

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 6.27299982 |
| 2 | behavioral response to nicotine (GO:0035095) | 5.58156246 |
| 3 | indolalkylamine metabolic process (GO:0006586) | 5.31886761 |
| 4 | indole-containing compound catabolic process (GO:0042436) | 5.13995301 |
| 5 | indolalkylamine catabolic process (GO:0046218) | 5.13995301 |
| 6 | tryptophan catabolic process (GO:0006569) | 5.13995301 |
| 7 | kynurenine metabolic process (GO:0070189) | 5.13319351 |
| 8 | regulation of posttranscriptional gene silencing (GO:0060147) | 4.85441493 |
| 9 | regulation of gene silencing by miRNA (GO:0060964) | 4.85441493 |
| 10 | regulation of gene silencing by RNA (GO:0060966) | 4.85441493 |
| 11 | L-fucose catabolic process (GO:0042355) | 4.34124269 |
| 12 | fucose catabolic process (GO:0019317) | 4.34124269 |
| 13 | L-fucose metabolic process (GO:0042354) | 4.34124269 |
| 14 | tryptophan metabolic process (GO:0006568) | 4.27114394 |
| 15 | indole-containing compound metabolic process (GO:0042430) | 4.02450087 |
| 16 | cellular biogenic amine catabolic process (GO:0042402) | 4.00809842 |
| 17 | amine catabolic process (GO:0009310) | 4.00809842 |
| 18 | epithelial cilium movement (GO:0003351) | 3.95756911 |
| 19 | mannosylation (GO:0097502) | 3.95066789 |
| 20 | nucleotide transmembrane transport (GO:1901679) | 3.93266599 |
| 21 | autophagic vacuole fusion (GO:0000046) | 3.93072590 |
| 22 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.80366510 |
| 23 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.80366510 |
| 24 | NADH dehydrogenase complex assembly (GO:0010257) | 3.80366510 |
| 25 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.76613886 |
| 26 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.76613886 |
| 27 | pyrimidine-containing compound transmembrane transport (GO:0072531) | 3.59140457 |
| 28 | rRNA catabolic process (GO:0016075) | 3.57393234 |
| 29 | signal peptide processing (GO:0006465) | 3.52857206 |
| 30 | protein complex biogenesis (GO:0070271) | 3.52820390 |
| 31 | respiratory chain complex IV assembly (GO:0008535) | 3.48364325 |
| 32 | pyrimidine dimer repair (GO:0006290) | 3.46918469 |
| 33 | kidney morphogenesis (GO:0060993) | 3.44239506 |
| 34 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.31006605 |
| 35 | negative regulation of telomere maintenance (GO:0032205) | 3.26627093 |
| 36 | cell proliferation in forebrain (GO:0021846) | 3.23977830 |
| 37 | cilium movement (GO:0003341) | 3.22821283 |
| 38 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.19930171 |
| 39 | male meiosis I (GO:0007141) | 3.18025025 |
| 40 | serotonin metabolic process (GO:0042428) | 3.16370526 |
| 41 | behavioral response to ethanol (GO:0048149) | 3.13550766 |
| 42 | regulation of hippo signaling (GO:0035330) | 3.08226418 |
| 43 | cytochrome complex assembly (GO:0017004) | 3.04358605 |
| 44 | pyrimidine nucleobase catabolic process (GO:0006208) | 3.03663055 |
| 45 | cardiovascular system development (GO:0072358) | 3.01096730 |
| 46 | regulation of respiratory system process (GO:0044065) | 2.98816226 |
| 47 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.97742217 |
| 48 | appendage development (GO:0048736) | 2.90688649 |
| 49 | limb development (GO:0060173) | 2.90688649 |
| 50 | detection of light stimulus involved in visual perception (GO:0050908) | 2.90142157 |
| 51 | detection of light stimulus involved in sensory perception (GO:0050962) | 2.90142157 |
| 52 | primary amino compound metabolic process (GO:1901160) | 2.89163027 |
| 53 | axonemal dynein complex assembly (GO:0070286) | 2.88284553 |
| 54 | acrosome assembly (GO:0001675) | 2.86184660 |
| 55 | photoreceptor cell maintenance (GO:0045494) | 2.85874654 |
| 56 | cellular response to exogenous dsRNA (GO:0071360) | 2.82796746 |
| 57 | nonmotile primary cilium assembly (GO:0035058) | 2.82559313 |
| 58 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 2.82423152 |
| 59 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:004316 | 2.78836670 |
| 60 | organelle membrane fusion (GO:0090174) | 2.78317965 |
| 61 | aromatic amino acid family catabolic process (GO:0009074) | 2.77681123 |
| 62 | regulation of hydrogen peroxide metabolic process (GO:0010310) | 2.77660040 |
| 63 | base-excision repair, AP site formation (GO:0006285) | 2.67248662 |
| 64 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.66080105 |
