Rank | Gene Set | Z-score |
---|---|---|
1 | astrocyte differentiation (GO:0048708) | 6.38652421 |
2 | locomotory exploration behavior (GO:0035641) | 6.21440467 |
3 | melanin biosynthetic process (GO:0042438) | 5.81799957 |
4 | eye photoreceptor cell differentiation (GO:0001754) | 5.57419190 |
5 | photoreceptor cell differentiation (GO:0046530) | 5.57419190 |
6 | L-amino acid import (GO:0043092) | 5.55373717 |
7 | presynaptic membrane organization (GO:0097090) | 5.54902815 |
8 | enteric nervous system development (GO:0048484) | 5.54386857 |
9 | melanin metabolic process (GO:0006582) | 5.27470553 |
10 | * dermatan sulfate biosynthetic process (GO:0030208) | 5.27353036 |
11 | amino acid import (GO:0043090) | 5.16991624 |
12 | alanine transport (GO:0032328) | 5.05748621 |
13 | secondary metabolite biosynthetic process (GO:0044550) | 4.97336640 |
14 | * dermatan sulfate metabolic process (GO:0030205) | 4.93347217 |
15 | cellular potassium ion homeostasis (GO:0030007) | 4.83803500 |
16 | neurotransmitter-gated ion channel clustering (GO:0072578) | 4.83436427 |
17 | cGMP-mediated signaling (GO:0019934) | 4.79885965 |
18 | sodium ion export (GO:0071436) | 4.71429008 |
19 | synaptic vesicle maturation (GO:0016188) | 4.54253424 |
20 | C4-dicarboxylate transport (GO:0015740) | 4.53957491 |
21 | nephron tubule formation (GO:0072079) | 4.53456798 |
22 | gamma-aminobutyric acid transport (GO:0015812) | 4.50602896 |
23 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 4.47760849 |
24 | neuron projection regeneration (GO:0031102) | 4.41073081 |
25 | * chondroitin sulfate catabolic process (GO:0030207) | 4.36334648 |
26 | glial cell differentiation (GO:0010001) | 4.33636538 |
27 | astrocyte development (GO:0014002) | 4.33525045 |
28 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 4.32083134 |
29 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 4.25832463 |
30 | neuron cell-cell adhesion (GO:0007158) | 4.15994100 |
31 | vocalization behavior (GO:0071625) | 4.13885552 |
32 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 4.12445207 |
33 | response to auditory stimulus (GO:0010996) | 4.09891100 |
34 | positive regulation of synaptic transmission, glutamatergic (GO:0051968) | 4.08133778 |
35 | exploration behavior (GO:0035640) | 4.07468787 |
36 | glial cell proliferation (GO:0014009) | 3.99429195 |
37 | cell communication by electrical coupling (GO:0010644) | 3.99382479 |
38 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 3.95290655 |
39 | negative regulation of astrocyte differentiation (GO:0048712) | 3.91741024 |
40 | glutamate secretion (GO:0014047) | 3.89453986 |
41 | transmission of nerve impulse (GO:0019226) | 3.86318436 |
42 | layer formation in cerebral cortex (GO:0021819) | 3.85197076 |
43 | synaptic vesicle exocytosis (GO:0016079) | 3.82592864 |
44 | regulation of synapse structural plasticity (GO:0051823) | 3.80969162 |
45 | positive regulation of osteoblast proliferation (GO:0033690) | 3.79657543 |
46 | proline transport (GO:0015824) | 3.77686303 |
47 | positive regulation of gliogenesis (GO:0014015) | 3.77132419 |
48 | auditory behavior (GO:0031223) | 3.75948218 |
49 | regulation of glutamate receptor signaling pathway (GO:1900449) | 3.74749488 |
50 | regulation of neuronal synaptic plasticity (GO:0048168) | 3.70406946 |
51 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 3.70283390 |
52 | axon ensheathment in central nervous system (GO:0032291) | 3.68722326 |
53 | central nervous system myelination (GO:0022010) | 3.68722326 |
54 | regulation of beta-amyloid formation (GO:1902003) | 3.68396467 |
55 | cellular response to cholesterol (GO:0071397) | 3.66697612 |
56 | synaptic transmission, glutamatergic (GO:0035249) | 3.65266074 |
57 | L-serine transport (GO:0015825) | 3.64444753 |
58 | glutamate receptor signaling pathway (GO:0007215) | 3.63868641 |
59 | axon regeneration (GO:0031103) | 3.62966658 |
60 | potassium ion import (GO:0010107) | 3.62511952 |
61 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.61490062 |
62 | regulation of neurotransmitter uptake (GO:0051580) | 3.59482807 |
63 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.56973412 |
64 | neuronal action potential propagation (GO:0019227) | 3.56742314 |
65 | response to dietary excess (GO:0002021) | 3.55424878 |
66 | regulation of synaptic vesicle exocytosis (GO:2000300) | 3.54085731 |
67 | cellular sodium ion homeostasis (GO:0006883) | 3.52275880 |
68 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 3.51531224 |
69 | positive regulation of inositol phosphate biosynthetic process (GO:0060732) | 3.49963695 |
70 | regulation of inclusion body assembly (GO:0090083) | 3.49233805 |
71 | neurotransmitter secretion (GO:0007269) | 3.48741528 |
72 | peripheral nervous system development (GO:0007422) | 3.48350457 |
73 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 3.46873154 |
74 | positive regulation of oligodendrocyte differentiation (GO:0048714) | 3.46619410 |
75 | regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 3.44395980 |
76 | acidic amino acid transport (GO:0015800) | 3.42768826 |
77 | cerebellar Purkinje cell layer development (GO:0021680) | 3.41581978 |
78 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 3.39916508 |
79 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 3.38144381 |
80 | negative regulation of sodium ion transport (GO:0010766) | 3.37128921 |
81 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 3.34801098 |
82 | regulation of respiratory system process (GO:0044065) | 3.33859864 |
83 | potassium ion homeostasis (GO:0055075) | 3.29543526 |
84 | membrane assembly (GO:0071709) | 3.29095139 |
85 | axon development (GO:0061564) | 3.28861751 |
86 | protein localization to synapse (GO:0035418) | 3.26946414 |
87 | hyperosmotic salinity response (GO:0042538) | 3.25976799 |
88 | neuromuscular process controlling balance (GO:0050885) | 3.24758218 |
89 | long-term memory (GO:0007616) | 3.23513917 |
90 | dendrite morphogenesis (GO:0048813) | 3.23410148 |
91 | one-carbon compound transport (GO:0019755) | 3.23376793 |
92 | regulation of amyloid precursor protein catabolic process (GO:1902991) | 3.22855647 |
93 | dendritic spine morphogenesis (GO:0060997) | 3.22607450 |
94 | postsynaptic membrane organization (GO:0001941) | 3.22383897 |
95 | heart valve formation (GO:0003188) | 3.20770353 |
96 | positive regulation of cellular amide metabolic process (GO:0034250) | 3.20279037 |
97 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 3.19910767 |
98 | neuronal ion channel clustering (GO:0045161) | 3.19766225 |
99 | Sertoli cell development (GO:0060009) | 3.18765213 |
100 | negative regulation of myoblast differentiation (GO:0045662) | 3.17867829 |
101 | long-term synaptic potentiation (GO:0060291) | 3.15892908 |
102 | regulation of phospholipid biosynthetic process (GO:0071071) | 3.12895953 |
103 | L-glutamate transport (GO:0015813) | 3.12743628 |
104 | negative regulation of neurotransmitter transport (GO:0051589) | 3.12125377 |
105 | regulation of synaptic vesicle transport (GO:1902803) | 3.11325108 |
106 | neuron-neuron synaptic transmission (GO:0007270) | 3.10303970 |
107 | positive regulation of neuroblast proliferation (GO:0002052) | 3.09940900 |
108 | peripheral nervous system axon ensheathment (GO:0032292) | 3.09462425 |
109 | myelination in peripheral nervous system (GO:0022011) | 3.09462425 |
110 | serine transport (GO:0032329) | 3.08585822 |
111 | cranial nerve development (GO:0021545) | 3.08317399 |
112 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 3.07723484 |
113 | positive regulation of potassium ion transmembrane transport (GO:1901381) | 3.07529375 |
114 | cerebellar granule cell differentiation (GO:0021707) | 3.07267114 |
115 | myelination (GO:0042552) | 3.04003749 |
116 | glycine transport (GO:0015816) | 3.02968945 |
117 | prepulse inhibition (GO:0060134) | 3.01756642 |
118 | endocardial cushion morphogenesis (GO:0003203) | 3.01051725 |
119 | neuronal stem cell maintenance (GO:0097150) | 2.99672402 |
120 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 2.99621328 |
121 | regulation of synaptic plasticity (GO:0048167) | 2.98923059 |
122 | cellular response to sterol (GO:0036315) | 2.97360779 |
123 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 2.96220859 |
124 | ensheathment of neurons (GO:0007272) | 2.95180532 |
125 | axon ensheathment (GO:0008366) | 2.95180532 |
126 | developmental induction (GO:0031128) | 2.94338015 |
127 | ovulation cycle (GO:0042698) | 2.93748074 |
128 | regulation of cholesterol biosynthetic process (GO:0045540) | 2.93456586 |
129 | membrane repolarization (GO:0086009) | 2.93256758 |
130 | neurotransmitter uptake (GO:0001504) | 2.93031883 |
131 | regulation of dendritic spine morphogenesis (GO:0061001) | 2.92453915 |
132 | cell-cell signaling involved in cell fate commitment (GO:0045168) | 2.92112283 |
133 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.91288611 |
134 | positive regulation of dendritic spine development (GO:0060999) | 2.90919989 |
135 | peptidyl-tyrosine autophosphorylation (GO:0038083) | 2.90291277 |
136 | neurotransmitter transport (GO:0006836) | 2.89949489 |
137 | regulation of gliogenesis (GO:0014013) | 2.88129968 |
138 | Notch signaling involved in heart development (GO:0061314) | 2.87719500 |
139 | cyclic-nucleotide-mediated signaling (GO:0019935) | 2.85441626 |
140 | regulation of astrocyte differentiation (GO:0048710) | 2.83014561 |
141 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 2.81655629 |
142 | negative regulation of oligodendrocyte differentiation (GO:0048715) | 2.81637109 |
143 | regulation of oligodendrocyte differentiation (GO:0048713) | 2.81585535 |
144 | innervation (GO:0060384) | 2.81418986 |
145 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 2.80830559 |
146 | regulation of neurotransmitter levels (GO:0001505) | 2.79594404 |
147 | presynaptic membrane assembly (GO:0097105) | 2.76341918 |
148 | mechanosensory behavior (GO:0007638) | 2.76320817 |
149 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 2.75788233 |
150 | positive regulation of membrane potential (GO:0045838) | 2.72803510 |
151 | oligodendrocyte differentiation (GO:0048709) | 2.71914630 |
152 | negative regulation of smoothened signaling pathway (GO:0045879) | 2.70524683 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.69214434 |
2 | * SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 3.18028480 |
3 | * SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 3.07965269 |
4 | * JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.92061514 |
5 | * SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.79008710 |
6 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.77045851 |
7 | * RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.73914614 |
8 | * EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.73914614 |
9 | * JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.68719313 |
10 | AR_21572438_ChIP-Seq_LNCaP_Human | 2.64697642 |
11 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.63848864 |
12 | * MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.63076056 |
13 | * SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.56994356 |
14 | * SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.56843799 |
15 | * SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.49081910 |
16 | * REST_21632747_ChIP-Seq_MESCs_Mouse | 2.47770814 |
17 | * EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.46431516 |
18 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.43330550 |
19 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.36675006 |
20 | * RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.36602967 |
21 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 2.34947361 |
22 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.23706598 |
23 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.20445931 |
24 | * SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.17451844 |
25 | * REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.93413271 |
26 | * EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.92699048 |
27 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.92566725 |
28 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.70827273 |
29 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.68640678 |
30 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.66746043 |
31 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.60625566 |
32 | * RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.55938257 |
33 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.49453429 |
34 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 1.49065997 |
35 | * PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.49007965 |
36 | * RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.47884066 |
37 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.47192251 |
38 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.42203632 |
39 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.41965121 |
40 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.37582720 |
41 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.33546554 |
42 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.32706619 |
43 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.29297606 |
44 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.28128972 |
45 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.27739384 |
46 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.27444217 |
47 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.26806481 |
48 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.26318735 |
49 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.25209015 |
50 | * POU5F1_16518401_ChIP-PET_MESCs_Mouse | 1.24469232 |
51 | * CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.23846107 |
52 | AR_19668381_ChIP-Seq_PC3_Human | 1.23373562 |
53 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.21731817 |
54 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.21334141 |
55 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.21272340 |
56 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.21084212 |
57 | * CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.20282722 |
58 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.20185786 |
59 | * RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.18989149 |
60 | * DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.18578937 |
61 | RXR_22108803_ChIP-Seq_LS180_Human | 1.17939391 |
62 | * RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.15587528 |
63 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.15196501 |
64 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.14372609 |
65 | * TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.13009807 |
66 | KDM2B_26808549_Chip-Seq_K562_Human | 1.12286720 |
67 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.11984485 |
68 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.11982611 |
69 | TP53_16413492_ChIP-PET_HCT116_Human | 1.11873382 |
70 | RUNX1_26923725_Chip-Seq_HPCs_Mouse | 1.10613848 |
71 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.10486753 |
72 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.08601643 |
73 | * MITF_21258399_ChIP-Seq_MELANOMA_Human | 1.08554908 |
74 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.08120012 |
75 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.07802685 |
76 | AR_25329375_ChIP-Seq_VCAP_Human | 1.07148027 |
77 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 1.06843099 |
78 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.06814064 |
79 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.06363221 |
80 | * LXR_22292898_ChIP-Seq_THP-1_Human | 1.06354853 |
81 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.05897618 |
82 | P300_19829295_ChIP-Seq_ESCs_Human | 1.04490044 |
83 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.03184189 |
84 | STAT3_23295773_ChIP-Seq_U87_Human | 1.02592377 |
85 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.01948110 |
86 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.01914581 |
87 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.01477788 |
88 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.00240197 |
89 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.97716205 |
90 | * TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.97027670 |
91 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 0.96768107 |
92 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.96651140 |
93 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.96523928 |
94 | ZNF274_21170338_ChIP-Seq_K562_Hela | 0.96022134 |
95 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 0.95485992 |
96 | SMC4_20622854_ChIP-Seq_HELA_Human | 0.95038572 |
97 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.94129913 |
98 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.93186061 |
99 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.93059890 |
100 | NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse | 0.92582961 |
101 | * TP53_23651856_ChIP-Seq_MEFs_Mouse | 0.92541869 |
102 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 0.92355127 |
103 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.90790429 |
104 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 0.90656508 |
105 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.90254856 |
106 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.90082479 |
107 | * TET1_21490601_ChIP-Seq_MESCs_Mouse | 0.89186876 |
108 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.88940142 |
109 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.88940142 |
110 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.88606004 |
111 | SOX3_22085726_ChIP-Seq_NPCs_Mouse | 0.88398339 |
112 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.88367131 |
113 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 0.87535998 |
114 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.87420877 |
115 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 0.87307338 |
116 | * CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.86823755 |
117 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.86662090 |
118 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.86074010 |
119 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.85355316 |
120 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 0.85182777 |
121 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.84406103 |
122 | * CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.84100109 |
123 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.83998991 |
124 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 0.83782982 |
125 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.83713192 |
126 | NANOG_18347094_ChIP-ChIP_MESCs_Mouse | 0.83457949 |
127 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 0.81445934 |
128 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 0.81445934 |
129 | CLOCK_20551151_ChIP-Seq_293T_Human | 0.80528828 |
130 | SOX9_26525672_Chip-Seq_HEART_Mouse | 0.79343663 |
131 | POU5F1_18347094_ChIP-ChIP_MESCs_Mouse | 0.79021803 |
132 | * SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.77853803 |
133 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 0.76825756 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 5.49808870 |
2 | * MP0003635_abnormal_synaptic_transmissio | 3.51303292 |
3 | MP0003880_abnormal_central_pattern | 3.29225391 |
4 | MP0003690_abnormal_glial_cell | 3.18179529 |
5 | MP0004858_abnormal_nervous_system | 3.14498404 |
6 | MP0001486_abnormal_startle_reflex | 3.06739245 |
7 | MP0003329_amyloid_beta_deposits | 3.00848821 |
8 | MP0004270_analgesia | 2.98968557 |
9 | MP0009745_abnormal_behavioral_response | 2.95155495 |
10 | MP0009379_abnormal_foot_pigmentation | 2.91305388 |
11 | MP0002064_seizures | 2.87845351 |
12 | MP0002063_abnormal_learning/memory/cond | 2.79306118 |
13 | MP0009046_muscle_twitch | 2.77836145 |
14 | MP0005423_abnormal_somatic_nervous | 2.75699821 |
15 | MP0004885_abnormal_endolymph | 2.57544626 |
16 | MP0000372_irregular_coat_pigmentation | 2.57211084 |
17 | MP0005646_abnormal_pituitary_gland | 2.53478235 |
18 | MP0002572_abnormal_emotion/affect_behav | 2.49231390 |
19 | MP0002822_catalepsy | 2.40615740 |
20 | MP0009780_abnormal_chondrocyte_physiolo | 2.27995759 |
21 | MP0008569_lethality_at_weaning | 2.16019290 |
22 | MP0002272_abnormal_nervous_system | 2.15647496 |
23 | MP0001968_abnormal_touch/_nociception | 2.13394853 |
24 | MP0001440_abnormal_grooming_behavior | 2.04775096 |
25 | MP0001984_abnormal_olfaction | 2.03102416 |
26 | MP0004381_abnormal_hair_follicle | 2.01864010 |
27 | MP0002734_abnormal_mechanical_nocicepti | 2.01629699 |
28 | MP0002733_abnormal_thermal_nociception | 1.94018638 |
29 | MP0000778_abnormal_nervous_system | 1.89537865 |
30 | MP0001502_abnormal_circadian_rhythm | 1.88183266 |
31 | MP0002095_abnormal_skin_pigmentation | 1.84782234 |
32 | MP0003634_abnormal_glial_cell | 1.83109218 |
33 | MP0002254_reproductive_system_inflammat | 1.82255116 |
34 | MP0002736_abnormal_nociception_after | 1.81245469 |
35 | MP0002557_abnormal_social/conspecific_i | 1.78682387 |
36 | MP0001501_abnormal_sleep_pattern | 1.78623017 |
37 | MP0002067_abnormal_sensory_capabilities | 1.75158597 |
38 | MP0002909_abnormal_adrenal_gland | 1.71803430 |
39 | MP0003075_altered_response_to | 1.63261222 |
40 | MP0001970_abnormal_pain_threshold | 1.61671102 |
41 | MP0003633_abnormal_nervous_system | 1.61541188 |
42 | MP0000604_amyloidosis | 1.54348525 |
43 | MP0000955_abnormal_spinal_cord | 1.50721637 |
44 | MP0000920_abnormal_myelination | 1.49439584 |
45 | MP0004142_abnormal_muscle_tone | 1.46006504 |
46 | MP0003632_abnormal_nervous_system | 1.44809850 |
47 | MP0003631_nervous_system_phenotype | 1.44029234 |
48 | MP0002882_abnormal_neuron_morphology | 1.41178503 |
49 | MP0005408_hypopigmentation | 1.39923031 |
50 | MP0005386_behavior/neurological_phenoty | 1.39212142 |
51 | MP0004924_abnormal_behavior | 1.39212142 |
52 | MP0000371_diluted_coat_color | 1.34762273 |
53 | MP0001485_abnormal_pinna_reflex | 1.32285062 |
54 | MP0003136_yellow_coat_color | 1.32285058 |
55 | MP0005174_abnormal_tail_pigmentation | 1.32125099 |
56 | MP0000579_abnormal_nail_morphology | 1.31030938 |
57 | MP0005645_abnormal_hypothalamus_physiol | 1.30458965 |
58 | MP0002066_abnormal_motor_capabilities/c | 1.29802364 |
59 | MP0005167_abnormal_blood-brain_barrier | 1.28877567 |
60 | MP0002653_abnormal_ependyma_morphology | 1.21285526 |
61 | MP0002184_abnormal_innervation | 1.19703150 |
62 | MP0005075_abnormal_melanosome_morpholog | 1.19440112 |
63 | MP0004811_abnormal_neuron_physiology | 1.18675990 |
64 | MP0002735_abnormal_chemical_nociception | 1.17548205 |
65 | MP0005257_abnormal_intraocular_pressure | 1.15612002 |
66 | * MP0002152_abnormal_brain_morphology | 1.15577099 |
67 | MP0005551_abnormal_eye_electrophysiolog | 1.15154695 |
68 | MP0001529_abnormal_vocalization | 1.14688291 |
69 | MP0001905_abnormal_dopamine_level | 1.12296870 |
70 | MP0002638_abnormal_pupillary_reflex | 1.12106174 |
71 | MP0002090_abnormal_vision | 1.11621239 |
72 | MP0003183_abnormal_peptide_metabolism | 1.07988397 |
73 | MP0001177_atelectasis | 1.06322640 |
74 | MP0005058_abnormal_lysosome_morphology | 1.05278659 |
75 | MP0005171_absent_coat_pigmentation | 1.04557454 |
76 | MP0002089_abnormal_postnatal_growth/wei | 1.04144192 |
77 | MP0001299_abnormal_eye_distance/ | 1.01757006 |
78 | MP0003137_abnormal_impulse_conducting | 1.01687501 |
79 | MP0002075_abnormal_coat/hair_pigmentati | 1.01094755 |
80 | MP0005623_abnormal_meninges_morphology | 1.00508872 |
81 | MP0009384_cardiac_valve_regurgitation | 0.98195379 |
82 | MP0001963_abnormal_hearing_physiology | 0.96078040 |
83 | MP0002229_neurodegeneration | 0.95055396 |
84 | MP0005379_endocrine/exocrine_gland_phen | 0.91388534 |
85 | MP0004742_abnormal_vestibular_system | 0.90981703 |
86 | MP0002938_white_spotting | 0.90173533 |
87 | MP0005253_abnormal_eye_physiology | 0.88400110 |
88 | MP0009840_abnormal_foam_cell | 0.88314877 |
89 | MP0003172_abnormal_lysosome_physiology | 0.88044935 |
90 | MP0003878_abnormal_ear_physiology | 0.87435221 |
91 | MP0005377_hearing/vestibular/ear_phenot | 0.87435221 |
92 | MP0000762_abnormal_tongue_morphology | 0.87004521 |
93 | MP0003283_abnormal_digestive_organ | 0.86296538 |
94 | MP0000569_abnormal_digit_pigmentation | 0.85971599 |
95 | MP0005595_abnormal_vascular_smooth | 0.82123587 |
96 | MP0002069_abnormal_eating/drinking_beha | 0.81446016 |
97 | MP0000631_abnormal_neuroendocrine_gland | 0.81052484 |
98 | MP0002752_abnormal_somatic_nervous | 0.80354083 |
99 | MP0000751_myopathy | 0.74412289 |
100 | MP0001186_pigmentation_phenotype | 0.74297319 |
101 | MP0003279_aneurysm | 0.74139345 |
102 | MP0006276_abnormal_autonomic_nervous | 0.73761180 |
103 | MP0001324_abnormal_eye_pigmentation | 0.72649911 |
104 | MP0002751_abnormal_autonomic_nervous | 0.72185208 |
105 | MP0001958_emphysema | 0.70069503 |
106 | MP0004215_abnormal_myocardial_fiber | 0.69800515 |
107 | MP0008874_decreased_physiological_sensi | 0.68539886 |
108 | MP0000566_synostosis | 0.68338767 |
109 | MP0000015_abnormal_ear_pigmentation | 0.67073878 |
110 | MP0000026_abnormal_inner_ear | 0.67008828 |
111 | MP0005391_vision/eye_phenotype | 0.64928645 |
112 | MP0004130_abnormal_muscle_cell | 0.62455007 |
113 | MP0005499_abnormal_olfactory_system | 0.61276113 |
114 | MP0005394_taste/olfaction_phenotype | 0.61276113 |
115 | MP0002249_abnormal_larynx_morphology | 0.60682620 |
116 | MP0003861_abnormal_nervous_system | 0.60130774 |
117 | MP0000647_abnormal_sebaceous_gland | 0.59663972 |
118 | MP0005166_decreased_susceptibility_to | 0.58554196 |
119 | MP0004043_abnormal_pH_regulation | 0.58106792 |
120 | MP0001943_abnormal_respiration | 0.57484819 |
121 | MP0008872_abnormal_physiological_respon | 0.57434330 |
122 | MP0008260_abnormal_autophagy | 0.56812690 |
123 | MP0000534_abnormal_ureter_morphology | 0.56776699 |
124 | MP0004085_abnormal_heartbeat | 0.56608492 |
125 | MP0003879_abnormal_hair_cell | 0.56607066 |
126 | MP0005248_abnormal_Harderian_gland | 0.55376132 |
127 | MP0000639_abnormal_adrenal_gland | 0.54042891 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Megalencephaly (HP:0001355) | 6.38877134 |
2 | White forelock (HP:0002211) | 5.82971101 |
3 | Myokymia (HP:0002411) | 5.35479077 |
4 | Patchy hypopigmentation of hair (HP:0011365) | 5.30590508 |
5 | Focal motor seizures (HP:0011153) | 5.21837014 |
6 | Aplasia involving bones of the upper limbs (HP:0009823) | 5.20251159 |
7 | Aplasia of the phalanges of the hand (HP:0009802) | 5.20251159 |
8 | Aplasia involving bones of the extremities (HP:0009825) | 5.20251159 |
9 | Neurofibrillary tangles (HP:0002185) | 5.09557347 |
10 | Morphological abnormality of the inner ear (HP:0011390) | 4.59421599 |
11 | Blue irides (HP:0000635) | 4.04947334 |
12 | Cerebral inclusion bodies (HP:0100314) | 4.00632930 |
13 | Focal seizures (HP:0007359) | 3.99206101 |
14 | Hemiparesis (HP:0001269) | 3.84834049 |
15 | Heterochromia iridis (HP:0001100) | 3.78117180 |
16 | Epileptic encephalopathy (HP:0200134) | 3.75800778 |
17 | Supranuclear gaze palsy (HP:0000605) | 3.75721248 |
18 | Action tremor (HP:0002345) | 3.64944299 |
19 | Abnormality of the diencephalon (HP:0010662) | 3.56798551 |
20 | Abnormality of binocular vision (HP:0011514) | 3.50265165 |
21 | Diplopia (HP:0000651) | 3.50265165 |
22 | Hemiplegia (HP:0002301) | 3.49750718 |
23 | Progressive cerebellar ataxia (HP:0002073) | 3.41805749 |
24 | Hypopigmentation of the fundus (HP:0007894) | 3.36056262 |
25 | Visual hallucinations (HP:0002367) | 3.13977766 |
26 | Anomalous pulmonary venous return (HP:0010772) | 3.06285630 |
27 | Dysdiadochokinesis (HP:0002075) | 3.05328405 |
28 | Clumsiness (HP:0002312) | 3.04318543 |
29 | Obstructive sleep apnea (HP:0002870) | 2.94359798 |
30 | Hypoplasia of the iris (HP:0007676) | 2.93623701 |
31 | Spastic paraparesis (HP:0002313) | 2.90858618 |
32 | Abnormality of the 4th metacarpal (HP:0010012) | 2.83695015 |
33 | Abnormal auditory evoked potentials (HP:0006958) | 2.82356246 |
34 | Ocular albinism (HP:0001107) | 2.81807371 |
35 | Postural instability (HP:0002172) | 2.78589361 |
36 | Abnormal eating behavior (HP:0100738) | 2.78217715 |
37 | Depression (HP:0000716) | 2.76458259 |
38 | Hyperacusis (HP:0010780) | 2.75577158 |
39 | Generalized tonic-clonic seizures (HP:0002069) | 2.72985221 |
40 | Split foot (HP:0001839) | 2.70774060 |
41 | Synostosis involving the elbow (HP:0003938) | 2.69002948 |
42 | Humeroradial synostosis (HP:0003041) | 2.69002948 |
43 | Intention tremor (HP:0002080) | 2.68474891 |
44 | Ankle clonus (HP:0011448) | 2.65233843 |
45 | Overriding aorta (HP:0002623) | 2.63586125 |
46 | Elfin facies (HP:0004428) | 2.63562451 |
47 | Abnormality of the pulmonary veins (HP:0011718) | 2.60844056 |
48 | Truncal ataxia (HP:0002078) | 2.59074568 |
49 | Atonic seizures (HP:0010819) | 2.58239755 |
50 | Abnormality of the ischium (HP:0003174) | 2.58211035 |
51 | Status epilepticus (HP:0002133) | 2.57414112 |
52 | Dysmetria (HP:0001310) | 2.56222883 |
53 | Abnormality of cochlea (HP:0000375) | 2.50593586 |
54 | Synostosis of carpal bones (HP:0005048) | 2.50533640 |
55 | Oligodactyly (HP:0012165) | 2.49570434 |
56 | Akinesia (HP:0002304) | 2.46707645 |
57 | Iris hypopigmentation (HP:0007730) | 2.45854938 |
58 | Cerebral hypomyelination (HP:0006808) | 2.45766400 |
59 | Febrile seizures (HP:0002373) | 2.42539461 |
60 | Absent epiphyses (HP:0010577) | 2.41972714 |
61 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 2.41972714 |
62 | Pseudobulbar signs (HP:0002200) | 2.40006135 |
63 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 2.38557882 |
64 | Mesangial abnormality (HP:0001966) | 2.37793805 |
65 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.34285497 |
66 | Abnormality of secondary sexual hair (HP:0009888) | 2.31874588 |
67 | Abnormality of the axillary hair (HP:0100134) | 2.31874588 |
68 | Dialeptic seizures (HP:0011146) | 2.31403473 |
69 | Bowel incontinence (HP:0002607) | 2.29789125 |
70 | Back pain (HP:0003418) | 2.27020612 |
71 | Lower limb muscle weakness (HP:0007340) | 2.23926514 |
72 | Hypoplastic left heart (HP:0004383) | 2.23856324 |
73 | Anxiety (HP:0000739) | 2.23268493 |
74 | Vertebral clefting (HP:0008428) | 2.22708749 |
75 | Bell-shaped thorax (HP:0001591) | 2.22545551 |
76 | Oligodactyly (hands) (HP:0001180) | 2.20826734 |
77 | Decreased lacrimation (HP:0000633) | 2.20391949 |
78 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.19008473 |
79 | Absence seizures (HP:0002121) | 2.17631273 |
80 | Truncus arteriosus (HP:0001660) | 2.17578455 |
81 | Congenital sensorineural hearing impairment (HP:0008527) | 2.14816234 |
82 | Insomnia (HP:0100785) | 2.14373205 |
83 | Hyperventilation (HP:0002883) | 2.12717804 |
84 | Adactyly (HP:0009776) | 2.12717693 |
85 | Hypoplastic ischia (HP:0003175) | 2.12545285 |
86 | Renovascular hypertension (HP:0100817) | 2.10873093 |
87 | Abnormality of the middle phalanges of the toes (HP:0010183) | 2.10142191 |
88 | Mixed hearing impairment (HP:0000410) | 2.08145374 |
89 | Stereotypic behavior (HP:0000733) | 2.07778457 |
90 | Abnormal large intestine physiology (HP:0012700) | 2.06601052 |
91 | Spastic gait (HP:0002064) | 2.05746530 |
92 | Fibular hypoplasia (HP:0003038) | 2.05336576 |
93 | Bradykinesia (HP:0002067) | 2.04735246 |
94 | Gaze-evoked nystagmus (HP:0000640) | 2.04137524 |
95 | Bronchomalacia (HP:0002780) | 2.04118312 |
96 | Rigidity (HP:0002063) | 2.02151412 |
97 | Polyphagia (HP:0002591) | 2.02141637 |
98 | Peripheral hypomyelination (HP:0007182) | 2.02066289 |
99 | Generalized hypopigmentation (HP:0007513) | 2.01351688 |
100 | Premature graying of hair (HP:0002216) | 1.99726998 |
101 | Rib fusion (HP:0000902) | 1.98027111 |
102 | Increased CSF protein (HP:0002922) | 1.96801804 |
103 | Ulnar claw (HP:0001178) | 1.96660681 |
104 | Abnormal social behavior (HP:0012433) | 1.96256826 |
105 | Impaired social interactions (HP:0000735) | 1.96256826 |
106 | Poor eye contact (HP:0000817) | 1.96188316 |
107 | Glossoptosis (HP:0000162) | 1.95427541 |
108 | Postural tremor (HP:0002174) | 1.95039217 |
109 | Aplasia/Hypoplasia of the macula (HP:0008059) | 1.94506639 |
110 | Metabolic alkalosis (HP:0200114) | 1.93540550 |
111 | Broad-based gait (HP:0002136) | 1.93123315 |
112 | Dementia (HP:0000726) | 1.91321121 |
113 | Shallow orbits (HP:0000586) | 1.90327158 |
114 | Increased circulating renin level (HP:0000848) | 1.87690600 |
115 | Anophthalmia (HP:0000528) | 1.87499826 |
116 | Neuronal loss in central nervous system (HP:0002529) | 1.86492720 |
117 | Hypoplastic nipples (HP:0002557) | 1.86255628 |
118 | Torticollis (HP:0000473) | 1.85863091 |
119 | Renal duplication (HP:0000075) | 1.84505482 |
120 | Hypsarrhythmia (HP:0002521) | 1.84504937 |
121 | Foot dorsiflexor weakness (HP:0009027) | 1.84446612 |
122 | Enlarged epiphyses (HP:0010580) | 1.84307686 |
123 | EEG with generalized epileptiform discharges (HP:0011198) | 1.83384428 |
124 | Aplasia/Hypoplasia affecting the retina (HP:0008061) | 1.82506961 |
125 | Missing ribs (HP:0000921) | 1.82432164 |
126 | Coronal craniosynostosis (HP:0004440) | 1.81953856 |
127 | Long nose (HP:0003189) | 1.80433129 |
128 | Laryngomalacia (HP:0001601) | 1.80311380 |
129 | Epileptiform EEG discharges (HP:0011182) | 1.79986536 |
130 | Tetraplegia (HP:0002445) | 1.79658144 |
131 | Supernumerary ribs (HP:0005815) | 1.79537729 |
132 | Urethral obstruction (HP:0000796) | 1.79311330 |
133 | Scanning speech (HP:0002168) | 1.78837449 |
134 | Flat cornea (HP:0007720) | 1.77784088 |
135 | Neoplasm of the oral cavity (HP:0100649) | 1.77506716 |
136 | Paraparesis (HP:0002385) | 1.77376862 |
137 | Urinary urgency (HP:0000012) | 1.76816687 |
138 | Turricephaly (HP:0000262) | 1.76259103 |
139 | Impaired vibratory sensation (HP:0002495) | 1.75281382 |
140 | Carpal synostosis (HP:0009702) | 1.75121459 |
141 | Insidious onset (HP:0003587) | 1.74209227 |
142 | Termporal pattern (HP:0011008) | 1.74209227 |
143 | Relative macrocephaly (HP:0004482) | 1.73974125 |
144 | Supernumerary nipples (HP:0002558) | 1.73646822 |
145 | Esophageal atresia (HP:0002032) | 1.73521832 |
146 | Abnormality of the foot musculature (HP:0001436) | 1.72572630 |
147 | Hypokalemic alkalosis (HP:0001949) | 1.71892384 |
148 | Severe global developmental delay (HP:0011344) | 1.70965894 |
149 | Aqueductal stenosis (HP:0002410) | 1.70207015 |
150 | Abnormality of the dental pulp (HP:0006479) | 1.68578641 |
151 | Generalized myoclonic seizures (HP:0002123) | 1.68287477 |
152 | Genetic anticipation (HP:0003743) | 1.68235848 |
153 | Alacrima (HP:0000522) | 1.67466437 |
154 | Annular pancreas (HP:0001734) | 1.66351454 |
155 | Congenital malformation of the right heart (HP:0011723) | 1.65123971 |
156 | Clonus (HP:0002169) | 1.65103624 |
157 | Mutism (HP:0002300) | 1.64789438 |
158 | Abnormality of the corticospinal tract (HP:0002492) | 1.64730455 |
159 | Abnormality of ocular smooth pursuit (HP:0000617) | 1.64610963 |
160 | Ankyloglossia (HP:0010296) | 1.64401516 |
161 | Gait ataxia (HP:0002066) | 1.64126571 |
162 | Narrow nasal bridge (HP:0000446) | 1.64097824 |
163 | Focal dystonia (HP:0004373) | 1.63270727 |
164 | Limb ataxia (HP:0002070) | 1.61464972 |
165 | Excessive salivation (HP:0003781) | 1.61212948 |
166 | Drooling (HP:0002307) | 1.61212948 |
167 | Polygenic inheritance (HP:0010982) | 1.60448726 |
168 | Confusion (HP:0001289) | 1.58920994 |
169 | Athetosis (HP:0002305) | 1.58611045 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EPHA4 | 5.60337750 |
2 | TNIK | 3.88122459 |
3 | LMTK2 | 3.59343587 |
4 | NTRK3 | 3.29706606 |
5 | NTRK2 | 3.13641482 |
6 | PRKD3 | 3.05206460 |
7 | PHKG1 | 2.89366006 |
8 | PHKG2 | 2.89366006 |
9 | MAP3K9 | 2.40750229 |
10 | TYRO3 | 2.36949137 |
11 | ERBB4 | 2.18045027 |
12 | MINK1 | 2.08743549 |
13 | MARK1 | 2.05037440 |
14 | PAK6 | 1.92604988 |
15 | MAP3K4 | 1.84543122 |
16 | NTRK1 | 1.78063822 |
17 | MAPK13 | 1.63955709 |
18 | DAPK2 | 1.62485280 |
19 | KSR2 | 1.58247215 |
20 | CASK | 1.55240834 |
21 | CAMKK1 | 1.54450578 |
22 | ERBB2 | 1.51985176 |
23 | PRPF4B | 1.46535306 |
24 | MAPK15 | 1.40108391 |
25 | CDK5 | 1.37929851 |
26 | MUSK | 1.33263804 |
27 | MAP2K7 | 1.32180355 |
28 | FES | 1.31655981 |
29 | MAP3K13 | 1.27503088 |
30 | SGK223 | 1.24757479 |
31 | SGK494 | 1.24757479 |
32 | TRIB3 | 1.20484272 |
33 | PNCK | 1.16753456 |
34 | STK38 | 1.15240009 |
35 | SIK1 | 1.13402164 |
36 | CAMK2D | 1.10587634 |
37 | PRKCG | 1.10219801 |
38 | SGK2 | 1.09578933 |
39 | KSR1 | 1.08121557 |
40 | SGK3 | 1.01328175 |
41 | PRKCH | 1.00751683 |
42 | PINK1 | 0.98753384 |
43 | UHMK1 | 0.96522263 |
44 | FGR | 0.95355548 |
45 | MAP2K4 | 0.91995485 |
46 | FGFR4 | 0.88686009 |
47 | RIPK4 | 0.87919199 |
48 | PBK | 0.87800285 |
49 | CSNK1G3 | 0.85355556 |
50 | CDK15 | 0.82810922 |
51 | FGFR2 | 0.81715794 |
52 | GRK5 | 0.81133920 |
53 | CDK18 | 0.79330194 |
54 | BMX | 0.78931739 |
55 | CSNK1A1L | 0.78496203 |
56 | CDK3 | 0.77676917 |
57 | PAK3 | 0.77417103 |
58 | MAPKAPK5 | 0.75685575 |
59 | NEK6 | 0.75204293 |
60 | ICK | 0.74432481 |
61 | PDGFRA | 0.73006694 |
62 | CAMK2A | 0.72960787 |
63 | CDK14 | 0.72799707 |
64 | MAP3K2 | 0.72297496 |
65 | CDK11A | 0.72111371 |
66 | CAMKK2 | 0.71407008 |
67 | ROCK1 | 0.71400254 |
68 | CDC42BPA | 0.70923917 |
69 | DYRK1A | 0.70767400 |
70 | RET | 0.69289384 |
71 | CSNK1G1 | 0.69244820 |
72 | RIPK1 | 0.68241534 |
73 | DDR2 | 0.67260914 |
74 | DYRK2 | 0.66320006 |
75 | OXSR1 | 0.66185353 |
76 | ALK | 0.64947828 |
77 | MAPK12 | 0.64832540 |
78 | ROCK2 | 0.64574387 |
79 | SIK2 | 0.64272067 |
80 | PRKD1 | 0.63507489 |
81 | MAPK11 | 0.62606127 |
82 | TNK2 | 0.62583472 |
83 | IRAK2 | 0.60127735 |
84 | PTK2 | 0.59134787 |
85 | SGK1 | 0.58199414 |
86 | CAMK1 | 0.57441077 |
87 | CAMK1G | 0.56763775 |
88 | PLK2 | 0.55942868 |
89 | RPS6KA3 | 0.54092473 |
90 | TAOK1 | 0.53639340 |
91 | DMPK | 0.53163607 |
92 | LRRK2 | 0.51662561 |
93 | PRKCE | 0.50457797 |
94 | STK11 | 0.50265382 |
95 | DAPK1 | 0.49847054 |
96 | MET | 0.49708537 |
97 | EPHB1 | 0.49404963 |
98 | MARK2 | 0.49345941 |
99 | ARAF | 0.48663212 |
100 | RAF1 | 0.48150273 |
101 | STK39 | 0.47498471 |
102 | FYN | 0.47316822 |
103 | JAK2 | 0.47137426 |
104 | FGFR3 | 0.47065289 |
105 | CSNK1G2 | 0.46344179 |
106 | ADRBK1 | 0.46142300 |
107 | WNK1 | 0.45866421 |
108 | TSSK6 | 0.44415523 |
109 | CDK19 | 0.44392887 |
110 | PDPK1 | 0.44121750 |
111 | PRKCZ | 0.43455687 |
112 | PRKD2 | 0.42381899 |
113 | MAP3K7 | 0.42276203 |
114 | MAPK10 | 0.41721887 |
115 | PDK1 | 0.40616210 |
116 | CSNK1D | 0.40006105 |
117 | PDGFRB | 0.39103163 |
118 | CAMK2B | 0.38932345 |
119 | CAMK2G | 0.38368262 |
120 | PKN1 | 0.37876002 |
121 | PTK2B | 0.37581523 |
122 | MAPK7 | 0.37144102 |
123 | SRC | 0.36380986 |
124 | PRKDC | 0.36278973 |
125 | STK38L | 0.35841554 |
126 | EPHA3 | 0.32174394 |
127 | PIK3CA | 0.31294723 |
128 | WEE1 | 0.30733778 |
129 | TIE1 | 0.29482320 |
130 | PRKG1 | 0.27521741 |
131 | BRSK1 | 0.27437763 |
132 | PAK2 | 0.25624118 |
133 | CSNK1A1 | 0.24735875 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nitrogen metabolism_Homo sapiens_hsa00910 | 4.18929857 |
2 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 3.11869550 |
3 | Nicotine addiction_Homo sapiens_hsa05033 | 2.93232961 |
4 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.54847457 |
5 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 2.48848051 |
6 | GABAergic synapse_Homo sapiens_hsa04727 | 2.48040741 |
7 | Notch signaling pathway_Homo sapiens_hsa04330 | 2.31552891 |
8 | Olfactory transduction_Homo sapiens_hsa04740 | 2.20652426 |
9 | Circadian entrainment_Homo sapiens_hsa04713 | 2.19475398 |
10 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.09201808 |
11 | Salivary secretion_Homo sapiens_hsa04970 | 2.06372408 |
12 | Morphine addiction_Homo sapiens_hsa05032 | 2.00037705 |
13 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.97199742 |
14 | Long-term potentiation_Homo sapiens_hsa04720 | 1.93566689 |
15 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.86060841 |
16 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.83262652 |
17 | Insulin secretion_Homo sapiens_hsa04911 | 1.81167736 |
18 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.71650594 |
19 | Cocaine addiction_Homo sapiens_hsa05030 | 1.59654201 |
20 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.51488438 |
21 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.47432339 |
22 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.42911751 |
23 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.42761433 |
24 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.40875023 |
25 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.37313888 |
26 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.36991649 |
27 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.36949623 |
28 | Long-term depression_Homo sapiens_hsa04730 | 1.29564183 |
29 | Renin secretion_Homo sapiens_hsa04924 | 1.29346281 |
30 | Taste transduction_Homo sapiens_hsa04742 | 1.21253044 |
31 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.20940820 |
32 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.18077451 |
33 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.15611531 |
34 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.15254399 |
35 | Gap junction_Homo sapiens_hsa04540 | 1.14460882 |
36 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 1.11504338 |
37 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.11340527 |
38 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.10543216 |
39 | Axon guidance_Homo sapiens_hsa04360 | 1.09071813 |
40 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.07859548 |
41 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.04706912 |
42 | Bile secretion_Homo sapiens_hsa04976 | 1.02116697 |
43 | Histidine metabolism_Homo sapiens_hsa00340 | 1.01983877 |
44 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.00203464 |
45 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.00191069 |
46 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.97601618 |
47 | Melanogenesis_Homo sapiens_hsa04916 | 0.97260062 |
48 | Glioma_Homo sapiens_hsa05214 | 0.95903526 |
49 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.93801381 |
50 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.93191900 |
51 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.89540939 |
52 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.88518603 |
53 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.87991717 |
54 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.85712891 |
55 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.84942011 |
56 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.82910815 |
57 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.82321653 |
58 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.81906673 |
59 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.79623118 |
60 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.78214173 |
61 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.77081100 |
62 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.76565438 |
63 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.75026671 |
64 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.74013268 |
65 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.73398570 |
66 | Circadian rhythm_Homo sapiens_hsa04710 | 0.72944717 |
67 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.71537242 |
68 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.71127362 |
69 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.70996799 |
70 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.69322141 |
71 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.69271056 |
72 | Melanoma_Homo sapiens_hsa05218 | 0.67854679 |
73 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.67698656 |
74 | Colorectal cancer_Homo sapiens_hsa05210 | 0.65878006 |
75 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.64449312 |
76 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.63984108 |
77 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.63982715 |
78 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.63125397 |
79 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.62294488 |
80 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.62197774 |
81 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.62123274 |
82 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.60708743 |
83 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.60456394 |
84 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.58954918 |
85 | Adherens junction_Homo sapiens_hsa04520 | 0.57868282 |
86 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.57763970 |
87 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.57495837 |
88 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.56835352 |
89 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.56616862 |
90 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.55971960 |
91 | Sulfur relay system_Homo sapiens_hsa04122 | 0.55337042 |
92 | Mineral absorption_Homo sapiens_hsa04978 | 0.54763678 |
93 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.53869795 |
94 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.52181032 |
95 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.49453107 |
96 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.49309514 |
97 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.48325117 |
98 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.48116761 |
99 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.47955853 |
100 | Prion diseases_Homo sapiens_hsa05020 | 0.47751874 |
101 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.47683801 |
102 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.46895381 |
103 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.46499012 |
104 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.46373288 |
105 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.45626500 |
106 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.45282667 |
107 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.44518185 |
108 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.44295566 |
109 | Lysine degradation_Homo sapiens_hsa00310 | 0.43533594 |
110 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.41755260 |
111 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.41372202 |
112 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.40813561 |
113 | Other glycan degradation_Homo sapiens_hsa00511 | 0.39603936 |
114 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.39416453 |
115 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.38853497 |
116 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.38230230 |
117 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.38211714 |
118 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.37138805 |
119 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.35265043 |
120 | Endocytosis_Homo sapiens_hsa04144 | 0.34907720 |
121 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.34750964 |
122 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.32422117 |
123 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.31717420 |
124 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.30901575 |
125 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.30724674 |
126 | Endometrial cancer_Homo sapiens_hsa05213 | 0.30310642 |