BRD8

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. This protein contains a bromodomain and is thought to be a nuclear receptor coactivator. Multiple alternatively spliced transcript variants that encode distinct isoforms have been identified. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synapsis (GO:0007129)5.82531428
2kinetochore organization (GO:0051383)4.66525572
3resolution of meiotic recombination intermediates (GO:0000712)4.39010145
4microtubule depolymerization (GO:0007019)4.37672431
5chromosome organization involved in meiosis (GO:0070192)4.32639498
6male meiosis I (GO:0007141)4.23784339
7kinetochore assembly (GO:0051382)4.20015201
8mitotic sister chromatid segregation (GO:0000070)4.14208277
9sister chromatid segregation (GO:0000819)4.07183881
10piRNA metabolic process (GO:0034587)4.04588361
11mitotic metaphase plate congression (GO:0007080)3.97817938
12CENP-A containing nucleosome assembly (GO:0034080)3.95737305
13chromatin remodeling at centromere (GO:0031055)3.89471815
14metaphase plate congression (GO:0051310)3.77133362
15male meiosis (GO:0007140)3.76177594
16DNA topological change (GO:0006265)3.71747181
17meiosis I (GO:0007127)3.62312946
18protein localization to kinetochore (GO:0034501)3.62309972
19meiotic chromosome segregation (GO:0045132)3.60848271
20telomere maintenance via semi-conservative replication (GO:0032201)3.60310212
21regulation of nuclear cell cycle DNA replication (GO:0033262)3.58279483
22reciprocal DNA recombination (GO:0035825)3.57335137
23reciprocal meiotic recombination (GO:0007131)3.57335137
24mitotic recombination (GO:0006312)3.55916580
25DNA replication-independent nucleosome assembly (GO:0006336)3.55567970
26DNA replication-independent nucleosome organization (GO:0034724)3.55567970
27telomere maintenance via recombination (GO:0000722)3.52835761
28regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.52412987
29establishment of chromosome localization (GO:0051303)3.51129928
30DNA double-strand break processing (GO:0000729)3.49286486
31histone exchange (GO:0043486)3.44649205
32nuclear pore complex assembly (GO:0051292)3.40974048
33protein localization to chromosome, centromeric region (GO:0071459)3.39429084
34nuclear pore organization (GO:0006999)3.34738010
35mitotic chromosome condensation (GO:0007076)3.33579247
36DNA strand elongation involved in DNA replication (GO:0006271)3.33360895
37DNA methylation involved in gamete generation (GO:0043046)3.33186891
38meiotic nuclear division (GO:0007126)3.28439311
39attachment of spindle microtubules to kinetochore (GO:0008608)3.27112243
40negative regulation of DNA-dependent DNA replication (GO:2000104)3.27024779
41protein K6-linked ubiquitination (GO:0085020)3.25849458
42DNA strand elongation (GO:0022616)3.25547524
43nucleotide-excision repair, DNA gap filling (GO:0006297)3.21366990
44DNA strand renaturation (GO:0000733)3.19476728
45meiotic cell cycle process (GO:1903046)3.18572199
46response to pheromone (GO:0019236)3.18112309
47DNA ligation (GO:0006266)3.17435590
48DNA replication initiation (GO:0006270)3.17104554
49spindle checkpoint (GO:0031577)3.12712716
50synaptonemal complex assembly (GO:0007130)3.10859751
51regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.09645822
52regulation of DNA endoreduplication (GO:0032875)3.08441155
53telomere maintenance via telomere lengthening (GO:0010833)3.08055441
54chromosome segregation (GO:0007059)3.04595852
55intra-S DNA damage checkpoint (GO:0031573)3.04544546
56nonmotile primary cilium assembly (GO:0035058)3.03540998
57somatic hypermutation of immunoglobulin genes (GO:0016446)3.01345744
58somatic diversification of immune receptors via somatic mutation (GO:0002566)3.01345744
59negative regulation of mitotic sister chromatid segregation (GO:0033048)3.00928987
60negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.00928987
61negative regulation of sister chromatid segregation (GO:0033046)3.00928987
62negative regulation of mitotic sister chromatid separation (GO:2000816)3.00928987
63regulation of mitotic spindle checkpoint (GO:1903504)3.00896688
64regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.00896688
65ATP-dependent chromatin remodeling (GO:0043044)3.00252864
66spindle assembly checkpoint (GO:0071173)2.99812915
67synaptonemal complex organization (GO:0070193)2.99364038
68regulation of meiosis I (GO:0060631)2.99299606
69negative regulation of chromosome segregation (GO:0051985)2.98697645
70regulation of chromosome segregation (GO:0051983)2.98286483
71regulation of sister chromatid segregation (GO:0033045)2.97901824
72regulation of mitotic sister chromatid separation (GO:0010965)2.97901824
73regulation of mitotic sister chromatid segregation (GO:0033047)2.97901824
74centriole replication (GO:0007099)2.97720180
75mitotic sister chromatid cohesion (GO:0007064)2.97672711
76regulation of mitotic metaphase/anaphase transition (GO:0030071)2.95948544
77DNA replication checkpoint (GO:0000076)2.94367916
78mismatch repair (GO:0006298)2.91179545
79negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.90772978
80mitotic spindle assembly checkpoint (GO:0007094)2.89780277
81mitotic spindle checkpoint (GO:0071174)2.89557159
82regulation of helicase activity (GO:0051095)2.89129989
83centriole assembly (GO:0098534)2.88752673
84regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.88213911
85negative regulation of DNA recombination (GO:0045910)2.87651941
86DNA unwinding involved in DNA replication (GO:0006268)2.86617981
87* histone H2A acetylation (GO:0043968)2.86070128
88cullin deneddylation (GO:0010388)2.83862107
89telomere maintenance (GO:0000723)2.83396849
90DNA synthesis involved in DNA repair (GO:0000731)2.82739680
91telomere organization (GO:0032200)2.81317072
92pore complex assembly (GO:0046931)2.80855438
93pyrimidine nucleobase catabolic process (GO:0006208)2.80541093
94regulation of histone H3-K9 methylation (GO:0051570)2.79556553
95DNA-dependent DNA replication (GO:0006261)2.77529620
96maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.77075834
97transcription-coupled nucleotide-excision repair (GO:0006283)2.73835625
98positive regulation of mitotic sister chromatid separation (GO:1901970)2.73702872
99positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.73702872
100positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.73702872
101sister chromatid cohesion (GO:0007062)2.73609533
102regulation of cilium movement (GO:0003352)2.71997811
103DNA geometric change (GO:0032392)2.71610374
104DNA replication-dependent nucleosome assembly (GO:0006335)2.70465196
105DNA replication-dependent nucleosome organization (GO:0034723)2.70465196
106DNA duplex unwinding (GO:0032508)2.69492325
107regulation of centriole replication (GO:0046599)2.69345332
108mitotic nuclear envelope disassembly (GO:0007077)2.68074686
109viral mRNA export from host cell nucleus (GO:0046784)2.67381711
110regulation of double-strand break repair via homologous recombination (GO:0010569)2.66727055
111DNA catabolic process, exonucleolytic (GO:0000738)2.66221666
112microtubule anchoring (GO:0034453)2.65053200
113regulation of timing of cell differentiation (GO:0048505)2.63901715
114postreplication repair (GO:0006301)2.63233628
115protein localization to chromosome (GO:0034502)2.62586307
116termination of RNA polymerase II transcription (GO:0006369)2.61172402
117DNA conformation change (GO:0071103)2.60693782
118regulation of spindle organization (GO:0090224)2.60247705
119intraciliary transport (GO:0042073)2.60219531
120spliceosomal complex assembly (GO:0000245)2.60102443
121replication fork processing (GO:0031297)2.59824530
122regulation of development, heterochronic (GO:0040034)2.59210483
123recombinational repair (GO:0000725)2.58719482
124translesion synthesis (GO:0019985)2.58297596
125mRNA export from nucleus (GO:0006406)2.57112538
126microtubule polymerization or depolymerization (GO:0031109)2.55571954
127double-strand break repair via nonhomologous end joining (GO:0006303)2.55293380
128non-recombinational repair (GO:0000726)2.55293380
129double-strand break repair via homologous recombination (GO:0000724)2.53755350
130regulation of centrosome cycle (GO:0046605)2.53651044
131protein deneddylation (GO:0000338)2.50887485
132DNA damage response, detection of DNA damage (GO:0042769)2.50719971
133epithelial cilium movement (GO:0003351)2.50090668
134regulation of sister chromatid cohesion (GO:0007063)2.47884179
135chromosome organization (GO:0051276)2.46046245

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.11560846
2FOXM1_23109430_ChIP-Seq_U2OS_Human5.07192369
3* E2F4_17652178_ChIP-ChIP_JURKAT_Human4.45059690
4* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.62006222
5ZNF274_21170338_ChIP-Seq_K562_Hela3.40574326
6* KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.04690732
7* MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.93452263
8MYC_18555785_ChIP-Seq_MESCs_Mouse2.81115920
9* EST1_17652178_ChIP-ChIP_JURKAT_Human2.75675125
10* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.60702546
11HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.60287645
12MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.56131530
13HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.53434086
14TP63_19390658_ChIP-ChIP_HaCaT_Human2.34043817
15IGF1R_20145208_ChIP-Seq_DFB_Human2.33625496
16SALL1_21062744_ChIP-ChIP_HESCs_Human2.33223903
17VDR_22108803_ChIP-Seq_LS180_Human2.29997618
18* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.28606175
19ELF1_17652178_ChIP-ChIP_JURKAT_Human2.27861089
20* GABP_17652178_ChIP-ChIP_JURKAT_Human2.25035910
21YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.17105729
22RBPJ_22232070_ChIP-Seq_NCS_Mouse2.15367946
23* CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.15190330
24* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.14836289
25MYC_19079543_ChIP-ChIP_MESCs_Mouse2.12153405
26ELK1_19687146_ChIP-ChIP_HELA_Human2.04399657
27* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.04202455
28VDR_23849224_ChIP-Seq_CD4+_Human2.01884819
29HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.98037243
30E2F1_21310950_ChIP-Seq_MCF-7_Human1.96220937
31GBX2_23144817_ChIP-Seq_PC3_Human1.92229786
32ETS1_20019798_ChIP-Seq_JURKAT_Human1.91827669
33CIITA_25753668_ChIP-Seq_RAJI_Human1.87841315
34FOXP3_21729870_ChIP-Seq_TREG_Human1.87356519
35* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.85983556
36CREB1_15753290_ChIP-ChIP_HEK293T_Human1.85736103
37PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.77304060
38* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.74494618
