

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | chromatin remodeling at centromere (GO:0031055) | 5.51457091 |
| 2 | CENP-A containing nucleosome assembly (GO:0034080) | 5.20315918 |
| 3 | DNA double-strand break processing (GO:0000729) | 5.07191462 |
| 4 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 4.98418513 |
| 5 | histone exchange (GO:0043486) | 4.76473963 |
| 6 | DNA replication checkpoint (GO:0000076) | 4.76061244 |
| 7 | mitotic metaphase plate congression (GO:0007080) | 4.51917407 |
| 8 | protein localization to kinetochore (GO:0034501) | 4.40133979 |
| 9 | regulation of mitotic spindle checkpoint (GO:1903504) | 4.35033418 |
| 10 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 4.35033418 |
| 11 | DNA replication-independent nucleosome assembly (GO:0006336) | 4.30773613 |
| 12 | DNA replication-independent nucleosome organization (GO:0034724) | 4.30773613 |
| 13 | mitotic G2/M transition checkpoint (GO:0044818) | 4.16832513 |
| 14 | DNA replication-dependent nucleosome assembly (GO:0006335) | 4.14107882 |
| 15 | DNA replication-dependent nucleosome organization (GO:0034723) | 4.14107882 |
| 16 | metaphase plate congression (GO:0051310) | 4.11529065 |
| 17 | anterior/posterior axis specification, embryo (GO:0008595) | 4.07654731 |
| 18 | replication fork processing (GO:0031297) | 4.01564892 |
| 19 | spindle checkpoint (GO:0031577) | 3.94712390 |
| 20 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 3.90403246 |
| 21 | mitotic sister chromatid segregation (GO:0000070) | 3.89897111 |
| 22 | proteasome assembly (GO:0043248) | 3.89006145 |
| 23 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.87509211 |
| 24 | mitotic spindle checkpoint (GO:0071174) | 3.86364469 |
| 25 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 3.84769914 |
| 26 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 3.84769914 |
| 27 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 3.84769914 |
| 28 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 3.84769914 |
| 29 | negative regulation of sister chromatid segregation (GO:0033046) | 3.84769914 |
| 30 | sister chromatid segregation (GO:0000819) | 3.78369251 |
| 31 | negative regulation of chromosome segregation (GO:0051985) | 3.76207280 |
| 32 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.73172246 |
| 33 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 3.71769802 |
| 34 | establishment of integrated proviral latency (GO:0075713) | 3.69321151 |
| 35 | negative regulation of DNA recombination (GO:0045910) | 3.67625936 |
| 36 | kinetochore organization (GO:0051383) | 3.65072828 |
| 37 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.64717378 |
| 38 | DNA ligation (GO:0006266) | 3.64251092 |
| 39 | mitotic recombination (GO:0006312) | 3.64056654 |
| 40 | DNA strand elongation (GO:0022616) | 3.63299320 |
| 41 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.61817490 |
| 42 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.61817490 |
| 43 | mitotic G2 DNA damage checkpoint (GO:0007095) | 3.57684206 |
| 44 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.57604729 |
| 45 | IMP biosynthetic process (GO:0006188) | 3.54770255 |
| 46 | female gonad development (GO:0008585) | 3.53901969 |
| 47 | regulation of centriole replication (GO:0046599) | 3.52389357 |
| 48 | mitotic sister chromatid cohesion (GO:0007064) | 3.49527542 |
| 49 | regulation of helicase activity (GO:0051095) | 3.48778307 |
| 50 | mitotic spindle assembly checkpoint (GO:0007094) | 3.48728924 |
| 51 | cullin deneddylation (GO:0010388) | 3.48609781 |
| 52 | otic vesicle formation (GO:0030916) | 3.45155555 |
| 53 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 3.44402664 |
| 54 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 3.44402664 |
| 55 | spindle assembly checkpoint (GO:0071173) | 3.42477782 |
| 56 | response to X-ray (GO:0010165) | 3.38356002 |
| 57 | telomere maintenance via telomerase (GO:0007004) | 3.37066474 |
| 58 | purine nucleobase biosynthetic process (GO:0009113) | 3.36081631 |
| 59 | kinetochore assembly (GO:0051382) | 3.31871834 |
| 60 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.29898595 |
| 61 | non-recombinational repair (GO:0000726) | 3.29898595 |
| 62 | regulation of sister chromatid segregation (GO:0033045) | 3.29649163 |
| 63 | regulation of mitotic sister chromatid separation (GO:0010965) | 3.29649163 |
| 64 | regulation of mitotic sister chromatid segregation (GO:0033047) | 3.29649163 |
| 65 | ribosome assembly (GO:0042255) | 3.29102197 |
| 66 | establishment of chromosome localization (GO:0051303) | 3.28684004 |
| 67 | telomere maintenance via recombination (GO:0000722) | 3.28583977 |
| 68 | regulation of chromosome segregation (GO:0051983) | 3.25587535 |
| 69 | DNA unwinding involved in DNA replication (GO:0006268) | 3.23060720 |
| 70 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.22902166 |
| 71 | isotype switching (GO:0045190) | 3.22902166 |
| 72 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.22902166 |
| 73 | positive regulation of cardiac muscle cell proliferation (GO:0060045) | 3.20970988 |
| 74 | telomere maintenance via telomere lengthening (GO:0010833) | 3.18476051 |
| 75 | nodal signaling pathway (GO:0038092) | 3.17930400 |
| 76 | intra-S DNA damage checkpoint (GO:0031573) | 3.14582118 |
| 77 | negative regulation of mitosis (GO:0045839) | 3.13789730 |
| 78 | synapsis (GO:0007129) | 3.13090915 |
| 79 | heterochromatin organization (GO:0070828) | 3.10913059 |
| 80 | protein deneddylation (GO:0000338) | 3.10682222 |
| 81 | mitotic nuclear envelope disassembly (GO:0007077) | 3.07004473 |
| 82 | IMP metabolic process (GO:0046040) | 3.06930955 |
| 83 | protein localization to chromosome, centromeric region (GO:0071459) | 3.02924157 |
| 84 | L-serine metabolic process (GO:0006563) | 3.00275815 |
| 85 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.99532877 |
| 86 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.99400806 |
| 87 | centriole replication (GO:0007099) | 2.98275773 |
| 88 | nucleobase biosynthetic process (GO:0046112) | 2.98016327 |
| 89 | DNA strand renaturation (GO:0000733) | 2.97948138 |
| 90 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.96355777 |
| 91 | regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510) | 2.96345861 |
| 92 | RNA-dependent DNA replication (GO:0006278) | 2.95738704 |
| 93 | double-strand break repair via homologous recombination (GO:0000724) | 2.94859907 |
| 94 | DNA damage response, detection of DNA damage (GO:0042769) | 2.94522220 |
| 95 | recombinational repair (GO:0000725) | 2.94513637 |
| 96 | DNA replication initiation (GO:0006270) | 2.93585123 |
| 97 | ATP-dependent chromatin remodeling (GO:0043044) | 2.92517593 |
| 98 | ventricular cardiac muscle cell development (GO:0055015) | 2.88669114 |
| 99 | histone mRNA metabolic process (GO:0008334) | 2.88445301 |
| 100 | negative regulation of nuclear division (GO:0051784) | 2.88399520 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 6.90723938 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.18533247 |
| 3 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 4.13256959 |
| 4 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 3.26979509 |
| 5 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.16490011 |
| 6 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 3.02275515 |
| 7 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.97119351 |
| 8 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.96047063 |
| 9 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.77444084 |
| 10 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.76690407 |
| 11 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.70029930 |
| 12 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.40511527 |
| 13 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.35310014 |
| 14 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.25482532 |
| 15 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.20891252 |
| 16 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.20465834 |
| 17 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 2.07277373 |
| 18 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.99830417 |
| 19 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.94568513 |
| 20 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.91712518 |
| 21 | EWS_26573619_Chip-Seq_HEK293_Human | 1.81542553 |
| 22 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.78997223 |
| 23 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.78404919 |
| 24 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.77241615 |
| 25 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.76444356 |
| 26 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.72100552 |
| 27 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.70225972 |
| 28 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.69841973 |
| 29 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.69540251 |
| 30 | FUS_26573619_Chip-Seq_HEK293_Human | 1.68943117 |
| 31 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.68619857 |
| 32 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.63179323 |
| 33 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.60364222 |
| 34 | P300_19829295_ChIP-Seq_ESCs_Human | 1.60289252 |
| 35 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.58027256 |
| 36 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.57450870 |
| 37 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.57450870 |
| 38 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.57450870 |
| 39 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.54458825 |
| 40 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.54417519 |
| 41 | VDR_22108803_ChIP-Seq_LS180_Human | 1.54260915 |
| 42 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.53317406 |
| 43 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.50792828 |
| 44 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.49061364 |
| 45 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.46772005 |
| 46 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.45402836 |
| 47 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.41568887 |
| 48 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.39385860 |
| 49 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.37909306 |
| 50 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.33848985 |
| 51 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.30390010 |
| 52 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.29687777 |
| 53 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.28365658 |
| 54 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.27888635 |
| 55 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.27879005 |
| 56 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.26529714 |
| 57 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.25923489 |
| 58 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.23892659 |
| 59 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.23812068 |
| 60 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.22327784 |
| 61 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.21414682 |
| 62 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.21209742 |
| 63 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.20464140 |
| 64 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.15779480 |
| 65 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.14918815 |
| 66 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.14897556 |
| 67 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.14683613 |
| 68 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.11182417 |
| 69 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.08537878 |
| 70 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.08401340 |
| 71 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.06059159 |
| 72 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.04344593 |
| 73 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.02854576 |
| 74 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.02255322 |
| 75 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.01644449 |
| 76 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.01558847 |
| 77 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.99344145 |
| 78 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.99242169 |
| 79 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.98040404 |
| 80 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.96491234 |
| 81 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.95740859 |
| 82 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 0.95693361 |
| 83 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.94776461 |
| 84 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.94186939 |
| 85 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.94010182 |
| 86 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.92383615 |
| 87 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.91068069 |
| 88 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 0.90942178 |
| 89 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.89702158 |
| 90 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.89605104 |
| 91 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.88860645 |
| 92 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.88648717 |
| 93 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.87914301 |
| 94 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.86972985 |
| 95 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 0.86542330 |
| 96 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 0.86463619 |
| 97 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 0.86319295 |
| 98 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.86185047 |
| 99 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.85542984 |
| 100 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.85069770 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0010094_abnormal_chromosome_stability | 4.11632666 |
| 2 | MP0003941_abnormal_skin_development | 3.77657367 |
| 3 | MP0003693_abnormal_embryo_hatching | 3.69084656 |
| 4 | MP0002254_reproductive_system_inflammat | 3.67843903 |
| 5 | MP0008058_abnormal_DNA_repair | 3.66714113 |
| 6 | MP0003890_abnormal_embryonic-extraembry | 3.55369879 |
| 7 | MP0008877_abnormal_DNA_methylation | 3.34514384 |
| 8 | MP0008057_abnormal_DNA_replication | 3.29769981 |
| 9 | MP0004957_abnormal_blastocyst_morpholog | 3.28872005 |
| 10 | MP0003111_abnormal_nucleus_morphology | 3.07673873 |
| 11 | MP0006292_abnormal_olfactory_placode | 2.87285621 |
| 12 | MP0008932_abnormal_embryonic_tissue | 2.53345554 |
| 13 | MP0003077_abnormal_cell_cycle | 2.43610405 |
| 14 | MP0008007_abnormal_cellular_replicative | 2.36084925 |
| 15 | MP0003119_abnormal_digestive_system | 2.07560656 |
| 16 | MP0003136_yellow_coat_color | 2.05801357 |
| 17 | MP0001293_anophthalmia | 2.01265491 |
| 18 | MP0003567_abnormal_fetal_cardiomyocyte | 1.99067095 |
| 19 | MP0003718_maternal_effect | 1.97806014 |
| 20 | MP0009672_abnormal_birth_weight | 1.84371421 |
| 21 | MP0003786_premature_aging | 1.78849709 |
| 22 | MP0001188_hyperpigmentation | 1.78054585 |
| 23 | MP0002102_abnormal_ear_morphology | 1.69881340 |
| 24 | MP0010030_abnormal_orbit_morphology | 1.67443907 |
| 25 | MP0003121_genomic_imprinting | 1.63929904 |
| 26 | MP0009697_abnormal_copulation | 1.57822000 |
| 27 | MP0003123_paternal_imprinting | 1.50532543 |
| 28 | MP0002938_white_spotting | 1.46400020 |
| 29 | MP0003195_calcinosis | 1.45167390 |
| 30 | MP0001730_embryonic_growth_arrest | 1.43819983 |
| 31 | MP0004264_abnormal_extraembryonic_tissu | 1.40322866 |
| 32 | MP0003937_abnormal_limbs/digits/tail_de | 1.39519711 |
| 33 | MP0002751_abnormal_autonomic_nervous | 1.36833936 |
| 34 | MP0001672_abnormal_embryogenesis/_devel | 1.35918255 |
| 35 | MP0005380_embryogenesis_phenotype | 1.35918255 |
| 36 | MP0002736_abnormal_nociception_after | 1.35473837 |
| 37 | MP0001177_atelectasis | 1.33790687 |
| 38 | MP0010307_abnormal_tumor_latency | 1.28788531 |
| 39 | MP0002084_abnormal_developmental_patter | 1.28684866 |
| 40 | MP0001697_abnormal_embryo_size | 1.27067075 |
| 41 | MP0004133_heterotaxia | 1.24898182 |
| 42 | MP0003787_abnormal_imprinting | 1.22097732 |
| 43 | MP0000350_abnormal_cell_proliferation | 1.21736658 |
| 44 | MP0002085_abnormal_embryonic_tissue | 1.21128439 |
| 45 | MP0001286_abnormal_eye_development | 1.17950513 |
| 46 | MP0002233_abnormal_nose_morphology | 1.17822137 |
| 47 | MP0009703_decreased_birth_body | 1.16707926 |
| 48 | MP0006035_abnormal_mitochondrial_morpho | 1.15900664 |
| 49 | MP0010352_gastrointestinal_tract_polyps | 1.13223878 |
| 50 | MP0003984_embryonic_growth_retardation | 1.12261823 |
| 51 | MP0008789_abnormal_olfactory_epithelium | 1.12184681 |
| 52 | MP0000516_abnormal_urinary_system | 1.11858816 |
| 53 | MP0005367_renal/urinary_system_phenotyp | 1.11858816 |
| 54 | MP0001529_abnormal_vocalization | 1.11673821 |
| 55 | MP0002088_abnormal_embryonic_growth/wei | 1.11514166 |
| 56 | MP0001485_abnormal_pinna_reflex | 1.05781156 |
| 57 | MP0000647_abnormal_sebaceous_gland | 1.05462563 |
| 58 | MP0002277_abnormal_respiratory_mucosa | 1.04030948 |
| 59 | MP0003137_abnormal_impulse_conducting | 1.03110392 |
| 60 | MP0006072_abnormal_retinal_apoptosis | 1.02806206 |
| 61 | MP0000372_irregular_coat_pigmentation | 1.02784329 |
| 62 | MP0002080_prenatal_lethality | 0.99060984 |
| 63 | MP0002210_abnormal_sex_determination | 0.96518967 |
| 64 | MP0000579_abnormal_nail_morphology | 0.96341622 |
| 65 | MP0008004_abnormal_stomach_pH | 0.96327662 |
| 66 | MP0001929_abnormal_gametogenesis | 0.95793670 |
| 67 | MP0002697_abnormal_eye_size | 0.95455607 |
| 68 | MP0002234_abnormal_pharynx_morphology | 0.91100978 |
| 69 | MP0004215_abnormal_myocardial_fiber | 0.89760840 |
| 70 | MP0003122_maternal_imprinting | 0.89554053 |
| 71 | MP0004197_abnormal_fetal_growth/weight/ | 0.89406865 |
| 72 | MP0003806_abnormal_nucleotide_metabolis | 0.87931397 |
| 73 | MP0005084_abnormal_gallbladder_morpholo | 0.87666889 |
| 74 | MP0003880_abnormal_central_pattern | 0.87665524 |
| 75 | MP0005394_taste/olfaction_phenotype | 0.85091731 |
| 76 | MP0005499_abnormal_olfactory_system | 0.85091731 |
| 77 | MP0003186_abnormal_redox_activity | 0.83955652 |
| 78 | MP0005551_abnormal_eye_electrophysiolog | 0.83305408 |
| 79 | MP0001299_abnormal_eye_distance/ | 0.83105630 |
| 80 | MP0000653_abnormal_sex_gland | 0.81771987 |
| 81 | MP0001145_abnormal_male_reproductive | 0.81657667 |
| 82 | MP0002086_abnormal_extraembryonic_tissu | 0.80990758 |
| 83 | MP0002111_abnormal_tail_morphology | 0.80606297 |
| 84 | MP0000313_abnormal_cell_death | 0.80549170 |
| 85 | MP0000427_abnormal_hair_cycle | 0.79381069 |
| 86 | MP0006054_spinal_hemorrhage | 0.79335244 |
| 87 | MP0003943_abnormal_hepatobiliary_system | 0.78082651 |
| 88 | MP0002090_abnormal_vision | 0.77155373 |
| 89 | MP0005253_abnormal_eye_physiology | 0.75544690 |
| 90 | MP0005075_abnormal_melanosome_morpholog | 0.73515422 |
| 91 | MP0000428_abnormal_craniofacial_morphol | 0.72360991 |
| 92 | MP0003283_abnormal_digestive_organ | 0.70710766 |
| 93 | MP0001119_abnormal_female_reproductive | 0.70530216 |
| 94 | MP0003011_delayed_dark_adaptation | 0.65905896 |
| 95 | MP0004147_increased_porphyrin_level | 0.65226798 |
| 96 | MP0005395_other_phenotype | 0.64892009 |
| 97 | MP0000049_abnormal_middle_ear | 0.64885719 |
| 98 | MP0003936_abnormal_reproductive_system | 0.64616288 |
| 99 | MP0005391_vision/eye_phenotype | 0.64474752 |
| 100 | MP0003861_abnormal_nervous_system | 0.64430653 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of the labia minora (HP:0012880) | 5.17609979 |
| 2 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 3.99941189 |
| 3 | Chromsome breakage (HP:0040012) | 3.92736057 |
| 4 | Abnormality of chromosome stability (HP:0003220) | 3.87547704 |
| 5 | Meckel diverticulum (HP:0002245) | 3.78375434 |
| 6 | Abnormality of the ileum (HP:0001549) | 3.64328603 |
| 7 | Progressive inability to walk (HP:0002505) | 3.64113074 |
| 8 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 3.52498408 |
| 9 | Colon cancer (HP:0003003) | 3.43937821 |
| 10 | Birth length less than 3rd percentile (HP:0003561) | 3.43405140 |
| 11 | Abnormality of the preputium (HP:0100587) | 3.27876446 |
| 12 | Intestinal atresia (HP:0011100) | 3.27731895 |
| 13 | Abnormality of the duodenum (HP:0002246) | 3.19093302 |
| 14 | Pancreatic islet-cell hyperplasia (HP:0004510) | 3.13145345 |
| 15 | Duodenal stenosis (HP:0100867) | 3.10718799 |
| 16 | Small intestinal stenosis (HP:0012848) | 3.10718799 |
| 17 | Ependymoma (HP:0002888) | 3.10183047 |
| 18 | Volvulus (HP:0002580) | 3.09318391 |
| 19 | Septo-optic dysplasia (HP:0100842) | 2.90487511 |
| 20 | Abnormality of the parathyroid morphology (HP:0011766) | 2.88216679 |
| 21 | Abnormal lung lobation (HP:0002101) | 2.85948684 |
| 22 | Aqueductal stenosis (HP:0002410) | 2.78479518 |
| 23 | Embryonal renal neoplasm (HP:0011794) | 2.70815428 |
| 24 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.69179369 |
| 25 | Absent radius (HP:0003974) | 2.66266214 |
| 26 | Methylmalonic acidemia (HP:0002912) | 2.50786516 |
| 27 | Absent forearm bone (HP:0003953) | 2.50672289 |
| 28 | Aplasia involving forearm bones (HP:0009822) | 2.50672289 |
| 29 | Multiple enchondromatosis (HP:0005701) | 2.50072771 |
| 30 | Abnormality of the fetal cardiovascular system (HP:0010948) | 2.44612272 |
| 31 | Abnormal umbilical cord blood vessels (HP:0011403) | 2.44612272 |
| 32 | Single umbilical artery (HP:0001195) | 2.44612272 |
| 33 | Abnormality of serum amino acid levels (HP:0003112) | 2.43114482 |
| 34 | Sloping forehead (HP:0000340) | 2.41750733 |
| 35 | Abnormality of alanine metabolism (HP:0010916) | 2.39048105 |
| 36 | Hyperalaninemia (HP:0003348) | 2.39048105 |
| 37 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.39048105 |
| 38 | Neoplasm of the adrenal gland (HP:0100631) | 2.37487417 |
| 39 | Triphalangeal thumb (HP:0001199) | 2.35788287 |
| 40 | Double outlet right ventricle (HP:0001719) | 2.35326263 |
| 41 | Congenital malformation of the right heart (HP:0011723) | 2.35326263 |
| 42 | Rhabdomyosarcoma (HP:0002859) | 2.33694186 |
| 43 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.32896097 |
| 44 | Abnormality of methionine metabolism (HP:0010901) | 2.32497832 |
| 45 | Neoplasm of the oral cavity (HP:0100649) | 2.31864910 |
| 46 | Oligodactyly (hands) (HP:0001180) | 2.31674440 |
| 47 | Clubbing of toes (HP:0100760) | 2.30920116 |
| 48 | Glioma (HP:0009733) | 2.28790106 |
| 49 | Agnosia (HP:0010524) | 2.22063913 |
| 50 | Abnormal hair whorl (HP:0010721) | 2.21501031 |
| 51 | Esophageal atresia (HP:0002032) | 2.15846548 |
| 52 | Absent septum pellucidum (HP:0001331) | 2.14881083 |
| 53 | Medulloblastoma (HP:0002885) | 2.12692969 |
| 54 | Bifid tongue (HP:0010297) | 2.11474946 |
| 55 | Carpal bone hypoplasia (HP:0001498) | 2.07985383 |
| 56 | Abnormality of the carotid arteries (HP:0005344) | 2.07602060 |
| 57 | Horseshoe kidney (HP:0000085) | 2.07481997 |
| 58 | Inability to walk (HP:0002540) | 2.07044116 |
| 59 | Hypoglycemic seizures (HP:0002173) | 2.06298797 |
| 60 | Hyperglycinuria (HP:0003108) | 2.05569796 |
| 61 | Gastrointestinal atresia (HP:0002589) | 2.02676877 |
| 62 | Stenosis of the external auditory canal (HP:0000402) | 2.00138472 |
| 63 | Ectopic kidney (HP:0000086) | 2.00009686 |
| 64 | Hypoplastic female external genitalia (HP:0012815) | 1.99359311 |
| 65 | Abnormality of homocysteine metabolism (HP:0010919) | 1.99220757 |
| 66 | Homocystinuria (HP:0002156) | 1.99220757 |
| 67 | Pancreatic cysts (HP:0001737) | 1.98126670 |
| 68 | Astrocytoma (HP:0009592) | 1.96601439 |
| 69 | Abnormality of the astrocytes (HP:0100707) | 1.96601439 |
| 70 | Labial hypoplasia (HP:0000066) | 1.94763906 |
| 71 | Hyperglycinemia (HP:0002154) | 1.94604339 |
| 72 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.94206360 |
| 73 | Abnormality of glycine metabolism (HP:0010895) | 1.94206360 |
| 74 | Abnormality of the septum pellucidum (HP:0007375) | 1.93545716 |
| 75 | Abnormal pancreas size (HP:0012094) | 1.93281280 |
| 76 | Methylmalonic aciduria (HP:0012120) | 1.92899043 |
| 77 | Abnormality of the clitoris (HP:0000056) | 1.92151015 |
| 78 | Symptomatic seizures (HP:0011145) | 1.91389995 |
| 79 | Small hand (HP:0200055) | 1.91031669 |
| 80 | Abnormality of endocrine pancreas physiology (HP:0012093) | 1.89650364 |
| 81 | Abnormality of the pancreatic islet cells (HP:0006476) | 1.89650364 |
| 82 | Abnormality of the umbilical cord (HP:0010881) | 1.88125760 |
| 83 | Ovarian neoplasm (HP:0100615) | 1.87466408 |
| 84 | Anophthalmia (HP:0000528) | 1.84021201 |
| 85 | Choanal atresia (HP:0000453) | 1.83628794 |
| 86 | Hypoplasia of the pons (HP:0012110) | 1.81042021 |
| 87 | Abnormality of the labia (HP:0000058) | 1.77900420 |
| 88 | Myelodysplasia (HP:0002863) | 1.77298981 |
| 89 | Abnormality of the pons (HP:0007361) | 1.76469568 |
| 90 | Gonadotropin excess (HP:0000837) | 1.76350098 |
| 91 | Abolished electroretinogram (ERG) (HP:0000550) | 1.75506483 |
| 92 | Anal stenosis (HP:0002025) | 1.72281408 |
| 93 | Growth hormone deficiency (HP:0000824) | 1.71149429 |
| 94 | Breast carcinoma (HP:0003002) | 1.70971849 |
| 95 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.70921531 |
| 96 | Preaxial hand polydactyly (HP:0001177) | 1.70458376 |
| 97 | Biliary tract neoplasm (HP:0100574) | 1.68923253 |
| 98 | True hermaphroditism (HP:0010459) | 1.68904530 |
| 99 | Vaginal atresia (HP:0000148) | 1.68527875 |
| 100 | Astigmatism (HP:0000483) | 1.68187644 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TRIM28 | 3.67106059 |
| 2 | BUB1 | 3.65296425 |
| 3 | ERBB4 | 3.31018512 |
| 4 | ACVR1B | 3.28071030 |
| 5 | TSSK6 | 3.27998109 |
| 6 | PBK | 3.24824034 |
| 7 | PDK2 | 3.19149309 |
| 8 | MKNK2 | 3.16262909 |
| 9 | TNIK | 3.00764425 |
| 10 | TTK | 2.99132365 |
| 11 | WNK3 | 2.77181789 |
| 12 | BMPR1B | 2.68121270 |
| 13 | PLK3 | 2.52317071 |
| 14 | NEK1 | 2.44715548 |
| 15 | MKNK1 | 2.41098947 |
| 16 | CDC7 | 2.32692702 |
| 17 | PLK4 | 2.29775731 |
| 18 | WEE1 | 2.27914954 |
| 19 | ZAK | 2.26245358 |
| 20 | MST4 | 2.17897950 |
| 21 | EIF2AK3 | 2.16912417 |
| 22 | NUAK1 | 1.78087596 |
| 23 | BRSK2 | 1.77118515 |
| 24 | SRPK1 | 1.74744464 |
| 25 | TGFBR1 | 1.55233382 |
| 26 | PLK1 | 1.53951061 |
| 27 | VRK1 | 1.49505830 |
| 28 | VRK2 | 1.35510498 |
| 29 | SIK3 | 1.33706960 |
| 30 | STK16 | 1.33591958 |
| 31 | FRK | 1.32589249 |
| 32 | PNCK | 1.31395642 |
| 33 | EIF2AK2 | 1.23630635 |
| 34 | MAP4K2 | 1.20326868 |
| 35 | TAF1 | 1.11438183 |
| 36 | ERBB3 | 1.05846422 |
| 37 | BCR | 1.03586144 |
| 38 | ATR | 1.02545047 |
| 39 | GRK1 | 1.01671274 |
| 40 | NEK2 | 1.00483320 |
| 41 | NLK | 0.96286279 |
| 42 | STK3 | 0.89812623 |
| 43 | EIF2AK1 | 0.88242269 |
| 44 | OXSR1 | 0.85365219 |
| 45 | CHEK2 | 0.81733310 |
| 46 | BRSK1 | 0.80813094 |
| 47 | PASK | 0.78046433 |
| 48 | PLK2 | 0.71575967 |
| 49 | ATM | 0.70775473 |
| 50 | STK4 | 0.68292863 |
| 51 | MELK | 0.68287465 |
| 52 | CHEK1 | 0.67972645 |
| 53 | AURKB | 0.66626704 |
| 54 | MAPK13 | 0.64768218 |
| 55 | CASK | 0.64679729 |
| 56 | STK39 | 0.59590849 |
| 57 | FGFR1 | 0.56948692 |
| 58 | STK38L | 0.56692804 |
| 59 | ALK | 0.55514454 |
| 60 | PRKCG | 0.51677001 |
| 61 | FGFR2 | 0.47965893 |
| 62 | CSNK1G1 | 0.47164621 |
| 63 | DYRK2 | 0.43683681 |
| 64 | DAPK1 | 0.43124313 |
| 65 | CSNK2A1 | 0.40022247 |
| 66 | MINK1 | 0.39431583 |
| 67 | RPS6KA4 | 0.39155233 |
| 68 | INSRR | 0.38899014 |
| 69 | CDK7 | 0.38708975 |
| 70 | PRKDC | 0.37285106 |
| 71 | FLT3 | 0.36501839 |
| 72 | NME1 | 0.35951887 |
| 73 | DYRK3 | 0.35386525 |
| 74 | CDK19 | 0.33780674 |
| 75 | PAK3 | 0.33342470 |
| 76 | CDK1 | 0.33175938 |
| 77 | MAP3K10 | 0.31996773 |
| 78 | MAP3K8 | 0.31745030 |
| 79 | PRKCE | 0.29923959 |
| 80 | BRAF | 0.29854174 |
| 81 | PINK1 | 0.29752232 |
| 82 | CSNK1E | 0.29565800 |
| 83 | CSNK2A2 | 0.29011194 |
| 84 | TIE1 | 0.27767756 |
| 85 | CSNK1G2 | 0.26772566 |
| 86 | PKN1 | 0.24698364 |
| 87 | CDK2 | 0.24357988 |
| 88 | CDK3 | 0.24245180 |
| 89 | STK10 | 0.22567982 |
| 90 | CLK1 | 0.21847007 |
| 91 | CSNK1D | 0.21515172 |
| 92 | CSNK1G3 | 0.18642184 |
| 93 | YES1 | 0.18015366 |
| 94 | FGR | 0.17117987 |
| 95 | CDK4 | 0.16747042 |
| 96 | PRKACB | 0.16626534 |
| 97 | BRD4 | 0.16455431 |
| 98 | PRKCI | 0.16272314 |
| 99 | CSNK1A1 | 0.15812229 |
| 100 | LATS1 | 0.14755675 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Mismatch repair_Homo sapiens_hsa03430 | 3.89688912 |
| 2 | Non-homologous end-joining_Homo sapiens_hsa03450 | 3.67449848 |
| 3 | Homologous recombination_Homo sapiens_hsa03440 | 3.41464829 |
| 4 | DNA replication_Homo sapiens_hsa03030 | 3.40174264 |
| 5 | Proteasome_Homo sapiens_hsa03050 | 3.27939830 |
| 6 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.82514852 |
| 7 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.68938350 |
| 8 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.30014737 |
| 9 | RNA transport_Homo sapiens_hsa03013 | 2.20455224 |
| 10 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.19067357 |
| 11 | Base excision repair_Homo sapiens_hsa03410 | 2.15308293 |
| 12 | Cell cycle_Homo sapiens_hsa04110 | 2.13933800 |
| 13 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 2.09308415 |
| 14 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 2.07545825 |
| 15 | RNA polymerase_Homo sapiens_hsa03020 | 2.00492309 |
| 16 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.97252320 |
| 17 | Protein export_Homo sapiens_hsa03060 | 1.96289649 |
| 18 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.95875112 |
| 19 | RNA degradation_Homo sapiens_hsa03018 | 1.89310245 |
| 20 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.88745508 |
| 21 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.86899030 |
| 22 | Basal transcription factors_Homo sapiens_hsa03022 | 1.86286324 |
| 23 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.85781355 |
| 24 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.82352049 |
| 25 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.81285004 |
| 26 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.71745154 |
| 27 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.69889016 |
| 28 | Spliceosome_Homo sapiens_hsa03040 | 1.65376175 |
| 29 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.51718263 |
| 30 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.44079953 |
| 31 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.43166394 |
| 32 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.38160474 |
| 33 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.31856285 |
| 34 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.21302855 |
| 35 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.19352682 |
| 36 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.19037358 |
| 37 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.11246935 |
| 38 | Carbon metabolism_Homo sapiens_hsa01200 | 1.02748734 |
| 39 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.01994354 |
| 40 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.01928532 |
| 41 | Purine metabolism_Homo sapiens_hsa00230 | 1.00018189 |
| 42 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.92297202 |
| 43 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.88302719 |
| 44 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.86709075 |
| 45 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.86177507 |
| 46 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.85919803 |
| 47 | Phototransduction_Homo sapiens_hsa04744 | 0.85573990 |
| 48 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.84981678 |
| 49 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.84926405 |
| 50 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.82263573 |
| 51 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.80960003 |
| 52 | Peroxisome_Homo sapiens_hsa04146 | 0.76517788 |
| 53 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.76245666 |
| 54 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.75870174 |
| 55 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.75673725 |
| 56 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.68825291 |
| 57 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.68668978 |
| 58 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.66137196 |
| 59 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.64951831 |
| 60 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.63988455 |
| 61 | Retinol metabolism_Homo sapiens_hsa00830 | 0.63348576 |
| 62 | Parkinsons disease_Homo sapiens_hsa05012 | 0.61988558 |
| 63 | Huntingtons disease_Homo sapiens_hsa05016 | 0.58933698 |
| 64 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.58523213 |
| 65 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.57796253 |
| 66 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.57245227 |
| 67 | Metabolic pathways_Homo sapiens_hsa01100 | 0.55883670 |
| 68 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.55455384 |
| 69 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.53301047 |
| 70 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.52550818 |
| 71 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.52370856 |
| 72 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.51525527 |
| 73 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.51498070 |
| 74 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.49873019 |
| 75 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.47965824 |
| 76 | Lysine degradation_Homo sapiens_hsa00310 | 0.47412735 |
| 77 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.45940939 |
| 78 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.45747190 |
| 79 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.44225548 |
| 80 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.44159118 |
| 81 | Tight junction_Homo sapiens_hsa04530 | 0.43884063 |
| 82 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.40353817 |
| 83 | Olfactory transduction_Homo sapiens_hsa04740 | 0.39159838 |
| 84 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.35298516 |
| 85 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.34578004 |
| 86 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.33364264 |
| 87 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.33314831 |
| 88 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.32568839 |
| 89 | Adherens junction_Homo sapiens_hsa04520 | 0.27077598 |
| 90 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.25973111 |
| 91 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.25520527 |
| 92 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.25278871 |
| 93 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.24604451 |
| 94 | Nicotine addiction_Homo sapiens_hsa05033 | 0.23431740 |
| 95 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.22055561 |
| 96 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.19409861 |
| 97 | Legionellosis_Homo sapiens_hsa05134 | 0.17098769 |
| 98 | Histidine metabolism_Homo sapiens_hsa00340 | 0.16547269 |
| 99 | Alzheimers disease_Homo sapiens_hsa05010 | 0.13557977 |
| 100 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.13514590 |