| 65 | negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948) | 2.65904909 |
| 66 | nucleobase catabolic process (GO:0046113) | 2.65457821 |
| 67 | recombinational repair (GO:0000725) | 2.64551140 |
| 68 | startle response (GO:0001964) | 2.64047396 |
| 69 | negative regulation of reactive oxygen species metabolic process (GO:2000378) | 2.63215446 |
| 70 | oxidative demethylation (GO:0070989) | 2.62859581 |
| 71 | amino acid salvage (GO:0043102) | 2.59782477 |
| 72 | L-methionine salvage (GO:0071267) | 2.59782477 |
| 73 | L-methionine biosynthetic process (GO:0071265) | 2.59782477 |
| 74 | positive regulation of Notch signaling pathway (GO:0045747) | 2.59411415 |
| 75 | forebrain neuron differentiation (GO:0021879) | 2.58487659 |
| 76 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.58374240 |
| 77 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.58374240 |
| 78 | regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095) | 2.58057056 |
| 79 | double-strand break repair via homologous recombination (GO:0000724) | 2.58046957 |
| 80 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 2.57750434 |
| 81 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.57209184 |
| 82 | benzene-containing compound metabolic process (GO:0042537) | 2.56636118 |
| 83 | protein K63-linked ubiquitination (GO:0070534) | 2.56117638 |
| 84 | peptidyl-histidine modification (GO:0018202) | 2.54332388 |
| 85 | ovulation cycle (GO:0042698) | 2.52740266 |
| 86 | positive regulation of defense response to virus by host (GO:0002230) | 2.52707087 |
| 87 | positive regulation of microtubule polymerization (GO:0031116) | 2.52593084 |
| 88 | phosphatidylinositol acyl-chain remodeling (GO:0036149) | 2.52191302 |
| 89 | aromatic amino acid family metabolic process (GO:0009072) | 2.50362273 |
| 90 | respiratory tube development (GO:0030323) | 2.49189560 |
| 91 | negative regulation of systemic arterial blood pressure (GO:0003085) | 2.48781859 |
| 92 | pseudouridine synthesis (GO:0001522) | 2.47476480 |
| 93 | chromatin remodeling at centromere (GO:0031055) | 2.47321922 |
| 94 | cellular biogenic amine biosynthetic process (GO:0042401) | 2.47267583 |
| 95 | lysosome localization (GO:0032418) | 2.46600054 |
| 96 | protein K6-linked ubiquitination (GO:0085020) | 2.45433354 |
| 97 | regulation of rhodopsin mediated signaling pathway (GO:0022400) | 2.43855467 |
| 98 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.43830533 |
| 99 | NAD biosynthetic process (GO:0009435) | 2.43712932 |
| 100 | cell morphogenesis involved in neuron differentiation (GO:0048667) | 2.43523311 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.93679424 |
| 2 | VDR_22108803_ChIP-Seq_LS180_Human | 3.79912569 |
| 3 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.79454000 |
| 4 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.78892159 |
| 5 | IRF1_19129219_ChIP-ChIP_H3396_Human | 3.31879921 |
| 6 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.78311600 |
| 7 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.63695872 |
| 8 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.59916729 |
| 9 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.26807944 |
| 10 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.94294154 |
| 11 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.91428989 |
| 12 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.91282685 |
| 13 | EWS_26573619_Chip-Seq_HEK293_Human | 1.91186557 |
| 14 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.88243111 |
| 15 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.84454426 |
| 16 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.80520825 |
| 17 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.75832490 |
| 18 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.72748324 |
| 19 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.72104273 |
| 20 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.70647397 |
| 21 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.68543639 |
| 22 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.66760608 |
| 23 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.66641593 |
| 24 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.59429774 |
| 25 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.59429774 |
| 26 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.50770649 |
| 27 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.48651385 |