39TAF15_26573619_Chip-Seq_HEK293_Human1.73721138
40EGR1_19374776_ChIP-ChIP_THP-1_Human1.71762059
41THAP11_20581084_ChIP-Seq_MESCs_Mouse1.70507238
42ZFP57_27257070_Chip-Seq_ESCs_Mouse1.68894871
43CTBP2_25329375_ChIP-Seq_LNCAP_Human1.68410579
44FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.66549087
45SOX2_18555785_ChIP-Seq_MESCs_Mouse1.64259936
46NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.63749096
47TTF2_22483619_ChIP-Seq_HELA_Human1.61516756
48* XRN2_22483619_ChIP-Seq_HELA_Human1.60693532
49* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.55725406
50* PADI4_21655091_ChIP-ChIP_MCF-7_Human1.54108243
51CTBP1_25329375_ChIP-Seq_LNCAP_Human1.52789904
52HOXB4_20404135_ChIP-ChIP_EML_Mouse1.51133625
53EZH2_22144423_ChIP-Seq_EOC_Human1.48560091
54DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.47535355
55* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.46521935
56P300_19829295_ChIP-Seq_ESCs_Human1.45876707
57AR_21909140_ChIP-Seq_LNCAP_Human1.45742242
58CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.42215776
59ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.42127659
60CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.40934810
61NANOG_18555785_ChIP-Seq_MESCs_Mouse1.39902316
62POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.39287069
63E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.37890304
64POU5F1_16153702_ChIP-ChIP_HESCs_Human1.37734663
65RNF2_27304074_Chip-Seq_NSC_Mouse1.36069416
66EWS_26573619_Chip-Seq_HEK293_Human1.31384461
67DCP1A_22483619_ChIP-Seq_HELA_Human1.30857316
68E2F1_18555785_ChIP-Seq_MESCs_Mouse1.30476842
69POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.30180114
70CBX2_27304074_Chip-Seq_ESCs_Mouse1.28720545
71GABP_19822575_ChIP-Seq_HepG2_Human1.27423274
72SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.26605870
73FUS_26573619_Chip-Seq_HEK293_Human1.21431120
74TP53_22573176_ChIP-Seq_HFKS_Human1.20076744
75MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.20002452
76YY1_21170310_ChIP-Seq_MESCs_Mouse1.19239236
77* NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.17247186
78MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.16156962
79SRF_21415370_ChIP-Seq_HL-1_Mouse1.15286280
80ER_23166858_ChIP-Seq_MCF-7_Human1.14496349
81KDM5A_27292631_Chip-Seq_BREAST_Human1.14431701
82FLI1_27457419_Chip-Seq_LIVER_Mouse1.13348313
83GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13150148
84SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.12987582
85ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.11290890
86RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.10692465
87CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.10618323
88AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.09960712
89SOX2_16153702_ChIP-ChIP_HESCs_Human1.09949658
90BCAT_22108803_ChIP-Seq_LS180_Human1.08493084
91GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.07716831
92HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.07542540
93BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.07509149
94EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.07460647
95SMAD4_21799915_ChIP-Seq_A2780_Human1.05951857
96UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.04828109
97KLF5_20875108_ChIP-Seq_MESCs_Mouse1.04819138
98ERG_20887958_ChIP-Seq_HPC-7_Mouse1.01360185
99PIAS1_25552417_ChIP-Seq_VCAP_Human1.00653542
100PCGF2_27294783_Chip-Seq_ESCs_Mouse1.00146083
101TCF4_23295773_ChIP-Seq_U87_Human0.99685737
102STAT3_23295773_ChIP-Seq_U87_Human0.99487116
103MYC_18940864_ChIP-ChIP_HL60_Human0.99024727
104ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.98630754
105IRF1_19129219_ChIP-ChIP_H3396_Human0.97730395
106EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.96788201
107SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.94933335
108SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.94724043
109* CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.93806499
110AR_25329375_ChIP-Seq_VCAP_Human0.93618234
111* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.93498050
112TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.93317606
113SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.92989719
114TOP2B_26459242_ChIP-Seq_MCF-7_Human0.92784127
115KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.92660983
116SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.91861086
117CBP_20019798_ChIP-Seq_JUKART_Human0.91683123
118IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.91683123
119NOTCH1_21737748_ChIP-Seq_TLL_Human0.91605797
120TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.91354353
121TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.90908076
122GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.90606729
123SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.87991513
124NANOG_16153702_ChIP-ChIP_HESCs_Human0.87938017
125RUNX2_22187159_ChIP-Seq_PCA_Human0.87844969
126E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.86587914
127SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.86586906
128PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.86384830
129POU3F2_20337985_ChIP-ChIP_501MEL_Human0.86348351
130FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.84118425
131NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.84057356
