Rank | Gene Set | Z-score |
---|---|---|
1 | ribosomal small subunit assembly (GO:0000028) | 5.20944914 |
2 | neutrophil activation involved in immune response (GO:0002283) | 5.09267113 |
3 | response to peptidoglycan (GO:0032494) | 5.08708145 |
4 | negative regulation of interleukin-12 production (GO:0032695) | 4.77292349 |
5 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 4.55913131 |
6 | modulation by symbiont of host immune response (GO:0052553) | 4.55913131 |
7 | positive regulation by symbiont of host defense response (GO:0052509) | 4.55913131 |
8 | modulation by symbiont of host defense response (GO:0052031) | 4.55913131 |
9 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 4.55913131 |
10 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 4.55913131 |
11 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.48399992 |
12 | telomere maintenance via semi-conservative replication (GO:0032201) | 4.46890742 |
13 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.30922887 |
14 | DNA strand elongation (GO:0022616) | 4.27252260 |
15 | viral transcription (GO:0019083) | 4.20285968 |
16 | DNA deamination (GO:0045006) | 4.15921713 |
17 | translational termination (GO:0006415) | 4.07564107 |
18 | formation of translation preinitiation complex (GO:0001731) | 4.05871702 |
19 | macrophage activation involved in immune response (GO:0002281) | 3.96487504 |
20 | maturation of SSU-rRNA (GO:0030490) | 3.95668532 |
21 | telomere maintenance via recombination (GO:0000722) | 3.91627836 |
22 | ribosomal small subunit biogenesis (GO:0042274) | 3.87831612 |
23 | DNA replication initiation (GO:0006270) | 3.87442254 |
24 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.79252273 |
25 | translational elongation (GO:0006414) | 3.74468918 |
26 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.72100340 |
27 | negative regulation of cell killing (GO:0031342) | 3.72100340 |
28 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 3.65367666 |
29 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.62545447 |
30 | DNA unwinding involved in DNA replication (GO:0006268) | 3.62192910 |
31 | positive regulation of mast cell activation (GO:0033005) | 3.61166646 |
32 | ribosomal large subunit biogenesis (GO:0042273) | 3.58025235 |
33 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.55687771 |
34 | mitotic recombination (GO:0006312) | 3.54262304 |
35 | regulation of mast cell degranulation (GO:0043304) | 3.52809873 |
36 | translational initiation (GO:0006413) | 3.51253014 |
37 | detection of other organism (GO:0098543) | 3.51195201 |
38 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.51091053 |
39 | nucleobase biosynthetic process (GO:0046112) | 3.50641764 |
40 | neutrophil activation (GO:0042119) | 3.48687405 |
41 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.47894585 |
42 | granulocyte activation (GO:0036230) | 3.46132914 |
43 | cotranslational protein targeting to membrane (GO:0006613) | 3.45976486 |
44 | negative regulation of myeloid cell apoptotic process (GO:0033033) | 3.45539678 |
45 | myeloid cell activation involved in immune response (GO:0002275) | 3.44925320 |
46 | telomere maintenance via telomere lengthening (GO:0010833) | 3.44744847 |
47 | protein targeting to ER (GO:0045047) | 3.43887760 |
48 | positive regulation of mast cell degranulation (GO:0043306) | 3.42251523 |
49 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 3.42251523 |
50 | DNA replication checkpoint (GO:0000076) | 3.40089240 |
51 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.39323903 |
52 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.36273799 |
53 | leukocyte aggregation (GO:0070486) | 3.35412649 |
54 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 3.35374056 |
55 | detection of bacterium (GO:0016045) | 3.35313870 |
56 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.34641638 |
57 | purine nucleobase biosynthetic process (GO:0009113) | 3.31660143 |
58 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.30007925 |
59 | response to host immune response (GO:0052572) | 3.28973880 |
60 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.28973880 |
61 | protein localization to endoplasmic reticulum (GO:0070972) | 3.25686606 |
62 | cellular extravasation (GO:0045123) | 3.24339533 |
63 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.23862001 |
64 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.22704912 |
65 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.22704912 |
66 | viral life cycle (GO:0019058) | 3.21825642 |
67 | IMP biosynthetic process (GO:0006188) | 3.21119634 |
68 | regulation of mast cell activation involved in immune response (GO:0033006) | 3.21026728 |
69 | detection of molecule of bacterial origin (GO:0032490) | 3.19765841 |
70 | cellular protein complex disassembly (GO:0043624) | 3.18874678 |
71 | regulation of mast cell activation (GO:0033003) | 3.18542233 |
72 | microglial cell activation (GO:0001774) | 3.18390518 |
73 | regulation of interferon-alpha production (GO:0032647) | 3.17440743 |
74 | positive regulation of B cell differentiation (GO:0045579) | 3.16833503 |
75 | ribosome biogenesis (GO:0042254) | 3.13289769 |
76 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.12709572 |
77 | detection of external biotic stimulus (GO:0098581) | 3.12073165 |
78 | positive regulation of interferon-alpha production (GO:0032727) | 3.12057423 |
79 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.10842621 |
80 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.10158700 |
81 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.10158700 |
82 | positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:0061081 | 3.08125059 |
83 | cellular response to type I interferon (GO:0071357) | 3.07302434 |
84 | type I interferon signaling pathway (GO:0060337) | 3.07302434 |
85 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.02273947 |
86 | T-helper 1 type immune response (GO:0042088) | 3.00571647 |
87 | response to type I interferon (GO:0034340) | 2.99773462 |
88 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 2.97662546 |
89 | regulation of antigen processing and presentation (GO:0002577) | 2.96423730 |
90 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.94844633 |
91 | rRNA processing (GO:0006364) | 2.94355193 |
92 | IMP metabolic process (GO:0046040) | 2.94091667 |
93 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 2.93492141 |
94 | NIK/NF-kappaB signaling (GO:0038061) | 2.91660986 |
95 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.91629908 |
96 | macrophage activation (GO:0042116) | 2.90478106 |
97 | response to muramyl dipeptide (GO:0032495) | 2.90192330 |
98 | pseudouridine synthesis (GO:0001522) | 2.90059092 |
99 | defense response to protozoan (GO:0042832) | 2.88836616 |
100 | negative regulation of cytokine production involved in immune response (GO:0002719) | 2.88788802 |
101 | response to host (GO:0075136) | 2.87844400 |
102 | response to host defenses (GO:0052200) | 2.87844400 |
103 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 2.87844400 |
104 | leukocyte degranulation (GO:0043299) | 2.87201295 |
105 | protein localization to kinetochore (GO:0034501) | 2.86255645 |
106 | positive regulation of antigen processing and presentation (GO:0002579) | 2.86174323 |
107 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 2.86076316 |
108 | response to interferon-beta (GO:0035456) | 2.85398647 |
109 | response to protozoan (GO:0001562) | 2.84745263 |
110 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.83614753 |
111 | rRNA metabolic process (GO:0016072) | 2.83585753 |
112 | mitotic nuclear envelope disassembly (GO:0007077) | 2.83382506 |
113 | protein complex disassembly (GO:0043241) | 2.80979812 |
114 | proteasome assembly (GO:0043248) | 2.80592338 |
115 | regulation of leukocyte degranulation (GO:0043300) | 2.80424163 |
116 | cellular response to interferon-gamma (GO:0071346) | 2.80293815 |
117 | CENP-A containing nucleosome assembly (GO:0034080) | 2.80153088 |
118 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.79443369 |
119 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 2.79337666 |
120 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.79117361 |
121 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 2.78822852 |
122 | ribosome assembly (GO:0042255) | 2.78160475 |
123 | translation (GO:0006412) | 2.77296303 |
124 | folic acid metabolic process (GO:0046655) | 2.76899850 |
125 | regulation of B cell apoptotic process (GO:0002902) | 2.76729469 |
126 | purine nucleotide salvage (GO:0032261) | 2.75896241 |
127 | regulation of B cell receptor signaling pathway (GO:0050855) | 2.75419863 |
128 | mature B cell differentiation involved in immune response (GO:0002313) | 2.74971854 |
129 | regulation of interleukin-12 production (GO:0032655) | 2.74746066 |
130 | detection of biotic stimulus (GO:0009595) | 2.74494524 |
131 | positive regulation of interferon-beta production (GO:0032728) | 2.74462235 |
132 | myeloid dendritic cell activation (GO:0001773) | 2.74293030 |
133 | regulation of gamma-delta T cell activation (GO:0046643) | 2.73528878 |
134 | chromatin remodeling at centromere (GO:0031055) | 2.73485011 |
135 | negative regulation of inflammatory response to antigenic stimulus (GO:0002862) | 2.72464924 |
136 | negative regulation of phagocytosis (GO:0050765) | 2.72157467 |
137 | B cell mediated immunity (GO:0019724) | 2.72120875 |
138 | immunoglobulin mediated immune response (GO:0016064) | 2.70809211 |
139 | response to interferon-gamma (GO:0034341) | 2.68831987 |
140 | transcription-coupled nucleotide-excision repair (GO:0006283) | 2.68812685 |
141 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.66789363 |
142 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.66789363 |
143 | macromolecular complex disassembly (GO:0032984) | 2.66519606 |
144 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.63577047 |
145 | regulation of protein heterodimerization activity (GO:0043497) | 2.63503216 |
146 | telomere maintenance (GO:0000723) | 2.63434467 |
147 | positive regulation of interleukin-17 production (GO:0032740) | 2.63195505 |
148 | telomere organization (GO:0032200) | 2.63121500 |
149 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.62901677 |
150 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 2.62102757 |
151 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.61480130 |
152 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 2.61263132 |
153 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 2.61044869 |
154 | G1/S transition of mitotic cell cycle (GO:0000082) | 2.60756550 |
155 | cell cycle G1/S phase transition (GO:0044843) | 2.60756550 |
156 | spliceosomal snRNP assembly (GO:0000387) | 2.60645824 |
157 | myeloid leukocyte activation (GO:0002274) | 2.60213549 |
158 | positive regulation of interleukin-10 production (GO:0032733) | 2.59799402 |
159 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 2.59424401 |
160 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.59288246 |
161 | membrane disassembly (GO:0030397) | 2.59047015 |
162 | nuclear envelope disassembly (GO:0051081) | 2.59047015 |
163 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.58657995 |
164 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.58178964 |
165 | isotype switching (GO:0045190) | 2.58178964 |
166 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.58178964 |
167 | neutrophil mediated immunity (GO:0002446) | 2.57604479 |
168 | purine deoxyribonucleotide catabolic process (GO:0009155) | 2.57468825 |
169 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 2.56271737 |
170 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.55749822 |
171 | negative regulation of ligase activity (GO:0051352) | 2.55749822 |
172 | regulation of interleukin-17 production (GO:0032660) | 2.55506755 |
173 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.55201889 |
174 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.55201889 |
175 | regulation of alpha-beta T cell proliferation (GO:0046640) | 2.55156479 |
176 | positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557) | 2.54469242 |
177 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.53941099 |
178 | DNA replication-independent nucleosome organization (GO:0034724) | 2.53941099 |
179 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.52159440 |
180 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.52159440 |
181 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.52159440 |
182 | cellular component biogenesis (GO:0044085) | 2.52154087 |
183 | mRNA catabolic process (GO:0006402) | 2.49973669 |
184 | RNA catabolic process (GO:0006401) | 2.49100702 |
185 | protein localization to chromosome, centromeric region (GO:0071459) | 2.48648701 |
186 | base-excision repair (GO:0006284) | 2.46991786 |
187 | respiratory burst (GO:0045730) | 2.46709308 |
188 | pentose-phosphate shunt (GO:0006098) | 2.46252252 |
189 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.46041711 |
190 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.46041711 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 7.20788999 |
2 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.81339697 |
3 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.75593036 |
4 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.82052802 |
5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.73388524 |
6 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.70374609 |
7 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.63429974 |
8 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.61810353 |
9 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.58342110 |
10 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.55059408 |
11 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.50941345 |
12 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.43679223 |
13 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.41915510 |
14 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.40833836 |
15 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.34281967 |
16 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.32445765 |
17 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.31925194 |
18 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.29584061 |
19 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.18744109 |
20 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.18221840 |
21 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.16993177 |
22 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.13577380 |
23 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.13540389 |
24 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.09913660 |
25 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.07817525 |
26 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.07704406 |
27 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.04047641 |
28 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.02769234 |
29 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 2.02111165 |
30 | * MYC_22102868_ChIP-Seq_BL_Human | 1.99912548 |
31 | * NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.98721576 |
32 | * SPI1_23127762_ChIP-Seq_K562_Human | 1.96654766 |
33 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.96389909 |
34 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.95247909 |
35 | * IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.94992076 |
36 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.91372057 |
37 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.83490783 |
38 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.83143983 |
39 | * MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.83101380 |
40 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.82338953 |
41 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.76425654 |
42 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.73400883 |
43 | * SPI1_23547873_ChIP-Seq_NB4_Human | 1.73214878 |
44 | * HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.71855676 |
45 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.71810592 |
46 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.69809861 |
47 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.68946664 |
48 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.67619514 |
49 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.66301218 |
50 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.65537049 |
51 | * MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.64854673 |
52 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.58852167 |
53 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.57213741 |
54 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.56210971 |
55 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.54471472 |
56 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.52966095 |
57 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.52526525 |
58 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.51681917 |
59 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.49610178 |
60 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.48771066 |
61 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.47973799 |
62 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.47249958 |
63 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.46563217 |
64 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.46417929 |
65 | * RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.45012433 |
66 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.44212721 |
67 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.43871769 |
68 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.43166145 |
69 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.42939204 |
70 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.42197061 |
71 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.40350496 |
72 | MAF_26560356_Chip-Seq_TH2_Human | 1.38736658 |
73 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.37880721 |
74 | * BCL6_27268052_Chip-Seq_Bcells_Human | 1.35056331 |
75 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.34627883 |
76 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.34325916 |
77 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.34116438 |
78 | * ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.33434674 |
79 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.33332057 |
80 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.32005571 |
81 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.31931065 |
82 | * PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.29794999 |
83 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.29716508 |
84 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.29558531 |
85 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.28877063 |
86 | * PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.26229711 |
87 | * CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.25744999 |
88 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.25350977 |
89 | * CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.22573752 |
90 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.22534748 |
91 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.21065776 |
92 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.21010208 |
93 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.20806501 |
94 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.20406831 |
95 | * PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.19857292 |
96 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.19493035 |
97 | GATA1_22025678_ChIP-Seq_K562_Human | 1.18032005 |
98 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.17731300 |
99 | * RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.17710398 |
100 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.16648100 |
101 | * BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.15832291 |
102 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.15044598 |
103 | * GATA3_26560356_Chip-Seq_TH2_Human | 1.14201906 |
104 | * MYB_26560356_Chip-Seq_TH2_Human | 1.13245193 |
105 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.12643514 |
106 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.12600115 |
107 | * BCOR_27268052_Chip-Seq_Bcells_Human | 1.11856091 |
108 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.11207088 |
109 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.10709750 |
110 | MYB_26560356_Chip-Seq_TH1_Human | 1.09733308 |
111 | * NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.09248574 |
112 | * MAF_26560356_Chip-Seq_TH1_Human | 1.08368893 |
113 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.06738593 |
114 | * GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.06728786 |
115 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.05480752 |
116 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.04946686 |
117 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.03892590 |
118 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.03664796 |
119 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.03613087 |
120 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.03601438 |
121 | * IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.02930165 |
122 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.02043955 |
123 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.01855966 |
124 | * FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.01484265 |
125 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.01255991 |
126 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.01123470 |
127 | * UTX_26944678_Chip-Seq_JUKART_Human | 1.01010902 |
128 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.01006430 |
129 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.99851189 |
130 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.99849733 |
131 | * GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.98992925 |
132 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 0.98551013 |
133 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.98422816 |
134 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.97201448 |
135 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.96150370 |
136 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.94586788 |
137 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.92479740 |
138 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 0.91896103 |
139 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.91847806 |
140 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 0.89695072 |
141 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.89473116 |
142 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.87652304 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 3.92424606 |
2 | MP0010094_abnormal_chromosome_stability | 3.34491063 |
3 | MP0001835_abnormal_antigen_presentation | 3.34052424 |
4 | MP0002396_abnormal_hematopoietic_system | 3.29763347 |
5 | MP0004957_abnormal_blastocyst_morpholog | 3.00527937 |
6 | MP0003111_abnormal_nucleus_morphology | 2.85276124 |
7 | MP0003077_abnormal_cell_cycle | 2.80994992 |
8 | MP0008057_abnormal_DNA_replication | 2.57801159 |
9 | MP0009785_altered_susceptibility_to | 2.49294151 |
10 | MP0003436_decreased_susceptibility_to | 2.42783471 |
11 | MP0001800_abnormal_humoral_immune | 2.33740463 |
12 | MP0008058_abnormal_DNA_repair | 2.32082962 |
13 | MP0000685_abnormal_immune_system | 2.28842695 |
14 | * MP0009764_decreased_sensitivity_to | 2.25051562 |
15 | MP0005671_abnormal_response_to | 2.21220848 |
16 | MP0002398_abnormal_bone_marrow | 2.14026593 |
17 | MP0009333_abnormal_splenocyte_physiolog | 2.12987893 |
18 | MP0002452_abnormal_antigen_presenting | 2.12902684 |
19 | MP0000490_abnormal_crypts_of | 2.10449306 |
20 | MP0005025_abnormal_response_to | 2.06093376 |
21 | MP0008007_abnormal_cellular_replicative | 2.04962891 |
22 | MP0005000_abnormal_immune_tolerance | 2.04259370 |
23 | MP0003075_altered_response_to | 2.03170815 |
24 | MP0001545_abnormal_hematopoietic_system | 2.02619132 |
25 | MP0005397_hematopoietic_system_phenotyp | 2.02619132 |
26 | MP0000689_abnormal_spleen_morphology | 2.01356404 |
27 | MP0002420_abnormal_adaptive_immunity | 2.00096998 |
28 | MP0001819_abnormal_immune_cell | 1.98111812 |
29 | MP0002723_abnormal_immune_serum | 1.95832175 |
30 | MP0001853_heart_inflammation | 1.94851913 |
31 | MP0001790_abnormal_immune_system | 1.91709221 |
32 | MP0005387_immune_system_phenotype | 1.91709221 |
33 | MP0002419_abnormal_innate_immunity | 1.90086640 |
34 | MP0002148_abnormal_hypersensitivity_rea | 1.89488117 |
35 | MP0004808_abnormal_hematopoietic_stem | 1.88456965 |
36 | MP0003763_abnormal_thymus_physiology | 1.86952714 |
37 | MP0002722_abnormal_immune_system | 1.86775493 |
38 | MP0000716_abnormal_immune_system | 1.83198752 |
39 | MP0004510_myositis | 1.82405517 |
40 | MP0003300_gastrointestinal_ulcer | 1.76020165 |
41 | MP0010307_abnormal_tumor_latency | 1.75967712 |
42 | MP0002429_abnormal_blood_cell | 1.73581745 |
43 | MP0005464_abnormal_platelet_physiology | 1.72895179 |
44 | MP0003303_peritoneal_inflammation | 1.69878603 |
45 | MP0003806_abnormal_nucleotide_metabolis | 1.66477359 |
46 | MP0008260_abnormal_autophagy | 1.61684247 |
47 | MP0002019_abnormal_tumor_incidence | 1.60148675 |
48 | MP0002166_altered_tumor_susceptibility | 1.59707975 |
49 | MP0002405_respiratory_system_inflammati | 1.59538321 |
50 | MP0000858_altered_metastatic_potential | 1.59393509 |
51 | MP0010352_gastrointestinal_tract_polyps | 1.58911281 |
52 | MP0005174_abnormal_tail_pigmentation | 1.54126669 |
53 | MP0003186_abnormal_redox_activity | 1.49130956 |
54 | MP0005451_abnormal_body_composition | 1.45875987 |
55 | MP0000350_abnormal_cell_proliferation | 1.42847581 |
56 | MP0010155_abnormal_intestine_physiology | 1.42628983 |
57 | MP0000703_abnormal_thymus_morphology | 1.41462839 |
58 | MP0003172_abnormal_lysosome_physiology | 1.41460086 |
59 | * MP0001845_abnormal_inflammatory_respons | 1.40108683 |
60 | MP0008932_abnormal_embryonic_tissue | 1.39375665 |
61 | MP0006082_CNS_inflammation | 1.32583422 |
62 | MP0000465_gastrointestinal_hemorrhage | 1.31672174 |
63 | MP0002006_tumorigenesis | 1.30001970 |
64 | MP0005075_abnormal_melanosome_morpholog | 1.29852088 |
65 | MP0003724_increased_susceptibility_to | 1.29580656 |
66 | MP0003786_premature_aging | 1.26105473 |
67 | MP0003656_abnormal_erythrocyte_physiolo | 1.26052314 |
68 | * MP0000313_abnormal_cell_death | 1.25989003 |
69 | MP0001730_embryonic_growth_arrest | 1.25922046 |
70 | MP0009278_abnormal_bone_marrow | 1.17742631 |
71 | MP0005058_abnormal_lysosome_morphology | 1.17725879 |
72 | * MP0005166_decreased_susceptibility_to | 1.17248235 |
73 | MP0008469_abnormal_protein_level | 1.16544705 |
74 | MP0000604_amyloidosis | 1.15985232 |
75 | MP0005310_abnormal_salivary_gland | 1.15058134 |
76 | MP0006054_spinal_hemorrhage | 1.14854778 |
77 | MP0000343_altered_response_to | 1.10791085 |
78 | MP0005167_abnormal_blood-brain_barrier | 1.09744007 |
79 | MP0002998_abnormal_bone_remodeling | 1.09342575 |
80 | MP0002139_abnormal_hepatobiliary_system | 1.07568138 |
81 | MP0009379_abnormal_foot_pigmentation | 1.06217765 |
82 | MP0001873_stomach_inflammation | 1.02955590 |
83 | MP0002277_abnormal_respiratory_mucosa | 0.97642071 |
84 | MP0001533_abnormal_skeleton_physiology | 0.97313428 |
85 | MP0009840_abnormal_foam_cell | 0.95596830 |
86 | MP0003448_altered_tumor_morphology | 0.94756221 |
87 | MP0000358_abnormal_cell_content/ | 0.94015450 |
88 | MP0003866_abnormal_defecation | 0.93398229 |
89 | MP0004947_skin_inflammation | 0.91731014 |
90 | MP0000015_abnormal_ear_pigmentation | 0.91195956 |
91 | MP0009765_abnormal_xenobiotic_induced | 0.90518747 |
92 | MP0005023_abnormal_wound_healing | 0.90117390 |
93 | MP0001663_abnormal_digestive_system | 0.89922526 |
94 | MP0002132_abnormal_respiratory_system | 0.89362398 |
95 | * MP0002080_prenatal_lethality | 0.86944365 |
96 | MP0002095_abnormal_skin_pigmentation | 0.83717217 |
97 | MP0001764_abnormal_homeostasis | 0.83281979 |
98 | MP0002138_abnormal_hepatobiliary_system | 0.82372862 |
99 | MP0002332_abnormal_exercise_endurance | 0.81671607 |
100 | MP0003183_abnormal_peptide_metabolism | 0.80810975 |
101 | MP0005164_abnormal_response_to | 0.80268561 |
102 | MP0003690_abnormal_glial_cell | 0.78540326 |
103 | MP0003221_abnormal_cardiomyocyte_apopto | 0.78121019 |
104 | MP0001697_abnormal_embryo_size | 0.77911689 |
105 | MP0003828_pulmonary_edema | 0.77682772 |
106 | MP0005319_abnormal_enzyme/_coenzyme | 0.76948136 |
107 | MP0005165_increased_susceptibility_to | 0.76878324 |
108 | MP0005390_skeleton_phenotype | 0.76651102 |
109 | * MP0006036_abnormal_mitochondrial_physio | 0.76124407 |
110 | MP0003191_abnormal_cellular_cholesterol | 0.75424673 |
111 | MP0004147_increased_porphyrin_level | 0.75175327 |
112 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.75129218 |
113 | MP0009763_increased_sensitivity_to | 0.75100055 |
114 | MP0008874_decreased_physiological_sensi | 0.74971635 |
115 | MP0002254_reproductive_system_inflammat | 0.74927408 |
116 | MP0000477_abnormal_intestine_morphology | 0.71543593 |
117 | MP0008873_increased_physiological_sensi | 0.71379567 |
118 | MP0004883_abnormal_blood_vessel | 0.70796756 |
119 | MP0006035_abnormal_mitochondrial_morpho | 0.70112140 |
120 | * MP0000598_abnormal_liver_morphology | 0.69428383 |
121 | MP0008004_abnormal_stomach_pH | 0.69035544 |
122 | MP0005621_abnormal_cell_physiology | 0.67426819 |
123 | MP0003718_maternal_effect | 0.66044862 |
124 | MP0000371_diluted_coat_color | 0.65940471 |
125 | MP0001542_abnormal_bone_strength | 0.65929867 |
126 | MP0001851_eye_inflammation | 0.65347437 |
127 | MP0005384_cellular_phenotype | 0.65286449 |
128 | MP0001727_abnormal_embryo_implantation | 0.63589463 |
129 | MP0001672_abnormal_embryogenesis/_devel | 0.61817090 |
130 | MP0005380_embryogenesis_phenotype | 0.61817090 |
131 | MP0002877_abnormal_melanocyte_morpholog | 0.61547675 |
132 | MP0002933_joint_inflammation | 0.61345164 |
133 | MP0003795_abnormal_bone_structure | 0.60996197 |
134 | MP0002136_abnormal_kidney_physiology | 0.60872633 |
135 | MP0003453_abnormal_keratinocyte_physiol | 0.60534749 |
136 | MP0000249_abnormal_blood_vessel | 0.58992343 |
137 | MP0000609_abnormal_liver_physiology | 0.57519745 |
138 | MP0003195_calcinosis | 0.56206410 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormality of liposaccharide metabolism (HP:0010968) | 4.53086373 |
2 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 4.53086373 |
3 | Abnormality of glycolipid metabolism (HP:0010969) | 4.53086373 |
4 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.48119740 |
5 | Abnormal number of erythroid precursors (HP:0012131) | 4.31473808 |
6 | Reticulocytopenia (HP:0001896) | 4.30409300 |
7 | Stomatitis (HP:0010280) | 4.30222534 |
8 | Recurrent abscess formation (HP:0002722) | 4.12310858 |
9 | Orchitis (HP:0100796) | 4.03713381 |
10 | Thrombocytosis (HP:0001894) | 3.95631741 |
11 | Optic neuritis (HP:0100653) | 3.91188726 |
12 | Retrobulbar optic neuritis (HP:0100654) | 3.91188726 |
13 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.62321175 |
14 | IgM deficiency (HP:0002850) | 3.60057565 |
15 | Recurrent bacterial skin infections (HP:0005406) | 3.57654651 |
16 | Increased IgM level (HP:0003496) | 3.48789365 |
17 | Aplastic anemia (HP:0001915) | 3.34576596 |
18 | Increased cerebral lipofuscin (HP:0011813) | 3.19863814 |
19 | Eczematoid dermatitis (HP:0000976) | 3.10397213 |
20 | Urticaria (HP:0001025) | 3.06957816 |
21 | Agnosia (HP:0010524) | 3.06247730 |
22 | Petechiae (HP:0000967) | 3.04900426 |
23 | Oral leukoplakia (HP:0002745) | 3.01821622 |
24 | Birth length less than 3rd percentile (HP:0003561) | 3.01028087 |
25 | Pallor (HP:0000980) | 2.97802727 |
26 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.92623396 |
27 | Recurrent cutaneous fungal infections (HP:0011370) | 2.92623396 |
28 | Myositis (HP:0100614) | 2.87964402 |
29 | Macrocytic anemia (HP:0001972) | 2.85808353 |
30 | Recurrent bronchitis (HP:0002837) | 2.85048910 |
31 | Purpura (HP:0000979) | 2.80490838 |
32 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.78937759 |
33 | Degeneration of anterior horn cells (HP:0002398) | 2.78820053 |
34 | Abnormality of the anterior horn cell (HP:0006802) | 2.78820053 |
35 | Loss of speech (HP:0002371) | 2.73404140 |
36 | Amyloidosis (HP:0011034) | 2.72766649 |
37 | Chronic otitis media (HP:0000389) | 2.69762150 |
38 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.68646880 |
39 | Obstructive lung disease (HP:0006536) | 2.67559629 |
40 | Chronic obstructive pulmonary disease (HP:0006510) | 2.67559629 |
41 | Dysostosis multiplex (HP:0000943) | 2.66014128 |
42 | Pulmonary infiltrates (HP:0002113) | 2.65193654 |
43 | Lymphoma (HP:0002665) | 2.63595943 |
44 | Cellulitis (HP:0100658) | 2.63516164 |
45 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.62413018 |
46 | Keratoconjunctivitis sicca (HP:0001097) | 2.61806833 |
47 | Recurrent viral infections (HP:0004429) | 2.59352736 |
48 | Mediastinal lymphadenopathy (HP:0100721) | 2.56457442 |
49 | Poikiloderma (HP:0001029) | 2.55622954 |
50 | Systemic lupus erythematosus (HP:0002725) | 2.55160942 |
51 | Reduced antithrombin III activity (HP:0001976) | 2.51619202 |
52 | Hepatosplenomegaly (HP:0001433) | 2.50798585 |
53 | Disinhibition (HP:0000734) | 2.50742777 |
54 | Hemoptysis (HP:0002105) | 2.50556328 |
55 | Abnormality of macrophages (HP:0004311) | 2.50267770 |
56 | Meningitis (HP:0001287) | 2.48441311 |
57 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.47013190 |
58 | Keratoconjunctivitis (HP:0001096) | 2.45925427 |
59 | Pustule (HP:0200039) | 2.45867494 |
60 | Rough bone trabeculation (HP:0100670) | 2.44430933 |
61 | 11 pairs of ribs (HP:0000878) | 2.44280810 |
62 | Abnormality of T cell physiology (HP:0011840) | 2.43761672 |
63 | IgG deficiency (HP:0004315) | 2.43229468 |
64 | Mutism (HP:0002300) | 2.43113456 |
65 | Myelodysplasia (HP:0002863) | 2.40959637 |
66 | Anorexia (HP:0002039) | 2.40070728 |
67 | Type I transferrin isoform profile (HP:0003642) | 2.40003456 |
68 | Gastrointestinal infarctions (HP:0005244) | 2.38816830 |
69 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.38677635 |
70 | Recurrent fungal infections (HP:0002841) | 2.38492954 |
71 | Hypergammaglobulinemia (HP:0010702) | 2.36340544 |
72 | Lymphopenia (HP:0001888) | 2.34792008 |
73 | Autoimmune thrombocytopenia (HP:0001973) | 2.34655407 |
74 | Spontaneous hematomas (HP:0007420) | 2.34100466 |
75 | Multiple enchondromatosis (HP:0005701) | 2.32046873 |
76 | Hypertensive crisis (HP:0100735) | 2.29344888 |
77 | Autoimmune hemolytic anemia (HP:0001890) | 2.29160516 |
78 | Chromsome breakage (HP:0040012) | 2.28105974 |
79 | Poor head control (HP:0002421) | 2.26507421 |
80 | Abnormality of T cells (HP:0002843) | 2.24224261 |
81 | Progressive neurologic deterioration (HP:0002344) | 2.24044354 |
82 | Increased IgE level (HP:0003212) | 2.23694272 |
83 | Recurrent skin infections (HP:0001581) | 2.22526970 |
84 | Gingivitis (HP:0000230) | 2.22170589 |
85 | Bone marrow hypocellularity (HP:0005528) | 2.22149357 |
86 | Leukocytosis (HP:0001974) | 2.21742342 |
87 | Microretrognathia (HP:0000308) | 2.20426588 |
88 | Abnormality of B cell number (HP:0010975) | 2.20158898 |
89 | B lymphocytopenia (HP:0010976) | 2.20158898 |
90 | Abnormality of pyrimidine metabolism (HP:0004353) | 2.19529509 |
91 | Squamous cell carcinoma (HP:0002860) | 2.17630490 |
92 | Gangrene (HP:0100758) | 2.17528120 |
93 | Gingival bleeding (HP:0000225) | 2.16513753 |
94 | Abnormality of T cell number (HP:0011839) | 2.15788753 |
95 | Arterial thrombosis (HP:0004420) | 2.15067618 |
96 | Chest pain (HP:0100749) | 2.15054764 |
97 | Agammaglobulinemia (HP:0004432) | 2.14967564 |
98 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.14837543 |
99 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.14837543 |
100 | Pancytopenia (HP:0001876) | 2.14575754 |
101 | Polyneuropathy (HP:0001271) | 2.14224587 |
102 | Absent thumb (HP:0009777) | 2.13839130 |
103 | IgA deficiency (HP:0002720) | 2.13455204 |
104 | Vacuolated lymphocytes (HP:0001922) | 2.13180688 |
105 | Abnormality of iron homeostasis (HP:0011031) | 2.12466637 |
106 | Abnormality of chromosome stability (HP:0003220) | 2.11437229 |
107 | Abnormality of the preputium (HP:0100587) | 2.10472278 |
108 | T lymphocytopenia (HP:0005403) | 2.10123615 |
109 | Basal cell carcinoma (HP:0002671) | 2.09240106 |
110 | Colon cancer (HP:0003003) | 2.08458433 |
111 | Episodic fever (HP:0001954) | 2.08183302 |
112 | Vasculitis (HP:0002633) | 2.06765240 |
113 | Osteomyelitis (HP:0002754) | 2.06539632 |
114 | Premature graying of hair (HP:0002216) | 2.05285710 |
115 | Nasal polyposis (HP:0100582) | 2.03205294 |
116 | Leukopenia (HP:0001882) | 2.01273338 |
117 | Gastrointestinal stroma tumor (HP:0100723) | 2.01042551 |
118 | Pulmonary fibrosis (HP:0002206) | 2.00822955 |
119 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 2.00473009 |
120 | Abnormality of the prostate (HP:0008775) | 2.00313253 |
121 | Abnormality of the pleura (HP:0002103) | 2.00239500 |
122 | Skin rash (HP:0000988) | 2.00239278 |
123 | Panhypogammaglobulinemia (HP:0003139) | 2.00178229 |
124 | Eosinophilia (HP:0001880) | 1.99577262 |
125 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.99177767 |
126 | Abnormality of polysaccharide metabolism (HP:0011012) | 1.98714921 |
127 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 1.98714921 |
128 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 1.98714921 |
129 | Selective tooth agenesis (HP:0001592) | 1.96048465 |
130 | Recurrent lower respiratory tract infections (HP:0002783) | 1.94895645 |
131 | Glomerulopathy (HP:0100820) | 1.94594006 |
132 | Hepatocellular necrosis (HP:0001404) | 1.93424327 |
133 | Pulmonary embolism (HP:0002204) | 1.92810379 |
134 | Amaurosis fugax (HP:0100576) | 1.91554584 |
135 | Entropion (HP:0000621) | 1.91465734 |
136 | Granulocytopenia (HP:0001913) | 1.91102689 |
137 | Inflammation of the large intestine (HP:0002037) | 1.90298547 |
138 | Recurrent pneumonia (HP:0006532) | 1.90180047 |
139 | Trismus (HP:0000211) | 1.89872208 |
140 | Cutaneous melanoma (HP:0012056) | 1.89286245 |
141 | Breast hypoplasia (HP:0003187) | 1.89071993 |
142 | Sepsis (HP:0100806) | 1.88628672 |
143 | Abnormality of reticulocytes (HP:0004312) | 1.88191971 |
144 | Nausea (HP:0002018) | 1.88078834 |
145 | Skin ulcer (HP:0200042) | 1.86389338 |
146 | Encephalitis (HP:0002383) | 1.85798438 |
147 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.85418221 |
148 | Abnormal protein glycosylation (HP:0012346) | 1.85309225 |
149 | Abnormal glycosylation (HP:0012345) | 1.85309225 |
150 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.85309225 |
151 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.85309225 |
152 | Personality changes (HP:0000751) | 1.84968062 |
153 | Prolonged bleeding time (HP:0003010) | 1.83974079 |
154 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.83629302 |
155 | Increased serum ferritin (HP:0003281) | 1.83164032 |
156 | Mitochondrial inheritance (HP:0001427) | 1.82712590 |
157 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.82551060 |
158 | Gastrointestinal inflammation (HP:0004386) | 1.82435018 |
159 | Abnormal trabecular bone morphology (HP:0100671) | 1.81816320 |
160 | Epistaxis (HP:0000421) | 1.81760296 |
161 | Recurrent sinusitis (HP:0011108) | 1.79337756 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BUB1 | 3.18509011 |
2 | EIF2AK1 | 3.07940098 |
3 | MAP4K1 | 3.07468082 |
4 | WEE1 | 2.97773511 |
5 | NME2 | 2.96847359 |
6 | CDC7 | 2.52202324 |
7 | STK16 | 2.45003964 |
8 | BLK | 2.42732389 |
9 | KIT | 2.24742738 |
10 | EIF2AK3 | 2.24261455 |
11 | SCYL2 | 2.09972935 |
12 | PIM2 | 2.08832299 |
13 | BMPR2 | 1.96577062 |
14 | FLT3 | 1.84538060 |
15 | TESK2 | 1.81080267 |
16 | NEK2 | 1.79341774 |
17 | ACVR1B | 1.73712872 |
18 | RPS6KA4 | 1.72967232 |
19 | TAOK2 | 1.70714897 |
20 | TSSK6 | 1.67447159 |
21 | TEC | 1.64960070 |
22 | CSF1R | 1.61775384 |
23 | GRK7 | 1.61632827 |
24 | IRAK4 | 1.60579347 |
25 | MAP3K3 | 1.58721850 |
26 | BTK | 1.57073341 |
27 | VRK1 | 1.56362647 |
28 | BRSK2 | 1.55179328 |
29 | ZAP70 | 1.52943968 |
30 | STK10 | 1.50609609 |
31 | VRK2 | 1.48515599 |
32 | TYK2 | 1.47594096 |
33 | FGR | 1.45703122 |
34 | SYK | 1.40039418 |
35 | TNK2 | 1.38317265 |
36 | TLK1 | 1.37772889 |
37 | KDR | 1.36463714 |
38 | RPS6KB2 | 1.35691391 |
39 | EEF2K | 1.33589373 |
40 | ERN1 | 1.31286177 |
41 | LRRK2 | 1.29358143 |
42 | ATR | 1.26474442 |
43 | CDK7 | 1.25019968 |
44 | TBK1 | 1.24664057 |
45 | ARAF | 1.24070413 |
46 | PIM1 | 1.23934461 |
47 | MAP2K3 | 1.21201202 |
48 | GRK6 | 1.20750724 |
49 | DYRK3 | 1.13905903 |
50 | PRPF4B | 1.12128923 |
51 | PLK1 | 1.11322540 |
52 | SRPK1 | 1.10959959 |
53 | PAK4 | 1.10892173 |
54 | TAOK3 | 1.10084698 |
55 | NEK1 | 1.06963619 |
56 | JAK3 | 1.04651449 |
57 | CDK4 | 1.02661189 |
58 | AURKB | 1.01985789 |
59 | LYN | 1.01124773 |
60 | MAPKAPK3 | 1.01044814 |
61 | MARK3 | 0.98709925 |
62 | JAK2 | 0.98365321 |
63 | MATK | 0.97282276 |
64 | IRAK2 | 0.97112612 |
65 | MAP3K12 | 0.96134198 |
66 | TXK | 0.95907811 |
67 | TGFBR2 | 0.95654237 |
68 | TAOK1 | 0.95359694 |
69 | MAP3K11 | 0.95081560 |
70 | MAP3K13 | 0.94952536 |
71 | MAP3K8 | 0.94304824 |
72 | TTK | 0.93166801 |
73 | MAP3K14 | 0.90918476 |
74 | SIK3 | 0.90568412 |
75 | TGFBR1 | 0.86581978 |
76 | IRAK3 | 0.86230276 |
77 | PASK | 0.85122509 |
78 | MAP3K10 | 0.84575218 |
79 | MAP3K1 | 0.83866241 |
80 | ITK | 0.83154696 |
81 | STK4 | 0.82615336 |
82 | IKBKB | 0.82084111 |
83 | EIF2AK2 | 0.80404715 |
84 | JAK1 | 0.80383269 |
85 | AURKA | 0.80089055 |
86 | MAP4K2 | 0.79496150 |
87 | MAP3K5 | 0.79412671 |
88 | MST4 | 0.79285042 |
89 | CLK1 | 0.77561350 |
90 | PLK4 | 0.76332790 |
91 | MOS | 0.74844546 |
92 | LCK | 0.74068560 |
93 | TESK1 | 0.73784639 |
94 | CDK19 | 0.73770637 |
95 | CHEK2 | 0.73157855 |
96 | ZAK | 0.71386484 |
97 | CSK | 0.71299583 |
98 | RIPK4 | 0.70663259 |
99 | ABL2 | 0.67949660 |
100 | ADRBK2 | 0.65954192 |
101 | MKNK1 | 0.65788873 |
102 | BCKDK | 0.65143618 |
103 | BRSK1 | 0.64685484 |
104 | IKBKE | 0.64212908 |
105 | PKN2 | 0.62744263 |
106 | DAPK1 | 0.60477437 |
107 | LIMK1 | 0.59668712 |
108 | CDK8 | 0.57934021 |
109 | CCNB1 | 0.57613248 |
110 | IRAK1 | 0.55219598 |
111 | YES1 | 0.54599122 |
112 | CDK6 | 0.53337368 |
113 | FES | 0.52899512 |
114 | HCK | 0.52001250 |
115 | CHEK1 | 0.51854006 |
116 | * CSNK2A2 | 0.51450154 |
117 | * CSNK2A1 | 0.50450623 |
118 | PLK3 | 0.49535067 |
119 | CHUK | 0.47837320 |
120 | PRKCI | 0.47698851 |
121 | DAPK3 | 0.47634141 |
122 | CAMKK2 | 0.46455067 |
123 | PAK1 | 0.46383286 |
124 | PDK1 | 0.45581514 |
125 | PRKCQ | 0.45252611 |
126 | RPS6KA6 | 0.44640739 |
127 | RAF1 | 0.44394870 |
128 | MAP3K6 | 0.44007357 |
129 | RPS6KA5 | 0.42906833 |
130 | MAPK4 | 0.41541445 |
131 | GRK5 | 0.41156936 |
132 | DAPK2 | 0.40116000 |
133 | MAPKAPK2 | 0.40101005 |
134 | ABL1 | 0.39721156 |
135 | PRKCD | 0.39554592 |
136 | DDR2 | 0.39261852 |
137 | EPHB1 | 0.38253009 |
138 | CDK2 | 0.37922865 |
139 | MAP2K6 | 0.32374186 |
140 | ALK | 0.32026356 |
141 | PDPK1 | 0.31983272 |
142 | PIK3CG | 0.31358204 |
143 | FYN | 0.31291396 |
144 | KSR2 | 0.26402327 |
145 | SMG1 | 0.25520242 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 4.83636171 |
2 | Mismatch repair_Homo sapiens_hsa03430 | 3.90233401 |
3 | Ribosome_Homo sapiens_hsa03010 | 3.74831426 |
4 | Proteasome_Homo sapiens_hsa03050 | 3.15030775 |
5 | Base excision repair_Homo sapiens_hsa03410 | 3.08679326 |
6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.00081530 |
7 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.84464905 |
8 | Homologous recombination_Homo sapiens_hsa03440 | 2.60642160 |
9 | RNA polymerase_Homo sapiens_hsa03020 | 2.59910493 |
10 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.55848381 |
11 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.49120147 |
12 | Spliceosome_Homo sapiens_hsa03040 | 2.43047876 |
13 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 2.42662439 |
14 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.36647483 |
15 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.33999327 |
16 | RNA transport_Homo sapiens_hsa03013 | 2.10326695 |
17 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.00231878 |
18 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.89843118 |
19 | Cell cycle_Homo sapiens_hsa04110 | 1.85546360 |
20 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.81316641 |
21 | * Viral myocarditis_Homo sapiens_hsa05416 | 1.74174232 |
22 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.69431817 |
23 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.56915373 |
24 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.52111495 |
25 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.43077014 |
26 | * p53 signaling pathway_Homo sapiens_hsa04115 | 1.31563795 |
27 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.30260654 |
28 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.23017941 |
29 | Leishmaniasis_Homo sapiens_hsa05140 | 1.21566301 |
30 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.20187646 |
31 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.20132128 |
32 | Legionellosis_Homo sapiens_hsa05134 | 1.19692438 |
33 | RNA degradation_Homo sapiens_hsa03018 | 1.15665245 |
34 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.13617106 |
35 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.10781102 |
36 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.10254344 |
37 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.10091464 |
38 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.06563556 |
39 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.04001285 |
40 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.03856076 |
41 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.01188824 |
42 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.01065205 |
43 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.00511118 |
44 | Purine metabolism_Homo sapiens_hsa00230 | 1.00070473 |
45 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.99433458 |
46 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.96843496 |
47 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.95918550 |
48 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.95856316 |
49 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.95471668 |
50 | Other glycan degradation_Homo sapiens_hsa00511 | 0.95046351 |
51 | Basal transcription factors_Homo sapiens_hsa03022 | 0.95008221 |
52 | Measles_Homo sapiens_hsa05162 | 0.94558634 |
53 | Shigellosis_Homo sapiens_hsa05131 | 0.92594016 |
54 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.92112598 |
55 | Parkinsons disease_Homo sapiens_hsa05012 | 0.92011047 |
56 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.91458663 |
57 | Sulfur relay system_Homo sapiens_hsa04122 | 0.91164077 |
58 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.90339611 |
59 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.85647048 |
60 | * Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.84524959 |
61 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.80480053 |
62 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.80346791 |
63 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.74987227 |
64 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.74826989 |
65 | Allograft rejection_Homo sapiens_hsa05330 | 0.74097378 |
66 | Hepatitis C_Homo sapiens_hsa05160 | 0.73246269 |
67 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.72668113 |
68 | * Apoptosis_Homo sapiens_hsa04210 | 0.72134190 |
69 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.69049118 |
70 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.68217546 |
71 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.66519436 |
72 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.65388538 |
73 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.65049921 |
74 | * Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.65009687 |
75 | Protein export_Homo sapiens_hsa03060 | 0.62497861 |
76 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.62217026 |
77 | Influenza A_Homo sapiens_hsa05164 | 0.61626463 |
78 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.61181110 |
79 | Pertussis_Homo sapiens_hsa05133 | 0.58922931 |
80 | Hepatitis B_Homo sapiens_hsa05161 | 0.58748682 |
81 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.58154053 |
82 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.54635509 |
83 | Carbon metabolism_Homo sapiens_hsa01200 | 0.53992179 |
84 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.53559145 |
85 | * Tuberculosis_Homo sapiens_hsa05152 | 0.53493185 |
86 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.53245829 |
87 | Asthma_Homo sapiens_hsa05310 | 0.53087120 |
88 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.52674059 |
89 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.52667478 |
90 | Platelet activation_Homo sapiens_hsa04611 | 0.51701072 |
91 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.51191100 |
92 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.50894758 |
93 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.48856460 |
94 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.48707480 |
95 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.48095164 |
96 | Lysosome_Homo sapiens_hsa04142 | 0.46109652 |
97 | Malaria_Homo sapiens_hsa05144 | 0.45572203 |
98 | HTLV-I infection_Homo sapiens_hsa05166 | 0.44842843 |
99 | Galactose metabolism_Homo sapiens_hsa00052 | 0.44657615 |
100 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.43743682 |
101 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.43145040 |
102 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.43074830 |
103 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.41438135 |
104 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.41391665 |
105 | Alzheimers disease_Homo sapiens_hsa05010 | 0.41103083 |
106 | Bladder cancer_Homo sapiens_hsa05219 | 0.40555367 |
107 | Phagosome_Homo sapiens_hsa04145 | 0.39127930 |
108 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.37954414 |
109 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.36688373 |
110 | Thyroid cancer_Homo sapiens_hsa05216 | 0.36046139 |
111 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.35195019 |
112 | Salmonella infection_Homo sapiens_hsa05132 | 0.33957717 |
113 | Huntingtons disease_Homo sapiens_hsa05016 | 0.33605340 |
114 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.33426532 |
115 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.33271852 |
116 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.33047663 |
117 | Endocytosis_Homo sapiens_hsa04144 | 0.31873569 |
118 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.31822172 |
119 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.31136440 |
120 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.30868715 |
121 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.29275273 |
122 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.28386117 |
123 | * Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.27928491 |
124 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.27690183 |
125 | * Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.26878566 |
126 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.26611342 |
127 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.26184548 |
128 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.25749282 |
129 | Metabolic pathways_Homo sapiens_hsa01100 | 0.25021478 |
130 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.22265855 |
131 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.16639004 |
132 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.16155788 |
133 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.15475217 |
134 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.14697860 |
135 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.14379238 |