BEND5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.45082054
2energy coupled proton transport, down electrochemical gradient (GO:0015985)4.34192986
3ATP synthesis coupled proton transport (GO:0015986)4.34192986
4establishment of mitochondrion localization (GO:0051654)4.17176364
5gamma-aminobutyric acid transport (GO:0015812)4.10483900
6axonal fasciculation (GO:0007413)4.07047056
7dopamine biosynthetic process (GO:0042416)4.00527490
8negative regulation of microtubule polymerization (GO:0031115)3.94941047
9presynaptic membrane assembly (GO:0097105)3.83816032
10pyrimidine nucleobase catabolic process (GO:0006208)3.82507216
11regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.79611911
12positive regulation of mitochondrial fission (GO:0090141)3.79376953
13neuron cell-cell adhesion (GO:0007158)3.76002917
14neuron recognition (GO:0008038)3.72507774
15auditory behavior (GO:0031223)3.69868346
16nonmotile primary cilium assembly (GO:0035058)3.57578976
17protein localization to cilium (GO:0061512)3.55713497
18transmission of nerve impulse (GO:0019226)3.53700466
19synaptic vesicle maturation (GO:0016188)3.53590354
20protein polyglutamylation (GO:0018095)3.52441224
21intraciliary transport (GO:0042073)3.50709651
22dopamine transport (GO:0015872)3.48729449
23epithelial cilium movement (GO:0003351)3.47322139
24negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.38752353
25negative regulation of synaptic transmission, GABAergic (GO:0032229)3.37670926
26catecholamine transport (GO:0051937)3.34178346
27synapse assembly (GO:0007416)3.32887619
28neurofilament cytoskeleton organization (GO:0060052)3.31491825
29peptidyl-arginine omega-N-methylation (GO:0035247)3.30445766
30histone arginine methylation (GO:0034969)3.29533546
31regulation of synapse structural plasticity (GO:0051823)3.27121489
32peptidyl-arginine methylation (GO:0018216)3.26292243
33peptidyl-arginine N-methylation (GO:0035246)3.26292243
34synaptic vesicle exocytosis (GO:0016079)3.24151890
35sequestering of actin monomers (GO:0042989)3.22707882
36synaptic transmission, glutamatergic (GO:0035249)3.19236294
37substrate-independent telencephalic tangential interneuron migration (GO:0021843)3.15398785
38substrate-independent telencephalic tangential migration (GO:0021826)3.15398785
39ribosomal small subunit assembly (GO:0000028)3.14973450
40adult walking behavior (GO:0007628)3.12637370
41regulation of synaptic vesicle exocytosis (GO:2000300)3.12092731
42regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.08477066
43chaperone-mediated protein transport (GO:0072321)3.05881240
44histone H2A acetylation (GO:0043968)3.05079408
45cell migration in hindbrain (GO:0021535)3.02715487
46ionotropic glutamate receptor signaling pathway (GO:0035235)3.01868063
47viral transcription (GO:0019083)3.01266388
48response to auditory stimulus (GO:0010996)3.00716661
49retinal ganglion cell axon guidance (GO:0031290)2.99911003
50positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.99005528
51spinal cord association neuron differentiation (GO:0021527)2.98765144
52mitochondrion transport along microtubule (GO:0047497)2.98468928
53establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.98468928
54protein localization to synapse (GO:0035418)2.98178527
55layer formation in cerebral cortex (GO:0021819)2.97134125
56neurotransmitter-gated ion channel clustering (GO:0072578)2.95676515
57regulation of synaptic vesicle transport (GO:1902803)2.95042604
58positive regulation of synapse maturation (GO:0090129)2.94616858
59response to parathyroid hormone (GO:0071107)2.94104035
60GTP biosynthetic process (GO:0006183)2.93339977
61cilium movement (GO:0003341)2.93209925
62olfactory bulb development (GO:0021772)2.93182844
63positive regulation of synapse assembly (GO:0051965)2.92292250
64short-term memory (GO:0007614)2.92003092
65synaptic transmission, cholinergic (GO:0007271)2.91492573
66left/right pattern formation (GO:0060972)2.90166392
67presynaptic membrane organization (GO:0097090)2.89946323
68establishment of integrated proviral latency (GO:0075713)2.89143716
69vocalization behavior (GO:0071625)2.88320165
70neurotransmitter secretion (GO:0007269)2.88285018
71neuron-neuron synaptic transmission (GO:0007270)2.86917801
72positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145)2.86287313
73axoneme assembly (GO:0035082)2.83176380
74neuronal ion channel clustering (GO:0045161)2.81953537
75translational termination (GO:0006415)2.81941702
76mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.81941640
77neuromuscular synaptic transmission (GO:0007274)2.81204248
78calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.81043968
79embryonic foregut morphogenesis (GO:0048617)2.79576530
80ribosomal small subunit biogenesis (GO:0042274)2.76909118
81glycosphingolipid biosynthetic process (GO:0006688)2.76071325
82neuronal action potential propagation (GO:0019227)2.75888222
83regulation of short-term neuronal synaptic plasticity (GO:0048172)2.74811335
84regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.74100116
85regulation of glutamate receptor signaling pathway (GO:1900449)2.73436591
86head development (GO:0060322)2.72864060
87membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.72188161
88nucleobase catabolic process (GO:0046113)2.71302533
89epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.70793218
90catechol-containing compound biosynthetic process (GO:0009713)2.70237525
91catecholamine biosynthetic process (GO:0042423)2.70237525
92regulation of cilium movement (GO:0003352)2.69192012
93positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.67654805
94cytidine deamination (GO:0009972)2.66099271
95cytidine metabolic process (GO:0046087)2.66099271
96cytidine catabolic process (GO:0006216)2.66099271
97positive regulation of gastrulation (GO:2000543)2.62512440
98limb bud formation (GO:0060174)2.62477076
99respiratory electron transport chain (GO:0022904)2.61369552
100somite development (GO:0061053)2.60320568
101glutamate receptor signaling pathway (GO:0007215)2.60041252
102dendritic spine morphogenesis (GO:0060997)2.59961221
103regulation of respiratory system process (GO:0044065)2.59910490
104regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.59544080
105postsynaptic membrane organization (GO:0001941)2.58338270
106central nervous system myelination (GO:0022010)2.58160136
107axon ensheathment in central nervous system (GO:0032291)2.58160136
108electron transport chain (GO:0022900)2.57436222
109cytoskeleton-dependent intracellular transport (GO:0030705)2.57164130
110cerebral cortex radially oriented cell migration (GO:0021799)2.57147886
111UTP biosynthetic process (GO:0006228)2.56661719
112ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162.56360261
113forebrain neuron differentiation (GO:0021879)2.55937462
114regulation of feeding behavior (GO:0060259)2.55568398
115neural tube formation (GO:0001841)2.55227374
116regulation of microtubule-based movement (GO:0060632)2.55106497
117cellular protein complex disassembly (GO:0043624)2.54610702
118behavioral response to ethanol (GO:0048149)2.54338870
119startle response (GO:0001964)2.54042222
120dendrite development (GO:0016358)2.53968717
121spinal cord development (GO:0021510)2.53253069
122cilium morphogenesis (GO:0060271)2.52852080
123positive regulation of dendritic spine morphogenesis (GO:0061003)2.52185688
124protein-cofactor linkage (GO:0018065)2.50162733
125negative regulation of telomere maintenance (GO:0032205)2.50116793
126G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.49411221
127hippocampus development (GO:0021766)2.49347529
128regulation of catecholamine metabolic process (GO:0042069)2.49082574
129regulation of dopamine metabolic process (GO:0042053)2.49082574
130cilium organization (GO:0044782)2.48873451
131cilium assembly (GO:0042384)2.47952463
132nephron epithelium morphogenesis (GO:0072088)2.46485598
133nephron tubule morphogenesis (GO:0072078)2.46485598
134positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.46461358
135cotranslational protein targeting to membrane (GO:0006613)2.46446505
136translational elongation (GO:0006414)2.46273433
137regulation of synapse assembly (GO:0051963)2.46125916
138positive regulation of cellular response to oxidative stress (GO:1900409)2.45260674
139positive regulation of response to oxidative stress (GO:1902884)2.45260674
140regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.42411232
141protein complex disassembly (GO:0043241)2.42019204
142SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.40129303
143guanosine-containing compound biosynthetic process (GO:1901070)2.38891665
144renal tubule morphogenesis (GO:0061333)2.38803450
145protein targeting to ER (GO:0045047)2.37358311
146negative regulation of mesenchymal cell apoptotic process (GO:2001054)2.36681597
147central nervous system projection neuron axonogenesis (GO:0021952)2.35744818
148viral life cycle (GO:0019058)2.35389933
149macromolecular complex disassembly (GO:0032984)2.35112472
150positive regulation of inositol phosphate biosynthetic process (GO:0060732)2.34427573
151cranial nerve morphogenesis (GO:0021602)2.34315358
152opioid receptor signaling pathway (GO:0038003)2.29787513
153behavioral response to nicotine (GO:0035095)2.29513239
154regulation of mesenchymal cell apoptotic process (GO:2001053)2.29016073
155negative regulation of RNA splicing (GO:0033119)2.29000986
156serotonin metabolic process (GO:0042428)2.28451492
157nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.27805760
158mitochondrial respiratory chain complex I assembly (GO:0032981)2.27146426
159NADH dehydrogenase complex assembly (GO:0010257)2.27146426
160mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.27146426
161regulation of dopamine secretion (GO:0014059)2.26341790
162positive regulation of protein homodimerization activity (GO:0090073)2.25915137
163regulation of mRNA splicing, via spliceosome (GO:0048024)2.25061208
164purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.24245862
165establishment of protein localization to endoplasmic reticulum (GO:0072599)2.24223691
166hindbrain development (GO:0030902)2.23123724
167response to pheromone (GO:0019236)2.22993794
168cullin deneddylation (GO:0010388)2.22780989
169righting reflex (GO:0060013)2.21971210
170protein complex biogenesis (GO:0070271)2.21208990
171mechanosensory behavior (GO:0007638)2.19259893
172regulation of synapse maturation (GO:0090128)2.19127790
173translational initiation (GO:0006413)2.18644046
174dopaminergic neuron differentiation (GO:0071542)2.18540242
175protein localization to endoplasmic reticulum (GO:0070972)2.17490288
176mitochondrial respiratory chain complex assembly (GO:0033108)2.16992133

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.29687246
2RBPJ_22232070_ChIP-Seq_NCS_Mouse2.90949455
3EZH2_27304074_Chip-Seq_ESCs_Mouse2.88359925
4SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.86165833
5NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.85115375
6BMI1_23680149_ChIP-Seq_NPCS_Mouse2.84183044
7JARID2_20064375_ChIP-Seq_MESCs_Mouse2.78819632
8CBX2_27304074_Chip-Seq_ESCs_Mouse2.35291737
9HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.33078858
10GBX2_23144817_ChIP-Seq_PC3_Human2.26916207
11CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.26739120
12JARID2_20075857_ChIP-Seq_MESCs_Mouse2.21574648
13RNF2_27304074_Chip-Seq_NSC_Mouse2.17658453
14TAF15_26573619_Chip-Seq_HEK293_Human2.14871487
15SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.14243048
16EED_16625203_ChIP-ChIP_MESCs_Mouse2.13306989
17TP63_19390658_ChIP-ChIP_HaCaT_Human2.11680929
18GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.10547375
19EZH2_18974828_ChIP-Seq_MESCs_Mouse2.06136733
20RNF2_18974828_ChIP-Seq_MESCs_Mouse2.06136733
21SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.03817233
22TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.03182614
23TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.00249653
24PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.99206062
25ZNF274_21170338_ChIP-Seq_K562_Hela1.96987199
26SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.91929735
27* CTBP2_25329375_ChIP-Seq_LNCAP_Human1.86637729
28SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.84357068
29SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.79884907
30RNF2_27304074_Chip-Seq_ESCs_Mouse1.79221357
31SUZ12_27294783_Chip-Seq_ESCs_Mouse1.78932696
32REST_21632747_ChIP-Seq_MESCs_Mouse1.75156089
33EZH2_27294783_Chip-Seq_ESCs_Mouse1.68991322
34GABP_17652178_ChIP-ChIP_JURKAT_Human1.64993133
35E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.64501279
36REST_18959480_ChIP-ChIP_MESCs_Mouse1.58039336
37KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.56934922
38FUS_26573619_Chip-Seq_HEK293_Human1.55886996
39ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.53589782
40MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.52796326
41MTF2_20144788_ChIP-Seq_MESCs_Mouse1.51700402
42RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.42568195
43IKZF1_21737484_ChIP-ChIP_HCT116_Human1.40996977
44* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.39679686
45THAP11_20581084_ChIP-Seq_MESCs_Mouse1.39308009
46CIITA_25753668_ChIP-Seq_RAJI_Human1.37426097
47CTBP1_25329375_ChIP-Seq_LNCAP_Human1.35445448
48ZFP281_18757296_ChIP-ChIP_E14_Mouse1.34911873
49* TTF2_22483619_ChIP-Seq_HELA_Human1.34498416
50IRF1_19129219_ChIP-ChIP_H3396_Human1.33519496
51EST1_17652178_ChIP-ChIP_JURKAT_Human1.32736257
52ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.30143101
53STAT6_21828071_ChIP-Seq_BEAS2B_Human1.29775301
54TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.29728315
55POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.29728315
56RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.27764121
57ETS1_20019798_ChIP-Seq_JURKAT_Human1.27657184
58RING1B_27294783_Chip-Seq_ESCs_Mouse1.26731716
59CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.25834760
60MYC_18555785_ChIP-Seq_MESCs_Mouse1.23191410
61HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.22707570
62GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.22299746
63RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.21599190
64DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.21298837
65RING1B_27294783_Chip-Seq_NPCs_Mouse1.20612121
66POU5F1_16153702_ChIP-ChIP_HESCs_Human1.20586054
67SMAD4_21799915_ChIP-Seq_A2780_Human1.20160980
68* XRN2_22483619_ChIP-Seq_HELA_Human1.20021669
69CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.19578832
70DROSHA_22980978_ChIP-Seq_HELA_Human1.19306247
71EWS_26573619_Chip-Seq_HEK293_Human1.18567029
72* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.16116828
73ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.15902617
74ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.15190553
75IGF1R_20145208_ChIP-Seq_DFB_Human1.14747236
76MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.14201494
77SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.12806180
78P300_19829295_ChIP-Seq_ESCs_Human1.12689500
79UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.12258923
80TOP2B_26459242_ChIP-Seq_MCF-7_Human1.10823882
81RARB_27405468_Chip-Seq_BRAIN_Mouse1.10514078
82SOX2_16153702_ChIP-ChIP_HESCs_Human1.10191517
83ZFP57_27257070_Chip-Seq_ESCs_Mouse1.09357380
84POU3F1_26484290_ChIP-Seq_ESCss_Mouse1.09354413
85OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.08777555
86AR_21572438_ChIP-Seq_LNCaP_Human1.08044449
87HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.07453101
88FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.07149537
89MYC_19079543_ChIP-ChIP_MESCs_Mouse1.07120346
90YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.07076662
91KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.07051800
92TP53_22573176_ChIP-Seq_HFKS_Human1.06825013
93* AR_25329375_ChIP-Seq_VCAP_Human1.06770915
94GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.05873349
95PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.03960927
96MYC_18940864_ChIP-ChIP_HL60_Human1.03745683
97ETV2_25802403_ChIP-Seq_MESCs_Mouse1.03192270
98IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.01582005
99CBP_20019798_ChIP-Seq_JUKART_Human1.01582005
100SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.01103438
101* RUNX2_22187159_ChIP-Seq_PCA_Human1.00212853
102WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.99609719
103EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.98637314
104TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98023707
105JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.97724945
106CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.96695786
107PIAS1_25552417_ChIP-Seq_VCAP_Human0.96438490
108TAL1_26923725_Chip-Seq_HPCs_Mouse0.95106220
109P53_22127205_ChIP-Seq_FIBROBLAST_Human0.94660802
110KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.94540512
111SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.94448412
112CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.92267001
113NR3C1_21868756_ChIP-Seq_MCF10A_Human0.91871317
114MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.91729600
115SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.91440060
116KLF5_20875108_ChIP-Seq_MESCs_Mouse0.90522842
117SOX2_18555785_ChIP-Seq_MESCs_Mouse0.90521652
118STAT3_23295773_ChIP-Seq_U87_Human0.89967764
119* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.89881752
120E2F1_17053090_ChIP-ChIP_MCF-7_Human0.89819724
121CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.89140755
122SOX2_21211035_ChIP-Seq_LN229_Gbm0.88974205
123SMAD3_21741376_ChIP-Seq_EPCs_Human0.88451054
124CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.88152339
125REST_19997604_ChIP-ChIP_NEURONS_Mouse0.87973199
126SOX9_26525672_Chip-Seq_HEART_Mouse0.87779852
127MYC_22102868_ChIP-Seq_BL_Human0.87368763
128MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.87308415
129VDR_22108803_ChIP-Seq_LS180_Human0.86237675
130POU3F2_20337985_ChIP-ChIP_501MEL_Human0.86159302
131TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.86103936
132TP53_20018659_ChIP-ChIP_R1E_Mouse0.86091193
133TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.86006713
134TCF4_23295773_ChIP-Seq_U87_Human0.85461355
135GATA1_26923725_Chip-Seq_HPCs_Mouse0.85010525
136CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.84761351
137NCOR_22424771_ChIP-Seq_293T_Human0.84061402
138SETDB1_19884257_ChIP-Seq_MESCs_Mouse0.83621443
139JUN_21703547_ChIP-Seq_K562_Human0.82045571

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003122_maternal_imprinting4.34283098
2MP0003121_genomic_imprinting3.08374237
3MP0003880_abnormal_central_pattern2.96535371
4MP0006276_abnormal_autonomic_nervous2.92753037
5MP0005423_abnormal_somatic_nervous2.86530609
6MP0003123_paternal_imprinting2.61205870
7MP0004859_abnormal_synaptic_plasticity2.54676971
8MP0000778_abnormal_nervous_system2.39302373
9MP0001905_abnormal_dopamine_level2.31155095
10MP0002822_catalepsy2.26352561
11MP0001529_abnormal_vocalization2.20431895
12MP0003635_abnormal_synaptic_transmissio2.15544066
13MP0003787_abnormal_imprinting2.12564812
14MP0001968_abnormal_touch/_nociception2.12113985
15MP0004270_analgesia1.98684203
16MP0006292_abnormal_olfactory_placode1.93515631
17MP0003315_abnormal_perineum_morphology1.90009153
18MP0002063_abnormal_learning/memory/cond1.89373437
19MP0002102_abnormal_ear_morphology1.85461434
20MP0003119_abnormal_digestive_system1.80088157
21MP0008961_abnormal_basal_metabolism1.78127313
22MP0002572_abnormal_emotion/affect_behav1.74289882
23MP0000631_abnormal_neuroendocrine_gland1.71059619
24MP0002184_abnormal_innervation1.68688154
25MP0000537_abnormal_urethra_morphology1.66382468
26MP0002751_abnormal_autonomic_nervous1.63999586
27MP0009745_abnormal_behavioral_response1.62355675
28MP0002557_abnormal_social/conspecific_i1.57671949
29MP0003942_abnormal_urinary_system1.56718129
30MP0004133_heterotaxia1.55253755
31MP0002064_seizures1.51100369
32MP0002736_abnormal_nociception_after1.50235444
33MP0002734_abnormal_mechanical_nocicepti1.47996704
34MP0002067_abnormal_sensory_capabilities1.46041971
35MP0001486_abnormal_startle_reflex1.42385549
36MP0005084_abnormal_gallbladder_morpholo1.40634104
37MP0000538_abnormal_urinary_bladder1.40355348
38MP0005551_abnormal_eye_electrophysiolog1.39999604
39MP0009379_abnormal_foot_pigmentation1.37453321
40MP0005645_abnormal_hypothalamus_physiol1.34893854
41MP0002909_abnormal_adrenal_gland1.34457769
42MP0008789_abnormal_olfactory_epithelium1.33645179
43MP0001188_hyperpigmentation1.33294881
44MP0005394_taste/olfaction_phenotype1.31526936
45MP0005499_abnormal_olfactory_system1.31526936
46MP0004924_abnormal_behavior1.28294443
47MP0005386_behavior/neurological_phenoty1.28294443
48MP0001485_abnormal_pinna_reflex1.26111919
49MP0005646_abnormal_pituitary_gland1.25117899
50MP0002234_abnormal_pharynx_morphology1.24479740
51MP0008995_early_reproductive_senescence1.23321912
52MP0001440_abnormal_grooming_behavior1.21713310
53MP0000534_abnormal_ureter_morphology1.20116746
54MP0002735_abnormal_chemical_nociception1.19495618
55MP0003861_abnormal_nervous_system1.19344955
56MP0008877_abnormal_DNA_methylation1.18811971
57MP0003938_abnormal_ear_development1.18476329
58MP0003283_abnormal_digestive_organ1.18441525
59MP0000049_abnormal_middle_ear1.17952277
60MP0010030_abnormal_orbit_morphology1.17227926
61MP0002163_abnormal_gland_morphology1.17223884
62MP0004147_increased_porphyrin_level1.17199260
63MP0003890_abnormal_embryonic-extraembry1.17084373
64MP0002733_abnormal_thermal_nociception1.17021730
65MP0001293_anophthalmia1.16883808
66MP0004811_abnormal_neuron_physiology1.16806295
67MP0005253_abnormal_eye_physiology1.15018080
68MP0001984_abnormal_olfaction1.12658560
69MP0003385_abnormal_body_wall1.11210680
70MP0004272_abnormal_basement_membrane1.09899842
71MP0002837_dystrophic_cardiac_calcinosis1.09251416
72MP0002152_abnormal_brain_morphology1.09145738
73MP0002653_abnormal_ependyma_morphology1.08296065
74MP0004043_abnormal_pH_regulation1.05974932
75MP0000026_abnormal_inner_ear1.04443400
76MP0004858_abnormal_nervous_system1.00452836
77MP0000751_myopathy1.00097938
78MP0002272_abnormal_nervous_system0.99736617
79MP0003136_yellow_coat_color0.98992434
80MP0002876_abnormal_thyroid_physiology0.98351034
81MP0002882_abnormal_neuron_morphology0.98248065
82MP0000955_abnormal_spinal_cord0.97784956
83MP0009046_muscle_twitch0.96205997
84MP0001963_abnormal_hearing_physiology0.96005270
85MP0002282_abnormal_trachea_morphology0.95897095
86MP0004742_abnormal_vestibular_system0.95148961
87MP0001502_abnormal_circadian_rhythm0.94820733
88MP0005195_abnormal_posterior_eye0.93596204
89MP0006072_abnormal_retinal_apoptosis0.90365844
90MP0004142_abnormal_muscle_tone0.89529595
91MP0003115_abnormal_respiratory_system0.89089306
92MP0004484_altered_response_of0.88658510
93MP0002066_abnormal_motor_capabilities/c0.88159561
94MP0002928_abnormal_bile_duct0.87757911
95MP0001970_abnormal_pain_threshold0.85438597
96MP0002938_white_spotting0.85275981
97MP0008569_lethality_at_weaning0.84204683
98MP0002233_abnormal_nose_morphology0.83861313
99MP0000462_abnormal_digestive_system0.82568848
100MP0002752_abnormal_somatic_nervous0.82541773
101MP0005187_abnormal_penis_morphology0.82203760
102MP0002081_perinatal_lethality0.80933846
103MP0004233_abnormal_muscle_weight0.80653955
104MP0003567_abnormal_fetal_cardiomyocyte0.80622222
105MP0003646_muscle_fatigue0.79977095
106MP0004885_abnormal_endolymph0.79924263
107MP0003221_abnormal_cardiomyocyte_apopto0.79649395
108MP0002638_abnormal_pupillary_reflex0.78987057
109MP0003879_abnormal_hair_cell0.78911674
110MP0002229_neurodegeneration0.78669221
111MP0001286_abnormal_eye_development0.77638508
112MP0003137_abnormal_impulse_conducting0.77397767
113MP0000569_abnormal_digit_pigmentation0.77354982
114MP0002116_abnormal_craniofacial_bone0.76518430
115MP0004085_abnormal_heartbeat0.75393639
116MP0002932_abnormal_joint_morphology0.75371768
117MP0001501_abnormal_sleep_pattern0.75233509
118MP0003011_delayed_dark_adaptation0.75196646
119MP0002069_abnormal_eating/drinking_beha0.74450052
120MP0000566_synostosis0.74070380
121MP0010386_abnormal_urinary_bladder0.72485613
122MP0005391_vision/eye_phenotype0.71438526
123MP0005377_hearing/vestibular/ear_phenot0.71309540
124MP0003878_abnormal_ear_physiology0.71309540
125MP0003633_abnormal_nervous_system0.71131069
126MP0001986_abnormal_taste_sensitivity0.71113634
127MP0005248_abnormal_Harderian_gland0.69629786

Predicted human phenotypes

RankGene SetZ-score
1Limb dystonia (HP:0002451)4.16712640
2Medial flaring of the eyebrow (HP:0010747)3.79947447
3Congenital primary aphakia (HP:0007707)3.67407223
4Abnormality of midbrain morphology (HP:0002418)3.62993547
5Molar tooth sign on MRI (HP:0002419)3.62993547
6Pancreatic fibrosis (HP:0100732)3.55684749
7Nephrogenic diabetes insipidus (HP:0009806)3.53783643
8Failure to thrive in infancy (HP:0001531)3.34727834
9Pancreatic cysts (HP:0001737)3.19073332
10Acute necrotizing encephalopathy (HP:0006965)3.17218679
11Amblyopia (HP:0000646)3.15628979
12Nephronophthisis (HP:0000090)3.14422258
13High anterior hairline (HP:0009890)3.08347086
14Abnormal number of incisors (HP:0011064)3.01319759
15Abnormal mitochondria in muscle tissue (HP:0008316)2.98858818
16Polyphagia (HP:0002591)2.97748257
17Agammaglobulinemia (HP:0004432)2.91707027
18Vaginal atresia (HP:0000148)2.86905055
19Increased circulating renin level (HP:0000848)2.86891835
20Genital tract atresia (HP:0001827)2.86155369
21Focal motor seizures (HP:0011153)2.84488772
22Mitochondrial inheritance (HP:0001427)2.79026528
23Abnormal pancreas size (HP:0012094)2.76271223
24Chronic hepatic failure (HP:0100626)2.75404958
25Agitation (HP:0000713)2.73941452
26Hypomagnesemia (HP:0002917)2.73026191
27Abnormality of magnesium homeostasis (HP:0004921)2.71607903
28Specific learning disability (HP:0001328)2.68845884
29Visual hallucinations (HP:0002367)2.68284625
30Amyotrophic lateral sclerosis (HP:0007354)2.66350299
31Drooling (HP:0002307)2.66342422
32Progressive macrocephaly (HP:0004481)2.64934043
33Poor suck (HP:0002033)2.64093335
34Pachygyria (HP:0001302)2.61096737
35Abnormal hair whorl (HP:0010721)2.59728599
36Hypercalciuria (HP:0002150)2.58734741
37Myokymia (HP:0002411)2.57647224
38Abnormal eating behavior (HP:0100738)2.56208400
39Atonic seizures (HP:0010819)2.55646158
40Poor coordination (HP:0002370)2.53382651
41Bicornuate uterus (HP:0000813)2.52954670
42Anencephaly (HP:0002323)2.52640681
43Abnormality of the corticospinal tract (HP:0002492)2.50455269
44Abnormality of the renal medulla (HP:0100957)2.47432933
45Acute encephalopathy (HP:0006846)2.45884053
46Metabolic alkalosis (HP:0200114)2.45243554
47Hypoplasia of the brainstem (HP:0002365)2.42824190
48Aplasia/Hypoplasia of the brainstem (HP:0007362)2.42824190
49Excessive salivation (HP:0003781)2.42743432
50Hyperactive renin-angiotensin system (HP:0000841)2.41052164
51Increased CSF lactate (HP:0002490)2.39023663
52Hyperphosphaturia (HP:0003109)2.38492133
53Abnormality of the labia minora (HP:0012880)2.37900476
54Cystic liver disease (HP:0006706)2.36764800
55Hyperventilation (HP:0002883)2.34489349
56Occipital encephalocele (HP:0002085)2.34197275
57Spastic tetraplegia (HP:0002510)2.29502829
58Polyuria (HP:0000103)2.29123728
59Septo-optic dysplasia (HP:0100842)2.22838037
60Sclerocornea (HP:0000647)2.22795783
61Degeneration of the lateral corticospinal tracts (HP:0002314)2.21901942
62Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.21901942
63Broad-based gait (HP:0002136)2.21601813
64Postaxial hand polydactyly (HP:0001162)2.21388193
65Gout (HP:0001997)2.20060375
66Hyperglycinemia (HP:0002154)2.19609894
67Anterior segment dysgenesis (HP:0007700)2.14567369
68Broad foot (HP:0001769)2.11598983
69Optic nerve hypoplasia (HP:0000609)2.11242885
70Sleep apnea (HP:0010535)2.10539235
71Oligodactyly (hands) (HP:0001180)2.10537384
72Hepatoblastoma (HP:0002884)2.08169591
73Morphological abnormality of the middle ear (HP:0008609)2.07236211
74Hypothermia (HP:0002045)2.05811796
75Absent speech (HP:0001344)2.05184661
76Cortical dysplasia (HP:0002539)2.04830166
77Progressive cerebellar ataxia (HP:0002073)2.04057011
78Postaxial foot polydactyly (HP:0001830)2.04028308
79Hepatocellular necrosis (HP:0001404)2.03768061
80Pendular nystagmus (HP:0012043)2.03139319
81Rimmed vacuoles (HP:0003805)2.00456703
82Rib fusion (HP:0000902)2.00126406
83Spastic gait (HP:0002064)1.99853105
84Hypoventilation (HP:0002791)1.99308359
85Polydipsia (HP:0001959)1.97958840
86Abnormal drinking behavior (HP:0030082)1.97958840
87Abnormality of renin-angiotensin system (HP:0000847)1.97244588
88Chronic sinusitis (HP:0011109)1.97059203
89Metaphyseal dysplasia (HP:0100255)1.96716893
90Colon cancer (HP:0003003)1.96552112
91Neuroendocrine neoplasm (HP:0100634)1.96199473
92Morphological abnormality of the pyramidal tract (HP:0002062)1.95901218
93Generalized tonic-clonic seizures (HP:0002069)1.94897790
94Exotropia (HP:0000577)1.93715569
95Abnormal respiratory epithelium morphology (HP:0012253)1.93677989
96Abnormal respiratory motile cilium morphology (HP:0005938)1.93677989
97Renal hypoplasia (HP:0000089)1.93300748
98Increased hepatocellular lipid droplets (HP:0006565)1.93235639
99Lissencephaly (HP:0001339)1.92382169
100Abnormal urine output (HP:0012590)1.92372982
101Hypsarrhythmia (HP:0002521)1.91068952
102Decreased testicular size (HP:0008734)1.90942110
103Aplasia/Hypoplasia of the tongue (HP:0010295)1.89593500
104Retinal dysplasia (HP:0007973)1.88542086
105Esotropia (HP:0000565)1.88276780
106Micropenis (HP:0000054)1.88208426
107Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.87795635
108Short 4th metacarpal (HP:0010044)1.87795635
109Congenital stationary night blindness (HP:0007642)1.86273695
110Increased serum pyruvate (HP:0003542)1.85482839
111Abnormality of glycolysis (HP:0004366)1.85482839
112Optic nerve coloboma (HP:0000588)1.85204326
113Epileptiform EEG discharges (HP:0011182)1.85134361
114Aplasia/Hypoplasia of the lens (HP:0008063)1.84805152
115Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.84476942
116EEG with generalized epileptiform discharges (HP:0011198)1.83446605
117Growth hormone deficiency (HP:0000824)1.83138548
118Narrow nasal bridge (HP:0000446)1.82895863
119Tubulointerstitial nephritis (HP:0001970)1.82822826
120Abnormal ciliary motility (HP:0012262)1.82740936
121Hemiparesis (HP:0001269)1.82267286
122Type II lissencephaly (HP:0007260)1.80748741
123Gastrointestinal stroma tumor (HP:0100723)1.80324552
124Progressive inability to walk (HP:0002505)1.79360456
125Left ventricular hypertrophy (HP:0001712)1.78869666
126Abnormal respiratory motile cilium physiology (HP:0012261)1.78486969
127Thyroid-stimulating hormone excess (HP:0002925)1.78358127
128Generalized hypotonia (HP:0001290)1.78285545
129Absence seizures (HP:0002121)1.77884955
130Hepatic necrosis (HP:0002605)1.77797579
131Dialeptic seizures (HP:0011146)1.77490546
132Hypokalemic alkalosis (HP:0001949)1.77383361
133Congenital hepatic fibrosis (HP:0002612)1.76994494
134Preaxial hand polydactyly (HP:0001177)1.76941159
135Epileptic encephalopathy (HP:0200134)1.76912770
136Abnormal urine phosphate concentration (HP:0012599)1.76578359
137Sacral dimple (HP:0000960)1.76501296
138Truncus arteriosus (HP:0001660)1.75730043
139Focal seizures (HP:0007359)1.75380972
140Shoulder girdle muscle weakness (HP:0003547)1.75015880
141Pheochromocytoma (HP:0002666)1.72809233
142Abnormality of renal excretion (HP:0011036)1.71627696
143Hyperaldosteronism (HP:0000859)1.71419755
144Atrioventricular canal defect (HP:0006695)1.71143695
145Tetany (HP:0001281)1.69584000
146Abnormality of calcium-phosphate metabolism (HP:0100530)1.67445422
147Partial agenesis of the corpus callosum (HP:0001338)1.67295611
148Hypokalemia (HP:0002900)1.66003020
149Renal Fanconi syndrome (HP:0001994)1.65999737
150True hermaphroditism (HP:0010459)1.65781241
151Febrile seizures (HP:0002373)1.65770840
152Hyperthyroidism (HP:0000836)1.65569338
153Narrow forehead (HP:0000341)1.64014664
154Nasal speech (HP:0001611)1.62715310
155Urinary urgency (HP:0000012)1.61924559
156Gait imbalance (HP:0002141)1.61730380
157Heterochromia iridis (HP:0001100)1.60288171
158Abnormality of the intervertebral disk (HP:0005108)1.59120265
159Autism (HP:0000717)1.59036301
160Decreased circulating renin level (HP:0003351)1.59034104
161Respiratory difficulties (HP:0002880)1.58997542
162Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.54422983
163Lipid accumulation in hepatocytes (HP:0006561)1.53816029
164Abnormality of the vocal cords (HP:0008777)1.53436031
165Abnormality of renal resorption (HP:0011038)1.53389234
166Exercise intolerance (HP:0003546)1.52879823

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK13.73786175
2WNK33.18709515
3MAPK133.13161933
4MAP4K22.98928465
5CASK2.81902274
6PINK12.70681997
7MAP3K122.58227813
8EPHA32.57308486
9SIK32.48776655
10MAP3K42.46016142
11NME12.42798465
12DYRK22.39103533
13SIK22.37217766
14MAP2K72.28800599
15EPHA42.28397406
16MINK12.19188175
17KSR12.18547193
18WNK42.09088116
19PNCK2.06823599
20GRK62.04108265
21TRIM282.00739003
22NTRK21.94964776
23BMPR1B1.79044480
24CDK191.77927524
25OXSR11.66135336
26TGFBR11.61232658
27TNIK1.57547379
28BCKDK1.56300461
29EPHB21.53270868
30CSNK1G31.46457156
31UHMK11.41868106
32PAK31.33531131
33CSNK1G21.31325986
34MAP3K91.28360981
35BUB11.27490907
36NTRK31.23676157
37LATS21.22616790
38DAPK21.20767648
39CCNB11.20040177
40PRKD31.18698813
41TIE11.18566269
42CSNK1G11.11865460
43CAMKK21.10321340
44GRK11.09705953
45STK161.09508907
46SRPK11.08377727
47PLK21.08266449
48DYRK1A1.04596115
49LIMK11.04481303
50MYLK1.04226467
51BCR1.04177931
52MKNK11.03551900
53CDK81.03518421
54DYRK1B1.03134845
55TSSK61.02995943
56DAPK11.02944630
57MKNK21.02596963
58PAK60.99149530
59CDC70.95594296
60ACVR1B0.94964863
61MARK20.94705498
62SYK0.94124922
63CAMKK10.91978595
64ADRBK20.91260141
65MAPK150.90525259
66MAP3K100.89925653
67SGK2230.87551415
68SGK4940.87551415
69PRKCI0.86074199
70MAP3K110.82010764
71MAP4K10.80833274
72PHKG20.78649051
73PHKG10.78649051
74PTK2B0.78393073
75CDK50.77877392
76VRK10.77574011
77ERBB30.76063509
78CAMK10.72689333
79PRKCE0.72285525
80GRK50.71733846
81CSNK1A1L0.71528053
82CAMK2B0.70745447
83NEK10.69725019
84FRK0.69598253
85INSRR0.68549287
86FGR0.68295260
87CAMK2A0.67371585
88CDK180.67100797
89GRK70.66379572
90ADRBK10.65922530
91CDK140.65437997
92TLK10.65037007
93PKN10.64559358
94RPS6KA20.64449115
95PLK30.62855166
96MAP2K40.60312709
97PRKACA0.59701276
98TAOK30.59205981
99CAMK40.56548860
100CDK150.56478146
101CSNK1A10.54267960
102CDK11A0.53698226
103PRKCG0.53215854
104WEE10.52891093
105STK110.52350655
106SGK20.50732343
107ARAF0.50390104
108NUAK10.49911408
109ILK0.49545878
110SCYL20.48866095
111TYRO30.48382695
112PDK40.47515374
113PDK30.47515374
114NLK0.45434016
115CSF1R0.44945349
116PIK3CA0.44033213
117DYRK30.43658190
118BRD40.42752511
119PRKCH0.41658579
120CSNK1E0.41323256
121PRKCZ0.40482185
122MAPK90.40265829
123NTRK10.39761510
124IRAK20.39714346
125ROCK20.39607132
126ERBB20.38274036
127PRKACB0.38072954
128MAP3K130.37201661
129PRKG10.37089784
130AKT20.36826201
131PRKAA10.35749676
132AURKA0.35654949
133CSNK1D0.33020218
134RIPK40.33002997
135BRAF0.32671779
136DAPK30.32601107
137SGK10.31666383
138TESK10.31398482
139STK390.29873958
140CAMK1G0.29273544

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001903.16267192
2Parkinsons disease_Homo sapiens_hsa050123.13465994
3Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.70473901
4Phototransduction_Homo sapiens_hsa047442.68410618
5Ribosome_Homo sapiens_hsa030102.56834431
6Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.48587297
7Collecting duct acid secretion_Homo sapiens_hsa049662.47403114
8Nicotine addiction_Homo sapiens_hsa050332.42546903
9Synaptic vesicle cycle_Homo sapiens_hsa047212.37320332
10Alzheimers disease_Homo sapiens_hsa050102.18645832
11Huntingtons disease_Homo sapiens_hsa050162.12990391
12Proteasome_Homo sapiens_hsa030502.10386126
13Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.08861168
14Dopaminergic synapse_Homo sapiens_hsa047281.84774823
15Amphetamine addiction_Homo sapiens_hsa050311.83261286
16Long-term potentiation_Homo sapiens_hsa047201.75731379
17Cardiac muscle contraction_Homo sapiens_hsa042601.74585497
18Vibrio cholerae infection_Homo sapiens_hsa051101.73630529
19Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.71551576
20Steroid biosynthesis_Homo sapiens_hsa001001.65116527
21Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.61165135
22Spliceosome_Homo sapiens_hsa030401.60709068
23Cocaine addiction_Homo sapiens_hsa050301.57975933
24Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.53910169
25Axon guidance_Homo sapiens_hsa043601.53525590
26Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.47116905
27Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.40703507
28Circadian entrainment_Homo sapiens_hsa047131.38287111
29Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.35365667
30Oocyte meiosis_Homo sapiens_hsa041141.33419294
31Serotonergic synapse_Homo sapiens_hsa047261.29213995
32Taste transduction_Homo sapiens_hsa047421.26141897
33Propanoate metabolism_Homo sapiens_hsa006401.25508582
34Primary immunodeficiency_Homo sapiens_hsa053401.21369496
35Olfactory transduction_Homo sapiens_hsa047401.19428280
36Mismatch repair_Homo sapiens_hsa034301.16211264
37Glutamatergic synapse_Homo sapiens_hsa047241.15767082
38Linoleic acid metabolism_Homo sapiens_hsa005911.14490803
39RNA polymerase_Homo sapiens_hsa030201.14427374
40Long-term depression_Homo sapiens_hsa047301.13942521
41Morphine addiction_Homo sapiens_hsa050321.13076826
42beta-Alanine metabolism_Homo sapiens_hsa004101.12843473
43Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.12542332
44Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.12325961
45Protein export_Homo sapiens_hsa030601.11640247
46Gap junction_Homo sapiens_hsa045401.11021504
47alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.10920886
48GABAergic synapse_Homo sapiens_hsa047271.08799086
49RNA degradation_Homo sapiens_hsa030181.07080088
50Gastric acid secretion_Homo sapiens_hsa049711.06506505
51Melanogenesis_Homo sapiens_hsa049161.04571347
52Hedgehog signaling pathway_Homo sapiens_hsa043401.04162318
53Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.00667092
54Renin secretion_Homo sapiens_hsa049241.00658914
55Basal cell carcinoma_Homo sapiens_hsa052170.99506249
56Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.98555357
57mRNA surveillance pathway_Homo sapiens_hsa030150.98029082
58Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.98019475
59Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.96872896
60Cholinergic synapse_Homo sapiens_hsa047250.95900611
61Wnt signaling pathway_Homo sapiens_hsa043100.90847759
62Insulin secretion_Homo sapiens_hsa049110.88787270
63Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.88401959
64Pyruvate metabolism_Homo sapiens_hsa006200.88395056
65Regulation of autophagy_Homo sapiens_hsa041400.86866408
66Nucleotide excision repair_Homo sapiens_hsa034200.86404022
67Ether lipid metabolism_Homo sapiens_hsa005650.85793463
68Base excision repair_Homo sapiens_hsa034100.83841711
69Cyanoamino acid metabolism_Homo sapiens_hsa004600.82489873
70B cell receptor signaling pathway_Homo sapiens_hsa046620.81274736
71Peroxisome_Homo sapiens_hsa041460.80983493
72Fanconi anemia pathway_Homo sapiens_hsa034600.80425535
73Alcoholism_Homo sapiens_hsa050340.78672906
74Oxytocin signaling pathway_Homo sapiens_hsa049210.78481743
75Aldosterone synthesis and secretion_Homo sapiens_hsa049250.78380566
76Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.78004824
77Pyrimidine metabolism_Homo sapiens_hsa002400.77654855
78DNA replication_Homo sapiens_hsa030300.77215009
79Colorectal cancer_Homo sapiens_hsa052100.75715292
80Calcium signaling pathway_Homo sapiens_hsa040200.75433225
81Hippo signaling pathway_Homo sapiens_hsa043900.74747909
82Arginine and proline metabolism_Homo sapiens_hsa003300.74023388
83Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.71494820
84Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.71290987
85Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.69693701
86Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.68804859
87Salivary secretion_Homo sapiens_hsa049700.68100875
88RNA transport_Homo sapiens_hsa030130.67432602
89GnRH signaling pathway_Homo sapiens_hsa049120.65609734
90Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.63877839
91Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.62834408
92Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.61779359
93Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.61206796
94Epstein-Barr virus infection_Homo sapiens_hsa051690.61097483
95Primary bile acid biosynthesis_Homo sapiens_hsa001200.60754706
96N-Glycan biosynthesis_Homo sapiens_hsa005100.59683989
97cGMP-PKG signaling pathway_Homo sapiens_hsa040220.59393941
98Tryptophan metabolism_Homo sapiens_hsa003800.58807678
99Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.58252075
100ErbB signaling pathway_Homo sapiens_hsa040120.57824102
101Endometrial cancer_Homo sapiens_hsa052130.57773246
102Basal transcription factors_Homo sapiens_hsa030220.57542799
103Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.56489938
104Cell cycle_Homo sapiens_hsa041100.55702677
105Glucagon signaling pathway_Homo sapiens_hsa049220.53740981
106MAPK signaling pathway_Homo sapiens_hsa040100.53117973
107Metabolic pathways_Homo sapiens_hsa011000.51982476
108Estrogen signaling pathway_Homo sapiens_hsa049150.49485960
109Thyroid cancer_Homo sapiens_hsa052160.48972720
110Fat digestion and absorption_Homo sapiens_hsa049750.47809314
111Sulfur relay system_Homo sapiens_hsa041220.47336518
112Caffeine metabolism_Homo sapiens_hsa002320.47030896
113cAMP signaling pathway_Homo sapiens_hsa040240.42837543
114Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.42830086
115Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.42784717
116Non-small cell lung cancer_Homo sapiens_hsa052230.42751919
1172-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.42609872
118Glioma_Homo sapiens_hsa052140.42547596
119Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.42351122
120Maturity onset diabetes of the young_Homo sapiens_hsa049500.42077802
121Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.41507148
122Selenocompound metabolism_Homo sapiens_hsa004500.41269585
123Neurotrophin signaling pathway_Homo sapiens_hsa047220.41248048
124Butanoate metabolism_Homo sapiens_hsa006500.40625846
125Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.37518793
126Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.37501201
127Ovarian steroidogenesis_Homo sapiens_hsa049130.37419470
128Chemical carcinogenesis_Homo sapiens_hsa052040.36607233
129Nitrogen metabolism_Homo sapiens_hsa009100.36205209
130Purine metabolism_Homo sapiens_hsa002300.34494041
131Pathways in cancer_Homo sapiens_hsa052000.34207304
132Phenylalanine metabolism_Homo sapiens_hsa003600.33809011
133Ras signaling pathway_Homo sapiens_hsa040140.33720549
134Thyroid hormone synthesis_Homo sapiens_hsa049180.33597151
135Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.30784711
136VEGF signaling pathway_Homo sapiens_hsa043700.30370442
137Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.27679401
138Non-homologous end-joining_Homo sapiens_hsa034500.27509344

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