BRD7P1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)6.27299982
2behavioral response to nicotine (GO:0035095)5.58156246
3indolalkylamine metabolic process (GO:0006586)5.31886761
4indole-containing compound catabolic process (GO:0042436)5.13995301
5indolalkylamine catabolic process (GO:0046218)5.13995301
6tryptophan catabolic process (GO:0006569)5.13995301
7kynurenine metabolic process (GO:0070189)5.13319351
8regulation of posttranscriptional gene silencing (GO:0060147)4.85441493
9regulation of gene silencing by miRNA (GO:0060964)4.85441493
10regulation of gene silencing by RNA (GO:0060966)4.85441493
11L-fucose catabolic process (GO:0042355)4.34124269
12fucose catabolic process (GO:0019317)4.34124269
13L-fucose metabolic process (GO:0042354)4.34124269
14tryptophan metabolic process (GO:0006568)4.27114394
15indole-containing compound metabolic process (GO:0042430)4.02450087
16cellular biogenic amine catabolic process (GO:0042402)4.00809842
17amine catabolic process (GO:0009310)4.00809842
18epithelial cilium movement (GO:0003351)3.95756911
19mannosylation (GO:0097502)3.95066789
20nucleotide transmembrane transport (GO:1901679)3.93266599
21autophagic vacuole fusion (GO:0000046)3.93072590
22mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.80366510
23mitochondrial respiratory chain complex I assembly (GO:0032981)3.80366510
24NADH dehydrogenase complex assembly (GO:0010257)3.80366510
25regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.76613886
26regulation of mitotic spindle checkpoint (GO:1903504)3.76613886
27pyrimidine-containing compound transmembrane transport (GO:0072531)3.59140457
28rRNA catabolic process (GO:0016075)3.57393234
29signal peptide processing (GO:0006465)3.52857206
30protein complex biogenesis (GO:0070271)3.52820390
31respiratory chain complex IV assembly (GO:0008535)3.48364325
32pyrimidine dimer repair (GO:0006290)3.46918469
33kidney morphogenesis (GO:0060993)3.44239506
34establishment of protein localization to mitochondrial membrane (GO:0090151)3.31006605
35negative regulation of telomere maintenance (GO:0032205)3.26627093
36cell proliferation in forebrain (GO:0021846)3.23977830
37cilium movement (GO:0003341)3.22821283
38mitochondrial respiratory chain complex assembly (GO:0033108)3.19930171
39male meiosis I (GO:0007141)3.18025025
40serotonin metabolic process (GO:0042428)3.16370526
41behavioral response to ethanol (GO:0048149)3.13550766
42regulation of hippo signaling (GO:0035330)3.08226418
43cytochrome complex assembly (GO:0017004)3.04358605
44pyrimidine nucleobase catabolic process (GO:0006208)3.03663055
45cardiovascular system development (GO:0072358)3.01096730
46regulation of respiratory system process (GO:0044065)2.98816226
47detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.97742217
48appendage development (GO:0048736)2.90688649
49limb development (GO:0060173)2.90688649
50detection of light stimulus involved in visual perception (GO:0050908)2.90142157
51detection of light stimulus involved in sensory perception (GO:0050962)2.90142157
52primary amino compound metabolic process (GO:1901160)2.89163027
53axonemal dynein complex assembly (GO:0070286)2.88284553
54acrosome assembly (GO:0001675)2.86184660
55photoreceptor cell maintenance (GO:0045494)2.85874654
56cellular response to exogenous dsRNA (GO:0071360)2.82796746
57nonmotile primary cilium assembly (GO:0035058)2.82559313
58negative regulation of calcium ion transport into cytosol (GO:0010523)2.82423152
59ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162.78836670
60organelle membrane fusion (GO:0090174)2.78317965
61aromatic amino acid family catabolic process (GO:0009074)2.77681123
62regulation of hydrogen peroxide metabolic process (GO:0010310)2.77660040
63base-excision repair, AP site formation (GO:0006285)2.67248662
64L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.66080105
65negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948)2.65904909
66nucleobase catabolic process (GO:0046113)2.65457821
67recombinational repair (GO:0000725)2.64551140
68startle response (GO:0001964)2.64047396
69negative regulation of reactive oxygen species metabolic process (GO:2000378)2.63215446
70oxidative demethylation (GO:0070989)2.62859581
71amino acid salvage (GO:0043102)2.59782477
72L-methionine salvage (GO:0071267)2.59782477
73L-methionine biosynthetic process (GO:0071265)2.59782477
74positive regulation of Notch signaling pathway (GO:0045747)2.59411415
75forebrain neuron differentiation (GO:0021879)2.58487659
76somatic hypermutation of immunoglobulin genes (GO:0016446)2.58374240
77somatic diversification of immune receptors via somatic mutation (GO:0002566)2.58374240
78regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.58057056
79double-strand break repair via homologous recombination (GO:0000724)2.58046957
80regulation of short-term neuronal synaptic plasticity (GO:0048172)2.57750434
81regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.57209184
82benzene-containing compound metabolic process (GO:0042537)2.56636118
83protein K63-linked ubiquitination (GO:0070534)2.56117638
84peptidyl-histidine modification (GO:0018202)2.54332388
85ovulation cycle (GO:0042698)2.52740266
86positive regulation of defense response to virus by host (GO:0002230)2.52707087
87positive regulation of microtubule polymerization (GO:0031116)2.52593084
88phosphatidylinositol acyl-chain remodeling (GO:0036149)2.52191302
89aromatic amino acid family metabolic process (GO:0009072)2.50362273
90respiratory tube development (GO:0030323)2.49189560
91negative regulation of systemic arterial blood pressure (GO:0003085)2.48781859
92pseudouridine synthesis (GO:0001522)2.47476480
93chromatin remodeling at centromere (GO:0031055)2.47321922
94cellular biogenic amine biosynthetic process (GO:0042401)2.47267583
95lysosome localization (GO:0032418)2.46600054
96protein K6-linked ubiquitination (GO:0085020)2.45433354
97regulation of rhodopsin mediated signaling pathway (GO:0022400)2.43855467
98regulation of nuclear cell cycle DNA replication (GO:0033262)2.43830533
99NAD biosynthetic process (GO:0009435)2.43712932
100cell morphogenesis involved in neuron differentiation (GO:0048667)2.43523311

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.93679424
2VDR_22108803_ChIP-Seq_LS180_Human3.79912569
3ZNF274_21170338_ChIP-Seq_K562_Hela3.79454000
4RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.78892159
5IRF1_19129219_ChIP-ChIP_H3396_Human3.31879921
6IGF1R_20145208_ChIP-Seq_DFB_Human2.78311600
7TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.63695872
8GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.59916729
9TAF15_26573619_Chip-Seq_HEK293_Human2.26807944
10CTBP2_25329375_ChIP-Seq_LNCAP_Human1.94294154
11CTBP1_25329375_ChIP-Seq_LNCAP_Human1.91428989
12MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.91282685
13EWS_26573619_Chip-Seq_HEK293_Human1.91186557
14NOTCH1_21737748_ChIP-Seq_TLL_Human1.88243111
15ZFP57_27257070_Chip-Seq_ESCs_Mouse1.84454426
16GBX2_23144817_ChIP-Seq_PC3_Human1.80520825
17NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.75832490
18EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.72748324
19LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.72104273
20MYC_18940864_ChIP-ChIP_HL60_Human1.70647397
21HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.68543639
22TP63_19390658_ChIP-ChIP_HaCaT_Human1.66760608
23GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.66641593
24TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.59429774
25POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.59429774
26TP53_22573176_ChIP-Seq_HFKS_Human1.50770649
27GATA3_21878914_ChIP-Seq_MCF-7_Human1.48651385
28ER_23166858_ChIP-Seq_MCF-7_Human1.46683294
29MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.40524838
30ETV2_25802403_ChIP-Seq_MESCs_Mouse1.39548398
31REST_21632747_ChIP-Seq_MESCs_Mouse1.36103200
32RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.35732180
33ERA_21632823_ChIP-Seq_H3396_Human1.34078715
34GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.32757528
35NANOG_20526341_ChIP-Seq_ESCs_Human1.30746735
36TP53_16413492_ChIP-PET_HCT116_Human1.29665561
37BCAT_22108803_ChIP-Seq_LS180_Human1.28047894
38TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.26611607
39P300_19829295_ChIP-Seq_ESCs_Human1.25537191
40TAF2_19829295_ChIP-Seq_ESCs_Human1.24613867
41UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.24479350
42FOXA1_25329375_ChIP-Seq_VCAP_Human1.24111503
43FOXA1_27270436_Chip-Seq_PROSTATE_Human1.24111503
44AR_21572438_ChIP-Seq_LNCaP_Human1.21047250
45FUS_26573619_Chip-Seq_HEK293_Human1.20462353
46CBP_20019798_ChIP-Seq_JUKART_Human1.18682643
47IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.18682643
48NANOG_19829295_ChIP-Seq_ESCs_Human1.15823743
49SOX2_19829295_ChIP-Seq_ESCs_Human1.15823743
50E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.15571833
51STAT3_23295773_ChIP-Seq_U87_Human1.13495530
52PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.13063493
53FOXA1_21572438_ChIP-Seq_LNCaP_Human1.12707856
54HOXB7_26014856_ChIP-Seq_BT474_Human1.12090602
55AR_20517297_ChIP-Seq_VCAP_Human1.12089994
56EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.11653673
57AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.11440907
58SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.11304110
59NR3C1_21868756_ChIP-Seq_MCF10A_Human1.11027604
60OCT4_20526341_ChIP-Seq_ESCs_Human1.09821121
61GABP_17652178_ChIP-ChIP_JURKAT_Human1.08501237
62FLI1_27457419_Chip-Seq_LIVER_Mouse1.08171721
63NCOR_22424771_ChIP-Seq_293T_Human1.07616438
64STAT1_20625510_ChIP-Seq_HELA_Human1.06719078
65WDR5_24793694_ChIP-Seq_LNCAP_Human1.06625406
66VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.04934705
67P53_21459846_ChIP-Seq_SAOS-2_Human1.04441943
68CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.04057552
69PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.03080528
70RBPJ_21746931_ChIP-Seq_IB4_Human1.02857286
71POU3F2_20337985_ChIP-ChIP_501MEL_Human0.99690277
72NFE2_27457419_Chip-Seq_LIVER_Mouse0.98169271
73LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.97526712
74GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.97476113
75GATA3_26560356_Chip-Seq_TH1_Human0.96018482
76MYC_19829295_ChIP-Seq_ESCs_Human0.95066849
77STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.95056786
78ETS1_20019798_ChIP-Seq_JURKAT_Human0.93972902
79TCF4_23295773_ChIP-Seq_U87_Human0.93566115
80RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.93502254
81DROSHA_22980978_ChIP-Seq_HELA_Human0.92452585
82CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.92290486
83FOXH1_21741376_ChIP-Seq_ESCs_Human0.92132602
84FOXH1_21741376_ChIP-Seq_EPCs_Human0.91755791
85YY1_22570637_ChIP-Seq_MALME-3M_Human0.91187406
86PCGF2_27294783_Chip-Seq_NPCs_Mouse0.90994307
87ETV1_20927104_ChIP-Seq_GIST48_Human0.90665533
88SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.90533023
89JARID2_20064375_ChIP-Seq_MESCs_Mouse0.90486495
90CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.90484581
91AR_25329375_ChIP-Seq_VCAP_Human0.89272319
92JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.88797951
93TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88557830
94TCF4_22108803_ChIP-Seq_LS180_Human0.88117440
95CBX2_27304074_Chip-Seq_ESCs_Mouse0.87982789
96BMI1_23680149_ChIP-Seq_NPCS_Mouse0.87635116
97P300_27268052_Chip-Seq_Bcells_Human0.86256146
98RUNX2_22187159_ChIP-Seq_PCA_Human0.85599550
99STAT3_18555785_Chip-Seq_ESCs_Mouse0.85526410
100STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.85123694

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006292_abnormal_olfactory_placode4.45347196
2MP0003646_muscle_fatigue3.83961237
3MP0008057_abnormal_DNA_replication3.38465924
4MP0002736_abnormal_nociception_after2.65409719
5MP0002653_abnormal_ependyma_morphology2.45874972
6MP0001501_abnormal_sleep_pattern2.44294105
7MP0004147_increased_porphyrin_level2.35861148
8MP0004043_abnormal_pH_regulation2.29480531
9MP0001293_anophthalmia2.28449654
10MP0008877_abnormal_DNA_methylation2.26996578
11MP0004133_heterotaxia2.18182008
12MP0001968_abnormal_touch/_nociception2.16274826
13MP0002876_abnormal_thyroid_physiology2.01356455
14MP0004130_abnormal_muscle_cell1.99748125
15MP0002938_white_spotting1.91849252
16MP0000569_abnormal_digit_pigmentation1.90126977
17MP0006276_abnormal_autonomic_nervous1.86422197
18MP0005266_abnormal_metabolism1.85407143
19MP0005551_abnormal_eye_electrophysiolog1.82401274
20MP0004142_abnormal_muscle_tone1.79684385
21MP0000427_abnormal_hair_cycle1.74078932
22MP0001485_abnormal_pinna_reflex1.74037949
23MP0002638_abnormal_pupillary_reflex1.71235362
24MP0003195_calcinosis1.70818791
25MP0003136_yellow_coat_color1.70534089
26MP0009053_abnormal_anal_canal1.68975254
27MP0008961_abnormal_basal_metabolism1.67853750
28MP0006072_abnormal_retinal_apoptosis1.67138400
29MP0003693_abnormal_embryo_hatching1.63198978
30MP0008789_abnormal_olfactory_epithelium1.58472924
31MP0000631_abnormal_neuroendocrine_gland1.57884173
32MP0009046_muscle_twitch1.57234656
33MP0009745_abnormal_behavioral_response1.51946960
34MP0008872_abnormal_physiological_respon1.51016872
35MP0009379_abnormal_foot_pigmentation1.48772737
36MP0008995_early_reproductive_senescence1.47669577
37MP0003011_delayed_dark_adaptation1.47348454
38MP0004233_abnormal_muscle_weight1.41731548
39MP0004145_abnormal_muscle_electrophysio1.39161230
40MP0002272_abnormal_nervous_system1.33572064
41MP0003137_abnormal_impulse_conducting1.33347166
42MP0002735_abnormal_chemical_nociception1.29590402
43MP0003252_abnormal_bile_duct1.29289881
44MP0004742_abnormal_vestibular_system1.25776353
45MP0002009_preneoplasia1.25129748
46MP0005645_abnormal_hypothalamus_physiol1.17922343
47MP0002557_abnormal_social/conspecific_i1.16464681
48MP0003121_genomic_imprinting1.16089561
49MP0002572_abnormal_emotion/affect_behav1.15123650
50MP0001919_abnormal_reproductive_system1.13432570
51MP0005499_abnormal_olfactory_system1.12012599
52MP0005394_taste/olfaction_phenotype1.12012599
53MP0000566_synostosis1.02897850
54MP0002233_abnormal_nose_morphology1.02782384
55MP0002254_reproductive_system_inflammat1.01348446
56MP0002067_abnormal_sensory_capabilities1.00201002
57MP0005195_abnormal_posterior_eye0.99921792
58MP0002064_seizures0.97775347
59MP0002733_abnormal_thermal_nociception0.97329403
60MP0005253_abnormal_eye_physiology0.97316381
61MP0002277_abnormal_respiratory_mucosa0.97261159
62MP0003937_abnormal_limbs/digits/tail_de0.97052546
63MP0002184_abnormal_innervation0.96652404
64MP0003959_abnormal_lean_body0.92734008
65MP0005085_abnormal_gallbladder_physiolo0.92250722
66MP0002752_abnormal_somatic_nervous0.91413928
67MP0000647_abnormal_sebaceous_gland0.90660876
68MP0003890_abnormal_embryonic-extraembry0.90563755
69MP0001970_abnormal_pain_threshold0.88775475
70MP0005167_abnormal_blood-brain_barrier0.88450748
71MP0001486_abnormal_startle_reflex0.86749717
72MP0002332_abnormal_exercise_endurance0.84996431
73MP0005670_abnormal_white_adipose0.84838608
74MP0005391_vision/eye_phenotype0.83801833
75MP0006035_abnormal_mitochondrial_morpho0.83116592
76MP0003315_abnormal_perineum_morphology0.82361711
77MP0001986_abnormal_taste_sensitivity0.81839092
78MP0001873_stomach_inflammation0.81825717
79MP0000383_abnormal_hair_follicle0.79917066
80MP0002210_abnormal_sex_determination0.79170180
81MP0003718_maternal_effect0.78946623
82MP0000955_abnormal_spinal_cord0.78775351
83MP0000470_abnormal_stomach_morphology0.77730333
84MP0010329_abnormal_lipoprotein_level0.77374418
85MP0003638_abnormal_response/metabolism_0.77293496
86MP0003763_abnormal_thymus_physiology0.77282421
87MP0002160_abnormal_reproductive_system0.76757314
88MP0005389_reproductive_system_phenotype0.76692370
89MP0010030_abnormal_orbit_morphology0.76490662
90MP0004859_abnormal_synaptic_plasticity0.75744061
91MP0003698_abnormal_male_reproductive0.74754996
92MP0000372_irregular_coat_pigmentation0.74666153
93MP0005423_abnormal_somatic_nervous0.73346399
94MP0001348_abnormal_lacrimal_gland0.73319247
95MP0001270_distended_abdomen0.73038632
96MP0002089_abnormal_postnatal_growth/wei0.71947402
97MP0001905_abnormal_dopamine_level0.71909081
98MP0002063_abnormal_learning/memory/cond0.71855196
99MP0003635_abnormal_synaptic_transmissio0.71002369
100MP0001929_abnormal_gametogenesis0.70303903

Predicted human phenotypes

RankGene SetZ-score
1Pancreatic cysts (HP:0001737)4.79292787
2Pancreatic fibrosis (HP:0100732)4.78852344
3True hermaphroditism (HP:0010459)3.74095354
4Cystic liver disease (HP:0006706)3.45367133
5Tubular atrophy (HP:0000092)3.44632085
6Abolished electroretinogram (ERG) (HP:0000550)3.18669037
7Pendular nystagmus (HP:0012043)3.14792170
8Congenital stationary night blindness (HP:0007642)3.14288463
9Congenital, generalized hypertrichosis (HP:0004540)3.01653073
10Hypoplastic ischia (HP:0003175)3.00971019
11Rib fusion (HP:0000902)2.95919914
12Clumsiness (HP:0002312)2.88328508
13Hypoplasia of the pons (HP:0012110)2.85211518
14Sclerocornea (HP:0000647)2.82790096
15Nephronophthisis (HP:0000090)2.81205279
16Patellar aplasia (HP:0006443)2.79529836
17Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.76424865
18Inability to walk (HP:0002540)2.76112165
19Progressive inability to walk (HP:0002505)2.74693228
20Abnormality of the renal medulla (HP:0100957)2.65658313
21Chromosomal breakage induced by crosslinking agents (HP:0003221)2.64142426
22Protruding tongue (HP:0010808)2.62879664
23Abnormality of the pubic bones (HP:0003172)2.57944225
24Abnormality of the pons (HP:0007361)2.57561734
25Chronic hepatic failure (HP:0100626)2.57440317
26Molar tooth sign on MRI (HP:0002419)2.56644151
27Abnormality of midbrain morphology (HP:0002418)2.56644151
28Asplenia (HP:0001746)2.56610500
29Aplasia/Hypoplasia of the tibia (HP:0005772)2.56532724
30Aplasia/Hypoplasia of the patella (HP:0006498)2.56126722
31Type II lissencephaly (HP:0007260)2.55590369
32Large for gestational age (HP:0001520)2.45503413
33Decreased electroretinogram (ERG) amplitude (HP:0000654)2.45086209
34Reticulocytopenia (HP:0001896)2.42208997
35Aplasia/Hypoplasia of the spleen (HP:0010451)2.39227012
36Abnormality of the ischium (HP:0003174)2.38841943
37Chromsome breakage (HP:0040012)2.35700964
38Genetic anticipation (HP:0003743)2.32495102
39Prominent supraorbital ridges (HP:0000336)2.31432827
40Abnormality of the renal cortex (HP:0011035)2.30991773
41Anencephaly (HP:0002323)2.30029054
42Hyperglycinuria (HP:0003108)2.29373214
43Supernumerary spleens (HP:0009799)2.27418125
44Aplasia/Hypoplasia of the tongue (HP:0010295)2.24628631
45Abnormal number of erythroid precursors (HP:0012131)2.20986431
46Anterior segment dysgenesis (HP:0007700)2.20409981
47Hepatocellular necrosis (HP:0001404)2.18026632
48Abnormal ciliary motility (HP:0012262)2.17052706
49Congenital hepatic fibrosis (HP:0002612)2.15882272
50Renal dysplasia (HP:0000110)2.14807824
51Attenuation of retinal blood vessels (HP:0007843)2.14572877
52Hepatic necrosis (HP:0002605)2.12914304
53Cerebellar dysplasia (HP:0007033)2.11384129
54Abnormality of cells of the erythroid lineage (HP:0012130)2.11052371
55Duplicated collecting system (HP:0000081)2.08042040
56Bile duct proliferation (HP:0001408)2.05494134
57Abnormal biliary tract physiology (HP:0012439)2.05494134
58Abnormality of DNA repair (HP:0003254)2.04235522
59Aplasia involving forearm bones (HP:0009822)2.01593118
60Absent forearm bone (HP:0003953)2.01593118
61Septo-optic dysplasia (HP:0100842)2.01027781
62Abnormal respiratory motile cilium morphology (HP:0005938)1.99854007
63Abnormal respiratory epithelium morphology (HP:0012253)1.99854007
64Abnormality of the renal collecting system (HP:0004742)1.99714899
65Postaxial foot polydactyly (HP:0001830)1.98264324
66Absent radius (HP:0003974)1.98082704
67Aplasia/Hypoplasia of the uvula (HP:0010293)1.97818687
68Broad metatarsal (HP:0001783)1.96296658
69Furrowed tongue (HP:0000221)1.95563255
70Medial flaring of the eyebrow (HP:0010747)1.93057022
71Type 2 muscle fiber atrophy (HP:0003554)1.91000792
72Increased neuronal autofluorescent lipopigment (HP:0002074)1.89268472
73Lissencephaly (HP:0001339)1.89146946
74Ectopic kidney (HP:0000086)1.89107045
75Triphalangeal thumb (HP:0001199)1.88255383
76Preaxial foot polydactyly (HP:0001841)1.87056452
77Spastic tetraparesis (HP:0001285)1.86528735
78Tubulointerstitial abnormality (HP:0001969)1.86137464
79Abnormality of the labia minora (HP:0012880)1.85890461
80Dandy-Walker malformation (HP:0001305)1.85761255
81Sloping forehead (HP:0000340)1.85059974
82Tubulointerstitial fibrosis (HP:0005576)1.83306976
83Decreased central vision (HP:0007663)1.83270860
84Hyperalaninemia (HP:0003348)1.82781188
85Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.82781188
86Abnormality of alanine metabolism (HP:0010916)1.82781188
87Type I transferrin isoform profile (HP:0003642)1.81384742
88Supernumerary bones of the axial skeleton (HP:0009144)1.80895884
89Thyroid-stimulating hormone excess (HP:0002925)1.79648754
90Anophthalmia (HP:0000528)1.79417428
91Oligodactyly (HP:0012165)1.79176365
92Oligodactyly (hands) (HP:0001180)1.77478414
93Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.76973704
94Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.76843879
95Abnormal protein glycosylation (HP:0012346)1.76391685
96Abnormal glycosylation (HP:0012345)1.76391685
97Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.76391685
98Abnormal protein N-linked glycosylation (HP:0012347)1.76391685
99Absent thumb (HP:0009777)1.76189914
100Chorioretinal atrophy (HP:0000533)1.76050879

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK8.43605481
2TXK3.56785088
3BCKDK3.26492282
4ADRBK22.98179205
5CDC72.95904158
6MST42.53048552
7ACVR1B2.48158505
8TAOK32.34637261
9ZAK2.23265011
10PIK3CA2.22204825
11NUAK12.14762408
12BMPR1B1.97733844
13TAF11.94817847
14PINK11.73305392
15ADRBK11.69491717
16MAP4K21.67676611
17GRK11.67527281
18PIK3CG1.60780858
19MKNK21.53002802
20TRIM281.50337125
21MAPKAPK31.32662312
22TEC1.23404631
23CDK31.18053550
24NME11.15341403
25WNK31.14415993
26PRKCG1.00177845
27WNK40.99984897
28DYRK20.97938887
29CHEK20.96404503
30BTK0.93710689
31MAP3K40.93326235
32DAPK20.93059081
33CHUK0.92461050
34IKBKB0.91299045
35FES0.91204711
36OXSR10.90371974
37MAPK130.87533374
38NTRK30.86900536
39MATK0.86636913
40VRK20.79784558
41CAMK10.77545522
42PRKCQ0.77149871
43TLK10.75871578
44IRAK40.74245170
45MKNK10.72399869
46NEK20.71692770
47ATR0.70288555
48MAP2K20.68835330
49PAK30.67169081
50STK380.66270254
51MAPKAPK50.62053463
52ITK0.61702050
53IRAK10.60319387
54RPS6KA50.60163555
55RPS6KA60.59679449
56PRKACA0.58416595
57NTRK20.57496222
58INSRR0.56275454
59TGFBR10.56187369
60STK390.55732211
61CAMK2A0.53288735
62CDK40.51834159
63PLK10.49187349
64CDK190.47405572
65AURKB0.42868741
66STK38L0.41814287
67OBSCN0.41742165
68PRKAA20.41367653
69MAP3K70.40282581
70PRKCA0.39482841
71PRKCZ0.39435695
72LYN0.38980636
73PRKACB0.38809874
74ERBB20.38629773
75MUSK0.38151707
76TRPM70.37847395
77MAPK30.37361827
78EPHA40.37206657
79GRK70.36708237
80STK110.36240423
81RPS6KB20.34882725
82BRD40.33828822
83CSNK1A10.33594850
84PRKACG0.33387143
85CHEK10.33281895
86PRKAA10.33281077
87MELK0.30317605
88DYRK30.29855647
89CSF1R0.29258381
90AURKA0.29214504
91ATM0.29176927
92AKT10.29153487
93DMPK0.29151982
94CSNK2A10.25984605
95CSNK1E0.25126474
96PIM10.24901766
97MAPK10.24608284
98PKN10.24560975
99KIT0.24405930
100PAK20.24316909

Predicted pathways (KEGG)

RankGene SetZ-score
1Selenocompound metabolism_Homo sapiens_hsa004503.67183738
2Tryptophan metabolism_Homo sapiens_hsa003802.88864977
3Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.64839894
4Phototransduction_Homo sapiens_hsa047442.64119428
5alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.61457920
6Linoleic acid metabolism_Homo sapiens_hsa005912.58781926
7Homologous recombination_Homo sapiens_hsa034402.18968997
8RNA polymerase_Homo sapiens_hsa030202.14257695
9Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.11246788
10Ribosome_Homo sapiens_hsa030102.07740620
11Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.84643201
12Nitrogen metabolism_Homo sapiens_hsa009101.82422952
13Butanoate metabolism_Homo sapiens_hsa006501.81873656
14Sulfur relay system_Homo sapiens_hsa041221.80636882
15Fanconi anemia pathway_Homo sapiens_hsa034601.79874102
16Ether lipid metabolism_Homo sapiens_hsa005651.78733980
17Oxidative phosphorylation_Homo sapiens_hsa001901.78602272
18Nicotine addiction_Homo sapiens_hsa050331.71291468
19Olfactory transduction_Homo sapiens_hsa047401.69034488
20Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.65738370
21Base excision repair_Homo sapiens_hsa034101.61815059
22Fat digestion and absorption_Homo sapiens_hsa049751.59744905
23Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.57886793
24ABC transporters_Homo sapiens_hsa020101.50952509
25DNA replication_Homo sapiens_hsa030301.50169025
26Parkinsons disease_Homo sapiens_hsa050121.44419813
27beta-Alanine metabolism_Homo sapiens_hsa004101.40582379
28Non-homologous end-joining_Homo sapiens_hsa034501.37842482
29Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.31117617
30Retinol metabolism_Homo sapiens_hsa008301.30581234
31Glycerolipid metabolism_Homo sapiens_hsa005611.28489563
32Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.27813993
33Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.26055620
34Mismatch repair_Homo sapiens_hsa034301.23010200
35Pyrimidine metabolism_Homo sapiens_hsa002401.21172875
36Arachidonic acid metabolism_Homo sapiens_hsa005901.20272726
37Cardiac muscle contraction_Homo sapiens_hsa042601.19415029
38Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.18941292
39One carbon pool by folate_Homo sapiens_hsa006701.18559837
40Huntingtons disease_Homo sapiens_hsa050161.18066715
41Histidine metabolism_Homo sapiens_hsa003401.17090712
42Steroid hormone biosynthesis_Homo sapiens_hsa001401.12433882
43Alzheimers disease_Homo sapiens_hsa050101.11743170
44Morphine addiction_Homo sapiens_hsa050321.11612921
45Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.10040794
46Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.07145532
47Basal transcription factors_Homo sapiens_hsa030221.05269001
48Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.00801884
49Propanoate metabolism_Homo sapiens_hsa006400.99535383
50Caffeine metabolism_Homo sapiens_hsa002320.99081536
51Regulation of autophagy_Homo sapiens_hsa041400.94684819
52Peroxisome_Homo sapiens_hsa041460.94102718
53Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.93824814
54Cyanoamino acid metabolism_Homo sapiens_hsa004600.90474458
55Glutamatergic synapse_Homo sapiens_hsa047240.89866758
56Primary immunodeficiency_Homo sapiens_hsa053400.89430071
57Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.86297180
58Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.85607113
59Nucleotide excision repair_Homo sapiens_hsa034200.85332958
60Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.82013350
61Chemical carcinogenesis_Homo sapiens_hsa052040.80618954
62Ovarian steroidogenesis_Homo sapiens_hsa049130.80302587
63Purine metabolism_Homo sapiens_hsa002300.80213497
64Intestinal immune network for IgA production_Homo sapiens_hsa046720.79194191
65Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.78248064
66Circadian entrainment_Homo sapiens_hsa047130.75674503
67Asthma_Homo sapiens_hsa053100.74892747
68Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.71556975
69Calcium signaling pathway_Homo sapiens_hsa040200.69654565
70Fatty acid degradation_Homo sapiens_hsa000710.69521431
71Basal cell carcinoma_Homo sapiens_hsa052170.67266113
72Taste transduction_Homo sapiens_hsa047420.64552961
73Cysteine and methionine metabolism_Homo sapiens_hsa002700.64480323
74Lysine degradation_Homo sapiens_hsa003100.62429220
75Arginine and proline metabolism_Homo sapiens_hsa003300.61314370
76Metabolic pathways_Homo sapiens_hsa011000.60981778
77Pentose and glucuronate interconversions_Homo sapiens_hsa000400.58638514
78Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.58188687
79Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.53985159
80Salivary secretion_Homo sapiens_hsa049700.52877611
81Glycerophospholipid metabolism_Homo sapiens_hsa005640.51313548
82Graft-versus-host disease_Homo sapiens_hsa053320.50822722
83RNA degradation_Homo sapiens_hsa030180.50272830
84Serotonergic synapse_Homo sapiens_hsa047260.49127415
85Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.47665059
86Protein export_Homo sapiens_hsa030600.46328521
87Fatty acid elongation_Homo sapiens_hsa000620.46234653
88Maturity onset diabetes of the young_Homo sapiens_hsa049500.45519328
89Vitamin digestion and absorption_Homo sapiens_hsa049770.41419491
90Primary bile acid biosynthesis_Homo sapiens_hsa001200.41170029
91Fatty acid metabolism_Homo sapiens_hsa012120.40786533
92Vascular smooth muscle contraction_Homo sapiens_hsa042700.38571840
93Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.38146673
94Hedgehog signaling pathway_Homo sapiens_hsa043400.37610301
95Gastric acid secretion_Homo sapiens_hsa049710.35926673
96Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.33521582
97p53 signaling pathway_Homo sapiens_hsa041150.32670698
98cAMP signaling pathway_Homo sapiens_hsa040240.30583915
99Renin secretion_Homo sapiens_hsa049240.30100724
100SNARE interactions in vesicular transport_Homo sapiens_hsa041300.28119305

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