BORCS7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial electron transport, NADH to ubiquinone (GO:0006120)5.30737324
2ATP synthesis coupled proton transport (GO:0015986)4.88814584
3energy coupled proton transport, down electrochemical gradient (GO:0015985)4.88814584
4presynaptic membrane assembly (GO:0097105)4.88296047
5mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.82839778
6central nervous system myelination (GO:0022010)4.74638828
7axon ensheathment in central nervous system (GO:0032291)4.74638828
8presynaptic membrane organization (GO:0097090)4.47330397
9respiratory electron transport chain (GO:0022904)4.17934061
10neuron cell-cell adhesion (GO:0007158)4.13220361
11electron transport chain (GO:0022900)4.08847339
12platelet dense granule organization (GO:0060155)4.06482301
13postsynaptic membrane organization (GO:0001941)4.03814480
14long-chain fatty acid biosynthetic process (GO:0042759)3.86830728
15chaperone-mediated protein transport (GO:0072321)3.83777995
16protein complex biogenesis (GO:0070271)3.75638258
17epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.70714164
18water-soluble vitamin biosynthetic process (GO:0042364)3.69030696
19respiratory chain complex IV assembly (GO:0008535)3.65729992
20mannosylation (GO:0097502)3.64383891
21neuronal action potential propagation (GO:0019227)3.59787022
22protein neddylation (GO:0045116)3.59581038
23sequestering of actin monomers (GO:0042989)3.54832860
24behavioral response to nicotine (GO:0035095)3.49842694
25mitochondrial respiratory chain complex I assembly (GO:0032981)3.49160857
26NADH dehydrogenase complex assembly (GO:0010257)3.49160857
27mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.49160857
28epithelial cilium movement (GO:0003351)3.46732542
29protein localization to cilium (GO:0061512)3.42915353
30GPI anchor biosynthetic process (GO:0006506)3.41718606
31positive regulation of inositol phosphate biosynthetic process (GO:0060732)3.41364488
32negative regulation of synaptic transmission, GABAergic (GO:0032229)3.33117709
33cytochrome complex assembly (GO:0017004)3.32484600
34GTP biosynthetic process (GO:0006183)3.31248349
35response to pheromone (GO:0019236)3.26298320
36regulation of cilium movement (GO:0003352)3.25847680
37axoneme assembly (GO:0035082)3.21202397
38mitochondrial respiratory chain complex assembly (GO:0033108)3.15378221
39negative regulation of neurotransmitter transport (GO:0051589)3.15281696
40intraciliary transport (GO:0042073)3.14542175
41pyrimidine nucleobase catabolic process (GO:0006208)3.12811679
42protein-cofactor linkage (GO:0018065)3.12111587
43positive regulation of synapse assembly (GO:0051965)3.09524703
44cilium movement (GO:0003341)3.07935757
45detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.07753452
46GPI anchor metabolic process (GO:0006505)3.07647828
47cranial nerve morphogenesis (GO:0021602)3.07058450
48proteasome assembly (GO:0043248)3.06887576
49L-fucose metabolic process (GO:0042354)3.06026870
50L-fucose catabolic process (GO:0042355)3.06026870
51fucose catabolic process (GO:0019317)3.06026870
52regulation of hexokinase activity (GO:1903299)3.03935578
53regulation of glucokinase activity (GO:0033131)3.03935578
54regulation of catecholamine metabolic process (GO:0042069)3.03870511
55regulation of dopamine metabolic process (GO:0042053)3.03870511
56preassembly of GPI anchor in ER membrane (GO:0016254)3.03041287
57tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.02075638
58RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.02075638
59protein localization to synapse (GO:0035418)3.01874870
60positive regulation of protein homodimerization activity (GO:0090073)2.95594410
61cellular ketone body metabolic process (GO:0046950)2.94824721
62gamma-aminobutyric acid signaling pathway (GO:0007214)2.94514469
63dopamine transport (GO:0015872)2.92639548
64short-term memory (GO:0007614)2.89378817
65indolalkylamine metabolic process (GO:0006586)2.87096373
66protein polyglutamylation (GO:0018095)2.86172975
67ubiquinone biosynthetic process (GO:0006744)2.85031601
68dopamine biosynthetic process (GO:0042416)2.83246467
69righting reflex (GO:0060013)2.83114096
70hydrogen ion transmembrane transport (GO:1902600)2.82534903
71ATP biosynthetic process (GO:0006754)2.81148690
72tryptophan catabolic process (GO:0006569)2.80045657
73indole-containing compound catabolic process (GO:0042436)2.80045657
74indolalkylamine catabolic process (GO:0046218)2.80045657
75vocalization behavior (GO:0071625)2.77965663
76ketone body metabolic process (GO:1902224)2.76741701
77regulation of pigment cell differentiation (GO:0050932)2.75239018
78anterograde synaptic vesicle transport (GO:0048490)2.72703564
79regulation of inositol phosphate biosynthetic process (GO:0010919)2.72274039
80inner ear receptor stereocilium organization (GO:0060122)2.72181319
81negative regulation of telomere maintenance (GO:0032205)2.70977584
82C-terminal protein lipidation (GO:0006501)2.70095719
83glutamate receptor signaling pathway (GO:0007215)2.65587287
84ubiquinone metabolic process (GO:0006743)2.64864997
85G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.64579946
86fatty acid elongation (GO:0030497)2.64281305
87proton transport (GO:0015992)2.64206464
88C-terminal protein amino acid modification (GO:0018410)2.61896431
89nucleobase catabolic process (GO:0046113)2.61322689
