BORCS6

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.25713105
2antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.25713105
3antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.09540327
4antigen processing and presentation of endogenous antigen (GO:0019883)3.89560946
5detection of bacterium (GO:0016045)3.83182619
6detection of other organism (GO:0098543)3.80246930
7regulation of mast cell degranulation (GO:0043304)3.72614710
8negative regulation of erythrocyte differentiation (GO:0045647)3.54223042
9positive regulation of gamma-delta T cell activation (GO:0046645)3.52103209
10negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)3.44158568
11neutrophil activation (GO:0042119)3.39913915
12regulation of mast cell activation involved in immune response (GO:0033006)3.33329384
13negative regulation of interleukin-12 production (GO:0032695)3.29219770
14regulation of myeloid leukocyte mediated immunity (GO:0002886)3.28512906
15regulation of leukocyte degranulation (GO:0043300)3.26744877
16granulocyte activation (GO:0036230)3.24104746
17positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.22698749
18respiratory burst (GO:0045730)3.15569768
19neutrophil activation involved in immune response (GO:0002283)3.13646513
20mannose metabolic process (GO:0006013)3.12980669
21sodium ion export (GO:0071436)3.10600028
22detection of external biotic stimulus (GO:0098581)3.08614270
23antigen processing and presentation via MHC class Ib (GO:0002475)3.07743701
24modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.04398845
25positive regulation by organism of defense response of other organism involved in symbiotic interact3.04398845
26modulation by symbiont of host immune response (GO:0052553)3.04398845
27positive regulation by symbiont of host defense response (GO:0052509)3.04398845
28modulation by symbiont of host defense response (GO:0052031)3.04398845
29modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.04398845
30negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.04361962
31negative regulation of cell killing (GO:0031342)3.04361962
32positive thymic T cell selection (GO:0045059)3.03842310
33negative regulation of innate immune response (GO:0045824)3.02020627
34response to muramyl dipeptide (GO:0032495)2.97518013
35G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.97416165
36negative regulation of lymphocyte mediated immunity (GO:0002707)2.95738266
37adenosine receptor signaling pathway (GO:0001973)2.94238107
38macrophage activation involved in immune response (GO:0002281)2.93724800
39deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.93169254
40leukocyte migration involved in inflammatory response (GO:0002523)2.92280453
41regulation of mast cell activation (GO:0033003)2.92065119
42G-protein coupled purinergic receptor signaling pathway (GO:0035588)2.91811360
43negative regulation of leukocyte mediated immunity (GO:0002704)2.89963142
44positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.88748116
45negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.86997500
46regulation of interferon-beta biosynthetic process (GO:0045357)2.85210306
47lipoxygenase pathway (GO:0019372)2.84651345
48positive regulation of B cell differentiation (GO:0045579)2.78944951
49B cell mediated immunity (GO:0019724)2.77887621
50modulation by virus of host process (GO:0019054)2.77431701
51germinal center formation (GO:0002467)2.74148100
52cellular potassium ion homeostasis (GO:0030007)2.73628978
53detection of biotic stimulus (GO:0009595)2.71048453
54regulation of gamma-delta T cell differentiation (GO:0045586)2.69520765
55regulation of T-helper 2 cell differentiation (GO:0045628)2.67195053
56negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.65549574
57regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.63944336
58regulation of natural killer cell mediated immunity (GO:0002715)2.63944336
59negative thymic T cell selection (GO:0045060)2.63402933
60regulation of superoxide anion generation (GO:0032928)2.63231414
61regulation of B cell receptor signaling pathway (GO:0050855)2.63201797
62regulation of regulated secretory pathway (GO:1903305)2.62747863
63type I interferon signaling pathway (GO:0060337)2.61009056
64cellular response to type I interferon (GO:0071357)2.61009056
65disruption of cells of other organism involved in symbiotic interaction (GO:0051818)2.60556410
66killing of cells in other organism involved in symbiotic interaction (GO:0051883)2.60556410
67modulation by symbiont of host cellular process (GO:0044068)2.60256738
68regulation of gamma-delta T cell activation (GO:0046643)2.59461478
69positive regulation of natural killer cell differentiation (GO:0032825)2.59151830
70positive regulation of mast cell degranulation (GO:0043306)2.58058549
71positive regulation of mast cell activation involved in immune response (GO:0033008)2.58058549
72response to type I interferon (GO:0034340)2.57965612
73defense response to protozoan (GO:0042832)2.57581035
74amyloid precursor protein catabolic process (GO:0042987)2.56473805
75synaptic vesicle maturation (GO:0016188)2.56172219
76negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.55922337
77thymic T cell selection (GO:0045061)2.55518725
78negative regulation of cytokine production involved in immune response (GO:0002719)2.55390558
79positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.54622544
80negative regulation of T cell mediated immunity (GO:0002710)2.53670686
81purine deoxyribonucleotide catabolic process (GO:0009155)2.52789548
82leukocyte aggregation (GO:0070486)2.51161169
83positive regulation of lamellipodium assembly (GO:0010592)2.50935120
84Arp2/3 complex-mediated actin nucleation (GO:0034314)2.50226038
85regulation of early endosome to late endosome transport (GO:2000641)2.49883474
86neutrophil mediated immunity (GO:0002446)2.49583285
87pentose-phosphate shunt (GO:0006098)2.49283661
88detection of molecule of bacterial origin (GO:0032490)2.48682420
89detection of temperature stimulus involved in sensory perception (GO:0050961)2.47344165
90detection of temperature stimulus involved in sensory perception of pain (GO:0050965)2.47344165
91positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)2.46225396
92tolerance induction (GO:0002507)2.45561622
93myeloid cell activation involved in immune response (GO:0002275)2.44749598
94regulation of platelet aggregation (GO:0090330)2.44375023
95regulation of T cell mediated cytotoxicity (GO:0001914)2.43777327
96JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.43460378
97pinocytosis (GO:0006907)2.43182454
98negative T cell selection (GO:0043383)2.43178867
99regulation of ARF protein signal transduction (GO:0032012)2.42620070
100positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.41759502
101low-density lipoprotein particle clearance (GO:0034383)2.41471260
102positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.41117951
103cellular extravasation (GO:0045123)2.39267725
104negative regulation of interleukin-17 production (GO:0032700)2.39014011
105cellular response to zinc ion (GO:0071294)2.36333820
106natural killer cell differentiation (GO:0001779)2.36063892
107immunoglobulin mediated immune response (GO:0016064)2.35114739
108NIK/NF-kappaB signaling (GO:0038061)2.33758654
109positive regulation of p38MAPK cascade (GO:1900745)2.30651783
110response to protozoan (GO:0001562)2.29503019
111regulation of B cell differentiation (GO:0045577)2.28371990
112barbed-end actin filament capping (GO:0051016)2.27215128
113mature B cell differentiation (GO:0002335)2.25821986
114lipopolysaccharide-mediated signaling pathway (GO:0031663)2.23152008
115response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.23071059
116response to host (GO:0075136)2.23071059
117response to host defenses (GO:0052200)2.23071059
118regulation of natural killer cell differentiation (GO:0032823)2.22146339
119synaptic vesicle exocytosis (GO:0016079)2.22091256
120response to host immune response (GO:0052572)2.21335665
121response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.21335665
122activation of MAPKKK activity (GO:0000185)2.21281416
123oxaloacetate metabolic process (GO:0006107)2.20415518
124G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.18979632
125negative regulation of myeloid cell apoptotic process (GO:0033033)2.17457298
126response to nerve growth factor (GO:1990089)2.15572255
127cellular response to nerve growth factor stimulus (GO:1990090)2.15572255
128actin filament polymerization (GO:0030041)2.14835750
129NADPH regeneration (GO:0006740)2.14649948
130response to peptidoglycan (GO:0032494)2.14464337
131leukocyte degranulation (GO:0043299)2.12907636
132positive regulation of antigen processing and presentation (GO:0002579)2.12108405
133regulation of synaptic vesicle transport (GO:1902803)2.10057482
134creatine metabolic process (GO:0006600)2.09532388
135leukocyte mediated cytotoxicity (GO:0001909)2.08045844
136positive regulation of mast cell activation (GO:0033005)2.06821729
137regulation of dendritic cell antigen processing and presentation (GO:0002604)2.06443830
138mature B cell differentiation involved in immune response (GO:0002313)2.05718038
139phagosome maturation (GO:0090382)2.05703419
140positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.05537734
141regulation of synapse structural plasticity (GO:0051823)2.04914526
142response to acidic pH (GO:0010447)2.04178316
143regulation of synaptic vesicle exocytosis (GO:2000300)2.03906770
144negative regulation of type 2 immune response (GO:0002829)2.03748854
145myeloid dendritic cell differentiation (GO:0043011)2.03478527
146Peyers patch development (GO:0048541)2.02922153
147mucosal-associated lymphoid tissue development (GO:0048537)2.02922153
148interferon-gamma-mediated signaling pathway (GO:0060333)2.02507931
149regulation of chemokine biosynthetic process (GO:0045073)2.02185374
150B cell receptor signaling pathway (GO:0050853)2.02094898
151regulation of ARF GTPase activity (GO:0032312)2.01598611
152mast cell activation (GO:0045576)2.01597663
153myeloid leukocyte mediated immunity (GO:0002444)2.01336312
154regulation of interleukin-12 biosynthetic process (GO:0045075)2.01287577

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_21731497_ChIP-ChIP_J774_Mouse2.63773726
2MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.60297382
3PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.41947254
4NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.39494032
5THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.38410447
6IRF8_22096565_ChIP-ChIP_GC-B_Human2.38196758
7MYB_21317192_ChIP-Seq_ERMYB_Mouse2.33764465
8KDM2B_26808549_Chip-Seq_SUP-B15_Human2.33007419
9VDR_21846776_ChIP-Seq_THP-1_Human2.29831367
10MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.28344426
11RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.26616973
12BP1_19119308_ChIP-ChIP_Hs578T_Human2.24796212
13LXR_22292898_ChIP-Seq_THP-1_Human2.22254660
14STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.20020710
15SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.19743309
16NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.12573058
17KDM2B_26808549_Chip-Seq_DND41_Human2.11958609
18IRF8_27001747_Chip-Seq_BMDM_Mouse2.10792166
19NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.08436452
20TCF7_22412390_ChIP-Seq_EML_Mouse2.02073940
21ELK3_25401928_ChIP-Seq_HUVEC_Human2.01867564
22MAF_26560356_Chip-Seq_TH1_Human1.91499781
23ELF1_17652178_ChIP-ChIP_JURKAT_Human1.88769482
24SPI1_23127762_ChIP-Seq_K562_Human1.88657030
25ZNF263_19887448_ChIP-Seq_K562_Human1.87870233
26KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.87059873
27E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.86752939
28ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.85901853
29VDR_24763502_ChIP-Seq_THP-1_Human1.82050670
30EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.81940380
31BRD4_27068464_Chip-Seq_AML-cells_Mouse1.79990828
32TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.79114556
33SCL_19346495_ChIP-Seq_HPC-7_Human1.75117415
34FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.74090371
35SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.66563965
36IKZF1_21737484_ChIP-ChIP_HCT116_Human1.65964508
37TET1_21451524_ChIP-Seq_MESCs_Mouse1.62238162
38MYC_22102868_ChIP-Seq_BL_Human1.59177515
39RARG_19884340_ChIP-ChIP_MEFs_Mouse1.57800242
40TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.53927461
41KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.52837823
42RUNX1_22412390_ChIP-Seq_EML_Mouse1.49932207
43GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.48446884
44RACK7_27058665_Chip-Seq_MCF-7_Human1.48052462
45GATA1_19941827_ChIP-Seq_MEL_Mouse1.47946929
46RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.47932843
47TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.45932277
48GATA1_19941826_ChIP-Seq_K562_Human1.44904146
49LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.44170269
50SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.43950531
51KDM2B_26808549_Chip-Seq_K562_Human1.42322887
52TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.41225638
53MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.40136271
54CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.39605292
55UTX_26944678_Chip-Seq_JUKART_Human1.38488420
56PU.1_20513432_ChIP-Seq_Bcells_Mouse1.38294455
57Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.34859569
58GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.34648430
59RXR_22158963_ChIP-Seq_LIVER_Mouse1.33377158
60MAF_26560356_Chip-Seq_TH2_Human1.32955413
61IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.32424668
62IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.32408921
63HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.32336685
64SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.32146967
65CTCF_27219007_Chip-Seq_ERYTHROID_Human1.31272672
66EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.30754328
67BCL6_27268052_Chip-Seq_Bcells_Human1.30478050
68RUNX_20019798_ChIP-Seq_JUKART_Human1.30293789
69EGR1_19374776_ChIP-ChIP_THP-1_Human1.30150473
70GATA2_22383799_ChIP-Seq_G1ME_Mouse1.29071204
71CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.28956097
72NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.28922143
73PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.27551771
74NCOR1_26117541_ChIP-Seq_K562_Human1.26976119
75PPARA_22158963_ChIP-Seq_LIVER_Mouse1.26896205
76EZH2_22144423_ChIP-Seq_EOC_Human1.26521714
77EGR1_19032775_ChIP-ChIP_M12_Human1.26302913
78BCOR_27268052_Chip-Seq_Bcells_Human1.26027986
79ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.25788094
80SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.25570050
81KDM2B_26808549_Chip-Seq_JURKAT_Human1.25449450
82TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.25202790
83DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.25170345
84GATA2_21666600_ChIP-Seq_HMVEC_Human1.24451158
85STAT4_19710469_ChIP-ChIP_TH1__Mouse1.24426727
86DNAJC2_21179169_ChIP-ChIP_NT2_Human1.24118774
87SRY_22984422_ChIP-ChIP_TESTIS_Rat1.23788933
88FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.23617020
89LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.23341138
90SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.22859284
91MYB_26560356_Chip-Seq_TH1_Human1.22505290
92ELF1_20517297_ChIP-Seq_JURKAT_Human1.21283246
93MYB_26560356_Chip-Seq_TH2_Human1.19993762
94CTCF_26484167_Chip-Seq_Bcells_Mouse1.19727586
95ESR2_21235772_ChIP-Seq_MCF-7_Human1.19629523
96SPI1_20517297_ChIP-Seq_HL60_Human1.19002030
97SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.18205451
98GATA2_19941826_ChIP-Seq_K562_Human1.15695117
99CIITA_25753668_ChIP-Seq_RAJI_Human1.15133632
100GATA1_22383799_ChIP-Seq_G1ME_Mouse1.15006574
101SA1_27219007_Chip-Seq_ERYTHROID_Human1.14775514
102CTCF_21964334_Chip-Seq_Bcells_Human1.14726200
103SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.13817048
104SPI1_23547873_ChIP-Seq_NB4_Human1.13123318
105SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.13022927
106TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.12293948
107CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.11798400
108CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.11575726
109P68_20966046_ChIP-Seq_HELA_Human1.11555257
110CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.07734080
111PHF8_20622854_ChIP-Seq_HELA_Human1.07696562
112PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.07485358
113SA1_27219007_Chip-Seq_Bcells_Human1.07469289
114FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.07380543
115CTCF_21964334_ChIP-Seq_BJAB-B_Human1.07246583
116CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.06931852
117NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.06046574
118EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.05917312
119STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.05377615
120RARB_27405468_Chip-Seq_BRAIN_Mouse1.04946466
121PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.04624194
122E2F1_20622854_ChIP-Seq_HELA_Human1.03834608
123TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.03781908
124ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.03766788
125YY1_22570637_ChIP-Seq_MALME-3M_Human1.03278064
126SMC4_20622854_ChIP-Seq_HELA_Human1.01542493
127SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.00262499
128P300_27058665_Chip-Seq_ZR-75-30cells_Human1.00240305
129CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.99771649
130FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.98007885
131VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.97084908
132GATA3_27048872_Chip-Seq_THYMUS_Human0.96778544

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004510_myositis4.30128864
2MP0003303_peritoneal_inflammation3.28380118
3MP0005451_abnormal_body_composition3.14604741
4MP0005058_abnormal_lysosome_morphology2.75370632
5MP0003436_decreased_susceptibility_to2.69630937
6MP0009840_abnormal_foam_cell2.62449147
7MP0001835_abnormal_antigen_presentation2.49462761
8MP0008260_abnormal_autophagy2.49232519
9MP0000465_gastrointestinal_hemorrhage2.41621896
10MP0004859_abnormal_synaptic_plasticity2.29153847
11MP0003763_abnormal_thymus_physiology2.28483939
12MP0003075_altered_response_to2.19234614
13MP0000685_abnormal_immune_system2.14552287
14MP0009785_altered_susceptibility_to2.14134717
15MP0003329_amyloid_beta_deposits2.11450894
16MP0000604_amyloidosis2.00897385
17MP0004858_abnormal_nervous_system2.00705424
18MP0002419_abnormal_innate_immunity1.95110654
19MP0005464_abnormal_platelet_physiology1.87988463
20MP0005000_abnormal_immune_tolerance1.87972515
21MP0002837_dystrophic_cardiac_calcinosis1.86959056
22MP0005025_abnormal_response_to1.86796581
23MP0003191_abnormal_cellular_cholesterol1.83612946
24MP0009278_abnormal_bone_marrow1.77384005
25MP0003172_abnormal_lysosome_physiology1.64108738
26MP0001800_abnormal_humoral_immune1.59605303
27MP0002452_abnormal_antigen_presenting1.59554880
28MP0005387_immune_system_phenotype1.56506697
29MP0001790_abnormal_immune_system1.56506697
30MP0002723_abnormal_immune_serum1.56237448
31MP0003300_gastrointestinal_ulcer1.55006107
32MP0005671_abnormal_response_to1.51877166
33MP0002148_abnormal_hypersensitivity_rea1.51102342
34MP0002166_altered_tumor_susceptibility1.51008321
35MP0003724_increased_susceptibility_to1.50457287
36MP0001533_abnormal_skeleton_physiology1.48233339
37MP0004947_skin_inflammation1.47589137
38MP0004130_abnormal_muscle_cell1.47490310
39MP0001819_abnormal_immune_cell1.46047871
40MP0002132_abnormal_respiratory_system1.45597951
41MP0002254_reproductive_system_inflammat1.44623939
42MP0002420_abnormal_adaptive_immunity1.44149802
43MP0008004_abnormal_stomach_pH1.42037970
44MP0005310_abnormal_salivary_gland1.41764491
45MP0005166_decreased_susceptibility_to1.39434632
46MP0003828_pulmonary_edema1.38987898
47MP0003656_abnormal_erythrocyte_physiolo1.38874217
48MP0005083_abnormal_biliary_tract1.36985655
49MP0005167_abnormal_blood-brain_barrier1.35617579
50MP0006082_CNS_inflammation1.33999594
51MP0000751_myopathy1.32247423
52MP0000703_abnormal_thymus_morphology1.30938825
53MP0000747_muscle_weakness1.30774871
54MP0000749_muscle_degeneration1.27600721
55MP0001545_abnormal_hematopoietic_system1.27498206
56MP0005397_hematopoietic_system_phenotyp1.27498206
57MP0001845_abnormal_inflammatory_respons1.27060939
58MP0003806_abnormal_nucleotide_metabolis1.26564475
59MP0001501_abnormal_sleep_pattern1.25752217
60MP0009764_decreased_sensitivity_to1.24591159
61MP0001873_stomach_inflammation1.24269883
62MP0000343_altered_response_to1.24023705
63MP0002909_abnormal_adrenal_gland1.22662215
64MP0001968_abnormal_touch/_nociception1.20118773
65MP0002736_abnormal_nociception_after1.17038105
66MP0003635_abnormal_synaptic_transmissio1.16296879
67MP0003279_aneurysm1.16061239
68MP0001853_heart_inflammation1.14415118
69MP0004270_analgesia1.12954107
70MP0000490_abnormal_crypts_of1.11189207
71MP0008469_abnormal_protein_level1.10470460
72MP0003866_abnormal_defecation1.09702092
73MP0002006_tumorigenesis1.09232474
74MP0000858_altered_metastatic_potential1.09063458
75MP0008874_decreased_physiological_sensi1.08587632
76MP0002396_abnormal_hematopoietic_system1.07431427
77MP0005535_abnormal_body_temperature1.06960156
78MP0008961_abnormal_basal_metabolism1.06310341
79MP0000716_abnormal_immune_system1.05236633
80MP0009333_abnormal_splenocyte_physiolog1.03333695
81MP0000015_abnormal_ear_pigmentation1.02459968
82MP0002405_respiratory_system_inflammati1.02350985
83MP0001348_abnormal_lacrimal_gland1.02089931
84MP0002733_abnormal_thermal_nociception0.98957195
85MP0002398_abnormal_bone_marrow0.98819124
86MP0005584_abnormal_enzyme/coenzyme_acti0.97656493
87MP0003705_abnormal_hypodermis_morpholog0.97219293
88MP0004381_abnormal_hair_follicle0.96662303
89MP0010155_abnormal_intestine_physiology0.96364796
90MP0002064_seizures0.95369109
91MP0003633_abnormal_nervous_system0.95257085
92MP0003453_abnormal_keratinocyte_physiol0.95152115
93MP0003566_abnormal_cell_adhesion0.93273604
94MP0001663_abnormal_digestive_system0.93039212
95MP0002735_abnormal_chemical_nociception0.92285776
96MP0005075_abnormal_melanosome_morpholog0.88586848
97MP0009763_increased_sensitivity_to0.86105877
98MP0003646_muscle_fatigue0.85951392
99MP0005330_cardiomyopathy0.85604165
100MP0003183_abnormal_peptide_metabolism0.85511329
101MP0002877_abnormal_melanocyte_morpholog0.85473310
102MP0000689_abnormal_spleen_morphology0.83632203
103MP0001970_abnormal_pain_threshold0.83051859
104MP0002998_abnormal_bone_remodeling0.81956954
105MP0002429_abnormal_blood_cell0.81601697
106MP0005501_abnormal_skin_physiology0.81287957
107MP0004036_abnormal_muscle_relaxation0.81191908
108MP0006036_abnormal_mitochondrial_physio0.80892276
109MP0003879_abnormal_hair_cell0.78709638
110MP0003448_altered_tumor_morphology0.77603403
111MP0004087_abnormal_muscle_fiber0.77241567
112MP0002722_abnormal_immune_system0.77129606
113MP0002063_abnormal_learning/memory/cond0.76716660
114MP0000920_abnormal_myelination0.76628300
115MP0004808_abnormal_hematopoietic_stem0.75834436
116MP0000249_abnormal_blood_vessel0.75753893
117MP0004185_abnormal_adipocyte_glucose0.73919359
118MP0003690_abnormal_glial_cell0.73287355
119MP0005390_skeleton_phenotype0.72907795
120MP0000750_abnormal_muscle_regeneration0.71827060
121MP0002106_abnormal_muscle_physiology0.71717744
122MP0002138_abnormal_hepatobiliary_system0.71715028
123MP0001851_eye_inflammation0.71652332
124MP0002796_impaired_skin_barrier0.71470462
125MP0005165_increased_susceptibility_to0.67703732
126MP0005666_abnormal_adipose_tissue0.67701250
127MP0005381_digestive/alimentary_phenotyp0.65084789
128MP0000678_abnormal_parathyroid_gland0.64565038
129MP0002019_abnormal_tumor_incidence0.63991106
130MP0001986_abnormal_taste_sensitivity0.63989019
131MP0003795_abnormal_bone_structure0.63141638
132MP0009765_abnormal_xenobiotic_induced0.62852260
133MP0009931_abnormal_skin_appearance0.61671980
134MP0002277_abnormal_respiratory_mucosa0.59506004
135MP0002933_joint_inflammation0.59331010

Predicted human phenotypes

RankGene SetZ-score
1Purpura (HP:0000979)4.35462273
2Recurrent abscess formation (HP:0002722)4.05131301
3Recurrent bacterial skin infections (HP:0005406)3.82052461
4Eczematoid dermatitis (HP:0000976)3.76280674
5Increased cerebral lipofuscin (HP:0011813)3.34487191
6Recurrent gram-negative bacterial infections (HP:0005420)3.12393210
7Supranuclear gaze palsy (HP:0000605)3.11037281
8Elevated erythrocyte sedimentation rate (HP:0003565)3.09423138
9Abnormal platelet volume (HP:0011876)3.03917383
10Abnormality of macrophages (HP:0004311)2.96039362
11Asymmetric septal hypertrophy (HP:0001670)2.95405182
12Increased neuronal autofluorescent lipopigment (HP:0002074)2.90662365
13Abnormality of the nasal mucosa (HP:0000433)2.89023548
14Hepatosplenomegaly (HP:0001433)2.86901479
15Dysostosis multiplex (HP:0000943)2.80087987
16Chronic otitis media (HP:0000389)2.78450953
17Nasal polyposis (HP:0100582)2.78269741
18Axonal loss (HP:0003447)2.75216736
19Myositis (HP:0100614)2.73661029
20Menorrhagia (HP:0000132)2.70829867
21Chest pain (HP:0100749)2.63419595
22Visual hallucinations (HP:0002367)2.60195091
23Encephalitis (HP:0002383)2.58500967
24Interstitial pulmonary disease (HP:0006530)2.56712587
25Hypertensive crisis (HP:0100735)2.56349304
26Increased IgM level (HP:0003496)2.56253228
27Cellulitis (HP:0100658)2.56064682
28Hypercortisolism (HP:0001578)2.55948425
29Panhypogammaglobulinemia (HP:0003139)2.55157211
30Increased mean platelet volume (HP:0011877)2.53622625
31Urinary glycosaminoglycan excretion (HP:0003541)2.48770791
32Mucopolysacchariduria (HP:0008155)2.48770791
33Cerebral inclusion bodies (HP:0100314)2.48323353
34Neurofibrillary tangles (HP:0002185)2.47265539
35Recurrent skin infections (HP:0001581)2.44518833
36Abnormality of the heme biosynthetic pathway (HP:0010472)2.44344271
37Recurrent cutaneous fungal infections (HP:0011370)2.41425969
38Chronic mucocutaneous candidiasis (HP:0002728)2.41425969
39Loss of speech (HP:0002371)2.40460393
40Achilles tendon contracture (HP:0001771)2.39788365
41Agammaglobulinemia (HP:0004432)2.38590903
42Myokymia (HP:0002411)2.36814400
43Ragged-red muscle fibers (HP:0003200)2.35448555
44Abnormality of the Achilles tendon (HP:0005109)2.30108253
45Retrobulbar optic neuritis (HP:0100654)2.29624011
46Optic neuritis (HP:0100653)2.29624011
47Mediastinal lymphadenopathy (HP:0100721)2.28234531
48Abnormality of iron homeostasis (HP:0011031)2.28095864
49Abnormality of polysaccharide metabolism (HP:0011012)2.27477505
50Abnormality of glycosaminoglycan metabolism (HP:0004371)2.27477505
51Abnormality of mucopolysaccharide metabolism (HP:0011020)2.27477505
52Vacuolated lymphocytes (HP:0001922)2.26607047
53Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.26203520
54Gastrointestinal stroma tumor (HP:0100723)2.24131849
55Urticaria (HP:0001025)2.23041502
56Gingivitis (HP:0000230)2.23004949
57Chronic obstructive pulmonary disease (HP:0006510)2.18551196
58Obstructive lung disease (HP:0006536)2.18551196
59Recurrent fungal infections (HP:0002841)2.18299206
60Peritonitis (HP:0002586)2.17098317
61Spontaneous hematomas (HP:0007420)2.16405433
62Hemorrhage of the eye (HP:0011885)2.14264189
63Orchitis (HP:0100796)2.13101677
64Abnormality of liposaccharide metabolism (HP:0010968)2.10416285
65Abnormality of glycosphingolipid metabolism (HP:0004343)2.10416285
66Abnormality of glycolipid metabolism (HP:0010969)2.10416285
67Amyloidosis (HP:0011034)2.07600150
68Bulbar palsy (HP:0001283)2.07225298
69Cerebral hemorrhage (HP:0001342)2.06731469
70Granulocytopenia (HP:0001913)2.06306745
71Tetraparesis (HP:0002273)2.05932601
72Distal lower limb muscle weakness (HP:0009053)2.05231068
73Petechiae (HP:0000967)2.05182224
74Gastrointestinal inflammation (HP:0004386)2.05153850
75Inflammation of the large intestine (HP:0002037)2.03284044
76Arterial thrombosis (HP:0004420)2.03047722
77Exercise-induced myalgia (HP:0003738)2.02710466
78Rapidly progressive (HP:0003678)2.02676976
79Centrally nucleated skeletal muscle fibers (HP:0003687)2.02417313
80Progressive neurologic deterioration (HP:0002344)2.02103151
81Polycythemia (HP:0001901)2.00857931
82Abnormal delayed hypersensitivity skin test (HP:0002963)1.99388690
83Abnormality of T cell physiology (HP:0011840)1.98066455
84Hypertriglyceridemia (HP:0002155)1.96243297
85Lymphopenia (HP:0001888)1.95928967
86Fatigue (HP:0012378)1.94605671
87Limb-girdle muscle atrophy (HP:0003797)1.94363807
88Episodic fever (HP:0001954)1.93857097
89Abnormality of T cells (HP:0002843)1.93726691
90Colitis (HP:0002583)1.93609287
91Systemic lupus erythematosus (HP:0002725)1.93579001
92Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.92291562
93Osteomyelitis (HP:0002754)1.92167773
94Gingival bleeding (HP:0000225)1.91480680
95Diminished motivation (HP:0000745)1.91462487
96Increased IgE level (HP:0003212)1.91138676
97Global brain atrophy (HP:0002283)1.90567392
98Frequent falls (HP:0002359)1.88610587
99Anorexia (HP:0002039)1.88482824
100Apathy (HP:0000741)1.86467721
101Cerebral aneurysm (HP:0004944)1.86033225
102Myoglobinuria (HP:0002913)1.85055277
103Thoracic kyphosis (HP:0002942)1.84826508
104Epistaxis (HP:0000421)1.84821955
105Hypochromic anemia (HP:0001931)1.84723860
106Sepsis (HP:0100806)1.84434020
107Bundle branch block (HP:0011710)1.82578971
108Cholecystitis (HP:0001082)1.81437774
109Abnormal gallbladder physiology (HP:0012438)1.81437774
110Mutism (HP:0002300)1.81265784
111Leukocytosis (HP:0001974)1.81025340
112Abnormality of cells of the lymphoid lineage (HP:0012140)1.80891029
113Vertebral compression fractures (HP:0002953)1.80113046
114Distal upper limb amyotrophy (HP:0007149)1.79122404
115Upper limb amyotrophy (HP:0009129)1.79122404
116Pulmonary embolism (HP:0002204)1.79015208
117Myopathic facies (HP:0002058)1.78870190
118Splenomegaly (HP:0001744)1.77459219
119Pulmonary infiltrates (HP:0002113)1.77106566
120Pustule (HP:0200039)1.76881869
121Gastrointestinal infarctions (HP:0005244)1.75018868
122Abnormal platelet function (HP:0011869)1.73437712
123Impaired platelet aggregation (HP:0003540)1.73437712
124Stomatitis (HP:0010280)1.73026557
125Dementia (HP:0000726)1.72718301
126Verrucae (HP:0200043)1.70998544
127Papilloma (HP:0012740)1.70998544
128Xanthomatosis (HP:0000991)1.70636619
129Increased serum ferritin (HP:0003281)1.70348379
130Exercise-induced muscle cramps (HP:0003710)1.69971939
131Meningitis (HP:0001287)1.69750486
132Vasculitis (HP:0002633)1.69351863
133Mitral stenosis (HP:0001718)1.68507549
134Hypergammaglobulinemia (HP:0010702)1.67894520
135Recurrent viral infections (HP:0004429)1.67704414
136Papilledema (HP:0001085)1.66021606
137Prolonged bleeding time (HP:0003010)1.66018564
138J-shaped sella turcica (HP:0002680)1.62407385
139Ankle clonus (HP:0011448)1.61126815
140Focal motor seizures (HP:0011153)1.60889033
141Neuronal loss in central nervous system (HP:0002529)1.60195203
142Hematochezia (HP:0002573)1.59671891

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB33.34774177
2RIPK43.26366148
3ERN13.10204175
4MAP3K92.89706353
5KSR22.72365041
6SMG12.60685191
7PKN22.48033439
8MAP4K12.44954968
9PRPF4B2.43079697
10ARAF2.15206730
11IRAK32.08914797
12CAMKK22.06406865
13MAP3K132.00067587
14IRAK41.97221347
15TBK11.93181550
16FES1.83527361
17EPHB11.79051946
18CAMKK11.75903148
19NME21.74913644
20TAOK21.69657507
21GRK61.57357561
22MAP3K31.55416210
23VRK21.54481420
24TAOK11.47059657
25MAP2K31.44766598
26RAF11.43765572
27NTRK11.42042550
28BLK1.39106548
29MAP3K11.37931102
30TYK21.37490032
31RIPK11.33885032
32SYK1.31888613
33MAP3K121.29188801
34TTN1.28780062
35PAK61.27715654
36MAP3K111.26694096
37SIK11.19592773
38PDK11.18074757
39JAK31.17737288
40PDPK11.17687370
41LRRK21.16649396
42KDR1.12478087
43CDK191.12236362
44BTK1.11924178
45GRK51.10791587
46FGR1.10164539
47ZAP701.08431642
48KIT1.06238803
49SIK31.06019790
50EEF2K1.03886934
51TNK21.03214075
52HCK1.02451183
53JAK21.00717353
54MUSK0.97925153
55MST1R0.96410336
56LYN0.94501506
57IRAK20.93197317
58JAK10.91550558
59CSK0.91503274
60PIM20.90251517
61PRKD20.89320542
62ICK0.88826214
63MATK0.88609785
64RPS6KA20.87628505
65RET0.86631534
66SIK20.85267834
67TESK20.83168454
68MAP2K40.83117940
69DYRK1B0.81192091
70MAP3K70.79804128
71BMX0.78521954
72MAPK110.77381969
73FGFR40.77140464
74MAP3K100.75885930
75SCYL20.75861284
76MAP3K50.72683153
77LCK0.72552160
78MINK10.72284220
79MOS0.71989375
80MAP3K60.71773925
81CSF1R0.71070192
82KSR10.70970117
83TGFBR20.70806645
84MARK20.70630370
85TXK0.70590896
86IKBKB0.70307424
87ABL20.69678652
88ALK0.69631710
89LMTK20.68638947
90PTK2B0.68592632
91MAP3K40.68078655
92PTK60.66148400
93STK110.65903459
94TAOK30.64674346
95PRKG20.64186541
96FLT30.63657076
97MAPK120.62959735
98DAPK30.62286415
99CAMK1D0.61767815
100MAP3K20.61751128
101IKBKE0.60971256
102MARK30.60717436
103MAP2K10.60513905
104RPS6KC10.59213932
105RPS6KL10.59213932
106PHKG20.58972113
107PHKG10.58972113
108NTRK30.57896171
109DAPK20.57796945
110MAPK40.57483033
111MAP4K20.56432585
112ITK0.56183514
113MAP2K20.55685122
114HIPK20.55585484
115PIM10.52321832
116RPS6KA40.50910856
117PTK20.50514162
118PRKCH0.49262154
119PAK40.49216979
120STK100.48577006
121CAMK1G0.48129942
122BCKDK0.47561821
123CAMK10.47193844
124MAP3K140.45464004
125MAPKAPK30.45359629
126DAPK10.44931469
127TEC0.44885458
128DMPK0.44603798
129TESK10.42928050
130RPS6KA60.42631842
131DYRK30.42465855
132CDK40.42385321
133EPHA40.42061861
134ILK0.41997621
135PRKD30.40627153
136PRKD10.40290997
137IRAK10.39734951
138CDC42BPA0.37449265
139MAPKAPK20.36606301
140FYN0.35512476

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053402.38193451
2Leishmaniasis_Homo sapiens_hsa051402.20949310
3Nitrogen metabolism_Homo sapiens_hsa009102.19198504
4Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006042.14448377
5Allograft rejection_Homo sapiens_hsa053302.12527412
6Sulfur relay system_Homo sapiens_hsa041222.11611274
7Graft-versus-host disease_Homo sapiens_hsa053322.01565221
8Autoimmune thyroid disease_Homo sapiens_hsa053201.95174748
9Osteoclast differentiation_Homo sapiens_hsa043801.87206591
10Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.84776778
11Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.84574418
12Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.74692422
13Staphylococcus aureus infection_Homo sapiens_hsa051501.74516118
14Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.72068600
15B cell receptor signaling pathway_Homo sapiens_hsa046621.69829715
16Other glycan degradation_Homo sapiens_hsa005111.67000117
17Hematopoietic cell lineage_Homo sapiens_hsa046401.61446892
18Lysosome_Homo sapiens_hsa041421.51025974
19Synaptic vesicle cycle_Homo sapiens_hsa047211.48991720
20Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.46658262
21Pentose phosphate pathway_Homo sapiens_hsa000301.43540414
22Herpes simplex infection_Homo sapiens_hsa051681.43066804
23Pertussis_Homo sapiens_hsa051331.41225896
24Tuberculosis_Homo sapiens_hsa051521.40022951
25Intestinal immune network for IgA production_Homo sapiens_hsa046721.39784092
26Shigellosis_Homo sapiens_hsa051311.28851697
27Salmonella infection_Homo sapiens_hsa051321.27357928
28VEGF signaling pathway_Homo sapiens_hsa043701.26592215
29Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.25350976
30Glycosaminoglycan degradation_Homo sapiens_hsa005311.25255262
31Asthma_Homo sapiens_hsa053101.23734440
32Adipocytokine signaling pathway_Homo sapiens_hsa049201.22847777
33Influenza A_Homo sapiens_hsa051641.22819841
34Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.22009071
35Neurotrophin signaling pathway_Homo sapiens_hsa047221.21035932
36Fructose and mannose metabolism_Homo sapiens_hsa000511.17267985
37Toll-like receptor signaling pathway_Homo sapiens_hsa046201.14294057
38Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.13837114
39Pancreatic cancer_Homo sapiens_hsa052121.11773005
40Galactose metabolism_Homo sapiens_hsa000521.11403114
41Long-term potentiation_Homo sapiens_hsa047201.10615061
42Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.07429016
43Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.05552444
44Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.03713419
45Platelet activation_Homo sapiens_hsa046111.03267878
46SNARE interactions in vesicular transport_Homo sapiens_hsa041301.02137377
47Salivary secretion_Homo sapiens_hsa049701.01203885
48Chemokine signaling pathway_Homo sapiens_hsa040621.01109295
49Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.99972111
50Acute myeloid leukemia_Homo sapiens_hsa052210.98402857
51Insulin resistance_Homo sapiens_hsa049310.97001031
52Bladder cancer_Homo sapiens_hsa052190.95016659
53Hepatitis C_Homo sapiens_hsa051600.93470919
54Notch signaling pathway_Homo sapiens_hsa043300.92274647
55Carbohydrate digestion and absorption_Homo sapiens_hsa049730.91579375
56Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.91504096
57Toxoplasmosis_Homo sapiens_hsa051450.89979680
58TNF signaling pathway_Homo sapiens_hsa046680.87614270
59Gastric acid secretion_Homo sapiens_hsa049710.87558571
60Phagosome_Homo sapiens_hsa041450.86753091
61Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.86393725
62African trypanosomiasis_Homo sapiens_hsa051430.86357935
63Endocytosis_Homo sapiens_hsa041440.85501951
64Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.83737217
65GnRH signaling pathway_Homo sapiens_hsa049120.83657618
66Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.82787140
67Viral carcinogenesis_Homo sapiens_hsa052030.82653912
68Amoebiasis_Homo sapiens_hsa051460.81630249
69Prion diseases_Homo sapiens_hsa050200.80499409
70Epstein-Barr virus infection_Homo sapiens_hsa051690.80199243
71Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.79899428
72Chronic myeloid leukemia_Homo sapiens_hsa052200.78271362
73Cholinergic synapse_Homo sapiens_hsa047250.78164379
74Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.78146752
75AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.78098180
76Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.77230421
77Aldosterone synthesis and secretion_Homo sapiens_hsa049250.76861246
78Sulfur metabolism_Homo sapiens_hsa009200.76418411
79Renin secretion_Homo sapiens_hsa049240.76211220
80Non-small cell lung cancer_Homo sapiens_hsa052230.75634841
81Legionellosis_Homo sapiens_hsa051340.75512295
82Oxytocin signaling pathway_Homo sapiens_hsa049210.75229729
83Malaria_Homo sapiens_hsa051440.75098639
84Cyanoamino acid metabolism_Homo sapiens_hsa004600.74896115
85Dopaminergic synapse_Homo sapiens_hsa047280.73988067
86Dorso-ventral axis formation_Homo sapiens_hsa043200.73465381
87Rheumatoid arthritis_Homo sapiens_hsa053230.73113009
88Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.72939665
89Apoptosis_Homo sapiens_hsa042100.72657197
90Collecting duct acid secretion_Homo sapiens_hsa049660.71886731
91Leukocyte transendothelial migration_Homo sapiens_hsa046700.71881029
92Estrogen signaling pathway_Homo sapiens_hsa049150.71303826
93Circadian entrainment_Homo sapiens_hsa047130.70167182
94Prolactin signaling pathway_Homo sapiens_hsa049170.67973016
95Insulin secretion_Homo sapiens_hsa049110.67533145
96mTOR signaling pathway_Homo sapiens_hsa041500.66913223
97NOD-like receptor signaling pathway_Homo sapiens_hsa046210.66671149
98Arginine biosynthesis_Homo sapiens_hsa002200.66382319
99Glioma_Homo sapiens_hsa052140.66300158
100GABAergic synapse_Homo sapiens_hsa047270.65830747
101Systemic lupus erythematosus_Homo sapiens_hsa053220.64881908
102Amphetamine addiction_Homo sapiens_hsa050310.64582118
103Jak-STAT signaling pathway_Homo sapiens_hsa046300.64406437
104Type II diabetes mellitus_Homo sapiens_hsa049300.64032803
105Cocaine addiction_Homo sapiens_hsa050300.62605242
106Olfactory transduction_Homo sapiens_hsa047400.62151104
107Sphingolipid signaling pathway_Homo sapiens_hsa040710.61951561
108T cell receptor signaling pathway_Homo sapiens_hsa046600.61546225
109Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.61448858
110Insulin signaling pathway_Homo sapiens_hsa049100.60874759
111Vibrio cholerae infection_Homo sapiens_hsa051100.60567256
112MAPK signaling pathway_Homo sapiens_hsa040100.60515232
113Bile secretion_Homo sapiens_hsa049760.58804853
114Endometrial cancer_Homo sapiens_hsa052130.58803527
115Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.58784153
116Central carbon metabolism in cancer_Homo sapiens_hsa052300.58341637
117Viral myocarditis_Homo sapiens_hsa054160.58202067
118Morphine addiction_Homo sapiens_hsa050320.57974522
119Phospholipase D signaling pathway_Homo sapiens_hsa040720.57669141
120HTLV-I infection_Homo sapiens_hsa051660.57555514
121Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.57536074
122Hepatitis B_Homo sapiens_hsa051610.55609250
123Glycerophospholipid metabolism_Homo sapiens_hsa005640.55572160
124Type I diabetes mellitus_Homo sapiens_hsa049400.54242295
125Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.52413229
126Pancreatic secretion_Homo sapiens_hsa049720.51381092
127Renal cell carcinoma_Homo sapiens_hsa052110.51215341
128Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.51160698
129Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.51001942
130Regulation of autophagy_Homo sapiens_hsa041400.49578994
131Phosphatidylinositol signaling system_Homo sapiens_hsa040700.48457449
132RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.48365094
133Antigen processing and presentation_Homo sapiens_hsa046120.47715640
134NF-kappa B signaling pathway_Homo sapiens_hsa040640.47514321
135Glutamatergic synapse_Homo sapiens_hsa047240.46447608
136Measles_Homo sapiens_hsa051620.45864566
137HIF-1 signaling pathway_Homo sapiens_hsa040660.45609142
138Transcriptional misregulation in cancer_Homo sapiens_hsa052020.42822541
139Colorectal cancer_Homo sapiens_hsa052100.42734169
140Inositol phosphate metabolism_Homo sapiens_hsa005620.40060281
141Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.39450217

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