BMS1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene likely encodes a ribosome assembly protein. A similar protein in yeast functions in 35S-rRNA processing, which includes a series of cleavage steps critical for formation of 40S ribosomes. Related pseudogenes exist on chromosomes 2, 9, 10, 15, 16, and 22. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)6.01919696
2nuclear pore organization (GO:0006999)5.89043580
3protein localization to kinetochore (GO:0034501)4.97507496
4pore complex assembly (GO:0046931)4.69979460
5mitotic nuclear envelope disassembly (GO:0007077)4.60900303
6DNA unwinding involved in DNA replication (GO:0006268)4.59490746
7establishment of integrated proviral latency (GO:0075713)4.57730910
8mitotic sister chromatid cohesion (GO:0007064)4.37327411
9nuclear envelope disassembly (GO:0051081)4.31896275
10membrane disassembly (GO:0030397)4.31896275
11mitotic chromosome condensation (GO:0007076)4.28769590
12protein localization to chromosome, centromeric region (GO:0071459)4.22489446
13mitotic metaphase plate congression (GO:0007080)4.14774704
14pre-miRNA processing (GO:0031054)4.13119501
15folic acid-containing compound biosynthetic process (GO:0009396)4.12308832
16telomere maintenance via semi-conservative replication (GO:0032201)4.03572843
17DNA replication-dependent nucleosome organization (GO:0034723)3.98781770
18DNA replication-dependent nucleosome assembly (GO:0006335)3.98781770
19double-strand break repair via nonhomologous end joining (GO:0006303)3.96323336
20non-recombinational repair (GO:0000726)3.96323336
21regulation of histone H3-K9 methylation (GO:0051570)3.94849715
22mitotic sister chromatid segregation (GO:0000070)3.92672298
23negative regulation of histone methylation (GO:0031061)3.91059847
24heterochromatin organization (GO:0070828)3.90660611
25sister chromatid segregation (GO:0000819)3.88032083
26regulation of spindle organization (GO:0090224)3.78958075
27DNA duplex unwinding (GO:0032508)3.77856136
28metaphase plate congression (GO:0051310)3.77668439
29DNA geometric change (GO:0032392)3.77470692
30regulation of gene silencing by RNA (GO:0060966)3.70401498
31regulation of posttranscriptional gene silencing (GO:0060147)3.70401498
32regulation of gene silencing by miRNA (GO:0060964)3.70401498
33IMP biosynthetic process (GO:0006188)3.69397124
34regulation of sister chromatid cohesion (GO:0007063)3.68881309
35mitotic recombination (GO:0006312)3.64142491
36telomere maintenance via recombination (GO:0000722)3.64072179
37DNA replication initiation (GO:0006270)3.62246187
38positive regulation of chromosome segregation (GO:0051984)3.61709735
39regulation of translational fidelity (GO:0006450)3.59904357
40regulation of mitotic spindle organization (GO:0060236)3.59858194
41positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.54493548
42positive regulation of mitotic sister chromatid separation (GO:1901970)3.54493548
43positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.54493548
44CENP-A containing nucleosome assembly (GO:0034080)3.53910417
45regulation of centriole replication (GO:0046599)3.53004177
46histone H2A monoubiquitination (GO:0035518)3.50717628
47regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.50512408
48establishment of viral latency (GO:0019043)3.43410500
49kinetochore organization (GO:0051383)3.42638249
50regulation of RNA export from nucleus (GO:0046831)3.39394133
51attachment of spindle microtubules to kinetochore (GO:0008608)3.36674210
52IMP metabolic process (GO:0046040)3.36582833
53nuclear envelope organization (GO:0006998)3.35734611
54establishment of chromosome localization (GO:0051303)3.34015212
55formation of translation preinitiation complex (GO:0001731)3.33081245
56tRNA aminoacylation for protein translation (GO:0006418)3.33039079
57nucleobase biosynthetic process (GO:0046112)3.32927684
58maturation of 5.8S rRNA (GO:0000460)3.32287356
59regulation of centrosome cycle (GO:0046605)3.31179943
60DNA strand elongation involved in DNA replication (GO:0006271)3.30485997
61protein localization to chromosome (GO:0034502)3.30236813
62DNA ligation (GO:0006266)3.29314380
63chromatin assembly (GO:0031497)3.29278644
64gene silencing by RNA (GO:0031047)3.29192687
65amino acid activation (GO:0043038)3.28213226
66tRNA aminoacylation (GO:0043039)3.28213226
67DNA topological change (GO:0006265)3.26087059
68dosage compensation (GO:0007549)3.24608162
69regulation of chromosome segregation (GO:0051983)3.20047979
70histone exchange (GO:0043486)3.19021568
71regulation of translational termination (GO:0006449)3.16719915
72chromatin assembly or disassembly (GO:0006333)3.15097044
73telomere maintenance via telomere lengthening (GO:0010833)3.14193539
74protein K6-linked ubiquitination (GO:0085020)3.13360291
75DNA strand elongation (GO:0022616)3.11688789
76DNA conformation change (GO:0071103)3.11680480
77DNA replication checkpoint (GO:0000076)3.10544051
78paraxial mesoderm development (GO:0048339)3.08856187
79regulation of mitotic metaphase/anaphase transition (GO:0030071)3.07627189
80mitochondrial RNA metabolic process (GO:0000959)3.07262747
81protein complex localization (GO:0031503)3.07189946
82negative regulation of mRNA processing (GO:0050686)3.06778894
83DNA double-strand break processing (GO:0000729)3.06572723
84negative regulation of chromosome segregation (GO:0051985)3.04001625
85regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.03695775
86spindle checkpoint (GO:0031577)3.01448146
87negative regulation of DNA repair (GO:0045738)3.01337049
88negative regulation of mRNA metabolic process (GO:1903312)3.00127487
89meiotic chromosome segregation (GO:0045132)2.99199199
90* ribosome assembly (GO:0042255)2.98556998
91spindle assembly checkpoint (GO:0071173)2.97613375
92regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.97045094
93nucleotide-excision repair, DNA gap filling (GO:0006297)2.96702066
94RNA stabilization (GO:0043489)2.96686490
95mRNA stabilization (GO:0048255)2.96686490
96telomere maintenance (GO:0000723)2.96400567
97negative regulation of mitotic sister chromatid separation (GO:2000816)2.96300488
98negative regulation of mitotic sister chromatid segregation (GO:0033048)2.96300488
99negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.96300488
100negative regulation of sister chromatid segregation (GO:0033046)2.96300488
101chromosome condensation (GO:0030261)2.95900684
102mitotic spindle assembly checkpoint (GO:0007094)2.95087825
103DNA replication-independent nucleosome organization (GO:0034724)2.94345910
104DNA replication-independent nucleosome assembly (GO:0006336)2.94345910
105mitotic spindle checkpoint (GO:0071174)2.94209395
106telomere organization (GO:0032200)2.93753133
107transcription from mitochondrial promoter (GO:0006390)2.92217858
108mRNA transport (GO:0051028)2.91770535
109negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.91545915
110chromatin remodeling at centromere (GO:0031055)2.91287547
111gene silencing (GO:0016458)2.90520500
112regulation of mitotic sister chromatid separation (GO:0010965)2.89775001
113regulation of mitotic sister chromatid segregation (GO:0033047)2.89775001
114regulation of sister chromatid segregation (GO:0033045)2.89775001
115translesion synthesis (GO:0019985)2.89473754
116RNA-dependent DNA replication (GO:0006278)2.89211637
117somatic hypermutation of immunoglobulin genes (GO:0016446)2.88978760
118somatic diversification of immune receptors via somatic mutation (GO:0002566)2.88978760
119regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.88267506
120purine nucleobase biosynthetic process (GO:0009113)2.87705373
121telomere maintenance via telomerase (GO:0007004)2.87641125
122anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.87114814
123spliceosomal tri-snRNP complex assembly (GO:0000244)2.86581142
124regulation of DNA endoreduplication (GO:0032875)2.86053452
125negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.85488118
126regulation of helicase activity (GO:0051095)2.84978093
127maturation of SSU-rRNA (GO:0030490)2.84775622
128ribosome biogenesis (GO:0042254)2.83570528
129chromosome segregation (GO:0007059)2.83102829
130ATP-dependent chromatin remodeling (GO:0043044)2.81063839
131regulation of centrosome duplication (GO:0010824)2.79203665

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.91425102
2FOXM1_23109430_ChIP-Seq_U2OS_Human5.49104528
3E2F4_17652178_ChIP-ChIP_JURKAT_Human3.98717335
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.69557754
5FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.40187976
6EGR1_19374776_ChIP-ChIP_THP-1_Human3.19785336
7EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.89926193
8MYC_19079543_ChIP-ChIP_MESCs_Mouse2.82640745
9* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.68646879
10MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.57102057
11AR_21909140_ChIP-Seq_LNCAP_Human2.54537129
12MYC_22102868_ChIP-Seq_BL_Human2.48339811
13* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.41524971
14E2F1_21310950_ChIP-Seq_MCF-7_Human2.33215334
15NELFA_20434984_ChIP-Seq_ESCs_Mouse2.24732822
16E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.09045195
17SALL1_21062744_ChIP-ChIP_HESCs_Human2.08530354
18NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.04058652
19MYC_18358816_ChIP-ChIP_MESCs_Mouse2.00391950
20* XRN2_22483619_ChIP-Seq_HELA_Human1.91971504
21NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.91816489
22MYCN_18555785_ChIP-Seq_MESCs_Mouse1.89712025
23MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.83001225
24EST1_17652178_ChIP-ChIP_JURKAT_Human1.72731422
25SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.70913567
26POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.70054954
27HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.62003246
28* ETS1_20019798_ChIP-Seq_JURKAT_Human1.61748654
29NANOG_18555785_ChIP-Seq_MESCs_Mouse1.57907454
30ELF1_17652178_ChIP-ChIP_JURKAT_Human1.57664895
31STAT3_1855785_ChIP-Seq_MESCs_Mouse1.55800655
32POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.53155678
33CREB1_15753290_ChIP-ChIP_HEK293T_Human1.52342739
34CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.50928592
35ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.49114173
36TP63_19390658_ChIP-ChIP_HaCaT_Human1.48191179
37* KDM5A_27292631_Chip-Seq_BREAST_Human1.47457903
38* VDR_23849224_ChIP-Seq_CD4+_Human1.46101846
39PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.45498236
40RBPJ_22232070_ChIP-Seq_NCS_Mouse1.44490195
41YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.44350697
42CIITA_25753668_ChIP-Seq_RAJI_Human1.42758284
43SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.41218350
44ZFX_18555785_ChIP-Seq_MESCs_Mouse1.40771566
45KLF4_18555785_ChIP-Seq_MESCs_Mouse1.38771784
46TTF2_22483619_ChIP-Seq_HELA_Human1.38761257
47* FOXP3_21729870_ChIP-Seq_TREG_Human1.38507832
48ESR1_15608294_ChIP-ChIP_MCF-7_Human1.37348285
49E2F1_18555785_ChIP-Seq_MESCs_Mouse1.35941087
50GABP_19822575_ChIP-Seq_HepG2_Human1.35432867
51SRF_21415370_ChIP-Seq_HL-1_Mouse1.31191686
52MYC_18940864_ChIP-ChIP_HL60_Human1.30148619
53DCP1A_22483619_ChIP-Seq_HELA_Human1.29911429
54GABP_17652178_ChIP-ChIP_JURKAT_Human1.26754994
55KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.26628817
56FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.24487727
57CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.23675761
58* JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.23202618
59* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.22579052
60TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.22233667
61* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.22058381
62ELK1_19687146_ChIP-ChIP_HELA_Human1.21145550
63CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.18051912
64* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.17877098
65TFEB_21752829_ChIP-Seq_HELA_Human1.17493283
66TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.17345294
67VDR_21846776_ChIP-Seq_THP-1_Human1.17193022
68HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.16219463
69NANOG_21062744_ChIP-ChIP_HESCs_Human1.15988833
70SOX17_20123909_ChIP-Seq_XEN_Mouse1.15649748
71NOTCH1_21737748_ChIP-Seq_TLL_Human1.15602331
72KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.15306654
73KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.15306654
74KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.15306654
75ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.14689469
76TCF3_18692474_ChIP-Seq_MEFs_Mouse1.11619921
77* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.11305403
78E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.11044905
79ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.11010397
80PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.10697240
81SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.10096264
82ERG_20887958_ChIP-Seq_HPC-7_Mouse1.09283291
83SOX2_18555785_ChIP-Seq_MESCs_Mouse1.07790639
84YY1_21170310_ChIP-Seq_MESCs_Mouse1.07621983
85PADI4_21655091_ChIP-ChIP_MCF-7_Human1.07512479
86POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.06360228
87MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.04575893
88NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.00649336
89STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.00219232
90CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.99011400
91HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.97877548
92KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.97599179
93THAP11_20581084_ChIP-Seq_MESCs_Mouse0.97563597
94SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.96281400
95SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.95900318
96ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.95357479
97TCF7_22412390_ChIP-Seq_EML_Mouse0.95104310
98* CHD1_26751641_Chip-Seq_LNCaP_Human0.94364577
99HOXB4_20404135_ChIP-ChIP_EML_Mouse0.93468917
100CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.93216662
101FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.91941068
102TCF3_18692474_ChIP-Seq_MESCs_Mouse0.91584534
103DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.88819404
104ATF3_27146783_Chip-Seq_COLON_Human0.87988225
105NANOG_16153702_ChIP-ChIP_HESCs_Human0.87409830
106* UTX_26944678_Chip-Seq_JUKART_Human0.87366143
107KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.87143642
108FUS_26573619_Chip-Seq_HEK293_Human0.84439789
109KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.84068549
110NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.83736037
111CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.83641738
112KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.83487931
113EWS_26573619_Chip-Seq_HEK293_Human0.83038398
114BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.82016681
115HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.81655155
116TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.81612129
117MYB_26560356_Chip-Seq_TH1_Human0.81510120
118PKCTHETA_26484144_Chip-Seq_BREAST_Human0.81345193
119HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.81113654
120HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.81025871
121PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.80991201
122KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.79815224
123GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.76188840
124ELK1_22589737_ChIP-Seq_MCF10A_Human0.74848256
125TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.72169514
126* ELF5_23300383_ChIP-Seq_T47D_Human0.72056535
127TBX5_21415370_ChIP-Seq_HL-1_Mouse0.71405727
128CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.71257194
129NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.70212676

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability4.00888881
2MP0003693_abnormal_embryo_hatching3.85925368
3MP0003111_abnormal_nucleus_morphology3.81143998
4MP0004957_abnormal_blastocyst_morpholog3.54724278
5MP0003077_abnormal_cell_cycle3.41931650
6MP0003705_abnormal_hypodermis_morpholog3.07843620
7MP0010352_gastrointestinal_tract_polyps3.06065767
8MP0008057_abnormal_DNA_replication3.04325555
9MP0008877_abnormal_DNA_methylation2.76895908
10MP0009697_abnormal_copulation2.64659414
11MP0001730_embryonic_growth_arrest2.55128345
12MP0010307_abnormal_tumor_latency2.34921828
13MP0003123_paternal_imprinting2.34715512
14MP0008058_abnormal_DNA_repair2.25097084
15MP0008007_abnormal_cellular_replicative2.23525003
16MP0000350_abnormal_cell_proliferation2.23331537
17MP0005076_abnormal_cell_differentiation2.14437462
18MP0001672_abnormal_embryogenesis/_devel1.99413950
19MP0005380_embryogenesis_phenotype1.99413950
20MP0008932_abnormal_embryonic_tissue1.92384128
21MP0002396_abnormal_hematopoietic_system1.87945378
22MP0002084_abnormal_developmental_patter1.84935576
23MP0004197_abnormal_fetal_growth/weight/1.83454127
24MP0001697_abnormal_embryo_size1.82804117
25MP0003121_genomic_imprinting1.82314609
26MP0003984_embryonic_growth_retardation1.81082371
27MP0002088_abnormal_embryonic_growth/wei1.77914427
28MP0002085_abnormal_embryonic_tissue1.76140939
29MP0002086_abnormal_extraembryonic_tissu1.73639007
30MP0003890_abnormal_embryonic-extraembry1.64266950
31MP0002080_prenatal_lethality1.60000422
32MP0004808_abnormal_hematopoietic_stem1.54531281
33MP0003566_abnormal_cell_adhesion1.53179558
34MP0010030_abnormal_orbit_morphology1.48709943
35MP0003567_abnormal_fetal_cardiomyocyte1.45686092
36MP0003315_abnormal_perineum_morphology1.43698695
37MP0003786_premature_aging1.39218732
38MP0001661_extended_life_span1.34319431
39MP0006035_abnormal_mitochondrial_morpho1.34293951
40MP0005023_abnormal_wound_healing1.32662745
41MP0001915_intracranial_hemorrhage1.29110994
42MP0009053_abnormal_anal_canal1.28173373
43MP0000733_abnormal_muscle_development1.26877721
44MP0002210_abnormal_sex_determination1.23016879
45MP0000313_abnormal_cell_death1.22027311
46MP0002019_abnormal_tumor_incidence1.21572516
47MP0003718_maternal_effect1.20627962
48MP0000537_abnormal_urethra_morphology1.15364000
49MP0001293_anophthalmia1.13268171
50MP0000490_abnormal_crypts_of1.11717322
51MP0010234_abnormal_vibrissa_follicle1.07112320
52MP0001929_abnormal_gametogenesis1.06069737
53MP0009672_abnormal_birth_weight1.04529021
54MP0000428_abnormal_craniofacial_morphol1.04392796
55MP0004272_abnormal_basement_membrane1.02537478
56MP0001849_ear_inflammation1.02282040
57MP0001145_abnormal_male_reproductive1.01735795
58MP0004264_abnormal_extraembryonic_tissu1.01486953
59MP0006036_abnormal_mitochondrial_physio1.00672853
60MP0003937_abnormal_limbs/digits/tail_de1.00558931
61MP0000703_abnormal_thymus_morphology1.00557746
62MP0009703_decreased_birth_body0.99392971
63MP0003119_abnormal_digestive_system0.99014892
64MP0004233_abnormal_muscle_weight0.97009622
65MP0003806_abnormal_nucleotide_metabolis0.96566724
66MP0005501_abnormal_skin_physiology0.96142669
67MP0000653_abnormal_sex_gland0.93494032
68MP0005623_abnormal_meninges_morphology0.92603223
69MP0002877_abnormal_melanocyte_morpholog0.91109168
70MP0003763_abnormal_thymus_physiology0.90181901
71MP0005397_hematopoietic_system_phenotyp0.90165646
72MP0001545_abnormal_hematopoietic_system0.90165646
73MP0002925_abnormal_cardiovascular_devel0.89943616
74MP0006292_abnormal_olfactory_placode0.89555957
75MP0002160_abnormal_reproductive_system0.89340745
76MP0006054_spinal_hemorrhage0.89139701
77MP0004185_abnormal_adipocyte_glucose0.88267346
78MP0009278_abnormal_bone_marrow0.88239660
79MP0002233_abnormal_nose_morphology0.87667939
80MP0003385_abnormal_body_wall0.87459739
81MP0008438_abnormal_cutaneous_collagen0.87003854
82MP0003950_abnormal_plasma_membrane0.86667224
83MP0002653_abnormal_ependyma_morphology0.86530962
84MP0002796_impaired_skin_barrier0.85985498
85MP0005621_abnormal_cell_physiology0.85835228
86MP0002938_white_spotting0.85508244
87MP0002111_abnormal_tail_morphology0.84648185
88MP0002092_abnormal_eye_morphology0.83848077
89MP0003300_gastrointestinal_ulcer0.83463351
90MP0001727_abnormal_embryo_implantation0.83009115
91MP0000432_abnormal_head_morphology0.82908959
92MP0001299_abnormal_eye_distance/0.82481822
93MP0005384_cellular_phenotype0.82333032
94MP0002697_abnormal_eye_size0.82074623
95MP0000627_abnormal_mammary_gland0.82015555
96MP0002269_muscular_atrophy0.81475179
97MP0003787_abnormal_imprinting0.79828354
98MP0003755_abnormal_palate_morphology0.79304167
99MP0000647_abnormal_sebaceous_gland0.78017017
100MP0003115_abnormal_respiratory_system0.77464990
101MP0002398_abnormal_bone_marrow0.77273873
102MP0001119_abnormal_female_reproductive0.76554241
103MP0001346_abnormal_lacrimal_gland0.76485030
104MP0000749_muscle_degeneration0.76401291
105MP0002722_abnormal_immune_system0.75095770
106MP0003943_abnormal_hepatobiliary_system0.74638187
107MP0005395_other_phenotype0.74512819
108MP0003935_abnormal_craniofacial_develop0.74213305
109MP0000569_abnormal_digit_pigmentation0.73268123
110MP0000266_abnormal_heart_morphology0.72998962
111MP0001881_abnormal_mammary_gland0.72560198
112MP0005187_abnormal_penis_morphology0.72547246
113MP0003221_abnormal_cardiomyocyte_apopto0.72108686
114MP0010678_abnormal_skin_adnexa0.69393539
115MP0002060_abnormal_skin_morphology0.69224527
116MP0000579_abnormal_nail_morphology0.69147776
117MP0000689_abnormal_spleen_morphology0.68317225
118MP0003091_abnormal_cell_migration0.67987574
119MP0010630_abnormal_cardiac_muscle0.67898541
120MP0003186_abnormal_redox_activity0.67231360
121MP0003941_abnormal_skin_development0.66526595
122MP0006072_abnormal_retinal_apoptosis0.66234937
123MP0003699_abnormal_female_reproductive0.66230114
124MP0001286_abnormal_eye_development0.65251481
125MP0000358_abnormal_cell_content/0.63099092
126MP0002009_preneoplasia0.61209240
127MP0001529_abnormal_vocalization0.60490535
128MP0008770_decreased_survivor_rate0.60158726
129MP0000477_abnormal_intestine_morphology0.59599144
130MP0002932_abnormal_joint_morphology0.58975212
131MP0003453_abnormal_keratinocyte_physiol0.58880343
132MP0004133_heterotaxia0.58271216
133MP0009333_abnormal_splenocyte_physiolog0.57785808

Predicted human phenotypes

RankGene SetZ-score
1Ependymoma (HP:0002888)3.71580379
2Selective tooth agenesis (HP:0001592)3.64411288
3Medulloblastoma (HP:0002885)3.23612328
4Volvulus (HP:0002580)3.07518845
5Chromsome breakage (HP:0040012)3.03732813
6Nephroblastoma (Wilms tumor) (HP:0002667)3.00547730
7Deviation of the thumb (HP:0009603)2.97715526
8Increased nuchal translucency (HP:0010880)2.96731553
9Proximal placement of thumb (HP:0009623)2.92120336
10Rhabdomyosarcoma (HP:0002859)2.91655097
11Embryonal renal neoplasm (HP:0011794)2.83213169
12Colon cancer (HP:0003003)2.83094424
13Abnormality of the labia minora (HP:0012880)2.82738234
14Abnormality of the astrocytes (HP:0100707)2.79632710
15Astrocytoma (HP:0009592)2.79632710
16Impulsivity (HP:0100710)2.79576811
17Basal cell carcinoma (HP:0002671)2.75268497
18Multiple enchondromatosis (HP:0005701)2.69703563
19Birth length less than 3rd percentile (HP:0003561)2.69358570
20Abnormality of chromosome stability (HP:0003220)2.60933057
21Agnosia (HP:0010524)2.55820160
22Short 4th metacarpal (HP:0010044)2.54693712
23Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.54693712
24Prominent nose (HP:0000448)2.54431054
25Chromosomal breakage induced by crosslinking agents (HP:0003221)2.50584932
26Neoplasm of the oral cavity (HP:0100649)2.48000757
27Progressive muscle weakness (HP:0003323)2.46620349
28Abnormality of the duodenum (HP:0002246)2.46311908
29Abnormality of the fingertips (HP:0001211)2.44477613
30Abnormality of methionine metabolism (HP:0010901)2.44333375
31Patellar aplasia (HP:0006443)2.43273394
32High pitched voice (HP:0001620)2.43146739
33Abnormal number of incisors (HP:0011064)2.40310378
34Neoplasm of striated muscle (HP:0009728)2.37908514
35Microvesicular hepatic steatosis (HP:0001414)2.37560134
36Progressive external ophthalmoplegia (HP:0000590)2.34238252
37Abnormal lung lobation (HP:0002101)2.31125508
38Abnormality of glycolysis (HP:0004366)2.30198078
39Ectopic kidney (HP:0000086)2.28524831
40Cutaneous melanoma (HP:0012056)2.28442032
41Malignant gastrointestinal tract tumors (HP:0006749)2.27425006
42Gastrointestinal carcinoma (HP:0002672)2.27425006
43Long eyelashes (HP:0000527)2.25756888
44Reduced antithrombin III activity (HP:0001976)2.23762022
45Glioma (HP:0009733)2.23696101
46Aplasia/Hypoplasia of the patella (HP:0006498)2.23575036
47Sandal gap (HP:0001852)2.23278310
48Biliary tract neoplasm (HP:0100574)2.22166023
49Meckel diverticulum (HP:0002245)2.21630476
50Degeneration of anterior horn cells (HP:0002398)2.18190915
51Abnormality of the anterior horn cell (HP:0006802)2.18190915
52Supernumerary spleens (HP:0009799)2.13906987
53Ankle contracture (HP:0006466)2.13702231
54Squamous cell carcinoma (HP:0002860)2.11873421
55Missing ribs (HP:0000921)2.11433790
56Facial hemangioma (HP:0000329)2.10112406
57Myelodysplasia (HP:0002863)2.09667192
58Abnormality of the ileum (HP:0001549)2.09409377
59Horseshoe kidney (HP:0000085)2.06524296
60Cafe-au-lait spot (HP:0000957)2.05696219
61Breast hypoplasia (HP:0003187)2.05594600
62Increased serum pyruvate (HP:0003542)2.03610524
63Choanal atresia (HP:0000453)2.02342762
64Secondary amenorrhea (HP:0000869)2.02230905
65Aplasia/Hypoplasia of the uvula (HP:0010293)2.02109303
66High anterior hairline (HP:0009890)2.01276551
67Reticulocytopenia (HP:0001896)2.00500425
68Duodenal stenosis (HP:0100867)1.99863739
69Small intestinal stenosis (HP:0012848)1.99863739
70Abdominal situs inversus (HP:0003363)1.99460907
71Abnormality of abdominal situs (HP:0011620)1.99460907
72Shallow orbits (HP:0000586)1.99450006
73Atresia of the external auditory canal (HP:0000413)1.98456463
74Facial cleft (HP:0002006)1.98247947
75Sloping forehead (HP:0000340)1.96762628
76Absent radius (HP:0003974)1.93926809
77Clubbing of toes (HP:0100760)1.93912306
78Overlapping toe (HP:0001845)1.93610716
79Hyperacusis (HP:0010780)1.93232408
80Pancreatic islet-cell hyperplasia (HP:0004510)1.92787771
81Neoplasm of the pancreas (HP:0002894)1.92655943
82Heterotopia (HP:0002282)1.92647633
83Deep philtrum (HP:0002002)1.91237721
84Amaurosis fugax (HP:0100576)1.90604853
85Shoulder girdle muscle weakness (HP:0003547)1.89895426
86Abnormality of the preputium (HP:0100587)1.88707900
87Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.88366543
88Increased density of long bones (HP:0006392)1.87953602
89Postnatal microcephaly (HP:0005484)1.87264472
90Type I transferrin isoform profile (HP:0003642)1.87186821
91Absent thumb (HP:0009777)1.87093451
92Abnormality of the 4th metacarpal (HP:0010012)1.86145665
93Neoplasm of the colon (HP:0100273)1.85374584
94Aplasia/hypoplasia of the humerus (HP:0006507)1.84138568
95Abnormality of the calcaneus (HP:0008364)1.83211923
96Renal duplication (HP:0000075)1.83113955
97Neoplasm of the adrenal cortex (HP:0100641)1.82946484
98Short humerus (HP:0005792)1.81142422
99Aplasia/Hypoplasia of the sternum (HP:0006714)1.81125766
100Abnormality of the carotid arteries (HP:0005344)1.81051134
101Protrusio acetabuli (HP:0003179)1.80388014
102Skin tags (HP:0010609)1.80239835
103Cerebral aneurysm (HP:0004944)1.79280800
104Rib fusion (HP:0000902)1.79276008
105Aplasia involving forearm bones (HP:0009822)1.77860607
106Absent forearm bone (HP:0003953)1.77860607
107Pelvic girdle muscle weakness (HP:0003749)1.77721584
108Supernumerary ribs (HP:0005815)1.77003955
109Trigonocephaly (HP:0000243)1.76949435
11011 pairs of ribs (HP:0000878)1.76530071
111Acute myeloid leukemia (HP:0004808)1.76515482
112Oral leukoplakia (HP:0002745)1.76406650
113Low anterior hairline (HP:0000294)1.76087141
114Urethral obstruction (HP:0000796)1.76067029
115Premature ovarian failure (HP:0008209)1.75541239
116Ulnar bowing (HP:0003031)1.73640545
117Homocystinuria (HP:0002156)1.73473162
118Abnormality of homocysteine metabolism (HP:0010919)1.73473162
119Pseudobulbar signs (HP:0002200)1.73369397
120Abnormality of the pons (HP:0007361)1.72265257
121Cutis marmorata (HP:0000965)1.71043307
122Renovascular hypertension (HP:0100817)1.71034243
123Abnormal protein glycosylation (HP:0012346)1.70774093
124Abnormal glycosylation (HP:0012345)1.70774093
125Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.70774093
126Abnormal protein N-linked glycosylation (HP:0012347)1.70774093
127Blepharitis (HP:0000498)1.70750912
128Duplicated collecting system (HP:0000081)1.70528096
129Cortical dysplasia (HP:0002539)1.70301778
130Triphalangeal thumb (HP:0001199)1.70022630
131Broad palm (HP:0001169)1.69966289
132Rectal prolapse (HP:0002035)1.69245954
133Spastic diplegia (HP:0001264)1.69137647
134Increased hepatocellular lipid droplets (HP:0006565)1.63405508
135Lipid accumulation in hepatocytes (HP:0006561)1.61774718
136Hypoplasia of the pons (HP:0012110)1.61713182
137Arteriovenous malformation (HP:0100026)1.60760204
138Abnormality of aspartate family amino acid metabolism (HP:0010899)1.60139057
139Neoplasm of the adrenal gland (HP:0100631)1.59545611
140Abnormality of DNA repair (HP:0003254)1.59066845
141Increased serum lactate (HP:0002151)1.57919304
142Prominent metopic ridge (HP:0005487)1.57096823
143Microglossia (HP:0000171)1.56561721
144Poikiloderma (HP:0001029)1.55989427
145Neuroblastic tumors (HP:0004376)1.55005890
146Peripheral primitive neuroectodermal neoplasm (HP:0030067)1.55005890
147Neuroblastoma (HP:0003006)1.55005890
148Primitive neuroectodermal tumor (HP:0030065)1.55005890
149Megaloblastic anemia (HP:0001889)1.54941266
150Abnormality of the umbilical cord (HP:0010881)1.54672679
151Entropion (HP:0000621)1.54031050
152Capillary hemangiomas (HP:0005306)1.53976847

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK124.49507676
2CDC74.29540292
3NEK23.09118843
4EEF2K2.91473481
5PBK2.78093645
6TTK2.73298535
7WEE12.71682746
8PKN22.31468821
9BUB12.25101808
10STK102.21086007
11PASK2.10793256
12MAP3K102.06611573
13NEK12.03271958
14TSSK61.91657241
15PLK41.91567186
16LATS11.81052182
17CDK41.78471217
18VRK21.77471876
19RPS6KB21.76066928
20TAF11.68679955
21PLK11.64857092
22ACVR1B1.63094118
23BRD41.62039898
24SRPK11.53610088
25ATR1.53147591
26MAP3K81.50273567
27CHEK11.47752637
28AURKB1.46669966
29CHEK21.45840370
30TRIB31.44693909
31CDK71.42597820
32CDK61.42018674
33ALK1.38922100
34MST1R1.36625115
35STK31.33214664
36EIF2AK11.32931310
37SMG11.32617264
38TTN1.32346175
39PAK41.27360417
40TGFBR11.26825672
41PLK31.21462532
42MTOR1.21003826
43TRIM281.19845301
44EIF2AK21.19820141
45MKNK11.18308420
46EPHA21.17486495
47SCYL21.17281193
48MELK1.15740306
49RPS6KA41.14919668
50LATS21.13047177
51ATM1.11215371
52NME11.09594338
53LRRK21.07768250
54BRSK21.04139180
55STK161.00398495
56FLT31.00059871
57PIM10.99433901
58MKNK20.99090651
59TNIK0.97998499
60CDK20.97723112
61ERBB40.97262089
62STK40.97135695
63NUAK10.96059764
64PDK30.95954808
65PDK40.95954808
66VRK10.94709800
67PDGFRA0.83094510
68CDK80.79090133
69PNCK0.78805356
70CCNB10.78636545
71BCR0.77572261
72BMX0.76820534
73MAP4K10.76019208
74PAK20.73340971
75MET0.73089988
76AURKA0.72629546
77ICK0.70482795
78TESK20.70007908
79CLK10.69100063
80CDK10.69086242
81FGFR10.67101383
82STK38L0.66032421
83MAP2K30.65057240
84PTK60.63233535
85CDK90.59078104
86DYRK30.58043276
87CSNK1E0.56752375
88CSNK1D0.56445350
89RIPK10.56394067
90CAMK1D0.56243220
91DMPK0.52810477
92MAP3K120.52124521
93CDK30.50972450
94CSNK1G10.50472038
95CSNK2A20.50397752
96BMPR1B0.50071290
97ERBB30.49412618
98PRKDC0.48960808
99ZAK0.47641736
100TLK10.46869003
101CSNK1A1L0.44525014
102GRK60.43986986
103PLK20.43274487
104AKT20.41609818
105MAPK140.40698103
106TYK20.40662639
107BRSK10.40538097
108PAK10.40405360
109JAK30.40371802
110PDGFRB0.39777284
111MST40.38972717
112CAMK1G0.38699477
113CSNK1G30.38493487
114EIF2AK30.36544184
115WNK30.36355855
116MAP3K60.36341340
117AKT10.35798174
118MARK30.35747357
119PINK10.35650055
120MAP4K20.35399379
121MAPK10.34021659
122RAF10.33604544
123CHUK0.32530713
124DAPK10.32504237
125MAP2K70.32320162
126KSR10.31534000
127GSK3B0.30070132
128TAOK10.29828500
129CSNK2A10.29523795
130TESK10.28225733
131PDK20.28015777
132BRAF0.27442233
133RPS6KB10.27095324
134PRKCI0.25810911
135NME20.25228820
136MAPKAPK30.24787555

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.78509256
2Mismatch repair_Homo sapiens_hsa034303.42573170
3* Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.40713550
4RNA transport_Homo sapiens_hsa030133.35694801
5One carbon pool by folate_Homo sapiens_hsa006703.04269942
6Cell cycle_Homo sapiens_hsa041102.97424647
7Spliceosome_Homo sapiens_hsa030402.92155627
8Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.58887387
9Base excision repair_Homo sapiens_hsa034102.30082355
10Homologous recombination_Homo sapiens_hsa034402.28667611
11mRNA surveillance pathway_Homo sapiens_hsa030152.26766293
12Nucleotide excision repair_Homo sapiens_hsa034202.25994283
13Non-homologous end-joining_Homo sapiens_hsa034502.19140548
14Fanconi anemia pathway_Homo sapiens_hsa034602.09384850
15RNA degradation_Homo sapiens_hsa030181.90611549
16Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.78762069
17p53 signaling pathway_Homo sapiens_hsa041151.74065402
18Basal transcription factors_Homo sapiens_hsa030221.63211570
19RNA polymerase_Homo sapiens_hsa030201.60520389
20Protein export_Homo sapiens_hsa030601.49155835
21Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.46340544
22Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.45311130
23Viral carcinogenesis_Homo sapiens_hsa052031.43380448
24MicroRNAs in cancer_Homo sapiens_hsa052061.42423297
25Ribosome_Homo sapiens_hsa030101.42417428
26Systemic lupus erythematosus_Homo sapiens_hsa053221.42113854
27Pyrimidine metabolism_Homo sapiens_hsa002401.34841951
28Pyruvate metabolism_Homo sapiens_hsa006201.32972791
29Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.24256367
30Antigen processing and presentation_Homo sapiens_hsa046121.23911827
31Selenocompound metabolism_Homo sapiens_hsa004501.23143953
32Propanoate metabolism_Homo sapiens_hsa006401.22275954
33Adherens junction_Homo sapiens_hsa045201.19052969
34Epstein-Barr virus infection_Homo sapiens_hsa051691.18171364
35Small cell lung cancer_Homo sapiens_hsa052221.16207214
36HTLV-I infection_Homo sapiens_hsa051661.16188215
37Vitamin B6 metabolism_Homo sapiens_hsa007501.15892489
38Oocyte meiosis_Homo sapiens_hsa041141.14080154
39Herpes simplex infection_Homo sapiens_hsa051681.09900514
40Lysine degradation_Homo sapiens_hsa003101.06945902
41Biosynthesis of amino acids_Homo sapiens_hsa012301.06888094
42Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.05843303
43Thyroid cancer_Homo sapiens_hsa052161.02109980
44Chronic myeloid leukemia_Homo sapiens_hsa052201.01781167
45Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.99895989
46mTOR signaling pathway_Homo sapiens_hsa041500.98666403
47TGF-beta signaling pathway_Homo sapiens_hsa043500.94426531
48Colorectal cancer_Homo sapiens_hsa052100.92655830
49Proteasome_Homo sapiens_hsa030500.92126058
50Hippo signaling pathway_Homo sapiens_hsa043900.92029445
51Central carbon metabolism in cancer_Homo sapiens_hsa052300.89915527
52Steroid biosynthesis_Homo sapiens_hsa001000.87823183
53Cysteine and methionine metabolism_Homo sapiens_hsa002700.85339665
54Basal cell carcinoma_Homo sapiens_hsa052170.84735167
55Transcriptional misregulation in cancer_Homo sapiens_hsa052020.83771832
56Notch signaling pathway_Homo sapiens_hsa043300.83462828
57Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.81490645
58Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.81127199
59Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.78371358
60Viral myocarditis_Homo sapiens_hsa054160.78168831
61Proteoglycans in cancer_Homo sapiens_hsa052050.75090644
62Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.75085576
63N-Glycan biosynthesis_Homo sapiens_hsa005100.74924890
64Cyanoamino acid metabolism_Homo sapiens_hsa004600.73671853
65Pancreatic cancer_Homo sapiens_hsa052120.72752260
66Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.72356699
67Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.69087844
68Glutathione metabolism_Homo sapiens_hsa004800.67666187
69Pentose phosphate pathway_Homo sapiens_hsa000300.66225759
70Fatty acid elongation_Homo sapiens_hsa000620.66070876
71HIF-1 signaling pathway_Homo sapiens_hsa040660.65411703
72Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.64171956
73Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.64033877
74Thyroid hormone signaling pathway_Homo sapiens_hsa049190.63771419
75Folate biosynthesis_Homo sapiens_hsa007900.63750707
76Bladder cancer_Homo sapiens_hsa052190.61370907
77Apoptosis_Homo sapiens_hsa042100.59443682
78Prostate cancer_Homo sapiens_hsa052150.59434228
79Acute myeloid leukemia_Homo sapiens_hsa052210.59352815
80Pathways in cancer_Homo sapiens_hsa052000.56445051
81Purine metabolism_Homo sapiens_hsa002300.56118126
82Legionellosis_Homo sapiens_hsa051340.55472377
83Hepatitis B_Homo sapiens_hsa051610.55202794
84Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.52733457
85Focal adhesion_Homo sapiens_hsa045100.51750987
86Non-small cell lung cancer_Homo sapiens_hsa052230.51366731
87NF-kappa B signaling pathway_Homo sapiens_hsa040640.50706529
88Endometrial cancer_Homo sapiens_hsa052130.49124238
89Carbon metabolism_Homo sapiens_hsa012000.49092572
90Measles_Homo sapiens_hsa051620.48946122
91Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.47230403
92Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.47147283
93Shigellosis_Homo sapiens_hsa051310.46906429
94Hedgehog signaling pathway_Homo sapiens_hsa043400.46487129
95Leukocyte transendothelial migration_Homo sapiens_hsa046700.46193943
96Toxoplasmosis_Homo sapiens_hsa051450.45568629
97AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.44763982
98Drug metabolism - other enzymes_Homo sapiens_hsa009830.44674731
992-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.44511924
100Fatty acid metabolism_Homo sapiens_hsa012120.43804352
101FoxO signaling pathway_Homo sapiens_hsa040680.43286443
102Influenza A_Homo sapiens_hsa051640.42727716
103Tight junction_Homo sapiens_hsa045300.41652897
104Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.41165214
105Metabolic pathways_Homo sapiens_hsa011000.40425940
106ECM-receptor interaction_Homo sapiens_hsa045120.40214771
107Arginine and proline metabolism_Homo sapiens_hsa003300.39234934
108Primary immunodeficiency_Homo sapiens_hsa053400.39148468
109NOD-like receptor signaling pathway_Homo sapiens_hsa046210.38872257
110Wnt signaling pathway_Homo sapiens_hsa043100.38757124
111Huntingtons disease_Homo sapiens_hsa050160.38403258
112Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.37807354
113B cell receptor signaling pathway_Homo sapiens_hsa046620.36910158
114Alcoholism_Homo sapiens_hsa050340.34672683
115Fructose and mannose metabolism_Homo sapiens_hsa000510.34536456
116T cell receptor signaling pathway_Homo sapiens_hsa046600.34431167
117Regulation of actin cytoskeleton_Homo sapiens_hsa048100.33413704
118Jak-STAT signaling pathway_Homo sapiens_hsa046300.32597731
119Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.32528729
120Dorso-ventral axis formation_Homo sapiens_hsa043200.31934821
121Neurotrophin signaling pathway_Homo sapiens_hsa047220.31589951
122Renal cell carcinoma_Homo sapiens_hsa052110.31110488
123PI3K-Akt signaling pathway_Homo sapiens_hsa041510.30762825
124Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.30582017
125VEGF signaling pathway_Homo sapiens_hsa043700.30569373
126Sulfur metabolism_Homo sapiens_hsa009200.28110166
127Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.27059612
128Sulfur relay system_Homo sapiens_hsa041220.26595946
129Butanoate metabolism_Homo sapiens_hsa006500.26586158
130Arginine biosynthesis_Homo sapiens_hsa002200.26243890
131Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.25975758
132Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.22614356
133Glucagon signaling pathway_Homo sapiens_hsa049220.20053932
134Parkinsons disease_Homo sapiens_hsa050120.19913936
135Circadian rhythm_Homo sapiens_hsa047100.17184911
136Galactose metabolism_Homo sapiens_hsa000520.17031990
137Pentose and glucuronate interconversions_Homo sapiens_hsa000400.15687752
138beta-Alanine metabolism_Homo sapiens_hsa004100.14721044
139Melanoma_Homo sapiens_hsa052180.12552874
140Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.11105904

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