90neurotransmitter uptake (GO:0001504)2.61018141
91serotonin receptor signaling pathway (GO:0007210)2.59937955
92intracellular protein transmembrane import (GO:0044743)2.59723278
93sympathetic nervous system development (GO:0048485)2.59268193
94startle response (GO:0001964)2.58425743
95DNA deamination (GO:0045006)2.58203181
96regulation of microtubule-based movement (GO:0060632)2.56297326
97hydrogen transport (GO:0006818)2.56100956
98organelle disassembly (GO:1903008)2.55871771
99regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.55779990
100inositol phosphate catabolic process (GO:0071545)2.55546394
101cilium morphogenesis (GO:0060271)2.55427030
102cilium organization (GO:0044782)2.55107111
103limb bud formation (GO:0060174)2.54087139
104transmission of nerve impulse (GO:0019226)2.53686304
105ionotropic glutamate receptor signaling pathway (GO:0035235)2.53233474
106cerebral cortex radially oriented cell migration (GO:0021799)2.52730927
107piRNA metabolic process (GO:0034587)2.52515255
108positive regulation of action potential (GO:0045760)2.51812769
109negative regulation of execution phase of apoptosis (GO:1900118)2.51482712
110neuron fate determination (GO:0048664)2.50929280
111gamma-aminobutyric acid transport (GO:0015812)2.50560857
112auditory receptor cell stereocilium organization (GO:0060088)2.49790219
113ribosomal small subunit biogenesis (GO:0042274)2.49386075
114developmental pigmentation (GO:0048066)2.49198264
115regulation of protein kinase A signaling (GO:0010738)2.48885233
116aromatic amino acid family catabolic process (GO:0009074)2.48539258
117cilium assembly (GO:0042384)2.47908102
118keratinocyte development (GO:0003334)2.46954882
119benzene-containing compound metabolic process (GO:0042537)2.46750340
120regulation of glutamate secretion (GO:0014048)2.46008308
121lymphoid progenitor cell differentiation (GO:0002320)2.45666736
122neurotransmitter catabolic process (GO:0042135)2.45190700
123UTP biosynthetic process (GO:0006228)2.45190242
124glycolipid biosynthetic process (GO:0009247)2.44832026
125parturition (GO:0007567)2.44262833
126purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.43567680
127regulation of feeding behavior (GO:0060259)2.43056659
128tryptophan metabolic process (GO:0006568)2.41580848
129neuron recognition (GO:0008038)2.41388865
130anterograde axon cargo transport (GO:0008089)2.40933363
131regulation of timing of cell differentiation (GO:0048505)2.40699265
132nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.39823948
133synaptic transmission, cholinergic (GO:0007271)2.38935862
134nonmotile primary cilium assembly (GO:0035058)2.38604234
135regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.38367482
136regulation of synapse assembly (GO:0051963)2.38183816
137termination of RNA polymerase III transcription (GO:0006386)2.38105644
138transcription elongation from RNA polymerase III promoter (GO:0006385)2.38105644
139neuron-neuron synaptic transmission (GO:0007270)2.36399646
140quinone biosynthetic process (GO:1901663)2.36038222
141regulation of respiratory system process (GO:0044065)2.35647397
142aldehyde catabolic process (GO:0046185)2.35528728
143kynurenine metabolic process (GO:0070189)2.35409473
144indole-containing compound metabolic process (GO:0042430)2.34669352
145L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.34541037
146positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.33638099
147purine nucleoside triphosphate biosynthetic process (GO:0009145)2.33151864
148cellular biogenic amine catabolic process (GO:0042402)2.32902253
149amine catabolic process (GO:0009310)2.32902253
150positive regulation of cellular amine metabolic process (GO:0033240)2.32602141
151neuronal action potential (GO:0019228)2.32596836
152protein heterotetramerization (GO:0051290)2.32584779
153CTP metabolic process (GO:0046036)2.32316198
154CTP biosynthetic process (GO:0006241)2.32316198
155inner mitochondrial membrane organization (GO:0007007)2.30620768
156establishment of protein localization to mitochondrial membrane (GO:0090151)2.30477673
157phosphorylated carbohydrate dephosphorylation (GO:0046838)2.29812712
158inositol phosphate dephosphorylation (GO:0046855)2.29812712
159amino acid salvage (GO:0043102)2.29221095
160L-methionine salvage (GO:0071267)2.29221095
161L-methionine biosynthetic process (GO:0071265)2.29221095
162axonemal dynein complex assembly (GO:0070286)2.28185749
163regulation of respiratory gaseous exchange (GO:0043576)2.27687862
164detection of calcium ion (GO:0005513)2.26529122
165guanosine-containing compound biosynthetic process (GO:1901070)2.25580708
166neuron remodeling (GO:0016322)2.24854271
167cranial nerve development (GO:0021545)2.24123414
168calcium-mediated signaling using intracellular calcium source (GO:0035584)2.23330835

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.53962509
2GBX2_23144817_ChIP-Seq_PC3_Human3.81953336
3ZNF274_21170338_ChIP-Seq_K562_Hela2.97821172
4TAF15_26573619_Chip-Seq_HEK293_Human2.92271305
5SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.69915713
6ZFP57_27257070_Chip-Seq_ESCs_Mouse2.67735820
7JARID2_20064375_ChIP-Seq_MESCs_Mouse2.67163175
8CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.61984356
9TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.56286890
10BMI1_23680149_ChIP-Seq_NPCS_Mouse2.51562581
11EZH2_27304074_Chip-Seq_ESCs_Mouse2.48360381
12SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.44490925
13GABP_17652178_ChIP-ChIP_JURKAT_Human2.36832744
14GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.32769234
15EED_16625203_ChIP-ChIP_MESCs_Mouse2.26403180
16CBX2_27304074_Chip-Seq_ESCs_Mouse2.22179327
17SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.17867426
18VDR_22108803_ChIP-Seq_LS180_Human2.17703477
19SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.15188621
20GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.14966389
21JARID2_20075857_ChIP-Seq_MESCs_Mouse2.13320078
22SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.09880834
23SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.04893088
24POU3F2_20337985_ChIP-ChIP_501MEL_Human2.04584832
25IGF1R_20145208_ChIP-Seq_DFB_Human1.96370988
26EZH2_18974828_ChIP-Seq_MESCs_Mouse1.94215840
27RNF2_18974828_ChIP-Seq_MESCs_Mouse1.94215840
28CTBP1_25329375_ChIP-Seq_LNCAP_Human1.91175349
29EST1_17652178_ChIP-ChIP_JURKAT_Human1.89908376
30PCGF2_27294783_Chip-Seq_ESCs_Mouse1.88109034
31PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.83539309
32FUS_26573619_Chip-Seq_HEK293_Human1.82235267
33P300_19829295_ChIP-Seq_ESCs_Human1.80197799
34CTBP2_25329375_ChIP-Seq_LNCAP_Human1.79118756
35FLI1_27457419_Chip-Seq_LIVER_Mouse1.76532525
36FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.75893315
37EZH2_27294783_Chip-Seq_ESCs_Mouse1.73688633
38SUZ12_27294783_Chip-Seq_ESCs_Mouse1.71591936
39HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.68337626
40RNF2_27304074_Chip-Seq_NSC_Mouse1.66910954
41SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.63338077
42MTF2_20144788_ChIP-Seq_MESCs_Mouse1.61447446
43BCAT_22108803_ChIP-Seq_LS180_Human1.56639632
44ER_23166858_ChIP-Seq_MCF-7_Human1.55539803
45PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.54256415
46RNF2_27304074_Chip-Seq_ESCs_Mouse1.53891349
47RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.51762243
48EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.47156556
49REST_21632747_ChIP-Seq_MESCs_Mouse1.46712337
50E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.46451350
51NANOG_18555785_Chip-Seq_ESCs_Mouse1.45818884
52IKZF1_21737484_ChIP-ChIP_HCT116_Human1.45145692
53MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.44704471
54CBP_20019798_ChIP-Seq_JUKART_Human1.44095178
55IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.44095178
56AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.43689130
57SUZ12_27294783_Chip-Seq_NPCs_Mouse1.43278371
58EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.43117734
59IRF1_19129219_ChIP-ChIP_H3396_Human1.42916187
60MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.42515276
61AR_25329375_ChIP-Seq_VCAP_Human1.41417524
62NANOG_19829295_ChIP-Seq_ESCs_Human1.40888144
63SOX2_19829295_ChIP-Seq_ESCs_Human1.40888144
64TP53_22573176_ChIP-Seq_HFKS_Human1.40032305
65SMAD3_21741376_ChIP-Seq_EPCs_Human1.37418952
66ELK1_19687146_ChIP-ChIP_HELA_Human1.35516871
67P53_22387025_ChIP-Seq_ESCs_Mouse1.35286307
68SUZ12_18555785_Chip-Seq_ESCs_Mouse1.34293535
69TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.33952042
70SMAD4_21799915_ChIP-Seq_A2780_Human1.33425750
71NFE2_27457419_Chip-Seq_LIVER_Mouse1.32424453
72FOXA1_25329375_ChIP-Seq_VCAP_Human1.31262410
73FOXA1_27270436_Chip-Seq_PROSTATE_Human1.31262410
74SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.30740561
75EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.30709507
76OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.29635959
77HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.29099286
78GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.28097681
79STAT3_18555785_Chip-Seq_ESCs_Mouse1.28082036
80CDX2_19796622_ChIP-Seq_MESCs_Mouse1.27945939
81E2F1_18555785_Chip-Seq_ESCs_Mouse1.27542525
82NR3C1_21868756_ChIP-Seq_MCF10A_Human1.26671706
83TOP2B_26459242_ChIP-Seq_MCF-7_Human1.26519006
84KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.26456490
85CMYC_18555785_Chip-Seq_ESCs_Mouse1.26387289
86EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.26127234
87ELF1_17652178_ChIP-ChIP_JURKAT_Human1.25378352
88UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.24959673
89P300_18555785_Chip-Seq_ESCs_Mouse1.24889621
90TCF4_22108803_ChIP-Seq_LS180_Human1.24623397
91PCGF2_27294783_Chip-Seq_NPCs_Mouse1.24318284
92TAL1_26923725_Chip-Seq_HPCs_Mouse1.24173707
93PIAS1_25552417_ChIP-Seq_VCAP_Human1.22367964
94RUNX1_27457419_Chip-Seq_LIVER_Mouse1.21893397
95EZH2_27294783_Chip-Seq_NPCs_Mouse1.21326572
96POU5F1_16153702_ChIP-ChIP_HESCs_Human1.21294075
97CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.20211323
98FOXA1_21572438_ChIP-Seq_LNCaP_Human1.19802683
99NMYC_18555785_Chip-Seq_ESCs_Mouse1.19685993
100MYC_18940864_ChIP-ChIP_HL60_Human1.18042646
101AR_21572438_ChIP-Seq_LNCaP_Human1.17953150
102SOX2_18555785_Chip-Seq_ESCs_Mouse1.17888967
103AR_20517297_ChIP-Seq_VCAP_Human1.16383927
104VDR_23849224_ChIP-Seq_CD4+_Human1.15945186
105EWS_26573619_Chip-Seq_HEK293_Human1.15124137
106HTT_18923047_ChIP-ChIP_STHdh_Human1.14621505
107FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.12965185
108SRF_21415370_ChIP-Seq_HL-1_Mouse1.12654356
109KLF5_20875108_ChIP-Seq_MESCs_Mouse1.11070261
110CRX_20693478_ChIP-Seq_RETINA_Mouse1.11017304
111CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.11001931
112FLI1_21867929_ChIP-Seq_TH2_Mouse1.09634160
113ETV2_25802403_ChIP-Seq_MESCs_Mouse1.08874274
114NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.08749386
115BP1_19119308_ChIP-ChIP_Hs578T_Human1.07775733
116MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.07644796
117NCOR_22424771_ChIP-Seq_293T_Human1.07168825
118STAT3_23295773_ChIP-Seq_U87_Human1.06734401
119TCF4_23295773_ChIP-Seq_U87_Human1.06492298
120KLF4_18555785_Chip-Seq_ESCs_Mouse1.05421736
121SMAD1_18555785_Chip-Seq_ESCs_Mouse1.04094259
122REST_18959480_ChIP-ChIP_MESCs_Mouse1.04045987
123CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.03606797
124RUNX2_22187159_ChIP-Seq_PCA_Human1.03561279
125TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03542691
126POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.03542691
127TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.03381001
128CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.03157284
129RBPJ_22232070_ChIP-Seq_NCS_Mouse1.02860336
130ZFX_18555785_Chip-Seq_ESCs_Mouse1.02486005
131KDM2B_26808549_Chip-Seq_REH_Human1.02458006
132OCT4_18555785_Chip-Seq_ESCs_Mouse1.02234705
133EGR1_23403033_ChIP-Seq_LIVER_Mouse1.00657794
134PRDM14_20953172_ChIP-Seq_ESCs_Human1.00027745
135PU1_27457419_Chip-Seq_LIVER_Mouse0.99979352
136SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.99435343
137CTCF_18555785_Chip-Seq_ESCs_Mouse0.99287034
138JUN_21703547_ChIP-Seq_K562_Human0.98601796
139RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.98267428
140SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.98072814
141NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.97653769
142TP53_18474530_ChIP-ChIP_U2OS_Human0.96437314
143GATA3_21878914_ChIP-Seq_MCF-7_Human0.96268487
144SMAD_19615063_ChIP-ChIP_OVARY_Human0.95370545

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.62947323
2MP0001188_hyperpigmentation3.28566629
3MP0005409_darkened_coat_color3.04959091
4MP0009379_abnormal_foot_pigmentation2.91090322
5MP0003136_yellow_coat_color2.81396362
6MP0006292_abnormal_olfactory_placode2.72912462
7MP0008875_abnormal_xenobiotic_pharmacok2.59733464
8MP0006276_abnormal_autonomic_nervous2.59294125
9MP0000569_abnormal_digit_pigmentation2.57196721
10MP0001905_abnormal_dopamine_level2.52078236
11MP0001968_abnormal_touch/_nociception2.50174801
12MP0001529_abnormal_vocalization2.46404459
13MP0009745_abnormal_behavioral_response2.33809352
14MP0003195_calcinosis2.23143514
15MP0002272_abnormal_nervous_system2.22181682
16MP0009046_muscle_twitch2.21210242
17MP0003635_abnormal_synaptic_transmissio2.17109420
18MP0001986_abnormal_taste_sensitivity2.12763157
19MP0005423_abnormal_somatic_nervous2.12612955
20MP0002736_abnormal_nociception_after2.11007365
21MP0002064_seizures2.09451349
22MP0001486_abnormal_startle_reflex2.08169800
23MP0002638_abnormal_pupillary_reflex2.05775998
24MP0002735_abnormal_chemical_nociception2.02192581
25MP0008877_abnormal_DNA_methylation1.98835694
26MP0002102_abnormal_ear_morphology1.95122442
27MP0004142_abnormal_muscle_tone1.95109504
28MP0004270_analgesia1.93856212
29MP0002572_abnormal_emotion/affect_behav1.91742487
30MP0005084_abnormal_gallbladder_morpholo1.87436586
31MP0004859_abnormal_synaptic_plasticity1.83996193
32MP0002734_abnormal_mechanical_nocicepti1.82722964
33MP0003011_delayed_dark_adaptation1.82581114
34MP0004742_abnormal_vestibular_system1.79955955
35MP0002067_abnormal_sensory_capabilities1.77032557
36MP0004885_abnormal_endolymph1.76543390
37MP0001440_abnormal_grooming_behavior1.75263138
38MP0002876_abnormal_thyroid_physiology1.74412012
39MP0010386_abnormal_urinary_bladder1.73353011
40MP0001984_abnormal_olfaction1.71534651
41MP0004381_abnormal_hair_follicle1.67430775
42MP0001970_abnormal_pain_threshold1.65871860
43MP0000015_abnormal_ear_pigmentation1.62448672
44MP0002063_abnormal_learning/memory/cond1.61800447
45MP0001501_abnormal_sleep_pattern1.60396092
46MP0005646_abnormal_pituitary_gland1.54861866
47MP0005171_absent_coat_pigmentation1.54372234
48MP0002928_abnormal_bile_duct1.53723670
49MP0005645_abnormal_hypothalamus_physiol1.52313392
50MP0008872_abnormal_physiological_respon1.49355127
51MP0002184_abnormal_innervation1.48724050
52MP0000778_abnormal_nervous_system1.47731281
53MP0002733_abnormal_thermal_nociception1.47471656
54MP0000920_abnormal_myelination1.46985208
55MP0002557_abnormal_social/conspecific_i1.45289322
56MP0003283_abnormal_digestive_organ1.42586923
57MP0003252_abnormal_bile_duct1.40909362
58MP0003186_abnormal_redox_activity1.40746270
59MP0005379_endocrine/exocrine_gland_phen1.39952651
60MP0005551_abnormal_eye_electrophysiolog1.38229899
61MP0005085_abnormal_gallbladder_physiolo1.37478649
62MP0001963_abnormal_hearing_physiology1.29791031
63MP0002139_abnormal_hepatobiliary_system1.28919373
64MP0000026_abnormal_inner_ear1.28642008
65MP0000631_abnormal_neuroendocrine_gland1.28500907
66MP0004133_heterotaxia1.27959152
67MP0001502_abnormal_circadian_rhythm1.27254658
68MP0000372_irregular_coat_pigmentation1.25848869
69MP0006072_abnormal_retinal_apoptosis1.24869071
70MP0000566_synostosis1.23788347
71MP0005174_abnormal_tail_pigmentation1.23733533
72MP0003938_abnormal_ear_development1.16560579
73MP0002163_abnormal_gland_morphology1.16098739
74MP0003806_abnormal_nucleotide_metabolis1.15913138
75MP0003724_increased_susceptibility_to1.13778565
76MP0005365_abnormal_bile_salt1.13690021
77MP0001485_abnormal_pinna_reflex1.13073872
78MP0004145_abnormal_muscle_electrophysio1.12592155
79MP0006036_abnormal_mitochondrial_physio1.11974670
80MP0002752_abnormal_somatic_nervous1.10060053
81MP0004043_abnormal_pH_regulation1.08691834
82MP0005332_abnormal_amino_acid1.08181607
83MP0002909_abnormal_adrenal_gland1.06196075
84MP0009697_abnormal_copulation1.04109267
85MP0005386_behavior/neurological_phenoty1.03939607
86MP0004924_abnormal_behavior1.03939607
87MP0003122_maternal_imprinting1.03718320
88MP0002751_abnormal_autonomic_nervous1.03592268
89MP0001764_abnormal_homeostasis1.03550179
90MP0002653_abnormal_ependyma_morphology1.02786767
91MP0002277_abnormal_respiratory_mucosa1.02586383
92MP0002882_abnormal_neuron_morphology1.01107875
93MP0005187_abnormal_penis_morphology0.98870418
94MP0005535_abnormal_body_temperature0.98676769
95MP0002229_neurodegeneration0.97370294
96MP0002938_white_spotting0.96183433
97MP0003879_abnormal_hair_cell0.96003079
98MP0008569_lethality_at_weaning0.95606652
99MP0001664_abnormal_digestion0.94776160
100MP0003633_abnormal_nervous_system0.94102806
101MP0010329_abnormal_lipoprotein_level0.93830771
102MP0002066_abnormal_motor_capabilities/c0.93686987
103MP0005408_hypopigmentation0.93319223
104MP0003121_genomic_imprinting0.93189756
105MP0008058_abnormal_DNA_repair0.90669474
106MP0001324_abnormal_eye_pigmentation0.90216196
107MP0008260_abnormal_autophagy0.90120142
108MP0002095_abnormal_skin_pigmentation0.88996239
109MP0005389_reproductive_system_phenotype0.88110750
110MP0004147_increased_porphyrin_level0.87213080
111MP0000049_abnormal_middle_ear0.87180051
112MP0000955_abnormal_spinal_cord0.86765584
113MP0000681_abnormal_thyroid_gland0.86702324
114MP0005253_abnormal_eye_physiology0.86528009
115MP0000230_abnormal_systemic_arterial0.86453907
116MP0004215_abnormal_myocardial_fiber0.86423208
117MP0005410_abnormal_fertilization0.85053424
118MP0002160_abnormal_reproductive_system0.83816915
119MP0005636_abnormal_mineral_homeostasis0.83368311
120MP0002282_abnormal_trachea_morphology0.82782319
121MP0002822_catalepsy0.82766613
122MP0009764_decreased_sensitivity_to0.82505070
123MP0005075_abnormal_melanosome_morpholog0.76340206
124MP0002177_abnormal_outer_ear0.73557828
125MP0008789_abnormal_olfactory_epithelium0.72209225
126MP0003315_abnormal_perineum_morphology0.70641321
127MP0001346_abnormal_lacrimal_gland0.68142346
128MP0003787_abnormal_imprinting0.66682215
129MP0003634_abnormal_glial_cell0.66480504
130MP0008995_early_reproductive_senescence0.63173609
131MP0005394_taste/olfaction_phenotype0.61637892
132MP0005499_abnormal_olfactory_system0.61637892
133MP0005195_abnormal_posterior_eye0.60432164
134MP0002148_abnormal_hypersensitivity_rea0.59405247
135MP0002152_abnormal_brain_morphology0.57442964
136MP0005595_abnormal_vascular_smooth0.55605963
137MP0004811_abnormal_neuron_physiology0.55363823
138MP0002837_dystrophic_cardiac_calcinosis0.54610640

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)4.79437515
2Mitochondrial inheritance (HP:0001427)4.24667339
3Focal motor seizures (HP:0011153)4.13519433
4Abnormal mitochondria in muscle tissue (HP:0008316)4.09422663
5Progressive macrocephaly (HP:0004481)4.01659540
6Increased hepatocellular lipid droplets (HP:0006565)3.94640809
7Molar tooth sign on MRI (HP:0002419)3.84581556
8Abnormality of midbrain morphology (HP:0002418)3.84581556
9Renal Fanconi syndrome (HP:0001994)3.81947552
10Pancreatic cysts (HP:0001737)3.78957930
11Pancreatic fibrosis (HP:0100732)3.61099179
12Hypothermia (HP:0002045)3.60599921
13Acute encephalopathy (HP:0006846)3.55988942
143-Methylglutaconic aciduria (HP:0003535)3.54216738
15Absent/shortened dynein arms (HP:0200106)3.40096153
16Dynein arm defect of respiratory motile cilia (HP:0012255)3.40096153
17Increased CSF lactate (HP:0002490)3.37774187
18Hepatocellular necrosis (HP:0001404)3.37143251
19Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.31440981
20Nephronophthisis (HP:0000090)3.31124463
21Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.31039816
22Optic disc pallor (HP:0000543)3.29801745
23Lipid accumulation in hepatocytes (HP:0006561)3.25262524
24Parakeratosis (HP:0001036)3.17251742
25Abnormal ciliary motility (HP:0012262)3.10108139
26Retinal dysplasia (HP:0007973)3.01067373
27Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.94769171
28Abnormal respiratory epithelium morphology (HP:0012253)2.83432208
29Abnormal respiratory motile cilium morphology (HP:0005938)2.83432208
30Febrile seizures (HP:0002373)2.82865827
31Congenital, generalized hypertrichosis (HP:0004540)2.80233358
32Abnormality of the renal medulla (HP:0100957)2.78402833
33Abnormal respiratory motile cilium physiology (HP:0012261)2.77335796
34Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.77254854
35Type I transferrin isoform profile (HP:0003642)2.76741338
36Abnormality of the renal cortex (HP:0011035)2.63881129
37Abnormality of renal resorption (HP:0011038)2.63284512
38Hepatic necrosis (HP:0002605)2.61241579
39Type II lissencephaly (HP:0007260)2.60799016
40Congenital stationary night blindness (HP:0007642)2.56358673
41Abolished electroretinogram (ERG) (HP:0000550)2.53641144
42Exertional dyspnea (HP:0002875)2.50985414
43Medial flaring of the eyebrow (HP:0010747)2.50598710
44Abnormal hair whorl (HP:0010721)2.50063302
45Leukodystrophy (HP:0002415)2.47855452
46Increased intramyocellular lipid droplets (HP:0012240)2.47330332
47Polydipsia (HP:0001959)2.46272213
48Abnormal drinking behavior (HP:0030082)2.46272213
49Abnormality of the axillary hair (HP:0100134)2.42167737
50Abnormality of secondary sexual hair (HP:0009888)2.42167737
51Exercise intolerance (HP:0003546)2.39926041
52Severe visual impairment (HP:0001141)2.37191225
53Chronic hepatic failure (HP:0100626)2.35719583
54Split foot (HP:0001839)2.34749259
55Microvesicular hepatic steatosis (HP:0001414)2.33002290
56Absent rod-and cone-mediated responses on ERG (HP:0007688)2.31915918
57Patchy hypopigmentation of hair (HP:0011365)2.30923165
58Epileptic encephalopathy (HP:0200134)2.30865083
59Male pseudohermaphroditism (HP:0000037)2.27028255
60Limb dystonia (HP:0002451)2.26319563
61Abnormality of urine glucose concentration (HP:0011016)2.19751675
62Glycosuria (HP:0003076)2.19751675
63Cystic liver disease (HP:0006706)2.17703564
64Hyperventilation (HP:0002883)2.16865007
65White forelock (HP:0002211)2.16807355
66Atonic seizures (HP:0010819)2.15992109
67Sensory axonal neuropathy (HP:0003390)2.14957253
68Cerebral edema (HP:0002181)2.14567374
69Methylmalonic aciduria (HP:0012120)2.14534906
70Reduced antithrombin III activity (HP:0001976)2.14074146
71Nonprogressive disorder (HP:0003680)2.13942191
72Gait imbalance (HP:0002141)2.13707248
73Respiratory failure (HP:0002878)2.13600223
74Nasolacrimal duct obstruction (HP:0000579)2.11972470
75Tubular atrophy (HP:0000092)2.10748855
76Broad-based gait (HP:0002136)2.09040526
77True hermaphroditism (HP:0010459)2.08652821
78Lethargy (HP:0001254)2.07515690
79Renal cortical cysts (HP:0000803)2.07248029
80Nephrogenic diabetes insipidus (HP:0009806)2.06525385
81Sclerocornea (HP:0000647)2.04917260
82Stomach cancer (HP:0012126)2.04165403
83Lactic acidosis (HP:0003128)2.03656587
84Congenital primary aphakia (HP:0007707)2.03147262
85Thyroid-stimulating hormone excess (HP:0002925)2.02805170
86Myokymia (HP:0002411)2.02700739
87Polyphagia (HP:0002591)2.02123984
88Abnormality of alanine metabolism (HP:0010916)2.02068080
89Hyperalaninemia (HP:0003348)2.02068080
90Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.02068080
91Aplasia/Hypoplasia of the tongue (HP:0010295)2.01597057
92Polyuria (HP:0000103)2.00477823
93Aplasia/Hypoplasia of the tibia (HP:0005772)2.00047617
94CNS demyelination (HP:0007305)1.99658313
95Increased serum lactate (HP:0002151)1.98887778
96Furrowed tongue (HP:0000221)1.98078706
97Hyperglycinemia (HP:0002154)1.97570920
98Large for gestational age (HP:0001520)1.96586131
99Congenital hepatic fibrosis (HP:0002612)1.96240304
100Progressive inability to walk (HP:0002505)1.96230614
101Short tibia (HP:0005736)1.93804416
102Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.92642900
103Decreased activity of mitochondrial respiratory chain (HP:0008972)1.92642900
104Esotropia (HP:0000565)1.91974929
105Hemiparesis (HP:0001269)1.90263065
106Abnormality of aromatic amino acid family metabolism (HP:0004338)1.89794901
107Abnormal rod and cone electroretinograms (HP:0008323)1.88374254
108Occipital encephalocele (HP:0002085)1.87958528
109Aplasia/Hypoplasia of the lens (HP:0008063)1.87420287
110Methylmalonic acidemia (HP:0002912)1.87417379
111Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.86903238
112Abnormal protein N-linked glycosylation (HP:0012347)1.86903238
113Abnormal protein glycosylation (HP:0012346)1.86903238
114Abnormal glycosylation (HP:0012345)1.86903238
115Focal seizures (HP:0007359)1.86691984
116Vaginal atresia (HP:0000148)1.86406610
117Aplasia cutis congenita (HP:0001057)1.85839645
118X-linked dominant inheritance (HP:0001423)1.85813217
119Abnormality of glycolysis (HP:0004366)1.85246508
120Increased serum pyruvate (HP:0003542)1.85246508
121Decreased central vision (HP:0007663)1.84935358
122Attenuation of retinal blood vessels (HP:0007843)1.84554980
123Renal tubular dysfunction (HP:0000124)1.84458984
124Hyperphosphaturia (HP:0003109)1.83968303
125Respiratory difficulties (HP:0002880)1.83109057
126Abnormality of the lacrimal duct (HP:0011481)1.82847068
127Abnormal number of erythroid precursors (HP:0012131)1.82498760
128Delayed CNS myelination (HP:0002188)1.82354315
129Genital tract atresia (HP:0001827)1.82051909
130Abnormality of the phalanges of the 2nd finger (HP:0009541)1.82021376
131Hypomagnesemia (HP:0002917)1.78842034
132Increased muscle lipid content (HP:0009058)1.78706515
133Metaphyseal dysplasia (HP:0100255)1.78469801
134Postaxial foot polydactyly (HP:0001830)1.78022363
135Type 2 muscle fiber atrophy (HP:0003554)1.77793080
136Septo-optic dysplasia (HP:0100842)1.77467212
137Abnormality of cells of the erythroid lineage (HP:0012130)1.77280622
138Progressive cerebellar ataxia (HP:0002073)1.76776766
139Dialeptic seizures (HP:0011146)1.76079157
140Anencephaly (HP:0002323)1.76048365
141Ketoacidosis (HP:0001993)1.75169160
142Abnormal pupillary function (HP:0007686)1.75117362
143Rhinitis (HP:0012384)1.74987839
144Abnormality of the nasolacrimal system (HP:0000614)1.74171894
145Decreased electroretinogram (ERG) amplitude (HP:0000654)1.71375398
146Generalized tonic-clonic seizures (HP:0002069)1.71227136
147Tubulointerstitial nephritis (HP:0001970)1.70218359
148Absence seizures (HP:0002121)1.69926258

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK4.75574930
2TNIK3.55894405
3FRK3.52329909
4STK163.23672024
5MAP4K22.88924037
6MAP2K72.61714719
7MUSK2.58256603
8MAP3K122.27648190
9ZAK2.20371456
10STK392.12339719
11MKNK21.99124800
12WNK31.99072488
13NUAK11.83444880
14NTRK31.81752687
15TAOK31.80791944
16NME11.77370406
17PNCK1.76596722
18GRK71.73534953
19OXSR11.73220815
20ADRBK21.68667881
21CDK191.67040726
22ERBB31.63505296
23TRIM281.62502033
24BMPR1B1.60665144
25TLK11.57311313
26BCKDK1.56937638
27EPHA41.56406438
28FES1.55467226
29VRK21.54372990
30MAPK131.51739181
31GRK51.45218481
32BLK1.41113102
33NME21.41015207
34MKNK11.40838672
35BMPR21.32617354
36PKN11.28307243
37MAPKAPK51.24455935
38IRAK21.21427980
39PRPF4B1.20918338
40MST41.20732865
41CAMK2B1.20442392
42RIPK41.19679425
43INSRR1.17983677
44EIF2AK31.16078369
45UHMK11.15990459
46CAMKK21.13360318
47MAPKAPK31.09173936
48PBK1.09077293
49PAK31.09029275
50BCR1.07998087
51IRAK11.05991502
52MARK11.04809918
53VRK11.04429909
54BRSK21.02203737
55ARAF1.01005941
56MAP3K41.00127942
57NEK60.99839399
58SRPK10.99040090
59YES10.98780609
60ACVR1B0.98289480
61WNK40.96489072
62CAMK2A0.96328822
63MYLK0.95689710
64MAPK150.95244475
65WEE10.94908404
66TNK20.94296308
67PLK20.91633673
68SIK30.91474271
69FGR0.91157928
70CDK30.90678582
71DAPK20.90042417
72EIF2AK20.89475979
73TIE10.87247262
74IRAK40.86287336
75CAMK10.86112365
76TXK0.86036450
77CAMK2D0.84861440
78PRKCE0.84501146
79DYRK20.81756109
80CSNK1G30.79711369
81DYRK1A0.78603200
82DYRK30.74026291
83NTRK20.72838866
84PIM20.72416424
85FGFR20.71611624
86EPHB20.68366519
87ADRBK10.67616290
88CCNB10.66415087
89TEC0.66323046
90CLK10.64959486
91GRK10.64769505
92MAP2K60.64747480
93CAMK2G0.62396883
94PASK0.61908586
95IRAK30.61722344
96MARK30.61365814
97CSNK1G10.60621941
98ABL20.60115099
99TGFBR10.58360665
100BRAF0.58314232
101PLK30.56720634
102PRKCG0.55364787
103CSNK1G20.54149534
104CDK50.53339120
105MINK10.53115465
106IKBKB0.51942846
107PRKACA0.50111661
108LIMK10.49112079
109SYK0.47594959
110NLK0.45981677
111STK38L0.45877275
112PRKG10.45527713
113PINK10.43906847
114LYN0.43669025
115PRKCA0.42719258
116OBSCN0.41709867
117RPS6KA40.40799973
118CSNK1A1L0.39315675
119MAPK40.39060715
120HIPK20.38566272
121MAP2K40.37969726
122KIT0.37157897
123PIK3CA0.37001265
124STK110.36554303
125CSNK1A10.36092822
126PHKG10.35610785
127PHKG20.35610785
128ROCK20.35596614
129PLK40.35511286
130CDK80.35341611
131PRKCQ0.35113791
132PRKD20.35110885
133RPS6KA50.35099070
134PRKACB0.35018217
135PTK2B0.34281012
136IGF1R0.33478900

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001904.75147207
2Parkinsons disease_Homo sapiens_hsa050123.71592278
3Protein export_Homo sapiens_hsa030603.21887692
4Alzheimers disease_Homo sapiens_hsa050103.09182618
5Nicotine addiction_Homo sapiens_hsa050332.95983351
6Ribosome_Homo sapiens_hsa030102.71119129
7Huntingtons disease_Homo sapiens_hsa050162.60155842
8Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.18500385
9Collecting duct acid secretion_Homo sapiens_hsa049662.16728642
10Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.11580158
11Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.97154598
12Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.91300692
13Phototransduction_Homo sapiens_hsa047441.90059629
14Taste transduction_Homo sapiens_hsa047421.86288043
15Butanoate metabolism_Homo sapiens_hsa006501.84548682
16Serotonergic synapse_Homo sapiens_hsa047261.83491152
17Cardiac muscle contraction_Homo sapiens_hsa042601.80442706
18Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.79427348
19RNA polymerase_Homo sapiens_hsa030201.77649919
20Primary bile acid biosynthesis_Homo sapiens_hsa001201.73094118
21Morphine addiction_Homo sapiens_hsa050321.72304861
22Proteasome_Homo sapiens_hsa030501.66466099
23Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.64199059
24Tryptophan metabolism_Homo sapiens_hsa003801.63608412
25Fatty acid elongation_Homo sapiens_hsa000621.61738148
26Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.60600860
27GABAergic synapse_Homo sapiens_hsa047271.60546398
28Glutamatergic synapse_Homo sapiens_hsa047241.50908427
29Peroxisome_Homo sapiens_hsa041461.49526974
30Propanoate metabolism_Homo sapiens_hsa006401.49412898
31Chemical carcinogenesis_Homo sapiens_hsa052041.46699164
32Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.45185651
33SNARE interactions in vesicular transport_Homo sapiens_hsa041301.43935471
34Synaptic vesicle cycle_Homo sapiens_hsa047211.42538886
35Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.40561703
36Caffeine metabolism_Homo sapiens_hsa002321.39692540
37Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.37133165
38Olfactory transduction_Homo sapiens_hsa047401.35847786
39Vibrio cholerae infection_Homo sapiens_hsa051101.35767339
40Steroid hormone biosynthesis_Homo sapiens_hsa001401.33290455
41Ether lipid metabolism_Homo sapiens_hsa005651.33106337
42Circadian entrainment_Homo sapiens_hsa047131.31667681
43Sphingolipid metabolism_Homo sapiens_hsa006001.29243548
44Nitrogen metabolism_Homo sapiens_hsa009101.28452097
45Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.26729221
46Rheumatoid arthritis_Homo sapiens_hsa053231.22466074
47Amphetamine addiction_Homo sapiens_hsa050311.17567192
48Arachidonic acid metabolism_Homo sapiens_hsa005901.10581250
49Calcium signaling pathway_Homo sapiens_hsa040201.08568592
50Retinol metabolism_Homo sapiens_hsa008301.05881563
51Long-term depression_Homo sapiens_hsa047301.05844243
52Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.05231803
53Fatty acid degradation_Homo sapiens_hsa000711.01770813
54Salivary secretion_Homo sapiens_hsa049700.96102701
55Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.93881793
56Cocaine addiction_Homo sapiens_hsa050300.93852275
57Dopaminergic synapse_Homo sapiens_hsa047280.93652565
58Autoimmune thyroid disease_Homo sapiens_hsa053200.93606791
59Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.91664614
60Insulin secretion_Homo sapiens_hsa049110.88185616
61Graft-versus-host disease_Homo sapiens_hsa053320.87440126
62Linoleic acid metabolism_Homo sapiens_hsa005910.86648964
63Steroid biosynthesis_Homo sapiens_hsa001000.85987636
64beta-Alanine metabolism_Homo sapiens_hsa004100.84097824
65Sulfur metabolism_Homo sapiens_hsa009200.83932817
66Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.83031538
67Purine metabolism_Homo sapiens_hsa002300.81922202
68Pentose and glucuronate interconversions_Homo sapiens_hsa000400.80987820
69Basal transcription factors_Homo sapiens_hsa030220.80227667
70Cholinergic synapse_Homo sapiens_hsa047250.79886277
71Renin secretion_Homo sapiens_hsa049240.79451031
72Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.79325091
73Long-term potentiation_Homo sapiens_hsa047200.79294565
74Folate biosynthesis_Homo sapiens_hsa007900.77351317
75Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.75424653
76Pyrimidine metabolism_Homo sapiens_hsa002400.75208856
77Glutathione metabolism_Homo sapiens_hsa004800.74644796
78Axon guidance_Homo sapiens_hsa043600.73801863
79Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.73775374
80RNA degradation_Homo sapiens_hsa030180.73494748
81Fanconi anemia pathway_Homo sapiens_hsa034600.70736033
82Allograft rejection_Homo sapiens_hsa053300.70692228
83Histidine metabolism_Homo sapiens_hsa003400.70685276
84Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.70530147
85Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.69045149
86Homologous recombination_Homo sapiens_hsa034400.65901043
87Phagosome_Homo sapiens_hsa041450.64866848
88Asthma_Homo sapiens_hsa053100.64697209
89Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.64134717
90Fatty acid metabolism_Homo sapiens_hsa012120.62544123
91Regulation of autophagy_Homo sapiens_hsa041400.62355825
92Selenocompound metabolism_Homo sapiens_hsa004500.60285933
93Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.59743254
94alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.59550434
95Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.59238793
96Metabolic pathways_Homo sapiens_hsa011000.57406892
97Vascular smooth muscle contraction_Homo sapiens_hsa042700.56843818
98Circadian rhythm_Homo sapiens_hsa047100.56798692
99Other glycan degradation_Homo sapiens_hsa005110.52431012
100Type I diabetes mellitus_Homo sapiens_hsa049400.52340484
101Staphylococcus aureus infection_Homo sapiens_hsa051500.52097738
102Mineral absorption_Homo sapiens_hsa049780.50203542
103Aldosterone synthesis and secretion_Homo sapiens_hsa049250.49696044
104African trypanosomiasis_Homo sapiens_hsa051430.49222938
105Pyruvate metabolism_Homo sapiens_hsa006200.49183380
106Non-homologous end-joining_Homo sapiens_hsa034500.47549662
107Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.47458993
108Phenylalanine metabolism_Homo sapiens_hsa003600.45794994
109cAMP signaling pathway_Homo sapiens_hsa040240.45201813
110Oxytocin signaling pathway_Homo sapiens_hsa049210.45071046
111Nucleotide excision repair_Homo sapiens_hsa034200.44731257
112Gastric acid secretion_Homo sapiens_hsa049710.44269451
113Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.43296107
114Maturity onset diabetes of the young_Homo sapiens_hsa049500.43175377
115ABC transporters_Homo sapiens_hsa020100.43151826
116Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.42885954
117Complement and coagulation cascades_Homo sapiens_hsa046100.42641995
118Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.41483837
119Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.41232735
120Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.39543623
121Drug metabolism - other enzymes_Homo sapiens_hsa009830.38666301
122Ovarian steroidogenesis_Homo sapiens_hsa049130.38387053
123PPAR signaling pathway_Homo sapiens_hsa033200.37772399
124Alcoholism_Homo sapiens_hsa050340.36002190
125Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.34178698
126Hematopoietic cell lineage_Homo sapiens_hsa046400.32919171
127Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.32482523
128Pancreatic secretion_Homo sapiens_hsa049720.31524060
129Ras signaling pathway_Homo sapiens_hsa040140.31097567
130Melanogenesis_Homo sapiens_hsa049160.30811362
131Primary immunodeficiency_Homo sapiens_hsa053400.29245087
132Tyrosine metabolism_Homo sapiens_hsa003500.27799908
133Gap junction_Homo sapiens_hsa045400.27042024
134N-Glycan biosynthesis_Homo sapiens_hsa005100.25860214
135Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.25759343
136Intestinal immune network for IgA production_Homo sapiens_hsa046720.23812652
137Malaria_Homo sapiens_hsa051440.23549298
138Wnt signaling pathway_Homo sapiens_hsa043100.20796986

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