BBX

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)4.36761535
2mitotic sister chromatid cohesion (GO:0007064)4.12538065
3nuclear pore organization (GO:0006999)3.98463006
4centriole replication (GO:0007099)3.59931802
5pore complex assembly (GO:0046931)3.39255754
6antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.35917328
7establishment of protein localization to Golgi (GO:0072600)3.31148056
8genitalia morphogenesis (GO:0035112)3.26321783
9radial glial cell differentiation (GO:0060019)3.21451982
10regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.18851477
11regulation of protein polyubiquitination (GO:1902914)3.14586511
12protein targeting to Golgi (GO:0000042)3.14510164
13cerebral cortex radially oriented cell migration (GO:0021799)3.04823230
14nonmotile primary cilium assembly (GO:0035058)3.00725305
15retrograde transport, vesicle recycling within Golgi (GO:0000301)3.00711479
16fusion of sperm to egg plasma membrane (GO:0007342)2.97864203
17negative regulation of DNA repair (GO:0045738)2.94150321
18establishment of nucleus localization (GO:0040023)2.90327029
19nucleus localization (GO:0051647)2.88647135
20cytoplasmic mRNA processing body assembly (GO:0033962)2.86911581
21positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)2.84943793
22regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)2.84943793
23resolution of meiotic recombination intermediates (GO:0000712)2.84603966
24regulation of RNA export from nucleus (GO:0046831)2.81841378
25negative regulation of potassium ion transmembrane transporter activity (GO:1901017)2.80316197
26regulation of transforming growth factor beta2 production (GO:0032909)2.77808796
27tongue development (GO:0043586)2.75828509
28definitive hemopoiesis (GO:0060216)2.73986923
29regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)2.73625265
30positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO2.73625265
31COPI coating of Golgi vesicle (GO:0048205)2.70597360
32Golgi transport vesicle coating (GO:0048200)2.70597360
33regulation of DNA endoreduplication (GO:0032875)2.69634234
34regulation of centriole replication (GO:0046599)2.63732772
35pre-miRNA processing (GO:0031054)2.62707351
36centriole assembly (GO:0098534)2.62121707
37regulation of mRNA catabolic process (GO:0061013)2.61962372
38cilium or flagellum-dependent cell motility (GO:0001539)2.60582787
39piRNA metabolic process (GO:0034587)2.58511050
40protein localization to Golgi apparatus (GO:0034067)2.57913105
41cilium assembly (GO:0042384)2.56110289
42embryonic foregut morphogenesis (GO:0048617)2.56030235
43paraxial mesoderm development (GO:0048339)2.55400900
44regulation of sarcomere organization (GO:0060297)2.54675416
45epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.53481503
46epithelial cilium movement (GO:0003351)2.53279565
47positive regulation of mRNA catabolic process (GO:0061014)2.52892210
48ER overload response (GO:0006983)2.52805954
49intraciliary transport (GO:0042073)2.52439619
50cilium morphogenesis (GO:0060271)2.51244251
51acrosome assembly (GO:0001675)2.49937108
52anterior/posterior axis specification, embryo (GO:0008595)2.49796878
53cellular response to vitamin D (GO:0071305)2.49195319
54cilium organization (GO:0044782)2.49091616
55substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.48892887
56substrate-independent telencephalic tangential migration (GO:0021826)2.48892887
57regulation of male gonad development (GO:2000018)2.47691208
58negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.46453929
59negative regulation of translation, ncRNA-mediated (GO:0040033)2.46453929
60regulation of translation, ncRNA-mediated (GO:0045974)2.46453929
61retinal ganglion cell axon guidance (GO:0031290)2.45166007
62reciprocal meiotic recombination (GO:0007131)2.44591365
63reciprocal DNA recombination (GO:0035825)2.44591365
64histone H3-K36 demethylation (GO:0070544)2.43221619
65cellular response to interferon-alpha (GO:0035457)2.42657863
66regulation of histone H3-K9 methylation (GO:0051570)2.41337163
67limb development (GO:0060173)2.41244382
68appendage development (GO:0048736)2.41244382
69replicative senescence (GO:0090399)2.40278255
70photoreceptor cell differentiation (GO:0046530)2.39486124
71eye photoreceptor cell differentiation (GO:0001754)2.39486124
72monoubiquitinated protein deubiquitination (GO:0035520)2.39137160
73pericardium development (GO:0060039)2.38948869
74otic vesicle formation (GO:0030916)2.38770532
75prenylation (GO:0097354)2.38240001
76protein prenylation (GO:0018342)2.38240001
77nephron tubule morphogenesis (GO:0072078)2.38113667
78nephron epithelium morphogenesis (GO:0072088)2.38113667
79embryonic camera-type eye morphogenesis (GO:0048596)2.34107172
80Sertoli cell development (GO:0060009)2.33705306
81Golgi to endosome transport (GO:0006895)2.32855405
82embryonic body morphogenesis (GO:0010172)2.31851489
83negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147)2.30981927
84seminiferous tubule development (GO:0072520)2.30536576
85auditory receptor cell differentiation (GO:0042491)2.30409093
86metanephric mesenchyme development (GO:0072075)2.30166007
87histone H3-K9 methylation (GO:0051567)2.30136760
88microtubule anchoring (GO:0034453)2.29077172
89regulation of secondary heart field cardioblast proliferation (GO:0003266)2.28694355
90regulation of cardioblast proliferation (GO:0003264)2.28694355
91negative regulation of fibroblast growth factor receptor signaling pathway (GO:0040037)2.28603303
92DNA-dependent DNA replication (GO:0006261)2.28585375
93dorsal/ventral axis specification (GO:0009950)2.27475942
94phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.27126319
95interkinetic nuclear migration (GO:0022027)2.26887130
96negative regulation of keratinocyte proliferation (GO:0010839)2.26814397
97positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc2.26369565
98hepatocyte apoptotic process (GO:0097284)2.26032735
99histone mRNA catabolic process (GO:0071044)2.25776914
100regulation of fibroblast apoptotic process (GO:2000269)2.25531580
101left/right axis specification (GO:0070986)2.24782219
102pituitary gland development (GO:0021983)2.24716219
103replication fork processing (GO:0031297)2.24614791
104exocrine pancreas development (GO:0031017)2.24241006
105lens development in camera-type eye (GO:0002088)2.23900117
106positive regulation of histone H3-K4 methylation (GO:0051571)2.23345799
107sequestering of metal ion (GO:0051238)2.23063675
108positive regulation of SMAD protein import into nucleus (GO:0060391)2.22740195
109smoothened signaling pathway (GO:0007224)2.22402331
110positive regulation of male gonad development (GO:2000020)2.22370256
111sister chromatid cohesion (GO:0007062)2.21052438
112positive regulation of mRNA 3-end processing (GO:0031442)2.21004492
113meiotic chromosome segregation (GO:0045132)2.20262397
114negative regulation of organ growth (GO:0046621)2.19951702
115smooth muscle tissue development (GO:0048745)2.19429859
116cell morphogenesis involved in neuron differentiation (GO:0048667)2.19268371
117regulation of nucleobase-containing compound transport (GO:0032239)2.19206396
118negative regulation of JUN kinase activity (GO:0043508)2.18871031
119single strand break repair (GO:0000012)2.18457886
120regulation of cell proliferation involved in heart morphogenesis (GO:2000136)2.17993710
121negative regulation of cytosolic calcium ion concentration (GO:0051481)2.16196095
122negative regulation of potassium ion transmembrane transport (GO:1901380)2.16164720
123mesenchymal cell differentiation (GO:0048762)2.15813876
124multicellular organism reproduction (GO:0032504)2.15285873
125sperm motility (GO:0030317)2.15042539
126response to interferon-alpha (GO:0035455)2.14840211
127synapsis (GO:0007129)2.14708737
128cellular component assembly involved in morphogenesis (GO:0010927)2.14577303
129notochord development (GO:0030903)2.14424997
130kidney mesenchyme development (GO:0072074)2.14382700
131positive regulation of cardiac muscle cell differentiation (GO:2000727)2.14260834
132embryonic pattern specification (GO:0009880)2.14221785
133kidney morphogenesis (GO:0060993)2.13272304
134hippo signaling (GO:0035329)2.12190794
135regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.11572518
136CENP-A containing nucleosome assembly (GO:0034080)2.10841209
137renal tubule morphogenesis (GO:0061333)2.10726342
138kinetochore organization (GO:0051383)2.10686929
139negative regulation of smooth muscle cell differentiation (GO:0051151)2.10666788
140oocyte development (GO:0048599)2.10609242
141somite rostral/caudal axis specification (GO:0032525)2.10489091
142cell wall macromolecule catabolic process (GO:0016998)2.10204749
143cell wall macromolecule metabolic process (GO:0044036)2.10204749
144presynaptic membrane assembly (GO:0097105)2.10168999
145cell-cell signaling involved in cell fate commitment (GO:0045168)2.09694879
146lateral sprouting from an epithelium (GO:0060601)2.09600081
147regulation of establishment of cell polarity (GO:2000114)2.09527119
148regulation of posttranscriptional gene silencing (GO:0060147)2.09457331
149regulation of gene silencing by miRNA (GO:0060964)2.09457331
150regulation of gene silencing by RNA (GO:0060966)2.09457331
151neural tube formation (GO:0001841)2.08778414
152ribonucleoprotein complex disassembly (GO:0032988)2.08630260
153embryonic axis specification (GO:0000578)2.08533637
154positive regulation of extrinsic apoptotic signaling pathway via death domain receptors (GO:1902043)2.07827628
155positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.06509563
156positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.06509563
157positive regulation of mitotic sister chromatid separation (GO:1901970)2.06509563
158interleukin-6-mediated signaling pathway (GO:0070102)2.05811365
159regulation of SMAD protein import into nucleus (GO:0060390)2.05574034
160response to lipoprotein particle (GO:0055094)2.05469974
161negative regulation of fibroblast apoptotic process (GO:2000270)2.04454310
162male meiosis (GO:0007140)2.04196638
163response to X-ray (GO:0010165)2.03508913
164sperm-egg recognition (GO:0035036)2.02959375
165positive regulation of hormone biosynthetic process (GO:0046886)2.02467976
166snRNA processing (GO:0016180)2.02362045
167regulation of heart morphogenesis (GO:2000826)2.02288268
168cellular response to vitamin (GO:0071295)2.01491153
169axonemal dynein complex assembly (GO:0070286)2.01468847
170T-helper 1 type immune response (GO:0042088)2.01422190
171histone H3-K9 modification (GO:0061647)2.01409019
172type B pancreatic cell development (GO:0003323)2.00835937
173signal peptide processing (GO:0006465)1.99764827
174regulation of non-canonical Wnt signaling pathway (GO:2000050)1.99453694
175regulation of stem cell maintenance (GO:2000036)1.98899084
176embryonic retina morphogenesis in camera-type eye (GO:0060059)1.98746295
177spermatid development (GO:0007286)1.98432054
178regulation of branching involved in salivary gland morphogenesis (GO:0060693)1.98092698
179peptidyl-lysine trimethylation (GO:0018023)1.97756610
180negative regulation of B cell proliferation (GO:0030889)1.97064217
181myelin assembly (GO:0032288)1.96233231

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse5.26594407
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.62537730
3HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.61617603
4SALL1_21062744_ChIP-ChIP_HESCs_Human3.31176815
5IRF8_22096565_ChIP-ChIP_GC-B_Human3.08586898
6E2F7_22180533_ChIP-Seq_HELA_Human3.05969550
7EGR1_19374776_ChIP-ChIP_THP-1_Human2.96317612
8GBX2_23144817_ChIP-Seq_PC3_Human2.84785035
9* CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.84295395
10RBPJ_22232070_ChIP-Seq_NCS_Mouse2.68277923
11TAF15_26573619_Chip-Seq_HEK293_Human2.58671220
12BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.54566117
13KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.35393907
14ZFP57_27257070_Chip-Seq_ESCs_Mouse2.33081201
15IGF1R_20145208_ChIP-Seq_DFB_Human2.25432382
16P300_19829295_ChIP-Seq_ESCs_Human2.11035397
17TP63_19390658_ChIP-ChIP_HaCaT_Human2.08670306
18ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.97252123
19WT1_19549856_ChIP-ChIP_CCG9911_Human1.89887644
20CTBP2_25329375_ChIP-Seq_LNCAP_Human1.89079089
21MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.85285886
22CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.83324001
23STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.82351083
24SMAD4_21799915_ChIP-Seq_A2780_Human1.81467023
25GATA1_22025678_ChIP-Seq_K562_Human1.81302416
26* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.77519214
27ELK1_19687146_ChIP-ChIP_HELA_Human1.77352933
28FUS_26573619_Chip-Seq_HEK293_Human1.72850305
29IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.72681627
30* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.72008855
31PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.71811715
32VDR_22108803_ChIP-Seq_LS180_Human1.64114122
33PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.61735071
34BRD4_25478319_ChIP-Seq_HGPS_Human1.61377420
35ZNF274_21170338_ChIP-Seq_K562_Hela1.60100391
36SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.57700397
37CTBP1_25329375_ChIP-Seq_LNCAP_Human1.55671403
38SMAD3_21741376_ChIP-Seq_EPCs_Human1.55036070
39DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.54803287
40GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.53804683
41EWS_26573619_Chip-Seq_HEK293_Human1.50671847
42* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.49986957
43IRF8_21731497_ChIP-ChIP_J774_Mouse1.48926476
44* SALL4_18804426_ChIP-ChIP_XEN_Mouse1.45899757
45UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.45013502
46E2F4_17652178_ChIP-ChIP_JURKAT_Human1.44378083
47AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.43537564
48* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.42129374
49NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.41552195
50STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.41228034
51ZNF217_24962896_ChIP-Seq_MCF-7_Human1.37208106
52PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.35682096
53* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.35034336
54FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.33583069
55PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.33271902
56AR_25329375_ChIP-Seq_VCAP_Human1.30597569
57IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.30463376
58SUZ12_27294783_Chip-Seq_NPCs_Mouse1.28735324
59* TCF4_23295773_ChIP-Seq_U87_Human1.27745895
60CBP_20019798_ChIP-Seq_JUKART_Human1.27027158
61IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.27027158
62FLI1_27457419_Chip-Seq_LIVER_Mouse1.26360084
63FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.25845127
64* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.24705427
65GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.23509435
66CBX2_27304074_Chip-Seq_ESCs_Mouse1.23121933
67TP53_18474530_ChIP-ChIP_U2OS_Human1.22144504
68NR3C1_21868756_ChIP-Seq_MCF10A_Human1.22082387
69PCGF2_27294783_Chip-Seq_ESCs_Mouse1.20876168
70BCAT_22108803_ChIP-Seq_LS180_Human1.20332000
71NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.19202300
72NRF2_20460467_ChIP-Seq_MEFs_Mouse1.19202300
73IRF8_27001747_Chip-Seq_BMDM_Mouse1.19019479
74NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.18886425
75ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.17709796
76EST1_17652178_ChIP-ChIP_JURKAT_Human1.16655074
77SOX9_26525672_Chip-Seq_HEART_Mouse1.15097448
78NFE2_27457419_Chip-Seq_LIVER_Mouse1.15004449
79HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.14915620
80ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.14630547
81SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.13765362
82SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.13765362
83E2F1_21310950_ChIP-Seq_MCF-7_Human1.13666722
84AHR_22903824_ChIP-Seq_MCF-7_Human1.13071949
85CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.13028492
86RUNX2_22187159_ChIP-Seq_PCA_Human1.12652985
87RNF2_27304074_Chip-Seq_NSC_Mouse1.12599237
88TCF4_22108803_ChIP-Seq_LS180_Human1.12454662
89RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.12144640
90MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.11890346
91TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.11577203
92POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.11577203
93TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.11513473
94TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10822808
95GABP_17652178_ChIP-ChIP_JURKAT_Human1.10488316
96MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.09468309
97TBX3_20139965_ChIP-Seq_MESCs_Mouse1.09360241
98TBX3_20139965_ChIP-Seq_ESCs_Mouse1.08875934
99SOX2_21211035_ChIP-Seq_LN229_Gbm1.08529005
100POU5F1_16153702_ChIP-ChIP_HESCs_Human1.08215309
101TRIM28_21343339_ChIP-Seq_HEK293_Human1.07347237
102PIAS1_25552417_ChIP-Seq_VCAP_Human1.07284801
103KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.06726240
104* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.06495123
105PCGF2_27294783_Chip-Seq_NPCs_Mouse1.06074492
106CDX2_19796622_ChIP-Seq_MESCs_Mouse1.05171578
107* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.04877313
108TP53_16413492_ChIP-PET_HCT116_Human1.04367394
109STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.04088993
110NANOG_18555785_Chip-Seq_ESCs_Mouse1.02976910
111PKCTHETA_26484144_Chip-Seq_BREAST_Human1.02611908
112SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.02446749
113CJUN_26792858_Chip-Seq_BT549_Human1.01943524
114TFEB_21752829_ChIP-Seq_HELA_Human1.00471810
115* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.98082575
116EZH2_27294783_Chip-Seq_NPCs_Mouse0.96538586
117* FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.95538675
118SMAD_19615063_ChIP-ChIP_OVARY_Human0.94591542
119FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.94459767
120SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.92956434
121GATA2_21666600_ChIP-Seq_HMVEC_Human0.92341259
122EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.90616741
123FOXM1_23109430_ChIP-Seq_U2OS_Human0.89987762
124PADI4_21655091_ChIP-ChIP_MCF-7_Human0.89714573
125MYB_26560356_Chip-Seq_TH2_Human0.89612935
126ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.89269152
127NFIB_24661679_ChIP-Seq_LUNG_Mouse0.89244090
128SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.89184051
129ER_23166858_ChIP-Seq_MCF-7_Human0.88646820
130SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.88134176
131MYB_26560356_Chip-Seq_TH1_Human0.88090150
132CMYC_18555785_Chip-Seq_ESCs_Mouse0.87030088
133KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.87017699
134KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.87017699
135KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.87017699
136TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.86977107
137ARNT_22903824_ChIP-Seq_MCF-7_Human0.86191389
138CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.85549987
139E2F1_18555785_Chip-Seq_ESCs_Mouse0.85443647
140FOXM1_26456572_ChIP-Seq_MCF-7_Human0.84950144
141RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.84782633
142FOXO3_23340844_ChIP-Seq_DLD1_Human0.84714250
143ISL1_27105846_Chip-Seq_CPCs_Mouse0.84652055
144EP300_21415370_ChIP-Seq_HL-1_Mouse0.83900794
145TCF4_18268006_ChIP-ChIP_LS174T_Human0.83643871
146VDR_24787735_ChIP-Seq_THP-1_Human0.83594381
147* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.83554417
148MYB_21317192_ChIP-Seq_ERMYB_Mouse0.83438761
149* STAT3_23295773_ChIP-Seq_U87_Human0.82600533
150SUZ12_18555785_Chip-Seq_ESCs_Mouse0.82232749
151P53_22387025_ChIP-Seq_ESCs_Mouse0.82083040
152RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.82017896

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation2.79110910
2MP0003136_yellow_coat_color2.67301857
3MP0002009_preneoplasia2.65046768
4MP0003121_genomic_imprinting2.63986020
5MP0002877_abnormal_melanocyte_morpholog2.44107527
6MP0003122_maternal_imprinting2.29826367
7MP0008438_abnormal_cutaneous_collagen2.29607739
8MP0006292_abnormal_olfactory_placode2.21101249
9MP0010030_abnormal_orbit_morphology2.08091073
10MP0008877_abnormal_DNA_methylation2.00022470
11MP0006054_spinal_hemorrhage1.97001053
12MP0003787_abnormal_imprinting1.94420174
13MP0005503_abnormal_tendon_morphology1.92423872
14MP0008057_abnormal_DNA_replication1.91488619
15MP0002938_white_spotting1.67563076
16MP0010307_abnormal_tumor_latency1.67498100
17MP0002233_abnormal_nose_morphology1.67449844
18MP0006072_abnormal_retinal_apoptosis1.64768292
19MP0005171_absent_coat_pigmentation1.63821476
20MP0004272_abnormal_basement_membrane1.63587074
21MP0000778_abnormal_nervous_system1.63292877
22MP0005623_abnormal_meninges_morphology1.61785758
23MP0003123_paternal_imprinting1.59605291
24MP0008007_abnormal_cellular_replicative1.58684835
25MP0004264_abnormal_extraembryonic_tissu1.57243693
26MP0003183_abnormal_peptide_metabolism1.55747179
27MP0002166_altered_tumor_susceptibility1.54971422
28MP0005187_abnormal_penis_morphology1.52258238
29MP0002102_abnormal_ear_morphology1.52074857
30MP0000631_abnormal_neuroendocrine_gland1.49282691
31MP0009780_abnormal_chondrocyte_physiolo1.48255352
32MP0000647_abnormal_sebaceous_gland1.47479790
33MP0005367_renal/urinary_system_phenotyp1.44820389
34MP0000516_abnormal_urinary_system1.44820389
35MP0005379_endocrine/exocrine_gland_phen1.43949422
36MP0005410_abnormal_fertilization1.42193502
37MP0003941_abnormal_skin_development1.41614260
38MP0003880_abnormal_central_pattern1.39817266
39MP0005076_abnormal_cell_differentiation1.38835032
40MP0001293_anophthalmia1.33841346
41MP0004808_abnormal_hematopoietic_stem1.33391593
42MP0003943_abnormal_hepatobiliary_system1.31565939
43MP0000428_abnormal_craniofacial_morphol1.31296471
44MP0003937_abnormal_limbs/digits/tail_de1.30169596
45MP0003300_gastrointestinal_ulcer1.29265025
46MP0002095_abnormal_skin_pigmentation1.25532592
47MP0001299_abnormal_eye_distance/1.25145095
48MP0003755_abnormal_palate_morphology1.22851400
49MP0005257_abnormal_intraocular_pressure1.22444290
50MP0003566_abnormal_cell_adhesion1.20508664
51MP0002163_abnormal_gland_morphology1.19320177
52MP0002006_tumorigenesis1.19309002
53MP0000383_abnormal_hair_follicle1.14795096
54MP0002837_dystrophic_cardiac_calcinosis1.13560221
55MP0000733_abnormal_muscle_development1.13224218
56MP0003567_abnormal_fetal_cardiomyocyte1.13118712
57MP0002928_abnormal_bile_duct1.12543481
58MP0001984_abnormal_olfaction1.12044693
59MP0000372_irregular_coat_pigmentation1.12014169
60MP0010352_gastrointestinal_tract_polyps1.09519646
61MP0000003_abnormal_adipose_tissue1.08076678
62MP0000013_abnormal_adipose_tissue1.06935879
63MP0000534_abnormal_ureter_morphology1.06854265
64MP0005058_abnormal_lysosome_morphology1.06261633
65MP0005391_vision/eye_phenotype1.04540247
66MP0005408_hypopigmentation1.04502980
67MP0010094_abnormal_chromosome_stability1.04461626
68MP0002177_abnormal_outer_ear1.02916062
69MP0000537_abnormal_urethra_morphology1.02861428
70MP0010678_abnormal_skin_adnexa1.01537283
71MP0000432_abnormal_head_morphology1.01535278
72MP0000639_abnormal_adrenal_gland1.01373690
73MP0003890_abnormal_embryonic-extraembry1.00158443
74MP0005253_abnormal_eye_physiology0.99682154
75MP0003935_abnormal_craniofacial_develop0.99388502
76MP0003385_abnormal_body_wall0.98826275
77MP0002909_abnormal_adrenal_gland0.98452145
78MP0004197_abnormal_fetal_growth/weight/0.98210379
79MP0002084_abnormal_developmental_patter0.97295317
80MP0002234_abnormal_pharynx_morphology0.96471943
81MP0000762_abnormal_tongue_morphology0.96097996
82MP0010368_abnormal_lymphatic_system0.95768676
83MP0004133_heterotaxia0.94673526
84MP0003283_abnormal_digestive_organ0.94539046
85MP0003077_abnormal_cell_cycle0.94416443
86MP0008995_early_reproductive_senescence0.94080398
87MP0001835_abnormal_antigen_presentation0.93845031
88MP0005551_abnormal_eye_electrophysiolog0.93645507
89MP0009250_abnormal_appendicular_skeleto0.92939339
90MP0005275_abnormal_skin_tensile0.92046179
91MP0003942_abnormal_urinary_system0.91306185
92MP0002282_abnormal_trachea_morphology0.91067706
93MP0003936_abnormal_reproductive_system0.91035190
94MP0002653_abnormal_ependyma_morphology0.90695612
95MP0008775_abnormal_heart_ventricle0.90575222
96MP0003045_fibrosis0.89811854
97MP0002092_abnormal_eye_morphology0.89758252
98MP0001346_abnormal_lacrimal_gland0.89377181
99MP0000371_diluted_coat_color0.89081853
100MP0003786_premature_aging0.88825178
101MP0003984_embryonic_growth_retardation0.88800809
102MP0002086_abnormal_extraembryonic_tissu0.88530859
103MP0009703_decreased_birth_body0.88490458
104MP0002160_abnormal_reproductive_system0.88452014
105MP0001879_abnormal_lymphatic_vessel0.88172653
106MP0003279_aneurysm0.88151192
107MP0002697_abnormal_eye_size0.87937907
108MP0002925_abnormal_cardiovascular_devel0.87620748
109MP0008058_abnormal_DNA_repair0.87016323
110MP0000653_abnormal_sex_gland0.86963788
111MP0005248_abnormal_Harderian_gland0.86798371
112MP0002088_abnormal_embryonic_growth/wei0.86631610
113MP0000015_abnormal_ear_pigmentation0.85813849
114MP0008961_abnormal_basal_metabolism0.85668053
115MP0002396_abnormal_hematopoietic_system0.85554931
116MP0004215_abnormal_myocardial_fiber0.85497131
117MP0008789_abnormal_olfactory_epithelium0.85247876
118MP0010386_abnormal_urinary_bladder0.85163552
119MP0005508_abnormal_skeleton_morphology0.84998873
120MP0005084_abnormal_gallbladder_morpholo0.83573694
121MP0003091_abnormal_cell_migration0.83499295
122MP0001145_abnormal_male_reproductive0.83311532
123MP0002896_abnormal_bone_mineralization0.83281249
124MP0000566_synostosis0.83209753
125MP0002109_abnormal_limb_morphology0.82788176
126MP0000462_abnormal_digestive_system0.82768335
127MP0001929_abnormal_gametogenesis0.82091543
128MP0003119_abnormal_digestive_system0.82051942
129MP0003861_abnormal_nervous_system0.81951558
130MP0009384_cardiac_valve_regurgitation0.81569184
131MP0009697_abnormal_copulation0.80356660
132MP0002932_abnormal_joint_morphology0.80264982
133MP0002116_abnormal_craniofacial_bone0.80163257
134MP0001944_abnormal_pancreas_morphology0.79669839
135MP0000678_abnormal_parathyroid_gland0.78699149
136MP0003950_abnormal_plasma_membrane0.78530328
137MP0001915_intracranial_hemorrhage0.78482277
138MP0005380_embryogenesis_phenotype0.78433396
139MP0001672_abnormal_embryogenesis/_devel0.78433396
140MP0005220_abnormal_exocrine_pancreas0.78227328
141MP0002210_abnormal_sex_determination0.77396953
142MP0004134_abnormal_chest_morphology0.77263506
143MP0000767_abnormal_smooth_muscle0.76032494
144MP0003828_pulmonary_edema0.75428757
145MP0001286_abnormal_eye_development0.75255722
146MP0005174_abnormal_tail_pigmentation0.73403817
147MP0000427_abnormal_hair_cycle0.73161622
148MP0002085_abnormal_embryonic_tissue0.73084585

Predicted human phenotypes

RankGene SetZ-score
1Volvulus (HP:0002580)3.42891163
2Abnormality of the nasal septum (HP:0000419)2.92319567
3Abnormality of the fingertips (HP:0001211)2.92071709
4Medial flaring of the eyebrow (HP:0010747)2.79423463
5Absent frontal sinuses (HP:0002688)2.70136389
6Bifid tongue (HP:0010297)2.69950156
7Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.68164002
8Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)2.66818618
911 pairs of ribs (HP:0000878)2.53175266
10Congenital primary aphakia (HP:0007707)2.49941180
11Acute myeloid leukemia (HP:0004808)2.46549990
12Spinal cord lesions (HP:0100561)2.38552113
13Syringomyelia (HP:0003396)2.38552113
14Abnormality of the frontal sinuses (HP:0002687)2.36321275
15Abnormality of the renal cortex (HP:0011035)2.35995265
16Genital tract atresia (HP:0001827)2.34247671
17Gait imbalance (HP:0002141)2.34058581
18Vaginal atresia (HP:0000148)2.29988735
19Chronic bronchitis (HP:0004469)2.25646912
20Renal cortical cysts (HP:0000803)2.24833544
21Lip pit (HP:0100267)2.23678590
22Nephrogenic diabetes insipidus (HP:0009806)2.20364062
23Prostate neoplasm (HP:0100787)2.19414705
24Short nail (HP:0001799)2.19217714
25True hermaphroditism (HP:0010459)2.17444793
26Poor coordination (HP:0002370)2.15357575
27Osteolytic defects of the hand bones (HP:0009699)2.14778902
28Osteolytic defects of the phalanges of the hand (HP:0009771)2.14778902
29Hypoplastic labia majora (HP:0000059)2.14524318
30Truncal obesity (HP:0001956)2.13556718
31Cervical subluxation (HP:0003308)2.13337521
32Chromsome breakage (HP:0040012)2.11079559
33Aplasia/Hypoplasia of the uvula (HP:0010293)2.09005203
34Preaxial foot polydactyly (HP:0001841)2.08470843
35Missing ribs (HP:0000921)2.07919426
36Abnormality of chromosome stability (HP:0003220)2.07404740
37Aplasia/Hypoplasia of the tibia (HP:0005772)2.06772113
38Broad face (HP:0000283)2.03740985
39Nephronophthisis (HP:0000090)2.03733754
40Spondylolisthesis (HP:0003302)2.02331461
41Adrenal hypoplasia (HP:0000835)2.01458948
42Aplasia/Hypoplasia involving the sinuses (HP:0009120)2.01440697
43Abnormal pancreas size (HP:0012094)2.00170147
44Postaxial hand polydactyly (HP:0001162)1.98719803
45Subacute progressive viral hepatitis (HP:0006572)1.98393037
46Nephroblastoma (Wilms tumor) (HP:0002667)1.98356272
47Tubulointerstitial nephritis (HP:0001970)1.97298813
48Long eyelashes (HP:0000527)1.96970651
49Dynein arm defect of respiratory motile cilia (HP:0012255)1.96713835
50Absent/shortened dynein arms (HP:0200106)1.96713835
51Median cleft lip (HP:0000161)1.96474784
52Postaxial foot polydactyly (HP:0001830)1.96195072
53Gastrointestinal atresia (HP:0002589)1.96133008
54Abnormality of the renal medulla (HP:0100957)1.95875070
55Papillary thyroid carcinoma (HP:0002895)1.95314480
56Short tibia (HP:0005736)1.95134494
57Subaortic stenosis (HP:0001682)1.94037076
58Abnormality of the left ventricular outflow tract (HP:0011103)1.94037076
59Metaphyseal dysplasia (HP:0100255)1.92507985
60Abnormality of the labia majora (HP:0012881)1.91639231
61Embryonal renal neoplasm (HP:0011794)1.91269491
62Oligodactyly (hands) (HP:0001180)1.90825038
63Hematochezia (HP:0002573)1.89676446
64Pancreatic islet-cell hyperplasia (HP:0004510)1.88254406
65Broad thumb (HP:0011304)1.88210456
66Decreased testicular size (HP:0008734)1.88023780
67Deep philtrum (HP:0002002)1.87956571
68Tubular atrophy (HP:0000092)1.87523033
69Reticulocytopenia (HP:0001896)1.87351813
70Rhinitis (HP:0012384)1.86338755
71Anophthalmia (HP:0000528)1.84779793
72Male pseudohermaphroditism (HP:0000037)1.84237130
73Arterial tortuosity (HP:0005116)1.84018167
74Fair hair (HP:0002286)1.83316187
75Hypothermia (HP:0002045)1.82020457
76Limited elbow extension (HP:0001377)1.80962778
77Calf muscle hypertrophy (HP:0008981)1.79838391
78Chronic hepatic failure (HP:0100626)1.78757668
79Hypoplastic ischia (HP:0003175)1.78731167
80Spinal muscular atrophy (HP:0007269)1.77629864
81Limited hip movement (HP:0008800)1.77397321
82Neoplasm of the oral cavity (HP:0100649)1.77274796
83Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.76569542
84Short 4th metacarpal (HP:0010044)1.76569542
85Macroorchidism (HP:0000053)1.74915721
86Chromosomal breakage induced by crosslinking agents (HP:0003221)1.74901622
87Ectopic kidney (HP:0000086)1.74851202
88Optic nerve hypoplasia (HP:0000609)1.74578789
89Broad phalanges of the hand (HP:0009768)1.74420243
90Abnormal respiratory motile cilium physiology (HP:0012261)1.73863469
91Esophageal atresia (HP:0002032)1.73312825
92Bell-shaped thorax (HP:0001591)1.72988698
93Vascular tortuosity (HP:0004948)1.72705238
94Abnormal sex determination (HP:0012244)1.72259782
95Sex reversal (HP:0012245)1.72259782
96Abnormality of the ischium (HP:0003174)1.72160507
97Micronodular cirrhosis (HP:0001413)1.72110622
98Pancreatic fibrosis (HP:0100732)1.72071673
99Sclerocornea (HP:0000647)1.71456326
100Gonadotropin excess (HP:0000837)1.71366749
101Colon cancer (HP:0003003)1.70224307
102Broad foot (HP:0001769)1.68536695
103Bronchitis (HP:0012387)1.68255077
104Supernumerary spleens (HP:0009799)1.68184258
105Broad phalanx (HP:0006009)1.68100111
106Fibular hypoplasia (HP:0003038)1.67284708
107Preaxial hand polydactyly (HP:0001177)1.66100649
108Vertebral clefting (HP:0008428)1.66043651
109Intestinal atresia (HP:0011100)1.65950123
110Labial hypoplasia (HP:0000066)1.65858665
111Short foot (HP:0001773)1.65657183
112Thyroid carcinoma (HP:0002890)1.65509736
113Dislocated radial head (HP:0003083)1.65075451
114Renal hypoplasia (HP:0000089)1.63965711
115Cystic liver disease (HP:0006706)1.63552764
116Bronchiectasis (HP:0002110)1.63246625
117Wormian bones (HP:0002645)1.62859821
118Prominent nasal bridge (HP:0000426)1.62576479
119Astigmatism (HP:0000483)1.62048121
120Broad finger (HP:0001500)1.61676975
121Micropenis (HP:0000054)1.58545724
122Increased circulating renin level (HP:0000848)1.57794839
123Hypoplastic female external genitalia (HP:0012815)1.56976908
124Optic nerve coloboma (HP:0000588)1.56951096
125Exotropia (HP:0000577)1.56893186
126Hyperinsulinemic hypoglycemia (HP:0000825)1.56853517
127Abnormality of dentin (HP:0010299)1.56351161
128Broad long bones (HP:0005622)1.56328059
129Abnormality of the right ventricle (HP:0001707)1.55600650
130Disproportionate short-trunk short stature (HP:0003521)1.55427865
131Abnormal vertebral ossification (HP:0100569)1.55409775
132Thick eyebrow (HP:0000574)1.55104922
133Deviation of the thumb (HP:0009603)1.54056615
134Short humerus (HP:0005792)1.53748588
135Increased number of teeth (HP:0011069)1.53619481
136Absent eyebrow (HP:0002223)1.53594081
137Overlapping toe (HP:0001845)1.53273635
138Epiphyseal dysplasia (HP:0002656)1.53184499
139Widely spaced teeth (HP:0000687)1.52852907
140Insulin-resistant diabetes mellitus (HP:0000831)1.52776341
141Meckel diverticulum (HP:0002245)1.52723148
142Abnormality of DNA repair (HP:0003254)1.52706107
143Generalized hypopigmentation of hair (HP:0011358)1.52436770
144Abnormality of the corticospinal tract (HP:0002492)1.52291416
145Flared iliac wings (HP:0002869)1.51581892
146Degeneration of the lateral corticospinal tracts (HP:0002314)1.51200314
147Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.51200314
148Broad-based gait (HP:0002136)1.51015683
149Tracheomalacia (HP:0002779)1.50940891
150Cutaneous finger syndactyly (HP:0010554)1.50827980
151Abnormality of midbrain morphology (HP:0002418)1.50641396
152Molar tooth sign on MRI (HP:0002419)1.50641396
153Abnormality of the radial head (HP:0003995)1.50619330
154Abnormal biliary tract physiology (HP:0012439)1.50596934
155Bile duct proliferation (HP:0001408)1.50596934
156Abnormality of the labia minora (HP:0012880)1.50400350
157Aplasia/Hypoplasia of the tongue (HP:0010295)1.50327250
158Synophrys (HP:0000664)1.49108028
159Stomach cancer (HP:0012126)1.48824300
160Abnormal spermatogenesis (HP:0008669)1.48272735
161Low anterior hairline (HP:0000294)1.48107842
162Hypoglycemic seizures (HP:0002173)1.47517016
163Soft skin (HP:0000977)1.47494372
164Mesomelia (HP:0003027)1.45330735
165White forelock (HP:0002211)1.44592976
166Trigonocephaly (HP:0000243)1.43846868
167Pancreatic cysts (HP:0001737)1.43175018
168Hypoplasia of the iris (HP:0007676)1.43079907
169Exostoses (HP:0100777)1.42274414
170Submucous cleft hard palate (HP:0000176)1.40769949
171Midline defect of the nose (HP:0004122)1.39199206

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PNCK2.94552727
2FRK2.94340645
3CDK122.74484281
4CASK2.64073294
5TNIK2.55771446
6LATS12.55039568
7ZAK2.50648733
8PASK2.47772014
9NUAK12.35682776
10INSRR2.33833011
11STK32.17376051
12WNK32.10234600
13BRD42.01123935
14WNK12.01059069
15MAPK151.92823581
16PLK21.86470877
17PRKD31.79946798
18TRIM281.71644213
19EPHA31.67410693
20FGFR21.64354762
21PLK41.61853844
22NLK1.51024283
23WNK41.43870378
24NEK91.43434792
25MAP3K41.42827091
26CHUK1.39439914
27MAP3K141.37057610
28WEE11.34481332
29FLT31.33645677
30NEK21.33121566
31STK391.31330008
32BRSK21.30430596
33MST41.30135348
34CAMK1D1.29829911
35MST1R1.28082859
36TAOK31.26368028
37MKNK11.25603202
38DMPK1.23408622
39BCR1.22291297
40HIPK21.21982189
41CDK61.17270325
42ATR1.16950277
43AKT31.15786070
44JAK31.12674074
45PIK3CG1.11044589
46TYK21.09509444
47CDC71.08209486
48NEK61.06607734
49STK161.05272099
50IRAK41.03249121
51JAK11.02885928
52RPS6KA51.02769387
53EPHA41.02614260
54FER1.02524162
55EPHA21.02387673
56STK241.02191662
57PDGFRB1.01722926
58TAF11.00360838
59EPHB11.00235570
60PDGFRA0.99668843
61ATM0.98165195
62RPS6KB20.96677014
63TRPM70.96523419
64MAP3K120.96129944
65MET0.95062924
66PAK30.94660368
67EPHB20.93588394
68TEC0.93584906
69KIT0.93119556
70SRPK10.92337823
71OXSR10.92323984
72FGFR30.91052297
73EIF2AK10.90393740
74MTOR0.89835489
75CAMK1G0.88978178
76ERBB40.87343232
77STK40.86853856
78IRAK10.86246074
79STK100.86241646
80CDK90.84950029
81YES10.78850029
82SCYL20.76919374
83MELK0.76139020
84MUSK0.76059325
85MKNK20.74944738
86PBK0.74770877
87PRKCE0.73630633
88EIF2AK30.72687425
89PIM10.71998073
90SGK20.71647899
91PLK30.70950204
92RPS6KA40.70912496
93PLK10.70734756
94PTK60.70572371
95IKBKB0.70343691
96CHEK10.70225953
97NEK10.69315266
98MAP3K20.68392402
99IKBKE0.68172325
100EIF2AK20.65562833
101TTK0.64543235
102ERBB30.64118171
103CSNK1A1L0.63795086
104MYLK0.60415725
105TGFBR10.59533891
106PAK20.59485013
107CSNK1G10.58337496
108FGFR10.56930486
109CHEK20.56157282
110STK38L0.54679578
111SGK30.53863081
112PKN20.53617861
113CDK30.53389302
114CDK70.52449386
115CAMK2D0.51462402
116TXK0.50591695
117MAPK10.50535208
118AURKB0.50384457
119MAPKAPK50.50368493
120CCNB10.50053324
121CDK80.49550034
122PIK3CA0.49303605
123MAP3K70.48099381
124AKT10.48078481
125VRK10.47845197
126STK380.47775358
127MAP4K20.47113692
128INSR0.46976180
129PTK20.45962835
130DYRK30.45855919
131DYRK1B0.45542214
132CSNK1E0.45506310
133PRKDC0.45420008
134PTK2B0.44986476
135MAPK140.44929374
136VRK20.44781080
137BMPR1B0.44266784
138PRKACB0.42983639
139ITK0.42428143
140NTRK30.41863294
141SGK2230.41448610
142SGK4940.41448610
143KSR10.41384593
144TSSK60.41229020
145PHKG10.39681365
146PHKG20.39681365

Predicted pathways (KEGG)

RankGene SetZ-score
1Propanoate metabolism_Homo sapiens_hsa006402.76722047
2Protein export_Homo sapiens_hsa030602.40729316
3Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.15873790
4Maturity onset diabetes of the young_Homo sapiens_hsa049501.94184468
5Circadian rhythm_Homo sapiens_hsa047101.90991252
6Non-homologous end-joining_Homo sapiens_hsa034501.89225029
7Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.76804245
8Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.74970695
9Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.72824213
10Selenocompound metabolism_Homo sapiens_hsa004501.65546529
11Antigen processing and presentation_Homo sapiens_hsa046121.62909011
12NF-kappa B signaling pathway_Homo sapiens_hsa040641.49562665
13Transcriptional misregulation in cancer_Homo sapiens_hsa052021.48315093
14Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.48082593
15Regulation of autophagy_Homo sapiens_hsa041401.40786612
16Adherens junction_Homo sapiens_hsa045201.40603262
17Prostate cancer_Homo sapiens_hsa052151.37864683
18Measles_Homo sapiens_hsa051621.35046188
19Cell cycle_Homo sapiens_hsa041101.32567608
20MicroRNAs in cancer_Homo sapiens_hsa052061.30459926
21ECM-receptor interaction_Homo sapiens_hsa045121.29570217
22Butanoate metabolism_Homo sapiens_hsa006501.28055152
23Systemic lupus erythematosus_Homo sapiens_hsa053221.27339625
24Viral carcinogenesis_Homo sapiens_hsa052031.25211957
25Ribosome_Homo sapiens_hsa030101.24099008
26Allograft rejection_Homo sapiens_hsa053301.23632415
27Small cell lung cancer_Homo sapiens_hsa052221.22235901
28Herpes simplex infection_Homo sapiens_hsa051681.21374155
29NOD-like receptor signaling pathway_Homo sapiens_hsa046211.19433507
30Toxoplasmosis_Homo sapiens_hsa051451.19128887
31Steroid biosynthesis_Homo sapiens_hsa001001.15748727
32TGF-beta signaling pathway_Homo sapiens_hsa043501.15646646
33Type I diabetes mellitus_Homo sapiens_hsa049401.15203126
34Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.11971164
35Toll-like receptor signaling pathway_Homo sapiens_hsa046201.11834780
36RNA polymerase_Homo sapiens_hsa030201.11314714
37Fanconi anemia pathway_Homo sapiens_hsa034601.10820161
38Basal transcription factors_Homo sapiens_hsa030221.09590314
39Influenza A_Homo sapiens_hsa051641.05241404
40RNA degradation_Homo sapiens_hsa030181.04944065
41mRNA surveillance pathway_Homo sapiens_hsa030151.02538532
42Folate biosynthesis_Homo sapiens_hsa007901.01729479
43Glycosaminoglycan degradation_Homo sapiens_hsa005310.99820751
44Focal adhesion_Homo sapiens_hsa045100.99763971
45Legionellosis_Homo sapiens_hsa051340.99477416
46Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.98989162
47Leishmaniasis_Homo sapiens_hsa051400.98970188
48Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.96930295
49Osteoclast differentiation_Homo sapiens_hsa043800.96663970
50Jak-STAT signaling pathway_Homo sapiens_hsa046300.96078324
51Hepatitis B_Homo sapiens_hsa051610.96022385
52Proteoglycans in cancer_Homo sapiens_hsa052050.95804014
53Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.94718684
54One carbon pool by folate_Homo sapiens_hsa006700.94494600
55RNA transport_Homo sapiens_hsa030130.94397037
56Chronic myeloid leukemia_Homo sapiens_hsa052200.94054832
57Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.93976109
58Nitrogen metabolism_Homo sapiens_hsa009100.93092785
59p53 signaling pathway_Homo sapiens_hsa041150.92743269
60RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.92285195
61Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.91949087
62Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.90686174
63Malaria_Homo sapiens_hsa051440.90559958
64Axon guidance_Homo sapiens_hsa043600.90309295
65HTLV-I infection_Homo sapiens_hsa051660.89237745
66DNA replication_Homo sapiens_hsa030300.86841629
67Leukocyte transendothelial migration_Homo sapiens_hsa046700.86072729
68TNF signaling pathway_Homo sapiens_hsa046680.85982179
69Lysosome_Homo sapiens_hsa041420.85949597
70beta-Alanine metabolism_Homo sapiens_hsa004100.84671276
71Homologous recombination_Homo sapiens_hsa034400.84552578
72Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.84474674
73Hippo signaling pathway_Homo sapiens_hsa043900.84300983
74Phototransduction_Homo sapiens_hsa047440.83815889
75Pathways in cancer_Homo sapiens_hsa052000.83500404
76Hematopoietic cell lineage_Homo sapiens_hsa046400.83321123
77Purine metabolism_Homo sapiens_hsa002300.83081198
78Pyruvate metabolism_Homo sapiens_hsa006200.82737835
79Thyroid cancer_Homo sapiens_hsa052160.81387206
80B cell receptor signaling pathway_Homo sapiens_hsa046620.80624219
81PI3K-Akt signaling pathway_Homo sapiens_hsa041510.80270961
82Graft-versus-host disease_Homo sapiens_hsa053320.79090588
83SNARE interactions in vesicular transport_Homo sapiens_hsa041300.79064935
84Oxidative phosphorylation_Homo sapiens_hsa001900.78848038
85Autoimmune thyroid disease_Homo sapiens_hsa053200.77733206
86Dorso-ventral axis formation_Homo sapiens_hsa043200.77699770
87Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.77355770
88Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.77218480
89Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.76859078
90Type II diabetes mellitus_Homo sapiens_hsa049300.76679179
91Insulin secretion_Homo sapiens_hsa049110.76593990
92FoxO signaling pathway_Homo sapiens_hsa040680.75939251
93Apoptosis_Homo sapiens_hsa042100.75889809
94Pancreatic cancer_Homo sapiens_hsa052120.75866214
95Epstein-Barr virus infection_Homo sapiens_hsa051690.75672435
96Peroxisome_Homo sapiens_hsa041460.74510984
97Base excision repair_Homo sapiens_hsa034100.74366424
98Huntingtons disease_Homo sapiens_hsa050160.74239500
99Alcoholism_Homo sapiens_hsa050340.72390925
100Viral myocarditis_Homo sapiens_hsa054160.70664162
101Renal cell carcinoma_Homo sapiens_hsa052110.70457291
102Mismatch repair_Homo sapiens_hsa034300.69327195
103Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.69067090
104Fatty acid metabolism_Homo sapiens_hsa012120.68769608
105Notch signaling pathway_Homo sapiens_hsa043300.68461064
106Thyroid hormone signaling pathway_Homo sapiens_hsa049190.68269113
107Oocyte meiosis_Homo sapiens_hsa041140.67741062
108Hedgehog signaling pathway_Homo sapiens_hsa043400.67671300
109Intestinal immune network for IgA production_Homo sapiens_hsa046720.67266245
110Basal cell carcinoma_Homo sapiens_hsa052170.67041302
111Wnt signaling pathway_Homo sapiens_hsa043100.66568336
112Amoebiasis_Homo sapiens_hsa051460.66556225
113Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.66479337
114Prolactin signaling pathway_Homo sapiens_hsa049170.66401466
115Tight junction_Homo sapiens_hsa045300.65341901
116AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.65233760
117Platelet activation_Homo sapiens_hsa046110.63599013
118Acute myeloid leukemia_Homo sapiens_hsa052210.62968222
119Steroid hormone biosynthesis_Homo sapiens_hsa001400.62868557
120Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.62713685
121Taste transduction_Homo sapiens_hsa047420.62630285
122Salmonella infection_Homo sapiens_hsa051320.62604857
123Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.62396086
124Protein digestion and absorption_Homo sapiens_hsa049740.62366911
125N-Glycan biosynthesis_Homo sapiens_hsa005100.61035805
126Melanoma_Homo sapiens_hsa052180.60980284
127Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.60911616
128Melanogenesis_Homo sapiens_hsa049160.60080076
129Hepatitis C_Homo sapiens_hsa051600.59073780
130ABC transporters_Homo sapiens_hsa020100.58830677
131Vitamin B6 metabolism_Homo sapiens_hsa007500.58758416
132Inositol phosphate metabolism_Homo sapiens_hsa005620.58461718
133Phagosome_Homo sapiens_hsa041450.57798168
134Regulation of actin cytoskeleton_Homo sapiens_hsa048100.57338976
135Parkinsons disease_Homo sapiens_hsa050120.57053412
136Lysine degradation_Homo sapiens_hsa003100.56287887
137Fatty acid elongation_Homo sapiens_hsa000620.56084355
138Spliceosome_Homo sapiens_hsa030400.56019664
139Pyrimidine metabolism_Homo sapiens_hsa002400.55614750
140Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.55514270
141Nucleotide excision repair_Homo sapiens_hsa034200.55107033
142Rheumatoid arthritis_Homo sapiens_hsa053230.55043900
143Cysteine and methionine metabolism_Homo sapiens_hsa002700.52900343
144Primary bile acid biosynthesis_Homo sapiens_hsa001200.52819804
145Colorectal cancer_Homo sapiens_hsa052100.52391135
146Alzheimers disease_Homo sapiens_hsa050100.51347387
147Thyroid hormone synthesis_Homo sapiens_hsa049180.49937695
148Glucagon signaling pathway_Homo sapiens_hsa049220.49675923
149Cardiac muscle contraction_Homo sapiens_hsa042600.47280416
150Dilated cardiomyopathy_Homo sapiens_hsa054140.46808857
151Fatty acid degradation_Homo sapiens_hsa000710.44985771
152Ether lipid metabolism_Homo sapiens_hsa005650.43510756
153Tryptophan metabolism_Homo sapiens_hsa003800.42353750
154Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.42268472
155Fatty acid biosynthesis_Homo sapiens_hsa000610.40678184
156Ovarian steroidogenesis_Homo sapiens_hsa049130.37749902
157Metabolic pathways_Homo sapiens_hsa011000.36402324
158Serotonergic synapse_Homo sapiens_hsa047260.35180106
159cGMP-PKG signaling pathway_Homo sapiens_hsa040220.34645488

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