BMS1P3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1plasma membrane repair (GO:0001778)7.92689889
2regulation of skeletal muscle contraction (GO:0014819)7.86804526
3regulation of sarcomere organization (GO:0060297)7.59543193
4negative regulation of organelle assembly (GO:1902116)6.96671162
5negative regulation of nitric-oxide synthase activity (GO:0051001)6.95277759
6regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)6.56891082
7response to muscle activity (GO:0014850)6.50268929
8negative regulation of protein localization to cell surface (GO:2000009)6.48596691
9negative regulation of potassium ion transmembrane transporter activity (GO:1901017)6.05675005
10positive regulation of synaptic transmission, dopaminergic (GO:0032226)5.96223888
11muscle cell cellular homeostasis (GO:0046716)5.93264218
12positive regulation of catecholamine secretion (GO:0033605)5.71063563
13membrane raft organization (GO:0031579)5.68454293
14negative regulation of muscle hypertrophy (GO:0014741)5.55806644
15regulation of p38MAPK cascade (GO:1900744)5.49952060
16negative regulation of cell size (GO:0045792)5.41967153
17negative regulation of potassium ion transmembrane transport (GO:1901380)5.35500652
18regulation of autophagic vacuole assembly (GO:2000785)5.31418696
19myofibril assembly (GO:0030239)4.99843997
20coenzyme catabolic process (GO:0009109)4.93978572
21regulation of phosphoprotein phosphatase activity (GO:0043666)4.72956446
22negative regulation of heart growth (GO:0061117)4.66297494
23negative regulation of cardiac muscle tissue growth (GO:0055022)4.66297494
24negative regulation of cardiac muscle hypertrophy (GO:0010614)4.64520980
25regulation of phospholipase A2 activity (GO:0032429)4.57304639
26regulation of action potential (GO:0098900)4.49754315
27positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc4.49415051
28activation of protein kinase B activity (GO:0032148)4.48883713
29negative regulation of monooxygenase activity (GO:0032769)4.37943522
30cardiac myofibril assembly (GO:0055003)4.35630283
31ribonucleoprotein complex disassembly (GO:0032988)4.21941600
32primary alcohol catabolic process (GO:0034310)4.21513410
33striated muscle atrophy (GO:0014891)4.19834043
34regulation of vacuole organization (GO:0044088)4.18550159
35negative regulation of cardiac muscle cell apoptotic process (GO:0010667)4.08386478
36regulation of cardiac muscle cell differentiation (GO:2000725)4.02314324
37cGMP-mediated signaling (GO:0019934)4.01100345
38muscle atrophy (GO:0014889)3.99078054
39positive regulation of protein kinase C signaling (GO:0090037)3.98111446
40positive regulation of myotube differentiation (GO:0010831)3.92000056
41organelle disassembly (GO:1903008)3.87336594
42ventricular cardiac muscle cell action potential (GO:0086005)3.86171104
43cellular response to zinc ion (GO:0071294)3.85705660
44diacylglycerol metabolic process (GO:0046339)3.83745962
45negative regulation of cardiac muscle tissue development (GO:0055026)3.79058573
46ethanol metabolic process (GO:0006067)3.70800575
47regulation of oxidative stress-induced neuron death (GO:1903203)3.69427434
48muscle cell fate commitment (GO:0042693)3.67779825
49regulation of membrane repolarization (GO:0060306)3.66947448
50motile cilium assembly (GO:0044458)3.66395845
51AMP metabolic process (GO:0046033)3.64345056
52positive regulation of myoblast differentiation (GO:0045663)3.54340011
53regulation of transforming growth factor beta2 production (GO:0032909)3.52418473
54thyroid gland development (GO:0030878)3.50479509
55barbed-end actin filament capping (GO:0051016)3.46367791
56membrane assembly (GO:0071709)3.46307071
