416 |
97 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.24676739 |
98 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.21909343 |
99 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.21756209 |
100 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.21534611 |
101 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.21124003 |
102 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.21124003 |
103 | ZFX_18555785_Chip-Seq_ESCs_Mouse | 1.20905702 |
104 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.18303416 |
105 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.18136734 |
106 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.18090498 |
107 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.17933142 |
108 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.17868134 |
109 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.17727450 |
110 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 1.16803953 |
111 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 1.16418061 |
112 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.16381107 |
113 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.16135303 |
114 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.16058759 |
115 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.14566855 |
116 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.14463661 |
117 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.14463661 |
118 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.14422167 |
119 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.13787912 |
120 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.13736201 |
121 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.12472811 |
122 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.12338864 |
123 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.12293954 |
124 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.11384901 |
125 | PU1_27457419_Chip-Seq_LIVER_Mouse | 1.10193351 |
126 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.10182740 |
127 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.10166734 |
128 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.09058035 |
129 | CTCF_18555785_Chip-Seq_ESCs_Mouse | 1.07281903 |
130 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.05392002 |
131 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.05375760 |
132 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.04283393 |
133 | JUN_21703547_ChIP-Seq_K562_Human | 1.04145791 |
134 | KDM2B_26808549_Chip-Seq_REH_Human | 1.03948920 |
135 | ESRRB_18555785_Chip-Seq_ESCs_Mouse | 1.03641877 |
136 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.03479971 |
137 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.03257944 |
138 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.00528815 |
139 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 0.97950469 |
140 | NCOR_22424771_ChIP-Seq_293T_Human | 0.97939405 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003880_abnormal_central_pattern | 5.40069194 |
2 | MP0000569_abnormal_digit_pigmentation | 3.77527641 |
3 | MP0009379_abnormal_foot_pigmentation | 3.09266989 |
4 | MP0003787_abnormal_imprinting | 2.95145366 |
5 | MP0001188_hyperpigmentation | 2.83160280 |
6 | MP0006276_abnormal_autonomic_nervous | 2.78281777 |
7 | MP0008877_abnormal_DNA_methylation | 2.66968029 |
8 | MP0001529_abnormal_vocalization | 2.65694481 |
9 | MP0001905_abnormal_dopamine_level | 2.42208793 |
10 | MP0003195_calcinosis | 2.38702630 |
11 | MP0006292_abnormal_olfactory_placode | 2.38463214 |
12 | MP0001984_abnormal_olfaction | 2.35849909 |
13 | MP0005423_abnormal_somatic_nervous | 2.29355117 |
14 | MP0005409_darkened_coat_color | 2.27067462 |
15 | MP0003136_yellow_coat_color | 2.14733123 |
16 | MP0004270_analgesia | 2.11069729 |
17 | MP0002734_abnormal_mechanical_nocicepti | 2.07700894 |
18 | MP0002837_dystrophic_cardiac_calcinosis | 2.07330684 |
19 | MP0009745_abnormal_behavioral_response | 2.05516270 |
20 | MP0001968_abnormal_touch/_nociception | 2.00872807 |
21 | MP0000778_abnormal_nervous_system | 1.98204235 |
22 | MP0002272_abnormal_nervous_system | 1.96742097 |
23 | MP0002638_abnormal_pupillary_reflex | 1.96733399 |
24 | MP0001986_abnormal_taste_sensitivity | 1.93736182 |
25 | MP0005645_abnormal_hypothalamus_physiol | 1.92725372 |
26 | MP0002735_abnormal_chemical_nociception | 1.90493840 |
27 | MP0005646_abnormal_pituitary_gland | 1.89199096 |
28 | MP0001486_abnormal_startle_reflex | 1.88472947 |
29 | MP0003635_abnormal_synaptic_transmissio | 1.84689088 |
30 | MP0002064_seizures | 1.83487957 |
31 | MP0002736_abnormal_nociception_after | 1.82534957 |
32 | MP0004742_abnormal_vestibular_system | 1.78863569 |
33 | MP0002572_abnormal_emotion/affect_behav | 1.77837556 |
34 | MP0002102_abnormal_ear_morphology | 1.75626507 |
35 | MP0001485_abnormal_pinna_reflex | 1.72050466 |
36 | MP0003121_genomic_imprinting | 1.69990423 |
37 | MP0000015_abnormal_ear_pigmentation | 1.68245487 |
38 | MP0002063_abnormal_learning/memory/cond | 1.61407075 |
39 | MP0009046_muscle_twitch | 1.61356318 |
40 | MP0003011_delayed_dark_adaptation | 1.60134461 |
41 | MP0005171_absent_coat_pigmentation | 1.58867404 |
42 | MP0004142_abnormal_muscle_tone | 1.57932981 |
43 | MP0002163_abnormal_gland_morphology | 1.57580073 |
44 | MP0010386_abnormal_urinary_bladder | 1.51374985 |
45 | MP0008789_abnormal_olfactory_epithelium | 1.50513426 |
46 | MP0002067_abnormal_sensory_capabilities | 1.50374404 |
47 | MP0000920_abnormal_myelination | 1.49880023 |
48 | MP0005379_endocrine/exocrine_gland_phen | 1.49732683 |
49 | MP0001970_abnormal_pain_threshold | 1.48784800 |
50 | MP0002876_abnormal_thyroid_physiology | 1.47749648 |
51 | MP0004133_heterotaxia | 1.46183012 |
52 | MP0005410_abnormal_fertilization | 1.42465751 |
53 | MP0005551_abnormal_eye_electrophysiolog | 1.42294581 |
54 | MP0006072_abnormal_retinal_apoptosis | 1.36643313 |
55 | MP0000631_abnormal_neuroendocrine_gland | 1.33540111 |
56 | MP0001440_abnormal_grooming_behavior | 1.32335367 |
57 | MP0000372_irregular_coat_pigmentation | 1.32228650 |
58 | MP0002909_abnormal_adrenal_gland | 1.32184334 |
59 | MP0000427_abnormal_hair_cycle | 1.31541441 |
60 | MP0002557_abnormal_social/conspecific_i | 1.31007915 |
61 | MP0004859_abnormal_synaptic_plasticity | 1.29235501 |
62 | MP0004381_abnormal_hair_follicle | 1.27417315 |
63 | MP0001502_abnormal_circadian_rhythm | 1.27262024 |
64 | MP0005394_taste/olfaction_phenotype | 1.27236140 |
65 | MP0005499_abnormal_olfactory_system | 1.27236140 |
66 | MP0002928_abnormal_bile_duct | 1.27147039 |
67 | MP0000026_abnormal_inner_ear | 1.26398556 |
68 | MP0002184_abnormal_innervation | 1.24706092 |
69 | MP0002733_abnormal_thermal_nociception | 1.24272658 |
70 | MP0001963_abnormal_hearing_physiology | 1.22907947 |
71 | MP0008872_abnormal_physiological_respon | 1.21919559 |
72 | MP0005253_abnormal_eye_physiology | 1.17593685 |
73 | MP0002653_abnormal_ependyma_morphology | 1.17155855 |
74 | MP0005174_abnormal_tail_pigmentation | 1.16922061 |
75 | MP0005389_reproductive_system_phenotype | 1.15659374 |
76 | MP0001501_abnormal_sleep_pattern | 1.15657071 |
77 | MP0005386_behavior/neurological_phenoty | 1.14202132 |
78 | MP0004924_abnormal_behavior | 1.14202132 |
79 | MP0002751_abnormal_autonomic_nervous | 1.14000767 |
80 | MP0002277_abnormal_respiratory_mucosa | 1.13254231 |
81 | MP0002938_white_spotting | 1.09413247 |
82 | MP0002160_abnormal_reproductive_system | 1.08942999 |
83 | MP0002882_abnormal_neuron_morphology | 1.07523860 |
84 | MP0008995_early_reproductive_senescence | 1.06277844 |
85 | MP0003938_abnormal_ear_development | 1.06099956 |
86 | MP0008875_abnormal_xenobiotic_pharmacok | 1.05312528 |
87 | MP0008961_abnormal_basal_metabolism | 1.04908640 |
88 | MP0002752_abnormal_somatic_nervous | 1.02940293 |
89 | MP0003890_abnormal_embryonic-extraembry | 1.02894649 |
90 | MP0002234_abnormal_pharynx_morphology | 1.02421651 |
91 | MP0003646_muscle_fatigue | 1.01737379 |
92 | MP0001919_abnormal_reproductive_system | 0.96694921 |
93 | MP0004043_abnormal_pH_regulation | 0.95938847 |
94 | MP0002822_catalepsy | 0.95912769 |
95 | MP0005187_abnormal_penis_morphology | 0.95356048 |
96 | MP0008569_lethality_at_weaning | 0.92409456 |
97 | MP0004147_increased_porphyrin_level | 0.92067560 |
98 | MP0001324_abnormal_eye_pigmentation | 0.92010457 |
99 | MP0002229_neurodegeneration | 0.91820469 |
100 | MP0002066_abnormal_motor_capabilities/c | 0.91634946 |
101 | MP0002095_abnormal_skin_pigmentation | 0.91273808 |
102 | MP0001944_abnormal_pancreas_morphology | 0.87629093 |
103 | MP0000955_abnormal_spinal_cord | 0.87250049 |
104 | MP0004215_abnormal_myocardial_fiber | 0.84735018 |
105 | MP0001664_abnormal_digestion | 0.83817016 |
106 | MP0002148_abnormal_hypersensitivity_rea | 0.83444241 |
107 | MP0005075_abnormal_melanosome_morpholog | 0.83123686 |
108 | MP0000049_abnormal_middle_ear | 0.83108543 |
109 | MP0003634_abnormal_glial_cell | 0.82344933 |
110 | MP0003724_increased_susceptibility_to | 0.80851940 |
111 | MP0000647_abnormal_sebaceous_gland | 0.80806717 |
112 | MP0000566_synostosis | 0.78206474 |
113 | MP0003122_maternal_imprinting | 0.78097469 |
114 | MP0005671_abnormal_response_to | 0.78037033 |
115 | MP0005391_vision/eye_phenotype | 0.76144203 |
116 | MP0001293_anophthalmia | 0.75895738 |
117 | MP0005195_abnormal_posterior_eye | 0.74884039 |
118 | MP0004134_abnormal_chest_morphology | 0.71763190 |
119 | MP0004145_abnormal_muscle_electrophysio | 0.70169726 |
120 | MP0002009_preneoplasia | 0.69950922 |
121 | MP0004885_abnormal_endolymph | 0.69814815 |
122 | MP0003698_abnormal_male_reproductive | 0.69356838 |
123 | MP0002152_abnormal_brain_morphology | 0.67010921 |
124 | MP0002177_abnormal_outer_ear | 0.65054252 |
125 | MP0005408_hypopigmentation | 0.64141161 |
126 | MP0005084_abnormal_gallbladder_morpholo | 0.62866618 |
127 | MP0003183_abnormal_peptide_metabolism | 0.62257750 |
128 | MP0004811_abnormal_neuron_physiology | 0.61361502 |
129 | MP0002132_abnormal_respiratory_system | 0.60452077 |
130 | MP0002693_abnormal_pancreas_physiology | 0.60303159 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Acute necrotizing encephalopathy (HP:0006965) | 4.71897635 |
2 | Mitochondrial inheritance (HP:0001427) | 4.23714492 |
3 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 4.15730670 |
4 | Progressive macrocephaly (HP:0004481) | 4.06686925 |
5 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.03118078 |
6 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.88222404 |
7 | Absent/shortened dynein arms (HP:0200106) | 3.88222404 |
8 | Abnormal ciliary motility (HP:0012262) | 3.68700841 |
9 | Abnormal respiratory motile cilium morphology (HP:0005938) | 3.66284252 |
10 | Abnormal respiratory epithelium morphology (HP:0012253) | 3.66284252 |
11 | Acute encephalopathy (HP:0006846) | 3.65939190 |
12 | Abnormal respiratory motile cilium physiology (HP:0012261) | 3.64064361 |
13 | Increased hepatocellular lipid droplets (HP:0006565) | 3.63994370 |
14 | Renal Fanconi syndrome (HP:0001994) | 3.59306440 |
15 | Hepatocellular necrosis (HP:0001404) | 3.40366877 |
16 | Increased CSF lactate (HP:0002490) | 3.36818425 |
17 | Congenital stationary night blindness (HP:0007642) | 3.32081099 |
18 | Gait imbalance (HP:0002141) | 3.24796885 |
19 | * Medial flaring of the eyebrow (HP:0010747) | 3.19765512 |
20 | Hypothermia (HP:0002045) | 3.16947863 |
21 | Abnormality of the renal medulla (HP:0100957) | 3.11063631 |
22 | Optic disc pallor (HP:0000543) | 3.08804931 |
23 | Congenital primary aphakia (HP:0007707) | 3.05351498 |
24 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 3.04868591 |
25 | Nephrogenic diabetes insipidus (HP:0009806) | 3.03989777 |
26 | Abnormality of the renal cortex (HP:0011035) | 3.01640757 |
27 | Abnormal hair whorl (HP:0010721) | 2.99524977 |
28 | 3-Methylglutaconic aciduria (HP:0003535) | 2.96533535 |
29 | Lipid accumulation in hepatocytes (HP:0006561) | 2.94073676 |
30 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.87696733 |
31 | Retinal dysplasia (HP:0007973) | 2.81724161 |
32 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.79231841 |
33 | Parakeratosis (HP:0001036) | 2.75819616 |
34 | Focal motor seizures (HP:0011153) | 2.75529813 |
35 | Abnormality of renal resorption (HP:0011038) | 2.67453012 |
36 | Type II lissencephaly (HP:0007260) | 2.66298881 |
37 | Rhinitis (HP:0012384) | 2.63777111 |
38 | True hermaphroditism (HP:0010459) | 2.60438751 |
39 | Large for gestational age (HP:0001520) | 2.58964655 |
40 | Exertional dyspnea (HP:0002875) | 2.56527987 |
41 | Chronic hepatic failure (HP:0100626) | 2.53623719 |
42 | Hepatic necrosis (HP:0002605) | 2.50501440 |
43 | Pancreatic fibrosis (HP:0100732) | 2.46146005 |
44 | Intestinal atresia (HP:0011100) | 2.43655017 |
45 | Genital tract atresia (HP:0001827) | 2.43609830 |
46 | Cystic liver disease (HP:0006706) | 2.42089355 |
47 | Gaze-evoked nystagmus (HP:0000640) | 2.41390147 |
48 | Vaginal atresia (HP:0000148) | 2.41259221 |
49 | Leukodystrophy (HP:0002415) | 2.38869193 |
50 | Absent speech (HP:0001344) | 2.33451763 |
51 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.31527668 |
52 | Renal cortical cysts (HP:0000803) | 2.30521946 |
53 | Tubulointerstitial nephritis (HP:0001970) | 2.30291167 |
54 | Polydipsia (HP:0001959) | 2.29702790 |
55 | Abnormal drinking behavior (HP:0030082) | 2.29702790 |
56 | Exercise intolerance (HP:0003546) | 2.28208013 |
57 | Febrile seizures (HP:0002373) | 2.27575615 |
58 | Epileptic encephalopathy (HP:0200134) | 2.27240434 |
59 | Attenuation of retinal blood vessels (HP:0007843) | 2.25348761 |
60 | Atonic seizures (HP:0010819) | 2.22953651 |
61 | Tubular atrophy (HP:0000092) | 2.16998370 |
62 | Hemiparesis (HP:0001269) | 2.16887788 |
63 | Abnormality of midbrain morphology (HP:0002418) | 2.15945842 |
64 | Molar tooth sign on MRI (HP:0002419) | 2.15945842 |
65 | Abnormality of glycolysis (HP:0004366) | 2.15821370 |
66 | Increased serum pyruvate (HP:0003542) | 2.15821370 |
67 | Aplasia/Hypoplasia of the lens (HP:0008063) | 2.15250514 |
68 | Abolished electroretinogram (ERG) (HP:0000550) | 2.12712200 |
69 | Patchy hypopigmentation of hair (HP:0011365) | 2.12421726 |
70 | Pancreatic cysts (HP:0001737) | 2.08725607 |
71 | Bony spicule pigmentary retinopathy (HP:0007737) | 2.08165448 |
72 | Respiratory failure (HP:0002878) | 2.07894127 |
73 | Poor coordination (HP:0002370) | 2.07086603 |
74 | Increased intramyocellular lipid droplets (HP:0012240) | 2.06612604 |
75 | Oligodactyly (hands) (HP:0001180) | 2.06297732 |
76 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.06199198 |
77 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.06199198 |
78 | Increased serum lactate (HP:0002151) | 2.02680421 |
79 | Hyperventilation (HP:0002883) | 2.01820735 |
80 | Widely spaced teeth (HP:0000687) | 1.99810853 |
81 | Respiratory difficulties (HP:0002880) | 1.98558124 |
82 | Lactic acidosis (HP:0003128) | 1.98362330 |
83 | Furrowed tongue (HP:0000221) | 1.98045916 |
84 | Congenital hepatic fibrosis (HP:0002612) | 1.97036830 |
85 | Limb dystonia (HP:0002451) | 1.96896991 |
86 | Broad-based gait (HP:0002136) | 1.95427468 |
87 | Bile duct proliferation (HP:0001408) | 1.95194774 |
88 | Abnormal biliary tract physiology (HP:0012439) | 1.95194774 |
89 | Agitation (HP:0000713) | 1.91634128 |
90 | Dialeptic seizures (HP:0011146) | 1.91455109 |
91 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.90915336 |
92 | Microvesicular hepatic steatosis (HP:0001414) | 1.89278258 |
93 | Inability to walk (HP:0002540) | 1.88676794 |
94 | Congenital, generalized hypertrichosis (HP:0004540) | 1.88041978 |
95 | Methylmalonic aciduria (HP:0012120) | 1.86555909 |
96 | * Postaxial hand polydactyly (HP:0001162) | 1.85688813 |
97 | Nephronophthisis (HP:0000090) | 1.85228815 |
98 | Focal seizures (HP:0007359) | 1.84387310 |
99 | Esotropia (HP:0000565) | 1.84015324 |
100 | Sensory axonal neuropathy (HP:0003390) | 1.83740460 |
101 | White forelock (HP:0002211) | 1.83694095 |
102 | Polyuria (HP:0000103) | 1.82927898 |
103 | Type I transferrin isoform profile (HP:0003642) | 1.81651178 |
104 | Abnormality of vitamin B metabolism (HP:0004340) | 1.80867305 |
105 | Postaxial foot polydactyly (HP:0001830) | 1.80609648 |
106 | Congenital sensorineural hearing impairment (HP:0008527) | 1.80563235 |
107 | Optic nerve hypoplasia (HP:0000609) | 1.80203034 |
108 | Myokymia (HP:0002411) | 1.79908866 |
109 | Narrow forehead (HP:0000341) | 1.79834481 |
110 | Progressive inability to walk (HP:0002505) | 1.79730987 |
111 | Limb hypertonia (HP:0002509) | 1.79155158 |
112 | Protruding tongue (HP:0010808) | 1.78840345 |
113 | Abnormality of the labia minora (HP:0012880) | 1.77475229 |
114 | Chronic bronchitis (HP:0004469) | 1.77407343 |
115 | Genetic anticipation (HP:0003743) | 1.77326752 |
116 | Ketosis (HP:0001946) | 1.77149260 |
117 | Neuroendocrine neoplasm (HP:0100634) | 1.76780299 |
118 | Volvulus (HP:0002580) | 1.75564936 |
119 | Pachygyria (HP:0001302) | 1.74361325 |
120 | X-linked dominant inheritance (HP:0001423) | 1.74302085 |
121 | Renal tubular dysfunction (HP:0000124) | 1.73775976 |
122 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.73540304 |
123 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.73540304 |
124 | Polyphagia (HP:0002591) | 1.73473736 |
125 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.72246041 |
126 | Pendular nystagmus (HP:0012043) | 1.72082296 |
127 | Cerebral edema (HP:0002181) | 1.70539538 |
128 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.70378973 |
129 | Fair hair (HP:0002286) | 1.67920442 |
130 | Nasolacrimal duct obstruction (HP:0000579) | 1.67782943 |
131 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.67128388 |
132 | Glycosuria (HP:0003076) | 1.66754666 |
133 | Preaxial hand polydactyly (HP:0001177) | 1.66517576 |
134 | Sclerocornea (HP:0000647) | 1.63874044 |
135 | Aganglionic megacolon (HP:0002251) | 1.63571353 |
136 | Congenital ichthyosiform erythroderma (HP:0007431) | 1.63458870 |
137 | Male pseudohermaphroditism (HP:0000037) | 1.60840276 |
138 | Abnormality of secondary sexual hair (HP:0009888) | 1.58759337 |
139 | Abnormality of the axillary hair (HP:0100134) | 1.58759337 |
140 | Methylmalonic acidemia (HP:0002912) | 1.56088216 |
141 | Anencephaly (HP:0002323) | 1.55492272 |
142 | Decreased central vision (HP:0007663) | 1.55234573 |
143 | Progressive cerebellar ataxia (HP:0002073) | 1.55140228 |
144 | Septate vagina (HP:0001153) | 1.54994771 |
145 | Asthma (HP:0002099) | 1.53459117 |
146 | Bronchiectasis (HP:0002110) | 1.53358937 |
147 | Pheochromocytoma (HP:0002666) | 1.53286871 |
148 | Lissencephaly (HP:0001339) | 1.53208716 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FRK | 5.55859450 |
2 | CASK | 4.22606247 |
3 | TNIK | 2.89883787 |
4 | STK16 | 2.83345369 |
5 | MAP4K2 | 2.40738097 |
6 | MAP3K12 | 2.26813135 |
7 | MARK1 | 2.12886980 |
8 | PINK1 | 2.09348855 |
9 | ACVR1B | 2.06699112 |
10 | STK39 | 2.03900152 |
11 | MAPK13 | 1.93786803 |
12 | MAP2K7 | 1.91041117 |
13 | OXSR1 | 1.88929757 |
14 | TAOK3 | 1.87358198 |
15 | PBK | 1.86267812 |
16 | CDK19 | 1.82186482 |
17 | IRAK4 | 1.78944017 |
18 | BMPR1B | 1.78684433 |
19 | TXK | 1.77335305 |
20 | BMPR2 | 1.71147248 |
21 | VRK1 | 1.67654096 |
22 | NME1 | 1.61715856 |
23 | GRK7 | 1.58006935 |
24 | MUSK | 1.56551467 |
25 | PRPF4B | 1.56014223 |
26 | ZAK | 1.55391498 |
27 | ADRBK2 | 1.54143090 |
28 | MST4 | 1.53931009 |
29 | INSRR | 1.47756935 |
30 | PAK3 | 1.46282544 |
31 | FGFR2 | 1.45624443 |
32 | TLK1 | 1.40125375 |
33 | BCR | 1.39759880 |
34 | TRIM28 | 1.39689216 |
35 | ARAF | 1.38382309 |
36 | PNCK | 1.38207323 |
37 | DYRK2 | 1.37366622 |
38 | IRAK3 | 1.35747487 |
39 | MKNK2 | 1.35244062 |
40 | IRAK2 | 1.34023491 |
41 | YES1 | 1.32627460 |
42 | PLK2 | 1.28121145 |
43 | NTRK3 | 1.24929980 |
44 | MAPK15 | 1.24304196 |
45 | UHMK1 | 1.22712198 |
46 | EPHA4 | 1.19485295 |
47 | BCKDK | 1.18329770 |
48 | CSNK1G3 | 1.10823597 |
49 | MKNK1 | 1.10639902 |
50 | CAMK2B | 1.10016823 |
51 | GRK5 | 1.07790060 |
52 | WNK4 | 1.07447043 |
53 | LIMK1 | 1.06922361 |
54 | NEK6 | 1.06833181 |
55 | PKN1 | 1.04336968 |
56 | CAMKK2 | 1.03949674 |
57 | MAPKAPK5 | 1.01312346 |
58 | IRAK1 | 1.01293853 |
59 | RIPK4 | 0.97357183 |
60 | BRAF | 0.96981868 |
61 | SRPK1 | 0.95006741 |
62 | EIF2AK1 | 0.89864018 |
63 | CSNK1A1L | 0.86668922 |
64 | CAMK2A | 0.86207753 |
65 | DYRK1A | 0.85937086 |
66 | FES | 0.82310719 |
67 | ERBB3 | 0.82209709 |
68 | TEC | 0.81365259 |
69 | CSNK1G2 | 0.80601997 |
70 | CSNK1G1 | 0.78624008 |
71 | TGFBR1 | 0.76958606 |
72 | NME2 | 0.75883880 |
73 | FGR | 0.75377149 |
74 | PRKCE | 0.75093818 |
75 | CLK1 | 0.74125180 |
76 | SIK3 | 0.73345577 |
77 | SGK223 | 0.73191923 |
78 | SGK494 | 0.73191923 |
79 | PHKG1 | 0.72921457 |
80 | PHKG2 | 0.72921457 |
81 | WNK3 | 0.72058340 |
82 | CDK3 | 0.71035976 |
83 | STK38L | 0.70564462 |
84 | CAMK2D | 0.69807189 |
85 | MINK1 | 0.67344214 |
86 | NTRK2 | 0.65331584 |
87 | NUAK1 | 0.63550845 |
88 | MAP3K14 | 0.63252634 |
89 | MAP2K6 | 0.62812884 |
90 | MYLK | 0.61884115 |
91 | MAP2K4 | 0.60805381 |
92 | CDK5 | 0.60244635 |
93 | ADRBK1 | 0.60176527 |
94 | STK11 | 0.58254091 |
95 | EIF2AK3 | 0.57657643 |
96 | EIF2AK2 | 0.57418295 |
97 | SGK2 | 0.57371969 |
98 | RPS6KA5 | 0.57283162 |
99 | BLK | 0.56913218 |
100 | NLK | 0.55302302 |
101 | GRK1 | 0.54942626 |
102 | PIK3CA | 0.54295771 |
103 | PIM2 | 0.54139803 |
104 | CAMK2G | 0.53495650 |
105 | ERBB2 | 0.52139582 |
106 | PASK | 0.51186265 |
107 | PRKCQ | 0.50562945 |
108 | MAP3K4 | 0.50103421 |
109 | PTK2B | 0.48846291 |
110 | SYK | 0.48358760 |
111 | IKBKB | 0.46903391 |
112 | HIPK2 | 0.46888117 |
113 | CAMK1 | 0.46270741 |
114 | PRKACA | 0.46084301 |
115 | EPHB2 | 0.44900187 |
116 | CCNB1 | 0.44477561 |
117 | CDK14 | 0.43641604 |
118 | AKT3 | 0.43608617 |
119 | PRKG1 | 0.43418596 |
120 | TNK2 | 0.43176350 |
121 | DAPK2 | 0.41919722 |
122 | CHUK | 0.41535406 |
123 | PRKCG | 0.41464378 |
124 | VRK2 | 0.41336868 |
125 | BRSK2 | 0.40535512 |
126 | PRKCH | 0.40373949 |
127 | STK3 | 0.40000627 |
128 | STK24 | 0.38483249 |
129 | CDK18 | 0.38306998 |
130 | ITK | 0.38217572 |
131 | SGK1 | 0.37548403 |
132 | CSNK1A1 | 0.37519054 |
133 | LYN | 0.37388901 |
134 | PLK3 | 0.36021050 |
135 | CSNK1D | 0.35833400 |
136 | DYRK3 | 0.34655512 |
137 | OBSCN | 0.34286365 |
138 | CDK11A | 0.33702006 |
139 | PRKCZ | 0.33577895 |
140 | FGFR1 | 0.32272660 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.67771086 |
2 | Parkinsons disease_Homo sapiens_hsa05012 | 3.79240037 |
3 | Protein export_Homo sapiens_hsa03060 | 3.52306007 |
4 | Alzheimers disease_Homo sapiens_hsa05010 | 3.12971408 |
5 | Huntingtons disease_Homo sapiens_hsa05016 | 2.91880420 |
6 | Ribosome_Homo sapiens_hsa03010 | 2.53750957 |
7 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.23974395 |
8 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.22731992 |
9 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.15874035 |
10 | Nicotine addiction_Homo sapiens_hsa05033 | 2.13728890 |
11 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 2.07733898 |
12 | Proteasome_Homo sapiens_hsa03050 | 1.95446407 |
13 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.94725000 |
14 | RNA polymerase_Homo sapiens_hsa03020 | 1.92159211 |
15 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.89594893 |
16 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.81437879 |
17 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.78404292 |
18 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.72926811 |
19 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.72762634 |
20 | Phototransduction_Homo sapiens_hsa04744 | 1.70797546 |
21 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.69533196 |
22 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.64614570 |
23 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.55769894 |
24 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.55503793 |
25 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.54102395 |
26 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.50235195 |
27 | Taste transduction_Homo sapiens_hsa04742 | 1.44663379 |
28 | Morphine addiction_Homo sapiens_hsa05032 | 1.43347986 |
29 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.43336419 |
30 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.42263250 |
31 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.33558910 |
32 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.33094162 |
33 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.28656515 |
34 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.27566301 |
35 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.27352817 |
36 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.23576953 |
37 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.22306752 |
38 | GABAergic synapse_Homo sapiens_hsa04727 | 1.22246354 |
39 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.18599744 |
40 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.17427114 |
41 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.13305558 |
42 | Circadian entrainment_Homo sapiens_hsa04713 | 1.13049984 |
43 | Allograft rejection_Homo sapiens_hsa05330 | 1.11697200 |
44 | Olfactory transduction_Homo sapiens_hsa04740 | 1.10314893 |
45 | Basal transcription factors_Homo sapiens_hsa03022 | 1.10291778 |
46 | Peroxisome_Homo sapiens_hsa04146 | 1.05881098 |
47 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.01518164 |
48 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.00475675 |
49 | Circadian rhythm_Homo sapiens_hsa04710 | 1.00409114 |
50 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.98854946 |
51 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.97343680 |
52 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.97011685 |
53 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.96768427 |
54 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.95592018 |
55 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.91834565 |
56 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.91749031 |
57 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.91565704 |
58 | Long-term depression_Homo sapiens_hsa04730 | 0.89876168 |
59 | Purine metabolism_Homo sapiens_hsa00230 | 0.87448087 |
60 | Asthma_Homo sapiens_hsa05310 | 0.86899546 |
61 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.86782753 |
62 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.85922966 |
63 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.84114441 |
64 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.83433805 |
65 | Cocaine addiction_Homo sapiens_hsa05030 | 0.82589733 |
66 | Histidine metabolism_Homo sapiens_hsa00340 | 0.81583144 |
67 | Phagosome_Homo sapiens_hsa04145 | 0.81340503 |
68 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.81281997 |
69 | ABC transporters_Homo sapiens_hsa02010 | 0.80550118 |
70 | Axon guidance_Homo sapiens_hsa04360 | 0.78909286 |
71 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.77113354 |
72 | Retinol metabolism_Homo sapiens_hsa00830 | 0.76179550 |
73 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.75833433 |
74 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.75223302 |
75 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.72425788 |
76 | Long-term potentiation_Homo sapiens_hsa04720 | 0.72067749 |
77 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.71529016 |
78 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.69996602 |
79 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.69979131 |
80 | Insulin secretion_Homo sapiens_hsa04911 | 0.68333600 |
81 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.67162335 |
82 | Renin secretion_Homo sapiens_hsa04924 | 0.66715482 |
83 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.66588408 |
84 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.65170306 |
85 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.63856172 |
86 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.62651810 |
87 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.61336063 |
88 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.61090672 |
89 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.59870277 |
90 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.58591575 |
91 | Alcoholism_Homo sapiens_hsa05034 | 0.57394162 |
92 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.57382423 |
93 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.56871964 |
94 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.54151892 |
95 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.53992005 |
96 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.53838904 |
97 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.53274971 |
98 | Salivary secretion_Homo sapiens_hsa04970 | 0.52006587 |
99 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.52003365 |
100 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.51532795 |
101 | Spliceosome_Homo sapiens_hsa03040 | 0.51355302 |
102 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.50998032 |
103 | Homologous recombination_Homo sapiens_hsa03440 | 0.50677765 |
104 | RNA degradation_Homo sapiens_hsa03018 | 0.50425334 |
105 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.49574669 |
106 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.48786942 |
107 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.48070132 |
108 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.45646204 |
109 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.45172506 |
110 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.44231516 |
111 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.43499706 |
112 | Mineral absorption_Homo sapiens_hsa04978 | 0.42248188 |
113 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.42200654 |
114 | Metabolic pathways_Homo sapiens_hsa01100 | 0.41791585 |
115 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.36817831 |
116 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.35410286 |
117 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.34877100 |
118 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.34841758 |
119 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.34661180 |
120 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.34490296 |
121 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.33842775 |
122 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.33708389 |
123 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.32640474 |
124 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.32205299 |
125 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.30401816 |
126 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.30361199 |
127 | Malaria_Homo sapiens_hsa05144 | 0.29936443 |
128 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.29826770 |
129 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.29358354 |
130 | Other glycan degradation_Homo sapiens_hsa00511 | 0.29148476 |
131 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.28680852 |
132 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.27737901 |
133 | Melanogenesis_Homo sapiens_hsa04916 | 0.25469393 |
134 | Sulfur relay system_Homo sapiens_hsa04122 | 0.23727597 |
135 | Pertussis_Homo sapiens_hsa05133 | 0.23664143 |