BBS1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Mutations in this gene have been observed in patients with the major form (type 1) of Bardet-Biedl syndrome. The encoded protein may play a role in eye, limb, cardiac and reproductive system development. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)5.70531048
2synaptic vesicle maturation (GO:0016188)5.49047296
3axonemal dynein complex assembly (GO:0070286)5.43266364
4positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.23823552
5positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.23046943
6epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)5.16709973
7cilium movement (GO:0003341)5.16647509
8epithelial cilium movement (GO:0003351)5.16065622
9locomotory exploration behavior (GO:0035641)4.98376976
10vocalization behavior (GO:0071625)4.88142123
11protein localization to synapse (GO:0035418)4.73551680
12synaptic vesicle exocytosis (GO:0016079)4.65334131
13regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.61115061
14neuron cell-cell adhesion (GO:0007158)4.52294468
15glutamate secretion (GO:0014047)4.47937469
16regulation of synaptic vesicle exocytosis (GO:2000300)4.45766947
17synaptic vesicle docking involved in exocytosis (GO:0016081)4.31403623
18regulation of glutamate receptor signaling pathway (GO:1900449)4.28083066
19ionotropic glutamate receptor signaling pathway (GO:0035235)4.21223115
20exploration behavior (GO:0035640)3.99105043
21regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.96358376
22axoneme assembly (GO:0035082)3.95684450
23regulation of synaptic vesicle transport (GO:1902803)3.95371108
24regulation of long-term neuronal synaptic plasticity (GO:0048169)3.93941983
25regulation of neuronal synaptic plasticity (GO:0048168)3.91156145
26motile cilium assembly (GO:0044458)3.89542288
27neurotransmitter secretion (GO:0007269)3.85143202
28synaptic transmission, glutamatergic (GO:0035249)3.82545994
29dendritic spine morphogenesis (GO:0060997)3.82455326
30layer formation in cerebral cortex (GO:0021819)3.82000563
31regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.76761536
32glutamate receptor signaling pathway (GO:0007215)3.75018321
33neuron-neuron synaptic transmission (GO:0007270)3.62606941
34neuron recognition (GO:0008038)3.61055120
35neuronal action potential propagation (GO:0019227)3.58134441
36regulation of cilium movement (GO:0003352)3.56563761
37intraciliary transport (GO:0042073)3.53196506
38cellular potassium ion homeostasis (GO:0030007)3.52111339
39transmission of nerve impulse (GO:0019226)3.50200897
40regulation of excitatory postsynaptic membrane potential (GO:0060079)3.48816961
41positive regulation of membrane potential (GO:0045838)3.47335246
42positive regulation of neurotransmitter secretion (GO:0001956)3.46880777
43neurotransmitter-gated ion channel clustering (GO:0072578)3.44854559
44gamma-aminobutyric acid transport (GO:0015812)3.41862341
45long-term memory (GO:0007616)3.41569779
46positive regulation of neurotransmitter transport (GO:0051590)3.40450182
47regulation of synapse structural plasticity (GO:0051823)3.40401937
48retinal cone cell development (GO:0046549)3.40113420
49regulation of postsynaptic membrane potential (GO:0060078)3.38387930
50axonal fasciculation (GO:0007413)3.38069487
51synaptic vesicle endocytosis (GO:0048488)3.35065575
52regulation of neurotransmitter secretion (GO:0046928)3.33929740
53startle response (GO:0001964)3.33615266
54neurotransmitter transport (GO:0006836)3.31198508
55pyrimidine nucleobase catabolic process (GO:0006208)3.28145557
56presynaptic membrane assembly (GO:0097105)3.27630751
57left/right pattern formation (GO:0060972)3.27326093
58long-term synaptic potentiation (GO:0060291)3.26048047
59protein localization to cilium (GO:0061512)3.25802786
60cerebellar Purkinje cell differentiation (GO:0021702)3.24892692
61proline transport (GO:0015824)3.17540148
62membrane hyperpolarization (GO:0060081)3.17401813
63membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.17393778
64regulation of rhodopsin mediated signaling pathway (GO:0022400)3.12788563
65gamma-aminobutyric acid signaling pathway (GO:0007214)3.12760970
66postsynaptic membrane organization (GO:0001941)3.12432683
67* cilium organization (GO:0044782)3.11380670
68regulation of synaptic plasticity (GO:0048167)3.10740298
69regulation of vesicle fusion (GO:0031338)3.09727538
70* cilium assembly (GO:0042384)3.09547684
71auditory behavior (GO:0031223)3.07488114
72dendrite morphogenesis (GO:0048813)3.06615066
73nucleobase catabolic process (GO:0046113)3.05063887
74innervation (GO:0060384)3.04260577
75regulation of neurotransmitter transport (GO:0051588)3.03223526
76protein polyglutamylation (GO:0018095)3.03075363
77cell migration in hindbrain (GO:0021535)3.02924019
78rhodopsin mediated signaling pathway (GO:0016056)3.01460530
79calcium ion-dependent exocytosis (GO:0017156)3.01014975
80positive regulation of synaptic transmission, GABAergic (GO:0032230)3.00707492
81central nervous system myelination (GO:0022010)2.99847655
82axon ensheathment in central nervous system (GO:0032291)2.99847655
83regulation of dendritic spine morphogenesis (GO:0061001)2.99567873
84sodium ion export (GO:0071436)2.98292955
85urinary tract smooth muscle contraction (GO:0014848)2.98103736
86regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.96535889
87regulation of synaptic transmission, glutamatergic (GO:0051966)2.96512059
88presynaptic membrane organization (GO:0097090)2.96374302
89response to auditory stimulus (GO:0010996)2.96138712
90positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.95980556
91chemosensory behavior (GO:0007635)2.95943186
92neuromuscular process controlling balance (GO:0050885)2.93306780
93cilium morphogenesis (GO:0060271)2.93296440
94learning (GO:0007612)2.92873854
95vesicle transport along microtubule (GO:0047496)2.90801967
96positive regulation of synapse maturation (GO:0090129)2.90249485
97membrane depolarization (GO:0051899)2.89615009
98membrane depolarization during action potential (GO:0086010)2.88923176
99G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.88129214
100regulation of microtubule-based movement (GO:0060632)2.87868136
101prepulse inhibition (GO:0060134)2.87854594
102regulation of neurotransmitter levels (GO:0001505)2.87708572
103positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.86937908
104response to histamine (GO:0034776)2.86542904
105negative regulation of synaptic transmission, GABAergic (GO:0032229)2.86487489
106L-amino acid import (GO:0043092)2.85843010
107activation of protein kinase A activity (GO:0034199)2.84811778
108synapse assembly (GO:0007416)2.84328095
109behavioral defense response (GO:0002209)2.84161226
110behavioral fear response (GO:0001662)2.84161226
111regulation of voltage-gated calcium channel activity (GO:1901385)2.82184097
112positive regulation of synaptic transmission (GO:0050806)2.78937942
113striatum development (GO:0021756)2.78899295
114regulation of respiratory system process (GO:0044065)2.78779227
115positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.78663188
116neuronal ion channel clustering (GO:0045161)2.76581510
117glycine transport (GO:0015816)2.75660630
118microtubule bundle formation (GO:0001578)2.75531481
119behavioral response to cocaine (GO:0048148)2.75400209
120negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.73312280
121synapse organization (GO:0050808)2.72280330
122cilium or flagellum-dependent cell motility (GO:0001539)2.71138325
123dendritic spine organization (GO:0097061)2.70116337
124sperm motility (GO:0030317)2.63276155
125neuromuscular synaptic transmission (GO:0007274)2.61556133
126calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.57459972
127* cellular component assembly involved in morphogenesis (GO:0010927)2.56955969
128* nonmotile primary cilium assembly (GO:0035058)2.56856410
129ventricular system development (GO:0021591)2.55819844
130behavioral response to nicotine (GO:0035095)2.53779633
131limb development (GO:0060173)2.53199291
132appendage development (GO:0048736)2.53199291
133negative regulation of cytosolic calcium ion concentration (GO:0051481)2.47882558
134neurotransmitter catabolic process (GO:0042135)2.38328177
135smoothened signaling pathway (GO:0007224)2.35788604
136microtubule-based movement (GO:0007018)2.35260494
137short-term memory (GO:0007614)2.32733945
138retinal ganglion cell axon guidance (GO:0031290)2.31995074
139glycosphingolipid biosynthetic process (GO:0006688)2.31194948
140establishment of mitochondrion localization (GO:0051654)2.29828323
141lung epithelium development (GO:0060428)2.26746406
142regulation of respiratory gaseous exchange (GO:0043576)2.25289806
143positive regulation of synapse assembly (GO:0051965)2.25182718
144positive regulation of dendrite development (GO:1900006)2.24014827
145nephron epithelium morphogenesis (GO:0072088)2.20766681
146nephron tubule morphogenesis (GO:0072078)2.20766681
147left/right axis specification (GO:0070986)2.18764050
148mechanosensory behavior (GO:0007638)2.18669006

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.80403892
2GBX2_23144817_ChIP-Seq_PC3_Human3.59616460
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.82886919
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.73293313
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.71259794
6REST_21632747_ChIP-Seq_MESCs_Mouse2.48749561
7EZH2_18974828_ChIP-Seq_MESCs_Mouse2.44265426
8RNF2_18974828_ChIP-Seq_MESCs_Mouse2.44265426
9JARID2_20075857_ChIP-Seq_MESCs_Mouse2.39656409
10SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.36505409
11SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.35511485
12SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.34524389
13EZH2_27304074_Chip-Seq_ESCs_Mouse2.33459248
14DROSHA_22980978_ChIP-Seq_HELA_Human2.30753501
15MTF2_20144788_ChIP-Seq_MESCs_Mouse2.30409708
16SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.18175056
17EED_16625203_ChIP-ChIP_MESCs_Mouse2.15009630
18ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.13953808
19EZH2_27294783_Chip-Seq_ESCs_Mouse2.13903898
20RARB_27405468_Chip-Seq_BRAIN_Mouse2.13562447
21SUZ12_27294783_Chip-Seq_ESCs_Mouse2.12473473
22GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.08326464
23RNF2_27304074_Chip-Seq_ESCs_Mouse2.04897268
24CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.95992016
25REST_18959480_ChIP-ChIP_MESCs_Mouse1.94607178
26CTBP2_25329375_ChIP-Seq_LNCAP_Human1.92037630
27AR_21572438_ChIP-Seq_LNCaP_Human1.86028449
28TAF15_26573619_Chip-Seq_HEK293_Human1.78360441
29SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.73168376
30TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.68423662
31NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.67610438
32CTBP1_25329375_ChIP-Seq_LNCAP_Human1.66630917
33SMAD4_21799915_ChIP-Seq_A2780_Human1.66196074
34CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.63418299
35CBX2_27304074_Chip-Seq_ESCs_Mouse1.58979152
36ZFP57_27257070_Chip-Seq_ESCs_Mouse1.57914785
37GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.56954812
38PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.49366339
39EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.46249376
40IKZF1_21737484_ChIP-ChIP_HCT116_Human1.43770963
41BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.43050978
42RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.40879943
43BMI1_23680149_ChIP-Seq_NPCS_Mouse1.38783734
44SMAD3_21741376_ChIP-Seq_EPCs_Human1.38128377
45SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.38128019
46* STAT3_23295773_ChIP-Seq_U87_Human1.34680597
47P300_19829295_ChIP-Seq_ESCs_Human1.34145657
48RNF2_27304074_Chip-Seq_NSC_Mouse1.31631186
49ZNF274_21170338_ChIP-Seq_K562_Hela1.30443123
50RING1B_27294783_Chip-Seq_ESCs_Mouse1.28790653
51POU3F2_20337985_ChIP-ChIP_501MEL_Human1.27209489
52PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.26155452
53TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.25327707
54SOX2_21211035_ChIP-Seq_LN229_Gbm1.24981990
55AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.24628938
56* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.24452804
57ERG_21242973_ChIP-ChIP_JURKAT_Human1.23573739
58* PIAS1_25552417_ChIP-Seq_VCAP_Human1.22077696
59CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.21831520
60SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.20193980
61MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.20037495
62CDX2_19796622_ChIP-Seq_MESCs_Mouse1.19914583
63AR_19668381_ChIP-Seq_PC3_Human1.18815517
64TCF4_23295773_ChIP-Seq_U87_Human1.18606786
65CTCF_27219007_Chip-Seq_Bcells_Human1.18406400
66AR_25329375_ChIP-Seq_VCAP_Human1.18323352
67OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.18000770
68FUS_26573619_Chip-Seq_HEK293_Human1.16846984
69RING1B_27294783_Chip-Seq_NPCs_Mouse1.16624589
70IGF1R_20145208_ChIP-Seq_DFB_Human1.16365367
71P53_22127205_ChIP-Seq_FIBROBLAST_Human1.15501319
72* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.15349983
73E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.14490271
74MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.14361962
75WT1_25993318_ChIP-Seq_PODOCYTE_Human1.13061537
76YAP1_20516196_ChIP-Seq_MESCs_Mouse1.11734078
77TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.11037646
78POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.11037646
79TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.10032185
80ZNF217_24962896_ChIP-Seq_MCF-7_Human1.09265404
81TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.09033129
82TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07250617
83SMAD_19615063_ChIP-ChIP_OVARY_Human1.05589004
84VDR_22108803_ChIP-Seq_LS180_Human1.04795374
85PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.04785842
86NR3C1_21868756_ChIP-Seq_MCF10A_Human1.04053739
87RUNX2_22187159_ChIP-Seq_PCA_Human1.03721920
88ARNT_22903824_ChIP-Seq_MCF-7_Human1.03574282
89NR3C1_23031785_ChIP-Seq_PC12_Mouse1.03367723
90NANOG_18555785_Chip-Seq_ESCs_Mouse1.02932355
91ER_23166858_ChIP-Seq_MCF-7_Human1.02613132
92CBP_20019798_ChIP-Seq_JUKART_Human1.01004030
93IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.01004030
94PRDM14_20953172_ChIP-Seq_ESCs_Human1.00965319
95RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.00256322
96AHR_22903824_ChIP-Seq_MCF-7_Human0.99676054
97UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.99493429
98TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.98387925
99SMAD3_21741376_ChIP-Seq_ESCs_Human0.98111800
100CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97560652
101KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.96761239
102MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.96320859
103SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.95202458
104TP53_20018659_ChIP-ChIP_R1E_Mouse0.94802419
105SMAD3_21741376_ChIP-Seq_HESCs_Human0.94080971
106BCAT_22108803_ChIP-Seq_LS180_Human0.93442982
107OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.93339431
108GATA1_26923725_Chip-Seq_HPCs_Mouse0.91469372
109KDM2B_26808549_Chip-Seq_K562_Human0.90798692
110* KDM2B_26808549_Chip-Seq_REH_Human0.89551211
111LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.89464763
112* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.89354086
113SMAD4_21741376_ChIP-Seq_HESCs_Human0.89136628
114DNAJC2_21179169_ChIP-ChIP_NT2_Human0.88720919
115EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.87926806
116MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.86778209

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.51779445
2MP0003880_abnormal_central_pattern4.43345474
3MP0003635_abnormal_synaptic_transmissio3.72311725
4MP0004270_analgesia3.33439033
5MP0009745_abnormal_behavioral_response3.10074058
6MP0002063_abnormal_learning/memory/cond3.00446025
7MP0009046_muscle_twitch2.95922445
8MP0005423_abnormal_somatic_nervous2.91284887
9MP0002064_seizures2.86224952
10* MP0005551_abnormal_eye_electrophysiolog2.74741362
11MP0001486_abnormal_startle_reflex2.61083568
12MP0001968_abnormal_touch/_nociception2.57320168
13* MP0002572_abnormal_emotion/affect_behav2.55580871
14MP0002272_abnormal_nervous_system2.36702692
15MP0002734_abnormal_mechanical_nocicepti2.34819076
16MP0002822_catalepsy2.12354404
17MP0000778_abnormal_nervous_system2.07426016
18* MP0001984_abnormal_olfaction2.00286621
19MP0006072_abnormal_retinal_apoptosis1.95427201
20MP0001501_abnormal_sleep_pattern1.92359758
21MP0005646_abnormal_pituitary_gland1.89998256
22MP0009780_abnormal_chondrocyte_physiolo1.86676493
23MP0005253_abnormal_eye_physiology1.85808862
24MP0002067_abnormal_sensory_capabilities1.85469755
25MP0003136_yellow_coat_color1.85456850
26MP0000566_synostosis1.85049867
27MP0002736_abnormal_nociception_after1.83130656
28MP0002184_abnormal_innervation1.82752045
29MP0004133_heterotaxia1.79936622
30* MP0002557_abnormal_social/conspecific_i1.78884605
31MP0002735_abnormal_chemical_nociception1.71623694
32MP0001440_abnormal_grooming_behavior1.70964506
33MP0004885_abnormal_endolymph1.68977333
34* MP0002882_abnormal_neuron_morphology1.66658140
35MP0005645_abnormal_hypothalamus_physiol1.65735098
36MP0002638_abnormal_pupillary_reflex1.64853553
37MP0002733_abnormal_thermal_nociception1.63722505
38MP0005377_hearing/vestibular/ear_phenot1.61431693
39MP0003878_abnormal_ear_physiology1.61431693
40MP0004811_abnormal_neuron_physiology1.58674447
41MP0008569_lethality_at_weaning1.58544905
42MP0001970_abnormal_pain_threshold1.58189459
43MP0000955_abnormal_spinal_cord1.55111590
44MP0001502_abnormal_circadian_rhythm1.54914329
45MP0006276_abnormal_autonomic_nervous1.54066762
46MP0003787_abnormal_imprinting1.47583580
47MP0004924_abnormal_behavior1.44084282
48MP0005386_behavior/neurological_phenoty1.44084282
49MP0002909_abnormal_adrenal_gland1.42109916
50MP0003879_abnormal_hair_cell1.41049333
51MP0000631_abnormal_neuroendocrine_gland1.38283725
52MP0005410_abnormal_fertilization1.37159482
53MP0003122_maternal_imprinting1.34725068
54* MP0002066_abnormal_motor_capabilities/c1.34340604
55MP0002229_neurodegeneration1.31954136
56MP0004858_abnormal_nervous_system1.30008712
57* MP0002752_abnormal_somatic_nervous1.27429346
58MP0003011_delayed_dark_adaptation1.27284212
59* MP0002152_abnormal_brain_morphology1.26926240
60MP0008875_abnormal_xenobiotic_pharmacok1.26459204
61MP0001188_hyperpigmentation1.25213205
62MP0003329_amyloid_beta_deposits1.20746734
63MP0001905_abnormal_dopamine_level1.20600061
64MP0003283_abnormal_digestive_organ1.17376757
65MP0000569_abnormal_digit_pigmentation1.13119493
66* MP0005499_abnormal_olfactory_system1.12600459
67* MP0005394_taste/olfaction_phenotype1.12600459
68MP0003633_abnormal_nervous_system1.10894599
69* MP0005195_abnormal_posterior_eye1.09898691
70MP0001346_abnormal_lacrimal_gland1.09386939
71MP0002249_abnormal_larynx_morphology1.09178995
72MP0002090_abnormal_vision1.09055857
73MP0001529_abnormal_vocalization1.08769098
74MP0002876_abnormal_thyroid_physiology1.07022490
75MP0001963_abnormal_hearing_physiology1.04646361
76MP0002928_abnormal_bile_duct1.03354649
77MP0002234_abnormal_pharynx_morphology1.03250458
78MP0003938_abnormal_ear_development1.03136124
79MP0004742_abnormal_vestibular_system1.01213202
80MP0004142_abnormal_muscle_tone0.98779240
81MP0003634_abnormal_glial_cell0.98035792
82MP0005409_darkened_coat_color0.98006072
83MP0003631_nervous_system_phenotype0.97914603
84MP0005623_abnormal_meninges_morphology0.96606583
85MP0002282_abnormal_trachea_morphology0.95988763
86MP0005248_abnormal_Harderian_gland0.95487840
87MP0006292_abnormal_olfactory_placode0.91515475
88MP0003690_abnormal_glial_cell0.91107791
89MP0000049_abnormal_middle_ear0.90791720
90MP0002102_abnormal_ear_morphology0.90241332
91MP0008877_abnormal_DNA_methylation0.89821371
92MP0001485_abnormal_pinna_reflex0.89679770
93MP0005503_abnormal_tendon_morphology0.87882404
94MP0010030_abnormal_orbit_morphology0.87586444
95MP0000383_abnormal_hair_follicle0.87171642
96* MP0002069_abnormal_eating/drinking_beha0.86738721
97MP0000920_abnormal_myelination0.86130806
98MP0003861_abnormal_nervous_system0.84485825
99MP0001177_atelectasis0.83687607
100MP0004233_abnormal_muscle_weight0.82535730
101* MP0000026_abnormal_inner_ear0.80689240
102MP0003942_abnormal_urinary_system0.78130172
103MP0005391_vision/eye_phenotype0.78001180
104MP0008995_early_reproductive_senescence0.77298465
105MP0010386_abnormal_urinary_bladder0.75153219
106MP0001299_abnormal_eye_distance/0.74791171
107* MP0003698_abnormal_male_reproductive0.74493796
108MP0008961_abnormal_basal_metabolism0.72680081
109MP0004043_abnormal_pH_regulation0.70905229
110MP0003632_abnormal_nervous_system0.70711473
111MP0005187_abnormal_penis_morphology0.70299116
112* MP0004085_abnormal_heartbeat0.69851490
113MP0004145_abnormal_muscle_electrophysio0.67287185
114MP0005171_absent_coat_pigmentation0.64248154
115MP0000751_myopathy0.63088153
116MP0003121_genomic_imprinting0.61960975
117* MP0002653_abnormal_ependyma_morphology0.59874180
118MP0000013_abnormal_adipose_tissue0.59530978
119MP0001943_abnormal_respiration0.56230342
120MP0008874_decreased_physiological_sensi0.55689210

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)5.70965872
2Myokymia (HP:0002411)4.52519754
3Focal seizures (HP:0007359)4.43589765
4Epileptic encephalopathy (HP:0200134)4.12842133
5Congenital stationary night blindness (HP:0007642)4.07329065
6Nephronophthisis (HP:0000090)4.04320383
7True hermaphroditism (HP:0010459)3.92493950
8Visual hallucinations (HP:0002367)3.89025694
9Abnormality of midbrain morphology (HP:0002418)3.87345349
10Molar tooth sign on MRI (HP:0002419)3.87345349
11Febrile seizures (HP:0002373)3.85712933
12Pancreatic fibrosis (HP:0100732)3.78232780
13Progressive cerebellar ataxia (HP:0002073)3.70440968
14Pancreatic cysts (HP:0001737)3.58624798
15Cystic liver disease (HP:0006706)3.48142123
16Central scotoma (HP:0000603)3.42344478
17Atonic seizures (HP:0010819)3.40988869
18Dynein arm defect of respiratory motile cilia (HP:0012255)3.35846791
19Absent/shortened dynein arms (HP:0200106)3.35846791
20Abnormality of macular pigmentation (HP:0008002)3.33792773
21Abnormality of the renal medulla (HP:0100957)3.32770630
22Bony spicule pigmentary retinopathy (HP:0007737)3.31976775
23Occipital encephalocele (HP:0002085)3.24591915
24Absence seizures (HP:0002121)3.14128306
25Broad-based gait (HP:0002136)3.13659003
26Supranuclear gaze palsy (HP:0000605)3.10287505
27Action tremor (HP:0002345)3.03540831
28Abnormal drinking behavior (HP:0030082)3.02661542
29Polydipsia (HP:0001959)3.02661542
30Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.96401861
31Gaze-evoked nystagmus (HP:0000640)2.93423104
32Generalized tonic-clonic seizures (HP:0002069)2.93390478
33Dyschromatopsia (HP:0007641)2.93060863
34Hyperventilation (HP:0002883)2.87133006
35Dialeptic seizures (HP:0011146)2.81705541
36Abnormal respiratory motile cilium physiology (HP:0012261)2.78932467
37Scotoma (HP:0000575)2.76801878
38Neurofibrillary tangles (HP:0002185)2.74612174
39Chronic hepatic failure (HP:0100626)2.71708366
40Abnormal rod and cone electroretinograms (HP:0008323)2.68977016
41Truncal ataxia (HP:0002078)2.68257737
42Absent rod-and cone-mediated responses on ERG (HP:0007688)2.68159823
43Abnormal ciliary motility (HP:0012262)2.66352981
44Dysdiadochokinesis (HP:0002075)2.65740185
45Postaxial foot polydactyly (HP:0001830)2.64658696
46Ankle clonus (HP:0011448)2.60019901
47Depression (HP:0000716)2.56789023
48Tubular atrophy (HP:0000092)2.56636604
49Polyphagia (HP:0002591)2.53655785
50Type II lissencephaly (HP:0007260)2.53621568
51Protruding tongue (HP:0010808)2.52077547
52Cerebral inclusion bodies (HP:0100314)2.50098212
53* Gait imbalance (HP:0002141)2.48806917
54Chronic bronchitis (HP:0004469)2.48409626
55Abnormal respiratory motile cilium morphology (HP:0005938)2.47439249
56Abnormal respiratory epithelium morphology (HP:0012253)2.47439249
57Hemiparesis (HP:0001269)2.46650666
58Decreased central vision (HP:0007663)2.44793211
59Pendular nystagmus (HP:0012043)2.44721256
60Genetic anticipation (HP:0003743)2.42464794
61Congenital hepatic fibrosis (HP:0002612)2.42140258
62Impaired vibration sensation in the lower limbs (HP:0002166)2.39512596
63Infertility (HP:0000789)2.38927509
64Urinary bladder sphincter dysfunction (HP:0002839)2.37295019
65Poor eye contact (HP:0000817)2.36028946
66Polyuria (HP:0000103)2.33252211
67Anxiety (HP:0000739)2.31833298
68Failure to thrive in infancy (HP:0001531)2.31739933
69Impaired smooth pursuit (HP:0007772)2.31096108
70Bronchiectasis (HP:0002110)2.29951299
71Abnormality of ocular smooth pursuit (HP:0000617)2.29329403
72Dysmetria (HP:0001310)2.28672115
73Retinal dysplasia (HP:0007973)2.27947663
74Aplasia/Hypoplasia of the tongue (HP:0010295)2.27320834
75Sclerocornea (HP:0000647)2.26277527
76* Postaxial hand polydactyly (HP:0001162)2.26269220
77Mutism (HP:0002300)2.25870450
78Absent speech (HP:0001344)2.24684930
79Excessive salivation (HP:0003781)2.22423233
80Drooling (HP:0002307)2.22423233
81Abnormality of the corticospinal tract (HP:0002492)2.22011850
82Pigmentary retinal degeneration (HP:0001146)2.21768404
83Chorioretinal atrophy (HP:0000533)2.21699200
84Choroideremia (HP:0001139)2.20260711
85Tubulointerstitial nephritis (HP:0001970)2.18556700
86Male infertility (HP:0003251)2.17714448
87* Poor coordination (HP:0002370)2.15231691
88* Congenital primary aphakia (HP:0007707)2.13699405
89Megalencephaly (HP:0001355)2.13630637
90Bell-shaped thorax (HP:0001591)2.12476327
91Abolished electroretinogram (ERG) (HP:0000550)2.11588766
92Impaired social interactions (HP:0000735)2.11100453
93Abnormal social behavior (HP:0012433)2.11100453
94Turricephaly (HP:0000262)2.10549359
95Male pseudohermaphroditism (HP:0000037)2.10226091
96* Medial flaring of the eyebrow (HP:0010747)2.10095676
97Amblyopia (HP:0000646)2.09086524
98Stage 5 chronic kidney disease (HP:0003774)2.07170770
99Spastic gait (HP:0002064)2.06884326
100Type II diabetes mellitus (HP:0005978)2.06028825
101Rhinitis (HP:0012384)2.05123198
102Insomnia (HP:0100785)2.04863030
103Epileptiform EEG discharges (HP:0011182)2.04663801
104Postural instability (HP:0002172)2.03461284
105Anencephaly (HP:0002323)2.02331074
106Diplopia (HP:0000651)2.00971562
107Abnormality of binocular vision (HP:0011514)2.00971562
108Stereotypic behavior (HP:0000733)2.00327130
109Abnormal eating behavior (HP:0100738)2.00247053
110EEG with generalized epileptiform discharges (HP:0011198)1.99294640
111* Genital tract atresia (HP:0001827)1.97601342
112Intention tremor (HP:0002080)1.96792116
113Abnormal urine output (HP:0012590)1.95448479
114Aplasia involving bones of the extremities (HP:0009825)1.95008799
115Aplasia involving bones of the upper limbs (HP:0009823)1.95008799
116Aplasia of the phalanges of the hand (HP:0009802)1.95008799
117* Vaginal atresia (HP:0000148)1.93537740
118Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.93308830
119Degeneration of the lateral corticospinal tracts (HP:0002314)1.93308830
120Abnormality of the renal cortex (HP:0011035)1.91481746
121Hypsarrhythmia (HP:0002521)1.88041383
122Lower limb muscle weakness (HP:0007340)1.87235611
123Attenuation of retinal blood vessels (HP:0007843)1.87111484
124Urinary urgency (HP:0000012)1.86522035
125Papilledema (HP:0001085)1.86288799
126* Nephrogenic diabetes insipidus (HP:0009806)1.85614847
127Preaxial hand polydactyly (HP:0001177)1.85434750
128Abnormality of the aortic arch (HP:0012303)1.84532178
129Vitreoretinal degeneration (HP:0000655)1.83100647
130Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.82527057
131Sleep apnea (HP:0010535)1.81899495
132Narrow forehead (HP:0000341)1.81385991
133* Aplasia/Hypoplasia of the lens (HP:0008063)1.80479701
134Photophobia (HP:0000613)1.79586214
135Renal salt wasting (HP:0000127)1.79273827
136Scanning speech (HP:0002168)1.78501390
137Bradykinesia (HP:0002067)1.78077925
138* Specific learning disability (HP:0001328)1.77922777
139Atelectasis (HP:0100750)1.77687849
140Blue irides (HP:0000635)1.76783581
141Abnormality of the lower motor neuron (HP:0002366)1.76075036
142Renal dysplasia (HP:0000110)1.75595230
143Tubulointerstitial abnormality (HP:0001969)1.73491575
144Nasal polyposis (HP:0100582)1.73404703
145Hyperaldosteronism (HP:0000859)1.73170540
146Abnormal biliary tract physiology (HP:0012439)1.70772233
147Bile duct proliferation (HP:0001408)1.70772233
148Hypokalemic alkalosis (HP:0001949)1.70108156
149Abnormality of renal excretion (HP:0011036)1.69881933
150* Broad foot (HP:0001769)1.69583519
151Neoplasm of the heart (HP:0100544)1.64957556
152Increased corneal curvature (HP:0100692)1.64785328
153Keratoconus (HP:0000563)1.64785328
154Bronchomalacia (HP:0002780)1.63378602
155Cerebellar dysplasia (HP:0007033)1.62716872
156* Decreased testicular size (HP:0008734)1.61827368
157Congenital malformation of the right heart (HP:0011723)1.57714293
158Double outlet right ventricle (HP:0001719)1.57714293
159* Left ventricular hypertrophy (HP:0001712)1.55245371
160* Prominent nasal bridge (HP:0000426)1.54396530
161* Retinitis pigmentosa (HP:0000510)1.52925574
162Increased circulating renin level (HP:0000848)1.51942233
163Bifid tongue (HP:0010297)1.51503041
164* Short foot (HP:0001773)1.49542119
165Hyperactive renin-angiotensin system (HP:0000841)1.48949536

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK34.21348634
2EPHA44.18629926
3PNCK3.41168904
4MAP3K93.38681862
5MAPK153.18045200
6MARK12.93244254
7MAP3K42.71459038
8PRKD32.44684152
9NTRK22.36405923
10MAP4K22.35145112
11MAP2K42.29667754
12PAK62.19105255
13MINK12.17501480
14MAP2K72.13686581
15FRK1.96509713
16DAPK21.88120935
17TNIK1.81681017
18CASK1.67339433
19CAMK1G1.59706792
20CAMKK11.57645173
21NTRK11.52691443
22SIK21.52256498
23CDK51.47997179
24BMPR1B1.47024556
25TYRO31.43570738
26EPHA31.37463762
27MAPK131.36244783
28STK381.35571513
29KSR21.34327443
30KSR11.33309789
31PLK21.31124673
32PRPF4B1.27267481
33MAP3K121.25572639
34RIPK41.21494759
35GRK51.20537863
36FES1.17692568
37UHMK11.16398902
38BCKDK1.13783281
39SGK4941.13326887
40SGK2231.13326887
41DYRK21.11336767
42LATS11.11181526
43PRKCG1.09424789
44EPHB21.05015080
45NME11.03737397
46TNK21.02585517
47ERBB21.00471266
48DYRK1B0.99572274
49ICK0.98651559
50GRK10.98537155
51OXSR10.98367258
52PAK30.97982765
53MAP3K70.97721706
54PKN10.97086578
55STK390.96857893
56FER0.95221726
57ADRBK20.93910266
58SGK20.93445762
59STK38L0.92657779
60CSNK1G30.92256963
61WNK30.91706924
62CAMK2A0.90961444
63PHKG20.89011410
64PHKG10.89011410
65CSNK1A1L0.85873823
66DAPK10.85107782
67WNK10.85071909
68MAP3K20.84704719
69DYRK1A0.81880170
70CAMK1D0.81494298
71PTK2B0.80927886
72CAMK10.79372364
73MARK20.77158266
74WNK40.75883034
75AKT30.75707671
76SGK10.75334151
77CDK190.75212159
78PRKAA10.75107740
79CDK180.74824683
80PRKCH0.73911126
81CDK150.73819443
82PINK10.72434017
83LATS20.72300018
84CAMK2B0.71934314
85NEK60.71706926
86CDK140.71647924
87SGK30.71480330
88PDK40.69772309
89PDK30.69772309
90STK110.69043575
91BMPR20.63950931
92MAP2K60.63733310
93MAPK120.63417014
94CDK11A0.63035490
95CSNK1G10.62682434
96ERBB30.61225872
97MUSK0.60827833
98FGFR20.60385560
99MAP3K130.60330298
100CAMK2G0.57936530
101RPS6KA40.57878398
102BCR0.57743530
103CAMKK20.56681997
104MAPK100.54488108
105PRKCZ0.54250250
106CSNK1A10.54152110
107CSNK1G20.53657908
108RPS6KA30.53425678
109CAMK40.53355830
110LMTK20.52868905
111RIPK10.52674527
112FLT30.52458435
113PRKCE0.52382273
114CAMK2D0.52351199
115ARAF0.52124253
116IRAK20.51399008
117PRKACA0.49761895
118CDC42BPA0.49333311
119PRKD20.48909397
120MAPKAPK30.48907754
121RET0.47382675
122TAOK10.46442118
123FGR0.46355227
124ADRBK10.44112748
125EIF2AK20.43260425
126RPS6KA20.43149062
127ALK0.40748144
128MAPKAPK50.40580654
129PRKCB0.40250616
130PDK10.38679644
131SIK30.37801429
132FYN0.37661452
133TIE10.37428037
134INSRR0.37221966
135DDR20.36382977
136ROCK10.36171041
137CSNK1D0.36018479

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047443.93594978
2Nicotine addiction_Homo sapiens_hsa050333.59185954
3Synaptic vesicle cycle_Homo sapiens_hsa047213.08351055
4Olfactory transduction_Homo sapiens_hsa047402.84601483
5GABAergic synapse_Homo sapiens_hsa047272.67802436
6Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.62412600
7Circadian entrainment_Homo sapiens_hsa047132.57428080
8Glutamatergic synapse_Homo sapiens_hsa047242.50109607
9Morphine addiction_Homo sapiens_hsa050322.44242013
10Long-term potentiation_Homo sapiens_hsa047202.41833472
11Amphetamine addiction_Homo sapiens_hsa050312.31440251
12Dopaminergic synapse_Homo sapiens_hsa047282.14795504
13Insulin secretion_Homo sapiens_hsa049112.07047003
14Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.99625283
15Salivary secretion_Homo sapiens_hsa049701.96513701
16Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.94591191
17Taste transduction_Homo sapiens_hsa047421.91363709
18Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.87116019
19Cholinergic synapse_Homo sapiens_hsa047251.84018556
20Gastric acid secretion_Homo sapiens_hsa049711.78143032
21Serotonergic synapse_Homo sapiens_hsa047261.67810508
22Cocaine addiction_Homo sapiens_hsa050301.65902679
23Aldosterone synthesis and secretion_Homo sapiens_hsa049251.62486347
24Renin secretion_Homo sapiens_hsa049241.60220840
25Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.58970780
26Long-term depression_Homo sapiens_hsa047301.53793417
27Butanoate metabolism_Homo sapiens_hsa006501.53629238
28Oxytocin signaling pathway_Homo sapiens_hsa049211.49372679
29Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.49014453
30Calcium signaling pathway_Homo sapiens_hsa040201.44656543
31Linoleic acid metabolism_Homo sapiens_hsa005911.41653894
32Axon guidance_Homo sapiens_hsa043601.33531975
33Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.33264209
34GnRH signaling pathway_Homo sapiens_hsa049121.32713430
35alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.32636932
36Collecting duct acid secretion_Homo sapiens_hsa049661.30853401
37cAMP signaling pathway_Homo sapiens_hsa040241.28473964
38Type II diabetes mellitus_Homo sapiens_hsa049301.26729551
39beta-Alanine metabolism_Homo sapiens_hsa004101.18408101
40Histidine metabolism_Homo sapiens_hsa003401.16469667
41Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.15947729
42Gap junction_Homo sapiens_hsa045401.13913648
43Fatty acid biosynthesis_Homo sapiens_hsa000611.13150734
44Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.11233175
45Phosphatidylinositol signaling system_Homo sapiens_hsa040701.10732412
46Ether lipid metabolism_Homo sapiens_hsa005651.10707728
47Glioma_Homo sapiens_hsa052141.09513895
48ErbB signaling pathway_Homo sapiens_hsa040121.08390433
49Estrogen signaling pathway_Homo sapiens_hsa049151.08170237
50Steroid biosynthesis_Homo sapiens_hsa001001.07989445
51Propanoate metabolism_Homo sapiens_hsa006401.07599153
52Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.07338098
53Melanogenesis_Homo sapiens_hsa049161.06919145
54cGMP-PKG signaling pathway_Homo sapiens_hsa040221.06270026
55ABC transporters_Homo sapiens_hsa020101.02077140
56Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.99435257
57Dorso-ventral axis formation_Homo sapiens_hsa043200.98073092
58Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.97896416
59Maturity onset diabetes of the young_Homo sapiens_hsa049500.96265549
60Chemical carcinogenesis_Homo sapiens_hsa052040.94955193
61Phenylalanine metabolism_Homo sapiens_hsa003600.94091962
62Fatty acid metabolism_Homo sapiens_hsa012120.91577115
63Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.91413639
64Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.89971735
65Oocyte meiosis_Homo sapiens_hsa041140.86392995
66Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.85469162
67Vascular smooth muscle contraction_Homo sapiens_hsa042700.84766151
68Cardiac muscle contraction_Homo sapiens_hsa042600.84679063
69Vibrio cholerae infection_Homo sapiens_hsa051100.83407988
70Pancreatic secretion_Homo sapiens_hsa049720.82912389
71Carbohydrate digestion and absorption_Homo sapiens_hsa049730.80788008
72Arginine and proline metabolism_Homo sapiens_hsa003300.79729737
73Notch signaling pathway_Homo sapiens_hsa043300.79693065
74Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.79628218
75Thyroid hormone synthesis_Homo sapiens_hsa049180.78861866
76Primary bile acid biosynthesis_Homo sapiens_hsa001200.78313098
77Peroxisome_Homo sapiens_hsa041460.76747463
78Glycerophospholipid metabolism_Homo sapiens_hsa005640.75969619
79Dilated cardiomyopathy_Homo sapiens_hsa054140.74544544
80Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.73905156
81Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.73279436
82MAPK signaling pathway_Homo sapiens_hsa040100.72795687
83Phospholipase D signaling pathway_Homo sapiens_hsa040720.72759331
84Regulation of autophagy_Homo sapiens_hsa041400.72207670
85Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.71470988
86Tyrosine metabolism_Homo sapiens_hsa003500.70010604
87Huntingtons disease_Homo sapiens_hsa050160.69789230
88Circadian rhythm_Homo sapiens_hsa047100.68576147
89Lysine degradation_Homo sapiens_hsa003100.66365689
90Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.65395724
91Alcoholism_Homo sapiens_hsa050340.64544493
92Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.63388467
93Ras signaling pathway_Homo sapiens_hsa040140.63386582
94Choline metabolism in cancer_Homo sapiens_hsa052310.63047491
95Vitamin B6 metabolism_Homo sapiens_hsa007500.61951166
96Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.61769266
97Steroid hormone biosynthesis_Homo sapiens_hsa001400.61749282
98Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.61064775
99Tight junction_Homo sapiens_hsa045300.60312764
100Wnt signaling pathway_Homo sapiens_hsa043100.59695789
101Thyroid hormone signaling pathway_Homo sapiens_hsa049190.59049929
102Nitrogen metabolism_Homo sapiens_hsa009100.56818524
103Glucagon signaling pathway_Homo sapiens_hsa049220.56795665
104Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.55119688
105Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.54928592
106Rap1 signaling pathway_Homo sapiens_hsa040150.53951090
107Oxidative phosphorylation_Homo sapiens_hsa001900.53921539
108Neurotrophin signaling pathway_Homo sapiens_hsa047220.52795901
109VEGF signaling pathway_Homo sapiens_hsa043700.52707660
110Inositol phosphate metabolism_Homo sapiens_hsa005620.51227403
111Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.50002650
112Fatty acid degradation_Homo sapiens_hsa000710.49980750
113Retinol metabolism_Homo sapiens_hsa008300.49559604
114AMPK signaling pathway_Homo sapiens_hsa041520.49199393
115Type I diabetes mellitus_Homo sapiens_hsa049400.48624534
116Arachidonic acid metabolism_Homo sapiens_hsa005900.48258328
117Sphingolipid signaling pathway_Homo sapiens_hsa040710.47968453
118Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.47736315
119Protein digestion and absorption_Homo sapiens_hsa049740.47149019
120Endometrial cancer_Homo sapiens_hsa052130.46813162
121Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.46514478
122Renal cell carcinoma_Homo sapiens_hsa052110.45967842
123Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.44723915
124Hedgehog signaling pathway_Homo sapiens_hsa043400.44177166
125Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.42557374
126Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.41403092
127Prion diseases_Homo sapiens_hsa050200.41182287
128Non-small cell lung cancer_Homo sapiens_hsa052230.39106056
129Ovarian steroidogenesis_Homo sapiens_hsa049130.37818003
130Longevity regulating pathway - mammal_Homo sapiens_hsa042110.37006155
131Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.36436673
132Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.35269759
133Endocytosis_Homo sapiens_hsa041440.34764387
134mTOR signaling pathway_Homo sapiens_hsa041500.34180505
135Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.33173707
136Bile secretion_Homo sapiens_hsa049760.32993319
137Insulin signaling pathway_Homo sapiens_hsa049100.31142826
138SNARE interactions in vesicular transport_Homo sapiens_hsa041300.29768355
139Basal cell carcinoma_Homo sapiens_hsa052170.26804858
140Chemokine signaling pathway_Homo sapiens_hsa040620.26379683
141Mineral absorption_Homo sapiens_hsa049780.25084665
142Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.22857099
143Hippo signaling pathway_Homo sapiens_hsa043900.22117741

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