57potassium ion export (GO:0071435)3.42219617
58cellular response to lithium ion (GO:0071285)3.42074713
59cellular response to cadmium ion (GO:0071276)3.41671236
60relaxation of smooth muscle (GO:0044557)3.41645459
61protein localization to cell surface (GO:0034394)3.40373245
62mRNA cleavage (GO:0006379)3.37517854
63regulation of oxidative phosphorylation (GO:0002082)3.30121543
64TOR signaling (GO:0031929)3.26836476
65peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)3.21217473
66positive regulation of microtubule polymerization (GO:0031116)3.21066914
67regulation of muscle hypertrophy (GO:0014743)3.17193638
68sarcomere organization (GO:0045214)3.11127908
69regulation of protein localization to cell surface (GO:2000008)3.08587395
70muscle filament sliding (GO:0030049)3.07275859
71actin-myosin filament sliding (GO:0033275)3.07275859
72myoblast migration (GO:0051451)3.05789615
73ADP metabolic process (GO:0046031)3.05598024
74negative regulation of striated muscle cell apoptotic process (GO:0010664)3.04679186
75muscle fiber development (GO:0048747)3.04404827
76regulation of alkaline phosphatase activity (GO:0010692)3.03786247
77regulation of protein kinase C signaling (GO:0090036)3.00540022
78negative regulation of smooth muscle cell proliferation (GO:0048662)3.00084860
79regulation of myoblast differentiation (GO:0045661)2.98289858
80heart trabecula formation (GO:0060347)2.97826858
81response to mercury ion (GO:0046689)2.95384116
82activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO2.95069637
83negative regulation of hydrogen peroxide-induced cell death (GO:1903206)2.93200687
84multicellular organism reproduction (GO:0032504)2.91885475
85myoblast fusion (GO:0007520)2.91246087
86androgen biosynthetic process (GO:0006702)2.85944530
87actin-mediated cell contraction (GO:0070252)2.81976527
88paraxial mesoderm development (GO:0048339)2.81493089
89negative regulation of potassium ion transport (GO:0043267)2.78327538
90regulation of cardiac muscle hypertrophy (GO:0010611)2.76417331
91skeletal muscle adaptation (GO:0043501)2.75285922
92cellular response to toxic substance (GO:0097237)2.72889113
93striated muscle adaptation (GO:0014888)2.72198020
94embryonic viscerocranium morphogenesis (GO:0048703)2.66669626
95negative regulation of striated muscle cell differentiation (GO:0051154)2.66236674
96regulation of hydrogen peroxide-induced cell death (GO:1903205)2.65232335
97regulation of hippo signaling (GO:0035330)2.65041961
98syncytium formation by plasma membrane fusion (GO:0000768)2.64652001
99regulation of ARF GTPase activity (GO:0032312)2.63269871
100oligosaccharide biosynthetic process (GO:0009312)2.62750439

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse9.15974278
2BP1_19119308_ChIP-ChIP_Hs578T_Human6.92668604
3GATA1_22025678_ChIP-Seq_K562_Human5.53705614
4VDR_22108803_ChIP-Seq_LS180_Human4.64274023
5HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse4.15146962
6ESR1_20079471_ChIP-ChIP_T-47D_Human3.90382197
7IGF1R_20145208_ChIP-Seq_DFB_Human3.68195808
8IRF8_22096565_ChIP-ChIP_GC-B_Human2.73456308
9KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.51937261
10KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.51937261
11KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.51937261
12ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.45888807
13E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.43987485
14GBX2_23144817_ChIP-Seq_PC3_Human2.36971055
15SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.79183261
16ER_23166858_ChIP-Seq_MCF-7_Human1.77100579
17CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.74052435
18PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.73214424
19ZNF263_19887448_ChIP-Seq_K562_Human1.72348941
20CJUN_26792858_Chip-Seq_BT549_Human1.69846960
21ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.64476352
22ZNF274_21170338_ChIP-Seq_K562_Hela1.63744569
23SPI1_20517297_ChIP-Seq_HL60_Human1.61338057
24IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.58059936
25AR_21572438_ChIP-Seq_LNCaP_Human1.52882779
26EP300_21415370_ChIP-Seq_HL-1_Mouse1.43382909
27CTBP1_25329375_ChIP-Seq_LNCAP_Human1.41195287
28WDR5_24793694_ChIP-Seq_LNCAP_Human1.39252549
29PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.33192565
30RXR_22108803_ChIP-Seq_LS180_Human1.26693600
31RAD21_21589869_ChIP-Seq_MESCs_Mouse1.23267001
32TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.23143709
33VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.20164696
34CTCF_27219007_Chip-Seq_Bcells_Human1.19124662
35TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.18354869
36KLF5_20875108_ChIP-Seq_MESCs_Mouse1.17273750
37RAC3_21632823_ChIP-Seq_H3396_Human1.16791548
38ERA_21632823_ChIP-Seq_H3396_Human1.16609780
39VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.15144922
40PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.14527443
41CBP_21632823_ChIP-Seq_H3396_Human1.14262342
42AHR_22903824_ChIP-Seq_MCF-7_Human1.10864852
43MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.10131520
44CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.09100973
45GATA1_26923725_Chip-Seq_HPCs_Mouse1.08744692
46ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.08557635
47SMAD_19615063_ChIP-ChIP_OVARY_Human1.06980027
48CTBP2_25329375_ChIP-Seq_LNCAP_Human1.04665974
49TBX20_22328084_ChIP-Seq_HEART_Mouse1.02352093
50TBX20_22080862_ChIP-Seq_HEART_Mouse1.02352093
51TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01663228
52POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.01663228
53PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.01205221
54NANOG_20526341_ChIP-Seq_ESCs_Human1.00142161
55CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.99087725
56CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.98190684
57CTCF_21964334_ChIP-Seq_BJAB-B_Human0.97982895
58ESR2_21235772_ChIP-Seq_MCF-7_Human0.97196691
59TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.96627211
60STAT1_20625510_ChIP-Seq_HELA_Human0.92838040
61RNF2_18974828_ChIP-Seq_MESCs_Mouse0.89993549
62EZH2_18974828_ChIP-Seq_MESCs_Mouse0.89993549
63PPAR_26484153_Chip-Seq_NCI-H1993_Human0.89465575
64CTCF_21964334_Chip-Seq_Bcells_Human0.89213654
65OCT4_20526341_ChIP-Seq_ESCs_Human0.88490514
66OCT1_27270436_Chip-Seq_PROSTATE_Human0.88329277
67FUS_26573619_Chip-Seq_HEK293_Human0.86597515
68RARG_19884340_ChIP-ChIP_MEFs_Mouse0.85308197
69SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.85063011
70GATA2_21666600_ChIP-Seq_HMVEC_Human0.84556099
71TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.84501427
72CSB_26484114_Chip-Seq_FIBROBLAST_Human0.84318822
73JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.83129043
74ARNT_22903824_ChIP-Seq_MCF-7_Human0.83126849
75JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.82902911
76MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.81391767
77SMC4_20622854_ChIP-Seq_HELA_Human0.81286372
78IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.81148919
79CBP_20019798_ChIP-Seq_JUKART_Human0.81148919
80TP53_18474530_ChIP-ChIP_U2OS_Human0.80603306
81ELF5_23300383_ChIP-Seq_T47D_Human0.80508512
82BRD4_25478319_ChIP-Seq_HGPS_Human0.80415921
83TOP2B_26459242_ChIP-Seq_MCF-7_Human0.78253034
84STAT1_17558387_ChIP-Seq_HELA_Human0.76910428
85ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.76474327
86TDRD3_21172665_ChIP-Seq_MCF-7_Human0.76306890
87HNFA_21074721_ChIP-Seq_CACO-2_Human0.76258171
88TBL1_22424771_ChIP-Seq_293T_Human0.76236900
89MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.75760288
90MYC_19829295_ChIP-Seq_ESCs_Human0.75530276
91SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.74882610
92P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.74727460
93P300_19829295_ChIP-Seq_ESCs_Human0.74189459
94ZNF217_24962896_ChIP-Seq_MCF-7_Human0.73189636
95GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.73035904
96RUNX1_27514584_Chip-Seq_MCF-7_Human0.71124516
97FOXH1_21741376_ChIP-Seq_ESCs_Human0.70596754
98UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.70235748
99TP53_20018659_ChIP-ChIP_R1E_Mouse0.69799060
100NFYB_21822215_ChIP-Seq_K562_Human0.69635399

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003950_abnormal_plasma_membrane6.12962712
2MP0000749_muscle_degeneration5.82108364
3MP0004084_abnormal_cardiac_muscle4.57843957
4MP0000751_myopathy3.78573550
5MP0004272_abnormal_basement_membrane3.48055680
6MP0010368_abnormal_lymphatic_system3.35176541
7MP0003806_abnormal_nucleotide_metabolis3.30383420
8MP0002102_abnormal_ear_morphology3.03738558
9MP0004036_abnormal_muscle_relaxation2.96833684
10MP0003315_abnormal_perineum_morphology2.93617854
11MP0002837_dystrophic_cardiac_calcinosis2.82508552
12MP0008004_abnormal_stomach_pH2.81671245
13MP0005330_cardiomyopathy2.44552773
14MP0003828_pulmonary_edema2.29351881
15MP0002269_muscular_atrophy2.11189340
16MP0002160_abnormal_reproductive_system2.01150678
17MP0001849_ear_inflammation1.88238997
18MP0002108_abnormal_muscle_morphology1.87262486
19MP0004087_abnormal_muscle_fiber1.82230977
20MP0000759_abnormal_skeletal_muscle1.79195858
21MP0005620_abnormal_muscle_contractility1.78012625
22MP0004145_abnormal_muscle_electrophysio1.75909933
23MP0004215_abnormal_myocardial_fiber1.71921182
24MP0000537_abnormal_urethra_morphology1.70856038
25MP0006138_congestive_heart_failure1.68831726
26MP0009780_abnormal_chondrocyte_physiolo1.64696578
27MP0008775_abnormal_heart_ventricle1.60118913
28MP0005410_abnormal_fertilization1.55438830
29MP0000678_abnormal_parathyroid_gland1.53064521
30MP0000747_muscle_weakness1.51497185
31MP0005187_abnormal_penis_morphology1.50484164
32MP0003045_fibrosis1.49770582
33MP0009840_abnormal_foam_cell1.48971955
34MP0005385_cardiovascular_system_phenoty1.47643664
35MP0001544_abnormal_cardiovascular_syste1.47643664
36MP0009697_abnormal_copulation1.43629277
37MP0000750_abnormal_muscle_regeneration1.43424783
38MP0004484_altered_response_of1.40111841
39MP0002127_abnormal_cardiovascular_syste1.38229907
40MP0005360_urolithiasis1.36394706
41MP0002972_abnormal_cardiac_muscle1.36391990
42MP0001664_abnormal_digestion1.35645252
43MP0002132_abnormal_respiratory_system1.33168670
44MP0005394_taste/olfaction_phenotype1.26988057
45MP0005499_abnormal_olfactory_system1.26988057
46MP0003385_abnormal_body_wall1.23234104
47MP0005166_decreased_susceptibility_to1.22978381
48MP0002249_abnormal_larynx_morphology1.20352035
49MP0010630_abnormal_cardiac_muscle1.18802071
50MP0003763_abnormal_thymus_physiology1.16719817
51MP0005369_muscle_phenotype1.14024303
52MP0003868_abnormal_feces_composition1.08082444
53MP0008789_abnormal_olfactory_epithelium1.05037767
54MP0001661_extended_life_span1.00703630
55MP0002106_abnormal_muscle_physiology1.00576536
56MP0005595_abnormal_vascular_smooth0.99445543
57MP0005165_increased_susceptibility_to0.99276226
58MP0005503_abnormal_tendon_morphology0.98678123
59MP0003136_yellow_coat_color0.96180614
60MP0010386_abnormal_urinary_bladder0.96144433
61MP0000343_altered_response_to0.94475121
62MP0009785_altered_susceptibility_to0.93951528
63MP0006036_abnormal_mitochondrial_physio0.92743835
64MP0000733_abnormal_muscle_development0.92423011
65MP0001501_abnormal_sleep_pattern0.92416581
66MP0001879_abnormal_lymphatic_vessel0.92326366
67MP0003705_abnormal_hypodermis_morpholog0.91575400
68MP0001270_distended_abdomen0.89707661
69MP0005058_abnormal_lysosome_morphology0.87882492
70MP0004782_abnormal_surfactant_physiolog0.87173716
71MP0005389_reproductive_system_phenotype0.84141912
72MP0002332_abnormal_exercise_endurance0.83887323
73MP0010234_abnormal_vibrissa_follicle0.81893870
74MP0005647_abnormal_sex_gland0.80339321
75MP0010030_abnormal_orbit_morphology0.79384940
76MP0009250_abnormal_appendicular_skeleto0.78599779
77MP0004883_abnormal_blood_vessel0.77046166
78MP0002115_abnormal_skeleton_extremities0.76036708
79MP0003453_abnormal_keratinocyte_physiol0.74663775
80MP0000230_abnormal_systemic_arterial0.73161341
81MP0005319_abnormal_enzyme/_coenzyme0.70569316
82MP0001764_abnormal_homeostasis0.70426706
83MP0004085_abnormal_heartbeat0.69845738
84MP0005646_abnormal_pituitary_gland0.69274924
85MP0003646_muscle_fatigue0.68941182
86MP0000467_abnormal_esophagus_morphology0.68638698
87MP0001485_abnormal_pinna_reflex0.68230894
88MP0002971_abnormal_brown_adipose0.67650106
89MP0005334_abnormal_fat_pad0.67376052
90MP0006072_abnormal_retinal_apoptosis0.66597492
91MP0004381_abnormal_hair_follicle0.64067300
92MP0001873_stomach_inflammation0.62236259
93MP0002998_abnormal_bone_remodeling0.61052310
94MP0000685_abnormal_immune_system0.60855885
95MP0009115_abnormal_fat_cell0.60444550
96MP0004264_abnormal_extraembryonic_tissu0.58414882
97MP0002233_abnormal_nose_morphology0.58084430
98MP0000049_abnormal_middle_ear0.55624133
99MP0000681_abnormal_thyroid_gland0.55052700
100MP0000767_abnormal_smooth_muscle0.54478947

Predicted human phenotypes

RankGene SetZ-score
1Calf muscle hypertrophy (HP:0008981)8.51730278
2Exercise-induced myalgia (HP:0003738)8.49012812
3Exercise-induced muscle cramps (HP:0003710)7.75312420
4Muscle hypertrophy of the lower extremities (HP:0008968)7.66031160
5Subaortic stenosis (HP:0001682)5.73657273
6Abnormality of the left ventricular outflow tract (HP:0011103)5.73657273
7Hyporeflexia of lower limbs (HP:0002600)5.41781311
8Abnormality of the calf musculature (HP:0001430)5.14644196
9Sudden death (HP:0001699)5.14471954
10Asymmetric septal hypertrophy (HP:0001670)5.09985351
11Reduced antithrombin III activity (HP:0001976)4.69205210
12Muscle stiffness (HP:0003552)4.63640727
13Aortic aneurysm (HP:0004942)4.59037413
14Prolonged QT interval (HP:0001657)4.40934479
15Neck muscle weakness (HP:0000467)4.39725339
16Abnormality of the columella (HP:0009929)4.33012507
17Myotonia (HP:0002486)3.73098181
18Scapular winging (HP:0003691)3.37511718
19Renal cortical cysts (HP:0000803)3.34416052
20Spinal rigidity (HP:0003306)3.30734402
21Turricephaly (HP:0000262)3.17362320
22Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)3.11022975
23Myopathic facies (HP:0002058)3.09044814
24Abnormality of the shoulder girdle musculature (HP:0001435)3.08164726
25Clumsiness (HP:0002312)3.03706616
26Thoracic kyphosis (HP:0002942)2.98756476
27Resting tremor (HP:0002322)2.95526631
28Hypoplasia of the thymus (HP:0000778)2.93707247
29Gowers sign (HP:0003391)2.89967668
30Popliteal pterygium (HP:0009756)2.81149217
31Ventricular fibrillation (HP:0001663)2.80122018
32Weak cry (HP:0001612)2.68955453
33Increased variability in muscle fiber diameter (HP:0003557)2.66848854
34Absent rod-and cone-mediated responses on ERG (HP:0007688)2.66605547
35Distal lower limb muscle weakness (HP:0009053)2.63744018
36Abnormal EKG (HP:0003115)2.62586771
37Ventricular arrhythmia (HP:0004308)2.54440453
38Abnormality of the frontal sinuses (HP:0002687)2.52417234
39Aplasia/Hypoplasia involving the sinuses (HP:0009120)2.50927310
40Easy fatigability (HP:0003388)2.49871303
41EMG: myopathic abnormalities (HP:0003458)2.49840486
42Difficulty walking (HP:0002355)2.47739641
43Centrally nucleated skeletal muscle fibers (HP:0003687)2.46551690
44Proximal amyotrophy (HP:0007126)2.40298932
45Sensory axonal neuropathy (HP:0003390)2.37633984
46Arterial tortuosity (HP:0005116)2.35456685
47Nonprogressive disorder (HP:0003680)2.33171556
48Vascular tortuosity (HP:0004948)2.32615356
49Inability to walk (HP:0002540)2.30244050
50Areflexia of lower limbs (HP:0002522)2.30082036
51Bulbar palsy (HP:0001283)2.28453427
52Skin nodule (HP:0200036)2.26565625
53Aortic dissection (HP:0002647)2.24896532
54Malignant hyperthermia (HP:0002047)2.23980743
55Abnormality of skeletal muscle fiber size (HP:0012084)2.22846846
56Muscular dystrophy (HP:0003560)2.20307930
57Abnormality of DNA repair (HP:0003254)2.18075695
58Steppage gait (HP:0003376)2.15937660
59Right ventricular cardiomyopathy (HP:0011663)2.15279076
60Facial diplegia (HP:0001349)2.14419383
61Rhabdomyolysis (HP:0003201)2.14176852
62Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.13611662
63Aortic regurgitation (HP:0001659)2.10675309
64Type 2 muscle fiber atrophy (HP:0003554)2.07577912
65Muscle fiber inclusion bodies (HP:0100299)2.06924180
66Aplasia cutis congenita (HP:0001057)2.05540772
67Abnormality of the intrinsic pathway (HP:0010989)2.04619502
68Eosinophilia (HP:0001880)2.03594067
69Abnormality of the renal cortex (HP:0011035)2.01559799
70Myoglobinuria (HP:0002913)2.00393273
71Protrusio acetabuli (HP:0003179)1.98879522
72Rimmed vacuoles (HP:0003805)1.97986797
73Fatigable weakness (HP:0003473)1.97148927
74Abnormality of the neuromuscular junction (HP:0003398)1.97148927
75Type 1 muscle fiber predominance (HP:0003803)1.95960980
76Atrial fibrillation (HP:0005110)1.95332610
77High pitched voice (HP:0001620)1.95134362
78Recurrent corneal erosions (HP:0000495)1.94881300
79Diaphragmatic weakness (HP:0009113)1.94161822
80Benign neoplasm of the central nervous system (HP:0100835)1.90733419
81Urinary urgency (HP:0000012)1.90367554
82Muscle fiber splitting (HP:0003555)1.88779203
83Poor head control (HP:0002421)1.87641990
84Lipoatrophy (HP:0100578)1.85982275
85Flat cornea (HP:0007720)1.83690284
86Metatarsus adductus (HP:0001840)1.83624565
87Respiratory insufficiency due to muscle weakness (HP:0002747)1.80351788
88Abnormality of the thoracic spine (HP:0100711)1.78237218
89Thoracolumbar scoliosis (HP:0002944)1.77597538
90Small epiphyses (HP:0010585)1.76998681
91Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.73688246
92Decreased activity of mitochondrial respiratory chain (HP:0008972)1.73688246
93Primary atrial arrhythmia (HP:0001692)1.73463217
94Muscle fiber atrophy (HP:0100295)1.71538190
95Brushfield spots (HP:0001088)1.70302745
96Distal arthrogryposis (HP:0005684)1.69909016
97Spondylolisthesis (HP:0003302)1.68128615
98High anterior hairline (HP:0009890)1.64165551
99Chronic hepatic failure (HP:0100626)1.63440790
100Frequent falls (HP:0002359)1.63434786

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PINK17.62908271
2MARK34.22348755
3MAPKAPK54.00089857
4MUSK3.71616821
5OBSCN3.44716173
6MYLK3.43028262
7LATS13.26955484
8CDK82.62051498
9NEK22.36282181
10MAPKAPK32.18710411
11MOS2.17947585
12TLK12.14807359
13CCNB12.14217588
14NME22.09307399
15STK38L2.05537295
16LATS22.03075095
17EIF2AK31.86939169
18TIE11.79153893
19MELK1.75883856
20ZAK1.72867668
21MAP2K71.55695816
22EEF2K1.34023970
23CSNK1A1L1.33626095
24MAP3K71.18983266
25FRK1.15854159
26PAK21.12919931
27MAPK121.03002739
28CDK31.01429467
29CSNK1G30.99367584
30PKN20.98764491
31PRKG20.98122273
32CLK10.94841443
33MAP3K130.94593291
34TGFBR10.91255262
35GRK10.85262514
36ARAF0.84751676
37CSNK1G20.79370928
38SGK2230.79032540
39SGK4940.79032540
40CDC42BPA0.78471010
41ADRBK20.76741891
42MAP3K100.75219158
43RPS6KB10.70180091
44MAP3K10.69886848
45PIK3CA0.68017808
46PIK3CG0.67345450
47CSNK1G10.67188778
48MAPK150.64944615
49STK380.64472898
50DAPK30.63773879
51CDK90.63633588
52RPS6KA50.63268601
53DMPK0.62515948
54DYRK30.61221016
55BMPR1B0.60813379
56STK30.58160342
57MST1R0.57913957
58GRK50.57429071
59PRKCQ0.55573786
60PAK10.53656085
61ZAP700.53123382
62AKT20.52997458
63PAK60.50579789
64TNK20.49548400
65ILK0.47871722
66PRKACB0.47407107
67TRPM70.45845535
68ROCK10.45629923
69BTK0.44375724
70PHKG20.43894298
71PHKG10.43894298
72SGK20.38857202
73CSNK1D0.38579907
74DDR20.38146103
75MTOR0.37673525
76CDK40.36500006
77EGFR0.35489673
78NLK0.34942572
79CDK140.34638614
80MAP3K50.34441486
81NME10.34083330
82CAMK10.32235650
83CSNK1A10.31599693
84SCYL20.31451351
85FGFR20.28935878
86MARK20.26757410
87PKN10.26233719
88MAPK40.25817591
89ICK0.25407562
90NEK90.25185040
91AURKB0.24978837
92MAP3K90.22781128
93BLK0.20961988
94PDPK10.20780761
95PTK2B0.20352681
96TRIB30.19369410
97TGFBR20.19185563
98CAMK2D0.18373177
99RET0.18071732
100AURKA0.17808074

Predicted pathways (KEGG)

RankGene SetZ-score
1Olfactory transduction_Homo sapiens_hsa047403.16960203
2beta-Alanine metabolism_Homo sapiens_hsa004103.14992717
3Histidine metabolism_Homo sapiens_hsa003402.98218882
4Pyruvate metabolism_Homo sapiens_hsa006202.76237181
5Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.51550722
6Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.37810969
7Glycolysis / Gluconeogenesis_Homo sapiens_hsa000102.33389424
8Pathogenic Escherichia coli infection_Homo sapiens_hsa051302.18052781
9Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.15741991
10Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054102.12142909
11Gap junction_Homo sapiens_hsa045402.10753082
12Dilated cardiomyopathy_Homo sapiens_hsa054142.03297670
13Propanoate metabolism_Homo sapiens_hsa006402.00153963
14Chemical carcinogenesis_Homo sapiens_hsa052042.00089642
15Pentose and glucuronate interconversions_Homo sapiens_hsa000401.98190398
16Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.86702446
17Vascular smooth muscle contraction_Homo sapiens_hsa042701.81467915
18Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.80566907
19Tryptophan metabolism_Homo sapiens_hsa003801.77222435
20Nitrogen metabolism_Homo sapiens_hsa009101.73364422
21Steroid hormone biosynthesis_Homo sapiens_hsa001401.70701421
22Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.67769187
23PPAR signaling pathway_Homo sapiens_hsa033201.62482467
24ABC transporters_Homo sapiens_hsa020101.60633840
25cGMP-PKG signaling pathway_Homo sapiens_hsa040221.59869914
26Renin secretion_Homo sapiens_hsa049241.57149977
27Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.53488290
28Glycerolipid metabolism_Homo sapiens_hsa005611.51913373
29Butanoate metabolism_Homo sapiens_hsa006501.51771911
30Selenocompound metabolism_Homo sapiens_hsa004501.49537211
31Fatty acid degradation_Homo sapiens_hsa000711.47286872
32Arginine and proline metabolism_Homo sapiens_hsa003301.44968785
33Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.43487436
34Oxytocin signaling pathway_Homo sapiens_hsa049211.42307418
35Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.40498669
36Apoptosis_Homo sapiens_hsa042101.34662117
37Systemic lupus erythematosus_Homo sapiens_hsa053221.33019479
38Arginine biosynthesis_Homo sapiens_hsa002201.32653354
39Phenylalanine metabolism_Homo sapiens_hsa003601.22763118
40Circadian rhythm_Homo sapiens_hsa047101.20634312
41Focal adhesion_Homo sapiens_hsa045101.14121573
42Hedgehog signaling pathway_Homo sapiens_hsa043401.10743405
43Glutathione metabolism_Homo sapiens_hsa004801.00726754
44Retinol metabolism_Homo sapiens_hsa008300.98740972
45ECM-receptor interaction_Homo sapiens_hsa045120.93760896
46Glucagon signaling pathway_Homo sapiens_hsa049220.88417426
47Phagosome_Homo sapiens_hsa041450.86211489
48TGF-beta signaling pathway_Homo sapiens_hsa043500.85475960
49Malaria_Homo sapiens_hsa051440.82723033
50Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.81335999
51Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.80861956
52Phototransduction_Homo sapiens_hsa047440.80133037
53Calcium signaling pathway_Homo sapiens_hsa040200.79773012
54Gastric acid secretion_Homo sapiens_hsa049710.79055101
55Taste transduction_Homo sapiens_hsa047420.77883409
56Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.77676477
57Tyrosine metabolism_Homo sapiens_hsa003500.76227149
58Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.76110024
59AMPK signaling pathway_Homo sapiens_hsa041520.74585290
60Salivary secretion_Homo sapiens_hsa049700.73345401
61Regulation of autophagy_Homo sapiens_hsa041400.73093008
62Wnt signaling pathway_Homo sapiens_hsa043100.72312098
63Viral myocarditis_Homo sapiens_hsa054160.70368114
64Glycosaminoglycan degradation_Homo sapiens_hsa005310.68761275
65Mineral absorption_Homo sapiens_hsa049780.68137359
66Aldosterone synthesis and secretion_Homo sapiens_hsa049250.63661077
67Alcoholism_Homo sapiens_hsa050340.63152942
68Lysine degradation_Homo sapiens_hsa003100.59803180
69SNARE interactions in vesicular transport_Homo sapiens_hsa041300.58231196
70Purine metabolism_Homo sapiens_hsa002300.57471103
71Peroxisome_Homo sapiens_hsa041460.56887396
72Cysteine and methionine metabolism_Homo sapiens_hsa002700.53681028
73Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.53174135
74Asthma_Homo sapiens_hsa053100.53119250
75Protein digestion and absorption_Homo sapiens_hsa049740.52982168
76Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.51896903
77Circadian entrainment_Homo sapiens_hsa047130.51408449
78Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.49029348
79Ovarian steroidogenesis_Homo sapiens_hsa049130.46908172
80NF-kappa B signaling pathway_Homo sapiens_hsa040640.46798085
81Vitamin digestion and absorption_Homo sapiens_hsa049770.46725521
82Fructose and mannose metabolism_Homo sapiens_hsa000510.46042159
83Starch and sucrose metabolism_Homo sapiens_hsa005000.44837624
84Adherens junction_Homo sapiens_hsa045200.42697474
85Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.42115775
86Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.41837999
87Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.40869998
88Pertussis_Homo sapiens_hsa051330.40713546
89Insulin resistance_Homo sapiens_hsa049310.38629314
90Arachidonic acid metabolism_Homo sapiens_hsa005900.36695756
91Renin-angiotensin system_Homo sapiens_hsa046140.36180140
92PI3K-Akt signaling pathway_Homo sapiens_hsa041510.34764881
93Melanogenesis_Homo sapiens_hsa049160.33980434
94Hematopoietic cell lineage_Homo sapiens_hsa046400.32414478
95FoxO signaling pathway_Homo sapiens_hsa040680.32036027
96RNA degradation_Homo sapiens_hsa030180.30445764
97Drug metabolism - other enzymes_Homo sapiens_hsa009830.29555572
98Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.28341017
99Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.27594572
100Tight junction_Homo sapiens_hsa045300.27436363

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »