BCAP29

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)5.53139542
2ribosomal small subunit assembly (GO:0000028)4.32867943
3negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)4.21135674
4positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)4.04808802
5tRNA methylation (GO:0030488)3.99337151
6antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.85731611
7antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.85731611
8fusion of sperm to egg plasma membrane (GO:0007342)3.85703861
9antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.84591843
10telomere maintenance via semi-conservative replication (GO:0032201)3.81092410
11regulation of integrin-mediated signaling pathway (GO:2001044)3.74791349
12regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.65967732
13cilium or flagellum-dependent cell motility (GO:0001539)3.65057801
14regulation of cell communication by electrical coupling (GO:0010649)3.63254559
15IMP metabolic process (GO:0046040)3.57936638
16negative regulation of protein localization to cell surface (GO:2000009)3.52288949
17antigen processing and presentation via MHC class Ib (GO:0002475)3.51721288
18sperm-egg recognition (GO:0035036)3.49349598
19DNA strand elongation involved in DNA replication (GO:0006271)3.47133018
20binding of sperm to zona pellucida (GO:0007339)3.46244801
21defense response to protozoan (GO:0042832)3.45399710
22telomere maintenance via recombination (GO:0000722)3.45118694
23antigen processing and presentation of endogenous antigen (GO:0019883)3.42289280
24response to interferon-beta (GO:0035456)3.36872952
25regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO3.36132396
26acrosome assembly (GO:0001675)3.31454326
27DNA strand elongation (GO:0022616)3.30061241
28axonemal dynein complex assembly (GO:0070286)3.29374977
29regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)3.27343418
30monoubiquitinated protein deubiquitination (GO:0035520)3.26510182
31DNA replication initiation (GO:0006270)3.25652754
32cell-cell recognition (GO:0009988)3.20869012
33deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.20586490
34Arp2/3 complex-mediated actin nucleation (GO:0034314)3.19967424
35cellular potassium ion homeostasis (GO:0030007)3.18529776
36response to protozoan (GO:0001562)3.18087137
37detection of calcium ion (GO:0005513)3.17422626
38positive regulation of gamma-delta T cell activation (GO:0046645)3.15506947
39pseudouridine synthesis (GO:0001522)3.13144182
40polyketide metabolic process (GO:0030638)3.12524588
41doxorubicin metabolic process (GO:0044598)3.12524588
42daunorubicin metabolic process (GO:0044597)3.12524588
43regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)3.11566846
44synapsis (GO:0007129)3.11355008
45maturation of 5.8S rRNA (GO:0000460)3.10426255
46DNA methylation involved in gamete generation (GO:0043046)3.08215252
47regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)3.07429010
48purine-containing compound salvage (GO:0043101)3.05836049
49negative regulation of calcium ion transmembrane transporter activity (GO:1901020)3.02018651
50negative regulation of calcium ion transmembrane transport (GO:1903170)3.02018651
51positive regulation of B cell differentiation (GO:0045579)3.01023636
52plasma membrane fusion (GO:0045026)2.99115456
53cell wall macromolecule metabolic process (GO:0044036)2.98845899
54cell wall macromolecule catabolic process (GO:0016998)2.98845899
55piRNA metabolic process (GO:0034587)2.96179979
56lipid particle organization (GO:0034389)2.93697320
57motile cilium assembly (GO:0044458)2.92051746
58definitive hemopoiesis (GO:0060216)2.88975366
59regulation of necroptotic process (GO:0060544)2.88700485
60necroptotic process (GO:0070266)2.88077701
61antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.87815891
62mitotic recombination (GO:0006312)2.87438168
63proteasome assembly (GO:0043248)2.86584225
64cell adhesion mediated by integrin (GO:0033627)2.85751924
65mast cell activation (GO:0045576)2.85542173
66positive regulation of mitochondrial calcium ion concentration (GO:0051561)2.85327735
67sperm motility (GO:0030317)2.83795335
68purine nucleobase biosynthetic process (GO:0009113)2.83141279
69negative regulation of necroptotic process (GO:0060546)2.80701851
70GTP biosynthetic process (GO:0006183)2.79752012
71cullin deneddylation (GO:0010388)2.79581609
72glycerol ether metabolic process (GO:0006662)2.78728234
73membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.78484804
74nucleobase biosynthetic process (GO:0046112)2.76794821
75multicellular organism reproduction (GO:0032504)2.75988676
76RNA methylation (GO:0001510)2.75415143
77regulation of meiosis I (GO:0060631)2.75331333
78antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.74796868
79cellular response to interferon-beta (GO:0035458)2.74491447
80heart process (GO:0003015)2.73338900
81heart contraction (GO:0060047)2.73338900
82acrosome reaction (GO:0007340)2.72888758
83tonic smooth muscle contraction (GO:0014820)2.70171486
84vascular smooth muscle contraction (GO:0014829)2.69607086
85negative regulation of appetite (GO:0032099)2.69540966
86negative regulation of response to food (GO:0032096)2.69540966
87IMP biosynthetic process (GO:0006188)2.69467340
88synaptic vesicle maturation (GO:0016188)2.68413294
89telomere maintenance via telomere lengthening (GO:0010833)2.66190305
90respiratory chain complex IV assembly (GO:0008535)2.66124423
91guanosine-containing compound biosynthetic process (GO:1901070)2.65613712
92DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.64247858
93exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.63554283
94metallo-sulfur cluster assembly (GO:0031163)2.63407181
95iron-sulfur cluster assembly (GO:0016226)2.63407181
96platelet dense granule organization (GO:0060155)2.63377912
97CENP-A containing nucleosome assembly (GO:0034080)2.63306980
98artery smooth muscle contraction (GO:0014824)2.61944865
99signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.61512309
100intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.61512309
101regulation of cardiac muscle cell contraction (GO:0086004)2.60800917
102response to gravity (GO:0009629)2.60701484
103formation of translation preinitiation complex (GO:0001731)2.60220320
104maturation of SSU-rRNA (GO:0030490)2.59710049
105regulation of actin filament-based movement (GO:1903115)2.59214423
106negative regulation of cation channel activity (GO:2001258)2.58777806
107nucleotide-excision repair, DNA gap filling (GO:0006297)2.58569274
108ether metabolic process (GO:0018904)2.57200739
109signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.56930699
110signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.56930699
111signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.56930699
112regulation of cilium movement (GO:0003352)2.56080447
113negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.55794228
114CTP biosynthetic process (GO:0006241)2.54718277
115CTP metabolic process (GO:0046036)2.54718277
116chromatin remodeling at centromere (GO:0031055)2.54691874
117positive regulation of meiosis (GO:0045836)2.54503173
118regulation of relaxation of muscle (GO:1901077)2.54462290
119nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.54236628
120deoxyribose phosphate biosynthetic process (GO:0046385)2.54116186
1212-deoxyribonucleotide biosynthetic process (GO:0009265)2.54116186
122mitochondrial respiratory chain complex I assembly (GO:0032981)2.53451687
123NADH dehydrogenase complex assembly (GO:0010257)2.53451687
124mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.53451687
125response to redox state (GO:0051775)2.53372698
126RNA capping (GO:0036260)2.53097677
1277-methylguanosine RNA capping (GO:0009452)2.53097677
128protein complex biogenesis (GO:0070271)2.52649542
129positive regulation of mitochondrial fission (GO:0090141)2.52579169
130cytochrome complex assembly (GO:0017004)2.52054746
131epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.51534580
132L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.51527230
133positive regulation of protein autophosphorylation (GO:0031954)2.50746273
134ether lipid metabolic process (GO:0046485)2.50178047
1357-methylguanosine mRNA capping (GO:0006370)2.50109641
136rRNA processing (GO:0006364)2.50028968
137pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.49599637
138pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.47973342
139positive regulation of cardiac muscle hypertrophy (GO:0010613)2.46550728
140positive regulation of muscle hypertrophy (GO:0014742)2.46550728
141signal peptide processing (GO:0006465)2.45459894
142water-soluble vitamin biosynthetic process (GO:0042364)2.44441876
143negative regulation of meiosis (GO:0045835)2.43645075
144protein deneddylation (GO:0000338)2.40026396
145mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.39325860
146response to lead ion (GO:0010288)2.38957987
147regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)2.37726931
148regulation of acyl-CoA biosynthetic process (GO:0050812)2.37613095
149lipopolysaccharide biosynthetic process (GO:0009103)2.36427643
150sodium ion export (GO:0071436)2.34242002
151cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.31365098
152glutamate secretion (GO:0014047)2.30820491
153striatum development (GO:0021756)2.30617340
154C4-dicarboxylate transport (GO:0015740)2.30432449
155regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.29815606
156regulation of lipoprotein metabolic process (GO:0050746)2.29576106
157positive regulation of actin filament depolymerization (GO:0030836)2.28454994
158regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.27548448
159positive regulation of meiotic cell cycle (GO:0051446)2.27151868
160endothelium development (GO:0003158)2.26336087
161protein heterotetramerization (GO:0051290)2.25615484
162Golgi to plasma membrane protein transport (GO:0043001)2.25597553
163regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)2.25057677
164tricarboxylic acid cycle (GO:0006099)2.24859874
165retina vasculature morphogenesis in camera-type eye (GO:0061299)2.22151905
166regulation of sulfur metabolic process (GO:0042762)2.21514797
167regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022352.21401924
168male meiosis I (GO:0007141)2.20065743
169peroxisome fission (GO:0016559)2.18658881
170resolution of meiotic recombination intermediates (GO:0000712)2.17360048
171membrane assembly (GO:0071709)2.14403466
172positive regulation of potassium ion transport (GO:0043268)2.14034275
173cellular response to leptin stimulus (GO:0044320)2.13891784
174regulation of protein localization to cell surface (GO:2000008)2.11076919
175fatty acid elongation (GO:0030497)2.08308186
176relaxation of muscle (GO:0090075)2.08280190
177potassium ion homeostasis (GO:0055075)2.08195339
178brain morphogenesis (GO:0048854)2.08158171
179mitochondrial calcium ion homeostasis (GO:0051560)2.07501021
180regulation of cofactor metabolic process (GO:0051193)2.07337311
181regulation of coenzyme metabolic process (GO:0051196)2.07337311
182regulation of response to food (GO:0032095)2.07132301
183chromosome organization involved in meiosis (GO:0070192)2.06991483
184membrane budding (GO:0006900)2.05676164
185positive regulation of calcium ion transmembrane transporter activity (GO:1901021)2.05192207
186ADP metabolic process (GO:0046031)2.04617165
187synaptic vesicle docking involved in exocytosis (GO:0016081)2.03477381
188ventricular cardiac muscle cell development (GO:0055015)2.03131217
189neurotransmitter uptake (GO:0001504)2.02781309
190regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.02536404
191regulation of ER to Golgi vesicle-mediated transport (GO:0060628)2.02283044
192regulation of dendritic spine development (GO:0060998)2.00511353
193negative regulation of calcium ion-dependent exocytosis (GO:0045955)1.99665622
194synaptic vesicle exocytosis (GO:0016079)1.99636871

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.51618893
2EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.32558235
3MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse3.18000322
4IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.05302998
5NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.02890733
6POU3F2_20337985_ChIP-ChIP_501MEL_Human3.01371143
7EST1_17652178_ChIP-ChIP_JURKAT_Human2.85582358
8KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.85158242
9ELF1_17652178_ChIP-ChIP_JURKAT_Human2.81031135
10SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.76822852
11SCL_19346495_ChIP-Seq_HPC-7_Human2.74209975
12MYC_18555785_ChIP-Seq_MESCs_Mouse2.71364563
13GABP_17652178_ChIP-ChIP_JURKAT_Human2.67571710
14ZFP57_27257070_Chip-Seq_ESCs_Mouse2.66909568
15JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.59660635
16HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.55782515
17CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.55758774
18IRF8_22096565_ChIP-ChIP_GC-B_Human2.55413552
19GBX2_23144817_ChIP-Seq_PC3_Human2.52442806
20FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.46757177
21VDR_23849224_ChIP-Seq_CD4+_Human2.42090276
22SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.41423162
23MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.39712751
24CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.39502410
25E2F4_17652178_ChIP-ChIP_JURKAT_Human2.38149551
26WT1_19549856_ChIP-ChIP_CCG9911_Human2.35466464
27ETS1_20019798_ChIP-Seq_JURKAT_Human2.33616653
28TAF15_26573619_Chip-Seq_HEK293_Human2.31549277
29TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.28987788
30SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse2.27428243
31IRF8_21731497_ChIP-ChIP_J774_Mouse2.24719614
32SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.24066542
33RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.21272521
34* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.17809966
35SMAD_19615063_ChIP-ChIP_OVARY_Human2.16292357
36HOXB4_20404135_ChIP-ChIP_EML_Mouse2.15066073
37HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.11156506
38FOXP3_21729870_ChIP-Seq_TREG_Human2.09634673
39SRF_21415370_ChIP-Seq_HL-1_Mouse2.07985177
40PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.05191581
41IGF1R_20145208_ChIP-Seq_DFB_Human2.01760334
42CDX2_19796622_ChIP-Seq_MESCs_Mouse2.01389319
43FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse2.01298623
44AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human2.01039328
45MYB_21317192_ChIP-Seq_ERMYB_Mouse1.98845681
46ERG_20887958_ChIP-Seq_HPC-7_Mouse1.98008120
47MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.97683857
48LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.96416894
49RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.95445394
50NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.94912409
51NRF2_20460467_ChIP-Seq_MEFs_Mouse1.94912409
52CREB1_15753290_ChIP-ChIP_HEK293T_Human1.94353761
53SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.90639826
54P300_19829295_ChIP-Seq_ESCs_Human1.89691597
55EP300_21415370_ChIP-Seq_HL-1_Mouse1.87461887
56* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.87389225
57OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.86708791
58VDR_22108803_ChIP-Seq_LS180_Human1.85994401
59CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.82017405
60SPI1_23547873_ChIP-Seq_NB4_Human1.80803570
61CJUN_26792858_Chip-Seq_BT549_Human1.80613129
62FUS_26573619_Chip-Seq_HEK293_Human1.80032162
63SMAD4_21799915_ChIP-Seq_A2780_Human1.77448904
64STAT4_19710469_ChIP-ChIP_TH1__Mouse1.76830702
65ELK1_19687146_ChIP-ChIP_HELA_Human1.76236163
66RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.74504526
67EWS_26573619_Chip-Seq_HEK293_Human1.71584431
68PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.71104934
69TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.69763029
70TRIM28_21343339_ChIP-Seq_HEK293_Human1.68234166
71PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.67591249
72* ER_23166858_ChIP-Seq_MCF-7_Human1.64800562
73ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.63821916
74CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.63820717
75SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.63369649
76TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.62519345
77THAP11_20581084_ChIP-Seq_MESCs_Mouse1.62405297
78EZH2_27294783_Chip-Seq_NPCs_Mouse1.61165985
79GABP_19822575_ChIP-Seq_HepG2_Human1.60996164
80XRN2_22483619_ChIP-Seq_HELA_Human1.60847992
81PIAS1_25552417_ChIP-Seq_VCAP_Human1.60624324
82BRD4_25478319_ChIP-Seq_HGPS_Human1.60444379
83MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.58522581
84IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.58297020
85MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.55776780
86NANOG_18555785_Chip-Seq_ESCs_Mouse1.53633600
87GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.52729036
88AR_21909140_ChIP-Seq_LNCAP_Human1.51509310
89MYB_26560356_Chip-Seq_TH2_Human1.51013366
90GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.48380626
91LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.48157840
92DCP1A_22483619_ChIP-Seq_HELA_Human1.47778735
93PCGF2_27294783_Chip-Seq_ESCs_Mouse1.44817501
94CTBP2_25329375_ChIP-Seq_LNCAP_Human1.44062667
95NOTCH1_21737748_ChIP-Seq_TLL_Human1.43997944
96* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.43106275
97FOXM1_26456572_ChIP-Seq_MCF-7_Human1.40202736
98E2F1_18555785_ChIP-Seq_MESCs_Mouse1.39364919
99GATA2_21666600_ChIP-Seq_HMVEC_Human1.38455238
100EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.38372523
101SALL4_18804426_ChIP-ChIP_XEN_Mouse1.38072702
102E2F1_18555785_Chip-Seq_ESCs_Mouse1.38034499
103SUZ12_27294783_Chip-Seq_NPCs_Mouse1.36173349
104MYC_19079543_ChIP-ChIP_MESCs_Mouse1.36018587
105P53_22387025_ChIP-Seq_ESCs_Mouse1.35577159
106MYB_26560356_Chip-Seq_TH1_Human1.35400299
107PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.34603237
108SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.34214473
109TTF2_22483619_ChIP-Seq_HELA_Human1.33956102
110TOP2B_26459242_ChIP-Seq_MCF-7_Human1.32157936
111STAT3_23295773_ChIP-Seq_U87_Human1.30795059
112RUNX1_22412390_ChIP-Seq_EML_Mouse1.30368669
113SUZ12_18555785_Chip-Seq_ESCs_Mouse1.28307024
114CMYC_18555785_Chip-Seq_ESCs_Mouse1.27856656
115UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.27309965
116GATA1_22383799_ChIP-Seq_G1ME_Mouse1.26703359
117SOX2_18555785_Chip-Seq_ESCs_Mouse1.26067753
118STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.25320824
119* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.25262772
120SMAD3_21741376_ChIP-Seq_EPCs_Human1.25234493
121AR_25329375_ChIP-Seq_VCAP_Human1.24254424
122TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.24225329
123PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.24211138
124TP53_18474530_ChIP-ChIP_U2OS_Human1.23955560
125STAT3_18555785_Chip-Seq_ESCs_Mouse1.23500809
126YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.22893137
127NELFA_20434984_ChIP-Seq_ESCs_Mouse1.22289510
128ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.22269690
129CDX2_22108803_ChIP-Seq_LS180_Human1.20733507
130JUN_21703547_ChIP-Seq_K562_Human1.20509779
131SALL1_21062744_ChIP-ChIP_HESCs_Human1.19632826
132CRX_20693478_ChIP-Seq_RETINA_Mouse1.19502904
133ZFX_18555785_ChIP-Seq_MESCs_Mouse1.19121462
134CIITA_25753668_ChIP-Seq_RAJI_Human1.19107153
135PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.19025909
136TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.17210051
137* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.16529500
138TCF4_23295773_ChIP-Seq_U87_Human1.16488744
139YY1_21170310_ChIP-Seq_MESCs_Mouse1.15055089
140ZNF217_24962896_ChIP-Seq_MCF-7_Human1.14699298
141EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.13539498
142E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.12158341
143GATA2_22383799_ChIP-Seq_G1ME_Mouse1.11911975
144NR3C1_21868756_ChIP-Seq_MCF10A_Human1.11479313
145ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.11022000
146IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.10937097
147CBP_20019798_ChIP-Seq_JUKART_Human1.10937097
148* MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.09609572
149NMYC_18555785_Chip-Seq_ESCs_Mouse1.08620661
150NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.08533312
151NFE2_27457419_Chip-Seq_LIVER_Mouse1.08117984
152IRF8_27001747_Chip-Seq_BMDM_Mouse1.08071565
153P300_18555785_Chip-Seq_ESCs_Mouse1.07792384
154GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.07328592
155MYC_18940864_ChIP-ChIP_HL60_Human1.07066422
156CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.06714751
157NR3C1_23031785_ChIP-Seq_PC12_Mouse1.06680765
158E2F1_21310950_ChIP-Seq_MCF-7_Human1.04796223
159TAL1_26923725_Chip-Seq_HPCs_Mouse1.04510597
160HTT_18923047_ChIP-ChIP_STHdh_Human1.04428723
161BP1_19119308_ChIP-ChIP_Hs578T_Human1.04245215
162NANOG_19829295_ChIP-Seq_ESCs_Human1.04148183
163SOX2_19829295_ChIP-Seq_ESCs_Human1.04148183
164CTBP1_25329375_ChIP-Seq_LNCAP_Human1.03770590
165SOX9_26525672_Chip-Seq_HEART_Mouse1.02766332
166OCT4_18555785_Chip-Seq_ESCs_Mouse1.02634566
167BCAT_22108803_ChIP-Seq_LS180_Human1.02478223
168TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.01954606
169FLI1_27457419_Chip-Seq_LIVER_Mouse1.01845290
170CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01491134
171MYC_22102868_ChIP-Seq_BL_Human1.01323867
172E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.00784004
173* MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.00671504
174* KLF5_20875108_ChIP-Seq_MESCs_Mouse1.00353048
175FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.98863780
176POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.98154235
177GATA3_26560356_Chip-Seq_TH2_Human0.98069709
178VDR_21846776_ChIP-Seq_THP-1_Human0.97277376
179KDM5A_27292631_Chip-Seq_BREAST_Human0.96886256
180GATA3_27048872_Chip-Seq_THYMUS_Human0.96624413
181PU.1_20513432_ChIP-Seq_Bcells_Mouse0.95539606
182GATA1_22025678_ChIP-Seq_K562_Human0.93989875
183FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.93756415
184CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.92209167
185SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse0.91202398
186STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.91193471
187ETS1_22383799_ChIP-Seq_G1ME_Mouse0.89940677
188* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.88289430
189FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.87608173
190CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.87245560
191CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.87092643

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006292_abnormal_olfactory_placode3.46285829
2MP0001835_abnormal_antigen_presentation3.45497400
3MP0002396_abnormal_hematopoietic_system3.39118112
4MP0004510_myositis3.35841722
5MP0003950_abnormal_plasma_membrane3.27477723
6MP0003724_increased_susceptibility_to3.17832349
7MP0004215_abnormal_myocardial_fiber3.03129490
8MP0005671_abnormal_response_to2.98415583
9MP0005410_abnormal_fertilization2.94703381
10MP0008438_abnormal_cutaneous_collagen2.85303731
11MP0009785_altered_susceptibility_to2.79142763
12MP0009780_abnormal_chondrocyte_physiolo2.75717168
13MP0009697_abnormal_copulation2.73371379
14MP0010368_abnormal_lymphatic_system2.70736034
15MP0003880_abnormal_central_pattern2.49344375
16MP0004808_abnormal_hematopoietic_stem2.40454148
17MP0004272_abnormal_basement_membrane2.36777616
18MP0005174_abnormal_tail_pigmentation2.28356402
19MP0003763_abnormal_thymus_physiology2.27590661
20MP0005075_abnormal_melanosome_morpholog2.26092532
21MP0008877_abnormal_DNA_methylation2.25148129
22MP0005464_abnormal_platelet_physiology2.14795707
23MP0002166_altered_tumor_susceptibility2.14219026
24MP0010094_abnormal_chromosome_stability2.11135500
25MP0000569_abnormal_digit_pigmentation2.09277496
26MP0003172_abnormal_lysosome_physiology2.06449795
27MP0001984_abnormal_olfaction2.05729992
28MP0005275_abnormal_skin_tensile1.98414084
29MP0001545_abnormal_hematopoietic_system1.96952476
30MP0005397_hematopoietic_system_phenotyp1.96952476
31MP0004147_increased_porphyrin_level1.96658737
32MP0000015_abnormal_ear_pigmentation1.92816121
33MP0002398_abnormal_bone_marrow1.89793513
34MP0005171_absent_coat_pigmentation1.89502550
35MP0008775_abnormal_heart_ventricle1.89239657
36MP0005025_abnormal_response_to1.86751695
37MP0001879_abnormal_lymphatic_vessel1.86516105
38MP0005000_abnormal_immune_tolerance1.83722702
39MP0001800_abnormal_humoral_immune1.83461985
40MP0002148_abnormal_hypersensitivity_rea1.79815905
41MP0002420_abnormal_adaptive_immunity1.75362751
42MP0000751_myopathy1.73845739
43MP0002972_abnormal_cardiac_muscle1.72522400
44MP0001819_abnormal_immune_cell1.72455192
45MP0002837_dystrophic_cardiac_calcinosis1.70907815
46MP0008058_abnormal_DNA_repair1.70374062
47MP0002723_abnormal_immune_serum1.69531547
48MP0008057_abnormal_DNA_replication1.67829405
49MP0006054_spinal_hemorrhage1.66873269
50MP0000689_abnormal_spleen_morphology1.65982367
51MP0002452_abnormal_antigen_presenting1.65948611
52MP0005330_cardiomyopathy1.65105558
53MP0002006_tumorigenesis1.64346865
54MP0006036_abnormal_mitochondrial_physio1.58216669
55MP0000716_abnormal_immune_system1.56970546
56MP0002419_abnormal_innate_immunity1.56725476
57MP0004484_altered_response_of1.51909412
58MP0003656_abnormal_erythrocyte_physiolo1.50995833
59MP0002722_abnormal_immune_system1.50115235
60MP0000749_muscle_degeneration1.49709871
61MP0001929_abnormal_gametogenesis1.48928521
62MP0004957_abnormal_blastocyst_morpholog1.48869579
63MP0004859_abnormal_synaptic_plasticity1.48513783
64MP0000685_abnormal_immune_system1.47846358
65MP0002095_abnormal_skin_pigmentation1.44695768
66MP0002429_abnormal_blood_cell1.44268649
67MP0000465_gastrointestinal_hemorrhage1.43739671
68MP0003693_abnormal_embryo_hatching1.43315623
69MP0001853_heart_inflammation1.40848519
70MP0005620_abnormal_muscle_contractility1.40541845
71MP0003866_abnormal_defecation1.39296980
72MP0001986_abnormal_taste_sensitivity1.39295394
73MP0009333_abnormal_splenocyte_physiolog1.39177035
74MP0003011_delayed_dark_adaptation1.38908685
75MP0006138_congestive_heart_failure1.38087301
76MP0003436_decreased_susceptibility_to1.37865572
77MP0005167_abnormal_blood-brain_barrier1.36853860
78MP0008007_abnormal_cellular_replicative1.35893269
79MP0003698_abnormal_male_reproductive1.35787565
80MP0005503_abnormal_tendon_morphology1.34868728
81MP0009046_muscle_twitch1.32520784
82MP0000372_irregular_coat_pigmentation1.31396958
83MP0005058_abnormal_lysosome_morphology1.30130945
84MP0003123_paternal_imprinting1.29703855
85MP0000490_abnormal_crypts_of1.29493411
86MP0004085_abnormal_heartbeat1.28255379
87MP0005187_abnormal_penis_morphology1.27359014
88MP0002295_abnormal_pulmonary_circulatio1.25951926
89MP0005165_increased_susceptibility_to1.25777871
90MP0002877_abnormal_melanocyte_morpholog1.24362961
91MP0003077_abnormal_cell_cycle1.20299663
92MP0002405_respiratory_system_inflammati1.20153514
93MP0004885_abnormal_endolymph1.18604731
94MP0000703_abnormal_thymus_morphology1.17239105
95MP0006035_abnormal_mitochondrial_morpho1.17013555
96MP0010678_abnormal_skin_adnexa1.15662998
97MP0002210_abnormal_sex_determination1.13146262
98MP0002272_abnormal_nervous_system1.13134224
99MP0000647_abnormal_sebaceous_gland1.13010889
100MP0001845_abnormal_inflammatory_respons1.11758926
101MP0005385_cardiovascular_system_phenoty1.11511408
102MP0001544_abnormal_cardiovascular_syste1.11511408
103MP0003111_abnormal_nucleus_morphology1.11407941
104MP0005253_abnormal_eye_physiology1.11334715
105MP0000383_abnormal_hair_follicle1.11230827
106MP0000427_abnormal_hair_cycle1.10076639
107MP0000516_abnormal_urinary_system1.08632540
108MP0005367_renal/urinary_system_phenotyp1.08632540
109MP0001873_stomach_inflammation1.08164030
110MP0001299_abnormal_eye_distance/1.07400645
111MP0003279_aneurysm1.06813894
112MP0008469_abnormal_protein_level1.03677154
113MP0006082_CNS_inflammation1.03517352
114MP0000747_muscle_weakness1.00428080
115MP0010155_abnormal_intestine_physiology1.00396592
116MP0010386_abnormal_urinary_bladder0.99404179
117MP0001542_abnormal_bone_strength0.99225483
118MP0003137_abnormal_impulse_conducting0.99002091
119MP0001764_abnormal_homeostasis0.98969758
120MP0001486_abnormal_startle_reflex0.97868781
121MP0002090_abnormal_vision0.97474841
122MP0001905_abnormal_dopamine_level0.97301911
123MP0001145_abnormal_male_reproductive0.96839627
124MP0000013_abnormal_adipose_tissue0.96644767
125MP0001529_abnormal_vocalization0.96067608
126MP0002064_seizures0.95384435
127MP0001501_abnormal_sleep_pattern0.94825911
128MP0005423_abnormal_somatic_nervous0.94561766
129MP0009384_cardiac_valve_regurgitation0.94380088
130MP0004270_analgesia0.94251897
131MP0002269_muscular_atrophy0.93062158
132MP0001177_atelectasis0.91824185
133MP0009745_abnormal_behavioral_response0.91488226
134MP0002019_abnormal_tumor_incidence0.91107887
135MP0003566_abnormal_cell_adhesion0.90510650
136MP0001790_abnormal_immune_system0.90052100
137MP0005387_immune_system_phenotype0.90052100
138MP0000920_abnormal_myelination0.88891764
139MP0002332_abnormal_exercise_endurance0.88835448
140MP0004924_abnormal_behavior0.86930561
141MP0005386_behavior/neurological_phenoty0.86930561
142MP0003186_abnormal_redox_activity0.85904694
143MP0002876_abnormal_thyroid_physiology0.84349872
144MP0002896_abnormal_bone_mineralization0.84112235
145MP0005595_abnormal_vascular_smooth0.83709039
146MP0002736_abnormal_nociception_after0.83488541
147MP0000358_abnormal_cell_content/0.83488456
148MP0003633_abnormal_nervous_system0.83479733
149MP0001919_abnormal_reproductive_system0.83238851
150MP0005551_abnormal_eye_electrophysiolog0.82248570
151MP0000343_altered_response_to0.82130750
152MP0003635_abnormal_synaptic_transmissio0.81002044
153MP0000653_abnormal_sex_gland0.80442482
154MP0004087_abnormal_muscle_fiber0.80047373
155MP0003786_premature_aging0.78744644
156MP0001188_hyperpigmentation0.78742127
157MP0001958_emphysema0.78594026
158MP0003806_abnormal_nucleotide_metabolis0.78533438
159MP0000313_abnormal_cell_death0.77380545
160MP0002735_abnormal_chemical_nociception0.77136605
161MP0003385_abnormal_body_wall0.76451592
162MP0004233_abnormal_muscle_weight0.75948344
163MP0003828_pulmonary_edema0.75862724
164MP0005389_reproductive_system_phenotype0.75635788
165MP0005084_abnormal_gallbladder_morpholo0.74038193
166MP0001968_abnormal_touch/_nociception0.72521358
167MP0004084_abnormal_cardiac_muscle0.71867964
168MP0002108_abnormal_muscle_morphology0.71853318
169MP0002734_abnormal_mechanical_nocicepti0.70937940
170MP0005408_hypopigmentation0.70936244
171MP0002161_abnormal_fertility/fecundity0.70594803
172MP0005646_abnormal_pituitary_gland0.67712682
173MP0002234_abnormal_pharynx_morphology0.67091673
174MP0004036_abnormal_muscle_relaxation0.63803415
175MP0008873_increased_physiological_sensi0.62876731
176MP0005310_abnormal_salivary_gland0.60825695
177MP0002160_abnormal_reproductive_system0.60525915

Predicted human phenotypes

RankGene SetZ-score
1Dynein arm defect of respiratory motile cilia (HP:0012255)4.04456639
2Absent/shortened dynein arms (HP:0200106)4.04456639
3Aplastic anemia (HP:0001915)4.02078477
4Nasal polyposis (HP:0100582)3.78754283
5Abnormal number of erythroid precursors (HP:0012131)3.61752755
6Thrombocytosis (HP:0001894)3.54957950
7IgM deficiency (HP:0002850)3.48945066
8Abnormal respiratory epithelium morphology (HP:0012253)3.48752995
9Abnormal respiratory motile cilium morphology (HP:0005938)3.48752995
10Hepatocellular necrosis (HP:0001404)3.47920415
11Elevated erythrocyte sedimentation rate (HP:0003565)3.47610499
12Chronic otitis media (HP:0000389)3.44106577
13Petechiae (HP:0000967)3.43044726
14Recurrent bronchitis (HP:0002837)3.42954006
15Myositis (HP:0100614)3.42927104
16Recurrent abscess formation (HP:0002722)3.40904859
17Type 2 muscle fiber atrophy (HP:0003554)3.40398705
18Abnormality of cells of the erythroid lineage (HP:0012130)3.33631754
19Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.30629533
20Abnormality of the nasal mucosa (HP:0000433)3.17548314
21Gonadotropin excess (HP:0000837)3.14977220
22Papilledema (HP:0001085)3.10856142
23Bundle branch block (HP:0011710)3.08158140
24Muscle fiber atrophy (HP:0100295)3.07428079
25Recurrent bacterial skin infections (HP:0005406)3.06488272
26Hepatic necrosis (HP:0002605)3.04213076
27Birth length less than 3rd percentile (HP:0003561)2.93148823
28Abnormality of the heme biosynthetic pathway (HP:0010472)2.86024134
29Type I transferrin isoform profile (HP:0003642)2.84879867
30Bronchitis (HP:0012387)2.84288953
31Prolonged bleeding time (HP:0003010)2.77514424
32Abnormal spermatogenesis (HP:0008669)2.71536181
33Mitochondrial inheritance (HP:0001427)2.68374441
34IgG deficiency (HP:0004315)2.67106696
35Progressive macrocephaly (HP:0004481)2.63171682
36Abnormal respiratory motile cilium physiology (HP:0012261)2.63074427
37Hyporeflexia of lower limbs (HP:0002600)2.61286331
38Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.60066803
39Decreased activity of mitochondrial respiratory chain (HP:0008972)2.60066803
40Exercise-induced muscle cramps (HP:0003710)2.53897199
41Reduced antithrombin III activity (HP:0001976)2.53840215
423-Methylglutaconic aciduria (HP:0003535)2.53284474
43Renal cortical cysts (HP:0000803)2.52391050
44Increased CSF lactate (HP:0002490)2.50367462
45Abnormal auditory evoked potentials (HP:0006958)2.50265169
46Metaphyseal dysplasia (HP:0100255)2.50169820
47Atonic seizures (HP:0010819)2.49800125
48Patchy hypopigmentation of hair (HP:0011365)2.49402361
