BCL2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1interferon-gamma production (GO:0032609)6.02256683
2antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.49260092
3antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.49260092
4positive regulation of gamma-delta T cell activation (GO:0046645)5.42336477
5negative T cell selection (GO:0043383)5.20436886
6positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)5.18971591
7negative thymic T cell selection (GO:0045060)5.04785858
8response to interleukin-15 (GO:0070672)4.95156915
9antigen processing and presentation of endogenous antigen (GO:0019883)4.76392413
10cellular response to interleukin-15 (GO:0071350)4.61891791
11regulation of B cell receptor signaling pathway (GO:0050855)4.54625186
12positive thymic T cell selection (GO:0045059)4.50254689
13negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.40442628
14negative regulation of cell killing (GO:0031342)4.40442628
15regulation of gamma-delta T cell differentiation (GO:0045586)4.35979425
16positive T cell selection (GO:0043368)4.34473174
17ribosomal small subunit assembly (GO:0000028)4.30231500
18thymic T cell selection (GO:0045061)4.30008756
19tolerance induction (GO:0002507)4.24277336
20T cell selection (GO:0045058)4.08408111
21leukocyte aggregation (GO:0070486)3.97949469
22regulation of T cell receptor signaling pathway (GO:0050856)3.95647409
23mast cell activation (GO:0045576)3.93315586
24germinal center formation (GO:0002467)3.93297593
25regulation of gamma-delta T cell activation (GO:0046643)3.91997163
26regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.91116329
27modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.90199858
28positive regulation by organism of defense response of other organism involved in symbiotic interact3.90199858
29modulation by symbiont of host immune response (GO:0052553)3.90199858
30positive regulation by symbiont of host defense response (GO:0052509)3.90199858
31modulation by symbiont of host defense response (GO:0052031)3.90199858
32modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.90199858
33regulation of isotype switching to IgG isotypes (GO:0048302)3.86665868
34T cell migration (GO:0072678)3.85657338
35* B cell homeostasis (GO:0001782)3.68073855
36regulation of alpha-beta T cell proliferation (GO:0046640)3.64447550
37viral transcription (GO:0019083)3.63709058
38positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.60661729
39definitive hemopoiesis (GO:0060216)3.58937077
40regulation of B cell differentiation (GO:0045577)3.54714266
41regulation of T cell tolerance induction (GO:0002664)3.54326807
42T cell receptor signaling pathway (GO:0050852)3.49425046
43histone H3-K36 demethylation (GO:0070544)3.49316887
44Peyers patch development (GO:0048541)3.49293273
45mucosal-associated lymphoid tissue development (GO:0048537)3.49293273
46* CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)3.49063257
47negative regulation of phagocytosis (GO:0050765)3.46901084
48macrophage activation involved in immune response (GO:0002281)3.44425339
49NIK/NF-kappaB signaling (GO:0038061)3.43389309
50translational termination (GO:0006415)3.41117796
51alpha-beta T cell activation (GO:0046631)3.40987501
52antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.40783161
53mature B cell differentiation (GO:0002335)3.36278434
54alpha-beta T cell differentiation (GO:0046632)3.36152477
55positive regulation of granulocyte differentiation (GO:0030854)3.35998798
56defense response to protozoan (GO:0042832)3.35845133
57positive regulation of alpha-beta T cell proliferation (GO:0046641)3.33294408
58* B cell proliferation (GO:0042100)3.31796325
59* antigen receptor-mediated signaling pathway (GO:0050851)3.29933016
60mast cell activation involved in immune response (GO:0002279)3.29894526
61mast cell degranulation (GO:0043303)3.29894526
62* T cell differentiation (GO:0030217)3.29599682
63regulation of regulatory T cell differentiation (GO:0045589)3.28408169
64negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)3.26047099
65negative regulation of T cell receptor signaling pathway (GO:0050860)3.25547047
66interferon-gamma-mediated signaling pathway (GO:0060333)3.24766960
67response to muramyl dipeptide (GO:0032495)3.24712808
68negative regulation of lymphocyte mediated immunity (GO:0002707)3.19011986
69* T cell homeostasis (GO:0043029)3.18528931
70positive regulation of isotype switching (GO:0045830)3.18241857
71positive regulation of humoral immune response (GO:0002922)3.17039128
72T cell costimulation (GO:0031295)3.15037253
73regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.14786029
74negative regulation of B cell proliferation (GO:0030889)3.12765510
75* regulation of B cell proliferation (GO:0030888)3.12136928
76myeloid dendritic cell activation (GO:0001773)3.11804472
77regulation of interferon-beta biosynthetic process (GO:0045357)3.10878174
78detection of bacterium (GO:0016045)3.10763348
79lymphocyte costimulation (GO:0031294)3.10418492
80positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.06586671
81positive regulation of macrophage differentiation (GO:0045651)3.05335752
82positive regulation of B cell differentiation (GO:0045579)3.04657071
83negative regulation of erythrocyte differentiation (GO:0045647)3.04556953
84detection of other organism (GO:0098543)3.04208740
85regulation of granulocyte differentiation (GO:0030852)3.02126067
86regulation of histone H3-K27 methylation (GO:0061085)3.01804519
87phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.01622577
88positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.01490292
89* positive regulation of B cell activation (GO:0050871)3.00981423
90regulation of interleukin-2 biosynthetic process (GO:0045076)3.00347104
91N-acetylneuraminate metabolic process (GO:0006054)2.99319182
92regulation of alpha-beta T cell activation (GO:0046634)2.99084738
93regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370)2.98525818
94tyrosine phosphorylation of STAT protein (GO:0007260)2.95836638
95negative regulation of T cell mediated immunity (GO:0002710)2.94035072
96positive regulation of DNA recombination (GO:0045911)2.93420143
97* positive regulation of B cell proliferation (GO:0030890)2.93417240
98regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.92501050
99* B cell receptor signaling pathway (GO:0050853)2.92167079
100natural killer cell differentiation (GO:0001779)2.91509274
101histone H3-K4 trimethylation (GO:0080182)2.91410290
102activated T cell proliferation (GO:0050798)2.91318517
103regulation of T-helper 1 cell differentiation (GO:0045625)2.90559630
104immunoglobulin mediated immune response (GO:0016064)2.89899107
105regulation of interleukin-12 biosynthetic process (GO:0045075)2.89833992
106SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.87943678
107positive regulation of tolerance induction (GO:0002645)2.87856861
108lymph node development (GO:0048535)2.87054886
109positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.84759123
110positive regulation of defense response to virus by host (GO:0002230)2.84548614
111positive regulation of interleukin-2 production (GO:0032743)2.84263079
112* regulation of B cell activation (GO:0050864)2.82579252
113negative regulation of thymocyte apoptotic process (GO:0070244)2.82413213
114* T cell lineage commitment (GO:0002360)2.82333788
115megakaryocyte development (GO:0035855)2.82203889
116negative regulation of leukocyte mediated immunity (GO:0002704)2.82089878
117cotranslational protein targeting to membrane (GO:0006613)2.80808908
118response to type I interferon (GO:0034340)2.80659691
119myeloid dendritic cell differentiation (GO:0043011)2.80168997
120regulation of isotype switching (GO:0045191)2.79784144
121protein targeting to ER (GO:0045047)2.79103471
122regulation of CD4-positive, alpha-beta T cell activation (GO:2000514)2.78510044
123positive regulation of interferon-alpha production (GO:0032727)2.78402614
124ribosomal small subunit biogenesis (GO:0042274)2.78222955
125* T cell activation (GO:0042110)2.77845212
126regulation of RIG-I signaling pathway (GO:0039535)2.76827364
127response to host immune response (GO:0052572)2.76421335
128response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.76421335
129natural killer cell activation (GO:0030101)2.76333241
130regulation of type I interferon-mediated signaling pathway (GO:0060338)2.76296212
131regulation of alpha-beta T cell differentiation (GO:0046637)2.76035832
132* lymphocyte homeostasis (GO:0002260)2.75663964
133type I interferon signaling pathway (GO:0060337)2.75611371
134cellular response to type I interferon (GO:0071357)2.75611371
135translational elongation (GO:0006414)2.75222325
136embryonic hemopoiesis (GO:0035162)2.74967963
137regulation of natural killer cell mediated immunity (GO:0002715)2.74628274
138regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.74628274
139viral genome replication (GO:0019079)2.72022802
140* lymphocyte differentiation (GO:0030098)2.68500448
141establishment of protein localization to endoplasmic reticulum (GO:0072599)2.66898279
142JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.66082462
143positive regulation of immunoglobulin mediated immune response (GO:0002891)2.64336234
144positive regulation of B cell mediated immunity (GO:0002714)2.64336234
145viral life cycle (GO:0019058)2.63989567
146nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.63404945
147Arp2/3 complex-mediated actin nucleation (GO:0034314)2.61770731
148response to protozoan (GO:0001562)2.59846989
149regulation of response to interferon-gamma (GO:0060330)2.58603031

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* FOXP3_17237761_ChIP-ChIP_TREG_Mouse6.61858083
2E2F7_22180533_ChIP-Seq_HELA_Human6.27494533
3* STAT6_20620947_ChIP-Seq_CD4_POS_T_Human5.58904238
4BP1_19119308_ChIP-ChIP_Hs578T_Human4.91245517
5IRF8_22096565_ChIP-ChIP_GC-B_Human4.59026125
6STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.68288200
7IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.56221853
8SCL_19346495_ChIP-Seq_HPC-7_Human3.54893205
9RUNX_20019798_ChIP-Seq_JUKART_Human3.44443554
10MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.38935708
11STAT4_19710469_ChIP-ChIP_TH1__Mouse3.19197177
12FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse3.07854473
13MYC_22102868_ChIP-Seq_BL_Human3.05193571
14* MYB_26560356_Chip-Seq_TH2_Human2.94427070
15HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.89846469
16IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.87040457
17SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.67755867
18* VDR_21846776_ChIP-Seq_THP-1_Human2.54480004
19SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.52929863
20MAF_26560356_Chip-Seq_TH1_Human2.48664895
21NOTCH1_21737748_ChIP-Seq_TLL_Human2.42144669
22* MYB_26560356_Chip-Seq_TH1_Human2.41592089
23* VDR_24763502_ChIP-Seq_THP-1_Human2.30857229
24ELF1_17652178_ChIP-ChIP_JURKAT_Human2.28870135
25RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.27399305
26IRF8_21731497_ChIP-ChIP_J774_Mouse2.25172865
27SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.22863244
28EGR1_19374776_ChIP-ChIP_THP-1_Human2.20526682
29UTX_26944678_Chip-Seq_JUKART_Human2.19700440
30BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.10500847
31* MYB_21317192_ChIP-Seq_ERMYB_Mouse2.05902641
32* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.96765265
33IRF8_27001747_Chip-Seq_BMDM_Mouse1.95995465
34SPI1_23547873_ChIP-Seq_NB4_Human1.91071311
35RUNX1_22412390_ChIP-Seq_EML_Mouse1.88273364
36TCF7_22412390_ChIP-Seq_EML_Mouse1.82410048
37NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.80141559
38E2F4_17652178_ChIP-ChIP_JURKAT_Human1.80053405
39CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.74224825
40TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.70681202
41ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.69231568
42FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.69192534
43RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.66517953
44* VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.62271016
45* GATA3_27048872_Chip-Seq_THYMUS_Human1.54374371
46TP63_19390658_ChIP-ChIP_HaCaT_Human1.52347669
47* MAF_26560356_Chip-Seq_TH2_Human1.48057925
48MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.48057681
49E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.43692787
50SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.40200353
51* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.39506185
52GATA1_22025678_ChIP-Seq_K562_Human1.38315786
53* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.37275227
54* PU_27001747_Chip-Seq_BMDM_Mouse1.35590858
55SMAD_19615063_ChIP-ChIP_OVARY_Human1.35146165
56AR_21572438_ChIP-Seq_LNCaP_Human1.33774647
57LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.29703923
58ERG_20887958_ChIP-Seq_HPC-7_Mouse1.28070097
59TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.27392201
60SPI1_23127762_ChIP-Seq_K562_Human1.26414370
61* CIITA_25753668_ChIP-Seq_RAJI_Human1.25598357
62GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.25479480
63Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.25310015
64HOXB4_20404135_ChIP-ChIP_EML_Mouse1.25285699
65NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.20551462
66KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.18976130
67ELK1_19687146_ChIP-ChIP_HELA_Human1.18248745
68STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.16512336
69LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.15258085
70GATA2_22383799_ChIP-Seq_G1ME_Mouse1.14166340
71GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.12292627
72TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.11087665
73FOXM1_23109430_ChIP-Seq_U2OS_Human1.07241184
74* VDR_24787735_ChIP-Seq_THP-1_Human1.06288865
75FOXP3_21729870_ChIP-Seq_TREG_Human1.01594384
76VDR_23849224_ChIP-Seq_CD4+_Human0.98954169
77* RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.97256555
78E2F1_21310950_ChIP-Seq_MCF-7_Human0.96425448
79* KDM2B_26808549_Chip-Seq_SUP-B15_Human0.96259194
80PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.95602125
81SMRT_27268052_Chip-Seq_Bcells_Human0.95586561
82* GATA1_22383799_ChIP-Seq_G1ME_Mouse0.95316831
83KDM2B_26808549_Chip-Seq_DND41_Human0.94787241
84KDM2B_26808549_Chip-Seq_JURKAT_Human0.93239036
85RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.92844284
86GATA3_26560356_Chip-Seq_TH2_Human0.91680871
87PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.85699464
88* GATA1_19941827_ChIP-Seq_MEL_Mouse0.85624661
89GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.82004256
90GATA1_19941826_ChIP-Seq_K562_Human0.81906198
91FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.81549587
92NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.80895848
93FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.80199627
94NCOR1_26117541_ChIP-Seq_K562_Human0.77238316
95* PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.75629592
96FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.74631343
97DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.72960585
98SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.72249833
99PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.70378241
100PKCTHETA_26484144_Chip-Seq_BREAST_Human0.70330353
101CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.69650001
102VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.69242087
103* GATA1_19941827_ChIP-Seq_MEL86_Mouse0.68371413
104GATA3_26560356_Chip-Seq_TH1_Human0.67474853
105* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.66632689
106CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.65639162
107RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.65435792
108NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.65017736
109CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.63644988
110TFEB_21752829_ChIP-Seq_HELA_Human0.63169220
111CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.62720935
112CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.62155870
113GATA2_19941826_ChIP-Seq_K562_Human0.61805824
114MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.61216793
115* SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human0.58250600
116MYC_18940864_ChIP-ChIP_HL60_Human0.56912416
117* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.56098985
118PU.1_20513432_ChIP-Seq_Bcells_Mouse0.54997612
119ELK3_25401928_ChIP-Seq_HUVEC_Human0.54661963
120PRDM14_20953172_ChIP-Seq_ESCs_Human0.53104621
121ETS1_22383799_ChIP-Seq_G1ME_Mouse0.52521138
122EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.51463065

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1* MP0003763_abnormal_thymus_physiology4.32658184
2MP0005671_abnormal_response_to3.86103849
3MP0002396_abnormal_hematopoietic_system3.62057297
4MP0001835_abnormal_antigen_presentation3.31421623
5MP0001800_abnormal_humoral_immune2.98140174
6MP0002166_altered_tumor_susceptibility2.93143293
7MP0002398_abnormal_bone_marrow2.69644503
8MP0000685_abnormal_immune_system2.63204755
9* MP0002420_abnormal_adaptive_immunity2.60021546
10MP0005387_immune_system_phenotype2.58937401
11MP0001790_abnormal_immune_system2.58937401
12MP0005000_abnormal_immune_tolerance2.56357446
13* MP0001819_abnormal_immune_cell2.55263331
14MP0002006_tumorigenesis2.51333331
15MP0002723_abnormal_immune_serum2.50553917
16* MP0002452_abnormal_antigen_presenting2.43396686
17MP0002009_preneoplasia2.39707234
18MP0001873_stomach_inflammation2.38554292
19MP0004808_abnormal_hematopoietic_stem2.32982052
20* MP0000703_abnormal_thymus_morphology2.32265439
21* MP0000716_abnormal_immune_system2.25852033
22MP0009785_altered_susceptibility_to2.24766762
23MP0005025_abnormal_response_to2.20777125
24MP0005174_abnormal_tail_pigmentation2.14656938
25* MP0000689_abnormal_spleen_morphology2.14004646
26* MP0002722_abnormal_immune_system2.13577547
27MP0003866_abnormal_defecation2.13071405
28MP0002405_respiratory_system_inflammati2.11217869
29MP0003436_decreased_susceptibility_to2.08766227
30MP0002148_abnormal_hypersensitivity_rea2.03776318
31* MP0005075_abnormal_melanosome_morpholog1.99431132
32MP0003724_increased_susceptibility_to1.98911732
33* MP0009333_abnormal_splenocyte_physiolog1.95891728
34MP0000465_gastrointestinal_hemorrhage1.92700424
35MP0002933_joint_inflammation1.90067971
36MP0005409_darkened_coat_color1.89412944
37MP0002429_abnormal_blood_cell1.89339095
38MP0010155_abnormal_intestine_physiology1.89008809
39MP0003300_gastrointestinal_ulcer1.81848808
40MP0005464_abnormal_platelet_physiology1.76046646
41MP0002138_abnormal_hepatobiliary_system1.75878975
42MP0001853_heart_inflammation1.75646061
43* MP0002419_abnormal_innate_immunity1.73417505
44MP0005451_abnormal_body_composition1.68955601
45MP0000015_abnormal_ear_pigmentation1.58963050
46MP0009379_abnormal_foot_pigmentation1.57887697
47MP0002095_abnormal_skin_pigmentation1.56500208
48MP0001348_abnormal_lacrimal_gland1.54052018
49MP0005397_hematopoietic_system_phenotyp1.47799763
50MP0001545_abnormal_hematopoietic_system1.47799763
51* MP0000490_abnormal_crypts_of1.46663551
52MP0003303_peritoneal_inflammation1.41982225
53MP0001845_abnormal_inflammatory_respons1.36984143
54MP0005076_abnormal_cell_differentiation1.32748102
55MP0003045_fibrosis1.31758007
56MP0000858_altered_metastatic_potential1.30991261
57MP0003183_abnormal_peptide_metabolism1.21319601
58MP0010094_abnormal_chromosome_stability1.21201088
59MP0008057_abnormal_DNA_replication1.19940991
60MP0003091_abnormal_cell_migration1.19728585
61MP0001188_hyperpigmentation1.14150607
62MP0004947_skin_inflammation1.13310515
63MP0009278_abnormal_bone_marrow1.12372715
64MP0001986_abnormal_taste_sensitivity1.08315490
65MP0002998_abnormal_bone_remodeling1.06094472
66MP0002132_abnormal_respiratory_system1.02066823