132NANOG_21062744_ChIP-ChIP_HESCs_Human0.80240770
133SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.79764299
134* ZFX_18555785_ChIP-Seq_MESCs_Mouse0.79345186
135GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.78926514
136FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.78483476
137KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.77870857
138KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.77870857
139KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.77870857
140PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.77518519
141SOX9_26525672_Chip-Seq_HEART_Mouse0.77357891
142CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.73604962

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability3.80148045
2MP0008057_abnormal_DNA_replication3.76804613
3MP0003693_abnormal_embryo_hatching3.57045522
4MP0003111_abnormal_nucleus_morphology3.45243422
5MP0008058_abnormal_DNA_repair3.24076875
6MP0003077_abnormal_cell_cycle2.99390520
7MP0006292_abnormal_olfactory_placode2.98975699
8MP0008877_abnormal_DNA_methylation2.84192530
9MP0008007_abnormal_cellular_replicative2.51105401
10MP0004957_abnormal_blastocyst_morpholog2.50343898
11MP0003787_abnormal_imprinting2.43037305
12MP0001188_hyperpigmentation2.41662293
13MP0003121_genomic_imprinting2.32519933
14MP0003880_abnormal_central_pattern2.18639968
15MP0008932_abnormal_embryonic_tissue2.07594057
16MP0001986_abnormal_taste_sensitivity1.92273595
17MP0001529_abnormal_vocalization1.91339010
18MP0001984_abnormal_olfaction1.85600822
19MP0003786_premature_aging1.83626352
20MP0003890_abnormal_embryonic-extraembry1.80812229
21MP0008789_abnormal_olfactory_epithelium1.74337224
22MP0002938_white_spotting1.72318084
23MP0003123_paternal_imprinting1.65523278
24MP0004147_increased_porphyrin_level1.60966966
25MP0000015_abnormal_ear_pigmentation1.58348568
26MP0005174_abnormal_tail_pigmentation1.58046903
27MP0000372_irregular_coat_pigmentation1.55424236
28MP0005409_darkened_coat_color1.50878846
29MP0003136_yellow_coat_color1.50701519
30MP0002009_preneoplasia1.50099291
31MP0005394_taste/olfaction_phenotype1.49274867
32MP0005499_abnormal_olfactory_system1.49274867
33MP0000566_synostosis1.48665689
34MP0002160_abnormal_reproductive_system1.45048573
35MP0003718_maternal_effect1.43334616
36MP0003122_maternal_imprinting1.43282359
37MP0002210_abnormal_sex_determination1.40834774
38MP0005551_abnormal_eye_electrophysiolog1.39653458
39MP0003941_abnormal_skin_development1.39070339
40MP0000350_abnormal_cell_proliferation1.38112130
41MP0000778_abnormal_nervous_system1.37576869
42MP0000647_abnormal_sebaceous_gland1.37267248
43MP0002751_abnormal_autonomic_nervous1.34704749
44MP0004133_heterotaxia1.34455029
45MP0005187_abnormal_penis_morphology1.33886346
46MP0005646_abnormal_pituitary_gland1.33423355
47MP0003315_abnormal_perineum_morphology1.31563076
48MP0001486_abnormal_startle_reflex1.31336989
49MP0002396_abnormal_hematopoietic_system1.28084006
50MP0002095_abnormal_skin_pigmentation1.27764570
51MP0005389_reproductive_system_phenotype1.25320932
52MP0000049_abnormal_middle_ear1.25012622
53MP0010307_abnormal_tumor_latency1.21004247
54MP0004808_abnormal_hematopoietic_stem1.20285219
55MP0001929_abnormal_gametogenesis1.19409459
56MP0009697_abnormal_copulation1.19364612
57MP0000678_abnormal_parathyroid_gland1.18784752
58MP0002736_abnormal_nociception_after1.18133562
59MP0006072_abnormal_retinal_apoptosis1.18110817
60MP0001919_abnormal_reproductive_system1.17849449
61MP0002653_abnormal_ependyma_morphology1.16090069
62MP0002102_abnormal_ear_morphology1.14840030
63MP0002085_abnormal_embryonic_tissue1.13764655
64MP0001672_abnormal_embryogenesis/_devel1.12008876
65MP0005380_embryogenesis_phenotype1.12008876
66MP0000427_abnormal_hair_cycle1.11315820
67MP0001293_anophthalmia1.11143002
68MP0009046_muscle_twitch1.09856062
69MP0001145_abnormal_male_reproductive1.07801331
70MP0001968_abnormal_touch/_nociception1.07225669
71MP0002163_abnormal_gland_morphology1.07215821
72MP0002234_abnormal_pharynx_morphology1.05123045
73MP0000383_abnormal_hair_follicle1.05094886
74MP0000631_abnormal_neuroendocrine_gland1.05054387
75MP0001286_abnormal_eye_development1.04788402
76MP0003937_abnormal_limbs/digits/tail_de1.04663702
77MP0001485_abnormal_pinna_reflex1.03255709
78MP0001299_abnormal_eye_distance/1.03170570
79MP0002638_abnormal_pupillary_reflex1.01199817
80MP0001697_abnormal_embryo_size1.00894589
81MP0002557_abnormal_social/conspecific_i1.00543516
82MP0009745_abnormal_behavioral_response0.99577301
83MP0005367_renal/urinary_system_phenotyp0.98791491
84MP0000516_abnormal_urinary_system0.98791491
85MP0002084_abnormal_developmental_patter0.98582205
86MP0010030_abnormal_orbit_morphology0.98223425
87MP0006276_abnormal_autonomic_nervous0.98091331
88MP0001346_abnormal_lacrimal_gland0.97429690
89MP0000313_abnormal_cell_death0.97274953
90MP0001730_embryonic_growth_arrest0.97247981
91MP0000653_abnormal_sex_gland0.97224354
92MP0004885_abnormal_endolymph0.96435975
93MP0005645_abnormal_hypothalamus_physiol0.94951316
94MP0003698_abnormal_male_reproductive0.93824509
95MP0002272_abnormal_nervous_system0.93481609
96MP0000703_abnormal_thymus_morphology0.92769113
97MP0003763_abnormal_thymus_physiology0.92434913
98MP0009379_abnormal_foot_pigmentation0.92115706
99MP0003984_embryonic_growth_retardation0.91505597
100MP0001119_abnormal_female_reproductive0.90925758
101MP0001186_pigmentation_phenotype0.90782633
102MP0008995_early_reproductive_senescence0.89983529
103MP0005253_abnormal_eye_physiology0.89891972
104MP0002184_abnormal_innervation0.89747561
105MP0002088_abnormal_embryonic_growth/wei0.89210164
106MP0002080_prenatal_lethality0.88054739
107MP0003755_abnormal_palate_morphology0.85453760
108MP0003938_abnormal_ear_development0.85301800
109MP0000490_abnormal_crypts_of0.84934296
110MP0002152_abnormal_brain_morphology0.84788670
111MP0002277_abnormal_respiratory_mucosa0.83992383
112MP0000569_abnormal_digit_pigmentation0.83595603
113MP0002161_abnormal_fertility/fecundity0.83027698
114MP0005075_abnormal_melanosome_morpholog0.82933648
115MP0004197_abnormal_fetal_growth/weight/0.82778612
116MP0002075_abnormal_coat/hair_pigmentati0.82765318
117MP0000955_abnormal_spinal_cord0.82695091
118MP0002249_abnormal_larynx_morphology0.82643151
119MP0003935_abnormal_craniofacial_develop0.82360566
120MP0002282_abnormal_trachea_morphology0.81996361
121MP0003861_abnormal_nervous_system0.80532558
122MP0001764_abnormal_homeostasis0.78534507
123MP0002116_abnormal_craniofacial_bone0.77574268
124MP0003567_abnormal_fetal_cardiomyocyte0.77052102
125MP0000432_abnormal_head_morphology0.77032860
126MP0002233_abnormal_nose_morphology0.76669202
127MP0006035_abnormal_mitochondrial_morpho0.76269790
128MP0002752_abnormal_somatic_nervous0.76141402
129MP0002177_abnormal_outer_ear0.74712625
130MP0002064_seizures0.74626075
131MP0003119_abnormal_digestive_system0.73982904
132MP0002019_abnormal_tumor_incidence0.73586415
133MP0005391_vision/eye_phenotype0.73563295
134MP0002067_abnormal_sensory_capabilities0.72549065
135MP0000026_abnormal_inner_ear0.72546421
136MP0005171_absent_coat_pigmentation0.72261250
137MP0002086_abnormal_extraembryonic_tissu0.71697668
138MP0004742_abnormal_vestibular_system0.71336446
139MP0001324_abnormal_eye_pigmentation0.71031402
140MP0009703_decreased_birth_body0.68149685
141MP0003943_abnormal_hepatobiliary_system0.67309982

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)4.13181512
2Chromsome breakage (HP:0040012)4.05275809
3Meckel diverticulum (HP:0002245)3.08736735
4Oligodactyly (hands) (HP:0001180)3.05636792
5Supernumerary spleens (HP:0009799)3.04544026
6Abnormality of the ileum (HP:0001549)2.96570918
7Aplasia/Hypoplasia of the uvula (HP:0010293)2.93564522
8Abnormality of chromosome stability (HP:0003220)2.92375743
9Abnormality of the preputium (HP:0100587)2.80271661
10Nephroblastoma (Wilms tumor) (HP:0002667)2.78375218
11Ectopic kidney (HP:0000086)2.72224682
12Birth length less than 3rd percentile (HP:0003561)2.70613777
13True hermaphroditism (HP:0010459)2.69717739
14Patellar aplasia (HP:0006443)2.67006923
15Volvulus (HP:0002580)2.66104693
16Embryonal renal neoplasm (HP:0011794)2.65072657
17Medulloblastoma (HP:0002885)2.61632338
1811 pairs of ribs (HP:0000878)2.60318726
19Abnormality of the renal collecting system (HP:0004742)2.59892681
20Duplicated collecting system (HP:0000081)2.59090333
21Ependymoma (HP:0002888)2.58005527
22Pancreatic fibrosis (HP:0100732)2.55844044
23Abnormal lung lobation (HP:0002101)2.54222017
24Intestinal atresia (HP:0011100)2.53993812
25Oligodactyly (HP:0012165)2.52615769
26Aplasia/Hypoplasia of the patella (HP:0006498)2.49167345
27Small intestinal stenosis (HP:0012848)2.48449317
28Duodenal stenosis (HP:0100867)2.48449317
29Myelodysplasia (HP:0002863)2.42647003
30Astrocytoma (HP:0009592)2.42345621
31Abnormality of the astrocytes (HP:0100707)2.42345621
32Abnormality of the labia minora (HP:0012880)2.35294121
33Sloping forehead (HP:0000340)2.31579098
34Pancreatic cysts (HP:0001737)2.30948847
35Genital tract atresia (HP:0001827)2.27659451
36Reticulocytopenia (HP:0001896)2.25254599
37Vaginal atresia (HP:0000148)2.23105694
38Abnormality of the carotid arteries (HP:0005344)2.21371776
39Colon cancer (HP:0003003)2.16894417
40Clubbing of toes (HP:0100760)2.15250665
41Preaxial hand polydactyly (HP:0001177)2.14831140
42Impulsivity (HP:0100710)2.14457284
43Gonadotropin excess (HP:0000837)2.14133904
44Abnormality of the duodenum (HP:0002246)2.14011733
45Deep philtrum (HP:0002002)2.12201845
46Abnormal number of incisors (HP:0011064)2.08581894
47Absent radius (HP:0003974)2.08503032
48Medial flaring of the eyebrow (HP:0010747)2.06712042
49Bone marrow hypocellularity (HP:0005528)2.06675913
50Molar tooth sign on MRI (HP:0002419)2.05256636
51Abnormality of midbrain morphology (HP:0002418)2.05256636
52Increased nuchal translucency (HP:0010880)2.04892890
53Nephrogenic diabetes insipidus (HP:0009806)2.03126275
54Congenital primary aphakia (HP:0007707)2.02253547
55Nephronophthisis (HP:0000090)2.00371930
56Optic nerve coloboma (HP:0000588)1.99303019
57Acute necrotizing encephalopathy (HP:0006965)1.99211737
58Postaxial hand polydactyly (HP:0001162)1.98709827
59Acute lymphatic leukemia (HP:0006721)1.97721539
60Aplasia involving forearm bones (HP:0009822)1.94900097
61Absent forearm bone (HP:0003953)1.94900097
62Cortical dysplasia (HP:0002539)1.91447239
63Multicystic kidney dysplasia (HP:0000003)1.90998821
64Abnormality of the renal cortex (HP:0011035)1.90969460
65Gait imbalance (HP:0002141)1.90852096
66Aplasia/Hypoplasia of the sternum (HP:0006714)1.90709861
67Anencephaly (HP:0002323)1.89996403
68Breast hypoplasia (HP:0003187)1.89326099
69Abnormal hair whorl (HP:0010721)1.88814009
70Anal stenosis (HP:0002025)1.87774734
71Postaxial foot polydactyly (HP:0001830)1.86918641
72Triphalangeal thumb (HP:0001199)1.85261191
73Absent thumb (HP:0009777)1.85086984
74Sclerocornea (HP:0000647)1.84050897
75Dandy-Walker malformation (HP:0001305)1.83646615
76Increased CSF lactate (HP:0002490)1.83023848
77Short thumb (HP:0009778)1.82683933
78Abnormality of DNA repair (HP:0003254)1.82649600
79Aqueductal stenosis (HP:0002410)1.80132857
80Chronic hepatic failure (HP:0100626)1.78700016
81Prominent nasal bridge (HP:0000426)1.78197157
82Acute encephalopathy (HP:0006846)1.77401322
83Retinal dysplasia (HP:0007973)1.77189457
84Tubulointerstitial nephritis (HP:0001970)1.76474402
85Abnormal biliary tract physiology (HP:0012439)1.75799345
86Bile duct proliferation (HP:0001408)1.75799345
87Neoplasm of striated muscle (HP:0009728)1.75712854
88Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.75089107
89Broad distal phalanx of finger (HP:0009836)1.74859124
90Median cleft lip (HP:0000161)1.74605092
91Holoprosencephaly (HP:0001360)1.74562360
92Decreased testicular size (HP:0008734)1.73945246
93Specific learning disability (HP:0001328)1.73576549
94Poor coordination (HP:0002370)1.73029520
95Occipital encephalocele (HP:0002085)1.72859656
96Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.72659608
97Short 4th metacarpal (HP:0010044)1.72659608
98Abdominal situs inversus (HP:0003363)1.71698421
99Abnormality of abdominal situs (HP:0011620)1.71698421
100Esophageal atresia (HP:0002032)1.70846101
101Premature graying of hair (HP:0002216)1.70642239
102Rhabdomyosarcoma (HP:0002859)1.70584080
103Type II lissencephaly (HP:0007260)1.70490572
104Abnormal mitochondria in muscle tissue (HP:0008316)1.69744101
105Facial cleft (HP:0002006)1.69539132
106Type I transferrin isoform profile (HP:0003642)1.69026653
107Dynein arm defect of respiratory motile cilia (HP:0012255)1.68920794
108Absent/shortened dynein arms (HP:0200106)1.68920794
109Progressive inability to walk (HP:0002505)1.68614347
110Abnormality of the fingertips (HP:0001211)1.68301404
111Hypoplasia of the capital femoral epiphysis (HP:0003090)1.68013450
112Pendular nystagmus (HP:0012043)1.67848615
113Aganglionic megacolon (HP:0002251)1.67670367
114Renal hypoplasia (HP:0000089)1.66749902
115Neoplasm of the colon (HP:0100273)1.66665675
116Methylmalonic acidemia (HP:0002912)1.66550829
117Progressive macrocephaly (HP:0004481)1.66533570
118Aplasia/Hypoplasia of the tongue (HP:0010295)1.65205708
119Abnormality of the renal medulla (HP:0100957)1.64978789
120Abnormality of chromosome segregation (HP:0002916)1.64523555
121Gastrointestinal atresia (HP:0002589)1.64245539
122Abnormal respiratory epithelium morphology (HP:0012253)1.63952711
123Abnormal respiratory motile cilium morphology (HP:0005938)1.63952711
124Papillary thyroid carcinoma (HP:0002895)1.63623870
125Neoplasm of the adrenal cortex (HP:0100641)1.63212763
126Cerebellar dysplasia (HP:0007033)1.63047147
127Embryonal neoplasm (HP:0002898)1.62717702
128Congenital hepatic fibrosis (HP:0002612)1.62592928
129Tracheoesophageal fistula (HP:0002575)1.62567802
130Mitochondrial inheritance (HP:0001427)1.61889909
131Glioma (HP:0009733)1.60940838
132Abnormality of the incisor (HP:0000676)1.60880280
133Horseshoe kidney (HP:0000085)1.60631384
134Optic nerve hypoplasia (HP:0000609)1.60455668
135Degeneration of anterior horn cells (HP:0002398)1.60100832
136Abnormality of the anterior horn cell (HP:0006802)1.60100832
137Agnosia (HP:0010524)1.60018034
138Lip pit (HP:0100267)1.59519860
139Long clavicles (HP:0000890)1.59196153
140Oculomotor apraxia (HP:0000657)1.58736334
141Cystic liver disease (HP:0006706)1.57249016
142Astigmatism (HP:0000483)1.56651898
143Aplastic anemia (HP:0001915)1.56519920
144Severe visual impairment (HP:0001141)1.55724162

Predicted kinase interactions (KEA)

RankGene SetZ-score
1SRPK13.94897837
2BUB13.55316813
3PNCK3.33421593
4CDC73.11408539
5MKNK22.89092715
6AKT32.81399004
7MKNK12.71582357
8MAP4K22.62438815
9ZAK2.56958759
10WEE12.55592696
11PLK42.54181379
12PASK2.29422574
13STK162.11707474
14CCNB12.11175428
15CASK2.05579081
16PLK32.04956316
17VRK12.00238171
18TTK1.96283322
19ATR1.87358035
20TSSK61.87203421
21BRSK21.81034427
22YES11.79494837
23NEK21.78965594
24PLK11.77512069
25BRD41.76680415
26CDK121.65393153
27BCR1.64738417
28CHEK21.64632907
29TRIM281.60747177
30VRK21.59105025
31FRK1.56525979
32MAP3K41.55228885
33ERBB31.50723760
34AURKB1.49251213
35TLK11.42156670
36MARK11.42025874
37NUAK11.40261499
38ACVR1B1.36122573
39EPHA41.28091363
40CDK71.26760670
41CHEK11.22660219
42CDK31.17848966
43PBK1.17215100
44STK41.16255557
45SGK21.15776096
46EIF2AK21.13994581
47ATM1.12358082
48BRSK11.11523202
49STK38L1.09598278
50CLK11.09246422
51DYRK31.08150919
52PRPF4B1.07609607
53PINK11.06721162
54RPS6KB21.02878425
55EIF2AK31.00198212
56PDK20.99482841
57MAPK130.98470836
58IRAK40.97389907
59AURKA0.94495919
60CSNK1G10.94232038
61TXK0.90962080
62BMPR1B0.90211306
63IRAK30.87216378
64MINK10.85496091
65EPHA20.84187780
66CDK40.81058622
67MAP2K70.80482870
68OXSR10.79852378
69CDK20.79745326
70CDK10.79201758
71TEC0.78310397
72IRAK10.77560782
73CDK190.77135854
74WNK40.75104726
75CDK80.75012005
76PLK20.74825711
77PAK30.74578593
78NEK60.74422681
79CAMK1G0.72774203
80CSNK1G20.72224782
81MELK0.72213978
82CSNK1G30.70661451
83BRAF0.70506221
84SIK30.68817448
85PRKCG0.67164937
86MARK30.66019208
87PRKCI0.64919659
88PKN10.63413498
89TAF10.62236932
90NTRK30.61492459
91ADRBK20.61171888
92NEK10.60858834
93BMPR20.60507211
94IRAK20.60048055
95UHMK10.60018028
96STK240.59577277
97TGFBR10.58994415
98FGFR20.58718364
99STK30.58048317
100GRK10.57185078
101CSNK2A10.56407737
102CSNK1A1L0.56293169
103MET0.55083172
104MST40.52844798
105PRKCE0.51560926
106RPS6KA50.51545730
107RPS6KB10.50605324
108CSNK2A20.50298492
109EIF2AK10.49729270
110STK390.49556212
111CSNK1E0.49090808
112PRKDC0.48684299
113RPS6KA40.47658563
114FER0.47054420
115NME10.46285375
116PIM10.46281249
117NLK0.46087713
118SGK30.46084047
119MAPK140.44282608
120BCKDK0.41937107
121FGFR10.40734888
122KSR10.40682826
123PTK2B0.39965534
124NTRK20.39645175
125GSK3B0.38917347
126CDK90.38808701
127TNIK0.38148253
128CHUK0.37608903
129BTK0.36035726
130WNK30.34869185
131CDK60.34587579
132SGK4940.33733989
133SGK2230.33733989
134DYRK20.33621917
135LATS10.33376679
136DYRK1A0.33220890
137PDK40.33176507
138PDK30.33176507
139RPS6KL10.31940598
140RPS6KC10.31940598
141INSRR0.31312067

Predicted pathways (KEGG)

RankGene SetZ-score
1Mismatch repair_Homo sapiens_hsa034304.00385606
2DNA replication_Homo sapiens_hsa030303.92372906
3Homologous recombination_Homo sapiens_hsa034403.61209683
4Fanconi anemia pathway_Homo sapiens_hsa034603.23955392
5Spliceosome_Homo sapiens_hsa030402.98950167
6Base excision repair_Homo sapiens_hsa034102.92408891
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.72782313
8Non-homologous end-joining_Homo sapiens_hsa034502.66790790
9Nucleotide excision repair_Homo sapiens_hsa034202.63700246
10Cell cycle_Homo sapiens_hsa041102.60671050
11RNA polymerase_Homo sapiens_hsa030202.59649090
12Basal transcription factors_Homo sapiens_hsa030222.41718640
13RNA transport_Homo sapiens_hsa030132.40636862
14Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.30923482
15mRNA surveillance pathway_Homo sapiens_hsa030152.13420777
16Propanoate metabolism_Homo sapiens_hsa006402.12594444
17RNA degradation_Homo sapiens_hsa030182.09059288
18Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.05638780
19Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.95502362
20Ribosome_Homo sapiens_hsa030101.85908707
21Pyrimidine metabolism_Homo sapiens_hsa002401.76289336
22Butanoate metabolism_Homo sapiens_hsa006501.74373552
23Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.68206999
24Selenocompound metabolism_Homo sapiens_hsa004501.64561712
25Protein export_Homo sapiens_hsa030601.61445447
26One carbon pool by folate_Homo sapiens_hsa006701.59921261
27Proteasome_Homo sapiens_hsa030501.58373736
28Phototransduction_Homo sapiens_hsa047441.55763841
29Oxidative phosphorylation_Homo sapiens_hsa001901.44880060
30Steroid biosynthesis_Homo sapiens_hsa001001.40061927
31Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.39800819
32Parkinsons disease_Homo sapiens_hsa050121.38474576
33p53 signaling pathway_Homo sapiens_hsa041151.35057452
34Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.28679435
35Purine metabolism_Homo sapiens_hsa002301.28139786
36Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.27280119
37Systemic lupus erythematosus_Homo sapiens_hsa053221.24315878
38Cysteine and methionine metabolism_Homo sapiens_hsa002701.23704973
39Epstein-Barr virus infection_Homo sapiens_hsa051691.14531015
40Pyruvate metabolism_Homo sapiens_hsa006201.06579115
41Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.06107039
42Oocyte meiosis_Homo sapiens_hsa041141.03021997
43Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.02129471
44Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.97616351
45Primary immunodeficiency_Homo sapiens_hsa053400.97356686
46Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.97340966
47Herpes simplex infection_Homo sapiens_hsa051680.94148967
48Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.90582271
49Transcriptional misregulation in cancer_Homo sapiens_hsa052020.90541947
50Fatty acid elongation_Homo sapiens_hsa000620.90286822
51Alcoholism_Homo sapiens_hsa050340.89453424
52Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.89437368
53Peroxisome_Homo sapiens_hsa041460.88890792
54Nitrogen metabolism_Homo sapiens_hsa009100.86685400
55Viral carcinogenesis_Homo sapiens_hsa052030.86022258
56Caffeine metabolism_Homo sapiens_hsa002320.82782347
57Basal cell carcinoma_Homo sapiens_hsa052170.81931665
58beta-Alanine metabolism_Homo sapiens_hsa004100.79658685
59HTLV-I infection_Homo sapiens_hsa051660.78632657
60Fatty acid metabolism_Homo sapiens_hsa012120.78107344
61Ether lipid metabolism_Homo sapiens_hsa005650.76278416
62Hedgehog signaling pathway_Homo sapiens_hsa043400.74317143
63MicroRNAs in cancer_Homo sapiens_hsa052060.70872856
64Folate biosynthesis_Homo sapiens_hsa007900.70771958
65Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.68762985
66Linoleic acid metabolism_Homo sapiens_hsa005910.68511104
67Alzheimers disease_Homo sapiens_hsa050100.66389682
68Antigen processing and presentation_Homo sapiens_hsa046120.63198383
69Tryptophan metabolism_Homo sapiens_hsa003800.62470194
70Metabolic pathways_Homo sapiens_hsa011000.61759352
71Colorectal cancer_Homo sapiens_hsa052100.61758562
72Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.61085680
73Wnt signaling pathway_Homo sapiens_hsa043100.60611502
74alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.60494375
75Notch signaling pathway_Homo sapiens_hsa043300.60050630
76NF-kappa B signaling pathway_Homo sapiens_hsa040640.59589427
77Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.56121983
78Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.55655840
79Measles_Homo sapiens_hsa051620.55151252
80Olfactory transduction_Homo sapiens_hsa047400.52900201
81Vitamin B6 metabolism_Homo sapiens_hsa007500.52698046
82N-Glycan biosynthesis_Homo sapiens_hsa005100.52027713
83Hippo signaling pathway_Homo sapiens_hsa043900.51664125
84Insulin secretion_Homo sapiens_hsa049110.50339814
85Hematopoietic cell lineage_Homo sapiens_hsa046400.49950483
86SNARE interactions in vesicular transport_Homo sapiens_hsa041300.49657668
87Fatty acid biosynthesis_Homo sapiens_hsa000610.49635340
88Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.48731699
89TGF-beta signaling pathway_Homo sapiens_hsa043500.48376748
90Arginine and proline metabolism_Homo sapiens_hsa003300.47965207
91Prostate cancer_Homo sapiens_hsa052150.46836334
92Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.45375845
93Fatty acid degradation_Homo sapiens_hsa000710.45097555
94Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.44092951
95Huntingtons disease_Homo sapiens_hsa050160.43901716
96Sulfur relay system_Homo sapiens_hsa041220.43420008
972-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.42100057
98Maturity onset diabetes of the young_Homo sapiens_hsa049500.42096376
99Pathways in cancer_Homo sapiens_hsa052000.41698951
100FoxO signaling pathway_Homo sapiens_hsa040680.41410017
101Small cell lung cancer_Homo sapiens_hsa052220.41132748
102Taste transduction_Homo sapiens_hsa047420.40725234
103GABAergic synapse_Homo sapiens_hsa047270.40669505
104Lysine degradation_Homo sapiens_hsa003100.39373686
105Dopaminergic synapse_Homo sapiens_hsa047280.39293144
106Amphetamine addiction_Homo sapiens_hsa050310.38752680
107Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.37900215
108Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.37479571
109Carbon metabolism_Homo sapiens_hsa012000.37181742
110Thyroid cancer_Homo sapiens_hsa052160.36602069
111Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.36536312
112ABC transporters_Homo sapiens_hsa020100.36531937
113Axon guidance_Homo sapiens_hsa043600.36487744
114Influenza A_Homo sapiens_hsa051640.36438447
115Hepatitis B_Homo sapiens_hsa051610.36351387
116Type I diabetes mellitus_Homo sapiens_hsa049400.35052771
117Glutamatergic synapse_Homo sapiens_hsa047240.34540745
118NOD-like receptor signaling pathway_Homo sapiens_hsa046210.34393096
119Primary bile acid biosynthesis_Homo sapiens_hsa001200.34193222
120Intestinal immune network for IgA production_Homo sapiens_hsa046720.33965809
121Cocaine addiction_Homo sapiens_hsa050300.33820636
122Circadian rhythm_Homo sapiens_hsa047100.33166170
123Collecting duct acid secretion_Homo sapiens_hsa049660.32438755
124Melanoma_Homo sapiens_hsa052180.32379252
125Adherens junction_Homo sapiens_hsa045200.32246360
126Endometrial cancer_Homo sapiens_hsa052130.31917180
127Cardiac muscle contraction_Homo sapiens_hsa042600.31403118
128T cell receptor signaling pathway_Homo sapiens_hsa046600.31379409
129Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.30508316
130Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.28933144
131Arachidonic acid metabolism_Homo sapiens_hsa005900.28665649
132Glutathione metabolism_Homo sapiens_hsa004800.28056632
133Biosynthesis of amino acids_Homo sapiens_hsa012300.27574786
134Retinol metabolism_Homo sapiens_hsa008300.26914779
135Allograft rejection_Homo sapiens_hsa053300.26102577
136Sphingolipid metabolism_Homo sapiens_hsa006000.25862221
137Inositol phosphate metabolism_Homo sapiens_hsa005620.25503165
138Autoimmune thyroid disease_Homo sapiens_hsa053200.24881376
139PI3K-Akt signaling pathway_Homo sapiens_hsa041510.24429677
140Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.24250329
141Chronic myeloid leukemia_Homo sapiens_hsa052200.24248363
142Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.24017131
143Thyroid hormone signaling pathway_Homo sapiens_hsa049190.22453238
144Jak-STAT signaling pathway_Homo sapiens_hsa046300.21752801
145Regulation of autophagy_Homo sapiens_hsa041400.21650251
146Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.21470852
147Phosphatidylinositol signaling system_Homo sapiens_hsa040700.20815556
148Vibrio cholerae infection_Homo sapiens_hsa051100.20283952
149B cell receptor signaling pathway_Homo sapiens_hsa046620.19526057
150Apoptosis_Homo sapiens_hsa042100.19165901
151Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.18250111
152Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.16866600
153RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.16836491
154Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.16513932
155Asthma_Homo sapiens_hsa053100.16406416
156Nicotine addiction_Homo sapiens_hsa050330.16119445
157Serotonergic synapse_Homo sapiens_hsa047260.15787572
158Acute myeloid leukemia_Homo sapiens_hsa052210.14254809

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »