

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | plasma membrane repair (GO:0001778) | 7.92689889 |
| 2 | regulation of skeletal muscle contraction (GO:0014819) | 7.86804526 |
| 3 | regulation of sarcomere organization (GO:0060297) | 7.59543193 |
| 4 | negative regulation of organelle assembly (GO:1902116) | 6.96671162 |
| 5 | negative regulation of nitric-oxide synthase activity (GO:0051001) | 6.95277759 |
| 6 | regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 6.56891082 |
| 7 | response to muscle activity (GO:0014850) | 6.50268929 |
| 8 | negative regulation of protein localization to cell surface (GO:2000009) | 6.48596691 |
| 9 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 6.05675005 |
| 10 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 5.96223888 |
| 11 | muscle cell cellular homeostasis (GO:0046716) | 5.93264218 |
| 12 | positive regulation of catecholamine secretion (GO:0033605) | 5.71063563 |
| 13 | membrane raft organization (GO:0031579) | 5.68454293 |
| 14 | negative regulation of muscle hypertrophy (GO:0014741) | 5.55806644 |
| 15 | regulation of p38MAPK cascade (GO:1900744) | 5.49952060 |
| 16 | negative regulation of cell size (GO:0045792) | 5.41967153 |
| 17 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 5.35500652 |
| 18 | regulation of autophagic vacuole assembly (GO:2000785) | 5.31418696 |
| 19 | myofibril assembly (GO:0030239) | 4.99843997 |
| 20 | coenzyme catabolic process (GO:0009109) | 4.93978572 |
| 21 | regulation of phosphoprotein phosphatase activity (GO:0043666) | 4.72956446 |
| 22 | negative regulation of heart growth (GO:0061117) | 4.66297494 |
| 23 | negative regulation of cardiac muscle tissue growth (GO:0055022) | 4.66297494 |
| 24 | negative regulation of cardiac muscle hypertrophy (GO:0010614) | 4.64520980 |
| 25 | regulation of phospholipase A2 activity (GO:0032429) | 4.57304639 |
| 26 | regulation of action potential (GO:0098900) | 4.49754315 |
| 27 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc | 4.49415051 |
| 28 | activation of protein kinase B activity (GO:0032148) | 4.48883713 |
| 29 | negative regulation of monooxygenase activity (GO:0032769) | 4.37943522 |
| 30 | cardiac myofibril assembly (GO:0055003) | 4.35630283 |
| 31 | ribonucleoprotein complex disassembly (GO:0032988) | 4.21941600 |
| 32 | primary alcohol catabolic process (GO:0034310) | 4.21513410 |
| 33 | striated muscle atrophy (GO:0014891) | 4.19834043 |
| 34 | regulation of vacuole organization (GO:0044088) | 4.18550159 |
| 35 | negative regulation of cardiac muscle cell apoptotic process (GO:0010667) | 4.08386478 |
| 36 | regulation of cardiac muscle cell differentiation (GO:2000725) | 4.02314324 |
| 37 | cGMP-mediated signaling (GO:0019934) | 4.01100345 |
| 38 | muscle atrophy (GO:0014889) | 3.99078054 |
| 39 | positive regulation of protein kinase C signaling (GO:0090037) | 3.98111446 |
| 40 | positive regulation of myotube differentiation (GO:0010831) | 3.92000056 |
| 41 | organelle disassembly (GO:1903008) | 3.87336594 |
| 42 | ventricular cardiac muscle cell action potential (GO:0086005) | 3.86171104 |
| 43 | cellular response to zinc ion (GO:0071294) | 3.85705660 |
| 44 | diacylglycerol metabolic process (GO:0046339) | 3.83745962 |
| 45 | negative regulation of cardiac muscle tissue development (GO:0055026) | 3.79058573 |
| 46 | ethanol metabolic process (GO:0006067) | 3.70800575 |
| 47 | regulation of oxidative stress-induced neuron death (GO:1903203) | 3.69427434 |
| 48 | muscle cell fate commitment (GO:0042693) | 3.67779825 |
| 49 | regulation of membrane repolarization (GO:0060306) | 3.66947448 |
| 50 | motile cilium assembly (GO:0044458) | 3.66395845 |
| 51 | AMP metabolic process (GO:0046033) | 3.64345056 |
| 52 | positive regulation of myoblast differentiation (GO:0045663) | 3.54340011 |
| 53 | regulation of transforming growth factor beta2 production (GO:0032909) | 3.52418473 |
| 54 | thyroid gland development (GO:0030878) | 3.50479509 |
| 55 | barbed-end actin filament capping (GO:0051016) | 3.46367791 |
| 56 | membrane assembly (GO:0071709) | 3.46307071 |
| 57 | potassium ion export (GO:0071435) | 3.42219617 |
| 58 | cellular response to lithium ion (GO:0071285) | 3.42074713 |
| 59 | cellular response to cadmium ion (GO:0071276) | 3.41671236 |
| 60 | relaxation of smooth muscle (GO:0044557) | 3.41645459 |
| 61 | protein localization to cell surface (GO:0034394) | 3.40373245 |
| 62 | mRNA cleavage (GO:0006379) | 3.37517854 |
| 63 | regulation of oxidative phosphorylation (GO:0002082) | 3.30121543 |
| 64 | TOR signaling (GO:0031929) | 3.26836476 |
| 65 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800) | 3.21217473 |
| 66 | positive regulation of microtubule polymerization (GO:0031116) | 3.21066914 |
| 67 | regulation of muscle hypertrophy (GO:0014743) | 3.17193638 |
| 68 | sarcomere organization (GO:0045214) | 3.11127908 |
| 69 | regulation of protein localization to cell surface (GO:2000008) | 3.08587395 |
| 70 | muscle filament sliding (GO:0030049) | 3.07275859 |
| 71 | actin-myosin filament sliding (GO:0033275) | 3.07275859 |
| 72 | myoblast migration (GO:0051451) | 3.05789615 |
| 73 | ADP metabolic process (GO:0046031) | 3.05598024 |
| 74 | negative regulation of striated muscle cell apoptotic process (GO:0010664) | 3.04679186 |
| 75 | muscle fiber development (GO:0048747) | 3.04404827 |
| 76 | regulation of alkaline phosphatase activity (GO:0010692) | 3.03786247 |
| 77 | regulation of protein kinase C signaling (GO:0090036) | 3.00540022 |
| 78 | negative regulation of smooth muscle cell proliferation (GO:0048662) | 3.00084860 |
| 79 | regulation of myoblast differentiation (GO:0045661) | 2.98289858 |
| 80 | heart trabecula formation (GO:0060347) | 2.97826858 |
| 81 | response to mercury ion (GO:0046689) | 2.95384116 |
| 82 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO | 2.95069637 |
| 83 | negative regulation of hydrogen peroxide-induced cell death (GO:1903206) | 2.93200687 |
| 84 | multicellular organism reproduction (GO:0032504) | 2.91885475 |
| 85 | myoblast fusion (GO:0007520) | 2.91246087 |
| 86 | androgen biosynthetic process (GO:0006702) | 2.85944530 |
| 87 | actin-mediated cell contraction (GO:0070252) | 2.81976527 |
| 88 | paraxial mesoderm development (GO:0048339) | 2.81493089 |
| 89 | negative regulation of potassium ion transport (GO:0043267) | 2.78327538 |
| 90 | regulation of cardiac muscle hypertrophy (GO:0010611) | 2.76417331 |
| 91 | skeletal muscle adaptation (GO:0043501) | 2.75285922 |
| 92 | cellular response to toxic substance (GO:0097237) | 2.72889113 |
| 93 | striated muscle adaptation (GO:0014888) | 2.72198020 |
| 94 | embryonic viscerocranium morphogenesis (GO:0048703) | 2.66669626 |
| 95 | negative regulation of striated muscle cell differentiation (GO:0051154) | 2.66236674 |
| 96 | regulation of hydrogen peroxide-induced cell death (GO:1903205) | 2.65232335 |
| 97 | regulation of hippo signaling (GO:0035330) | 2.65041961 |
| 98 | syncytium formation by plasma membrane fusion (GO:0000768) | 2.64652001 |
| 99 | regulation of ARF GTPase activity (GO:0032312) | 2.63269871 |
| 100 | oligosaccharide biosynthetic process (GO:0009312) | 2.62750439 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 9.15974278 |
| 2 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 6.92668604 |
| 3 | GATA1_22025678_ChIP-Seq_K562_Human | 5.53705614 |
| 4 | VDR_22108803_ChIP-Seq_LS180_Human | 4.64274023 |
| 5 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 4.15146962 |
| 6 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 3.90382197 |
| 7 | IGF1R_20145208_ChIP-Seq_DFB_Human | 3.68195808 |
| 8 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.73456308 |
| 9 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 2.51937261 |
| 10 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 2.51937261 |
| 11 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 2.51937261 |
| 12 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.45888807 |
| 13 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.43987485 |
| 14 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.36971055 |
| 15 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.79183261 |
| 16 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.77100579 |
| 17 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.74052435 |
| 18 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.73214424 |
| 19 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.72348941 |
| 20 | CJUN_26792858_Chip-Seq_BT549_Human | 1.69846960 |
| 21 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.64476352 |
| 22 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.63744569 |
| 23 | SPI1_20517297_ChIP-Seq_HL60_Human | 1.61338057 |
| 24 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.58059936 |
| 25 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.52882779 |
| 26 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.43382909 |
| 27 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.41195287 |
| 28 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 1.39252549 |
| 29 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.33192565 |
| 30 | RXR_22108803_ChIP-Seq_LS180_Human | 1.26693600 |
| 31 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 1.23267001 |
| 32 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.23143709 |
| 33 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.20164696 |
| 34 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.19124662 |
| 35 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.18354869 |
| 36 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.17273750 |
| 37 | RAC3_21632823_ChIP-Seq_H3396_Human | 1.16791548 |
| 38 | ERA_21632823_ChIP-Seq_H3396_Human | 1.16609780 |
| 39 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.15144922 |
| 40 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.14527443 |
| 41 | CBP_21632823_ChIP-Seq_H3396_Human | 1.14262342 |
| 42 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.10864852 |
| 43 | MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 1.10131520 |
| 44 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.09100973 |
| 45 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.08744692 |
| 46 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.08557635 |
| 47 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.06980027 |
| 48 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.04665974 |
| 49 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.02352093 |
| 50 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.02352093 |
| 51 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.01663228 |
| 52 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.01663228 |
| 53 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.01205221 |
| 54 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.00142161 |
| 55 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.99087725 |
| 56 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.98190684 |
| 57 | CTCF_21964334_ChIP-Seq_BJAB-B_Human | 0.97982895 |
| 58 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.97196691 |
| 59 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.96627211 |
| 60 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.92838040 |
| 61 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 0.89993549 |
| 62 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 0.89993549 |
| 63 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 0.89465575 |
| 64 | CTCF_21964334_Chip-Seq_Bcells_Human | 0.89213654 |
| 65 | OCT4_20526341_ChIP-Seq_ESCs_Human | 0.88490514 |
| 66 | OCT1_27270436_Chip-Seq_PROSTATE_Human | 0.88329277 |
| 67 | FUS_26573619_Chip-Seq_HEK293_Human | 0.86597515 |
| 68 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 0.85308197 |
| 69 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 0.85063011 |
| 70 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.84556099 |
| 71 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 0.84501427 |
| 72 | CSB_26484114_Chip-Seq_FIBROBLAST_Human | 0.84318822 |
| 73 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.83129043 |
| 74 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.83126849 |
| 75 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.82902911 |
| 76 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 0.81391767 |
| 77 | SMC4_20622854_ChIP-Seq_HELA_Human | 0.81286372 |
| 78 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.81148919 |
| 79 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.81148919 |
| 80 | TP53_18474530_ChIP-ChIP_U2OS_Human | 0.80603306 |
| 81 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.80508512 |
| 82 | BRD4_25478319_ChIP-Seq_HGPS_Human | 0.80415921 |
| 83 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.78253034 |
| 84 | STAT1_17558387_ChIP-Seq_HELA_Human | 0.76910428 |
| 85 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 0.76474327 |
| 86 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.76306890 |
| 87 | HNFA_21074721_ChIP-Seq_CACO-2_Human | 0.76258171 |
| 88 | TBL1_22424771_ChIP-Seq_293T_Human | 0.76236900 |
| 89 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.75760288 |
| 90 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.75530276 |
| 91 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.74882610 |
| 92 | P63_20808887_ChIP-Seq_KERATINOCYTES_Human | 0.74727460 |
| 93 | P300_19829295_ChIP-Seq_ESCs_Human | 0.74189459 |
| 94 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.73189636 |
| 95 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.73035904 |
| 96 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 0.71124516 |
| 97 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.70596754 |
| 98 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.70235748 |
| 99 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.69799060 |
| 100 | NFYB_21822215_ChIP-Seq_K562_Human | 0.69635399 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003950_abnormal_plasma_membrane | 6.12962712 |
| 2 | MP0000749_muscle_degeneration | 5.82108364 |
| 3 | MP0004084_abnormal_cardiac_muscle | 4.57843957 |
| 4 | MP0000751_myopathy | 3.78573550 |
| 5 | MP0004272_abnormal_basement_membrane | 3.48055680 |
| 6 | MP0010368_abnormal_lymphatic_system | 3.35176541 |
| 7 | MP0003806_abnormal_nucleotide_metabolis | 3.30383420 |
| 8 | MP0002102_abnormal_ear_morphology | 3.03738558 |
| 9 | MP0004036_abnormal_muscle_relaxation | 2.96833684 |
| 10 | MP0003315_abnormal_perineum_morphology | 2.93617854 |
| 11 | MP0002837_dystrophic_cardiac_calcinosis | 2.82508552 |
| 12 | MP0008004_abnormal_stomach_pH | 2.81671245 |
| 13 | MP0005330_cardiomyopathy | 2.44552773 |
| 14 | MP0003828_pulmonary_edema | 2.29351881 |
| 15 | MP0002269_muscular_atrophy | 2.11189340 |
| 16 | MP0002160_abnormal_reproductive_system | 2.01150678 |
| 17 | MP0001849_ear_inflammation | 1.88238997 |
| 18 | MP0002108_abnormal_muscle_morphology | 1.87262486 |
| 19 | MP0004087_abnormal_muscle_fiber | 1.82230977 |
| 20 | MP0000759_abnormal_skeletal_muscle | 1.79195858 |
| 21 | MP0005620_abnormal_muscle_contractility | 1.78012625 |
| 22 | MP0004145_abnormal_muscle_electrophysio | 1.75909933 |
| 23 | MP0004215_abnormal_myocardial_fiber | 1.71921182 |
| 24 | MP0000537_abnormal_urethra_morphology | 1.70856038 |
| 25 | MP0006138_congestive_heart_failure | 1.68831726 |
| 26 | MP0009780_abnormal_chondrocyte_physiolo | 1.64696578 |
| 27 | MP0008775_abnormal_heart_ventricle | 1.60118913 |
| 28 | MP0005410_abnormal_fertilization | 1.55438830 |
| 29 | MP0000678_abnormal_parathyroid_gland | 1.53064521 |
| 30 | MP0000747_muscle_weakness | 1.51497185 |
| 31 | MP0005187_abnormal_penis_morphology | 1.50484164 |
| 32 | MP0003045_fibrosis | 1.49770582 |
| 33 | MP0009840_abnormal_foam_cell | 1.48971955 |
| 34 | MP0005385_cardiovascular_system_phenoty | 1.47643664 |
| 35 | MP0001544_abnormal_cardiovascular_syste | 1.47643664 |
| 36 | MP0009697_abnormal_copulation | 1.43629277 |
| 37 | MP0000750_abnormal_muscle_regeneration | 1.43424783 |
| 38 | MP0004484_altered_response_of | 1.40111841 |
| 39 | MP0002127_abnormal_cardiovascular_syste | 1.38229907 |
| 40 | MP0005360_urolithiasis | 1.36394706 |
| 41 | MP0002972_abnormal_cardiac_muscle | 1.36391990 |
| 42 | MP0001664_abnormal_digestion | 1.35645252 |
| 43 | MP0002132_abnormal_respiratory_system | 1.33168670 |
| 44 | MP0005394_taste/olfaction_phenotype | 1.26988057 |
| 45 | MP0005499_abnormal_olfactory_system | 1.26988057 |
| 46 | MP0003385_abnormal_body_wall | 1.23234104 |
| 47 | MP0005166_decreased_susceptibility_to | 1.22978381 |
| 48 | MP0002249_abnormal_larynx_morphology | 1.20352035 |
| 49 | MP0010630_abnormal_cardiac_muscle | 1.18802071 |
| 50 | MP0003763_abnormal_thymus_physiology | 1.16719817 |
| 51 | MP0005369_muscle_phenotype | 1.14024303 |
| 52 | MP0003868_abnormal_feces_composition | 1.08082444 |
| 53 | MP0008789_abnormal_olfactory_epithelium | 1.05037767 |
| 54 | MP0001661_extended_life_span | 1.00703630 |
| 55 | MP0002106_abnormal_muscle_physiology | 1.00576536 |
| 56 | MP0005595_abnormal_vascular_smooth | 0.99445543 |
| 57 | MP0005165_increased_susceptibility_to | 0.99276226 |
| 58 | MP0005503_abnormal_tendon_morphology | 0.98678123 |
| 59 | MP0003136_yellow_coat_color | 0.96180614 |
| 60 | MP0010386_abnormal_urinary_bladder | 0.96144433 |
| 61 | MP0000343_altered_response_to | 0.94475121 |
| 62 | MP0009785_altered_susceptibility_to | 0.93951528 |
| 63 | MP0006036_abnormal_mitochondrial_physio | 0.92743835 |
| 64 | MP0000733_abnormal_muscle_development | 0.92423011 |
| 65 | MP0001501_abnormal_sleep_pattern | 0.92416581 |
| 66 | MP0001879_abnormal_lymphatic_vessel | 0.92326366 |
| 67 | MP0003705_abnormal_hypodermis_morpholog | 0.91575400 |
| 68 | MP0001270_distended_abdomen | 0.89707661 |
| 69 | MP0005058_abnormal_lysosome_morphology | 0.87882492 |
| 70 | MP0004782_abnormal_surfactant_physiolog | 0.87173716 |
| 71 | MP0005389_reproductive_system_phenotype | 0.84141912 |
| 72 | MP0002332_abnormal_exercise_endurance | 0.83887323 |
| 73 | MP0010234_abnormal_vibrissa_follicle | 0.81893870 |
| 74 | MP0005647_abnormal_sex_gland | 0.80339321 |
| 75 | MP0010030_abnormal_orbit_morphology | 0.79384940 |
| 76 | MP0009250_abnormal_appendicular_skeleto | 0.78599779 |
| 77 | MP0004883_abnormal_blood_vessel | 0.77046166 |
| 78 | MP0002115_abnormal_skeleton_extremities | 0.76036708 |
| 79 | MP0003453_abnormal_keratinocyte_physiol | 0.74663775 |
| 80 | MP0000230_abnormal_systemic_arterial | 0.73161341 |
| 81 | MP0005319_abnormal_enzyme/_coenzyme | 0.70569316 |
| 82 | MP0001764_abnormal_homeostasis | 0.70426706 |
| 83 | MP0004085_abnormal_heartbeat | 0.69845738 |
| 84 | MP0005646_abnormal_pituitary_gland | 0.69274924 |
| 85 | MP0003646_muscle_fatigue | 0.68941182 |
| 86 | MP0000467_abnormal_esophagus_morphology | 0.68638698 |
| 87 | MP0001485_abnormal_pinna_reflex | 0.68230894 |
| 88 | MP0002971_abnormal_brown_adipose | 0.67650106 |
| 89 | MP0005334_abnormal_fat_pad | 0.67376052 |
| 90 | MP0006072_abnormal_retinal_apoptosis | 0.66597492 |
| 91 | MP0004381_abnormal_hair_follicle | 0.64067300 |
| 92 | MP0001873_stomach_inflammation | 0.62236259 |
| 93 | MP0002998_abnormal_bone_remodeling | 0.61052310 |
| 94 | MP0000685_abnormal_immune_system | 0.60855885 |
| 95 | MP0009115_abnormal_fat_cell | 0.60444550 |
| 96 | MP0004264_abnormal_extraembryonic_tissu | 0.58414882 |
| 97 | MP0002233_abnormal_nose_morphology | 0.58084430 |
| 98 | MP0000049_abnormal_middle_ear | 0.55624133 |
| 99 | MP0000681_abnormal_thyroid_gland | 0.55052700 |
| 100 | MP0000767_abnormal_smooth_muscle | 0.54478947 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Calf muscle hypertrophy (HP:0008981) | 8.51730278 |
| 2 | Exercise-induced myalgia (HP:0003738) | 8.49012812 |
| 3 | Exercise-induced muscle cramps (HP:0003710) | 7.75312420 |
| 4 | Muscle hypertrophy of the lower extremities (HP:0008968) | 7.66031160 |
| 5 | Subaortic stenosis (HP:0001682) | 5.73657273 |
| 6 | Abnormality of the left ventricular outflow tract (HP:0011103) | 5.73657273 |
| 7 | Hyporeflexia of lower limbs (HP:0002600) | 5.41781311 |
| 8 | Abnormality of the calf musculature (HP:0001430) | 5.14644196 |
| 9 | Sudden death (HP:0001699) | 5.14471954 |
| 10 | Asymmetric septal hypertrophy (HP:0001670) | 5.09985351 |
| 11 | Reduced antithrombin III activity (HP:0001976) | 4.69205210 |
| 12 | Muscle stiffness (HP:0003552) | 4.63640727 |
| 13 | Aortic aneurysm (HP:0004942) | 4.59037413 |
| 14 | Prolonged QT interval (HP:0001657) | 4.40934479 |
| 15 | Neck muscle weakness (HP:0000467) | 4.39725339 |
| 16 | Abnormality of the columella (HP:0009929) | 4.33012507 |
| 17 | Myotonia (HP:0002486) | 3.73098181 |
| 18 | Scapular winging (HP:0003691) | 3.37511718 |
| 19 | Renal cortical cysts (HP:0000803) | 3.34416052 |
| 20 | Spinal rigidity (HP:0003306) | 3.30734402 |
| 21 | Turricephaly (HP:0000262) | 3.17362320 |
| 22 | Aplasia/Hypoplasia of the frontal sinuses (HP:0009119) | 3.11022975 |
| 23 | Myopathic facies (HP:0002058) | 3.09044814 |
| 24 | Abnormality of the shoulder girdle musculature (HP:0001435) | 3.08164726 |
| 25 | Clumsiness (HP:0002312) | 3.03706616 |
| 26 | Thoracic kyphosis (HP:0002942) | 2.98756476 |
| 27 | Resting tremor (HP:0002322) | 2.95526631 |
| 28 | Hypoplasia of the thymus (HP:0000778) | 2.93707247 |
| 29 | Gowers sign (HP:0003391) | 2.89967668 |
| 30 | Popliteal pterygium (HP:0009756) | 2.81149217 |
| 31 | Ventricular fibrillation (HP:0001663) | 2.80122018 |
| 32 | Weak cry (HP:0001612) | 2.68955453 |
| 33 | Increased variability in muscle fiber diameter (HP:0003557) | 2.66848854 |
| 34 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.66605547 |
| 35 | Distal lower limb muscle weakness (HP:0009053) | 2.63744018 |
| 36 | Abnormal EKG (HP:0003115) | 2.62586771 |
| 37 | Ventricular arrhythmia (HP:0004308) | 2.54440453 |
| 38 | Abnormality of the frontal sinuses (HP:0002687) | 2.52417234 |
| 39 | Aplasia/Hypoplasia involving the sinuses (HP:0009120) | 2.50927310 |
| 40 | Easy fatigability (HP:0003388) | 2.49871303 |
| 41 | EMG: myopathic abnormalities (HP:0003458) | 2.49840486 |
| 42 | Difficulty walking (HP:0002355) | 2.47739641 |
| 43 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.46551690 |
| 44 | Proximal amyotrophy (HP:0007126) | 2.40298932 |
| 45 | Sensory axonal neuropathy (HP:0003390) | 2.37633984 |
| 46 | Arterial tortuosity (HP:0005116) | 2.35456685 |
| 47 | Nonprogressive disorder (HP:0003680) | 2.33171556 |
| 48 | Vascular tortuosity (HP:0004948) | 2.32615356 |
| 49 | Inability to walk (HP:0002540) | 2.30244050 |
| 50 | Areflexia of lower limbs (HP:0002522) | 2.30082036 |
| 51 | Bulbar palsy (HP:0001283) | 2.28453427 |
| 52 | Skin nodule (HP:0200036) | 2.26565625 |
| 53 | Aortic dissection (HP:0002647) | 2.24896532 |
| 54 | Malignant hyperthermia (HP:0002047) | 2.23980743 |
| 55 | Abnormality of skeletal muscle fiber size (HP:0012084) | 2.22846846 |
| 56 | Muscular dystrophy (HP:0003560) | 2.20307930 |
| 57 | Abnormality of DNA repair (HP:0003254) | 2.18075695 |
| 58 | Steppage gait (HP:0003376) | 2.15937660 |
| 59 | Right ventricular cardiomyopathy (HP:0011663) | 2.15279076 |
| 60 | Facial diplegia (HP:0001349) | 2.14419383 |
| 61 | Rhabdomyolysis (HP:0003201) | 2.14176852 |
| 62 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 2.13611662 |
| 63 | Aortic regurgitation (HP:0001659) | 2.10675309 |
| 64 | Type 2 muscle fiber atrophy (HP:0003554) | 2.07577912 |
| 65 | Muscle fiber inclusion bodies (HP:0100299) | 2.06924180 |
| 66 | Aplasia cutis congenita (HP:0001057) | 2.05540772 |
| 67 | Abnormality of the intrinsic pathway (HP:0010989) | 2.04619502 |
| 68 | Eosinophilia (HP:0001880) | 2.03594067 |
| 69 | Abnormality of the renal cortex (HP:0011035) | 2.01559799 |
| 70 | Myoglobinuria (HP:0002913) | 2.00393273 |
| 71 | Protrusio acetabuli (HP:0003179) | 1.98879522 |
| 72 | Rimmed vacuoles (HP:0003805) | 1.97986797 |
| 73 | Fatigable weakness (HP:0003473) | 1.97148927 |
| 74 | Abnormality of the neuromuscular junction (HP:0003398) | 1.97148927 |
| 75 | Type 1 muscle fiber predominance (HP:0003803) | 1.95960980 |
| 76 | Atrial fibrillation (HP:0005110) | 1.95332610 |
| 77 | High pitched voice (HP:0001620) | 1.95134362 |
| 78 | Recurrent corneal erosions (HP:0000495) | 1.94881300 |
| 79 | Diaphragmatic weakness (HP:0009113) | 1.94161822 |
| 80 | Benign neoplasm of the central nervous system (HP:0100835) | 1.90733419 |
| 81 | Urinary urgency (HP:0000012) | 1.90367554 |
| 82 | Muscle fiber splitting (HP:0003555) | 1.88779203 |
| 83 | Poor head control (HP:0002421) | 1.87641990 |
| 84 | Lipoatrophy (HP:0100578) | 1.85982275 |
| 85 | Flat cornea (HP:0007720) | 1.83690284 |
| 86 | Metatarsus adductus (HP:0001840) | 1.83624565 |
| 87 | Respiratory insufficiency due to muscle weakness (HP:0002747) | 1.80351788 |
| 88 | Abnormality of the thoracic spine (HP:0100711) | 1.78237218 |
| 89 | Thoracolumbar scoliosis (HP:0002944) | 1.77597538 |
| 90 | Small epiphyses (HP:0010585) | 1.76998681 |
| 91 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.73688246 |
| 92 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.73688246 |
| 93 | Primary atrial arrhythmia (HP:0001692) | 1.73463217 |
| 94 | Muscle fiber atrophy (HP:0100295) | 1.71538190 |
| 95 | Brushfield spots (HP:0001088) | 1.70302745 |
| 96 | Distal arthrogryposis (HP:0005684) | 1.69909016 |
| 97 | Spondylolisthesis (HP:0003302) | 1.68128615 |
| 98 | High anterior hairline (HP:0009890) | 1.64165551 |
| 99 | Chronic hepatic failure (HP:0100626) | 1.63440790 |
| 100 | Frequent falls (HP:0002359) | 1.63434786 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | PINK1 | 7.62908271 |
| 2 | MARK3 | 4.22348755 |
| 3 | MAPKAPK5 | 4.00089857 |
| 4 | MUSK | 3.71616821 |
| 5 | OBSCN | 3.44716173 |
| 6 | MYLK | 3.43028262 |
| 7 | LATS1 | 3.26955484 |
| 8 | CDK8 | 2.62051498 |
| 9 | NEK2 | 2.36282181 |
| 10 | MAPKAPK3 | 2.18710411 |
| 11 | MOS | 2.17947585 |
| 12 | TLK1 | 2.14807359 |
| 13 | CCNB1 | 2.14217588 |
| 14 | NME2 | 2.09307399 |
| 15 | STK38L | 2.05537295 |
| 16 | LATS2 | 2.03075095 |
| 17 | EIF2AK3 | 1.86939169 |
| 18 | TIE1 | 1.79153893 |
| 19 | MELK | 1.75883856 |
| 20 | ZAK | 1.72867668 |
| 21 | MAP2K7 | 1.55695816 |
| 22 | EEF2K | 1.34023970 |
| 23 | CSNK1A1L | 1.33626095 |
| 24 | MAP3K7 | 1.18983266 |
| 25 | FRK | 1.15854159 |
| 26 | PAK2 | 1.12919931 |
| 27 | MAPK12 | 1.03002739 |
| 28 | CDK3 | 1.01429467 |
| 29 | CSNK1G3 | 0.99367584 |
| 30 | PKN2 | 0.98764491 |
| 31 | PRKG2 | 0.98122273 |
| 32 | CLK1 | 0.94841443 |
| 33 | MAP3K13 | 0.94593291 |
| 34 | TGFBR1 | 0.91255262 |
| 35 | GRK1 | 0.85262514 |
| 36 | ARAF | 0.84751676 |
| 37 | CSNK1G2 | 0.79370928 |
| 38 | SGK223 | 0.79032540 |
| 39 | SGK494 | 0.79032540 |
| 40 | CDC42BPA | 0.78471010 |
| 41 | ADRBK2 | 0.76741891 |
| 42 | MAP3K10 | 0.75219158 |
| 43 | RPS6KB1 | 0.70180091 |
| 44 | MAP3K1 | 0.69886848 |
| 45 | PIK3CA | 0.68017808 |
| 46 | PIK3CG | 0.67345450 |
| 47 | CSNK1G1 | 0.67188778 |
| 48 | MAPK15 | 0.64944615 |
| 49 | STK38 | 0.64472898 |
| 50 | DAPK3 | 0.63773879 |
| 51 | CDK9 | 0.63633588 |
| 52 | RPS6KA5 | 0.63268601 |
| 53 | DMPK | 0.62515948 |
| 54 | DYRK3 | 0.61221016 |
| 55 | BMPR1B | 0.60813379 |
| 56 | STK3 | 0.58160342 |
| 57 | MST1R | 0.57913957 |
| 58 | GRK5 | 0.57429071 |
| 59 | PRKCQ | 0.55573786 |
| 60 | PAK1 | 0.53656085 |
| 61 | ZAP70 | 0.53123382 |
| 62 | AKT2 | 0.52997458 |
| 63 | PAK6 | 0.50579789 |
| 64 | TNK2 | 0.49548400 |
| 65 | ILK | 0.47871722 |
| 66 | PRKACB | 0.47407107 |
| 67 | TRPM7 | 0.45845535 |
| 68 | ROCK1 | 0.45629923 |
| 69 | BTK | 0.44375724 |
| 70 | PHKG2 | 0.43894298 |
| 71 | PHKG1 | 0.43894298 |
| 72 | SGK2 | 0.38857202 |
| 73 | CSNK1D | 0.38579907 |
| 74 | DDR2 | 0.38146103 |
| 75 | MTOR | 0.37673525 |
| 76 | CDK4 | 0.36500006 |
| 77 | EGFR | 0.35489673 |
| 78 | NLK | 0.34942572 |
| 79 | CDK14 | 0.34638614 |
| 80 | MAP3K5 | 0.34441486 |
| 81 | NME1 | 0.34083330 |
| 82 | CAMK1 | 0.32235650 |
| 83 | CSNK1A1 | 0.31599693 |
| 84 | SCYL2 | 0.31451351 |
| 85 | FGFR2 | 0.28935878 |
| 86 | MARK2 | 0.26757410 |
| 87 | PKN1 | 0.26233719 |
| 88 | MAPK4 | 0.25817591 |
| 89 | ICK | 0.25407562 |
| 90 | NEK9 | 0.25185040 |
| 91 | AURKB | 0.24978837 |
| 92 | MAP3K9 | 0.22781128 |
| 93 | BLK | 0.20961988 |
| 94 | PDPK1 | 0.20780761 |
| 95 | PTK2B | 0.20352681 |
| 96 | TRIB3 | 0.19369410 |
| 97 | TGFBR2 | 0.19185563 |
| 98 | CAMK2D | 0.18373177 |
| 99 | RET | 0.18071732 |
| 100 | AURKA | 0.17808074 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Olfactory transduction_Homo sapiens_hsa04740 | 3.16960203 |
| 2 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 3.14992717 |
| 3 | Histidine metabolism_Homo sapiens_hsa00340 | 2.98218882 |
| 4 | Pyruvate metabolism_Homo sapiens_hsa00620 | 2.76237181 |
| 5 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 2.51550722 |
| 6 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 2.37810969 |
| 7 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 2.33389424 |
| 8 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 2.18052781 |
| 9 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.15741991 |
| 10 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 2.12142909 |
| 11 | Gap junction_Homo sapiens_hsa04540 | 2.10753082 |
| 12 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 2.03297670 |
| 13 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.00153963 |
| 14 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 2.00089642 |
| 15 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.98190398 |
| 16 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.86702446 |
| 17 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.81467915 |
| 18 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.80566907 |
| 19 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.77222435 |
| 20 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.73364422 |
| 21 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.70701421 |
| 22 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.67769187 |
| 23 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.62482467 |
| 24 | ABC transporters_Homo sapiens_hsa02010 | 1.60633840 |
| 25 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.59869914 |
| 26 | Renin secretion_Homo sapiens_hsa04924 | 1.57149977 |
| 27 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.53488290 |
| 28 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.51913373 |
| 29 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.51771911 |
| 30 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.49537211 |
| 31 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.47286872 |
| 32 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.44968785 |
| 33 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.43487436 |
| 34 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.42307418 |
| 35 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.40498669 |
| 36 | Apoptosis_Homo sapiens_hsa04210 | 1.34662117 |
| 37 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.33019479 |
| 38 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.32653354 |
| 39 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.22763118 |
| 40 | Circadian rhythm_Homo sapiens_hsa04710 | 1.20634312 |
| 41 | Focal adhesion_Homo sapiens_hsa04510 | 1.14121573 |
| 42 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.10743405 |
| 43 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.00726754 |
| 44 | Retinol metabolism_Homo sapiens_hsa00830 | 0.98740972 |
| 45 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.93760896 |
| 46 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.88417426 |
| 47 | Phagosome_Homo sapiens_hsa04145 | 0.86211489 |
| 48 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.85475960 |
| 49 | Malaria_Homo sapiens_hsa05144 | 0.82723033 |
| 50 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.81335999 |
| 51 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.80861956 |
| 52 | Phototransduction_Homo sapiens_hsa04744 | 0.80133037 |
| 53 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.79773012 |
| 54 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.79055101 |
| 55 | Taste transduction_Homo sapiens_hsa04742 | 0.77883409 |
| 56 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.77676477 |
| 57 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.76227149 |
| 58 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.76110024 |
| 59 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.74585290 |
| 60 | Salivary secretion_Homo sapiens_hsa04970 | 0.73345401 |
| 61 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.73093008 |
| 62 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.72312098 |
| 63 | Viral myocarditis_Homo sapiens_hsa05416 | 0.70368114 |
| 64 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.68761275 |
| 65 | Mineral absorption_Homo sapiens_hsa04978 | 0.68137359 |
| 66 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.63661077 |
| 67 | Alcoholism_Homo sapiens_hsa05034 | 0.63152942 |
| 68 | Lysine degradation_Homo sapiens_hsa00310 | 0.59803180 |
| 69 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.58231196 |
| 70 | Purine metabolism_Homo sapiens_hsa00230 | 0.57471103 |
| 71 | Peroxisome_Homo sapiens_hsa04146 | 0.56887396 |
| 72 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.53681028 |
| 73 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.53174135 |
| 74 | Asthma_Homo sapiens_hsa05310 | 0.53119250 |
| 75 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.52982168 |
| 76 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.51896903 |
| 77 | Circadian entrainment_Homo sapiens_hsa04713 | 0.51408449 |
| 78 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.49029348 |
| 79 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.46908172 |
| 80 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.46798085 |
| 81 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.46725521 |
| 82 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.46042159 |
| 83 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.44837624 |
| 84 | Adherens junction_Homo sapiens_hsa04520 | 0.42697474 |
| 85 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.42115775 |
| 86 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.41837999 |
| 87 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.40869998 |
| 88 | Pertussis_Homo sapiens_hsa05133 | 0.40713546 |
| 89 | Insulin resistance_Homo sapiens_hsa04931 | 0.38629314 |
| 90 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.36695756 |
| 91 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.36180140 |
| 92 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.34764881 |
| 93 | Melanogenesis_Homo sapiens_hsa04916 | 0.33980434 |
| 94 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.32414478 |
| 95 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.32036027 |
| 96 | RNA degradation_Homo sapiens_hsa03018 | 0.30445764 |
| 97 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.29555572 |
| 98 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.28341017 |
| 99 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.27594572 |
| 100 | Tight junction_Homo sapiens_hsa04530 | 0.27436363 |