67* MP0004381_abnormal_hair_follicle1.00040169
68* MP0002019_abnormal_tumor_incidence0.99713848
69MP0009115_abnormal_fat_cell0.91657136
70MP0000569_abnormal_digit_pigmentation0.90297235
71MP0001533_abnormal_skeleton_physiology0.89739396
72MP0004130_abnormal_muscle_cell0.89510839
73MP0003448_altered_tumor_morphology0.89106264
74MP0003221_abnormal_cardiomyocyte_apopto0.87145727
75MP0003172_abnormal_lysosome_physiology0.85834924
76MP0003943_abnormal_hepatobiliary_system0.85223030
77MP0008007_abnormal_cellular_replicative0.83795152
78MP0006082_CNS_inflammation0.82029550
79MP0004185_abnormal_adipocyte_glucose0.81906787
80MP0001851_eye_inflammation0.80964711
81MP0008260_abnormal_autophagy0.79622897
82MP0002163_abnormal_gland_morphology0.79399180
83MP0001663_abnormal_digestive_system0.78832485
84MP0008058_abnormal_DNA_repair0.78331462
85MP0004510_myositis0.75537414
86MP0002332_abnormal_exercise_endurance0.75376957
87MP0000383_abnormal_hair_follicle0.74885958
88MP0008469_abnormal_protein_level0.74723181
89MP0003077_abnormal_cell_cycle0.74296842
90MP0002938_white_spotting0.74019356
91MP0010307_abnormal_tumor_latency0.71806486
92MP0003136_yellow_coat_color0.70400083
93MP0008961_abnormal_basal_metabolism0.69932408
94MP0000249_abnormal_blood_vessel0.69144747
95MP0005666_abnormal_adipose_tissue0.67967457
96MP0003646_muscle_fatigue0.66553117
97MP0009764_decreased_sensitivity_to0.66233402
98MP0003795_abnormal_bone_structure0.65880260
99MP0002089_abnormal_postnatal_growth/wei0.65411524
100MP0005621_abnormal_cell_physiology0.62922630
101MP0000681_abnormal_thyroid_gland0.62652795
102MP0003693_abnormal_embryo_hatching0.61067008
103MP0002693_abnormal_pancreas_physiology0.60979228
104MP0001919_abnormal_reproductive_system0.60367830
105MP0004883_abnormal_blood_vessel0.59319373
106MP0003567_abnormal_fetal_cardiomyocyte0.59055376
107MP0008874_decreased_physiological_sensi0.57705545
108MP0002277_abnormal_respiratory_mucosa0.57122916
109MP0000350_abnormal_cell_proliferation0.56073677
110MP0002877_abnormal_melanocyte_morpholog0.55705573
111MP0003656_abnormal_erythrocyte_physiolo0.54415990
112MP0006292_abnormal_olfactory_placode0.53363522
113* MP0000477_abnormal_intestine_morphology0.53340226
114MP0003868_abnormal_feces_composition0.52880960
115MP0005645_abnormal_hypothalamus_physiol0.52489281
116* MP0002075_abnormal_coat/hair_pigmentati0.52400102
117MP0005266_abnormal_metabolism0.51778340
118MP0005390_skeleton_phenotype0.51706160
119MP0003828_pulmonary_edema0.50225065
120MP0003453_abnormal_keratinocyte_physiol0.49709656
121MP0005379_endocrine/exocrine_gland_phen0.49334792
122MP0002928_abnormal_bile_duct0.48802962
123MP0000343_altered_response_to0.47978564
124MP0000428_abnormal_craniofacial_morphol0.47711389
125MP0002113_abnormal_skeleton_development0.47666941
126MP0009250_abnormal_appendicular_skeleto0.44197462
127MP0005310_abnormal_salivary_gland0.43858664
128MP0005023_abnormal_wound_healing0.42397672
129MP0000313_abnormal_cell_death0.41277183
130MP0010352_gastrointestinal_tract_polyps0.40702449
131MP0008569_lethality_at_weaning0.39806409
132MP0009763_increased_sensitivity_to0.39652425

Predicted human phenotypes

RankGene SetZ-score
1IgM deficiency (HP:0002850)5.27888328
2Elevated erythrocyte sedimentation rate (HP:0003565)5.13453915
3Colitis (HP:0002583)5.07280507
4Chronic otitis media (HP:0000389)4.53869984
5T lymphocytopenia (HP:0005403)4.44380681
6Myositis (HP:0100614)4.43968415
7Abnormality of T cell number (HP:0011839)4.15349228
8Abnormality of T cells (HP:0002843)3.78137626
9Recurrent bronchitis (HP:0002837)3.71466395
10Recurrent viral infections (HP:0004429)3.67874714
11Selective tooth agenesis (HP:0001592)3.64728405
12Abnormal delayed hypersensitivity skin test (HP:0002963)3.49881165
13Abnormality of the fingertips (HP:0001211)3.44356140
14Panhypogammaglobulinemia (HP:0003139)3.42796566
15Recurrent fungal infections (HP:0002841)3.36835981
16Papilloma (HP:0012740)3.30493486
17Verrucae (HP:0200043)3.30493486
18Viral hepatitis (HP:0006562)3.29459710
19Stomatitis (HP:0010280)3.27978957
20IgG deficiency (HP:0004315)3.23841699
21Chronic mucocutaneous candidiasis (HP:0002728)3.18711450
22Recurrent cutaneous fungal infections (HP:0011370)3.18711450
23Agammaglobulinemia (HP:0004432)3.16753062
24* Meningitis (HP:0001287)3.15480391
25Abnormality of the prostate (HP:0008775)3.14827719
26Abnormality of T cell physiology (HP:0011840)3.10570087
27Thrombocytosis (HP:0001894)3.08009189
28Vasculitis (HP:0002633)2.87694325
29IgA deficiency (HP:0002720)2.86597746
30Lymphopenia (HP:0001888)2.86069851
31Emphysema (HP:0002097)2.83696398
32Optic neuritis (HP:0100653)2.82389078
33Retrobulbar optic neuritis (HP:0100654)2.82389078
34Nasal polyposis (HP:0100582)2.81169370
35Restrictive lung disease (HP:0002091)2.81117891
36Prolonged bleeding time (HP:0003010)2.80767468
37Chronic diarrhea (HP:0002028)2.76529337
38Osteomyelitis (HP:0002754)2.71458131
39Basal cell carcinoma (HP:0002671)2.71323538
40Abnormality of cells of the lymphoid lineage (HP:0012140)2.67521622
41Orchitis (HP:0100796)2.66432610
42Hypoplasia of the thymus (HP:0000778)2.62222346
43Petechiae (HP:0000967)2.57539656
44Obstructive lung disease (HP:0006536)2.50396721
45Chronic obstructive pulmonary disease (HP:0006510)2.50396721
46Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.49842254
47* Lymphoma (HP:0002665)2.49580562
48Abnormal number of incisors (HP:0011064)2.48802721
49Recurrent abscess formation (HP:0002722)2.48547937
50Reticulocytopenia (HP:0001896)2.47224539
51B lymphocytopenia (HP:0010976)2.43963654
52Abnormality of B cell number (HP:0010975)2.43963654
53Inflammation of the large intestine (HP:0002037)2.43632878
54Fatigue (HP:0012378)2.43092425
55Gastrointestinal inflammation (HP:0004386)2.39518513
56Sepsis (HP:0100806)2.38426798
57Spontaneous hematomas (HP:0007420)2.37916296
58Hemoptysis (HP:0002105)2.37358853
59Encephalitis (HP:0002383)2.36999206
60Pulmonary infiltrates (HP:0002113)2.36524229
61Severe combined immunodeficiency (HP:0004430)2.34637108
62Abnormality of the nasal mucosa (HP:0000433)2.33514421
63* Mediastinal lymphadenopathy (HP:0100721)2.33078710
64Abnormality of macrophages (HP:0004311)2.30173022
65Recurrent lower respiratory tract infections (HP:0002783)2.29880150
66Eosinophilia (HP:0001880)2.26151913
67Abnormality of eosinophils (HP:0001879)2.25567524
68Acute myeloid leukemia (HP:0004808)2.25544102
69Bronchitis (HP:0012387)2.23980917
70Abnormality of the columella (HP:0009929)2.22751160
71Eczematoid dermatitis (HP:0000976)2.22284525
72Slow saccadic eye movements (HP:0000514)2.22105508
73Abnormal number of erythroid precursors (HP:0012131)2.21922947
74Recurrent pneumonia (HP:0006532)2.21600933
75Increased IgM level (HP:0003496)2.19677081
76Gastrointestinal infarctions (HP:0005244)2.18675393
77Abnormality of cells of the erythroid lineage (HP:0012130)2.18401302
78Hepatitis (HP:0012115)2.17529749
79Spinal cord lesions (HP:0100561)2.16779095
80Syringomyelia (HP:0003396)2.16779095
81Autoimmune hemolytic anemia (HP:0001890)2.15821637
82Chronic sinusitis (HP:0011109)2.15376112
83Prostate neoplasm (HP:0100787)2.11985997
84Pulmonary fibrosis (HP:0002206)2.11073257
85Gastrointestinal stroma tumor (HP:0100723)2.08373659
86Cellulitis (HP:0100658)2.07264162
87Thyroiditis (HP:0100646)2.07046748
88Recurrent sinusitis (HP:0011108)2.06415787
89Recurrent skin infections (HP:0001581)2.05303886
90Gingivitis (HP:0000230)2.05261156
91Short 4th metacarpal (HP:0010044)2.04023780
92Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.04023780
93Leukocytosis (HP:0001974)2.03920592
94Papilledema (HP:0001085)2.03635733
95Aplastic anemia (HP:0001915)2.02671581
96Epistaxis (HP:0000421)2.02279733
97Chest pain (HP:0100749)1.99458390
98Granulocytopenia (HP:0001913)1.98522158
99Dysmetric saccades (HP:0000641)1.98395960
10011 pairs of ribs (HP:0000878)1.95279961
101Keratoconjunctivitis sicca (HP:0001097)1.93410898
102Thoracolumbar scoliosis (HP:0002944)1.93020888
103Basal ganglia calcification (HP:0002135)1.93019585
104Keratoconjunctivitis (HP:0001096)1.92835049
105Increased density of long bones (HP:0006392)1.92149697
106Pustule (HP:0200039)1.91854329
107Combined immunodeficiency (HP:0005387)1.91738159
108Leukopenia (HP:0001882)1.90850889
109Aplasia/Hypoplasia of the thymus (HP:0010515)1.90240324
110Ureteral stenosis (HP:0000071)1.90063675
111Cheilitis (HP:0100825)1.89589228
112Recurrent bacterial skin infections (HP:0005406)1.89365447
113Hypergammaglobulinemia (HP:0010702)1.89210223
114Trigonocephaly (HP:0000243)1.87634890
115Recurrent gram-negative bacterial infections (HP:0005420)1.87305431
116Arterial thrombosis (HP:0004420)1.86717441
117Narrow palate (HP:0000189)1.85278799
118Increased IgE level (HP:0003212)1.84428291
119Recurrent otitis media (HP:0000403)1.81326540
120Pulmonary embolism (HP:0002204)1.81324688
121Acute lymphatic leukemia (HP:0006721)1.80581102
122Abnormality of the parietal bone (HP:0002696)1.80559734
123Arthralgia (HP:0002829)1.80553946
124Skin rash (HP:0000988)1.80423405
125Urticaria (HP:0001025)1.79188218
126Autoimmune thrombocytopenia (HP:0001973)1.79170238
127Abnormality of the incisor (HP:0000676)1.77403758
128Clubbing of toes (HP:0100760)1.76886278
129Skin ulcer (HP:0200042)1.76602048
130Midline defect of the nose (HP:0004122)1.74525428
131Joint swelling (HP:0001386)1.74261648
132Prominent nose (HP:0000448)1.74220503
133Subacute progressive viral hepatitis (HP:0006572)1.71581469

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K15.06486976
2TXK4.85143212
3PRPF4B3.82375941
4RIPK43.78329569
5CLK13.04006079
6TEC2.67509882
7MKNK22.67085715
8JAK32.40812270
9ITK2.27349667
10KIT2.23629762
11ZAP702.22898268
12NME22.05733983
13BTK1.96826790
14NLK1.95957658
15TRIB31.90350939
16TYK21.87923714
17STK101.87075287
18IKBKE1.86935862
19CDK121.79896057
20EEF2K1.76589718
21FGFR31.69138990
22MKNK11.68978048
23IRAK41.65697220
24TNIK1.65134081
25MAP3K141.61988924
26SYK1.58455056
27SMG11.56496210
28LCK1.54599073
29JAK11.50409885
30FES1.45519216
31PIM11.45274381
32GRK61.41895213
33BMPR21.41663785
34TBK11.36462397
35HCK1.32820857
36MAPK111.32619827
37ERN11.30210391
38MUSK1.25128024
39IRAK31.24342133
40YES11.21258267
41MAPK121.18548586
42PASK1.18398389
43SIK31.17460184
44IKBKB1.16035349
45MST41.14962717
46MAP3K131.14786007
47FGFR41.14647499
48SRPK11.12867833
49TNK21.12759672
50TLK11.11425829
51MELK1.09088490
52HIPK21.08170814
53CSF1R1.00633256
54LRRK20.98099323
55LYN0.97687922
56SIK20.93303152
57CSK0.92080414
58IRAK10.89008919
59ICK0.87158365
60MAPK70.87120268
61CDC70.86938659
62BLK0.86534240
63PDK10.86221721
64PRKCQ0.85429326
65TAOK30.85416752
66EPHA30.84122725
67PIK3CG0.83250184
68RPS6KA40.83039026
69MAP3K100.81947152
70CAMKK10.81424919
71CDC42BPA0.79856399
72CDK40.78034287
73CHUK0.74439744
74VRK10.73941179
75MARK30.73493560
76TGFBR20.72598015
77PIM20.70226729
78SGK30.69486550
79PKN20.69484100
80CASK0.67171377
81PRKD20.66383893
82SIK10.65379565
83MAP2K30.64094839
84MAP3K70.63574139
85JAK20.62007604
86ATR0.61866774
87OBSCN0.61707707
88CDK60.57312290
89MAP3K10.55043016
90RPS6KA60.54744857
91CDK80.54740388
92TRPM70.53454881
93STK240.53041034
94FLT30.51236807
95CAMKK20.50659568
96MAP3K120.50453970
97STK40.49966672
98RET0.49346744
99STK160.49269947
100KDR0.49245360
101TGFBR10.48237524
102MAP2K60.47998742
103NEK90.45373479
104RPS6KB20.44091448
105SCYL20.43424661
106KSR20.41563836
107FGR0.40247040
108RPS6KC10.39641767
109RPS6KL10.39641767
110CDK90.39300030
111PDPK10.39100879
112UHMK10.38156079
113MATK0.38047898
114* MAPK40.37693686
115TAOK20.37060242
116MAP3K60.36636409
117CDK70.35724809
118SGK20.35240750
119BRD40.32488805
120WNK10.31914426
121NUAK10.30932326
122FYN0.30735073
123SGK2230.30682183
124SGK4940.30682183
125IRAK20.30622602
126ADRBK20.30314079
127RPS6KA50.29379482
128STK30.28913585
129CAMK40.28835343
130EIF2AK30.28173033
131TTN0.28158085
132PRKCH0.28117513
133RPS6KB10.28017903
134MAP2K20.27526036
135IGF1R0.27449897
136CAMK10.26600232
137MARK20.26486305
138EIF2AK20.25860521

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053403.77063683
2Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.59338099
3Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.47703248
4Measles_Homo sapiens_hsa051622.42539462
5T cell receptor signaling pathway_Homo sapiens_hsa046602.35316999
6DNA replication_Homo sapiens_hsa030302.28817358
7Ribosome_Homo sapiens_hsa030102.28477229
8Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046502.17461038
9Hematopoietic cell lineage_Homo sapiens_hsa046402.10573783
10* NF-kappa B signaling pathway_Homo sapiens_hsa040642.02669603
11Intestinal immune network for IgA production_Homo sapiens_hsa046721.99477177
12Graft-versus-host disease_Homo sapiens_hsa053321.91416687
13Allograft rejection_Homo sapiens_hsa053301.87884759
14Homologous recombination_Homo sapiens_hsa034401.80882050
15Herpes simplex infection_Homo sapiens_hsa051681.73848167
16Antigen processing and presentation_Homo sapiens_hsa046121.70548672
17B cell receptor signaling pathway_Homo sapiens_hsa046621.68925149
18* Jak-STAT signaling pathway_Homo sapiens_hsa046301.63915039
19Osteoclast differentiation_Homo sapiens_hsa043801.63789461
20Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.61962939
21RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.61946752
22Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.60629062
23Leishmaniasis_Homo sapiens_hsa051401.60329466
24Mismatch repair_Homo sapiens_hsa034301.52674863
25Autoimmune thyroid disease_Homo sapiens_hsa053201.51837093
26Base excision repair_Homo sapiens_hsa034101.48915459
27Staphylococcus aureus infection_Homo sapiens_hsa051501.43118071
28Viral myocarditis_Homo sapiens_hsa054161.31161491
29Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.30314892
30Spliceosome_Homo sapiens_hsa030401.29015408
31Transcriptional misregulation in cancer_Homo sapiens_hsa052021.25739378
32* Hepatitis B_Homo sapiens_hsa051611.25186102
33Non-homologous end-joining_Homo sapiens_hsa034501.24227002
34Acute myeloid leukemia_Homo sapiens_hsa052211.23652964
35NOD-like receptor signaling pathway_Homo sapiens_hsa046211.23445712
36Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.19982706
37Fanconi anemia pathway_Homo sapiens_hsa034601.19265114
38Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.17406604
39Toll-like receptor signaling pathway_Homo sapiens_hsa046201.15431228
40* Toxoplasmosis_Homo sapiens_hsa051451.08400666
41Asthma_Homo sapiens_hsa053101.07640655
42HTLV-I infection_Homo sapiens_hsa051661.06047659
43Influenza A_Homo sapiens_hsa051641.05900175
44Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.05189987
45Renal cell carcinoma_Homo sapiens_hsa052111.02249544
46Chemokine signaling pathway_Homo sapiens_hsa040621.01872300
47Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.01547332
48Platelet activation_Homo sapiens_hsa046110.96771680
49Chronic myeloid leukemia_Homo sapiens_hsa052200.95038177
50TNF signaling pathway_Homo sapiens_hsa046680.94746494
51VEGF signaling pathway_Homo sapiens_hsa043700.93841934
52mTOR signaling pathway_Homo sapiens_hsa041500.92229629
53Leukocyte transendothelial migration_Homo sapiens_hsa046700.90484364
54Endometrial cancer_Homo sapiens_hsa052130.90370102
55Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.88280639
56Systemic lupus erythematosus_Homo sapiens_hsa053220.87614244
57Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.87210293
58* Small cell lung cancer_Homo sapiens_hsa052220.86775694
59Notch signaling pathway_Homo sapiens_hsa043300.85477893
60Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.84943029
61Rheumatoid arthritis_Homo sapiens_hsa053230.83902210
62Cell cycle_Homo sapiens_hsa041100.83422902
63RNA degradation_Homo sapiens_hsa030180.82278372
64* AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.81746996
65Pancreatic cancer_Homo sapiens_hsa052120.80906099
66p53 signaling pathway_Homo sapiens_hsa041150.80370577
67Malaria_Homo sapiens_hsa051440.79407115
68Shigellosis_Homo sapiens_hsa051310.77767080
69* Apoptosis_Homo sapiens_hsa042100.76577912
70* Epstein-Barr virus infection_Homo sapiens_hsa051690.75354117
71Viral carcinogenesis_Homo sapiens_hsa052030.74396584
72Glioma_Homo sapiens_hsa052140.73318865
73N-Glycan biosynthesis_Homo sapiens_hsa005100.72696866
74Hepatitis C_Homo sapiens_hsa051600.71517857
75Type I diabetes mellitus_Homo sapiens_hsa049400.71203394
76Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.69514335
77ErbB signaling pathway_Homo sapiens_hsa040120.68864745
78Choline metabolism in cancer_Homo sapiens_hsa052310.68287007
79Dorso-ventral axis formation_Homo sapiens_hsa043200.64949837
80Insulin resistance_Homo sapiens_hsa049310.64880835
81Phospholipase D signaling pathway_Homo sapiens_hsa040720.63571478
82* Colorectal cancer_Homo sapiens_hsa052100.62951385
83GnRH signaling pathway_Homo sapiens_hsa049120.62430803
84Type II diabetes mellitus_Homo sapiens_hsa049300.62066347
85Prolactin signaling pathway_Homo sapiens_hsa049170.61157320
86Non-small cell lung cancer_Homo sapiens_hsa052230.60169194
87Longevity regulating pathway - mammal_Homo sapiens_hsa042110.59969964
88Thyroid cancer_Homo sapiens_hsa052160.59817110
89Nucleotide excision repair_Homo sapiens_hsa034200.59002400
90* Pathways in cancer_Homo sapiens_hsa052000.57861056
91Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.57401559
92Pertussis_Homo sapiens_hsa051330.57142300
93Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.55811168
94* Tuberculosis_Homo sapiens_hsa051520.55734864
95* Neurotrophin signaling pathway_Homo sapiens_hsa047220.55519873
96Carbohydrate digestion and absorption_Homo sapiens_hsa049730.55042988
97Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.52939013
98Long-term potentiation_Homo sapiens_hsa047200.52833727
99Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.51566979
100African trypanosomiasis_Homo sapiens_hsa051430.51041410
101Adipocytokine signaling pathway_Homo sapiens_hsa049200.50688144
102Phosphatidylinositol signaling system_Homo sapiens_hsa040700.48955808
103Insulin signaling pathway_Homo sapiens_hsa049100.48025344
104* MicroRNAs in cancer_Homo sapiens_hsa052060.47624720
105Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.45351523
106MAPK signaling pathway_Homo sapiens_hsa040100.45255383
107Inositol phosphate metabolism_Homo sapiens_hsa005620.44859714
108Wnt signaling pathway_Homo sapiens_hsa043100.44507319
109* Prostate cancer_Homo sapiens_hsa052150.43592781
110Estrogen signaling pathway_Homo sapiens_hsa049150.43521037
111* HIF-1 signaling pathway_Homo sapiens_hsa040660.43484617
112Pyrimidine metabolism_Homo sapiens_hsa002400.41955909
113Other glycan degradation_Homo sapiens_hsa005110.40873627
114Salmonella infection_Homo sapiens_hsa051320.40363244
115mRNA surveillance pathway_Homo sapiens_hsa030150.40144217
116Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.39812578
117Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.38619835
118Regulation of actin cytoskeleton_Homo sapiens_hsa048100.38539163
119Thyroid hormone signaling pathway_Homo sapiens_hsa049190.35066202
120One carbon pool by folate_Homo sapiens_hsa006700.34922895
121Legionellosis_Homo sapiens_hsa051340.32905250
122* PI3K-Akt signaling pathway_Homo sapiens_hsa041510.32252443
123Basal transcription factors_Homo sapiens_hsa030220.32222685
124FoxO signaling pathway_Homo sapiens_hsa040680.32131154
125* Sphingolipid signaling pathway_Homo sapiens_hsa040710.29797214
126Phagosome_Homo sapiens_hsa041450.28782587
127Basal cell carcinoma_Homo sapiens_hsa052170.27980410
128Lysine degradation_Homo sapiens_hsa003100.27219610
129Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.26776117
130cGMP-PKG signaling pathway_Homo sapiens_hsa040220.26685369
131Oxytocin signaling pathway_Homo sapiens_hsa049210.24189395

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