

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | adult feeding behavior (GO:0008343) | 8.51798522 |
| 2 | epithelial cilium movement (GO:0003351) | 6.91347125 |
| 3 | regulation of transmission of nerve impulse (GO:0051969) | 6.55007980 |
| 4 | positive regulation of catecholamine secretion (GO:0033605) | 6.39232153 |
| 5 | cilium movement (GO:0003341) | 5.88863068 |
| 6 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.68735390 |
| 7 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 5.40385191 |
| 8 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.08611611 |
| 9 | maturation of SSU-rRNA (GO:0030490) | 4.97583835 |
| 10 | ATP synthesis coupled proton transport (GO:0015986) | 4.92140094 |
| 11 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.92140094 |
| 12 | negative regulation of appetite (GO:0032099) | 4.74326238 |
| 13 | negative regulation of response to food (GO:0032096) | 4.74326238 |
| 14 | GTP biosynthetic process (GO:0006183) | 4.47504268 |
| 15 | axonemal dynein complex assembly (GO:0070286) | 4.40819177 |
| 16 | respiratory electron transport chain (GO:0022904) | 4.34384689 |
| 17 | chaperone-mediated protein transport (GO:0072321) | 4.30319337 |
| 18 | electron transport chain (GO:0022900) | 4.28601639 |
| 19 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.15638760 |
| 20 | NADH dehydrogenase complex assembly (GO:0010257) | 4.15638760 |
| 21 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.15638760 |
| 22 | UTP biosynthetic process (GO:0006228) | 4.12762784 |
| 23 | viral transcription (GO:0019083) | 4.11397531 |
| 24 | regulation of mitochondrial translation (GO:0070129) | 4.08223055 |
| 25 | positive regulation of neurological system process (GO:0031646) | 4.07800626 |
| 26 | protein complex biogenesis (GO:0070271) | 4.06414189 |
| 27 | translational termination (GO:0006415) | 4.04432275 |
| 28 | intracellular protein transmembrane import (GO:0044743) | 3.92101693 |
| 29 | left/right pattern formation (GO:0060972) | 3.88628650 |
| 30 | intraciliary transport (GO:0042073) | 3.87544221 |
| 31 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.85216857 |
| 32 | nucleoside diphosphate phosphorylation (GO:0006165) | 3.78447533 |
| 33 | protein polyglutamylation (GO:0018095) | 3.75453869 |
| 34 | UTP metabolic process (GO:0046051) | 3.70716871 |
| 35 | motile cilium assembly (GO:0044458) | 3.69081278 |
| 36 | cullin deneddylation (GO:0010388) | 3.67990957 |
| 37 | protein neddylation (GO:0045116) | 3.63708572 |
| 38 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.61696085 |
| 39 | ribosomal large subunit biogenesis (GO:0042273) | 3.58838298 |
| 40 | cotranslational protein targeting to membrane (GO:0006613) | 3.58150328 |
| 41 | translational elongation (GO:0006414) | 3.54437586 |
| 42 | ribosomal small subunit biogenesis (GO:0042274) | 3.54023039 |
| 43 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.53679747 |
| 44 | protein targeting to ER (GO:0045047) | 3.52385579 |
| 45 | protein deneddylation (GO:0000338) | 3.51726624 |
| 46 | CTP biosynthetic process (GO:0006241) | 3.50807859 |
| 47 | CTP metabolic process (GO:0046036) | 3.50807859 |
| 48 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 3.47415345 |
| 49 | inner mitochondrial membrane organization (GO:0007007) | 3.46047396 |
| 50 | ribosomal small subunit assembly (GO:0000028) | 3.40449998 |
| 51 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.39613642 |
| 52 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.35009014 |
| 53 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.31611376 |
| 54 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 3.31088810 |
| 55 | behavioral response to nicotine (GO:0035095) | 3.30958427 |
| 56 | cilium morphogenesis (GO:0060271) | 3.28545637 |
| 57 | protein localization to endoplasmic reticulum (GO:0070972) | 3.26542900 |
| 58 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.20120219 |
| 59 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.15625994 |
| 60 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.15625994 |
| 61 | regulation of feeding behavior (GO:0060259) | 3.15594782 |
| 62 | DNA double-strand break processing (GO:0000729) | 3.12397696 |
| 63 | cellular protein complex disassembly (GO:0043624) | 3.07182808 |
| 64 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 3.06609217 |
| 65 | spliceosomal snRNP assembly (GO:0000387) | 3.06080446 |
| 66 | ventricular system development (GO:0021591) | 3.05512276 |
| 67 | cilium or flagellum-dependent cell motility (GO:0001539) | 3.05163410 |
| 68 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 3.04436497 |
| 69 | pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208) | 3.04406241 |
| 70 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.03059450 |
| 71 | pseudouridine synthesis (GO:0001522) | 2.98704890 |
| 72 | nucleoside triphosphate biosynthetic process (GO:0009142) | 2.95729651 |
| 73 | ATP biosynthetic process (GO:0006754) | 2.95013620 |
| 74 | establishment of protein localization to mitochondrion (GO:0072655) | 2.94893736 |
| 75 | regulation of dopamine secretion (GO:0014059) | 2.93419955 |
| 76 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 2.92882611 |
| 77 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.92145742 |
| 78 | regulation of catecholamine secretion (GO:0050433) | 2.92040088 |
| 79 | intracellular protein transmembrane transport (GO:0065002) | 2.91146852 |
| 80 | proteasome assembly (GO:0043248) | 2.90002120 |
| 81 | sperm motility (GO:0030317) | 2.86505465 |
| 82 | regulation of response to food (GO:0032095) | 2.85673927 |
| 83 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.85214079 |
| 84 | viral life cycle (GO:0019058) | 2.82705558 |
| 85 | translation (GO:0006412) | 2.81718804 |
| 86 | positive regulation of amine transport (GO:0051954) | 2.81188058 |
| 87 | cellular component biogenesis (GO:0044085) | 2.80169644 |
| 88 | axoneme assembly (GO:0035082) | 2.79236605 |
| 89 | detection of temperature stimulus involved in sensory perception of pain (GO:0050965) | 2.79225389 |
| 90 | detection of temperature stimulus involved in sensory perception (GO:0050961) | 2.79225389 |
| 91 | protein localization to cilium (GO:0061512) | 2.76946471 |
| 92 | negative regulation of bone resorption (GO:0045779) | 2.76574534 |
| 93 | regulation of alternative mRNA splicing, via spliceosome (GO:0000381) | 2.76396924 |
| 94 | maturation of 5.8S rRNA (GO:0000460) | 2.76149720 |
| 95 | protein localization to mitochondrion (GO:0070585) | 2.75925025 |
| 96 | relaxation of smooth muscle (GO:0044557) | 2.75553405 |
| 97 | determination of left/right symmetry (GO:0007368) | 2.73897547 |
| 98 | GPI anchor biosynthetic process (GO:0006506) | 2.72443056 |
| 99 | negative regulation of mesenchymal cell apoptotic process (GO:2001054) | 2.71698965 |
| 100 | translational initiation (GO:0006413) | 2.71209280 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IGF1R_20145208_ChIP-Seq_DFB_Human | 3.91920443 |
| 2 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.63008281 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.41508235 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.31088140 |
| 5 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.30236957 |
| 6 | FUS_26573619_Chip-Seq_HEK293_Human | 2.89906288 |
| 7 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.80288396 |
| 8 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.65662999 |
| 9 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.63811159 |
| 10 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.63487123 |
| 11 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.38404291 |
| 12 | VDR_22108803_ChIP-Seq_LS180_Human | 2.35409511 |
| 13 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.31480569 |
| 14 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.24948504 |
| 15 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.23663262 |
| 16 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.22743624 |
| 17 | EWS_26573619_Chip-Seq_HEK293_Human | 2.22111626 |
| 18 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 2.16942579 |
| 19 | MYC_18940864_ChIP-ChIP_HL60_Human | 2.13085098 |
| 20 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.06690477 |
| 21 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.92173308 |
| 22 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.89031662 |
| 23 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.88919345 |
| 24 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.88526025 |
| 25 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.87291378 |
| 26 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.78343041 |
| 27 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.77771003 |
| 28 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.77226754 |
| 29 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.75520801 |
| 30 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.74837876 |
| 31 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.68735558 |
| 32 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.67606226 |
| 33 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.65204420 |
| 34 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.64445682 |
| 35 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.63993402 |
| 36 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.61936049 |
| 37 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.60490679 |
| 38 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.56784840 |
| 39 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.54586283 |
| 40 | P300_19829295_ChIP-Seq_ESCs_Human | 1.50589414 |
| 41 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.48737762 |
| 42 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.48469289 |
| 43 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.47628380 |
| 44 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.46975862 |
| 45 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.43004486 |
| 46 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.41261345 |
| 47 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.39031440 |
| 48 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.38887904 |
| 49 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.33093026 |
| 50 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.28907885 |
| 51 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.26280980 |
| 52 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.26280980 |
| 53 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.25698705 |
| 54 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.25145504 |
| 55 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.24423235 |
| 56 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.23499456 |
| 57 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.23046372 |
| 58 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.22284022 |
| 59 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.22162459 |
| 60 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.21656856 |
| 61 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.20978681 |
| 62 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.19650366 |
| 63 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.18095775 |
| 64 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.14664053 |
| 65 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.14189881 |
| 66 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.12447451 |
| 67 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.11147682 |
| 68 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.10323315 |
| 69 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.09777067 |
| 70 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.09777067 |
| 71 | NCOR_22424771_ChIP-Seq_293T_Human | 1.08631864 |
| 72 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.07562260 |
| 73 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.06856335 |
| 74 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.06385734 |
| 75 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.05746828 |
| 76 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.05352921 |
| 77 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.03458149 |
| 78 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.00718639 |
| 79 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.00581055 |
| 80 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.99037500 |
| 81 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 0.98445283 |
| 82 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.97705443 |
| 83 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.97705443 |
| 84 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.97500677 |
| 85 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.97344023 |
| 86 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 0.97138139 |
| 87 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 0.97088323 |
| 88 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.96253085 |
| 89 | AR_25329375_ChIP-Seq_VCAP_Human | 0.95855641 |
| 90 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.92726960 |
| 91 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.92624292 |
| 92 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 0.92190291 |
| 93 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.91519038 |
| 94 | E2F1_17053090_ChIP-ChIP_MCF-7_Human | 0.89947503 |
| 95 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 0.89191265 |
| 96 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.88371671 |
| 97 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.87823216 |
| 98 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 0.86919967 |
| 99 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 0.86808211 |
| 100 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.86720694 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001529_abnormal_vocalization | 3.19553356 |
| 2 | MP0009697_abnormal_copulation | 3.05103415 |
| 3 | MP0000566_synostosis | 2.84660888 |
| 4 | MP0003136_yellow_coat_color | 2.42564586 |
| 5 | MP0003567_abnormal_fetal_cardiomyocyte | 2.34616180 |
| 6 | MP0003806_abnormal_nucleotide_metabolis | 2.32979139 |
| 7 | MP0009379_abnormal_foot_pigmentation | 2.30564430 |
| 8 | MP0001661_extended_life_span | 2.28927099 |
| 9 | MP0008058_abnormal_DNA_repair | 2.21137355 |
| 10 | MP0006072_abnormal_retinal_apoptosis | 2.20040270 |
| 11 | MP0003011_delayed_dark_adaptation | 2.10687489 |
| 12 | MP0001984_abnormal_olfaction | 2.07803378 |
| 13 | MP0008995_early_reproductive_senescence | 2.01801286 |
| 14 | MP0004133_heterotaxia | 1.97663588 |
| 15 | MP0001905_abnormal_dopamine_level | 1.89699130 |
| 16 | MP0003880_abnormal_central_pattern | 1.79078784 |
| 17 | MP0006276_abnormal_autonomic_nervous | 1.78097662 |
| 18 | MP0002837_dystrophic_cardiac_calcinosis | 1.77593568 |
| 19 | MP0005551_abnormal_eye_electrophysiolog | 1.76833597 |
| 20 | MP0004043_abnormal_pH_regulation | 1.74399868 |
| 21 | MP0005646_abnormal_pituitary_gland | 1.74320814 |
| 22 | MP0003786_premature_aging | 1.71140594 |
| 23 | MP0001968_abnormal_touch/_nociception | 1.68532407 |
| 24 | MP0005410_abnormal_fertilization | 1.65589959 |
| 25 | MP0005253_abnormal_eye_physiology | 1.64326878 |
| 26 | MP0002938_white_spotting | 1.59272018 |
| 27 | MP0002736_abnormal_nociception_after | 1.58583541 |
| 28 | MP0002160_abnormal_reproductive_system | 1.56612363 |
| 29 | MP0008877_abnormal_DNA_methylation | 1.56113478 |
| 30 | MP0002822_catalepsy | 1.54957593 |
| 31 | MP0000631_abnormal_neuroendocrine_gland | 1.54057366 |
| 32 | MP0001324_abnormal_eye_pigmentation | 1.47261909 |
| 33 | MP0000516_abnormal_urinary_system | 1.46412329 |
| 34 | MP0005367_renal/urinary_system_phenotyp | 1.46412329 |
| 35 | MP0005394_taste/olfaction_phenotype | 1.42801518 |
| 36 | MP0005499_abnormal_olfactory_system | 1.42801518 |
| 37 | MP0005075_abnormal_melanosome_morpholog | 1.39593269 |
| 38 | MP0003937_abnormal_limbs/digits/tail_de | 1.37229678 |
| 39 | MP0002163_abnormal_gland_morphology | 1.37202589 |
| 40 | MP0000569_abnormal_digit_pigmentation | 1.35994074 |
| 41 | MP0006035_abnormal_mitochondrial_morpho | 1.35138839 |
| 42 | MP0004145_abnormal_muscle_electrophysio | 1.34498300 |
| 43 | MP0001188_hyperpigmentation | 1.33872516 |
| 44 | MP0000372_irregular_coat_pigmentation | 1.33233019 |
| 45 | MP0002572_abnormal_emotion/affect_behav | 1.32828421 |
| 46 | MP0002909_abnormal_adrenal_gland | 1.32462103 |
| 47 | MP0010386_abnormal_urinary_bladder | 1.31674408 |
| 48 | MP0005171_absent_coat_pigmentation | 1.31288028 |
| 49 | MP0004142_abnormal_muscle_tone | 1.30424145 |
| 50 | MP0005408_hypopigmentation | 1.29937205 |
| 51 | MP0006292_abnormal_olfactory_placode | 1.29366044 |
| 52 | MP0008007_abnormal_cellular_replicative | 1.28826925 |
| 53 | MP0003137_abnormal_impulse_conducting | 1.26721778 |
| 54 | MP0009745_abnormal_behavioral_response | 1.25542396 |
| 55 | MP0008789_abnormal_olfactory_epithelium | 1.24201776 |
| 56 | MP0003186_abnormal_redox_activity | 1.23604292 |
| 57 | MP0002272_abnormal_nervous_system | 1.22075185 |
| 58 | MP0006036_abnormal_mitochondrial_physio | 1.21729767 |
| 59 | MP0005379_endocrine/exocrine_gland_phen | 1.20059479 |
| 60 | MP0002638_abnormal_pupillary_reflex | 1.19874413 |
| 61 | MP0004885_abnormal_endolymph | 1.18571502 |
| 62 | MP0005389_reproductive_system_phenotype | 1.18182839 |
| 63 | MP0001440_abnormal_grooming_behavior | 1.15274392 |
| 64 | MP0000778_abnormal_nervous_system | 1.14878472 |
| 65 | MP0003718_maternal_effect | 1.12923865 |
| 66 | MP0009046_muscle_twitch | 1.09968940 |
| 67 | MP0000049_abnormal_middle_ear | 1.07182244 |
| 68 | MP0002735_abnormal_chemical_nociception | 1.03775264 |
| 69 | MP0005084_abnormal_gallbladder_morpholo | 1.01754237 |
| 70 | MP0003635_abnormal_synaptic_transmissio | 1.01351058 |
| 71 | MP0004019_abnormal_vitamin_homeostasis | 0.99871955 |
| 72 | MP0002102_abnormal_ear_morphology | 0.97073118 |
| 73 | MP0003698_abnormal_male_reproductive | 0.97052983 |
| 74 | MP0008932_abnormal_embryonic_tissue | 0.94707521 |
| 75 | MP0000013_abnormal_adipose_tissue | 0.93755479 |
| 76 | MP0005187_abnormal_penis_morphology | 0.92464004 |
| 77 | MP0002234_abnormal_pharynx_morphology | 0.92383955 |
| 78 | MP0005195_abnormal_posterior_eye | 0.90061717 |
| 79 | MP0002210_abnormal_sex_determination | 0.89354617 |
| 80 | MP0005448_abnormal_energy_balance | 0.87636305 |
| 81 | MP0001764_abnormal_homeostasis | 0.87635132 |
| 82 | MP0008875_abnormal_xenobiotic_pharmacok | 0.87384037 |
| 83 | MP0001929_abnormal_gametogenesis | 0.87363581 |
| 84 | MP0002095_abnormal_skin_pigmentation | 0.87344521 |
| 85 | MP0002063_abnormal_learning/memory/cond | 0.85752671 |
| 86 | MP0004858_abnormal_nervous_system | 0.85477373 |
| 87 | MP0002557_abnormal_social/conspecific_i | 0.82942778 |
| 88 | MP0001485_abnormal_pinna_reflex | 0.81243534 |
| 89 | MP0010094_abnormal_chromosome_stability | 0.79910924 |
| 90 | MP0004085_abnormal_heartbeat | 0.77475585 |
| 91 | MP0000653_abnormal_sex_gland | 0.76705580 |
| 92 | MP0000343_altered_response_to | 0.76539905 |
| 93 | MP0009250_abnormal_appendicular_skeleto | 0.76255404 |
| 94 | MP0004957_abnormal_blastocyst_morpholog | 0.75987487 |
| 95 | MP0002734_abnormal_mechanical_nocicepti | 0.75773560 |
| 96 | MP0001486_abnormal_startle_reflex | 0.75274002 |
| 97 | MP0000026_abnormal_inner_ear | 0.74561159 |
| 98 | MP0001919_abnormal_reproductive_system | 0.74036222 |
| 99 | MP0001970_abnormal_pain_threshold | 0.74031921 |
| 100 | MP0008569_lethality_at_weaning | 0.72390257 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.83007048 |
| 2 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.51697562 |
| 3 | Abnormal respiratory motile cilium physiology (HP:0012261) | 3.99333245 |
| 4 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 3.93447708 |
| 5 | Progressive macrocephaly (HP:0004481) | 3.93156156 |
| 6 | Acute encephalopathy (HP:0006846) | 3.84210795 |
| 7 | True hermaphroditism (HP:0010459) | 3.81652642 |
| 8 | Abnormal ciliary motility (HP:0012262) | 3.80987568 |
| 9 | Mitochondrial inheritance (HP:0001427) | 3.80098287 |
| 10 | Pancreatic cysts (HP:0001737) | 3.77977620 |
| 11 | Lipid accumulation in hepatocytes (HP:0006561) | 3.57132298 |
| 12 | Molar tooth sign on MRI (HP:0002419) | 3.55241483 |
| 13 | Abnormality of midbrain morphology (HP:0002418) | 3.55241483 |
| 14 | Pancreatic fibrosis (HP:0100732) | 3.54578431 |
| 15 | Increased CSF lactate (HP:0002490) | 3.43076900 |
| 16 | Increased hepatocellular lipid droplets (HP:0006565) | 3.24399611 |
| 17 | Humeroradial synostosis (HP:0003041) | 3.18751970 |
| 18 | Synostosis involving the elbow (HP:0003938) | 3.18751970 |
| 19 | Abnormal respiratory epithelium morphology (HP:0012253) | 3.18140328 |
| 20 | Abnormal respiratory motile cilium morphology (HP:0005938) | 3.18140328 |
| 21 | Nephronophthisis (HP:0000090) | 3.14278453 |
| 22 | Rhinitis (HP:0012384) | 3.13785054 |
| 23 | Cerebral edema (HP:0002181) | 3.09166477 |
| 24 | Occipital encephalocele (HP:0002085) | 3.03893232 |
| 25 | 3-Methylglutaconic aciduria (HP:0003535) | 3.02676371 |
| 26 | Renal Fanconi syndrome (HP:0001994) | 3.01332834 |
| 27 | Type II lissencephaly (HP:0007260) | 2.99075969 |
| 28 | Hepatocellular necrosis (HP:0001404) | 2.89773236 |
| 29 | Congenital stationary night blindness (HP:0007642) | 2.88276652 |
| 30 | Hepatic necrosis (HP:0002605) | 2.82689267 |
| 31 | Short tibia (HP:0005736) | 2.78066627 |
| 32 | Fibular aplasia (HP:0002990) | 2.74910690 |
| 33 | Retinal dysplasia (HP:0007973) | 2.73270074 |
| 34 | Delayed CNS myelination (HP:0002188) | 2.71655123 |
| 35 | Cystic liver disease (HP:0006706) | 2.69223916 |
| 36 | Medial flaring of the eyebrow (HP:0010747) | 2.65323087 |
| 37 | Exercise intolerance (HP:0003546) | 2.64324907 |
| 38 | Absent/shortened dynein arms (HP:0200106) | 2.63948856 |
| 39 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.63948856 |
| 40 | Increased serum lactate (HP:0002151) | 2.62219472 |
| 41 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 2.58159468 |
| 42 | Short 1st metacarpal (HP:0010034) | 2.56971120 |
| 43 | Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026) | 2.56971120 |
| 44 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.49721045 |
| 45 | Abnormality of the 1st metacarpal (HP:0010009) | 2.48190513 |
| 46 | Short phalanx of the thumb (HP:0009660) | 2.47612501 |
| 47 | Limb dystonia (HP:0002451) | 2.45939389 |
| 48 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.45142297 |
| 49 | Chronic hepatic failure (HP:0100626) | 2.43226490 |
| 50 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 2.41634446 |
| 51 | Optic disc pallor (HP:0000543) | 2.36265258 |
| 52 | Abnormality of the anterior horn cell (HP:0006802) | 2.34812573 |
| 53 | Degeneration of anterior horn cells (HP:0002398) | 2.34812573 |
| 54 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.33443356 |
| 55 | Sclerocornea (HP:0000647) | 2.29738732 |
| 56 | Abnormal biliary tract physiology (HP:0012439) | 2.29111123 |
| 57 | Bile duct proliferation (HP:0001408) | 2.29111123 |
| 58 | Congenital hepatic fibrosis (HP:0002612) | 2.28711150 |
| 59 | Abnormal number of erythroid precursors (HP:0012131) | 2.28461511 |
| 60 | Male pseudohermaphroditism (HP:0000037) | 2.27185770 |
| 61 | Exertional dyspnea (HP:0002875) | 2.26624708 |
| 62 | Anencephaly (HP:0002323) | 2.26122193 |
| 63 | Respiratory failure (HP:0002878) | 2.21517575 |
| 64 | Lactic acidosis (HP:0003128) | 2.18120165 |
| 65 | Abnormality of the renal medulla (HP:0100957) | 2.17338875 |
| 66 | Gait imbalance (HP:0002141) | 2.17054185 |
| 67 | Cerebellar dysplasia (HP:0007033) | 2.16812632 |
| 68 | Increased muscle lipid content (HP:0009058) | 2.16542728 |
| 69 | Increased intramyocellular lipid droplets (HP:0012240) | 2.15570783 |
| 70 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.15334288 |
| 71 | Leukodystrophy (HP:0002415) | 2.11806455 |
| 72 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.11354363 |
| 73 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.05787327 |
| 74 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.05723694 |
| 75 | Congenital primary aphakia (HP:0007707) | 2.05454420 |
| 76 | Abnormality of the middle phalanges of the toes (HP:0010183) | 2.05206091 |
| 77 | Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161) | 2.02849151 |
| 78 | Decreased central vision (HP:0007663) | 2.02332264 |
| 79 | Furrowed tongue (HP:0000221) | 2.02279099 |
| 80 | Pendular nystagmus (HP:0012043) | 2.00948424 |
| 81 | Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658) | 1.98158325 |
| 82 | Meckel diverticulum (HP:0002245) | 1.97970923 |
| 83 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 1.97665409 |
| 84 | Nephrogenic diabetes insipidus (HP:0009806) | 1.96618188 |
| 85 | Colon cancer (HP:0003003) | 1.94175049 |
| 86 | Abnormality of the ileum (HP:0001549) | 1.93203408 |
| 87 | Methylmalonic acidemia (HP:0002912) | 1.87659563 |
| 88 | Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376) | 1.85277136 |
| 89 | Deformed tarsal bones (HP:0008119) | 1.83663647 |
| 90 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.83011104 |
| 91 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 1.82973950 |
| 92 | Postaxial hand polydactyly (HP:0001162) | 1.82904439 |
| 93 | Mesomelia (HP:0003027) | 1.79108281 |
| 94 | Enlarged epiphyses (HP:0010580) | 1.78315195 |
| 95 | Abolished electroretinogram (ERG) (HP:0000550) | 1.78294153 |
| 96 | Postaxial foot polydactyly (HP:0001830) | 1.78214967 |
| 97 | Lissencephaly (HP:0001339) | 1.77631382 |
| 98 | Abnormality of renal resorption (HP:0011038) | 1.76704663 |
| 99 | Macrocytic anemia (HP:0001972) | 1.76663126 |
| 100 | Chronic bronchitis (HP:0004469) | 1.76583884 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | WNK3 | 3.92878921 |
| 2 | BMPR1B | 3.72412906 |
| 3 | PNCK | 3.14365347 |
| 4 | MAP4K2 | 3.01674782 |
| 5 | BUB1 | 2.64568369 |
| 6 | TRIM28 | 2.60323411 |
| 7 | TAOK3 | 2.45640952 |
| 8 | CCNB1 | 2.40899655 |
| 9 | PINK1 | 2.39419291 |
| 10 | TLK1 | 2.29899168 |
| 11 | WEE1 | 2.29573633 |
| 12 | NME2 | 2.23912129 |
| 13 | TIE1 | 2.18639474 |
| 14 | MUSK | 2.00371322 |
| 15 | BCKDK | 1.95623920 |
| 16 | WNK4 | 1.91370621 |
| 17 | PLK4 | 1.91057425 |
| 18 | GRK1 | 1.86517408 |
| 19 | SRPK1 | 1.81882179 |
| 20 | MAPKAPK3 | 1.81698043 |
| 21 | CDK8 | 1.78897293 |
| 22 | MAPKAPK5 | 1.61214158 |
| 23 | MARK1 | 1.60756388 |
| 24 | MAP2K7 | 1.58780753 |
| 25 | MAP3K4 | 1.58015640 |
| 26 | TNIK | 1.57014303 |
| 27 | DYRK2 | 1.47333234 |
| 28 | RPS6KA5 | 1.47260442 |
| 29 | ERBB3 | 1.43411404 |
| 30 | TESK1 | 1.38363722 |
| 31 | ZAK | 1.33745429 |
| 32 | DYRK3 | 1.33035140 |
| 33 | TGFBR1 | 1.32144266 |
| 34 | EPHB1 | 1.29770736 |
| 35 | CASK | 1.25009842 |
| 36 | NEK1 | 1.23139015 |
| 37 | CSNK1G2 | 1.22295812 |
| 38 | VRK1 | 1.20957912 |
| 39 | PHKG2 | 1.18827771 |
| 40 | PHKG1 | 1.18827771 |
| 41 | MKNK1 | 1.14767138 |
| 42 | ADRBK2 | 1.10897391 |
| 43 | MAPK13 | 1.06872076 |
| 44 | MARK3 | 1.05454145 |
| 45 | TSSK6 | 1.03853032 |
| 46 | NUAK1 | 1.00712203 |
| 47 | MAPK15 | 1.00694554 |
| 48 | PRKCG | 0.90432543 |
| 49 | VRK2 | 0.87461360 |
| 50 | AKT3 | 0.87461194 |
| 51 | STK16 | 0.84430469 |
| 52 | BCR | 0.78311048 |
| 53 | RPS6KA4 | 0.76082761 |
| 54 | PAK3 | 0.74060326 |
| 55 | CSNK1G3 | 0.71246164 |
| 56 | AURKA | 0.69554103 |
| 57 | DAPK1 | 0.62759907 |
| 58 | PLK1 | 0.62091457 |
| 59 | STK4 | 0.60596813 |
| 60 | INSRR | 0.58978299 |
| 61 | PTK2B | 0.58942039 |
| 62 | NEK2 | 0.57002266 |
| 63 | PLK2 | 0.54920997 |
| 64 | DYRK1A | 0.49847052 |
| 65 | TTK | 0.48558307 |
| 66 | TEC | 0.47640836 |
| 67 | LATS1 | 0.47622926 |
| 68 | PASK | 0.47517861 |
| 69 | PDK2 | 0.46615702 |
| 70 | PRKACA | 0.44959632 |
| 71 | AURKB | 0.44823736 |
| 72 | DAPK2 | 0.43522208 |
| 73 | PBK | 0.43174110 |
| 74 | IRAK2 | 0.43001002 |
| 75 | PLK3 | 0.42789712 |
| 76 | CSNK1G1 | 0.42031558 |
| 77 | CSNK2A1 | 0.41716429 |
| 78 | OBSCN | 0.41122620 |
| 79 | MAP2K4 | 0.39524337 |
| 80 | ALK | 0.39333272 |
| 81 | MKNK2 | 0.38986658 |
| 82 | CSNK2A2 | 0.38696251 |
| 83 | CSNK1A1L | 0.37533737 |
| 84 | CAMK2A | 0.37284651 |
| 85 | STK38 | 0.37173991 |
| 86 | STK39 | 0.36553627 |
| 87 | CDK3 | 0.36319482 |
| 88 | PAK6 | 0.36110192 |
| 89 | PRKCE | 0.35874347 |
| 90 | GRK5 | 0.34477867 |
| 91 | TNK2 | 0.33589162 |
| 92 | ATR | 0.31854158 |
| 93 | PRKCI | 0.31780364 |
| 94 | TRPM7 | 0.26858776 |
| 95 | CDK14 | 0.26200590 |
| 96 | CSNK1D | 0.26100219 |
| 97 | FRK | 0.24739714 |
| 98 | PRKACB | 0.24156208 |
| 99 | PIM2 | 0.24124686 |
| 100 | BRAF | 0.23416897 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.50688596 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 4.24444710 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 4.09067320 |
| 4 | RNA polymerase_Homo sapiens_hsa03020 | 2.99081365 |
| 5 | Huntingtons disease_Homo sapiens_hsa05016 | 2.94692293 |
| 6 | Alzheimers disease_Homo sapiens_hsa05010 | 2.66138355 |
| 7 | Sulfur relay system_Homo sapiens_hsa04122 | 2.37808900 |
| 8 | Protein export_Homo sapiens_hsa03060 | 2.31679485 |
| 9 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.21559330 |
| 10 | Proteasome_Homo sapiens_hsa03050 | 2.15930916 |
| 11 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.01963156 |
| 12 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.01332503 |
| 13 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.93898211 |
| 14 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.93167139 |
| 15 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.92570043 |
| 16 | Homologous recombination_Homo sapiens_hsa03440 | 1.89800311 |
| 17 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.86746926 |
| 18 | Phototransduction_Homo sapiens_hsa04744 | 1.78395498 |
| 19 | Nicotine addiction_Homo sapiens_hsa05033 | 1.76708712 |
| 20 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.60196313 |
| 21 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.56192119 |
| 22 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.55941982 |
| 23 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.55307876 |
| 24 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.55078774 |
| 25 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.51514304 |
| 26 | DNA replication_Homo sapiens_hsa03030 | 1.51208995 |
| 27 | Purine metabolism_Homo sapiens_hsa00230 | 1.41786381 |
| 28 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.36496006 |
| 29 | RNA degradation_Homo sapiens_hsa03018 | 1.33311917 |
| 30 | Basal transcription factors_Homo sapiens_hsa03022 | 1.30837767 |
| 31 | Spliceosome_Homo sapiens_hsa03040 | 1.21667369 |
| 32 | Peroxisome_Homo sapiens_hsa04146 | 1.16120681 |
| 33 | Mismatch repair_Homo sapiens_hsa03430 | 1.09609349 |
| 34 | RNA transport_Homo sapiens_hsa03013 | 1.09295906 |
| 35 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.08440913 |
| 36 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.07221047 |
| 37 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.02388803 |
| 38 | Base excision repair_Homo sapiens_hsa03410 | 0.94470395 |
| 39 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.94255820 |
| 40 | Metabolic pathways_Homo sapiens_hsa01100 | 0.94180858 |
| 41 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.93557184 |
| 42 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.93074572 |
| 43 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.92296795 |
| 44 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.91829475 |
| 45 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.87902034 |
| 46 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.85561276 |
| 47 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.83634274 |
| 48 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.80881869 |
| 49 | Taste transduction_Homo sapiens_hsa04742 | 0.80360176 |
| 50 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.79600194 |
| 51 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.78727511 |
| 52 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.78306570 |
| 53 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.71447796 |
| 54 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.71100063 |
| 55 | Gap junction_Homo sapiens_hsa04540 | 0.71069468 |
| 56 | Olfactory transduction_Homo sapiens_hsa04740 | 0.70211376 |
| 57 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.69892693 |
| 58 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.65177872 |
| 59 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.64005707 |
| 60 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.63713056 |
| 61 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.62721923 |
| 62 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.61578909 |
| 63 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.61170246 |
| 64 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.58128408 |
| 65 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.57291723 |
| 66 | Alcoholism_Homo sapiens_hsa05034 | 0.56383070 |
| 67 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.56169549 |
| 68 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.56015855 |
| 69 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.53338405 |
| 70 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.51433087 |
| 71 | Circadian entrainment_Homo sapiens_hsa04713 | 0.50813888 |
| 72 | GABAergic synapse_Homo sapiens_hsa04727 | 0.49771206 |
| 73 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.48830259 |
| 74 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.47601314 |
| 75 | Galactose metabolism_Homo sapiens_hsa00052 | 0.46436024 |
| 76 | Morphine addiction_Homo sapiens_hsa05032 | 0.45834424 |
| 77 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.45750333 |
| 78 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.45400513 |
| 79 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.44157182 |
| 80 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.43918076 |
| 81 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.43592478 |
| 82 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.41678531 |
| 83 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.40639910 |
| 84 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.40137673 |
| 85 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.40129703 |
| 86 | Retinol metabolism_Homo sapiens_hsa00830 | 0.39185660 |
| 87 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.39032529 |
| 88 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.38337967 |
| 89 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.35877311 |
| 90 | Cocaine addiction_Homo sapiens_hsa05030 | 0.35728508 |
| 91 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.35491645 |
| 92 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.35263293 |
| 93 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.32956136 |
| 94 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.31505233 |
| 95 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.30691161 |
| 96 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.30321046 |
| 97 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.29667414 |
| 98 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.28703571 |
| 99 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.28665079 |
| 100 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.27775432 |

