BIVM

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)5.10332677
2neuron cell-cell adhesion (GO:0007158)4.85320109
3presynaptic membrane assembly (GO:0097105)4.84485328
4serotonin receptor signaling pathway (GO:0007210)4.49019094
5axonal fasciculation (GO:0007413)4.34448635
6postsynaptic membrane organization (GO:0001941)4.15142277
7cell migration in hindbrain (GO:0021535)4.13202949
8central nervous system projection neuron axonogenesis (GO:0021952)4.07604860
9behavioral response to nicotine (GO:0035095)4.05346155
10presynaptic membrane organization (GO:0097090)4.00670294
11negative regulation of synaptic transmission, GABAergic (GO:0032229)3.86022429
12neuron recognition (GO:0008038)3.84986342
13nucleobase catabolic process (GO:0046113)3.83630324
14glial cell proliferation (GO:0014009)3.80658890
15regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.77022320
16apical protein localization (GO:0045176)3.57732549
17layer formation in cerebral cortex (GO:0021819)3.52149803
18vocalization behavior (GO:0071625)3.48588560
19dorsal/ventral axis specification (GO:0009950)3.30027790
20synaptic vesicle endocytosis (GO:0048488)3.25622960
21dendrite morphogenesis (GO:0048813)3.24422049
22regulation of dendritic spine morphogenesis (GO:0061001)3.20788677
23positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.18502318
24establishment of mitochondrion localization (GO:0051654)3.18171711
25ubiquinone biosynthetic process (GO:0006744)3.17384106
26regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.16581753
27dendritic spine morphogenesis (GO:0060997)3.15988381
28axon extension (GO:0048675)3.15031086
29protein-cofactor linkage (GO:0018065)3.13883165
30glutamate secretion (GO:0014047)3.13684635
31neurotransmitter-gated ion channel clustering (GO:0072578)3.08113446
32gamma-aminobutyric acid transport (GO:0015812)3.07509692
33auditory behavior (GO:0031223)3.06898521
34establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.05231558
35mitochondrion transport along microtubule (GO:0047497)3.05231558
36central nervous system neuron axonogenesis (GO:0021955)3.04684542
37limb bud formation (GO:0060174)3.00572087
38response to pheromone (GO:0019236)2.98525898
39ubiquinone metabolic process (GO:0006743)2.97870059
40membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.94802570
41regulation of hippo signaling (GO:0035330)2.94055809
42positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.92434402
43protein localization to cilium (GO:0061512)2.92196194
44hippocampus development (GO:0021766)2.89433881
45proximal/distal pattern formation (GO:0009954)2.89054272
46regulation of glutamate receptor signaling pathway (GO:1900449)2.86876122
47erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.86109949
48L-phenylalanine catabolic process (GO:0006559)2.86109949
49neuronal action potential (GO:0019228)2.83232598
50asymmetric protein localization (GO:0008105)2.82862952
51regulation of action potential (GO:0098900)2.82744242
52glucocorticoid receptor signaling pathway (GO:0042921)2.81830527
53regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.79251711
54cerebral cortex radially oriented cell migration (GO:0021799)2.77708283
55synaptic vesicle exocytosis (GO:0016079)2.76877722
56ketone body metabolic process (GO:1902224)2.76401797
57reflex (GO:0060004)2.76099458
58dendrite development (GO:0016358)2.75368809
59regulation of dendrite morphogenesis (GO:0048814)2.74461350
60negative regulation of dendrite morphogenesis (GO:0050774)2.73906956
61glycosphingolipid biosynthetic process (GO:0006688)2.72358012
62gamma-aminobutyric acid signaling pathway (GO:0007214)2.71515182
63startle response (GO:0001964)2.70997646
64negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.69460755
65DNA double-strand break processing (GO:0000729)2.67570231
66synaptic vesicle docking involved in exocytosis (GO:0016081)2.66360550
67kidney morphogenesis (GO:0060993)2.66178678
68olfactory bulb development (GO:0021772)2.65967935
69negative regulation of microtubule polymerization (GO:0031115)2.65490674
70membrane assembly (GO:0071709)2.62929198
71positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.62434091
72quinone biosynthetic process (GO:1901663)2.62401589
73neuronal action potential propagation (GO:0019227)2.61479605
74regulation of DNA endoreduplication (GO:0032875)2.60310927
75anatomical structure arrangement (GO:0048532)2.59818011
76neuron projection extension (GO:1990138)2.58397816
77mechanosensory behavior (GO:0007638)2.58312164
78negative regulation of dendrite development (GO:2000171)2.55980608
79DNA unwinding involved in DNA replication (GO:0006268)2.55850302
80tryptophan catabolic process (GO:0006569)2.55343119
81indole-containing compound catabolic process (GO:0042436)2.55343119
82indolalkylamine catabolic process (GO:0046218)2.55343119
83innervation (GO:0060384)2.55320043
84midgut development (GO:0007494)2.55161789
85erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)2.54757726
86L-phenylalanine metabolic process (GO:0006558)2.54757726
87kynurenine metabolic process (GO:0070189)2.54289884
88neural tube formation (GO:0001841)2.53494792
89membrane depolarization during action potential (GO:0086010)2.53314732
90behavioral response to ethanol (GO:0048149)2.53112757
91mitotic sister chromatid cohesion (GO:0007064)2.53063168
92membrane hyperpolarization (GO:0060081)2.52502499
93negative regulation of cytosolic calcium ion concentration (GO:0051481)2.52191910
94protein complex biogenesis (GO:0070271)2.50436166
95NADH dehydrogenase complex assembly (GO:0010257)2.49427077
96mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.49427077
97mitochondrial respiratory chain complex I assembly (GO:0032981)2.49427077
98detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.49366896
99protein localization to synapse (GO:0035418)2.46867337
100positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc2.46512506
101paraxial mesoderm development (GO:0048339)2.46124105
102water-soluble vitamin biosynthetic process (GO:0042364)2.45876522
103positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.45593215
104hindbrain development (GO:0030902)2.45041717
105glycerophospholipid catabolic process (GO:0046475)2.44627034
106lateral sprouting from an epithelium (GO:0060601)2.44558491
107cerebellar granule cell differentiation (GO:0021707)2.44449949
108regulation of glycogen (starch) synthase activity (GO:2000465)2.44244139
109corticosteroid receptor signaling pathway (GO:0031958)2.44042259
110neurotransmitter secretion (GO:0007269)2.43246866
111regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.42475200
112establishment of nucleus localization (GO:0040023)2.42009008
113protein targeting to vacuole (GO:0006623)2.41744160
114protein targeting to lysosome (GO:0006622)2.41744160
115establishment of protein localization to vacuole (GO:0072666)2.41744160
116long-term synaptic potentiation (GO:0060291)2.41666480
117regulation of NFAT protein import into nucleus (GO:0051532)2.40735102
118axonogenesis (GO:0007409)2.39899452
119protein polyglutamylation (GO:0018095)2.39270009
120regulation of synaptic vesicle exocytosis (GO:2000300)2.38916587
121righting reflex (GO:0060013)2.38837734
122C4-dicarboxylate transport (GO:0015740)2.38570791
123synaptic transmission, glutamatergic (GO:0035249)2.38329098
124regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)2.37417058
125neuron-neuron synaptic transmission (GO:0007270)2.36618855
126positive regulation of mitochondrial fission (GO:0090141)2.36553799
127organelle transport along microtubule (GO:0072384)2.36217593
128synaptic transmission, cholinergic (GO:0007271)2.35757934
129regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.35310035
130preassembly of GPI anchor in ER membrane (GO:0016254)2.35249626
131regulation of gene expression by genetic imprinting (GO:0006349)2.34413204
132negative regulation of neurotransmitter secretion (GO:0046929)2.33862180
133negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)2.32968900
134regulation of transmission of nerve impulse (GO:0051969)2.32463064
135retinal ganglion cell axon guidance (GO:0031290)2.32295545
136regulation of cell communication by electrical coupling (GO:0010649)2.32199803
137branched-chain amino acid catabolic process (GO:0009083)2.31641711
138positive regulation of synapse assembly (GO:0051965)2.30619190
139regulation of neurotransmitter uptake (GO:0051580)2.30286581
140regulation of synapse structural plasticity (GO:0051823)2.30259488
141negative regulation of stem cell proliferation (GO:2000647)2.29950277
142synapse assembly (GO:0007416)2.29842118
143platelet dense granule organization (GO:0060155)2.29314495
144lipid particle organization (GO:0034389)2.29276688
145mitochondrial respiratory chain complex assembly (GO:0033108)2.29213391
146inner ear receptor stereocilium organization (GO:0060122)2.28739984
147regulation of long-term neuronal synaptic plasticity (GO:0048169)2.27027392
148neurotransmitter catabolic process (GO:0042135)2.26793794
149nuclear pore complex assembly (GO:0051292)2.25414378
150magnesium ion transport (GO:0015693)2.25347012
151intraciliary transport (GO:0042073)2.24357984
152negative regulation of neurotransmitter transport (GO:0051589)2.23857868
153ionotropic glutamate receptor signaling pathway (GO:0035235)2.23650132
154negative regulation of axon extension involved in axon guidance (GO:0048843)2.23533026
155glutamate receptor signaling pathway (GO:0007215)2.23469293
156regulation of skeletal muscle contraction (GO:0014819)2.22560608
157replicative senescence (GO:0090399)2.22551978
158neuromuscular synaptic transmission (GO:0007274)2.22318166
159organelle disassembly (GO:1903008)2.22206412
160positive regulation of dendrite morphogenesis (GO:0050775)2.22147029
161dicarboxylic acid catabolic process (GO:0043649)2.22094098
162cellular ketone body metabolic process (GO:0046950)2.22079751
163cilium morphogenesis (GO:0060271)2.21179221
164negative regulation of calcium ion transmembrane transport (GO:1903170)2.20509765
165negative regulation of calcium ion transmembrane transporter activity (GO:1901020)2.20509765
166regulation of short-term neuronal synaptic plasticity (GO:0048172)2.19734052
167negative regulation of fibroblast apoptotic process (GO:2000270)2.18914605
168negative regulation of protein localization to cell surface (GO:2000009)2.18855249
169cilium organization (GO:0044782)2.18605998
170synaptic vesicle maturation (GO:0016188)2.17944099
171action potential (GO:0001508)2.16583208
172nonmotile primary cilium assembly (GO:0035058)2.15707037
173neurotransmitter metabolic process (GO:0042133)2.15282347
174G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.15065278
175benzene-containing compound metabolic process (GO:0042537)2.14722537
176cilium assembly (GO:0042384)2.14284362
177tryptophan metabolic process (GO:0006568)2.11259981
178aldehyde catabolic process (GO:0046185)2.10712455
179detection of calcium ion (GO:0005513)2.10695679
180inositol metabolic process (GO:0006020)2.10613801
181calcium ion import (GO:0070509)2.09727615

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human3.65099837
2RBPJ_22232070_ChIP-Seq_NCS_Mouse3.55251220
3SALL1_21062744_ChIP-ChIP_HESCs_Human3.53448298
4EZH2_22144423_ChIP-Seq_EOC_Human3.28452470
5TAF15_26573619_Chip-Seq_HEK293_Human3.05724394
6GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.99716100
7CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.62008472
8NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.60370959
9WT1_19549856_ChIP-ChIP_CCG9911_Human2.38462101
10CTBP2_25329375_ChIP-Seq_LNCAP_Human2.32143304
11FUS_26573619_Chip-Seq_HEK293_Human2.29607846
12VDR_22108803_ChIP-Seq_LS180_Human2.27216582
13HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.19930444
14POU3F2_20337985_ChIP-ChIP_501MEL_Human2.15237301
15P300_19829295_ChIP-Seq_ESCs_Human2.08315608
16ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.07001806
17OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.99785916
18* FLI1_27457419_Chip-Seq_LIVER_Mouse1.97381452
19EWS_26573619_Chip-Seq_HEK293_Human1.95934781
20GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.93905737
21PIAS1_25552417_ChIP-Seq_VCAP_Human1.93696181
22SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.93253525
23CTBP1_25329375_ChIP-Seq_LNCAP_Human1.92692354
24SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.92447715
25E2F7_22180533_ChIP-Seq_HELA_Human1.86836144
26KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.81638459
27SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.80096033
28SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.78193521
29SMAD4_21799915_ChIP-Seq_A2780_Human1.77349331
30ZFP57_27257070_Chip-Seq_ESCs_Mouse1.75960085
31PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.75356040
32* PCGF2_27294783_Chip-Seq_ESCs_Mouse1.70737284
33SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.70547707
34IGF1R_20145208_ChIP-Seq_DFB_Human1.65527166
35FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.63666609
36AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.61695542
37TOP2B_26459242_ChIP-Seq_MCF-7_Human1.58342899
38TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.55482475
39SOX2_21211035_ChIP-Seq_LN229_Gbm1.54584720
40JARID2_20064375_ChIP-Seq_MESCs_Mouse1.54015537
41ZNF217_24962896_ChIP-Seq_MCF-7_Human1.52703207
42EZH2_27304074_Chip-Seq_ESCs_Mouse1.52191845
43PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.50985579
44* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.49097518
45RNF2_27304074_Chip-Seq_NSC_Mouse1.48596496
46MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.47229489
47STAT3_23295773_ChIP-Seq_U87_Human1.47095080
48SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.46703607
49IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.45741227
50CBP_20019798_ChIP-Seq_JUKART_Human1.45741227
51SMAD3_21741376_ChIP-Seq_EPCs_Human1.44808471
52EED_16625203_ChIP-ChIP_MESCs_Mouse1.43280883
53RNF2_18974828_ChIP-Seq_MESCs_Mouse1.42738863
54EZH2_18974828_ChIP-Seq_MESCs_Mouse1.42738863
55SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.42362521
56ER_23166858_ChIP-Seq_MCF-7_Human1.41751158
57UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.40993702
58NR3C1_21868756_ChIP-Seq_MCF10A_Human1.40641837
59CDX2_19796622_ChIP-Seq_MESCs_Mouse1.38071931
60NANOG_18555785_Chip-Seq_ESCs_Mouse1.37665411
61BMI1_23680149_ChIP-Seq_NPCS_Mouse1.36754611
62* SUZ12_27294783_Chip-Seq_NPCs_Mouse1.36531036
63* SOX9_26525672_Chip-Seq_HEART_Mouse1.35693121
64SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.35523720
65RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.35472225
66* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.34646843
67ZNF274_21170338_ChIP-Seq_K562_Hela1.32969413
68ESR1_15608294_ChIP-ChIP_MCF-7_Human1.32640989
69PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.31436619
70SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.30118260
71JARID2_20075857_ChIP-Seq_MESCs_Mouse1.29584204
72NRF2_20460467_ChIP-Seq_MEFs_Mouse1.28208945
73NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.28208945
74* EZH2_27294783_Chip-Seq_NPCs_Mouse1.28140919
75STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.27063784
76* P53_22387025_ChIP-Seq_ESCs_Mouse1.25722638
77AR_21572438_ChIP-Seq_LNCaP_Human1.25584149
78TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.25084959
79POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.25084959
80* ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.24584684
81GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.23132628
82* NFE2_27457419_Chip-Seq_LIVER_Mouse1.22726648
83MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.21751872
84CBX2_27304074_Chip-Seq_ESCs_Mouse1.20711950
85EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.20481516
86FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.20043475
87TP53_22573176_ChIP-Seq_HFKS_Human1.19332781
88BCAT_22108803_ChIP-Seq_LS180_Human1.19008363
89NR3C1_23031785_ChIP-Seq_PC12_Mouse1.18892412
90E2F1_18555785_Chip-Seq_ESCs_Mouse1.18888501
91* PCGF2_27294783_Chip-Seq_NPCs_Mouse1.17952763
92SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.17801753
93REST_21632747_ChIP-Seq_MESCs_Mouse1.17636910
94PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.16990855
95* AR_19668381_ChIP-Seq_PC3_Human1.16950529
96* TCF4_23295773_ChIP-Seq_U87_Human1.16406930
97RNF2_27304074_Chip-Seq_ESCs_Mouse1.16397628
98TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.16265980
99RUNX2_22187159_ChIP-Seq_PCA_Human1.15718533
100CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.14977002
101JUN_21703547_ChIP-Seq_K562_Human1.14857324
102POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.13282995
103* SUZ12_18555785_Chip-Seq_ESCs_Mouse1.12766089
104TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12256693
105RING1B_27294783_Chip-Seq_NPCs_Mouse1.12069448
106MYC_18940864_ChIP-ChIP_HL60_Human1.11625823
107WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.11169325
108TAL1_26923725_Chip-Seq_HPCs_Mouse1.11021306
109* RARB_27405468_Chip-Seq_BRAIN_Mouse1.10449237
110TBX3_20139965_ChIP-Seq_MESCs_Mouse1.10351121
111TBX3_20139965_ChIP-Seq_ESCs_Mouse1.10162339
112TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.10107303
113YAP1_20516196_ChIP-Seq_MESCs_Mouse1.09404963
114POU5F1_16153702_ChIP-ChIP_HESCs_Human1.08790353
115* STAT3_18555785_Chip-Seq_ESCs_Mouse1.08583568
116FLI1_21867929_ChIP-Seq_TH2_Mouse1.08138754
117TP53_18474530_ChIP-ChIP_U2OS_Human1.08075071
118NANOG_19829295_ChIP-Seq_ESCs_Human1.07989473
119SOX2_19829295_ChIP-Seq_ESCs_Human1.07989473
120* EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.07329523
121RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.06678188
122* CMYC_18555785_Chip-Seq_ESCs_Mouse1.06469410
123SMAD_19615063_ChIP-ChIP_OVARY_Human1.05433057
124* CRX_20693478_ChIP-Seq_RETINA_Mouse1.05242926
125KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.05040515
126TP53_16413492_ChIP-PET_HCT116_Human1.04906711
127KDM2B_26808549_Chip-Seq_REH_Human1.04718168
128TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.04681580
129SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.04532981
130AR_25329375_ChIP-Seq_VCAP_Human1.03815873
131HTT_18923047_ChIP-ChIP_STHdh_Human1.03373529
132* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.02291707
133REST_18959480_ChIP-ChIP_MESCs_Mouse1.02252457
134TCF4_22108803_ChIP-Seq_LS180_Human1.01851543
135P300_18555785_Chip-Seq_ESCs_Mouse1.01157528
136IRF1_19129219_ChIP-ChIP_H3396_Human1.00665988
137MTF2_20144788_ChIP-Seq_MESCs_Mouse1.00054056
138POU3F1_26484290_ChIP-Seq_ESCss_Mouse0.99837785
139KLF5_20875108_ChIP-Seq_MESCs_Mouse0.98778130
140TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.97199993
141SOX2_18555785_Chip-Seq_ESCs_Mouse0.96536675
142BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.96254646

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000537_abnormal_urethra_morphology4.13514234
2MP0003787_abnormal_imprinting2.89011873
3MP0004885_abnormal_endolymph2.86392742
4MP0000778_abnormal_nervous_system2.86334133
5MP0004859_abnormal_synaptic_plasticity2.53331518
6MP0003880_abnormal_central_pattern2.45579552
7MP0005645_abnormal_hypothalamus_physiol2.41840630
8MP0004145_abnormal_muscle_electrophysio2.33062007
9MP0010386_abnormal_urinary_bladder2.29918132
10MP0004147_increased_porphyrin_level2.11193743
11MP0000013_abnormal_adipose_tissue2.04898879
12MP0004215_abnormal_myocardial_fiber2.04316725
13MP0008789_abnormal_olfactory_epithelium1.98541364
14MP0002735_abnormal_chemical_nociception1.95923906
15MP0004270_analgesia1.94382204
16MP0003635_abnormal_synaptic_transmissio1.91505309
17MP0003121_genomic_imprinting1.89898794
18MP0010030_abnormal_orbit_morphology1.86818181
19MP0003890_abnormal_embryonic-extraembry1.82873181
20MP0005394_taste/olfaction_phenotype1.80893108
21MP0005499_abnormal_olfactory_system1.80893108
22MP0006072_abnormal_retinal_apoptosis1.75455791
23MP0002837_dystrophic_cardiac_calcinosis1.73416418
24MP0005646_abnormal_pituitary_gland1.72717426
25MP0001984_abnormal_olfaction1.70896686
26MP0002184_abnormal_innervation1.67955059
27MP0004142_abnormal_muscle_tone1.67779720
28MP0001177_atelectasis1.64054298
29MP0002063_abnormal_learning/memory/cond1.63745514
30MP0001188_hyperpigmentation1.61880072
31MP0005551_abnormal_eye_electrophysiolog1.60969198
32MP0005187_abnormal_penis_morphology1.59858674
33MP0002733_abnormal_thermal_nociception1.58607211
34MP0004084_abnormal_cardiac_muscle1.55154492
35MP0002233_abnormal_nose_morphology1.54742191
36MP0004043_abnormal_pH_regulation1.54589173
37MP0005408_hypopigmentation1.53554155
38MP0002638_abnormal_pupillary_reflex1.53535201
39MP0000534_abnormal_ureter_morphology1.50744138
40MP0002734_abnormal_mechanical_nocicepti1.46569456
41MP0009697_abnormal_copulation1.46291139
42MP0008875_abnormal_xenobiotic_pharmacok1.46256737
43MP0002822_catalepsy1.45222067
44MP0001529_abnormal_vocalization1.43540135
45MP0008775_abnormal_heart_ventricle1.42376048
46MP0003646_muscle_fatigue1.41459734
47MP0002938_white_spotting1.41283180
48MP0002876_abnormal_thyroid_physiology1.39645131
49MP0001486_abnormal_startle_reflex1.38219930
50MP0001485_abnormal_pinna_reflex1.37921270
51MP0004742_abnormal_vestibular_system1.37505088
52MP0003385_abnormal_body_wall1.37084263
53MP0003937_abnormal_limbs/digits/tail_de1.36562756
54MP0001905_abnormal_dopamine_level1.36291762
55MP0009046_muscle_twitch1.35335819
56MP0005253_abnormal_eye_physiology1.33742218
57MP0009384_cardiac_valve_regurgitation1.31383618
58MP0005423_abnormal_somatic_nervous1.31174881
59MP0001970_abnormal_pain_threshold1.30858349
60MP0009745_abnormal_behavioral_response1.30757296
61MP0001501_abnormal_sleep_pattern1.30315550
62MP0002064_seizures1.29792404
63MP0004133_heterotaxia1.28412829
64MP0004811_abnormal_neuron_physiology1.28380282
65MP0003252_abnormal_bile_duct1.28254398
66MP0003861_abnormal_nervous_system1.28155575
67MP0003123_paternal_imprinting1.23853514
68MP0000751_myopathy1.23344517
69MP0002102_abnormal_ear_morphology1.23092384
70MP0005084_abnormal_gallbladder_morpholo1.22386519
71MP0003755_abnormal_palate_morphology1.21963649
72MP0006292_abnormal_olfactory_placode1.21833159
73MP0008872_abnormal_physiological_respon1.21358713
74MP0009379_abnormal_foot_pigmentation1.20596769
75MP0002572_abnormal_emotion/affect_behav1.20124938
76MP0001299_abnormal_eye_distance/1.18672954
77MP0002152_abnormal_brain_morphology1.18463824
78MP0009780_abnormal_chondrocyte_physiolo1.18213522
79MP0004924_abnormal_behavior1.16330071
80MP0005386_behavior/neurological_phenoty1.16330071
81MP0006276_abnormal_autonomic_nervous1.15885494
82MP0000569_abnormal_digit_pigmentation1.15624651
83MP0002139_abnormal_hepatobiliary_system1.15437540
84MP0002234_abnormal_pharynx_morphology1.15412007
85MP0004233_abnormal_muscle_weight1.14489654
86MP0009053_abnormal_anal_canal1.14052693
87MP0002272_abnormal_nervous_system1.13846121
88MP0000372_irregular_coat_pigmentation1.11361740
89MP0000631_abnormal_neuroendocrine_gland1.10756861
90MP0003122_maternal_imprinting1.09728417
91MP0000749_muscle_degeneration1.09014161
92MP0005248_abnormal_Harderian_gland1.08676475
93MP0000516_abnormal_urinary_system1.08524461
94MP0005367_renal/urinary_system_phenotyp1.08524461
95MP0002177_abnormal_outer_ear1.07575766
96MP0003942_abnormal_urinary_system1.06643534
97MP0005623_abnormal_meninges_morphology1.05192780
98MP0002160_abnormal_reproductive_system1.05184649
99MP0002882_abnormal_neuron_morphology1.04741046
100MP0001968_abnormal_touch/_nociception1.04460232
101MP0002751_abnormal_autonomic_nervous1.04341606
102MP0003195_calcinosis1.03569378
103MP0004085_abnormal_heartbeat1.00970730
104MP0002557_abnormal_social/conspecific_i1.00796669
105MP0002090_abnormal_vision0.99316675
106MP0001293_anophthalmia0.97244650
107MP0002067_abnormal_sensory_capabilities0.97213348
108MP0003567_abnormal_fetal_cardiomyocyte0.96150315
109MP0000538_abnormal_urinary_bladder0.96063169
110MP0005620_abnormal_muscle_contractility0.95087081
111MP0000955_abnormal_spinal_cord0.94889595
112MP0005332_abnormal_amino_acid0.92856587
113MP0002081_perinatal_lethality0.91968858
114MP0003632_abnormal_nervous_system0.91638560
115MP0004484_altered_response_of0.90971238
116MP0005360_urolithiasis0.90921961
117MP0002736_abnormal_nociception_after0.90441270
118MP0005379_endocrine/exocrine_gland_phen0.90367783
119MP0001502_abnormal_circadian_rhythm0.89376933
120MP0002909_abnormal_adrenal_gland0.88070501
121MP0003137_abnormal_impulse_conducting0.87592589
122MP0005171_absent_coat_pigmentation0.87520436
123MP0002653_abnormal_ependyma_morphology0.87308942
124MP0000230_abnormal_systemic_arterial0.86512876
125MP0003119_abnormal_digestive_system0.86189941
126MP0004036_abnormal_muscle_relaxation0.85561718
127MP0004134_abnormal_chest_morphology0.85074887
128MP0003115_abnormal_respiratory_system0.84351142
129MP0008058_abnormal_DNA_repair0.84106814
130MP0002106_abnormal_muscle_physiology0.83840303
131MP0005085_abnormal_gallbladder_physiolo0.83293249
132MP0009703_decreased_birth_body0.83054167
133MP0003011_delayed_dark_adaptation0.81737881
134MP0001286_abnormal_eye_development0.81619408
135MP0002066_abnormal_motor_capabilities/c0.81007347
136MP0000049_abnormal_middle_ear0.80802439
137MP0001270_distended_abdomen0.79097824
138MP0005369_muscle_phenotype0.79026493
139MP0003283_abnormal_digestive_organ0.78999044
140MP0009250_abnormal_appendicular_skeleto0.78945284
141MP0002269_muscular_atrophy0.78696821
142MP0000428_abnormal_craniofacial_morphol0.78602006
143MP0008438_abnormal_cutaneous_collagen0.78109130
144MP0009672_abnormal_birth_weight0.77056960
145MP0005503_abnormal_tendon_morphology0.76835102
146MP0002752_abnormal_somatic_nervous0.76713499
147MP0008995_early_reproductive_senescence0.76000863
148MP0002084_abnormal_developmental_patter0.75348741
149MP0002116_abnormal_craniofacial_bone0.75230470
150MP0003938_abnormal_ear_development0.74496015

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cochlea (HP:0000375)5.21964792
2Papilledema (HP:0001085)4.01422028
3Type II lissencephaly (HP:0007260)3.92436247
4Morphological abnormality of the inner ear (HP:0011390)3.78565948
5Hyperventilation (HP:0002883)3.44320020
6Abnormality of the labia minora (HP:0012880)3.40473439
7Papillary thyroid carcinoma (HP:0002895)3.36585927
8Retinal dysplasia (HP:0007973)3.31468851
9Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)3.31422258
10Degeneration of the lateral corticospinal tracts (HP:0002314)3.31422258
11Atonic seizures (HP:0010819)3.31042384
12Nephronophthisis (HP:0000090)3.29439684
13Colon cancer (HP:0003003)3.19634262
14Pancreatic cysts (HP:0001737)3.18393076
15Abnormality of the corticospinal tract (HP:0002492)3.17894540
16True hermaphroditism (HP:0010459)3.11980257
17Volvulus (HP:0002580)3.04533203
18Pancreatic fibrosis (HP:0100732)2.90397762
19Abnormality of the renal medulla (HP:0100957)2.82625385
20Epileptic encephalopathy (HP:0200134)2.76763701
21Limb dystonia (HP:0002451)2.76189169
22Excessive salivation (HP:0003781)2.71547277
23Drooling (HP:0002307)2.71547277
24Renal cortical cysts (HP:0000803)2.70711168
25Molar tooth sign on MRI (HP:0002419)2.69932055
26Abnormality of midbrain morphology (HP:0002418)2.69932055
27Abnormality of the renal cortex (HP:0011035)2.68821263
28Absence seizures (HP:0002121)2.68513929
29Cerebellar dysplasia (HP:0007033)2.62900841
30Abnormality of oral frenula (HP:0000190)2.60795516
31Calf muscle hypertrophy (HP:0008981)2.54360354
32Gait imbalance (HP:0002141)2.53013809
33Abnormality of the astrocytes (HP:0100707)2.52095002
34Astrocytoma (HP:0009592)2.52095002
35Inability to walk (HP:0002540)2.51403652
36Lissencephaly (HP:0001339)2.47634291
37Ankyloglossia (HP:0010296)2.42793440
38Muscle hypertrophy of the lower extremities (HP:0008968)2.40039317
39Insidious onset (HP:0003587)2.38529846
40Termporal pattern (HP:0011008)2.38529846
41Increased serum pyruvate (HP:0003542)2.37013448
42Abnormality of glycolysis (HP:0004366)2.37013448
43Progressive cerebellar ataxia (HP:0002073)2.35447312
44Genital tract atresia (HP:0001827)2.34133806
45Broad-based gait (HP:0002136)2.33670941
46Amblyopia (HP:0000646)2.32776992
47Ependymoma (HP:0002888)2.32177385
48Delayed gross motor development (HP:0002194)2.32055097
49Acute necrotizing encephalopathy (HP:0006965)2.31925074
50Vaginal atresia (HP:0000148)2.29845740
51Thyroid carcinoma (HP:0002890)2.29144420
52Impaired vibration sensation in the lower limbs (HP:0002166)2.28660235
53Abnormality of alanine metabolism (HP:0010916)2.27939153
54Hyperalaninemia (HP:0003348)2.27939153
55Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.27939153
56Agitation (HP:0000713)2.25886649
57Protruding tongue (HP:0010808)2.24093003
58Progressive inability to walk (HP:0002505)2.23048818
59Fair hair (HP:0002286)2.22354209
60Febrile seizures (HP:0002373)2.21209247
61Mitochondrial inheritance (HP:0001427)2.20545029
62Methylmalonic acidemia (HP:0002912)2.19066761
63Congenital primary aphakia (HP:0007707)2.16824704
64Shoulder girdle muscle weakness (HP:0003547)2.16486320
65Hepatic necrosis (HP:0002605)2.16251932
66Urinary urgency (HP:0000012)2.14365910
67Acute encephalopathy (HP:0006846)2.13744435
68Focal motor seizures (HP:0011153)2.13363632
69Abolished electroretinogram (ERG) (HP:0000550)2.12088007
70Abnormal mitochondria in muscle tissue (HP:0008316)2.10570195
71Absent eyebrow (HP:0002223)2.10011596
72Increased CSF lactate (HP:0002490)2.05812178
73Dialeptic seizures (HP:0011146)2.05492389
74Morphological abnormality of the pyramidal tract (HP:0002062)2.04934863
75Focal seizures (HP:0007359)2.04878725
76Progressive macrocephaly (HP:0004481)2.04730237
77Biliary tract neoplasm (HP:0100574)2.03669436
78Relative macrocephaly (HP:0004482)2.03180597
79Hepatocellular necrosis (HP:0001404)2.02552807
80Increased corneal curvature (HP:0100692)2.02459939
81Keratoconus (HP:0000563)2.02459939
82Short tibia (HP:0005736)2.00776975
83Medial flaring of the eyebrow (HP:0010747)1.93427799
84Glioma (HP:0009733)1.92536487
85Muscle fiber inclusion bodies (HP:0100299)1.92374163
86Akinesia (HP:0002304)1.91440298
87Sensory axonal neuropathy (HP:0003390)1.91299555
88Severe muscular hypotonia (HP:0006829)1.91276847
89Postaxial foot polydactyly (HP:0001830)1.91241985
90Neoplasm of the thyroid gland (HP:0100031)1.90833583
91Nemaline bodies (HP:0003798)1.90813650
92Fetal akinesia sequence (HP:0001989)1.90766995
93Left ventricular hypertrophy (HP:0001712)1.89785456
94Ketoacidosis (HP:0001993)1.88782009
95Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)1.88733670
96Infantile muscular hypotonia (HP:0008947)1.88571488
97Rimmed vacuoles (HP:0003805)1.87975628
98Urinary bladder sphincter dysfunction (HP:0002839)1.87939941
99Thickened helices (HP:0000391)1.87618177
100Hemiparesis (HP:0001269)1.85267529
101Tented upper lip vermilion (HP:0010804)1.85258177
102Epileptiform EEG discharges (HP:0011182)1.83586324
103Occipital encephalocele (HP:0002085)1.83488613
104Abnormal finger flexion creases (HP:0006143)1.83199450
105Absent phalangeal crease (HP:0006109)1.82827466
106Abnormality of the calf musculature (HP:0001430)1.82051415
107Buphthalmos (HP:0000557)1.82047304
108Hypochromic microcytic anemia (HP:0004840)1.81311694
109Nephrogenic diabetes insipidus (HP:0009806)1.81196991
110Poor coordination (HP:0002370)1.80908045
111Pheochromocytoma (HP:0002666)1.80832939
112Hypobetalipoproteinemia (HP:0003563)1.80037380
113Cystic liver disease (HP:0006706)1.80031509
114Postaxial hand polydactyly (HP:0001162)1.77988261
115Type 2 muscle fiber atrophy (HP:0003554)1.76472188
116Aplasia/Hypoplasia of the tibia (HP:0005772)1.76296522
117Abnormality of salivation (HP:0100755)1.75051488
118Glycosuria (HP:0003076)1.74657361
119Abnormality of urine glucose concentration (HP:0011016)1.74657361
120Congenital hepatic fibrosis (HP:0002612)1.74136986
121Aplasia/Hypoplasia of the tongue (HP:0010295)1.73963453
122Generalized hypopigmentation of hair (HP:0011358)1.73519204
123Spastic gait (HP:0002064)1.73475149
124EEG with generalized epileptiform discharges (HP:0011198)1.73175270
125Polyphagia (HP:0002591)1.73020420
126Thyroid-stimulating hormone excess (HP:0002925)1.71399500
127Scanning speech (HP:0002168)1.71109434
128Gaze-evoked nystagmus (HP:0000640)1.70679606
129Methylmalonic aciduria (HP:0012120)1.70094331
130Absent speech (HP:0001344)1.69520176
131Tinnitus (HP:0000360)1.69292716
132Intestinal atresia (HP:0011100)1.68919972
133Hypsarrhythmia (HP:0002521)1.68837474
134Tubular atrophy (HP:0000092)1.67970823
135Myotonia (HP:0002486)1.67713826
136Pelvic girdle muscle weakness (HP:0003749)1.67323560
137Cutaneous finger syndactyly (HP:0010554)1.67172105
138Long clavicles (HP:0000890)1.66858324
139Lipid accumulation in hepatocytes (HP:0006561)1.66697605
140Pachygyria (HP:0001302)1.65966298
141Neoplasm of the small intestine (HP:0100833)1.65962278
142Specific learning disability (HP:0001328)1.65234502
143Blue irides (HP:0000635)1.65086098
144Hepatoblastoma (HP:0002884)1.64937181
145Rectal prolapse (HP:0002035)1.64301204
146Bundle branch block (HP:0011710)1.64193516
147Microglossia (HP:0000171)1.63595595
148Aqueductal stenosis (HP:0002410)1.63074461
149Sclerocornea (HP:0000647)1.62617455
150Distal arthrogryposis (HP:0005684)1.61857495
151Ketosis (HP:0001946)1.61410702
152Aplasia/Hypoplasia of the fovea (HP:0008060)1.61088828
153Bifid tongue (HP:0010297)1.59285244
154Paraplegia (HP:0010550)1.59152029
155Open mouth (HP:0000194)1.57693987
156Dental crowding (HP:0000678)1.56527579
157Spastic paraplegia (HP:0001258)1.55514153
158Status epilepticus (HP:0002133)1.55510925
159Gastroesophageal reflux (HP:0002020)1.55206616
160Generalized tonic-clonic seizures (HP:0002069)1.55025730
161Hypothermia (HP:0002045)1.54688707
162Deep venous thrombosis (HP:0002625)1.52788290
163Neuroendocrine neoplasm (HP:0100634)1.51166676
164Short foot (HP:0001773)1.51052930
165Widely spaced teeth (HP:0000687)1.49958298
166Aplasia/Hypoplasia of the lens (HP:0008063)1.49944400
167Heterochromia iridis (HP:0001100)1.49080941
168Neoplasm of the rectum (HP:0100743)1.48794050
169Myelomeningocele (HP:0002475)1.47583612

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K23.64245747
2MAP3K43.54930131
3MAP2K72.93307545
4MARK12.91167375
5ERBB32.90627718
6EPHA42.77887817
7PNCK2.70662655
8FGFR22.57343645
9PLK22.52340463
10BCR2.47967466
11DAPK22.47566241
12CASK2.34351115
13BMPR1B2.14808731
14OBSCN2.10319562
15PHKG22.05968164
16PHKG12.05968164
17TAOK31.92856668
18MINK11.91777969
19MAP2K41.87636829
20NTRK21.87076576
21YES11.83921558
22PINK11.83126798
23DYRK21.72326947
24KSR11.68652716
25BCKDK1.68284416
26GRK11.67575150
27NUAK11.66114463
28TRIM281.64224782
29PAK61.63088780
30ADRBK21.56755197
31MAPKAPK31.56286455
32MAPK131.53693013
33PLK31.51952781
34PRPF4B1.49380733
35AKT31.46537864
36OXSR11.43280753
37FLT31.40714524
38ZAK1.39073976
39DAPK11.38186235
40WNK41.36767655
41STK38L1.31785266
42NTRK31.28711401
43NEK11.26290588
44ERBB41.22350754
45SGK21.19588160
46CSNK1G31.18555810
47CSNK1A1L1.18151203
48CSNK1G21.15314796
49CDK191.14851542
50FGFR11.13209078
51MAP3K91.11937600
52UHMK11.09274256
53FRK1.08749363
54STK391.01237837
55CDK81.01181267
56EEF2K0.99564078
57SGK2230.98850240
58SGK4940.98850240
59LMTK20.97951127
60TSSK60.96519144
61SIK30.91608969
62MAP3K120.90731751
63LATS20.85646573
64SGK30.85060449
65INSRR0.84869360
66CAMK1G0.84578942
67MAPKAPK50.84539553
68PAK30.84046705
69CSNK1G10.81126948
70LIMK10.80284651
71MYLK0.79155875
72ROCK20.76512573
73PASK0.76308294
74PRKD30.75884647
75CDK50.75323541
76SIK20.73418750
77CDK180.73231467
78LATS10.72712949
79EPHA30.72477202
80CDK140.72130708
81NEK60.70800770
82EPHB20.70178153
83CAMK2B0.69732794
84GRK50.68660468
85RPS6KB10.67549199
86RET0.67410630
87VRK10.66487839
88CDK150.63626099
89CAMK2D0.63128892
90PDGFRA0.62711682
91TYRO30.60654072
92WNK30.60521035
93PRKCG0.59620256
94TIE10.59287090
95BRSK20.59255895
96PRKAA10.58148264
97CAMK2A0.57823378
98CDC70.57344561
99MKNK20.55801539
100CSNK1E0.55155912
101PRKCE0.54909641
102CCNB10.54573774
103TGFBR10.54371689
104RPS6KA40.54100700
105ROCK10.51999464
106CDK11A0.51124803
107BMPR20.50693542
108MAP3K70.50683946
109SRPK10.50048511
110KIT0.49966793
111MAP3K20.48763659
112PRKACA0.48683812
113NTRK10.46866165
114TNIK0.46752314
115DYRK1A0.46675861
116EIF2AK20.46645161
117MET0.46456949
118MELK0.46245703
119PRKG10.46016409
120ATM0.45594228
121MAPK100.45343786
122PRKCH0.45041985
123FER0.44884863
124MUSK0.44508056
125PIK3CA0.43686805
126MAP3K60.43425075
127MKNK10.42842069
128PKN10.42833588
129STK110.42764916
130MAP3K50.41673419
131PRKACB0.40044753
132GRK70.39138863
133KSR20.38879345
134CDK30.38696394
135SGK10.38399145
136CAMK2G0.38247039
137CDK60.36906023
138CDK10.36550449
139CAMKK20.36286498
140TRPM70.35996504
141PRKCB0.35577619
142ADRBK10.35240810
143CSNK1D0.34962307
144RPS6KA50.34755278
145PRKCA0.34497872
146FGR0.34482441
147STK30.33563706
148CSNK1A10.31921426

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.79358181
2Nicotine addiction_Homo sapiens_hsa050332.75532591
3Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.56412680
4Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.55539141
5Protein export_Homo sapiens_hsa030602.49212029
6Taste transduction_Homo sapiens_hsa047422.12629855
7Primary bile acid biosynthesis_Homo sapiens_hsa001202.08063883
8Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.04262799
9Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.01537111
10Dopaminergic synapse_Homo sapiens_hsa047282.00176143
11Nitrogen metabolism_Homo sapiens_hsa009101.96633076
12Butanoate metabolism_Homo sapiens_hsa006501.91488960
13Caffeine metabolism_Homo sapiens_hsa002321.90740499
14GABAergic synapse_Homo sapiens_hsa047271.84471881
15Synaptic vesicle cycle_Homo sapiens_hsa047211.83444824
16Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.80875697
17Axon guidance_Homo sapiens_hsa043601.73750823
18Serotonergic synapse_Homo sapiens_hsa047261.72932681
19Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.70910836
20Cardiac muscle contraction_Homo sapiens_hsa042601.68098162
21Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.68080477
22Amphetamine addiction_Homo sapiens_hsa050311.62851661
23Long-term potentiation_Homo sapiens_hsa047201.59502070
24Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.54323832
25Oxidative phosphorylation_Homo sapiens_hsa001901.54007601
26Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.53620120
27Parkinsons disease_Homo sapiens_hsa050121.52518998
28Colorectal cancer_Homo sapiens_hsa052101.50165919
29Circadian entrainment_Homo sapiens_hsa047131.48401637
30Olfactory transduction_Homo sapiens_hsa047401.47634890
312-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.47281369
32Endometrial cancer_Homo sapiens_hsa052131.46378112
33Arginine biosynthesis_Homo sapiens_hsa002201.45555762
34Glutamatergic synapse_Homo sapiens_hsa047241.40092363
35Long-term depression_Homo sapiens_hsa047301.34592985
36ErbB signaling pathway_Homo sapiens_hsa040121.33789793
37Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.30156138
38Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.28558562
39Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.27414177
40Hippo signaling pathway_Homo sapiens_hsa043901.25010322
41Morphine addiction_Homo sapiens_hsa050321.23149712
42Vibrio cholerae infection_Homo sapiens_hsa051101.21694073
43Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.21203240
44Circadian rhythm_Homo sapiens_hsa047101.21140689
45Cholinergic synapse_Homo sapiens_hsa047251.19523403
46Glioma_Homo sapiens_hsa052141.16484375
47Steroid hormone biosynthesis_Homo sapiens_hsa001401.14472936
48One carbon pool by folate_Homo sapiens_hsa006701.13748574
49Retinol metabolism_Homo sapiens_hsa008301.13436640
50Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.10985359
51Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.08797079
52Linoleic acid metabolism_Homo sapiens_hsa005911.08178677
53Fanconi anemia pathway_Homo sapiens_hsa034601.08126499
54Dilated cardiomyopathy_Homo sapiens_hsa054141.07216432
55Basal transcription factors_Homo sapiens_hsa030221.06917975
56Cocaine addiction_Homo sapiens_hsa050301.06011123
57Chemical carcinogenesis_Homo sapiens_hsa052041.03587649
58GnRH signaling pathway_Homo sapiens_hsa049120.98495731
59Tight junction_Homo sapiens_hsa045300.97068692
60Alzheimers disease_Homo sapiens_hsa050100.96051875
61Non-small cell lung cancer_Homo sapiens_hsa052230.95886975
62Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.95266125
63Wnt signaling pathway_Homo sapiens_hsa043100.91976006
64Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.91767845
65Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.90047669
66Alcoholism_Homo sapiens_hsa050340.88906667
67Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.88618863
68Melanogenesis_Homo sapiens_hsa049160.87243781
69Fatty acid elongation_Homo sapiens_hsa000620.86945209
70Calcium signaling pathway_Homo sapiens_hsa040200.86582385
71Pyruvate metabolism_Homo sapiens_hsa006200.86312254
72Salivary secretion_Homo sapiens_hsa049700.84535111
73Renin secretion_Homo sapiens_hsa049240.83996710
74Type II diabetes mellitus_Homo sapiens_hsa049300.83935002
75Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.82958289
76Biosynthesis of amino acids_Homo sapiens_hsa012300.81306993
77Gap junction_Homo sapiens_hsa045400.80809422
78Sulfur metabolism_Homo sapiens_hsa009200.80721763
79Renal cell carcinoma_Homo sapiens_hsa052110.80355627
80Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.79726823
81Tryptophan metabolism_Homo sapiens_hsa003800.78408654
82Insulin secretion_Homo sapiens_hsa049110.77822468
83Prostate cancer_Homo sapiens_hsa052150.77728314
84Oocyte meiosis_Homo sapiens_hsa041140.77706159
85Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.77521657
86Phototransduction_Homo sapiens_hsa047440.77412964
87Regulation of autophagy_Homo sapiens_hsa041400.76609641
88Maturity onset diabetes of the young_Homo sapiens_hsa049500.76460790
89Pentose and glucuronate interconversions_Homo sapiens_hsa000400.76450111
90Fatty acid degradation_Homo sapiens_hsa000710.75737549
91Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.74510102
92Oxytocin signaling pathway_Homo sapiens_hsa049210.73635708
93Huntingtons disease_Homo sapiens_hsa050160.73440703
94alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.72992176
95Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.72988999
96Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.72703286
97Basal cell carcinoma_Homo sapiens_hsa052170.72648797
98Selenocompound metabolism_Homo sapiens_hsa004500.72463008
99Estrogen signaling pathway_Homo sapiens_hsa049150.71812449
100Melanoma_Homo sapiens_hsa052180.71334772
101Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.70996484
102Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.70735426
103Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.70391785
104Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.70095055
105Non-homologous end-joining_Homo sapiens_hsa034500.69800545
106Cysteine and methionine metabolism_Homo sapiens_hsa002700.69036558
107Ether lipid metabolism_Homo sapiens_hsa005650.69032893
108Propanoate metabolism_Homo sapiens_hsa006400.68056814
109beta-Alanine metabolism_Homo sapiens_hsa004100.68046419
110Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.67762288
111Glucagon signaling pathway_Homo sapiens_hsa049220.66725841
112Aldosterone synthesis and secretion_Homo sapiens_hsa049250.66468568
113Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.63761508
114TGF-beta signaling pathway_Homo sapiens_hsa043500.62958481
115Metabolic pathways_Homo sapiens_hsa011000.62789999
116mRNA surveillance pathway_Homo sapiens_hsa030150.62603920
117Collecting duct acid secretion_Homo sapiens_hsa049660.61993551
118Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.61108404
119Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.60472485
120MicroRNAs in cancer_Homo sapiens_hsa052060.60252591
121Pancreatic cancer_Homo sapiens_hsa052120.59495800
122Tyrosine metabolism_Homo sapiens_hsa003500.58217316
123RNA degradation_Homo sapiens_hsa030180.57395790
124Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.56087145
125Cell cycle_Homo sapiens_hsa041100.55887089
126RNA polymerase_Homo sapiens_hsa030200.55525560
127Gastric acid secretion_Homo sapiens_hsa049710.54392255
128Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.53278381
129Starch and sucrose metabolism_Homo sapiens_hsa005000.52994866
130cAMP signaling pathway_Homo sapiens_hsa040240.52070844
131Neurotrophin signaling pathway_Homo sapiens_hsa047220.51487073
132Nucleotide excision repair_Homo sapiens_hsa034200.51479542
133Choline metabolism in cancer_Homo sapiens_hsa052310.51462415
134Glycerolipid metabolism_Homo sapiens_hsa005610.51446031
135Hedgehog signaling pathway_Homo sapiens_hsa043400.50197170
136Carbon metabolism_Homo sapiens_hsa012000.49385429
137Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.49059896
138Arginine and proline metabolism_Homo sapiens_hsa003300.48504421
139Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.48427282
140Purine metabolism_Homo sapiens_hsa002300.48173695
141Steroid biosynthesis_Homo sapiens_hsa001000.48081822
142Ras signaling pathway_Homo sapiens_hsa040140.47960774
143ABC transporters_Homo sapiens_hsa020100.47417314
144Vitamin B6 metabolism_Homo sapiens_hsa007500.47072822
145Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.46502239
146Adherens junction_Homo sapiens_hsa045200.45233237
147Central carbon metabolism in cancer_Homo sapiens_hsa052300.44656791
148Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.44472216
149Peroxisome_Homo sapiens_hsa041460.43588938
150Thyroid hormone synthesis_Homo sapiens_hsa049180.42808629
151Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.39394711
152Fatty acid metabolism_Homo sapiens_hsa012120.38664395

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