| 28 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.46683294 |
| 29 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.40524838 |
| 30 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.39548398 |
| 31 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.36103200 |
| 32 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.35732180 |
| 33 | ERA_21632823_ChIP-Seq_H3396_Human | 1.34078715 |
| 34 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.32757528 |
| 35 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.30746735 |
| 36 | TP53_16413492_ChIP-PET_HCT116_Human | 1.29665561 |
| 37 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.28047894 |
| 38 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.26611607 |
| 39 | P300_19829295_ChIP-Seq_ESCs_Human | 1.25537191 |
| 40 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.24613867 |
| 41 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.24479350 |
| 42 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.24111503 |
| 43 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.24111503 |
| 44 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.21047250 |
| 45 | FUS_26573619_Chip-Seq_HEK293_Human | 1.20462353 |
| 46 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.18682643 |
| 47 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.18682643 |
| 48 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.15823743 |
| 49 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.15823743 |
| 50 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.15571833 |
| 51 | STAT3_23295773_ChIP-Seq_U87_Human | 1.13495530 |
| 52 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.13063493 |
| 53 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.12707856 |
| 54 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.12090602 |
| 55 | AR_20517297_ChIP-Seq_VCAP_Human | 1.12089994 |
| 56 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.11653673 |
| 57 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.11440907 |
| 58 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.11304110 |
| 59 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.11027604 |
| 60 | OCT4_20526341_ChIP-Seq_ESCs_Human | 1.09821121 |
| 61 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.08501237 |
| 62 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.08171721 |
| 63 | NCOR_22424771_ChIP-Seq_293T_Human | 1.07616438 |
| 64 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.06719078 |
| 65 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 1.06625406 |
| 66 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.04934705 |
| 67 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.04441943 |
| 68 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.04057552 |
| 69 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.03080528 |
| 70 | RBPJ_21746931_ChIP-Seq_IB4_Human | 1.02857286 |
| 71 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.99690277 |
| 72 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.98169271 |
| 73 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.97526712 |
| 74 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.97476113 |
| 75 | GATA3_26560356_Chip-Seq_TH1_Human | 0.96018482 |
| 76 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.95066849 |
| 77 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 0.95056786 |
| 78 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 0.93972902 |
| 79 | TCF4_23295773_ChIP-Seq_U87_Human | 0.93566115 |
| 80 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.93502254 |
| 81 | DROSHA_22980978_ChIP-Seq_HELA_Human | 0.92452585 |
| 82 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 0.92290486 |
| 83 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.92132602 |
| 84 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.91755791 |
| 85 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.91187406 |
| 86 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.90994307 |
| 87 | ETV1_20927104_ChIP-Seq_GIST48_Human | 0.90665533 |
| 88 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.90533023 |
| 89 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 0.90486495 |
| 90 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.90484581 |
| 91 | AR_25329375_ChIP-Seq_VCAP_Human | 0.89272319 |
| 92 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 0.88797951 |
| 93 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.88557830 |
| 94 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.88117440 |
| 95 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.87982789 |
| 96 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.87635116 |
| 97 | P300_27268052_Chip-Seq_Bcells_Human | 0.86256146 |
| 98 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.85599550 |
| 99 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.85526410 |
| 100 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 0.85123694 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0006292_abnormal_olfactory_placode | 4.45347196 |
| 2 | MP0003646_muscle_fatigue | 3.83961237 |
| 3 | MP0008057_abnormal_DNA_replication | 3.38465924 |
| 4 | MP0002736_abnormal_nociception_after | 2.65409719 |
| 5 | MP0002653_abnormal_ependyma_morphology | 2.45874972 |
| 6 | MP0001501_abnormal_sleep_pattern | 2.44294105 |
| 7 | MP0004147_increased_porphyrin_level | 2.35861148 |
| 8 | MP0004043_abnormal_pH_regulation | 2.29480531 |
| 9 | MP0001293_anophthalmia | 2.28449654 |
| 10 | MP0008877_abnormal_DNA_methylation | 2.26996578 |
| 11 | MP0004133_heterotaxia | 2.18182008 |
| 12 | MP0001968_abnormal_touch/_nociception | 2.16274826 |
| 13 | MP0002876_abnormal_thyroid_physiology | 2.01356455 |
| 14 | MP0004130_abnormal_muscle_cell | 1.99748125 |
| 15 | MP0002938_white_spotting | 1.91849252 |
| 16 | MP0000569_abnormal_digit_pigmentation | 1.90126977 |
| 17 | MP0006276_abnormal_autonomic_nervous | 1.86422197 |
| 18 | MP0005266_abnormal_metabolism | 1.85407143 |
| 19 | MP0005551_abnormal_eye_electrophysiolog | 1.82401274 |
| 20 | MP0004142_abnormal_muscle_tone | 1.79684385 |
| 21 | MP0000427_abnormal_hair_cycle | 1.74078932 |
| 22 | MP0001485_abnormal_pinna_reflex | 1.74037949 |
| 23 | MP0002638_abnormal_pupillary_reflex | 1.71235362 |
| 24 | MP0003195_calcinosis | 1.70818791 |
| 25 | MP0003136_yellow_coat_color | 1.70534089 |
| 26 | MP0009053_abnormal_anal_canal | 1.68975254 |
| 27 | MP0008961_abnormal_basal_metabolism | 1.67853750 |
| 28 | MP0006072_abnormal_retinal_apoptosis | 1.67138400 |
| 29 | MP0003693_abnormal_embryo_hatching | 1.63198978 |
| 30 | MP0008789_abnormal_olfactory_epithelium | 1.58472924 |
| 31 | MP0000631_abnormal_neuroendocrine_gland | 1.57884173 |
| 32 | MP0009046_muscle_twitch | 1.57234656 |
| 33 | MP0009745_abnormal_behavioral_response | 1.51946960 |
| 34 | MP0008872_abnormal_physiological_respon | 1.51016872 |
| 35 | MP0009379_abnormal_foot_pigmentation | 1.48772737 |
| 36 | MP0008995_early_reproductive_senescence | 1.47669577 |
| 37 | MP0003011_delayed_dark_adaptation | 1.47348454 |
| 38 | MP0004233_abnormal_muscle_weight | 1.41731548 |
| 39 | MP0004145_abnormal_muscle_electrophysio | 1.39161230 |
| 40 | MP0002272_abnormal_nervous_system | 1.33572064 |
| 41 | MP0003137_abnormal_impulse_conducting | 1.33347166 |
| 42 | MP0002735_abnormal_chemical_nociception | 1.29590402 |
| 43 | MP0003252_abnormal_bile_duct | 1.29289881 |
| 44 | MP0004742_abnormal_vestibular_system | 1.25776353 |
| 45 | MP0002009_preneoplasia | 1.25129748 |
| 46 | MP0005645_abnormal_hypothalamus_physiol | 1.17922343 |
| 47 | MP0002557_abnormal_social/conspecific_i | 1.16464681 |
| 48 | MP0003121_genomic_imprinting | 1.16089561 |
| 49 | MP0002572_abnormal_emotion/affect_behav | 1.15123650 |
| 50 | MP0001919_abnormal_reproductive_system | 1.13432570 |
| 51 | MP0005499_abnormal_olfactory_system | 1.12012599 |
| 52 | MP0005394_taste/olfaction_phenotype | 1.12012599 |
| 53 | MP0000566_synostosis | 1.02897850 |
| 54 | MP0002233_abnormal_nose_morphology | 1.02782384 |
| 55 | MP0002254_reproductive_system_inflammat | 1.01348446 |
| 56 | MP0002067_abnormal_sensory_capabilities | 1.00201002 |
| 57 | MP0005195_abnormal_posterior_eye | 0.99921792 |
| 58 | MP0002064_seizures | 0.97775347 |
| 59 | MP0002733_abnormal_thermal_nociception | 0.97329403 |
| 60 | MP0005253_abnormal_eye_physiology | 0.97316381 |
| 61 | MP0002277_abnormal_respiratory_mucosa | 0.97261159 |
| 62 | MP0003937_abnormal_limbs/digits/tail_de | 0.97052546 |
| 63 | MP0002184_abnormal_innervation | 0.96652404 |
| 64 | MP0003959_abnormal_lean_body | 0.92734008 |
| 65 | MP0005085_abnormal_gallbladder_physiolo | 0.92250722 |
| 66 | MP0002752_abnormal_somatic_nervous | 0.91413928 |
| 67 | MP0000647_abnormal_sebaceous_gland | 0.90660876 |
| 68 | MP0003890_abnormal_embryonic-extraembry | 0.90563755 |
| 69 | MP0001970_abnormal_pain_threshold | 0.88775475 |
| 70 | MP0005167_abnormal_blood-brain_barrier | 0.88450748 |
| 71 | MP0001486_abnormal_startle_reflex | 0.86749717 |
| 72 | MP0002332_abnormal_exercise_endurance | 0.84996431 |
| 73 | MP0005670_abnormal_white_adipose | 0.84838608 |
| 74 | MP0005391_vision/eye_phenotype | 0.83801833 |
| 75 | MP0006035_abnormal_mitochondrial_morpho | 0.83116592 |
| 76 | MP0003315_abnormal_perineum_morphology | 0.82361711 |
| 77 | MP0001986_abnormal_taste_sensitivity | 0.81839092 |
| 78 | MP0001873_stomach_inflammation | 0.81825717 |
| 79 | MP0000383_abnormal_hair_follicle | 0.79917066 |
| 80 | MP0002210_abnormal_sex_determination | 0.79170180 |
| 81 | MP0003718_maternal_effect | 0.78946623 |
| 82 | MP0000955_abnormal_spinal_cord | 0.78775351 |
| 83 | MP0000470_abnormal_stomach_morphology | 0.77730333 |
| 84 | MP0010329_abnormal_lipoprotein_level | 0.77374418 |
| 85 | MP0003638_abnormal_response/metabolism_ | 0.77293496 |
| 86 | MP0003763_abnormal_thymus_physiology | 0.77282421 |
| 87 | MP0002160_abnormal_reproductive_system | 0.76757314 |
| 88 | MP0005389_reproductive_system_phenotype | 0.76692370 |
| 89 | MP0010030_abnormal_orbit_morphology | 0.76490662 |
| 90 | MP0004859_abnormal_synaptic_plasticity | 0.75744061 |
| 91 | MP0003698_abnormal_male_reproductive | 0.74754996 |
| 92 | MP0000372_irregular_coat_pigmentation | 0.74666153 |
| 93 | MP0005423_abnormal_somatic_nervous | 0.73346399 |
| 94 | MP0001348_abnormal_lacrimal_gland | 0.73319247 |
| 95 | MP0001270_distended_abdomen | 0.73038632 |
| 96 | MP0002089_abnormal_postnatal_growth/wei | 0.71947402 |
| 97 | MP0001905_abnormal_dopamine_level | 0.71909081 |
| 98 | MP0002063_abnormal_learning/memory/cond | 0.71855196 |
| 99 | MP0003635_abnormal_synaptic_transmissio | 0.71002369 |
| 100 | MP0001929_abnormal_gametogenesis | 0.70303903 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Pancreatic cysts (HP:0001737) | 4.79292787 |
| 2 | Pancreatic fibrosis (HP:0100732) | 4.78852344 |
| 3 | True hermaphroditism (HP:0010459) | 3.74095354 |
| 4 | Cystic liver disease (HP:0006706) | 3.45367133 |
| 5 | Tubular atrophy (HP:0000092) | 3.44632085 |
| 6 | Abolished electroretinogram (ERG) (HP:0000550) | 3.18669037 |
| 7 | Pendular nystagmus (HP:0012043) | 3.14792170 |
| 8 | Congenital stationary night blindness (HP:0007642) | 3.14288463 |
| 9 | Congenital, generalized hypertrichosis (HP:0004540) | 3.01653073 |
| 10 | Hypoplastic ischia (HP:0003175) | 3.00971019 |
| 11 | Rib fusion (HP:0000902) | 2.95919914 |
| 12 | Clumsiness (HP:0002312) | 2.88328508 |
| 13 | Hypoplasia of the pons (HP:0012110) | 2.85211518 |
| 14 | Sclerocornea (HP:0000647) | 2.82790096 |
| 15 | Nephronophthisis (HP:0000090) | 2.81205279 |
| 16 | Patellar aplasia (HP:0006443) | 2.79529836 |
| 17 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 2.76424865 |
| 18 | Inability to walk (HP:0002540) | 2.76112165 |
| 19 | Progressive inability to walk (HP:0002505) | 2.74693228 |
| 20 | Abnormality of the renal medulla (HP:0100957) | 2.65658313 |
| 21 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.64142426 |
| 22 | Protruding tongue (HP:0010808) | 2.62879664 |
| 23 | Abnormality of the pubic bones (HP:0003172) | 2.57944225 |
| 24 | Abnormality of the pons (HP:0007361) | 2.57561734 |
| 25 | Chronic hepatic failure (HP:0100626) | 2.57440317 |
| 26 | Molar tooth sign on MRI (HP:0002419) | 2.56644151 |
| 27 | Abnormality of midbrain morphology (HP:0002418) | 2.56644151 |
| 28 | Asplenia (HP:0001746) | 2.56610500 |
| 29 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.56532724 |
| 30 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.56126722 |
| 31 | Type II lissencephaly (HP:0007260) | 2.55590369 |
| 32 | Large for gestational age (HP:0001520) | 2.45503413 |
| 33 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.45086209 |
| 34 | Reticulocytopenia (HP:0001896) | 2.42208997 |
| 35 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.39227012 |
| 36 | Abnormality of the ischium (HP:0003174) | 2.38841943 |
| 37 | Chromsome breakage (HP:0040012) | 2.35700964 |
| 38 | Genetic anticipation (HP:0003743) | 2.32495102 |
| 39 | Prominent supraorbital ridges (HP:0000336) | 2.31432827 |
| 40 | Abnormality of the renal cortex (HP:0011035) | 2.30991773 |
| 41 | Anencephaly (HP:0002323) | 2.30029054 |
| 42 | Hyperglycinuria (HP:0003108) | 2.29373214 |
| 43 | Supernumerary spleens (HP:0009799) | 2.27418125 |
| 44 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.24628631 |
| 45 | Abnormal number of erythroid precursors (HP:0012131) | 2.20986431 |
| 46 | Anterior segment dysgenesis (HP:0007700) | 2.20409981 |
| 47 | Hepatocellular necrosis (HP:0001404) | 2.18026632 |
| 48 | Abnormal ciliary motility (HP:0012262) | 2.17052706 |
| 49 | Congenital hepatic fibrosis (HP:0002612) | 2.15882272 |
| 50 | Renal dysplasia (HP:0000110) | 2.14807824 |
| 51 | Attenuation of retinal blood vessels (HP:0007843) | 2.14572877 |
| 52 | Hepatic necrosis (HP:0002605) | 2.12914304 |
| 53 | Cerebellar dysplasia (HP:0007033) | 2.11384129 |
| 54 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.11052371 |
| 55 | Duplicated collecting system (HP:0000081) | 2.08042040 |
| 56 | Bile duct proliferation (HP:0001408) | 2.05494134 |
| 57 | Abnormal biliary tract physiology (HP:0012439) | 2.05494134 |
| 58 | Abnormality of DNA repair (HP:0003254) | 2.04235522 |
| 59 | Aplasia involving forearm bones (HP:0009822) | 2.01593118 |
| 60 | Absent forearm bone (HP:0003953) | 2.01593118 |
| 61 | Septo-optic dysplasia (HP:0100842) | 2.01027781 |
| 62 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.99854007 |
| 63 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.99854007 |
| 64 | Abnormality of the renal collecting system (HP:0004742) | 1.99714899 |
| 65 | Postaxial foot polydactyly (HP:0001830) | 1.98264324 |
| 66 | Absent radius (HP:0003974) | 1.98082704 |
| 67 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.97818687 |
| 68 | Broad metatarsal (HP:0001783) | 1.96296658 |
| 69 | Furrowed tongue (HP:0000221) | 1.95563255 |
| 70 | Medial flaring of the eyebrow (HP:0010747) | 1.93057022 |
| 71 | Type 2 muscle fiber atrophy (HP:0003554) | 1.91000792 |
| 72 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 1.89268472 |
| 73 | Lissencephaly (HP:0001339) | 1.89146946 |
| 74 | Ectopic kidney (HP:0000086) | 1.89107045 |
| 75 | Triphalangeal thumb (HP:0001199) | 1.88255383 |
| 76 | Preaxial foot polydactyly (HP:0001841) | 1.87056452 |
| 77 | Spastic tetraparesis (HP:0001285) | 1.86528735 |
| 78 | Tubulointerstitial abnormality (HP:0001969) | 1.86137464 |
| 79 | Abnormality of the labia minora (HP:0012880) | 1.85890461 |
| 80 | Dandy-Walker malformation (HP:0001305) | 1.85761255 |
| 81 | Sloping forehead (HP:0000340) | 1.85059974 |
| 82 | Tubulointerstitial fibrosis (HP:0005576) | 1.83306976 |
| 83 | Decreased central vision (HP:0007663) | 1.83270860 |
| 84 | Hyperalaninemia (HP:0003348) | 1.82781188 |
| 85 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.82781188 |
| 86 | Abnormality of alanine metabolism (HP:0010916) | 1.82781188 |
| 87 | Type I transferrin isoform profile (HP:0003642) | 1.81384742 |
| 88 | Supernumerary bones of the axial skeleton (HP:0009144) | 1.80895884 |
| 89 | Thyroid-stimulating hormone excess (HP:0002925) | 1.79648754 |
| 90 | Anophthalmia (HP:0000528) | 1.79417428 |
| 91 | Oligodactyly (HP:0012165) | 1.79176365 |
| 92 | Oligodactyly (hands) (HP:0001180) | 1.77478414 |
| 93 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 1.76973704 |
| 94 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.76843879 |
| 95 | Abnormal protein glycosylation (HP:0012346) | 1.76391685 |
| 96 | Abnormal glycosylation (HP:0012345) | 1.76391685 |
| 97 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.76391685 |
| 98 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.76391685 |
| 99 | Absent thumb (HP:0009777) | 1.76189914 |
| 100 | Chorioretinal atrophy (HP:0000533) | 1.76050879 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FRK | 8.43605481 |
| 2 | TXK | 3.56785088 |
| 3 | BCKDK | 3.26492282 |
| 4 | ADRBK2 | 2.98179205 |
| 5 | CDC7 | 2.95904158 |
| 6 | MST4 | 2.53048552 |
| 7 | ACVR1B | 2.48158505 |
| 8 | TAOK3 | 2.34637261 |
| 9 | ZAK | 2.23265011 |
| 10 | PIK3CA | 2.22204825 |
| 11 | NUAK1 | 2.14762408 |
| 12 | BMPR1B | 1.97733844 |
| 13 | TAF1 | 1.94817847 |
| 14 | PINK1 | 1.73305392 |
| 15 | ADRBK1 | 1.69491717 |
| 16 | MAP4K2 | 1.67676611 |
| 17 | GRK1 | 1.67527281 |
| 18 | PIK3CG | 1.60780858 |
| 19 | MKNK2 | 1.53002802 |
| 20 | TRIM28 | 1.50337125 |
| 21 | MAPKAPK3 | 1.32662312 |
| 22 | TEC | 1.23404631 |
| 23 | CDK3 | 1.18053550 |
| 24 | NME1 | 1.15341403 |
| 25 | WNK3 | 1.14415993 |
| 26 | PRKCG | 1.00177845 |
| 27 | WNK4 | 0.99984897 |
| 28 | DYRK2 | 0.97938887 |
| 29 | CHEK2 | 0.96404503 |
| 30 | BTK | 0.93710689 |
| 31 | MAP3K4 | 0.93326235 |
| 32 | DAPK2 | 0.93059081 |
| 33 | CHUK | 0.92461050 |
| 34 | IKBKB | 0.91299045 |
| 35 | FES | 0.91204711 |
| 36 | OXSR1 | 0.90371974 |
| 37 | MAPK13 | 0.87533374 |
| 38 | NTRK3 | 0.86900536 |
| 39 | MATK | 0.86636913 |
| 40 | VRK2 | 0.79784558 |
| 41 | CAMK1 | 0.77545522 |
| 42 | PRKCQ | 0.77149871 |
| 43 | TLK1 | 0.75871578 |
| 44 | IRAK4 | 0.74245170 |
| 45 | MKNK1 | 0.72399869 |
| 46 | NEK2 | 0.71692770 |
| 47 | ATR | 0.70288555 |
| 48 | MAP2K2 | 0.68835330 |
| 49 | PAK3 | 0.67169081 |
| 50 | STK38 | 0.66270254 |
| 51 | MAPKAPK5 | 0.62053463 |
| 52 | ITK | 0.61702050 |
| 53 | IRAK1 | 0.60319387 |
| 54 | RPS6KA5 | 0.60163555 |
| 55 | RPS6KA6 | 0.59679449 |
| 56 | PRKACA | 0.58416595 |
| 57 | NTRK2 | 0.57496222 |
| 58 | INSRR | 0.56275454 |
| 59 | TGFBR1 | 0.56187369 |
| 60 | STK39 | 0.55732211 |
| 61 | CAMK2A | 0.53288735 |
| 62 | CDK4 | 0.51834159 |
| 63 | PLK1 | 0.49187349 |
| 64 | CDK19 | 0.47405572 |
| 65 | AURKB | 0.42868741 |
| 66 | STK38L | 0.41814287 |
| 67 | OBSCN | 0.41742165 |
| 68 | PRKAA2 | 0.41367653 |
| 69 | MAP3K7 | 0.40282581 |
| 70 | PRKCA | 0.39482841 |
| 71 | PRKCZ | 0.39435695 |
| 72 | LYN | 0.38980636 |
| 73 | PRKACB | 0.38809874 |
| 74 | ERBB2 | 0.38629773 |
| 75 | MUSK | 0.38151707 |
| 76 | TRPM7 | 0.37847395 |
| 77 | MAPK3 | 0.37361827 |
| 78 | EPHA4 | 0.37206657 |
| 79 | GRK7 | 0.36708237 |
| 80 | STK11 | 0.36240423 |
| 81 | RPS6KB2 | 0.34882725 |
| 82 | BRD4 | 0.33828822 |
| 83 | CSNK1A1 | 0.33594850 |
| 84 | PRKACG | 0.33387143 |
| 85 | CHEK1 | 0.33281895 |
| 86 | PRKAA1 | 0.33281077 |
| 87 | MELK | 0.30317605 |
| 88 | DYRK3 | 0.29855647 |
| 89 | CSF1R | 0.29258381 |
| 90 | AURKA | 0.29214504 |
| 91 | ATM | 0.29176927 |
| 92 | AKT1 | 0.29153487 |
| 93 | DMPK | 0.29151982 |
| 94 | CSNK2A1 | 0.25984605 |
| 95 | CSNK1E | 0.25126474 |
| 96 | PIM1 | 0.24901766 |
| 97 | MAPK1 | 0.24608284 |
| 98 | PKN1 | 0.24560975 |
| 99 | KIT | 0.24405930 |
| 100 | PAK2 | 0.24316909 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Selenocompound metabolism_Homo sapiens_hsa00450 | 3.67183738 |
| 2 | Tryptophan metabolism_Homo sapiens_hsa00380 | 2.88864977 |
| 3 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 2.64839894 |
| 4 | Phototransduction_Homo sapiens_hsa04744 | 2.64119428 |
| 5 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.61457920 |
| 6 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.58781926 |
| 7 | Homologous recombination_Homo sapiens_hsa03440 | 2.18968997 |
| 8 | RNA polymerase_Homo sapiens_hsa03020 | 2.14257695 |
| 9 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 2.11246788 |
| 10 | Ribosome_Homo sapiens_hsa03010 | 2.07740620 |
| 11 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.84643201 |
| 12 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.82422952 |
| 13 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.81873656 |
| 14 | Sulfur relay system_Homo sapiens_hsa04122 | 1.80636882 |
| 15 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.79874102 |
| 16 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.78733980 |
| 17 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.78602272 |
| 18 | Nicotine addiction_Homo sapiens_hsa05033 | 1.71291468 |
| 19 | Olfactory transduction_Homo sapiens_hsa04740 | 1.69034488 |
| 20 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.65738370 |
| 21 | Base excision repair_Homo sapiens_hsa03410 | 1.61815059 |
| 22 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.59744905 |
| 23 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.57886793 |
| 24 | ABC transporters_Homo sapiens_hsa02010 | 1.50952509 |
| 25 | DNA replication_Homo sapiens_hsa03030 | 1.50169025 |
| 26 | Parkinsons disease_Homo sapiens_hsa05012 | 1.44419813 |
| 27 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.40582379 |
| 28 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.37842482 |
| 29 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.31117617 |
| 30 | Retinol metabolism_Homo sapiens_hsa00830 | 1.30581234 |
| 31 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.28489563 |
| 32 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.27813993 |
| 33 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.26055620 |
| 34 | Mismatch repair_Homo sapiens_hsa03430 | 1.23010200 |
| 35 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.21172875 |
| 36 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.20272726 |
| 37 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.19415029 |
| 38 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.18941292 |
| 39 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.18559837 |
| 40 | Huntingtons disease_Homo sapiens_hsa05016 | 1.18066715 |
| 41 | Histidine metabolism_Homo sapiens_hsa00340 | 1.17090712 |
| 42 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.12433882 |
| 43 | Alzheimers disease_Homo sapiens_hsa05010 | 1.11743170 |
| 44 | Morphine addiction_Homo sapiens_hsa05032 | 1.11612921 |
| 45 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.10040794 |
| 46 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 1.07145532 |
| 47 | Basal transcription factors_Homo sapiens_hsa03022 | 1.05269001 |
| 48 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.00801884 |
| 49 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.99535383 |
| 50 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.99081536 |
| 51 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.94684819 |
| 52 | Peroxisome_Homo sapiens_hsa04146 | 0.94102718 |
| 53 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.93824814 |
| 54 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.90474458 |
| 55 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.89866758 |
| 56 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.89430071 |
| 57 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.86297180 |
| 58 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.85607113 |
| 59 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.85332958 |
| 60 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.82013350 |
| 61 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.80618954 |
| 62 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.80302587 |
| 63 | Purine metabolism_Homo sapiens_hsa00230 | 0.80213497 |
| 64 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.79194191 |
| 65 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.78248064 |
| 66 | Circadian entrainment_Homo sapiens_hsa04713 | 0.75674503 |
| 67 | Asthma_Homo sapiens_hsa05310 | 0.74892747 |
| 68 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.71556975 |
| 69 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.69654565 |
| 70 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.69521431 |
| 71 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.67266113 |
| 72 | Taste transduction_Homo sapiens_hsa04742 | 0.64552961 |
| 73 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.64480323 |
| 74 | Lysine degradation_Homo sapiens_hsa00310 | 0.62429220 |
| 75 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.61314370 |
| 76 | Metabolic pathways_Homo sapiens_hsa01100 | 0.60981778 |
| 77 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.58638514 |
| 78 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.58188687 |
| 79 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.53985159 |
| 80 | Salivary secretion_Homo sapiens_hsa04970 | 0.52877611 |
| 81 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.51313548 |
| 82 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.50822722 |
| 83 | RNA degradation_Homo sapiens_hsa03018 | 0.50272830 |
| 84 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.49127415 |
| 85 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.47665059 |
| 86 | Protein export_Homo sapiens_hsa03060 | 0.46328521 |
| 87 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.46234653 |
| 88 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.45519328 |
| 89 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.41419491 |
| 90 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.41170029 |
| 91 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.40786533 |
| 92 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.38571840 |
| 93 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.38146673 |
| 94 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.37610301 |
| 95 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.35926673 |
| 96 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.33521582 |
| 97 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.32670698 |
| 98 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.30583915 |
| 99 | Renin secretion_Homo sapiens_hsa04924 | 0.30100724 |
| 100 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.28119305 |

