BCL9L

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein heterotrimerization (GO:0070208)4.01313328
2positive regulation of fatty acid beta-oxidation (GO:0032000)3.97796848
3regulation of fatty acid beta-oxidation (GO:0031998)3.81363850
4regulation of extracellular matrix disassembly (GO:0010715)3.72470872
5regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.61426772
6skin morphogenesis (GO:0043589)3.61282774
7Golgi transport vesicle coating (GO:0048200)3.49892755
8COPI coating of Golgi vesicle (GO:0048205)3.49892755
9insulin-like growth factor receptor signaling pathway (GO:0048009)3.44914714
10plasma membrane repair (GO:0001778)3.43496334
11atrioventricular valve morphogenesis (GO:0003181)3.42675232
12planar cell polarity pathway involved in neural tube closure (GO:0090179)3.38457114
13positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.37077066
14regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.36904361
15regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.33532956
16positive regulation of Cdc42 GTPase activity (GO:0043089)3.29430788
17positive regulation of histone deacetylation (GO:0031065)3.29327187
18activation of Rac GTPase activity (GO:0032863)3.28166919
19negative regulation of fatty acid transport (GO:2000192)3.26996141
20regulation of cholesterol homeostasis (GO:2000188)3.25888635
21cell-substrate junction assembly (GO:0007044)3.21636738
22positive regulation of fatty acid oxidation (GO:0046321)3.19991111
23regulation of histone H3-K27 methylation (GO:0061085)3.19234684
24alpha-linolenic acid metabolic process (GO:0036109)3.18487350
25positive regulation of glycogen biosynthetic process (GO:0045725)3.15448030
26cytoskeletal anchoring at plasma membrane (GO:0007016)3.13068116
27endodermal cell differentiation (GO:0035987)3.09925118
28embryonic process involved in female pregnancy (GO:0060136)3.07514370
29adherens junction assembly (GO:0034333)3.07506128
30dichotomous subdivision of an epithelial terminal unit (GO:0060600)3.05346801
31negative regulation of cell size (GO:0045792)3.02118459
32hemidesmosome assembly (GO:0031581)3.02110510
33collagen fibril organization (GO:0030199)3.01486552
34branching involved in mammary gland duct morphogenesis (GO:0060444)2.98660926
35apoptotic process involved in morphogenesis (GO:0060561)2.97970141
36epithelial cell-cell adhesion (GO:0090136)2.95331470
37basement membrane organization (GO:0071711)2.95021598
38regulation of glucose import in response to insulin stimulus (GO:2001273)2.89699804
39regulation of fatty acid oxidation (GO:0046320)2.89105529
40positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.88038224
41mannose metabolic process (GO:0006013)2.87662930
42hippo signaling (GO:0035329)2.87219400
43embryonic retina morphogenesis in camera-type eye (GO:0060059)2.82924886
44positive regulation of keratinocyte differentiation (GO:0045618)2.82496429
45cell-substrate adherens junction assembly (GO:0007045)2.82251567
46focal adhesion assembly (GO:0048041)2.82251567
47desmosome organization (GO:0002934)2.81743508
48bone trabecula formation (GO:0060346)2.81720899
49cardiac myofibril assembly (GO:0055003)2.80072161
50negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067)2.78770849
51positive regulation of glycogen metabolic process (GO:0070875)2.77750160
52negative regulation of erythrocyte differentiation (GO:0045647)2.75677391
53negative regulation of fibrinolysis (GO:0051918)2.75511770
54epoxygenase P450 pathway (GO:0019373)2.75415722
55regulation of early endosome to late endosome transport (GO:2000641)2.75035656
56stress fiber assembly (GO:0043149)2.73487996
57apoptotic cell clearance (GO:0043277)2.72879003
58endothelial cell chemotaxis (GO:0035767)2.72492956
59embryonic eye morphogenesis (GO:0048048)2.71691043
60neuron projection extension involved in neuron projection guidance (GO:1902284)2.68752305
61axon extension involved in axon guidance (GO:0048846)2.68752305
62vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.68582815
63regulation of endothelial cell chemotaxis (GO:2001026)2.68275140
64regulation of NFAT protein import into nucleus (GO:0051532)2.67839396
65regulation of extracellular matrix organization (GO:1903053)2.64799366
66positive regulation of extracellular matrix organization (GO:1903055)2.64055201
67cell migration involved in sprouting angiogenesis (GO:0002042)2.63261907
68positive regulation of receptor recycling (GO:0001921)2.62558306
69regulation of tight junction assembly (GO:2000810)2.62331652
70regulation of water loss via skin (GO:0033561)2.62027749
71maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.61495995
72thymic T cell selection (GO:0045061)2.60527110
73regulation of hippo signaling (GO:0035330)2.58815864
74negative regulation of catenin import into nucleus (GO:0035414)2.58206576
75blood vessel endothelial cell migration (GO:0043534)2.57932231
76protein retention in ER lumen (GO:0006621)2.56077174
77retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.55587944
78ear development (GO:0043583)2.55382165
79vascular endothelial growth factor signaling pathway (GO:0038084)2.55157378
80barbed-end actin filament capping (GO:0051016)2.54095254
81mammary gland epithelial cell proliferation (GO:0033598)2.52489804
82positive regulation of lipid catabolic process (GO:0050996)2.52444832
83signal complex assembly (GO:0007172)2.52367312
84hypotonic response (GO:0006971)2.51804323
85negative regulation of viral release from host cell (GO:1902187)2.51532905
86low-density lipoprotein particle clearance (GO:0034383)2.50570459
87polarized epithelial cell differentiation (GO:0030859)2.48745208
88endocytic recycling (GO:0032456)2.48121224
89growth hormone receptor signaling pathway (GO:0060396)2.45301417
90negative regulation of heart growth (GO:0061117)2.43158702
91negative regulation of cardiac muscle tissue growth (GO:0055022)2.43158702
92cell-cell junction maintenance (GO:0045217)2.43012641
93response to water (GO:0009415)2.42476218
94cardiac muscle cell proliferation (GO:0060038)2.40268788
95branching involved in salivary gland morphogenesis (GO:0060445)2.39930166
96positive regulation of triglyceride biosynthetic process (GO:0010867)2.39070201
97anatomical structure regression (GO:0060033)2.38944393
98cell adhesion mediated by integrin (GO:0033627)2.37784579
99carnitine shuttle (GO:0006853)2.37160525
100cellular response to epidermal growth factor stimulus (GO:0071364)2.37098950
101substrate-dependent cell migration (GO:0006929)2.37064217
102cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.36341882
103negative regulation of lipid transport (GO:0032369)2.35720033
104establishment of apical/basal cell polarity (GO:0035089)2.35140844
105membrane protein ectodomain proteolysis (GO:0006509)2.35018220
106modulation by symbiont of host cellular process (GO:0044068)2.33924629
107modulation by virus of host morphology or physiology (GO:0019048)2.33782103
108cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.33549963
109positive regulation of endothelial cell migration (GO:0010595)2.33478509
110fatty acid transmembrane transport (GO:1902001)2.32137878
111response to fluid shear stress (GO:0034405)2.31632815
112regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.31380455
113histone H3-K36 demethylation (GO:0070544)2.31009566
114regulation of p38MAPK cascade (GO:1900744)2.29894480
115positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.29620057
116collagen metabolic process (GO:0032963)2.29555238
117chondrocyte proliferation (GO:0035988)2.29474763
118cellular response to virus (GO:0098586)2.29432883
119epithelial cell differentiation involved in prostate gland development (GO:0060742)2.28840441
120protein targeting to plasma membrane (GO:0072661)2.27980901
121bundle of His cell to Purkinje myocyte communication (GO:0086069)2.27934259
122mesodermal cell differentiation (GO:0048333)2.27764883
123adherens junction organization (GO:0034332)2.27715529
124regulation of mammary gland epithelial cell proliferation (GO:0033599)2.27567628
125actin filament bundle organization (GO:0061572)2.27183903
126actin filament bundle assembly (GO:0051017)2.27183903
127gastrulation with mouth forming second (GO:0001702)2.26551213
128positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.26071063
129lysine catabolic process (GO:0006554)2.26013179
130lysine metabolic process (GO:0006553)2.26013179
1314-hydroxyproline metabolic process (GO:0019471)2.25651052
132embryonic camera-type eye morphogenesis (GO:0048596)2.25490712
133semaphorin-plexin signaling pathway (GO:0071526)2.25439253
134positive regulation of blood vessel endothelial cell migration (GO:0043536)2.24879986
135positive regulation of endothelial cell apoptotic process (GO:2000353)2.24873251
136negative regulation of chondrocyte differentiation (GO:0032331)2.24778516
1372-oxoglutarate metabolic process (GO:0006103)2.24743891
138G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071992.24562840
139triglyceride-rich lipoprotein particle remodeling (GO:0034370)2.24542739
140regulation of apoptotic process involved in morphogenesis (GO:1902337)2.23791627
141maternal placenta development (GO:0001893)2.23671431
142multicellular organismal macromolecule metabolic process (GO:0044259)2.23626823
143regulation of establishment of planar polarity (GO:0090175)2.23597436
144response to laminar fluid shear stress (GO:0034616)2.23253981
145trabecula formation (GO:0060343)2.22890023
146collagen catabolic process (GO:0030574)2.22833075
147positive regulation of triglyceride metabolic process (GO:0090208)2.22773260
148positive regulation of fatty acid metabolic process (GO:0045923)2.22447812
149craniofacial suture morphogenesis (GO:0097094)2.22401870
150regulation of cholesterol storage (GO:0010885)2.21902149
151white fat cell differentiation (GO:0050872)2.21781840
152regulation of defense response to virus by virus (GO:0050690)2.21700745
153Rho protein signal transduction (GO:0007266)2.21634422
154protein localization to endosome (GO:0036010)2.21612599
155Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.21510097
156heart morphogenesis (GO:0003007)2.21415588
157sarcomere organization (GO:0045214)2.21287310
158positive regulation of epidermal cell differentiation (GO:0045606)2.21152978
159outer ear morphogenesis (GO:0042473)2.20409725
160regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.18481185
161regulation of fibrinolysis (GO:0051917)2.18386979
162regulation of triglyceride biosynthetic process (GO:0010866)2.17832281
163midgut development (GO:0007494)2.16640085
164fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)2.15533116

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human4.12516299
2PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.26719976
3ESR1_17901129_ChIP-ChIP_LIVER_Mouse3.20755020
4NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.99262112
5RARG_19884340_ChIP-ChIP_MEFs_Mouse2.74193040
6RXR_22158963_ChIP-Seq_LIVER_Mouse2.51077413
7PPARA_22158963_ChIP-Seq_LIVER_Mouse2.37326003
8CLOCK_20551151_ChIP-Seq_293T_Human2.35753490
9TRIM28_21343339_ChIP-Seq_HEK293_Human2.33250842
10* KDM2B_26808549_Chip-Seq_SUP-B15_Human2.32669947
11LXR_22158963_ChIP-Seq_LIVER_Mouse2.18955152
12* KDM2B_26808549_Chip-Seq_DND41_Human2.10879917
13NR1I2_20693526_ChIP-Seq_LIVER_Mouse2.10411776
14STAT6_21828071_ChIP-Seq_BEAS2B_Human2.01916363
15* ELK3_25401928_ChIP-Seq_HUVEC_Human2.00952466
16* LXR_22292898_ChIP-Seq_THP-1_Human2.00128753
17WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.97436643
18ZNF263_19887448_ChIP-Seq_K562_Human1.91677444
19EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.89697089
20THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.87203081
21RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.86172925
22* ESR2_21235772_ChIP-Seq_MCF-7_Human1.85199969
23MYC_22102868_ChIP-Seq_BL_Human1.83611274
24* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.82053767
25* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.81595880
26* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.81525830
27KDM2B_26808549_Chip-Seq_K562_Human1.80390319
28* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.80037811
29* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.79461443
30* TCF7_22412390_ChIP-Seq_EML_Mouse1.78221421
31NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.76697053
32* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.71961896
33RACK7_27058665_Chip-Seq_MCF-7_Human1.70723357
34KDM2B_26808549_Chip-Seq_JURKAT_Human1.69928034
35STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.63935928
36P300_27058665_Chip-Seq_ZR-75-30cells_Human1.62150030
37TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.58824929
38* ZFP281_27345836_Chip-Seq_ESCs_Mouse1.56299702
39TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.55830624
40ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.55355213
41DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.54434280
42* TBX20_22328084_ChIP-Seq_HEART_Mouse1.51076501
43* TBX20_22080862_ChIP-Seq_HEART_Mouse1.51076501
44STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.50899503
45* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.48986490
46PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.48224719
47SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.46761996
48FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.45709687
49* SOX9_24532713_ChIP-Seq_HFSC_Mouse1.43912751
50ESR1_20079471_ChIP-ChIP_T-47D_Human1.39123142
51EGR1_19374776_ChIP-ChIP_THP-1_Human1.34863626
52NFIB_24661679_ChIP-Seq_LUNG_Mouse1.34650853
53* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.34169599
54* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.33425617
55* RUNX1_27514584_Chip-Seq_MCF-7_Human1.30137866
56VDR_21846776_ChIP-Seq_THP-1_Human1.30088385
57DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.29871970
58KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.29431093
59* SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.29358353
60* SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.29358353
61* VDR_24763502_ChIP-Seq_THP-1_Human1.29302649
62CTCF_27219007_Chip-Seq_ERYTHROID_Human1.27851632
63* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.27115421
64FOXO3_23340844_ChIP-Seq_DLD1_Human1.26760970
65DROSHA_22980978_ChIP-Seq_HELA_Human1.26008615
66CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.25644420
67SMC4_20622854_ChIP-Seq_HELA_Human1.24808489
68* TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.24545365
69* RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.24374942
70SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.24285439
71ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.23778077
72* CREB1_26743006_Chip-Seq_LNCaP_Human1.23547099
73ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.23146637
74FOXA2_19822575_ChIP-Seq_HepG2_Human1.22682890
75DNAJC2_21179169_ChIP-ChIP_NT2_Human1.22335893
76HIF1A_21447827_ChIP-Seq_MCF-7_Human1.22285030
77KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.21545745
78* CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.21312256
79ESR1_21235772_ChIP-Seq_MCF-7_Human1.20813510
80EP300_21415370_ChIP-Seq_HL-1_Mouse1.20501208
81RUNX1_22412390_ChIP-Seq_EML_Mouse1.20422104
82TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.20412489
83* ISL1_27105846_Chip-Seq_CPCs_Mouse1.20347500
84* PPAR_26484153_Chip-Seq_NCI-H1993_Human1.18038408
85SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.16714486
86* ATF3_27146783_Chip-Seq_COLON_Human1.16327628
87TET1_21451524_ChIP-Seq_MESCs_Mouse1.16200404
88P68_20966046_ChIP-Seq_HELA_Human1.15668219
89BRD4_27068464_Chip-Seq_AML-cells_Mouse1.15198324
90* SOX2_27498859_Chip-Seq_STOMACH_Mouse1.14391239
91VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.11148382
92TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.10112066
93* MAF_26560356_Chip-Seq_TH2_Human1.08542043
94* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.08034514
95* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.06378355
96TP53_22127205_ChIP-Seq_IMR90_Human1.05372168
97* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.05311087
98FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.04957233
99* SMC1_22415368_ChIP-Seq_MEFs_Mouse1.03873741
100TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.03850616
101TP53_20018659_ChIP-ChIP_R1E_Mouse1.03351064
102NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.02241640
103RNF2_18974828_ChIP-Seq_MESCs_Mouse1.01341699
104EZH2_18974828_ChIP-Seq_MESCs_Mouse1.01341699
105KLF4_18555785_ChIP-Seq_MESCs_Mouse1.00546450
106UBF1/2_26484160_Chip-Seq_HMECs_Human0.99486336
107MAF_26560356_Chip-Seq_TH1_Human0.98304061
108SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.97785824
109* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.97423193
110HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.97159700
111CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.95736418
112AHR_22903824_ChIP-Seq_MCF-7_Human0.95102452
113CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.94868784
114FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.94695058
115* UTX_26944678_Chip-Seq_JUKART_Human0.92826189
116* TP63_22573176_ChIP-Seq_HFKS_Human0.92565115
117SA1_27219007_Chip-Seq_ERYTHROID_Human0.92398772
118MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.92296142
119TP53_23651856_ChIP-Seq_MEFs_Mouse0.90965050
120* NCOR1_26117541_ChIP-Seq_K562_Human0.90674144
121E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.90548517
122GATA1_19941826_ChIP-Seq_K562_Human0.90254969
123CJUN_26792858_Chip-Seq_BT549_Human0.90155406
124* TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.88786773
125ERG_21242973_ChIP-ChIP_JURKAT_Human0.88254501
126GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.88176654
127SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.86978058
128* P63_26484246_Chip-Seq_KERATINOCYTES_Human0.85751688

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003705_abnormal_hypodermis_morpholog5.15050203
2MP0008438_abnormal_cutaneous_collagen4.58824233
3MP0005275_abnormal_skin_tensile3.59414754
4MP0003279_aneurysm2.62162191
5MP0005503_abnormal_tendon_morphology2.29597180
6MP0005670_abnormal_white_adipose2.20884844
7MP0003566_abnormal_cell_adhesion2.20476568
8MP0005623_abnormal_meninges_morphology2.17456395
9MP0004272_abnormal_basement_membrane2.14884467
10MP0005360_urolithiasis2.11319862
11MP0005451_abnormal_body_composition1.99867829
12MP0000751_myopathy1.97057267
13MP0005076_abnormal_cell_differentiation1.96537259
14MP0005409_darkened_coat_color1.92889246
15MP0004264_abnormal_extraembryonic_tissu1.92801189
16MP0004185_abnormal_adipocyte_glucose1.82820371
17MP0001958_emphysema1.81756885
18MP0002837_dystrophic_cardiac_calcinosis1.81646996
19MP0010234_abnormal_vibrissa_follicle1.81444519
20MP0002060_abnormal_skin_morphology1.78005950
21MP0005666_abnormal_adipose_tissue1.73905177
22MP0009384_cardiac_valve_regurgitation1.72112962
23MP0003252_abnormal_bile_duct1.70075310
24MP0002139_abnormal_hepatobiliary_system1.69858472
25MP0010352_gastrointestinal_tract_polyps1.69807248
26MP0003300_gastrointestinal_ulcer1.69666079
27MP0000733_abnormal_muscle_development1.66562675
28MP0004130_abnormal_muscle_cell1.65485570
29MP0003045_fibrosis1.60419662
30MP0005375_adipose_tissue_phenotype1.59701022
31MP0005023_abnormal_wound_healing1.57337316
32MP0009053_abnormal_anal_canal1.56788251
33MP0003091_abnormal_cell_migration1.54783429
34MP0004947_skin_inflammation1.52941121
35MP0008260_abnormal_autophagy1.48798837
36MP0005365_abnormal_bile_salt1.46978985
37MP0001849_ear_inflammation1.46547789
38MP0010368_abnormal_lymphatic_system1.46127876
39MP0000858_altered_metastatic_potential1.45968406
40MP0004087_abnormal_muscle_fiber1.44398821
41MP0010030_abnormal_orbit_morphology1.42521546
42MP0000003_abnormal_adipose_tissue1.41335084
43MP0008961_abnormal_basal_metabolism1.41001691
44MP0003763_abnormal_thymus_physiology1.40841387
45MP0004381_abnormal_hair_follicle1.35076272
46MP0002796_impaired_skin_barrier1.35070574
47MP0005058_abnormal_lysosome_morphology1.33924931
48MP0003385_abnormal_body_wall1.33560963
49MP0009780_abnormal_chondrocyte_physiolo1.33217116
50MP0000537_abnormal_urethra_morphology1.32830580
51MP0010329_abnormal_lipoprotein_level1.32776309
52MP0003436_decreased_susceptibility_to1.32260718
53MP0010630_abnormal_cardiac_muscle1.30298630
54MP0001216_abnormal_epidermal_layer1.29674451
55MP0002896_abnormal_bone_mineralization1.28817009
56MP0002098_abnormal_vibrissa_morphology1.26824533
57MP0000750_abnormal_muscle_regeneration1.23683103
58MP0000579_abnormal_nail_morphology1.23271108
59MP0004084_abnormal_cardiac_muscle1.22984587
60MP0005508_abnormal_skeleton_morphology1.22684104
61MP0005085_abnormal_gallbladder_physiolo1.22030972
62MP0003115_abnormal_respiratory_system1.21492469
63MP0009840_abnormal_foam_cell1.19717015
64MP0002254_reproductive_system_inflammat1.19502306
65MP0006054_spinal_hemorrhage1.19044901
66MP0002168_other_aberrant_phenotype1.17281917
67MP0005330_cardiomyopathy1.16131058
68MP0002108_abnormal_muscle_morphology1.16071043
69MP0000767_abnormal_smooth_muscle1.15829665
70MP0001243_abnormal_dermal_layer1.14873716
71MP0002234_abnormal_pharynx_morphology1.12665854
72MP0000467_abnormal_esophagus_morphology1.10379062
73MP0002249_abnormal_larynx_morphology1.10293848
74MP0003191_abnormal_cellular_cholesterol1.10159001
75MP0000678_abnormal_parathyroid_gland1.09355470
76MP0000013_abnormal_adipose_tissue1.06704976
77MP0006138_congestive_heart_failure1.06443526
78MP0002998_abnormal_bone_remodeling1.05857550
79MP0001873_stomach_inflammation1.05723236
80MP0004510_myositis1.05561880
81MP0000534_abnormal_ureter_morphology1.05213151
82MP0000428_abnormal_craniofacial_morphol1.04360806
83MP0003941_abnormal_skin_development1.03614788
84MP0005248_abnormal_Harderian_gland1.02570105
85MP0009278_abnormal_bone_marrow1.00155579
86MP0005257_abnormal_intraocular_pressure0.98754991
87MP0000759_abnormal_skeletal_muscle0.97814519
88MP0009931_abnormal_skin_appearance0.96723224
89MP0005621_abnormal_cell_physiology0.95845124
90MP0000377_abnormal_hair_follicle0.95439146
91MP0002128_abnormal_blood_circulation0.94895834
92MP0001851_eye_inflammation0.93496202
93MP0003942_abnormal_urinary_system0.93275530
94MP0002089_abnormal_postnatal_growth/wei0.92007815
95MP0001348_abnormal_lacrimal_gland0.91472644
96MP0002933_joint_inflammation0.90979889
97MP0003172_abnormal_lysosome_physiology0.90162950
98MP0010771_integument_phenotype0.89187249
99MP0003453_abnormal_keratinocyte_physiol0.87189204
100MP0002925_abnormal_cardiovascular_devel0.86984649
101MP0005385_cardiovascular_system_phenoty0.86805893
102MP0001544_abnormal_cardiovascular_syste0.86805893
103MP0005390_skeleton_phenotype0.86594385
104MP0002932_abnormal_joint_morphology0.86271557
105MP0000627_abnormal_mammary_gland0.85485972
106MP0004858_abnormal_nervous_system0.83734934
107MP0002295_abnormal_pulmonary_circulatio0.83638962
108MP0000462_abnormal_digestive_system0.83573551
109MP0005083_abnormal_biliary_tract0.83543824
110MP0004233_abnormal_muscle_weight0.83187874
111MP0001533_abnormal_skeleton_physiology0.82690341
112MP0000609_abnormal_liver_physiology0.80544534
113MP0003828_pulmonary_edema0.80061768
114MP0000266_abnormal_heart_morphology0.79405201
115MP0005501_abnormal_skin_physiology0.78929845
116MP0003935_abnormal_craniofacial_develop0.78877059
117MP0002282_abnormal_trachea_morphology0.77730861
118MP0009672_abnormal_birth_weight0.75609597
119MP0009333_abnormal_splenocyte_physiolog0.74721268
120MP0002269_muscular_atrophy0.74716774
121MP0005187_abnormal_penis_morphology0.74265810
122MP0001614_abnormal_blood_vessel0.73776258
123MP0004782_abnormal_surfactant_physiolog0.73721587
124MP0004808_abnormal_hematopoietic_stem0.73510442
125MP0002396_abnormal_hematopoietic_system0.73361653
126MP0009115_abnormal_fat_cell0.73219778
127MP0002086_abnormal_extraembryonic_tissu0.73196496
128MP0003283_abnormal_digestive_organ0.72864840
129MP0001340_abnormal_eyelid_morphology0.72803364
130MP0002877_abnormal_melanocyte_morpholog0.72441776
131MP0000566_synostosis0.72191632
132MP0003448_altered_tumor_morphology0.71683757
133MP0001542_abnormal_bone_strength0.71648475
134MP0002118_abnormal_lipid_homeostasis0.71561881
135MP0000163_abnormal_cartilage_morphology0.70847193
136MP0009250_abnormal_appendicular_skeleto0.70602124
137MP0002971_abnormal_brown_adipose0.70003336
138MP0000762_abnormal_tongue_morphology0.69323395
139MP0001299_abnormal_eye_distance/0.69103986
140MP0004197_abnormal_fetal_growth/weight/0.68716018

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)5.44500129
2Shallow orbits (HP:0000586)4.72366063
3Premature rupture of membranes (HP:0001788)4.60830658
4Broad metatarsal (HP:0001783)4.07722060
5Ankle contracture (HP:0006466)3.94269051
6Cerebral aneurysm (HP:0004944)3.80326965
7Atrophic scars (HP:0001075)3.70762984
8Broad face (HP:0000283)3.64875183
9Increased connective tissue (HP:0009025)3.41385349
10Obstructive sleep apnea (HP:0002870)3.34220148
11Type 1 muscle fiber predominance (HP:0003803)3.29156810
12Aortic dissection (HP:0002647)3.17006044
13Mitral valve prolapse (HP:0001634)3.16756642
14Peritonitis (HP:0002586)3.09752519
15Fragile skin (HP:0001030)3.07843171
16Right ventricular cardiomyopathy (HP:0011663)3.05958271
17Bladder diverticulum (HP:0000015)3.04986500
18Arterial tortuosity (HP:0005116)3.03306905
19Deep venous thrombosis (HP:0002625)2.84617038
20Aortic aneurysm (HP:0004942)2.81657810
21Dilatation of the ascending aorta (HP:0005111)2.76118282
22Distal lower limb muscle weakness (HP:0009053)2.75724565
23Increased variability in muscle fiber diameter (HP:0003557)2.70386325
24Short 4th metacarpal (HP:0010044)2.69409493
25Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.69409493
26Genu recurvatum (HP:0002816)2.63518183
27Aneurysm (HP:0002617)2.58612250
28Mildly elevated creatine phosphokinase (HP:0008180)2.56572335
29Hyporeflexia of lower limbs (HP:0002600)2.54909843
30Abnormality of the 4th metacarpal (HP:0010012)2.51558896
31Follicular hyperkeratosis (HP:0007502)2.50750703
32Lymphangioma (HP:0100764)2.49133123
33Turricephaly (HP:0000262)2.44131645
34Vertebral compression fractures (HP:0002953)2.43657236
35Spinal rigidity (HP:0003306)2.41064950
36Hyperacusis (HP:0010780)2.40513735
37Blue sclerae (HP:0000592)2.40413538
38Abnormality of skeletal muscle fiber size (HP:0012084)2.35708407
39Deviation of the hallux (HP:0010051)2.32446708
40Flat acetabular roof (HP:0003180)2.29181518
41Long palpebral fissure (HP:0000637)2.28521682
42Osteolytic defects of the hand bones (HP:0009699)2.28207479
43Osteolytic defects of the phalanges of the hand (HP:0009771)2.28207479
44Bowel diverticulosis (HP:0005222)2.26314095
45Short nail (HP:0001799)2.25733564
46Slender build (HP:0001533)2.25559086
47Ectopia lentis (HP:0001083)2.25117453
48Hallux valgus (HP:0001822)2.24876045
49Distal upper limb amyotrophy (HP:0007149)2.20237914
50Upper limb amyotrophy (HP:0009129)2.20237914
51Spondylolisthesis (HP:0003302)2.18790907
52Milia (HP:0001056)2.16010805
53Wide anterior fontanel (HP:0000260)2.15134490
54Disproportionate tall stature (HP:0001519)2.14814669
55Soft skin (HP:0000977)2.13402371
56Sudden death (HP:0001699)2.12168474
57Neonatal short-limb short stature (HP:0008921)2.11936670
58Cervical subluxation (HP:0003308)2.10062746
59Muscle fiber splitting (HP:0003555)2.08873746
60Ulnar bowing (HP:0003031)2.08114964
61Dislocated radial head (HP:0003083)2.07148742
62Difficulty running (HP:0009046)2.06668288
63Abnormality of the Achilles tendon (HP:0005109)2.04340077
64Hyperextensible skin (HP:0000974)2.04066275
65Natal tooth (HP:0000695)2.03972472
66Overgrowth (HP:0001548)2.03624133
67Thin bony cortex (HP:0002753)2.03176912
68Renovascular hypertension (HP:0100817)2.02520658
69Abnormality of the radial head (HP:0003995)2.01596330
70Ventricular tachycardia (HP:0004756)2.01477322
71Abnormality of the distal phalanx of the thumb (HP:0009617)2.01378389
72Xanthomatosis (HP:0000991)2.00788768
73Selective tooth agenesis (HP:0001592)2.00666107
74Enlarged penis (HP:0000040)2.00361805
75Wrist flexion contracture (HP:0001239)1.99076045
76Bronchomalacia (HP:0002780)1.98366317
77Achilles tendon contracture (HP:0001771)1.98149037
78Sparse lateral eyebrow (HP:0005338)1.96710744
79Difficulty climbing stairs (HP:0003551)1.96534919
80Myocardial infarction (HP:0001658)1.95604296
81Lower limb amyotrophy (HP:0007210)1.94762793
82Camptodactyly of toe (HP:0001836)1.94316115
83Absent frontal sinuses (HP:0002688)1.93973042
84Abnormality of the distal phalanges of the toes (HP:0010182)1.93554211
85Macroorchidism (HP:0000053)1.93345366
86Striae distensae (HP:0001065)1.92886467
87J-shaped sella turcica (HP:0002680)1.91946225
88Coronal craniosynostosis (HP:0004440)1.91714229
89Abnormality of oral frenula (HP:0000190)1.91105509
90Long toe (HP:0010511)1.90269111
91Buphthalmos (HP:0000557)1.87130195
92Alopecia of scalp (HP:0002293)1.86244525
93Infantile muscular hypotonia (HP:0008947)1.84169888
94Aortic regurgitation (HP:0001659)1.83443013
95Stridor (HP:0010307)1.80815479
96Scapular winging (HP:0003691)1.78240938
97Round ear (HP:0100830)1.78147342
98Easy fatigability (HP:0003388)1.77790921
99Wormian bones (HP:0002645)1.76267273
100Distal lower limb amyotrophy (HP:0008944)1.75036167
101Ankyloglossia (HP:0010296)1.74251587
102Elfin facies (HP:0004428)1.73720811
103Joint laxity (HP:0001388)1.73572369
104Renal duplication (HP:0000075)1.72845305
105Premature skin wrinkling (HP:0100678)1.72673761
106Generalized amyotrophy (HP:0003700)1.72249826
107Centrally nucleated skeletal muscle fibers (HP:0003687)1.72172788
108Abnormality of the fingertips (HP:0001211)1.72076658
109Elbow flexion contracture (HP:0002987)1.71593292
110Biconcave vertebral bodies (HP:0004586)1.71441505
111Micronodular cirrhosis (HP:0001413)1.71069502
112Mitral regurgitation (HP:0001653)1.69413078
113Abnormal ossification of hand bones (HP:0005921)1.69182485
114Long eyelashes (HP:0000527)1.68808852
115Trismus (HP:0000211)1.68576683
116Abnormality of the peritoneum (HP:0002585)1.68392281
117Bowing of the arm (HP:0006488)1.67152273
118Bowed forearm bones (HP:0003956)1.67152273
119Abnormality of dentin (HP:0010299)1.66822610
120Tibial bowing (HP:0002982)1.66300855
121Venous abnormality (HP:0002624)1.65701992
122Rectal prolapse (HP:0002035)1.64638860
123Arnold-Chiari malformation (HP:0002308)1.64542162
124Hand muscle atrophy (HP:0009130)1.63926151
125Increased density of long bones (HP:0006392)1.63839759
126Vascular tortuosity (HP:0004948)1.63649643
127Ulnar deviation of the wrist (HP:0003049)1.63500933
128Mitral stenosis (HP:0001718)1.62023218
129Nail dystrophy (HP:0008404)1.61846420
130Persistence of primary teeth (HP:0006335)1.60913774
131Narrow palate (HP:0000189)1.59713633
132Advanced eruption of teeth (HP:0006288)1.59451891
133Asymmetry of the thorax (HP:0001555)1.58646297
134Venous insufficiency (HP:0005293)1.57958880
135Subacute progressive viral hepatitis (HP:0006572)1.57485414
136Joint stiffness (HP:0001387)1.57250535
137Spinal cord compression (HP:0002176)1.56341986
138Vertebral arch anomaly (HP:0008438)1.56029711
139Coxa vara (HP:0002812)1.56000062
140Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.55921723
141Hemorrhage of the eye (HP:0011885)1.55366699
142Thin ribs (HP:0000883)1.55062828
143Hypoalphalipoproteinemia (HP:0003233)1.53456632
144Acanthosis nigricans (HP:0000956)1.53379014
145Spinal cord lesions (HP:0100561)1.53328803
146Syringomyelia (HP:0003396)1.53328803

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.95174960
2PKN23.71392958
3SIK13.60896323
4ERN12.94890684
5TTN2.94840898
6EEF2K2.87760611
7SMG12.82922533
8PRPF4B2.79394493
9MAP3K102.73194215
10RIPK12.54160841
11MST1R2.37759754
12PDGFRA2.32134692
13LATS12.08356148
14PTK62.07940125
15DDR21.97299541
16IRAK31.87037886
17CDK121.86642692
18FGFR41.77640085
19CAMK1G1.75206979
20CAMK1D1.75123067
21EPHB21.72324609
22LATS21.68243629
23ICK1.67779833
24DMPK1.61236357
25EPHB11.57968398
26BMX1.52722171
27MAP3K71.38162090
28SIK21.36432759
29MET1.33559280
30MTOR1.32714386
31TESK11.29937560
32FGFR21.27911295
33PTK21.25205713
34SIK31.23936137
35TAOK11.23306449
36TGFBR21.21769190
37LRRK21.20787929
38LMTK21.12384085
39FER1.04357718
40PAK21.04155056
41MARK21.04008228
42MAP3K131.03467516
43ZAP701.01881345
44EPHA30.99170963
45PDGFRB0.98243616
46FGFR10.96300044
47PRKCH0.95591683
48TYRO30.94055099
49PAK30.93039832
50NTRK10.90417914
51PRKD20.90055805
52MAP4K10.89999082
53FGFR30.89173310
54PAK40.87801913
55RET0.87536739
56PRKD30.87196719
57JAK10.85285295
58PRKD10.85009497
59MELK0.81406998
60TAOK20.75739328
61ILK0.74916903
62MAP2K20.73414930
63CDK60.73221911
64PHKG20.70117852
65PHKG10.70117852
66STK100.70079836
67MAP3K10.68123074
68MAP3K90.67556268
69PDPK10.65159609
70CDC42BPA0.64508834
71ROCK10.63531195
72KSR20.62835569
73BCKDK0.60351229
74ERBB20.59564120
75MAPK120.59080600
76MAP3K60.58929762
77STK380.58679363
78PTK2B0.58289182
79ALK0.58104891
80DYRK1B0.57665098
81CAMKK10.55576601
82TBK10.54786634
83CAMK40.54001569
84RPS6KA20.53852377
85TRPM70.53532985
86MAPK70.53165045
87BRD40.52791381
88STK30.51698918
89MAP2K30.49867934
90PRKG20.49039221
91MYLK0.47718169
92JAK30.45816523
93STK110.45705814
94IRAK20.45178851
95MAPKAPK20.45116343
96EPHA20.45001186
97PIK3CA0.44939669
98GRK60.44929602
99TESK20.44847544
100CHUK0.44265145
101NME20.43338596
102SGK30.42382094
103CSK0.42225954
104CDK90.42147023
105ARAF0.41519448
106CDK70.41508467
107ITK0.41470407
108PRKAA20.41298466
109NEK60.41237177
110IRAK40.40706642
111HCK0.39400216
112MAP3K80.39138326
113SRC0.38847927
114ROCK20.38424427
115CSF1R0.37946395
116MAP3K140.37867450
117PAK60.37653909
118FLT30.36227725
119RPS6KA10.35626593
120MAPK110.34536320
121MAP3K30.33984187
122INSR0.33133708
123RPS6KL10.32690162
124RPS6KC10.32690162
125PRKAA10.32291846
126TYK20.31678275
127WNK10.31591581
128CDK40.31513753
129RPS6KA60.31239351
130MAPKAPK30.30643381
131RPS6KB20.29843286
132JAK20.29509555
133RPS6KA40.29058769
134DAPK30.28913570
135GSK3A0.28798743
136HIPK20.28647593

Predicted pathways (KEGG)

RankGene SetZ-score
1Nitrogen metabolism_Homo sapiens_hsa009102.65646104
2Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.40046430
3ECM-receptor interaction_Homo sapiens_hsa045121.93853406
4Thyroid cancer_Homo sapiens_hsa052161.77377125
5Lysine degradation_Homo sapiens_hsa003101.77023013
6Focal adhesion_Homo sapiens_hsa045101.70622553
7PPAR signaling pathway_Homo sapiens_hsa033201.67192369
8Primary bile acid biosynthesis_Homo sapiens_hsa001201.66924687
9Arginine biosynthesis_Homo sapiens_hsa002201.65192149
10Fatty acid degradation_Homo sapiens_hsa000711.65075179
11Other glycan degradation_Homo sapiens_hsa005111.55654782
122-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.51399102
13Basal cell carcinoma_Homo sapiens_hsa052171.50460401
14Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.48727103
15Adherens junction_Homo sapiens_hsa045201.48210034
16Proteoglycans in cancer_Homo sapiens_hsa052051.42593697
17Dilated cardiomyopathy_Homo sapiens_hsa054141.42289982
18Fatty acid metabolism_Homo sapiens_hsa012121.40337401
19Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.39910423
20Insulin resistance_Homo sapiens_hsa049311.37761118
21Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.33963354
22ErbB signaling pathway_Homo sapiens_hsa040121.30840310
23Amoebiasis_Homo sapiens_hsa051461.28117026
24Bile secretion_Homo sapiens_hsa049761.26206759
25Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.25671858
26Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.24634597
27Glycosaminoglycan degradation_Homo sapiens_hsa005311.24465147
28Tryptophan metabolism_Homo sapiens_hsa003801.24131019
29Chronic myeloid leukemia_Homo sapiens_hsa052201.22528783
30Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.18139295
31AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.18076810
32Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.17319335
33Notch signaling pathway_Homo sapiens_hsa043301.15899858
34Hepatitis C_Homo sapiens_hsa051601.14839941
35Protein digestion and absorption_Homo sapiens_hsa049741.13954508
36T cell receptor signaling pathway_Homo sapiens_hsa046601.13465309
37Complement and coagulation cascades_Homo sapiens_hsa046101.13444658
38Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.09991960
39Adipocytokine signaling pathway_Homo sapiens_hsa049201.09878601
40Choline metabolism in cancer_Homo sapiens_hsa052311.08414700
41Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.08062953
42Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.06387677
43Phosphatidylinositol signaling system_Homo sapiens_hsa040701.05687445
44TNF signaling pathway_Homo sapiens_hsa046681.04313061
45Viral myocarditis_Homo sapiens_hsa054161.03782938
46Caffeine metabolism_Homo sapiens_hsa002321.03619269
47Small cell lung cancer_Homo sapiens_hsa052221.03484269
48Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.03439856
49Hepatitis B_Homo sapiens_hsa051611.02849085
50Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.02674439
51mTOR signaling pathway_Homo sapiens_hsa041501.02646580
52Endometrial cancer_Homo sapiens_hsa052131.02320372
53AMPK signaling pathway_Homo sapiens_hsa041521.01684379
54Prolactin signaling pathway_Homo sapiens_hsa049171.01227345
55Bladder cancer_Homo sapiens_hsa052191.00361264
56Prion diseases_Homo sapiens_hsa050201.00266366
57Hippo signaling pathway_Homo sapiens_hsa043900.98827414
58Inositol phosphate metabolism_Homo sapiens_hsa005620.98013557
59Propanoate metabolism_Homo sapiens_hsa006400.97601896
60Osteoclast differentiation_Homo sapiens_hsa043800.97145096
61Endocytosis_Homo sapiens_hsa041440.96497630
62Longevity regulating pathway - mammal_Homo sapiens_hsa042110.96383287
63GnRH signaling pathway_Homo sapiens_hsa049120.96091874
64Fatty acid biosynthesis_Homo sapiens_hsa000610.95451220
65Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.95087673
66Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.94014125
67Glioma_Homo sapiens_hsa052140.92148165
68Acute myeloid leukemia_Homo sapiens_hsa052210.91732977
69Hedgehog signaling pathway_Homo sapiens_hsa043400.90602215
70Central carbon metabolism in cancer_Homo sapiens_hsa052300.90413850
71Insulin signaling pathway_Homo sapiens_hsa049100.89973826
72Butanoate metabolism_Homo sapiens_hsa006500.89684304
73Thyroid hormone signaling pathway_Homo sapiens_hsa049190.89584457
74Apoptosis_Homo sapiens_hsa042100.86841426
75Pentose phosphate pathway_Homo sapiens_hsa000300.84945824
76Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.84382417
77Non-small cell lung cancer_Homo sapiens_hsa052230.83901790
78HTLV-I infection_Homo sapiens_hsa051660.82420065
79Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.82342752
80Leukocyte transendothelial migration_Homo sapiens_hsa046700.81614710
81MicroRNAs in cancer_Homo sapiens_hsa052060.80974852
82Renal cell carcinoma_Homo sapiens_hsa052110.78121247
83Toll-like receptor signaling pathway_Homo sapiens_hsa046200.77283924
84Pancreatic cancer_Homo sapiens_hsa052120.77244017
85Sphingolipid signaling pathway_Homo sapiens_hsa040710.77048067
86VEGF signaling pathway_Homo sapiens_hsa043700.76938081
87Glucagon signaling pathway_Homo sapiens_hsa049220.76649979
88Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.76245161
89Regulation of actin cytoskeleton_Homo sapiens_hsa048100.73359494
90Platelet activation_Homo sapiens_hsa046110.72763438
91Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.72602539
92Shigellosis_Homo sapiens_hsa051310.72526315
93Estrogen signaling pathway_Homo sapiens_hsa049150.72016198
94Fructose and mannose metabolism_Homo sapiens_hsa000510.71709505
95Measles_Homo sapiens_hsa051620.71302888
96Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.71160512
97Rap1 signaling pathway_Homo sapiens_hsa040150.70711314
98Melanogenesis_Homo sapiens_hsa049160.70666947
99Axon guidance_Homo sapiens_hsa043600.70103142
100Fat digestion and absorption_Homo sapiens_hsa049750.69811040
101Type II diabetes mellitus_Homo sapiens_hsa049300.69362216
102MAPK signaling pathway_Homo sapiens_hsa040100.68150610
103Influenza A_Homo sapiens_hsa051640.67179690
104Neurotrophin signaling pathway_Homo sapiens_hsa047220.66956968
105Aldosterone synthesis and secretion_Homo sapiens_hsa049250.66755427
106Staphylococcus aureus infection_Homo sapiens_hsa051500.65511222
107Tight junction_Homo sapiens_hsa045300.65046625
108Galactose metabolism_Homo sapiens_hsa000520.64890338
109Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.64711597
110HIF-1 signaling pathway_Homo sapiens_hsa040660.64579038
111Colorectal cancer_Homo sapiens_hsa052100.64500491
112Prostate cancer_Homo sapiens_hsa052150.64225137
113Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.64060847
114Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.63731792
115Pathways in cancer_Homo sapiens_hsa052000.63355431
116NF-kappa B signaling pathway_Homo sapiens_hsa040640.63222328
117PI3K-Akt signaling pathway_Homo sapiens_hsa041510.62547901
118Toxoplasmosis_Homo sapiens_hsa051450.61004907
119Viral carcinogenesis_Homo sapiens_hsa052030.59404349
120beta-Alanine metabolism_Homo sapiens_hsa004100.57810800
121Malaria_Homo sapiens_hsa051440.57077154
122Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.56162376
123Chemokine signaling pathway_Homo sapiens_hsa040620.55888088
124Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.55621458
125Wnt signaling pathway_Homo sapiens_hsa043100.55573465
126cGMP-PKG signaling pathway_Homo sapiens_hsa040220.55537756
127Long-term potentiation_Homo sapiens_hsa047200.54986226
128Starch and sucrose metabolism_Homo sapiens_hsa005000.54451240
129ABC transporters_Homo sapiens_hsa020100.53245780
130Phenylalanine metabolism_Homo sapiens_hsa003600.53129206
131Glycerolipid metabolism_Homo sapiens_hsa005610.52078508
132Dorso-ventral axis formation_Homo sapiens_hsa043200.51928077
133FoxO signaling pathway_Homo sapiens_hsa040680.51293758
134Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.51015936
135Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.50943708
136Carbon metabolism_Homo sapiens_hsa012000.50525077
137Cyanoamino acid metabolism_Homo sapiens_hsa004600.49742795
138Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.48865156
139B cell receptor signaling pathway_Homo sapiens_hsa046620.48679102
140Melanoma_Homo sapiens_hsa052180.48495502
141Phospholipase D signaling pathway_Homo sapiens_hsa040720.48143507

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