49Abnormality of T cell physiology (HP:0011840)2.41646670
50Abnormal ciliary motility (HP:0012262)2.41479104
51Tetraparesis (HP:0002273)2.38197559
5211 pairs of ribs (HP:0000878)2.37938506
53Neurodegeneration (HP:0002180)2.36174854
54Epistaxis (HP:0000421)2.35942416
55Rhinitis (HP:0012384)2.35235803
56Optic neuritis (HP:0100653)2.35002836
57Retrobulbar optic neuritis (HP:0100654)2.35002836
58Orchitis (HP:0100796)2.34892211
59Fair hair (HP:0002286)2.33855823
60Myelodysplasia (HP:0002863)2.33444709
61Abnormal protein glycosylation (HP:0012346)2.32720186
62Abnormal glycosylation (HP:0012345)2.32720186
63Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.32720186
64Abnormal protein N-linked glycosylation (HP:0012347)2.32720186
65Pancytopenia (HP:0001876)2.31178270
66Chronic sinusitis (HP:0011109)2.30397424
67Premature rupture of membranes (HP:0001788)2.29932147
68Increased serum lactate (HP:0002151)2.27261172
69Deformed sella turcica (HP:0002681)2.26339228
70Nemaline bodies (HP:0003798)2.26308502
71Increased hepatocellular lipid droplets (HP:0006565)2.22040516
72Action tremor (HP:0002345)2.21974870
73Bronchiectasis (HP:0002110)2.21935513
74Encephalitis (HP:0002383)2.20058880
75Vascular tortuosity (HP:0004948)2.18958442
76Increased intramyocellular lipid droplets (HP:0012240)2.18019349
77Exertional dyspnea (HP:0002875)2.17505568
78Acute encephalopathy (HP:0006846)2.17059166
79Hemiparesis (HP:0001269)2.16576200
80Abnormal mitochondria in muscle tissue (HP:0008316)2.15409268
81Impaired platelet aggregation (HP:0003540)2.14967235
82Abnormal platelet function (HP:0011869)2.14967235
83Limb-girdle muscle atrophy (HP:0003797)2.13639326
84Abnormality of T cells (HP:0002843)2.11439140
85B lymphocytopenia (HP:0010976)2.11426982
86Abnormality of B cell number (HP:0010975)2.11426982
87Acute necrotizing encephalopathy (HP:0006965)2.10061910
88Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.09635948
89Purpura (HP:0000979)2.09550723
90Hyperventilation (HP:0002883)2.09189871
91Abnormality of the musculature of the pelvis (HP:0001469)2.09114511
92Abnormality of the hip-girdle musculature (HP:0001445)2.09114511
93Degeneration of anterior horn cells (HP:0002398)2.08566636
94Abnormality of the anterior horn cell (HP:0006802)2.08566636
95Arterial tortuosity (HP:0005116)2.07428122
96Degeneration of the lateral corticospinal tracts (HP:0002314)2.07012715
97Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.07012715
98Pulmonary fibrosis (HP:0002206)2.05029773
99Infertility (HP:0000789)2.05026411
100Breast hypoplasia (HP:0003187)2.04744996
101J-shaped sella turcica (HP:0002680)2.04479174
102Bone marrow hypocellularity (HP:0005528)2.04228695
103Muscle fiber inclusion bodies (HP:0100299)2.03010853
104Glucose intolerance (HP:0000833)2.01996063
105White forelock (HP:0002211)2.01171686
106Focal motor seizures (HP:0011153)2.00043152
107Palpitations (HP:0001962)1.99697155
108Congenital, generalized hypertrichosis (HP:0004540)1.99552451
109Hypergammaglobulinemia (HP:0010702)1.99450484
110Acute myeloid leukemia (HP:0004808)1.98801365
111Abnormality of the calf musculature (HP:0001430)1.97502367
112Sudden death (HP:0001699)1.97487857
113Recurrent sinusitis (HP:0011108)1.97286415
114Thyroid carcinoma (HP:0002890)1.97133030
115Chronic bronchitis (HP:0004469)1.96291374
116Reduced subcutaneous adipose tissue (HP:0003758)1.96256040
117Abnormal atrioventricular conduction (HP:0005150)1.95774916
118Atrial fibrillation (HP:0005110)1.95130063
119Lactic acidosis (HP:0003128)1.95014282
120Neoplasm of the peripheral nervous system (HP:0100007)1.95009284
121Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.94695183
122Nonprogressive disorder (HP:0003680)1.94354651
123Hypoplastic left heart (HP:0004383)1.93840750
124Onycholysis (HP:0001806)1.93821627
125Heart block (HP:0012722)1.93719722
126Oral leukoplakia (HP:0002745)1.93629659
127Generalized hypopigmentation of hair (HP:0011358)1.93493772
128Syncope (HP:0001279)1.92663938
129Medial flaring of the eyebrow (HP:0010747)1.92093343
130Abnormality of the corticospinal tract (HP:0002492)1.92088423
131Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.92023702
132Abnormality of the preputium (HP:0100587)1.91814873
133Spinal rigidity (HP:0003306)1.91636957
134Abnormality of the prostate (HP:0008775)1.91519985
135Abnormality of the lower motor neuron (HP:0002366)1.91253378
136Periodontitis (HP:0000704)1.90160529
137Lipid accumulation in hepatocytes (HP:0006561)1.90151024
138Methylmalonic acidemia (HP:0002912)1.89819554
139Lipoatrophy (HP:0100578)1.89782908
140Meningitis (HP:0001287)1.89191908
141Microglossia (HP:0000171)1.88631605
142Clubbing of toes (HP:0100760)1.88625166
143Erythema (HP:0010783)1.88267595
144Papillary thyroid carcinoma (HP:0002895)1.87468656
145Increased serum pyruvate (HP:0003542)1.87369866
146Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.86162670
147Abnormality of alanine metabolism (HP:0010916)1.86162670
148Hyperalaninemia (HP:0003348)1.86162670
149Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.86097540
150Aplasia/Hypoplasia of the sacrum (HP:0008517)1.85198075
151Respiratory difficulties (HP:0002880)1.84801626
152Abnormality of glycolysis (HP:0004366)1.83799596
153Febrile seizures (HP:0002373)1.83013116
154Follicular hyperkeratosis (HP:0007502)1.82718624
155Gait imbalance (HP:0002141)1.81908343
156Dyschromatopsia (HP:0007641)1.81123565
157Delayed gross motor development (HP:0002194)1.79417864
158Congenital primary aphakia (HP:0007707)1.78868196
159Primary atrial arrhythmia (HP:0001692)1.78605737
160Horizontal nystagmus (HP:0000666)1.76877893
161Hydroureter (HP:0000072)1.75846755
162Supraventricular arrhythmia (HP:0005115)1.74914997
163Cerebral edema (HP:0002181)1.74391510
164Cerebral hypomyelination (HP:0006808)1.74311652
165Supraventricular tachycardia (HP:0004755)1.74049082
166Rimmed vacuoles (HP:0003805)1.73801112
167Neuroendocrine neoplasm (HP:0100634)1.70422112
168Respiratory failure (HP:0002878)1.68559787
169Type 1 muscle fiber predominance (HP:0003803)1.66121205
170Nephrogenic diabetes insipidus (HP:0009806)1.65974581
171Hypoplastic heart (HP:0001961)1.65653981
172Renal Fanconi syndrome (HP:0001994)1.64727467
173Generalized tonic-clonic seizures (HP:0002069)1.64702226
174Conjunctival hamartoma (HP:0100780)1.64466250
175Atrioventricular block (HP:0001678)1.64331322
176Upper limb muscle weakness (HP:0003484)1.63335716
177Absent speech (HP:0001344)1.62141175
178Sensory axonal neuropathy (HP:0003390)1.59889191
179Left ventricular hypertrophy (HP:0001712)1.57399555
180Muscle fiber splitting (HP:0003555)1.57242079
181Neoplasm of the small intestine (HP:0100833)1.55939731
182Myoglobinuria (HP:0002913)1.53251900
