BCL2L15

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cerebellar granule cell differentiation (GO:0021707)6.78082177
2L-fucose catabolic process (GO:0042355)5.82040976
3fucose catabolic process (GO:0019317)5.82040976
4L-fucose metabolic process (GO:0042354)5.82040976
5cellular anion homeostasis (GO:0030002)5.37099306
6regulation of guanylate cyclase activity (GO:0031282)5.28012882
7response to pheromone (GO:0019236)5.26122895
8intestinal absorption (GO:0050892)4.68567533
9sulfate transmembrane transport (GO:1902358)4.54488879
10positive regulation of guanylate cyclase activity (GO:0031284)4.51536184
11angiotensin maturation (GO:0002003)4.43015068
12behavioral response to nicotine (GO:0035095)4.30998842
13G-protein coupled glutamate receptor signaling pathway (GO:0007216)4.30456942
14desmosome organization (GO:0002934)4.14916006
15hemidesmosome assembly (GO:0031581)4.12614987
16intestinal cholesterol absorption (GO:0030299)4.09369573
17regulation of vascular endothelial growth factor signaling pathway (GO:1900746)4.08814291
18maintenance of gastrointestinal epithelium (GO:0030277)4.07257468
19cerebellar Purkinje cell differentiation (GO:0021702)4.04696677
20O-glycan processing (GO:0016266)4.04353222
21cell differentiation in hindbrain (GO:0021533)3.98296083
22sulfate transport (GO:0008272)3.91215093
23negative regulation of keratinocyte proliferation (GO:0010839)3.90846440
24exogenous drug catabolic process (GO:0042738)3.87514738
25cellular potassium ion homeostasis (GO:0030007)3.86729294
26sulfation (GO:0051923)3.84661256
27vocalization behavior (GO:0071625)3.83309080
28positive regulation of respiratory burst (GO:0060267)3.83129095
29bicarbonate transport (GO:0015701)3.82488284
30phosphatidylinositol acyl-chain remodeling (GO:0036149)3.82257019
31drinking behavior (GO:0042756)3.76313872
32sperm capacitation (GO:0048240)3.74155241
33drug catabolic process (GO:0042737)3.73819336
34fucosylation (GO:0036065)3.72626946
35glucuronate metabolic process (GO:0019585)3.71848547
36uronic acid metabolic process (GO:0006063)3.71848547
37flavonoid metabolic process (GO:0009812)3.67140190
38bundle of His cell to Purkinje myocyte communication (GO:0086069)3.67013557
39cellular glucuronidation (GO:0052695)3.63194030
40cellular ketone body metabolic process (GO:0046950)3.61002304
41phosphatidylserine acyl-chain remodeling (GO:0036150)3.60321929
42arginine metabolic process (GO:0006525)3.59994906
43purine ribonucleoside bisphosphate metabolic process (GO:0034035)3.58876349
443-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)3.58876349
45epoxygenase P450 pathway (GO:0019373)3.55968585
46sodium ion export (GO:0071436)3.53262783
47digestion (GO:0007586)3.51163354
48ionotropic glutamate receptor signaling pathway (GO:0035235)3.49368612
49neuronal action potential propagation (GO:0019227)3.44234014
50glutamate receptor signaling pathway (GO:0007215)3.42278874
51cytidine metabolic process (GO:0046087)3.39325486
52cytidine catabolic process (GO:0006216)3.39325486
53cytidine deamination (GO:0009972)3.39325486
54kidney morphogenesis (GO:0060993)3.34258235
55regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)3.34171312
56intestinal epithelial cell development (GO:0060576)3.33806930
57water-soluble vitamin biosynthetic process (GO:0042364)3.33068493
58digestive system process (GO:0022600)3.31730910
59regulation of cGMP biosynthetic process (GO:0030826)3.30791052
60interferon-gamma secretion (GO:0072643)3.27857803
61gamma-aminobutyric acid signaling pathway (GO:0007214)3.27554150
62sialylation (GO:0097503)3.26354249
63phosphatidylglycerol acyl-chain remodeling (GO:0036148)3.24918792
64phosphatidylcholine acyl-chain remodeling (GO:0036151)3.23937979
65bile acid and bile salt transport (GO:0015721)3.23804935
66ketone body metabolic process (GO:1902224)3.23322453
67regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.22255987
68indolalkylamine metabolic process (GO:0006586)3.22249353
69positive regulation of fatty acid transport (GO:2000193)3.22129005
70synaptic transmission, glutamatergic (GO:0035249)3.20618952
71phosphatidylethanolamine acyl-chain remodeling (GO:0036152)3.20165570
72hepatocyte apoptotic process (GO:0097284)3.18576148
73keratinocyte proliferation (GO:0043616)3.18159133
74multicellular organismal movement (GO:0050879)3.17276735
75musculoskeletal movement (GO:0050881)3.17276735
76thyroid hormone metabolic process (GO:0042403)3.13229132
77quinone biosynthetic process (GO:1901663)3.13102161
78drug metabolic process (GO:0017144)3.12971750
79positive regulation of synapse maturation (GO:0090129)3.12371253
80regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)3.09431996
81endocrine process (GO:0050886)3.09431996
82regulation of systemic arterial blood pressure by hormone (GO:0001990)3.09431996
83trivalent inorganic anion homeostasis (GO:0072506)3.09335682
84phosphate ion homeostasis (GO:0055062)3.09335682
85tryptophan catabolic process (GO:0006569)3.08135747
86indole-containing compound catabolic process (GO:0042436)3.08135747
87indolalkylamine catabolic process (GO:0046218)3.08135747
88pyrimidine ribonucleoside catabolic process (GO:0046133)3.06778629
89cardiac conduction (GO:0061337)3.05546059
90DNA deamination (GO:0045006)3.05282283
91killing of cells of other organism (GO:0031640)3.04557619
92disruption of cells of other organism (GO:0044364)3.04557619
93daunorubicin metabolic process (GO:0044597)3.02671629
94polyketide metabolic process (GO:0030638)3.02671629
95doxorubicin metabolic process (GO:0044598)3.02671629
96negative regulation of hormone biosynthetic process (GO:0032353)3.01632802
97negative regulation of hormone metabolic process (GO:0032351)3.01632802
98alkaloid metabolic process (GO:0009820)3.00823156
99transepithelial transport (GO:0070633)3.00346327
100detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.97916345
101mucosal immune response (GO:0002385)2.97392801
102positive regulation of icosanoid secretion (GO:0032305)2.97259918
103regulation of heart rate by cardiac conduction (GO:0086091)2.96758861
104regulation of cGMP metabolic process (GO:0030823)2.96753742
105inositol phosphate-mediated signaling (GO:0048016)2.96296525
106vitamin biosynthetic process (GO:0009110)2.94479068
107regulation of toll-like receptor 4 signaling pathway (GO:0034143)2.92277493
108regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.90642494
109proline transport (GO:0015824)2.89248241
110nucleotide transmembrane transport (GO:1901679)2.89020409
111membrane repolarization during cardiac muscle cell action potential (GO:0086013)2.88746100
112glycerol metabolic process (GO:0006071)2.85118947
113sphingoid metabolic process (GO:0046519)2.85000628
114regulation of penile erection (GO:0060405)2.84103442
115gamma-aminobutyric acid transport (GO:0015812)2.82568913
116diol metabolic process (GO:0034311)2.82401902
117sphingosine metabolic process (GO:0006670)2.81987716
118respiratory chain complex IV assembly (GO:0008535)2.79775959
119calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)2.79694024
120regulation of cellular extravasation (GO:0002691)2.79094567
121regulation of synapse maturation (GO:0090128)2.78801488
122positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.77068320
123organ or tissue specific immune response (GO:0002251)2.77000839
124transcytosis (GO:0045056)2.74369181
125antibacterial humoral response (GO:0019731)2.74031021
126regulation of clathrin-mediated endocytosis (GO:2000369)2.73296547
127actin filament depolymerization (GO:0030042)2.73189198
128positive regulation of cGMP biosynthetic process (GO:0030828)2.73098523
129regulation of systemic arterial blood pressure (GO:0003073)2.72024143
130kynurenine metabolic process (GO:0070189)2.71565960
131negative regulation of telomere maintenance (GO:0032205)2.71208906
132auditory receptor cell stereocilium organization (GO:0060088)2.70701193
133regulation of chemokine secretion (GO:0090196)2.69849733
134positive regulation of prostaglandin secretion (GO:0032308)2.69488414
135fucose metabolic process (GO:0006004)2.69260564
136positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141)2.69193668
137regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139)2.69193668
138detection of light stimulus involved in visual perception (GO:0050908)2.68251333
139detection of light stimulus involved in sensory perception (GO:0050962)2.68251333
140negative regulation of cell fate commitment (GO:0010454)2.68121843
141organic cation transport (GO:0015695)2.67807191
142keratinocyte development (GO:0003334)2.65276969
143arginine catabolic process (GO:0006527)2.65089583
144neuron-neuron synaptic transmission (GO:0007270)2.65046972
145regulation of triglyceride catabolic process (GO:0010896)2.64974341
146drug transmembrane transport (GO:0006855)2.64179232
147positive regulation of sodium ion transmembrane transport (GO:1902307)2.63228239
148regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.62430283
149peptide hormone processing (GO:0016486)2.62037799
150positive regulation of glycoprotein biosynthetic process (GO:0010560)2.61907551
151sulfur compound transport (GO:0072348)2.61684772
152oligosaccharide biosynthetic process (GO:0009312)2.60636392
153regulation of keratinocyte proliferation (GO:0010837)2.59810241
154auditory receptor cell differentiation (GO:0042491)2.59750931
155vitamin transport (GO:0051180)2.59542636
156cobalamin metabolic process (GO:0009235)2.59236050
157tryptophan metabolic process (GO:0006568)2.59073430
158innate immune response in mucosa (GO:0002227)2.58857616
159negative regulation of synaptic transmission, GABAergic (GO:0032229)2.57498908
160epithelial structure maintenance (GO:0010669)2.56603646
161regulation of protein glycosylation (GO:0060049)2.56174894
162antimicrobial humoral response (GO:0019730)2.56034668
163fat-soluble vitamin biosynthetic process (GO:0042362)2.55889643
164photoreceptor cell maintenance (GO:0045494)2.55849943
165vitamin A metabolic process (GO:0006776)2.55780264
166protein K11-linked deubiquitination (GO:0035871)2.55281430
167relaxation of cardiac muscle (GO:0055119)2.53976008
168antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.53683711
169antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.53683711
170multicellular organismal signaling (GO:0035637)2.53173470
171protein O-linked glycosylation (GO:0006493)2.53118276
172receptor guanylyl cyclase signaling pathway (GO:0007168)2.53028885
173cytochrome complex assembly (GO:0017004)2.51826036
174antigen processing and presentation of endogenous antigen (GO:0019883)2.50967022
175membrane repolarization during action potential (GO:0086011)2.50223580
176behavioral response to ethanol (GO:0048149)2.49450642
177neutral amino acid transport (GO:0015804)2.49206045
178heme transport (GO:0015886)2.48666517
179negative regulation of protein autophosphorylation (GO:0031953)2.47306370
180primary amino compound metabolic process (GO:1901160)2.45687435
181positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.45355564
182negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.44504321
183positive regulation of sodium ion transmembrane transporter activity (GO:2000651)2.44413319
184filopodium assembly (GO:0046847)2.44121903
185chloride transmembrane transport (GO:1902476)2.43951319
186oxidative demethylation (GO:0070989)2.43508376
187decidualization (GO:0046697)2.42762913
188positive regulation of potassium ion transmembrane transport (GO:1901381)2.42285269
189membrane repolarization (GO:0086009)2.42200968
190locomotory exploration behavior (GO:0035641)2.40821839

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human5.55413490
2ZNF274_21170338_ChIP-Seq_K562_Hela3.42170882
3EZH2_22144423_ChIP-Seq_EOC_Human2.71389429
4DROSHA_22980978_ChIP-Seq_HELA_Human2.49416022
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.47769831
6CDX2_19796622_ChIP-Seq_MESCs_Mouse2.37556530
7IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.31585067
8CDX2_20551321_ChIP-Seq_CACO-2_Human2.21037181
9IKZF1_21737484_ChIP-ChIP_HCT116_Human2.09461780
10SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.08659300
11IGF1R_20145208_ChIP-Seq_DFB_Human2.08647604
12IRF8_22096565_ChIP-ChIP_GC-B_Human2.07823035
13RNF2_18974828_ChIP-Seq_MESCs_Mouse2.04032345
14EZH2_18974828_ChIP-Seq_MESCs_Mouse2.04032345
15GBX2_23144817_ChIP-Seq_PC3_Human2.02574768
16GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.95680301
17EED_16625203_ChIP-ChIP_MESCs_Mouse1.95445101
18SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.92938587
19JARID2_20075857_ChIP-Seq_MESCs_Mouse1.91669988
20FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.90277481
21CTBP1_25329375_ChIP-Seq_LNCAP_Human1.88426513
22JARID2_20064375_ChIP-Seq_MESCs_Mouse1.88051571
23SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.86778138
24SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.85535795
25EGR1_23403033_ChIP-Seq_LIVER_Mouse1.81810227
26PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.78516911
27BMI1_23680149_ChIP-Seq_NPCS_Mouse1.78434877
28* ER_23166858_ChIP-Seq_MCF-7_Human1.78309278
29TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.76577530
30BCAT_22108803_ChIP-Seq_LS180_Human1.75898170
31ZNF217_24962896_ChIP-Seq_MCF-7_Human1.74811629
32TP53_16413492_ChIP-PET_HCT116_Human1.74765395
33EZH2_27294783_Chip-Seq_ESCs_Mouse1.73063843
34EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.72689743
35SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.70898370
36MTF2_20144788_ChIP-Seq_MESCs_Mouse1.64435458
37EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.62186109
38FUS_26573619_Chip-Seq_HEK293_Human1.60262625
39ESR1_21235772_ChIP-Seq_MCF-7_Human1.59530704
40CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.56363182
41STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.54934294
42GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.54241316
43FOXA1_25329375_ChIP-Seq_VCAP_Human1.54027270
44FOXA1_27270436_Chip-Seq_PROSTATE_Human1.54027270
45RNF2_27304074_Chip-Seq_ESCs_Mouse1.53747765
46NR3C1_21868756_ChIP-Seq_MCF10A_Human1.53526843
47FOXA1_21572438_ChIP-Seq_LNCaP_Human1.53508552
48SMAD_19615063_ChIP-ChIP_OVARY_Human1.53025117
49EWS_26573619_Chip-Seq_HEK293_Human1.52733231
50SUZ12_27294783_Chip-Seq_ESCs_Mouse1.50404566
51BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.49148285
52ZFP57_27257070_Chip-Seq_ESCs_Mouse1.46477705
53ETV2_25802403_ChIP-Seq_MESCs_Mouse1.45600822
54TP53_22573176_ChIP-Seq_HFKS_Human1.43785136
55TCF4_22108803_ChIP-Seq_LS180_Human1.43643528
56IRF1_19129219_ChIP-ChIP_H3396_Human1.43598511
57TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.42653749
58PCGF2_27294783_Chip-Seq_ESCs_Mouse1.42157375
59PIAS1_25552417_ChIP-Seq_VCAP_Human1.42135105
60GATA3_21878914_ChIP-Seq_MCF-7_Human1.40091207
61TAF15_26573619_Chip-Seq_HEK293_Human1.39919963
62AR_20517297_ChIP-Seq_VCAP_Human1.39551926
63REST_21632747_ChIP-Seq_MESCs_Mouse1.39516243
64EZH2_27304074_Chip-Seq_ESCs_Mouse1.38146036
65RXR_22108803_ChIP-Seq_LS180_Human1.35807581
66IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.35226040
67CBP_20019798_ChIP-Seq_JUKART_Human1.35226040
68* SOX2_19829295_ChIP-Seq_ESCs_Human1.33831165
69* NANOG_19829295_ChIP-Seq_ESCs_Human1.33831165
70SOX2_20726797_ChIP-Seq_SW620_Human1.32444703
71FLI1_27457419_Chip-Seq_LIVER_Mouse1.32273141
72* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.28680569
73UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.28040867
74TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.27664957
75NCOR_22424771_ChIP-Seq_293T_Human1.27618352
76* TCF4_23295773_ChIP-Seq_U87_Human1.26734191
77SMAD3_21741376_ChIP-Seq_HESCs_Human1.25409875
78SUZ12_27294783_Chip-Seq_NPCs_Mouse1.25182945
79PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.24974381
80SMAD4_21799915_ChIP-Seq_A2780_Human1.24834055
81CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.24777312
82HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.21795527
83SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.21220094
84CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.21136178
85FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.21001047
86AR_21572438_ChIP-Seq_LNCaP_Human1.20957008
87AUTS2_25519132_ChIP-Seq_293T-REX_Human1.20875618
88GATA1_22025678_ChIP-Seq_K562_Human1.20139250
89PRDM14_20953172_ChIP-Seq_ESCs_Human1.19517968
90MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.18665813
91SMAD3_21741376_ChIP-Seq_EPCs_Human1.18658923
92GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.17651520
93RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.17564805
94PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.17434362
95CBX2_27304074_Chip-Seq_ESCs_Mouse1.17143813
96AR_25329375_ChIP-Seq_VCAP_Human1.16883363
97KLF5_20875108_ChIP-Seq_MESCs_Mouse1.16621840
98CTBP2_25329375_ChIP-Seq_LNCAP_Human1.16093490
99GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human1.15995563
100TP53_18474530_ChIP-ChIP_U2OS_Human1.15547741
101CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.15086959
102ERG_21242973_ChIP-ChIP_JURKAT_Human1.15029795
103MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.14690929
104HOXB7_26014856_ChIP-Seq_BT474_Human1.14689055
105GATA4_25053715_ChIP-Seq_YYC3_Human1.13148717
106* NANOG_20526341_ChIP-Seq_ESCs_Human1.13075297
107ESR2_21235772_ChIP-Seq_MCF-7_Human1.11887207
108AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.11215749
109CTNNB1_20460455_ChIP-Seq_HCT116_Human1.11018015
110MYC_19829295_ChIP-Seq_ESCs_Human1.10946468
111CRX_20693478_ChIP-Seq_RETINA_Mouse1.09918356
112KLF5_25053715_ChIP-Seq_YYC3_Human1.09092924
113* TAF2_19829295_ChIP-Seq_ESCs_Human1.08378810
114HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.07686887
115CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.06986013
116HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.06715171
117SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.05882466
118RUNX2_22187159_ChIP-Seq_PCA_Human1.05881951
119TRIM28_21343339_ChIP-Seq_HEK293_Human1.05827712
120VDR_22108803_ChIP-Seq_LS180_Human1.05504771
121SMAD4_21741376_ChIP-Seq_HESCs_Human1.05291958
122SMAD4_21741376_ChIP-Seq_EPCs_Human1.04898243
123STAT3_18555785_Chip-Seq_ESCs_Mouse1.04243119
124TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.04047526
125FOXM1_26456572_ChIP-Seq_MCF-7_Human1.03197845
126EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.02401464
127SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.02106294
128OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.01785702
129ESR1_20079471_ChIP-ChIP_T-47D_Human1.01722506
130P53_22127205_ChIP-Seq_FIBROBLAST_Human1.01232779
131NFE2_27457419_Chip-Seq_LIVER_Mouse1.00833366
132CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00406781
133FLI1_21867929_ChIP-Seq_TH2_Mouse1.00021650
134ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.00001695
135NANOG_18555785_Chip-Seq_ESCs_Mouse0.99880663
136CEBPB_22108803_ChIP-Seq_LS180_Human0.99844664
137ERA_21632823_ChIP-Seq_H3396_Human0.99587383
138AHR_22903824_ChIP-Seq_MCF-7_Human0.99485555
139SOX9_24532713_ChIP-Seq_HFSC_Mouse0.99443097
140CDX2_22108803_ChIP-Seq_LS180_Human0.98918572
141PCGF2_27294783_Chip-Seq_NPCs_Mouse0.98417433
142P300_19829295_ChIP-Seq_ESCs_Human0.98288462
143RNF2_27304074_Chip-Seq_NSC_Mouse0.98032446
144THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.98029784
145TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.97965639
146AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.97543837
147TCF4_18268006_ChIP-ChIP_LS174T_Human0.97360369
148E2F1_18555785_Chip-Seq_ESCs_Mouse0.95198839
149SUZ12_18555785_Chip-Seq_ESCs_Mouse0.93147736
150EZH2_27294783_Chip-Seq_NPCs_Mouse0.92041013
151POU3F2_20337985_ChIP-ChIP_501MEL_Human0.91774817
152EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.91582562
153TOP2B_26459242_ChIP-Seq_MCF-7_Human0.90879663
154PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.90796473
155ARNT_22903824_ChIP-Seq_MCF-7_Human0.90775325
156CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.90178747
157STAT3_23295773_ChIP-Seq_U87_Human0.89090344
158SOX2_27498859_Chip-Seq_STOMACH_Mouse0.88960181
159AR_19668381_ChIP-Seq_PC3_Human0.86615542
160PPAR_26484153_Chip-Seq_NCI-H1993_Human0.85911631
161P53_22387025_ChIP-Seq_ESCs_Mouse0.85478527

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002254_reproductive_system_inflammat3.95120144
2MP0005085_abnormal_gallbladder_physiolo3.68485278
3MP0001881_abnormal_mammary_gland3.40401970
4MP0004147_increased_porphyrin_level3.38464770
5MP0002277_abnormal_respiratory_mucosa3.32195949
6MP0009046_muscle_twitch3.32157488
7MP0003878_abnormal_ear_physiology3.32067400
8MP0005377_hearing/vestibular/ear_phenot3.32067400
9MP0004043_abnormal_pH_regulation3.06372681
10MP0010234_abnormal_vibrissa_follicle3.04972044
11MP0003866_abnormal_defecation2.99560555
12MP0002139_abnormal_hepatobiliary_system2.88934975
13MP0005365_abnormal_bile_salt2.85523586
14MP0004264_abnormal_extraembryonic_tissu2.80465806
15MP0008875_abnormal_xenobiotic_pharmacok2.73293300
16MP0005360_urolithiasis2.67430319
17MP0001666_abnormal_nutrient_absorption2.59473072
18MP0004742_abnormal_vestibular_system2.39737658
19MP0008569_lethality_at_weaning2.29054274
20MP0005310_abnormal_salivary_gland2.17711282
21MP0003195_calcinosis2.16157130
22MP0002796_impaired_skin_barrier2.11928257
23MP0001873_stomach_inflammation2.08966115
24MP0001346_abnormal_lacrimal_gland1.98768969
25MP0002138_abnormal_hepatobiliary_system1.91501679
26MP0002736_abnormal_nociception_after1.90795357
27MP0001501_abnormal_sleep_pattern1.90373565
28MP0003879_abnormal_hair_cell1.90196709
29MP0002102_abnormal_ear_morphology1.89811546
30MP0000537_abnormal_urethra_morphology1.89807786
31MP0003252_abnormal_bile_duct1.88252117
32MP0004859_abnormal_synaptic_plasticity1.87756052
33MP0008004_abnormal_stomach_pH1.86654710
34MP0005332_abnormal_amino_acid1.85975658
35MP0005551_abnormal_eye_electrophysiolog1.84428837
36MP0001440_abnormal_grooming_behavior1.81796962
37MP0001663_abnormal_digestive_system1.81236833
38MP0010329_abnormal_lipoprotein_level1.81082815
39MP0001664_abnormal_digestion1.79384588
40MP0004019_abnormal_vitamin_homeostasis1.74653513
41MP0005645_abnormal_hypothalamus_physiol1.73074359
42MP0008995_early_reproductive_senescence1.72014232
43MP0003300_gastrointestinal_ulcer1.70392726
44MP0008877_abnormal_DNA_methylation1.65187315
45MP0000569_abnormal_digit_pigmentation1.60219618
46MP0001485_abnormal_pinna_reflex1.59257013
47MP0004885_abnormal_endolymph1.57905556
48MP0002735_abnormal_chemical_nociception1.57637188
49MP0008872_abnormal_physiological_respon1.56903348
50MP0002098_abnormal_vibrissa_morphology1.54570234
51MP0001968_abnormal_touch/_nociception1.53949357
52MP0001764_abnormal_homeostasis1.52807837
53MP0000627_abnormal_mammary_gland1.52270483
54MP0002089_abnormal_postnatal_growth/wei1.49382577
55MP0005501_abnormal_skin_physiology1.49035486
56MP0003635_abnormal_synaptic_transmissio1.48402880
57MP0001986_abnormal_taste_sensitivity1.47855639
58MP0000462_abnormal_digestive_system1.45880570
59MP0003045_fibrosis1.44267622
60MP0005636_abnormal_mineral_homeostasis1.43636827
61MP0005381_digestive/alimentary_phenotyp1.41581052
62MP0000230_abnormal_systemic_arterial1.41241547
63MP0002272_abnormal_nervous_system1.40566622
64MP0002557_abnormal_social/conspecific_i1.39906919
65MP0002067_abnormal_sensory_capabilities1.38320009
66MP0009379_abnormal_foot_pigmentation1.36546758
67MP0009643_abnormal_urine_homeostasis1.36494092
68MP0003806_abnormal_nucleotide_metabolis1.33775744
69MP0000538_abnormal_urinary_bladder1.33599599
70MP0002734_abnormal_mechanical_nocicepti1.33309819
71MP0003453_abnormal_keratinocyte_physiol1.30941818
72MP0002837_dystrophic_cardiac_calcinosis1.28967888
73MP0000490_abnormal_crypts_of1.26731948
74MP0003183_abnormal_peptide_metabolism1.26245206
75MP0004145_abnormal_muscle_electrophysio1.25424720
76MP0010155_abnormal_intestine_physiology1.25068060
77MP0003724_increased_susceptibility_to1.24030840
78MP0010678_abnormal_skin_adnexa1.23546778
79MP0003787_abnormal_imprinting1.23371788
80MP0006072_abnormal_retinal_apoptosis1.22874470
81MP0009745_abnormal_behavioral_response1.21411787
82MP0010386_abnormal_urinary_bladder1.21219152
83MP0002572_abnormal_emotion/affect_behav1.20312140
84MP0005174_abnormal_tail_pigmentation1.16674459
85MP0003011_delayed_dark_adaptation1.14731423
86MP0003941_abnormal_skin_development1.12553412
87MP0009764_decreased_sensitivity_to1.11241244
88MP0000383_abnormal_hair_follicle1.10849681
89MP0004270_analgesia1.10030775
90MP0001486_abnormal_startle_reflex1.09798748
91MP0001756_abnormal_urination1.09453738
92MP0010771_integument_phenotype1.09122348
93MP0008775_abnormal_heart_ventricle1.06707622
94MP0003880_abnormal_central_pattern1.06309619
95MP0004484_altered_response_of1.04885644
96MP0001919_abnormal_reproductive_system1.04684603
97MP0002184_abnormal_innervation1.02056041
98MP0000566_synostosis1.02003722
99MP0002938_white_spotting1.01946864
100MP0003868_abnormal_feces_composition1.01310991
101MP0000427_abnormal_hair_cycle0.99574822
102MP0002733_abnormal_thermal_nociception0.99311696
103MP0002064_seizures0.98604171
104MP0005389_reproductive_system_phenotype0.98474016
105MP0003315_abnormal_perineum_morphology0.96883126
106MP0001216_abnormal_epidermal_layer0.96500807
107MP0000477_abnormal_intestine_morphology0.96013883
108MP0004782_abnormal_surfactant_physiolog0.95306627
109MP0002136_abnormal_kidney_physiology0.94386598
110MP0005253_abnormal_eye_physiology0.94277586
111MP0000470_abnormal_stomach_morphology0.93301140
112MP0002118_abnormal_lipid_homeostasis0.93220272
113MP0004142_abnormal_muscle_tone0.93032610
114MP0002876_abnormal_thyroid_physiology0.91455832
115MP0005671_abnormal_response_to0.90431139
116MP0005423_abnormal_somatic_nervous0.87162095
117MP0002163_abnormal_gland_morphology0.86220036
118MP0002063_abnormal_learning/memory/cond0.84750038
119MP0004215_abnormal_myocardial_fiber0.83326630
120MP0004924_abnormal_behavior0.82709629
121MP0005386_behavior/neurological_phenoty0.82709629
122MP0005084_abnormal_gallbladder_morpholo0.82657462
123MP0001905_abnormal_dopamine_level0.82422985
124MP0001188_hyperpigmentation0.81872665
125MP0005171_absent_coat_pigmentation0.81851501
126MP0005646_abnormal_pituitary_gland0.81009279
127MP0003646_muscle_fatigue0.80424400
128MP0003936_abnormal_reproductive_system0.80363027
129MP0005670_abnormal_white_adipose0.79749662
130MP0001765_abnormal_ion_homeostasis0.78977456
131MP0003656_abnormal_erythrocyte_physiolo0.78219171
132MP0009840_abnormal_foam_cell0.78099953
133MP0002693_abnormal_pancreas_physiology0.76843685
134MP0006276_abnormal_autonomic_nervous0.76808726
135MP0001970_abnormal_pain_threshold0.76526163
136MP0001502_abnormal_circadian_rhythm0.76443883
137MP0002160_abnormal_reproductive_system0.76179711
138MP0005535_abnormal_body_temperature0.76038118
139MP0004947_skin_inflammation0.74459398
140MP0000631_abnormal_neuroendocrine_gland0.74316628
141MP0009785_altered_susceptibility_to0.74236416
142MP0002909_abnormal_adrenal_gland0.74097209
143MP0003953_abnormal_hormone_level0.73961211
144MP0000467_abnormal_esophagus_morphology0.72282718
145MP0002148_abnormal_hypersensitivity_rea0.72082141
146MP0002638_abnormal_pupillary_reflex0.71638394
147MP0005448_abnormal_energy_balance0.67656229
148MP0003950_abnormal_plasma_membrane0.67266290
149MP0002060_abnormal_skin_morphology0.66569257
150MP0001984_abnormal_olfaction0.66244238
151MP0003718_maternal_effect0.65405219
152MP0004858_abnormal_nervous_system0.63034037
153MP0005083_abnormal_biliary_tract0.62595216
154MP0000026_abnormal_inner_ear0.60836070

Predicted human phenotypes

RankGene SetZ-score
1Onycholysis (HP:0001806)5.75173982
2Progressive cerebellar ataxia (HP:0002073)5.00020288
3Decreased circulating renin level (HP:0003351)4.60747127
4Scanning speech (HP:0002168)4.07807052
5Febrile seizures (HP:0002373)3.95054818
6Right ventricular cardiomyopathy (HP:0011663)3.87401493
7Action tremor (HP:0002345)3.83281851
8Gaze-evoked nystagmus (HP:0000640)3.71989764
9Ileus (HP:0002595)3.71229332
10Milia (HP:0001056)3.69061604
11Abnormality of renin-angiotensin system (HP:0000847)3.55660440
12Curly hair (HP:0002212)3.51872555
13Focal motor seizures (HP:0011153)3.51164155
14Congenital stationary night blindness (HP:0007642)3.49165878
15Pancreatic cysts (HP:0001737)3.42961744
16Fragile nails (HP:0001808)3.40355790
17Abnormality of vitamin B metabolism (HP:0004340)3.37457236
18Cheilitis (HP:0100825)3.36133577
19Pili torti (HP:0003777)3.28845848
20Hyperactive renin-angiotensin system (HP:0000841)3.27936211
21Congenital sensorineural hearing impairment (HP:0008527)3.27193893
22Abnormality of the renal cortex (HP:0011035)3.26042688
23Abnormality of the vitamin B12 metabolism (HP:0004341)3.25384476
24Plantar hyperkeratosis (HP:0007556)3.24410290
25Abnormality of midbrain morphology (HP:0002418)3.19772161
26Molar tooth sign on MRI (HP:0002419)3.19772161
27Alopecia of scalp (HP:0002293)3.10830111
28Epileptic encephalopathy (HP:0200134)3.07491151
29Alkalosis (HP:0001948)3.06205211
30Widely patent fontanelles and sutures (HP:0004492)3.04242383
31Hyperventilation (HP:0002883)3.00580510
32Optic neuritis (HP:0100653)2.99139054
33Retrobulbar optic neuritis (HP:0100654)2.99139054
34Atrophic scars (HP:0001075)2.98675138
35Aplasia cutis congenita (HP:0001057)2.98042501
36Amelogenesis imperfecta (HP:0000705)2.93739197
37Poikilocytosis (HP:0004447)2.92286108
38Acanthocytosis (HP:0001927)2.90276977
39Hydroxyprolinuria (HP:0003080)2.89219972
40Abnormality of proline metabolism (HP:0010907)2.89219972
41Type II lissencephaly (HP:0007260)2.87873137
42Abolished electroretinogram (ERG) (HP:0000550)2.87022292
43True hermaphroditism (HP:0010459)2.86222853
44Parakeratosis (HP:0001036)2.85141653
45Hyperglycinuria (HP:0003108)2.84790749
46Ventricular fibrillation (HP:0001663)2.83492183
47Pancreatic fibrosis (HP:0100732)2.82587096
48Stomach cancer (HP:0012126)2.77462981
49Glycosuria (HP:0003076)2.74182431
50Abnormality of urine glucose concentration (HP:0011016)2.74182431
51Hypoplasia of dental enamel (HP:0006297)2.71449278
52Dysmetric saccades (HP:0000641)2.69151989
53Pustule (HP:0200039)2.66913511
54Choroideremia (HP:0001139)2.65953201
55Split foot (HP:0001839)2.65472531
56Hyperphosphatemia (HP:0002905)2.61076480
57Genetic anticipation (HP:0003743)2.60377960
58Ectropion (HP:0000656)2.59969680
59Oligodactyly (hands) (HP:0001180)2.59782269
60Nephronophthisis (HP:0000090)2.58698625
61Abnormality of glutamine family amino acid metabolism (HP:0010902)2.58698016
62Abnormal blistering of the skin (HP:0008066)2.58383352
63Decreased electroretinogram (ERG) amplitude (HP:0000654)2.57497400
64Orchitis (HP:0100796)2.57488241
65Hemiplegia (HP:0002301)2.55318872
66Prostate neoplasm (HP:0100787)2.55230901
67Atonic seizures (HP:0010819)2.54496473
68Tubular atrophy (HP:0000092)2.53820307
69Premature loss of primary teeth (HP:0006323)2.52207297
70Horizontal nystagmus (HP:0000666)2.50894071
71Hyperaldosteronism (HP:0000859)2.50760947
72Syncope (HP:0001279)2.49291127
73Abnormality of serine family amino acid metabolism (HP:0010894)2.47858649
74Abnormality of glycine metabolism (HP:0010895)2.47858649
75Myositis (HP:0100614)2.47625115
76Abnormality of the renal medulla (HP:0100957)2.47356482
77Congenital, generalized hypertrichosis (HP:0004540)2.45612148
78Attenuation of retinal blood vessels (HP:0007843)2.43745203
79Renal cortical cysts (HP:0000803)2.40165310
80Polydipsia (HP:0001959)2.38920842
81Abnormal drinking behavior (HP:0030082)2.38920842
82Malnutrition (HP:0004395)2.34291255
83Abnormality of vitamin metabolism (HP:0100508)2.34180817
84Confusion (HP:0001289)2.33492338
85Vascular calcification (HP:0004934)2.33481392
86Broad-based gait (HP:0002136)2.31888710
87Chronic hepatic failure (HP:0100626)2.31341067
88Congenital ichthyosiform erythroderma (HP:0007431)2.30955362
89Large for gestational age (HP:0001520)2.29003985
90Nail dystrophy (HP:0008404)2.28554502
91Micronodular cirrhosis (HP:0001413)2.26719182
92Focal seizures (HP:0007359)2.23657416
93Abnormality of magnesium homeostasis (HP:0004921)2.22452134
94Hypomagnesemia (HP:0002917)2.21275342
95Methylmalonic aciduria (HP:0012120)2.18896570
96Abnormality of chloride homeostasis (HP:0011422)2.18481980
97Hypothermia (HP:0002045)2.18068966
98Chronic diarrhea (HP:0002028)2.15238112
99Hypohidrosis (HP:0000966)2.13854850
100Chromosomal breakage induced by crosslinking agents (HP:0003221)2.11717016
101Autoimmune hemolytic anemia (HP:0001890)2.11384749
102Ketosis (HP:0001946)2.10902759
103Hypokalemia (HP:0002900)2.10638380
104Dehydration (HP:0001944)2.09929519
105Decreased central vision (HP:0007663)2.09926833
106White forelock (HP:0002211)2.09146642
107Ketoacidosis (HP:0001993)2.07531071
108Hypobetalipoproteinemia (HP:0003563)2.06985636
109Chorioretinal atrophy (HP:0000533)2.06709849
110Chronic otitis media (HP:0000389)2.04463733
111Hypoalbuminemia (HP:0003073)2.01266674
112Abnormal albumin level (HP:0012116)2.01266674
113Dysdiadochokinesis (HP:0002075)2.00865852
114Fat malabsorption (HP:0002630)2.00607458
115Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.00218758
116Abnormality of alanine metabolism (HP:0010916)2.00218758
117Hyperalaninemia (HP:0003348)2.00218758
118Barrel-shaped chest (HP:0001552)1.99542283
119Cystic liver disease (HP:0006706)1.98141763
120Abnormality of renal excretion (HP:0011036)1.98099844
121Lethargy (HP:0001254)1.96436558
122Abnormality of the pons (HP:0007361)1.95749977
123Abnormality of purine metabolism (HP:0004352)1.95653730
124Rectal prolapse (HP:0002035)1.95647310
125Unilateral renal agenesis (HP:0000122)1.95372962
126Metabolic acidosis (HP:0001942)1.95208441
127Potter facies (HP:0002009)1.95138589
128Facial shape deformation (HP:0011334)1.95138589
129Intention tremor (HP:0002080)1.94724259
130Abnormal urine output (HP:0012590)1.94697162
131Abnormal biliary tract morphology (HP:0012440)1.94487151
132Medial flaring of the eyebrow (HP:0010747)1.94221064
133Esophageal atresia (HP:0002032)1.93779749
134Blepharitis (HP:0000498)1.93604635
135Inability to walk (HP:0002540)1.92243297
136Polyuria (HP:0000103)1.91335344
137Cardiovascular calcification (HP:0011915)1.91123794
138Abnormality of dicarboxylic acid metabolism (HP:0010995)1.90711868
139Dicarboxylic aciduria (HP:0003215)1.90711868
140Hypoplasia of the pons (HP:0012110)1.89565017
141Chromsome breakage (HP:0040012)1.88981278
142Abnormal rod and cone electroretinograms (HP:0008323)1.88874338
143Abnormality of aspartate family amino acid metabolism (HP:0010899)1.88416220
144Abnormality of potassium homeostasis (HP:0011042)1.87562609
145Progressive inability to walk (HP:0002505)1.86623352
146Bundle branch block (HP:0011710)1.86581840
147Thin bony cortex (HP:0002753)1.85960074
148Furrowed tongue (HP:0000221)1.85937157
149Conjugated hyperbilirubinemia (HP:0002908)1.85818092
150Cerebellar dysplasia (HP:0007033)1.85120293
151Impaired smooth pursuit (HP:0007772)1.84706603
152Pigmentary retinal degeneration (HP:0001146)1.83202866
153Nonprogressive disorder (HP:0003680)1.82540044
154Absence seizures (HP:0002121)1.81600322
155Corneal erosion (HP:0200020)1.80336727
156Dynein arm defect of respiratory motile cilia (HP:0012255)1.79904275
157Absent/shortened dynein arms (HP:0200106)1.79904275
158Severe muscular hypotonia (HP:0006829)1.79704615
159Fragile skin (HP:0001030)1.79401902
160Abnormality of dental color (HP:0011073)1.79227650
161Ridged nail (HP:0001807)1.79124958
162Pendular nystagmus (HP:0012043)1.78600719
163Abnormality of B cell number (HP:0010975)1.78343160
164B lymphocytopenia (HP:0010976)1.78343160
165Keratoconjunctivitis (HP:0001096)1.77628347
166Proximal tubulopathy (HP:0000114)1.76919381
167Hepatic necrosis (HP:0002605)1.76057674
168Pancreatitis (HP:0001733)1.75161341
169Woolly hair (HP:0002224)1.73486694
170Abnormality of calcium-phosphate metabolism (HP:0100530)1.73363809
171Abnormality of the nasal septum (HP:0000419)1.72175906
172Metabolic alkalosis (HP:0200114)1.72058778
173Ureteral stenosis (HP:0000071)1.71436994
174Patchy hypopigmentation of hair (HP:0011365)1.71086306
175Diplopia (HP:0000651)1.70717999
176Abnormality of binocular vision (HP:0011514)1.70717999
177Aplasia/Hypoplasia of the tibia (HP:0005772)1.70541338
178Bile duct proliferation (HP:0001408)1.70253320
179Abnormal biliary tract physiology (HP:0012439)1.70253320
180Abnormality of macular pigmentation (HP:0008002)1.70215887
181Methylmalonic acidemia (HP:0002912)1.69001518
182Popliteal pterygium (HP:0009756)1.68758167
183Reticulocytosis (HP:0001923)1.68634480
184Lissencephaly (HP:0001339)1.66942216
185Tetany (HP:0001281)1.66918366
186Stomatitis (HP:0010280)1.65641673
187Abnormality of serum amino acid levels (HP:0003112)1.62177726
188Cerebral palsy (HP:0100021)1.61982741

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA25.50851260
2ACVR1B4.91204417
3RIPK14.20491222
4SIK33.25927677
5MST43.01508561
6FRK2.96533309
7WNK42.75725660
8LMTK22.74269572
9STK392.59929915
10WNK32.58933442
11IRAK32.50113727
12PRPF4B2.49771020
13MAP4K22.43614096
14TNIK2.38539993
15BMPR1B2.37975730
16TLK12.37028165
17CASK2.29540788
18PINK12.27826637
19STK382.26006925
20FER2.23701994
21LATS12.16923292
22PTK62.06729751
23AKT32.03540258
24TAOK31.98167327
25CAMKK21.91833235
26EPHB21.81712638
27INSRR1.77714023
28SIK11.68726803
29NTRK31.63399650
30MST1R1.59938164
31TNK21.58565751
32IKBKE1.57234773
33DAPK21.57060230
34NUAK11.55941874
35NME11.54834561
36WNK11.46695684
37SGK21.29461095
38MAPK131.23862236
39MAP3K121.23648486
40CDK191.21768293
41PTK21.20696266
42BMPR21.14460686
43TXK1.11849047
44EPHB11.10588383
45MAP3K141.06163256
46ADRBK11.05159890
47STK38L1.02200115
48SGK31.01746494
49PRKG21.00569234
50PAK30.97638417
51CAMK10.97393103
52CAMK2G0.96956499
53EPHA30.92400102
54MAP3K40.91347403
55YES10.89822711
56SGK4940.88906955
57SGK2230.88906955
58FGFR20.85652028
59IRAK10.85645785
60SIK20.84854009
61MKNK20.83664360
62MAPKAPK50.78712452
63RPS6KB20.77999009
64BCR0.77782397
65EIF2AK20.77379426
66BCKDK0.75905614
67MAPKAPK30.73029988
68ERBB30.70888424
69ZAK0.70645097
70CAMKK10.66849719
71PTK2B0.65627431
72DYRK20.65312181
73CDK30.64903283
74CAMK2B0.64788636
75DMPK0.64590528
76EIF2AK30.64425816
77KIT0.63015089
78MAP2K60.62786549
79PRKCQ0.62339218
80TIE10.61682102
81TEC0.61295960
82MET0.61113264
83RIPK40.60638696
84GRK10.60311453
85PHKG10.60179751
86PHKG20.60179751
87BRSK20.59882900
88ADRBK20.59487383
89NLK0.58751500
90PRKCI0.58617981
91MAP3K90.58493086
92PIK3CA0.58353435
93EPHA40.56682811
94TRIM280.54276696
95STK100.52493779
96CDK80.51076583
97PRKG10.50824068
98TAOK20.50500398
99PRKCZ0.50117538
100CAMK1G0.50113997
101TGFBR10.49761921
102MAP4K10.49554095
103PRKCE0.49467955
104TBK10.49407111
105MAP2K20.49090392
106ERBB20.48481842
107JAK10.48466554
108CAMK2D0.47541749
109CHUK0.47051080
110GRK60.46374788
111PAK40.44732977
112CSNK1G20.44510280
113MAP2K10.43709350
114CSNK1G30.42702046
115SYK0.42044746
116OXSR10.42036372
117PRKACA0.41842147
118STK30.41840886
119CSNK1G10.41826178
120MATK0.41555321
121MAPK110.41232629
122PRKAA20.41012646
123PDK20.40933108
124IRAK40.40721790
125MAP2K70.39505884
126IGF1R0.39102315
127CDC42BPA0.38497170
128TRPM70.38087174
129PRKCA0.37344012
130SRC0.36955347
131ITK0.35805242
132RPS6KB10.34757629
133PRKACG0.34701327
134CSNK1A10.34535556
135IKBKB0.34514648
136MAPK150.34283356
137PLK20.33405709
138LYN0.33354348
139PRKAA10.32803319
140RPS6KA50.32198190
141PIM20.30443142
142NEK60.29279403
143MAP3K70.29058648
144MAP3K20.28654962
145GRK50.28352058
146MKNK10.28019490
147CSK0.27682158
148STK240.26666236
149PRKCG0.26009271
150SGK10.25941566
151STK110.25620423
152CAMK2A0.25151881
153MARK30.24756849
154PIM10.24404999
155MUSK0.23873795

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.81989859
2Mineral absorption_Homo sapiens_hsa049783.32704894
3Fatty acid biosynthesis_Homo sapiens_hsa000612.78405593
4Fat digestion and absorption_Homo sapiens_hsa049752.75222816
5Nitrogen metabolism_Homo sapiens_hsa009102.57772419
6Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005122.53456447
7Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.46207442
8Maturity onset diabetes of the young_Homo sapiens_hsa049502.41834275
9Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.34073800
10Taste transduction_Homo sapiens_hsa047422.32736152
11Glutamatergic synapse_Homo sapiens_hsa047242.20016222
12Sulfur metabolism_Homo sapiens_hsa009202.18861257
13Tryptophan metabolism_Homo sapiens_hsa003802.04941461
14Long-term depression_Homo sapiens_hsa047301.97117797
15Salivary secretion_Homo sapiens_hsa049701.93284940
16Caffeine metabolism_Homo sapiens_hsa002321.91493400
17Pentose and glucuronate interconversions_Homo sapiens_hsa000401.83595369
18Histidine metabolism_Homo sapiens_hsa003401.82070620
19Chemical carcinogenesis_Homo sapiens_hsa052041.81418353
20Retinol metabolism_Homo sapiens_hsa008301.77836781
21Morphine addiction_Homo sapiens_hsa050321.77001537
22Circadian entrainment_Homo sapiens_hsa047131.73941892
23Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.70722498
24Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.70533724
25Asthma_Homo sapiens_hsa053101.68920579
26Steroid hormone biosynthesis_Homo sapiens_hsa001401.65851601
27Butanoate metabolism_Homo sapiens_hsa006501.65398354
28Renin-angiotensin system_Homo sapiens_hsa046141.61241165
29Synaptic vesicle cycle_Homo sapiens_hsa047211.61024074
30Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.59860979
31Phosphatidylinositol signaling system_Homo sapiens_hsa040701.59425214
32Vitamin digestion and absorption_Homo sapiens_hsa049771.59199094
33Gastric acid secretion_Homo sapiens_hsa049711.59167203
34Pancreatic secretion_Homo sapiens_hsa049721.58529626
35Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.56764147
36Long-term potentiation_Homo sapiens_hsa047201.56655945
37GABAergic synapse_Homo sapiens_hsa047271.54601000
38alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.52976752
39Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.45771975
40Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.45290027
41Thyroid hormone synthesis_Homo sapiens_hsa049181.35618400
42Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.32637266
43Protein digestion and absorption_Homo sapiens_hsa049741.29641600
44Drug metabolism - other enzymes_Homo sapiens_hsa009831.28073123
45Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.22568532
46Carbohydrate digestion and absorption_Homo sapiens_hsa049731.21970701
47Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.21621192
48Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.20307914
49Galactose metabolism_Homo sapiens_hsa000521.19148666
50Selenocompound metabolism_Homo sapiens_hsa004501.19134891
51Peroxisome_Homo sapiens_hsa041461.17967729
52Fatty acid degradation_Homo sapiens_hsa000711.17121575
53Type I diabetes mellitus_Homo sapiens_hsa049401.15347192
54Allograft rejection_Homo sapiens_hsa053301.14297750
55Sphingolipid metabolism_Homo sapiens_hsa006001.13248029
56Insulin secretion_Homo sapiens_hsa049111.13238035
57Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.11826977
58Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.11523924
59Intestinal immune network for IgA production_Homo sapiens_hsa046721.11005389
60Graft-versus-host disease_Homo sapiens_hsa053321.09289505
61Linoleic acid metabolism_Homo sapiens_hsa005911.09120243
62Autoimmune thyroid disease_Homo sapiens_hsa053201.08438711
63Propanoate metabolism_Homo sapiens_hsa006401.07960095
64Calcium signaling pathway_Homo sapiens_hsa040201.07396110
65Serotonergic synapse_Homo sapiens_hsa047261.07226689
66Arachidonic acid metabolism_Homo sapiens_hsa005901.07174678
67Arginine biosynthesis_Homo sapiens_hsa002201.05968215
68Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.03037765
69Inositol phosphate metabolism_Homo sapiens_hsa005620.98137040
70Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.97195033
71Collecting duct acid secretion_Homo sapiens_hsa049660.96915518
72Oxidative phosphorylation_Homo sapiens_hsa001900.95158845
73Bile secretion_Homo sapiens_hsa049760.95046786
74Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.94246154
75Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.92560205
76Amphetamine addiction_Homo sapiens_hsa050310.90843355
77Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.89655557
78Arginine and proline metabolism_Homo sapiens_hsa003300.88802423
79Aldosterone synthesis and secretion_Homo sapiens_hsa049250.88744121
80Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.88610087
81Cholinergic synapse_Homo sapiens_hsa047250.85069308
82Hematopoietic cell lineage_Homo sapiens_hsa046400.84671189
83cAMP signaling pathway_Homo sapiens_hsa040240.82411462
84Olfactory transduction_Homo sapiens_hsa047400.81646390
85Tight junction_Homo sapiens_hsa045300.81597317
86Circadian rhythm_Homo sapiens_hsa047100.80244927
87Prolactin signaling pathway_Homo sapiens_hsa049170.79644074
88ABC transporters_Homo sapiens_hsa020100.79327050
89Dopaminergic synapse_Homo sapiens_hsa047280.79106030
90Vibrio cholerae infection_Homo sapiens_hsa051100.77634156
91Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.77233813
92Protein export_Homo sapiens_hsa030600.73180674
93African trypanosomiasis_Homo sapiens_hsa051430.72163197
94Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.72149358
95Primary bile acid biosynthesis_Homo sapiens_hsa001200.72038132
96Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.71362976
97Type II diabetes mellitus_Homo sapiens_hsa049300.69576807
98Sulfur relay system_Homo sapiens_hsa041220.68696397
99Cyanoamino acid metabolism_Homo sapiens_hsa004600.68320929
100GnRH signaling pathway_Homo sapiens_hsa049120.67183676
101Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.66144756
102Renin secretion_Homo sapiens_hsa049240.65914704
103Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.64794332
104Fructose and mannose metabolism_Homo sapiens_hsa000510.63958108
105Hepatitis C_Homo sapiens_hsa051600.63494058
106Ether lipid metabolism_Homo sapiens_hsa005650.60193887
107Glutathione metabolism_Homo sapiens_hsa004800.59776554
108Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.59513011
109Leukocyte transendothelial migration_Homo sapiens_hsa046700.58503443
110Parkinsons disease_Homo sapiens_hsa050120.56895383
111Estrogen signaling pathway_Homo sapiens_hsa049150.53320933
112Metabolic pathways_Homo sapiens_hsa011000.52920528
113Ovarian steroidogenesis_Homo sapiens_hsa049130.52908495
114Glycerophospholipid metabolism_Homo sapiens_hsa005640.52903240
115Glycerolipid metabolism_Homo sapiens_hsa005610.51541266
116beta-Alanine metabolism_Homo sapiens_hsa004100.51006350
117Fatty acid metabolism_Homo sapiens_hsa012120.49449507
118Choline metabolism in cancer_Homo sapiens_hsa052310.49434972
119Oxytocin signaling pathway_Homo sapiens_hsa049210.48457698
120ErbB signaling pathway_Homo sapiens_hsa040120.48071873
121Vascular smooth muscle contraction_Homo sapiens_hsa042700.46651675
122Staphylococcus aureus infection_Homo sapiens_hsa051500.45081547
123Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.42196515
124Endometrial cancer_Homo sapiens_hsa052130.41597021
125Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.40481683
126Dorso-ventral axis formation_Homo sapiens_hsa043200.40368482
127Phototransduction_Homo sapiens_hsa047440.39825138
128PPAR signaling pathway_Homo sapiens_hsa033200.37738735
129Chemokine signaling pathway_Homo sapiens_hsa040620.37044456
130SNARE interactions in vesicular transport_Homo sapiens_hsa041300.36842168
131Jak-STAT signaling pathway_Homo sapiens_hsa046300.35756089
132Starch and sucrose metabolism_Homo sapiens_hsa005000.35358869
133Rheumatoid arthritis_Homo sapiens_hsa053230.35188551
134Folate biosynthesis_Homo sapiens_hsa007900.34414622
135cGMP-PKG signaling pathway_Homo sapiens_hsa040220.34341685
136Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.34311377
137Antigen processing and presentation_Homo sapiens_hsa046120.34205552
138Primary immunodeficiency_Homo sapiens_hsa053400.34166820
139Melanogenesis_Homo sapiens_hsa049160.33728644
140Regulation of autophagy_Homo sapiens_hsa041400.33549439
141Axon guidance_Homo sapiens_hsa043600.32572199
142Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.32268197
143Gap junction_Homo sapiens_hsa045400.31832914
144Alzheimers disease_Homo sapiens_hsa050100.29334127
145Basal transcription factors_Homo sapiens_hsa030220.28999937
146Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.28173185
147Fatty acid elongation_Homo sapiens_hsa000620.24869224
148Homologous recombination_Homo sapiens_hsa034400.23781550
149Huntingtons disease_Homo sapiens_hsa050160.23001879
150Tyrosine metabolism_Homo sapiens_hsa003500.22298658

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