183Abnormality of midbrain morphology (HP:0002418)1.52602337
184Molar tooth sign on MRI (HP:0002419)1.52602337
185Ventricular arrhythmia (HP:0004308)1.52362138
186Abnormality of methionine metabolism (HP:0010901)1.51680483
187Hypoplasia of the iris (HP:0007676)1.51656909
188Cardiovascular calcification (HP:0011915)1.48725441

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK164.62907638
2BRSK23.29368733
3CAMKK23.17136482
4MUSK3.14626145
5NEK13.06220419
6PDK32.81278010
7PDK42.81278010
8MAP3K122.81055313
9BUB12.64715624
10PLK22.54760854
11MAP4K12.25616639
12MKNK12.20903333
13WEE12.14431228
14TEC2.14211523
15LIMK12.13490060
16TXK2.11272771
17FRK2.08395816
18EIF2AK32.05880382
19ACVR1B2.05079151
20TIE12.02900477
21MAPKAPK51.95262783
22EPHA41.90715051
23TRIM281.90153054
24PBK1.85903351
25KIT1.85861439
26ERBB31.84219461
27BRSK11.84179029
28BTK1.69302267
29NTRK31.65946800
30NME21.59725315
31VRK11.59596500
32MET1.59044678
33CDK191.58619677
34CDC71.54566813
35PNCK1.54396150
36TNK21.47989317
37ERBB41.44438516
38TSSK61.43010753
39PDK21.42581596
40BCR1.41288593
41TGFBR21.38313672
42IRAK41.37296645
43STK391.34571033
44CCNB11.32324597
45PHKG11.31139426
46PHKG21.31139426
47SYK1.30574170
48OBSCN1.30038633
49CAMKK11.29777942
50PIM21.25804898
51TNIK1.23922763
52PAK61.22598121
53EIF2AK11.18727106
54ZAP701.17470055
55CDK81.13037296
56PAK31.12016818
57MARK11.07332490
58PRKCE1.06305492
59DAPK11.05683944
60JAK31.04193551
61MINK11.04065178
62CSF1R1.03766344
63SCYL21.03556663
64MAP2K61.02291605
65PTK2B1.01588921
66MST41.01382388
67FER0.99732016
68MAPK130.96244279
69PLK30.95402163
70FLT30.93656497
71PASK0.93283905
72BMPR1B0.92352648
73CAMK2G0.92160529
74CAMK2D0.91360921
75PKN10.91358252
76MOS0.90456669
77MAP2K70.89306520
78ATR0.89008274
79AKT30.87402280
80IKBKE0.86597663
81FES0.85763234
82MAP2K30.85166398
83NTRK10.84026995
84CDK70.83057850
85CAMK2A0.83044204
86IKBKB0.82969378
87DAPK20.82542404
88ROCK10.81979163
89WNK40.80538156
90CSNK1G20.80413489
91PIK3CA0.79760118
92TBK10.79740263
93TYK20.79170661
94PIK3CG0.79113376
95WNK30.78990494
96PDK10.78218923
97DMPK0.77961781
98LATS20.77060539
99MYLK0.76707351
100LYN0.76083811
101MATK0.75823173
102RIPK40.75620708
103MKNK20.72107594
104EPHB20.71622846
105GRK50.71542153
106STK30.71344244
107MAP3K20.71233878
108RPS6KA60.70651939
109STK38L0.69138268
110TRPM70.68213830
111NEK90.67541806
112SRPK10.67009893
113MAP3K140.65735363
114RPS6KA40.65439801
115PLK40.65236242
116KDR0.64444051
117CAMK2B0.64264540
118ILK0.64239918
119RPS6KL10.63565169
120RPS6KC10.63565169
121ROCK20.63295873
122TESK10.63213617
123CLK10.62952158
124PIM10.60842465
125CSNK1G30.60812290
126PLK10.60068876
127CSNK1G10.59424996
128LMTK20.59302152
129PTK20.58795933
130MAPK40.58791578
131LCK0.58760529
132CASK0.58597921
133TGFBR10.58293908
134NME10.58005073
135BMPR20.56774121
136STK380.56425485
137BLK0.56016176
138MAP3K40.55601397
139RPS6KB10.55086470
140MST1R0.54956243
141PRKCG0.53995902
142GRK10.53226163
143CSNK1A1L0.51650928
144PAK20.51276525
145OXSR10.49465133
146TESK20.49096764
147RAF10.48745450
148GRK70.48177240
149STK240.47378640
150ABL20.45973552
151CSNK2A10.45014894
152CDK40.44399665
153ADRBK10.43994187
154ITK0.42967976
155INSRR0.42692780
156IRAK30.42534956
157CDK30.42230155
158TAOK30.42216392
159CAMK10.42132339
160CDK140.40091814
161PAK40.37698789
162MAP3K130.36986771
163BCKDK0.36959133
164RPS6KA20.36301271
165CSNK2A20.35507980
166PINK10.34540197
167RPS6KA50.33798506
168ARAF0.33645497
169HCK0.31431937
170IRAK10.30263251
171ADRBK20.30060783

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.69057480
2Proteasome_Homo sapiens_hsa030503.58691325
3Mismatch repair_Homo sapiens_hsa034303.27860459
4Ribosome_Homo sapiens_hsa030102.96131346
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.55226579
6Homologous recombination_Homo sapiens_hsa034402.52749706
7Nucleotide excision repair_Homo sapiens_hsa034202.50475030
8Fatty acid elongation_Homo sapiens_hsa000622.39094552
9Base excision repair_Homo sapiens_hsa034102.30693860
10Pyrimidine metabolism_Homo sapiens_hsa002402.30530126
11Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.26912387
12RNA polymerase_Homo sapiens_hsa030202.26310533
13Primary immunodeficiency_Homo sapiens_hsa053402.21922837
14Spliceosome_Homo sapiens_hsa030401.90540080
15Protein export_Homo sapiens_hsa030601.89366161
16Basal transcription factors_Homo sapiens_hsa030221.86063508
17Antigen processing and presentation_Homo sapiens_hsa046121.81733567
18Parkinsons disease_Homo sapiens_hsa050121.81439379
19RNA degradation_Homo sapiens_hsa030181.79950404
20Purine metabolism_Homo sapiens_hsa002301.78675202
21Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.75622886
22RNA transport_Homo sapiens_hsa030131.74462603
23Oxidative phosphorylation_Homo sapiens_hsa001901.70283924
24Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.66328110
25Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.66024282
26Fanconi anemia pathway_Homo sapiens_hsa034601.60170868
27Sulfur metabolism_Homo sapiens_hsa009201.58920661
28Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.57237863
29Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.57038017
30SNARE interactions in vesicular transport_Homo sapiens_hsa041301.54336472
31Huntingtons disease_Homo sapiens_hsa050161.53859975
32Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.52586428
33Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.51536081
34Circadian rhythm_Homo sapiens_hsa047101.49755852
35ECM-receptor interaction_Homo sapiens_hsa045121.43643620
36Primary bile acid biosynthesis_Homo sapiens_hsa001201.40239369
37Pentose phosphate pathway_Homo sapiens_hsa000301.39287930
38Synaptic vesicle cycle_Homo sapiens_hsa047211.38555410
39Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.38422987
40Dilated cardiomyopathy_Homo sapiens_hsa054141.35873063
41Fatty acid metabolism_Homo sapiens_hsa012121.34313500
42Cell cycle_Homo sapiens_hsa041101.34055915
432-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.31573736
44Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.29383839
45Cardiac muscle contraction_Homo sapiens_hsa042601.26733224
46Butanoate metabolism_Homo sapiens_hsa006501.22702654
47Hematopoietic cell lineage_Homo sapiens_hsa046401.22513625
48Alzheimers disease_Homo sapiens_hsa050101.22337910
49Legionellosis_Homo sapiens_hsa051341.21668029
50N-Glycan biosynthesis_Homo sapiens_hsa005101.18853325
51Measles_Homo sapiens_hsa051621.18070329
52Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.16955954
53Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.16336407
54Non-homologous end-joining_Homo sapiens_hsa034501.14318807
55Peroxisome_Homo sapiens_hsa041461.13972974
56Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.12133585
57Circadian entrainment_Homo sapiens_hsa047131.11930099
58Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.09008109
59Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.08909489
60Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.07955878
61Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.07540341
62GABAergic synapse_Homo sapiens_hsa047271.06686222
63Vibrio cholerae infection_Homo sapiens_hsa051101.05027277
64Fatty acid degradation_Homo sapiens_hsa000711.04904215
65beta-Alanine metabolism_Homo sapiens_hsa004101.04719361
66Herpes simplex infection_Homo sapiens_hsa051681.02630884
67Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.02626103
68Cysteine and methionine metabolism_Homo sapiens_hsa002701.00834245
69RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.00244370
70Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.99995024
71TGF-beta signaling pathway_Homo sapiens_hsa043500.99408777
72Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.98770785
73Allograft rejection_Homo sapiens_hsa053300.98694123
74Nitrogen metabolism_Homo sapiens_hsa009100.97638828
75Mineral absorption_Homo sapiens_hsa049780.96171125
76Epstein-Barr virus infection_Homo sapiens_hsa051690.93663047
77Steroid biosynthesis_Homo sapiens_hsa001000.91173646
78Leishmaniasis_Homo sapiens_hsa051400.90900763
79NOD-like receptor signaling pathway_Homo sapiens_hsa046210.89823342
80Arginine and proline metabolism_Homo sapiens_hsa003300.89786242
81Glutathione metabolism_Homo sapiens_hsa004800.88283107
82Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.87424919
83Insulin secretion_Homo sapiens_hsa049110.87224424
84Amphetamine addiction_Homo sapiens_hsa050310.86241073
85B cell receptor signaling pathway_Homo sapiens_hsa046620.84564818
86Graft-versus-host disease_Homo sapiens_hsa053320.83625053
87Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.83299012
88Nicotine addiction_Homo sapiens_hsa050330.82468277
89Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.81987607
90Vitamin B6 metabolism_Homo sapiens_hsa007500.81806204
91Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.81544982
92Intestinal immune network for IgA production_Homo sapiens_hsa046720.81211658
93Dopaminergic synapse_Homo sapiens_hsa047280.80993067
94Type I diabetes mellitus_Homo sapiens_hsa049400.79081520
95Gastric acid secretion_Homo sapiens_hsa049710.78745538
96Morphine addiction_Homo sapiens_hsa050320.78637000
97Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.78330637
98Focal adhesion_Homo sapiens_hsa045100.78236639
99Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.73739601
100Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.73308640
101Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.70616954
102Other glycan degradation_Homo sapiens_hsa005110.70415756
103Renin secretion_Homo sapiens_hsa049240.69788143
104Pancreatic secretion_Homo sapiens_hsa049720.69544493
105Collecting duct acid secretion_Homo sapiens_hsa049660.69432511
106Shigellosis_Homo sapiens_hsa051310.69003080
107Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.68719899
108Glutamatergic synapse_Homo sapiens_hsa047240.68663342
109Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.68393309
110Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.68182321
111Platelet activation_Homo sapiens_hsa046110.67165008
112Salivary secretion_Homo sapiens_hsa049700.66823792
113NF-kappa B signaling pathway_Homo sapiens_hsa040640.66009354
114Viral myocarditis_Homo sapiens_hsa054160.65750951
115Oocyte meiosis_Homo sapiens_hsa041140.63953274
116Osteoclast differentiation_Homo sapiens_hsa043800.63769194
117PPAR signaling pathway_Homo sapiens_hsa033200.63691711
118Sphingolipid metabolism_Homo sapiens_hsa006000.60881584
119Gap junction_Homo sapiens_hsa045400.59914163
120T cell receptor signaling pathway_Homo sapiens_hsa046600.57861378
121cGMP-PKG signaling pathway_Homo sapiens_hsa040220.57716967
122Thyroid hormone synthesis_Homo sapiens_hsa049180.57109149
123Long-term potentiation_Homo sapiens_hsa047200.56461200
124Calcium signaling pathway_Homo sapiens_hsa040200.56013756
125Influenza A_Homo sapiens_hsa051640.55910626
126Fructose and mannose metabolism_Homo sapiens_hsa000510.55423675
127Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.53352442
128Jak-STAT signaling pathway_Homo sapiens_hsa046300.52877391
129Malaria_Homo sapiens_hsa051440.50205480
130Folate biosynthesis_Homo sapiens_hsa007900.50132735
131Pyruvate metabolism_Homo sapiens_hsa006200.50053787
132Hepatitis B_Homo sapiens_hsa051610.49890255
133p53 signaling pathway_Homo sapiens_hsa041150.49663520
134Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.49405426
135Carbon metabolism_Homo sapiens_hsa012000.48680059
136Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.48208846
137Rheumatoid arthritis_Homo sapiens_hsa053230.48115229
138Oxytocin signaling pathway_Homo sapiens_hsa049210.47521789
139Pertussis_Homo sapiens_hsa051330.47245900
140Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.47236892
141Phagosome_Homo sapiens_hsa041450.47095959
142Olfactory transduction_Homo sapiens_hsa047400.46338765
143Glycosaminoglycan degradation_Homo sapiens_hsa005310.46333619
144Tyrosine metabolism_Homo sapiens_hsa003500.46264065
145Viral carcinogenesis_Homo sapiens_hsa052030.45808278
146Toll-like receptor signaling pathway_Homo sapiens_hsa046200.45387910
147Apoptosis_Homo sapiens_hsa042100.44901079
148Tuberculosis_Homo sapiens_hsa051520.43267765
149Galactose metabolism_Homo sapiens_hsa000520.42560476
150Salmonella infection_Homo sapiens_hsa051320.42277550
151Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.41047245
152Transcriptional misregulation in cancer_Homo sapiens_hsa052020.40767700
153Serotonergic synapse_Homo sapiens_hsa047260.40724230
154Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.40278180
155Propanoate metabolism_Homo sapiens_hsa006400.38864948
156Metabolic pathways_Homo sapiens_hsa011000.36804743
157Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.35611809
158Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.35113733
159Toxoplasmosis_Homo sapiens_hsa051450.32530597
160One carbon pool by folate_Homo sapiens_hsa006700.30491757
161Biosynthesis of amino acids_Homo sapiens_hsa012300.30488054
162Sulfur relay system_Homo sapiens_hsa041220.29876949
163Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.28536392
164Asthma_Homo sapiens_hsa053100.28368137
165Arachidonic acid metabolism_Homo sapiens_hsa005900.27308809
166Selenocompound metabolism_Homo sapiens_hsa004500.26849400
167mRNA surveillance pathway_Homo sapiens_hsa030150.26671558

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »