BTBD10

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle exocytosis (GO:0016079)5.03133492
2neuron cell-cell adhesion (GO:0007158)5.02596401
3regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.85584341
4synaptic vesicle docking involved in exocytosis (GO:0016081)4.83558076
5pyrimidine nucleobase catabolic process (GO:0006208)4.68883761
6protein localization to synapse (GO:0035418)4.67529950
7regulation of synaptic vesicle exocytosis (GO:2000300)4.62812754
8regulation of short-term neuronal synaptic plasticity (GO:0048172)4.57379881
9glutamate secretion (GO:0014047)4.56129100
10presynaptic membrane assembly (GO:0097105)4.53218007
11positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.41791506
12vocalization behavior (GO:0071625)4.35615215
13regulation of synaptic vesicle transport (GO:1902803)4.21970193
14regulation of glutamate receptor signaling pathway (GO:1900449)4.19133590
15regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.18546065
16glutamate receptor signaling pathway (GO:0007215)4.16349780
17presynaptic membrane organization (GO:0097090)4.15368886
18ionotropic glutamate receptor signaling pathway (GO:0035235)4.08340324
19neuronal action potential propagation (GO:0019227)4.06134964
20synaptic transmission, glutamatergic (GO:0035249)3.99009822
21neurotransmitter-gated ion channel clustering (GO:0072578)3.98737656
22neuron-neuron synaptic transmission (GO:0007270)3.95577088
23positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.90178155
24gamma-aminobutyric acid signaling pathway (GO:0007214)3.87888929
25G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.84203068
26postsynaptic membrane organization (GO:0001941)3.78441865
27response to histamine (GO:0034776)3.74004005
28nucleobase catabolic process (GO:0046113)3.69940885
29long-term synaptic potentiation (GO:0060291)3.59991533
30positive regulation of synapse maturation (GO:0090129)3.58617173
31piRNA metabolic process (GO:0034587)3.56871490
32negative regulation of synaptic transmission, GABAergic (GO:0032229)3.56710185
33cullin deneddylation (GO:0010388)3.54274524
34synaptic vesicle endocytosis (GO:0048488)3.53689451
35positive regulation of neurotransmitter secretion (GO:0001956)3.50672339
36neuron recognition (GO:0008038)3.50344756
37regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.49984262
38regulation of excitatory postsynaptic membrane potential (GO:0060079)3.41281764
39neurofilament cytoskeleton organization (GO:0060052)3.37929681
40cerebellar granule cell differentiation (GO:0021707)3.37110697
41regulation of long-term neuronal synaptic plasticity (GO:0048169)3.35122089
42protein localization to cilium (GO:0061512)3.34552202
43regulation of postsynaptic membrane potential (GO:0060078)3.32659147
44regulation of neurotransmitter secretion (GO:0046928)3.29153794
45regulation of synaptic transmission, glutamatergic (GO:0051966)3.26406217
46axonal fasciculation (GO:0007413)3.24479310
47protein deneddylation (GO:0000338)3.22526499
48regulation of neuronal synaptic plasticity (GO:0048168)3.20816661
49central nervous system projection neuron axonogenesis (GO:0021952)3.20254807
50regulation of synaptic plasticity (GO:0048167)3.18770328
51ganglion development (GO:0061548)3.16181721
52neurotransmitter secretion (GO:0007269)3.15402708
53synaptic vesicle maturation (GO:0016188)3.14633781
54layer formation in cerebral cortex (GO:0021819)3.13106904
55fatty acid elongation (GO:0030497)3.11877493
56startle response (GO:0001964)3.09635338
57energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.08150435
58ATP hydrolysis coupled proton transport (GO:0015991)3.08150435
59long-chain fatty acid biosynthetic process (GO:0042759)3.07955673
60positive regulation of neurotransmitter transport (GO:0051590)3.06868110
61transferrin transport (GO:0033572)3.06440539
62behavioral fear response (GO:0001662)3.04349090
63behavioral defense response (GO:0002209)3.04349090
64regulation of synapse maturation (GO:0090128)3.02826468
65locomotory exploration behavior (GO:0035641)3.02813420
66glial cell proliferation (GO:0014009)3.02715883
67behavioral response to cocaine (GO:0048148)3.02421087
68regulation of glutamate secretion (GO:0014048)3.00549821
69regulation of neurotransmitter transport (GO:0051588)3.00155974
70negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.99804827
71positive regulation of membrane potential (GO:0045838)2.99160395
72membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.98586078
73regulation of vesicle fusion (GO:0031338)2.97874065
74mechanosensory behavior (GO:0007638)2.97357401
75cerebral cortex radially oriented cell migration (GO:0021799)2.96429834
76calcium ion-dependent exocytosis (GO:0017156)2.95905361
77central nervous system neuron axonogenesis (GO:0021955)2.91496798
78organelle transport along microtubule (GO:0072384)2.90906781
79exploration behavior (GO:0035640)2.90667633
80positive regulation of synapse assembly (GO:0051965)2.89775416
81fear response (GO:0042596)2.89067752
82negative regulation of dendrite morphogenesis (GO:0050774)2.87917891
83cerebellar Purkinje cell differentiation (GO:0021702)2.85786643
84proteasome assembly (GO:0043248)2.84006273
85neuron projection extension (GO:1990138)2.83388087
86innervation (GO:0060384)2.83203757
87regulation of dendritic spine morphogenesis (GO:0061001)2.82826935
88ferric iron transport (GO:0015682)2.82464007
89trivalent inorganic cation transport (GO:0072512)2.82464007
90axon extension (GO:0048675)2.82325936
91establishment of melanosome localization (GO:0032401)2.81812291
92membrane depolarization (GO:0051899)2.81157298
93synaptic vesicle transport (GO:0048489)2.80408614
94establishment of synaptic vesicle localization (GO:0097480)2.80408614
95vesicle transport along microtubule (GO:0047496)2.80170907
96calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.79758159
97serotonin metabolic process (GO:0042428)2.78644892
98cerebral cortex cell migration (GO:0021795)2.76343934
99microtubule severing (GO:0051013)2.76219644
100neuronal ion channel clustering (GO:0045161)2.74613117
101retinal cone cell development (GO:0046549)2.74585405
102dendrite development (GO:0016358)2.74508466
103cytoskeleton-dependent intracellular transport (GO:0030705)2.72624750
104regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.72035171
105regulation of meiosis I (GO:0060631)2.70663479
106male meiosis (GO:0007140)2.69964950
107positive regulation of synaptic transmission (GO:0050806)2.69931853
108regulation of synaptic transmission (GO:0050804)2.69899354
109retinal ganglion cell axon guidance (GO:0031290)2.69445583
110melanosome transport (GO:0032402)2.69254375
111regulation of cAMP-dependent protein kinase activity (GO:2000479)2.68809648
112long-term memory (GO:0007616)2.68679498
113DNA double-strand break processing (GO:0000729)2.68594050
114regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315)2.67615204
115righting reflex (GO:0060013)2.67463679
116positive regulation of mitochondrial fission (GO:0090141)2.66699764
117membrane depolarization during action potential (GO:0086010)2.65372916
118establishment of vesicle localization (GO:0051650)2.65234789
119synapse assembly (GO:0007416)2.64761322
120synaptic transmission (GO:0007268)2.64361984
121negative regulation of neurotransmitter transport (GO:0051589)2.63989353
122dendrite morphogenesis (GO:0048813)2.63927424
123neurotransmitter transport (GO:0006836)2.63760818
124cochlea development (GO:0090102)2.63278276
125neural tube formation (GO:0001841)2.63275242
126negative regulation of dendrite development (GO:2000171)2.63237810
127establishment of mitochondrion localization (GO:0051654)2.63166187
128regulation of synapse structural plasticity (GO:0051823)2.62914191
129DNA methylation involved in gamete generation (GO:0043046)2.62691202
130regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.61974400
131learning (GO:0007612)2.61802392
132detection of calcium ion (GO:0005513)2.61459287
133protein heterotetramerization (GO:0051290)2.61003273
134establishment of pigment granule localization (GO:0051905)2.60445410
135positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.59597283
136regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.59050568
137microtubule-based transport (GO:0010970)2.58502334
138establishment of integrated proviral latency (GO:0075713)2.58191194
139ephrin receptor signaling pathway (GO:0048013)2.57306920
140negative regulation of axon guidance (GO:1902668)2.50231229
141pigment granule transport (GO:0051904)2.47487086
142protein polyglutamylation (GO:0018095)2.44054133
143axon cargo transport (GO:0008088)2.43625366
144establishment of nucleus localization (GO:0040023)2.43322998
145melanosome localization (GO:0032400)2.39747186
146membrane budding (GO:0006900)2.39013729
147peptidyl-cysteine modification (GO:0018198)2.37604995
148transmission of nerve impulse (GO:0019226)2.35677710
149gamma-aminobutyric acid transport (GO:0015812)2.35150332
150limb bud formation (GO:0060174)2.34382957
151neuron projection extension involved in neuron projection guidance (GO:1902284)2.34030203
152axon extension involved in axon guidance (GO:0048846)2.34030203
153axonogenesis (GO:0007409)2.33503742
154membrane assembly (GO:0071709)2.32879852
155vesicle localization (GO:0051648)2.32573551
156synapsis (GO:0007129)2.31518376
157regulation of synaptic transmission, GABAergic (GO:0032228)2.29881321
158positive regulation of dendritic spine morphogenesis (GO:0061003)2.29749450
159hippocampus development (GO:0021766)2.29520619
160intraciliary transport (GO:0042073)2.29353088
161dendritic spine organization (GO:0097061)2.28066839
162heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0007157)2.26503059
163regulation of synapse assembly (GO:0051963)2.26193808
164histone H2A acetylation (GO:0043968)2.25746568
165cell migration in hindbrain (GO:0021535)2.25101026
166de novo posttranslational protein folding (GO:0051084)2.23961119

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.76329572
2GBX2_23144817_ChIP-Seq_PC3_Human4.41485235
3SALL1_21062744_ChIP-ChIP_HESCs_Human3.05490731
4TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.75201574
5ZFP57_27257070_Chip-Seq_ESCs_Mouse2.47807556
6TAF15_26573619_Chip-Seq_HEK293_Human2.46817089
7GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.43103614
8REST_21632747_ChIP-Seq_MESCs_Mouse2.42278096
9SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.37597533
10CTBP2_25329375_ChIP-Seq_LNCAP_Human2.37167665
11JARID2_20064375_ChIP-Seq_MESCs_Mouse2.32497183
12NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.30102368
13POU3F2_20337985_ChIP-ChIP_501MEL_Human2.15898980
14FUS_26573619_Chip-Seq_HEK293_Human2.13452105
15SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.12571630
16GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.07069628
17CTBP1_25329375_ChIP-Seq_LNCAP_Human2.04100213
18EZH2_27304074_Chip-Seq_ESCs_Mouse2.02402538
19* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse2.01807377
20SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.00787357
21P300_19829295_ChIP-Seq_ESCs_Human1.91502697
22SMAD4_21799915_ChIP-Seq_A2780_Human1.88340708
23ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.88064225
24VDR_22108803_ChIP-Seq_LS180_Human1.85250687
25EZH2_18974828_ChIP-Seq_MESCs_Mouse1.84281118
26RNF2_18974828_ChIP-Seq_MESCs_Mouse1.84281118
27RNF2_27304074_Chip-Seq_NSC_Mouse1.81550617
28RARB_27405468_Chip-Seq_BRAIN_Mouse1.80278909
29REST_18959480_ChIP-ChIP_MESCs_Mouse1.79954866
30BMI1_23680149_ChIP-Seq_NPCS_Mouse1.79719386
31SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.79433340
32BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.76423585
33JARID2_20075857_ChIP-Seq_MESCs_Mouse1.75796331
34SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.74713439
35IGF1R_20145208_ChIP-Seq_DFB_Human1.72530292
36CBX2_27304074_Chip-Seq_ESCs_Mouse1.70745157
37EED_16625203_ChIP-ChIP_MESCs_Mouse1.68568602
38WT1_19549856_ChIP-ChIP_CCG9911_Human1.66854723
39SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.66432780
40MTF2_20144788_ChIP-Seq_MESCs_Mouse1.65472000
41FLI1_27457419_Chip-Seq_LIVER_Mouse1.64335230
42RBPJ_22232070_ChIP-Seq_NCS_Mouse1.64290439
43RNF2_27304074_Chip-Seq_ESCs_Mouse1.63781386
44SMAD_19615063_ChIP-ChIP_OVARY_Human1.58493167
45TOP2B_26459242_ChIP-Seq_MCF-7_Human1.53217753
46SUZ12_27294783_Chip-Seq_ESCs_Mouse1.49031173
47EZH2_27294783_Chip-Seq_ESCs_Mouse1.49016195
48NANOG_18555785_Chip-Seq_ESCs_Mouse1.48683896
49CDX2_19796622_ChIP-Seq_MESCs_Mouse1.47363903
50PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.46196171
51ELK1_19687146_ChIP-ChIP_HELA_Human1.45937173
52STAT3_23295773_ChIP-Seq_U87_Human1.45705856
53SMAD3_21741376_ChIP-Seq_EPCs_Human1.45638548
54PCGF2_27294783_Chip-Seq_ESCs_Mouse1.45369204
55PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.44682847
56TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.44657820
57AR_25329375_ChIP-Seq_VCAP_Human1.42151239
58OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.42077403
59SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.41394719
60AR_21572438_ChIP-Seq_LNCaP_Human1.40023823
61ER_23166858_ChIP-Seq_MCF-7_Human1.38668535
62EWS_26573619_Chip-Seq_HEK293_Human1.38511562
63UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.36427446
64CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.36249241
65CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.35707097
66* TP53_18474530_ChIP-ChIP_U2OS_Human1.35491809
67CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.35084532
68MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.33764351
69PIAS1_25552417_ChIP-Seq_VCAP_Human1.33517720
70KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.32084131
71NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.32063690
72KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.32034990
73SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.31876299
74AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.31635369
75TCF4_23295773_ChIP-Seq_U87_Human1.31256988
76CBP_20019798_ChIP-Seq_JUKART_Human1.30978646
77IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.30978646
78EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.30306258
79HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.27145315
80RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.26633720
81MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.26357299
82JUN_21703547_ChIP-Seq_K562_Human1.25930177
83KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.25849576
84DROSHA_22980978_ChIP-Seq_HELA_Human1.25618017
85GABP_17652178_ChIP-ChIP_JURKAT_Human1.24459815
86NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.24318305
87NRF2_20460467_ChIP-Seq_MEFs_Mouse1.24318305
88ZNF274_21170338_ChIP-Seq_K562_Hela1.23046780
89IKZF1_21737484_ChIP-ChIP_HCT116_Human1.22953801
90* E2F1_18555785_Chip-Seq_ESCs_Mouse1.21642792
91SOX2_21211035_ChIP-Seq_LN229_Gbm1.21578590
92MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.20821654
93POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.20711748
94TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.20711748
95NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.20072794
96P53_22387025_ChIP-Seq_ESCs_Mouse1.19992012
97TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.19795703
98FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.19004664
99PRDM14_20953172_ChIP-Seq_ESCs_Human1.18298897
100CMYC_18555785_Chip-Seq_ESCs_Mouse1.18007149
101P53_22127205_ChIP-Seq_FIBROBLAST_Human1.16257460
102PADI4_21655091_ChIP-ChIP_MCF-7_Human1.15894202
103RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.14738164
104RUNX2_22187159_ChIP-Seq_PCA_Human1.14711888
105BCAT_22108803_ChIP-Seq_LS180_Human1.14424494
106SOX9_26525672_Chip-Seq_HEART_Mouse1.12962106
107NR3C1_21868756_ChIP-Seq_MCF10A_Human1.12796092
108* MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.12393818
109GATA1_26923725_Chip-Seq_HPCs_Mouse1.11921905
110MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.11820954
111YAP1_20516196_ChIP-Seq_MESCs_Mouse1.11534843
112EP300_21415370_ChIP-Seq_HL-1_Mouse1.11268651
113TBX3_20139965_ChIP-Seq_MESCs_Mouse1.11063064
114NR3C1_23031785_ChIP-Seq_PC12_Mouse1.10663244
115HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.10477182
116TBX3_20139965_ChIP-Seq_ESCs_Mouse1.10373208
117EZH2_27294783_Chip-Seq_NPCs_Mouse1.10356422
118POU5F1_16153702_ChIP-ChIP_HESCs_Human1.09719807
119SUZ12_27294783_Chip-Seq_NPCs_Mouse1.09177113
120EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.09148923
121TP53_16413492_ChIP-PET_HCT116_Human1.08897725
122TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.08509482
123TAL1_26923725_Chip-Seq_HPCs_Mouse1.08434046
124SUZ12_18555785_Chip-Seq_ESCs_Mouse1.08285279
125KDM2B_26808549_Chip-Seq_REH_Human1.08207436
126TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07840817
127CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.07837211
128SOX2_18555785_Chip-Seq_ESCs_Mouse1.07651405
129STAT3_18555785_Chip-Seq_ESCs_Mouse1.07096307
130ZNF217_24962896_ChIP-Seq_MCF-7_Human1.05753320
131KLF5_20875108_ChIP-Seq_MESCs_Mouse1.04180998
132PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.03875002
133CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.02773328
134STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.02452160
135PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.02055045
136LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00832438
137FLI1_21867929_ChIP-Seq_TH2_Mouse1.00396844
138TCF4_22108803_ChIP-Seq_LS180_Human0.98393102

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern5.53755631
2MP0004859_abnormal_synaptic_plasticity4.94142098
3MP0003635_abnormal_synaptic_transmissio3.56408449
4MP0004270_analgesia3.16885164
5MP0001968_abnormal_touch/_nociception3.10697734
6MP0002063_abnormal_learning/memory/cond3.08102673
7MP0009745_abnormal_behavioral_response3.01451190
8MP0002736_abnormal_nociception_after2.87972029
9MP0009046_muscle_twitch2.85123507
10MP0002064_seizures2.75833467
11MP0002572_abnormal_emotion/affect_behav2.71982741
12MP0008877_abnormal_DNA_methylation2.57859064
13MP0002734_abnormal_mechanical_nocicepti2.50295859
14MP0006054_spinal_hemorrhage2.43597614
15MP0002272_abnormal_nervous_system2.33604260
16MP0000569_abnormal_digit_pigmentation2.33007258
17MP0001486_abnormal_startle_reflex2.31964664
18MP0003787_abnormal_imprinting2.29988485
19MP0001984_abnormal_olfaction2.28503082
20MP0002735_abnormal_chemical_nociception2.23811856
21MP0001440_abnormal_grooming_behavior2.22650025
22MP0001501_abnormal_sleep_pattern2.08696578
23MP0001529_abnormal_vocalization2.05136651
24MP0005423_abnormal_somatic_nervous2.04056709
25MP0002067_abnormal_sensory_capabilities1.96158184
26MP0000778_abnormal_nervous_system1.94543488
27MP0005248_abnormal_Harderian_gland1.90638264
28MP0001188_hyperpigmentation1.86651616
29MP0005646_abnormal_pituitary_gland1.84369579
30MP0002184_abnormal_innervation1.83592790
31MP0006276_abnormal_autonomic_nervous1.78296373
32MP0003879_abnormal_hair_cell1.75252751
33MP0001970_abnormal_pain_threshold1.72018734
34MP0002733_abnormal_thermal_nociception1.71608459
35MP0003221_abnormal_cardiomyocyte_apopto1.65267739
36MP0005386_behavior/neurological_phenoty1.64330635
37MP0004924_abnormal_behavior1.64330635
38MP0001905_abnormal_dopamine_level1.62439010
39MP0002557_abnormal_social/conspecific_i1.60299489
40MP0002102_abnormal_ear_morphology1.53934970
41MP0002653_abnormal_ependyma_morphology1.52048416
42MP0005410_abnormal_fertilization1.50678855
43MP0001177_atelectasis1.46026970
44MP0010368_abnormal_lymphatic_system1.44472790
45MP0010386_abnormal_urinary_bladder1.43962532
46MP0001299_abnormal_eye_distance/1.40944375
47MP0004811_abnormal_neuron_physiology1.40737378
48MP0005623_abnormal_meninges_morphology1.38257190
49MP0008058_abnormal_DNA_repair1.37453684
50MP0002751_abnormal_autonomic_nervous1.35993189
51MP0000647_abnormal_sebaceous_gland1.31100632
52MP0002882_abnormal_neuron_morphology1.30220097
53MP0008569_lethality_at_weaning1.29362051
54MP0003329_amyloid_beta_deposits1.29193749
55MP0005645_abnormal_hypothalamus_physiol1.28270595
56MP0000955_abnormal_spinal_cord1.27969492
57MP0001502_abnormal_circadian_rhythm1.26272670
58MP0003122_maternal_imprinting1.25796163
59MP0002234_abnormal_pharynx_morphology1.25661892
60MP0006292_abnormal_olfactory_placode1.24075379
61MP0002066_abnormal_motor_capabilities/c1.23127978
62MP0001879_abnormal_lymphatic_vessel1.21464220
63MP0005187_abnormal_penis_morphology1.21060272
64MP0003698_abnormal_male_reproductive1.20616504
65MP0002876_abnormal_thyroid_physiology1.19606286
66MP0005551_abnormal_eye_electrophysiolog1.18654257
67MP0000427_abnormal_hair_cycle1.16965824
68MP0010234_abnormal_vibrissa_follicle1.16297946
69MP0002090_abnormal_vision1.16193660
70MP0003941_abnormal_skin_development1.15022577
71MP0003385_abnormal_body_wall1.13638946
72MP0004742_abnormal_vestibular_system1.13316154
73MP0003121_genomic_imprinting1.13119905
74MP0002837_dystrophic_cardiac_calcinosis1.09582320
75MP0002152_abnormal_brain_morphology1.08490524
76MP0004142_abnormal_muscle_tone1.07698453
77MP0005394_taste/olfaction_phenotype1.07341976
78MP0005499_abnormal_olfactory_system1.07341976
79MP0000631_abnormal_neuroendocrine_gland1.07318533
80MP0005171_absent_coat_pigmentation1.06531051
81MP0000579_abnormal_nail_morphology1.06470755
82MP0001963_abnormal_hearing_physiology1.06219237
83MP0001929_abnormal_gametogenesis1.05695516
84MP0009780_abnormal_chondrocyte_physiolo1.02769486
85MP0002638_abnormal_pupillary_reflex1.02477396
86MP0002233_abnormal_nose_morphology0.97366598
87MP0009697_abnormal_copulation0.94039205
88MP0003646_muscle_fatigue0.94015086
89MP0010678_abnormal_skin_adnexa0.93561134
90MP0003123_paternal_imprinting0.91444381
91MP0002177_abnormal_outer_ear0.90089223
92MP0002752_abnormal_somatic_nervous0.89990094
93MP0000516_abnormal_urinary_system0.89370962
94MP0005367_renal/urinary_system_phenotyp0.89370962
95MP0004858_abnormal_nervous_system0.89129925
96MP0003755_abnormal_palate_morphology0.88221160
97MP0008932_abnormal_embryonic_tissue0.87813918
98MP0003631_nervous_system_phenotype0.87772593
99MP0001485_abnormal_pinna_reflex0.86860978
100MP0006072_abnormal_retinal_apoptosis0.86685310
101MP0003633_abnormal_nervous_system0.85340726
102MP0002210_abnormal_sex_determination0.85274633
103MP0004145_abnormal_muscle_electrophysio0.84790280
104MP0000358_abnormal_cell_content/0.84406158
105MP0004272_abnormal_basement_membrane0.84078655
106MP0002332_abnormal_exercise_endurance0.82991456
107MP0002229_neurodegeneration0.82580138
108MP0002161_abnormal_fertility/fecundity0.80666993
109MP0006035_abnormal_mitochondrial_morpho0.80007438
110MP0003119_abnormal_digestive_system0.79530301
111MP0003861_abnormal_nervous_system0.78072928
112MP0002822_catalepsy0.75211807
113MP0000026_abnormal_inner_ear0.74957687
114MP0004233_abnormal_muscle_weight0.74571878
115MP0005084_abnormal_gallbladder_morpholo0.74511685
116MP0008789_abnormal_olfactory_epithelium0.73395713
117MP0002081_perinatal_lethality0.73395587
118MP0004484_altered_response_of0.73232405
119MP0002909_abnormal_adrenal_gland0.73010585
120MP0003718_maternal_effect0.70790210
121MP0004885_abnormal_endolymph0.69751794
122MP0000653_abnormal_sex_gland0.68510383
123MP0000015_abnormal_ear_pigmentation0.66755230
124MP0003937_abnormal_limbs/digits/tail_de0.66425512
125MP0002069_abnormal_eating/drinking_beha0.66285664
126MP0000383_abnormal_hair_follicle0.66063713
127MP0003632_abnormal_nervous_system0.65564000
128MP0003890_abnormal_embryonic-extraembry0.65292344
129MP0004215_abnormal_myocardial_fiber0.64678806
130MP0008260_abnormal_autophagy0.63734571
131MP0008872_abnormal_physiological_respon0.63013015
132MP0002160_abnormal_reproductive_system0.62874050
133MP0004085_abnormal_heartbeat0.62472284
134MP0001145_abnormal_male_reproductive0.61915478
135MP0002163_abnormal_gland_morphology0.61695953
136MP0000751_myopathy0.61610782
137MP0000013_abnormal_adipose_tissue0.60363340
138MP0005253_abnormal_eye_physiology0.59378304

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.79611377
2Epileptic encephalopathy (HP:0200134)5.10027095
3Atonic seizures (HP:0010819)4.74434158
4Focal seizures (HP:0007359)4.52631492
5Febrile seizures (HP:0002373)4.28910211
6Myokymia (HP:0002411)4.06620007
7Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.70140258
8Absence seizures (HP:0002121)3.57972022
9Hyperventilation (HP:0002883)3.53612751
10Absent/shortened dynein arms (HP:0200106)3.52427763
11Dynein arm defect of respiratory motile cilia (HP:0012255)3.52427763
12Visual hallucinations (HP:0002367)3.42870657
13Gait imbalance (HP:0002141)3.36950989
14Dialeptic seizures (HP:0011146)3.29722339
15Medial flaring of the eyebrow (HP:0010747)3.27090368
16Progressive cerebellar ataxia (HP:0002073)3.22361908
17Generalized tonic-clonic seizures (HP:0002069)3.14108961
18Congenital primary aphakia (HP:0007707)3.13460590
19Atrophy/Degeneration involving motor neurons (HP:0007373)3.09077906
20Abnormality of the hip-girdle musculature (HP:0001445)3.06621878
21Abnormality of the musculature of the pelvis (HP:0001469)3.06621878
22Broad-based gait (HP:0002136)3.05125927
23Cortical dysplasia (HP:0002539)3.03299000
24Abnormal hair whorl (HP:0010721)3.03151045
25Amblyopia (HP:0000646)3.00569720
26Abnormality of the labia minora (HP:0012880)2.98519002
27Nephrogenic diabetes insipidus (HP:0009806)2.96483585
28Abnormal respiratory motile cilium physiology (HP:0012261)2.87081099
29Gaze-evoked nystagmus (HP:0000640)2.81805740
30Volvulus (HP:0002580)2.70879574
31Drooling (HP:0002307)2.68714988
32Excessive salivation (HP:0003781)2.68714988
33Impaired vibration sensation in the lower limbs (HP:0002166)2.62478173
34Insidious onset (HP:0003587)2.61594152
35Termporal pattern (HP:0011008)2.61594152
36Abnormal ciliary motility (HP:0012262)2.61373808
37Poor coordination (HP:0002370)2.59070587
38Abnormal respiratory motile cilium morphology (HP:0005938)2.56567944
39Abnormal respiratory epithelium morphology (HP:0012253)2.56567944
40Inability to walk (HP:0002540)2.56410018
41Lissencephaly (HP:0001339)2.49729983
42Pelvic girdle muscle weakness (HP:0003749)2.48859564
43Epileptiform EEG discharges (HP:0011182)2.40493293
44Lower limb muscle weakness (HP:0007340)2.39413252
45Genital tract atresia (HP:0001827)2.39231739
46Hypoplastic pelvis (HP:0008839)2.38128445
47Shoulder girdle muscle weakness (HP:0003547)2.36000115
48Spastic gait (HP:0002064)2.34653870
49Rhinitis (HP:0012384)2.33115521
50Vaginal atresia (HP:0000148)2.32905939
51Thyroid carcinoma (HP:0002890)2.29314108
52Truncal ataxia (HP:0002078)2.29002150
53Progressive inability to walk (HP:0002505)2.25673776
54Abnormal eating behavior (HP:0100738)2.23688884
55Protruding tongue (HP:0010808)2.22739217
56Fetal akinesia sequence (HP:0001989)2.21713889
57Stenosis of the external auditory canal (HP:0000402)2.21693848
58Aplasia/Hypoplasia of the brainstem (HP:0007362)2.19290294
59Hypoplasia of the brainstem (HP:0002365)2.19290294
60Specific learning disability (HP:0001328)2.18892654
61Abnormality of the anterior horn cell (HP:0006802)2.18793560
62Degeneration of anterior horn cells (HP:0002398)2.18793560
63Poor eye contact (HP:0000817)2.17776299
64Pancreatic fibrosis (HP:0100732)2.17037970
65Hand muscle atrophy (HP:0009130)2.14961079
66Polyphagia (HP:0002591)2.14337970
67Short tibia (HP:0005736)2.14234893
68Split foot (HP:0001839)2.14166738
69Abnormality of the lower motor neuron (HP:0002366)2.14009259
70Impaired smooth pursuit (HP:0007772)2.13090916
71Abnormality of the astrocytes (HP:0100707)2.07999997
72Astrocytoma (HP:0009592)2.07999997
73Absent speech (HP:0001344)2.07679672
74Limb dystonia (HP:0002451)2.07339060
75Hemiparesis (HP:0001269)2.06552657
76Urinary bladder sphincter dysfunction (HP:0002839)2.05664685
77EEG with generalized epileptiform discharges (HP:0011198)2.02690199
78Medulloblastoma (HP:0002885)2.02223809
79Infertility (HP:0000789)2.00528899
80Apathy (HP:0000741)2.00214751
81Dysdiadochokinesis (HP:0002075)1.99680073
82Abnormality of the corticospinal tract (HP:0002492)1.98553890
83Dysmetria (HP:0001310)1.95875624
84Delayed gross motor development (HP:0002194)1.95300084
85Aplasia/Hypoplasia of the tibia (HP:0005772)1.94758714
86Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.94577523
87Degeneration of the lateral corticospinal tracts (HP:0002314)1.94577523
88Thickened helices (HP:0000391)1.94068396
89Abnormality of the motor neurons (HP:0002450)1.93719910
90Abnormal neuron morphology (HP:0012757)1.93719910
91Diminished motivation (HP:0000745)1.93572661
92Aplasia/Hypoplasia of the lens (HP:0008063)1.93252743
93Ependymoma (HP:0002888)1.91838742
94Labial hypoplasia (HP:0000066)1.91730510
95Nephronophthisis (HP:0000090)1.90374517
96Abnormality of ocular smooth pursuit (HP:0000617)1.89870892
97Delusions (HP:0000746)1.88571569
98Intention tremor (HP:0002080)1.87975208
99Abnormality of midbrain morphology (HP:0002418)1.87843807
100Molar tooth sign on MRI (HP:0002419)1.87843807
101Scanning speech (HP:0002168)1.86989323
102Oligodactyly (hands) (HP:0001180)1.85996897
103Abnormality of salivation (HP:0100755)1.85321549
104Pachygyria (HP:0001302)1.84343292
105Limb-girdle muscle weakness (HP:0003325)1.84149192
106Pheochromocytoma (HP:0002666)1.83806511
107Hypoplastic female external genitalia (HP:0012815)1.83469284
108Optic nerve hypoplasia (HP:0000609)1.83277720
109Genetic anticipation (HP:0003743)1.82425191
110Abnormal auditory evoked potentials (HP:0006958)1.81476428
111Mutism (HP:0002300)1.80838167
112Papillary thyroid carcinoma (HP:0002895)1.80492280
113Urinary urgency (HP:0000012)1.78941548
114Impaired vibratory sensation (HP:0002495)1.78713298
115Hypsarrhythmia (HP:0002521)1.78192198
116Hip dysplasia (HP:0001385)1.76832135
117Esotropia (HP:0000565)1.76142417
118Stereotypic behavior (HP:0000733)1.75709648
119Incomplete penetrance (HP:0003829)1.74485794
120Abnormality of the labia (HP:0000058)1.73853829
121Retinal dysplasia (HP:0007973)1.72665900
122Chronic bronchitis (HP:0004469)1.71505473
123Spastic tetraplegia (HP:0002510)1.70664423
124Broad foot (HP:0001769)1.69415544
125Horizontal nystagmus (HP:0000666)1.68909345
126Abnormality of the metopic suture (HP:0005556)1.68208401
127Spinal muscular atrophy (HP:0007269)1.67692323
128Depression (HP:0000716)1.67230125
129Curly hair (HP:0002212)1.67157189
130Generalized myoclonic seizures (HP:0002123)1.66174476
131Tetraparesis (HP:0002273)1.65928366
132Acute necrotizing encephalopathy (HP:0006965)1.65386230
133Autoamputation (HP:0001218)1.65094039
134Amyotrophic lateral sclerosis (HP:0007354)1.64895588
135Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.64828761
136Abnormality of binocular vision (HP:0011514)1.64804484
137Diplopia (HP:0000651)1.64804484
138Postaxial hand polydactyly (HP:0001162)1.63664457
139Gastroesophageal reflux (HP:0002020)1.63096690
140Action tremor (HP:0002345)1.62723692
141Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.62572504
142Abnormality of alanine metabolism (HP:0010916)1.62572504
143Hyperalaninemia (HP:0003348)1.62572504
144Failure to thrive in infancy (HP:0001531)1.62433671
145Ankle clonus (HP:0011448)1.61684620
146Impaired social interactions (HP:0000735)1.61250863
147Abnormal social behavior (HP:0012433)1.61250863
148Gait ataxia (HP:0002066)1.60828062
149Microglossia (HP:0000171)1.60616075
150Heterotopia (HP:0002282)1.60012221
151Atrophic scars (HP:0001075)1.59787297
152Limb-girdle muscle atrophy (HP:0003797)1.58044403

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK4.37224516
2TRIM283.96020861
3EPHA43.69544235
4NTRK33.67082420
5MAP3K43.41404552
6MAP2K73.23548363
7MAP3K92.78004830
8PLK22.60928541
9MAP3K122.52170160
10CDK192.28517617
11BMPR22.20635097
12DAPK22.16416733
13CCNB12.15396396
14SRPK12.10544013
15KSR12.06250799
16RIPK42.00629794
17MINK11.97847314
18DAPK11.90578123
19MARK11.88065310
20MAP2K41.77289614
21PNCK1.74967606
22PAK61.74433628
23MAPK131.68626723
24KSR21.65656335
25PRKD31.63753994
26CSNK1G31.60982947
27ARAF1.59746865
28AKT31.59237256
29CSNK1A1L1.54159777
30MET1.49962757
31PRPF4B1.47382931
32EIF2AK31.46320562
33LIMK11.43304782
34CSNK1G11.40811121
35BRAF1.39622927
36TIE11.37606253
37PDK41.35213966
38PDK31.35213966
39OXSR11.34937989
40MAP4K21.31944272
41TESK11.25838742
42LATS21.23498599
43GRK51.23431603
44PBK1.20637814
45PTK2B1.18984122
46NTRK21.11976232
47MAP3K61.10431656
48RAF11.09084477
49BUB11.07838058
50EPHB21.06516173
51SIK31.06159793
52CDK51.04551693
53CAMK2A1.02823346
54BCR1.02565987
55MOS0.99460394
56PRKCG0.97090680
57CAMKK20.96505557
58EIF2AK10.95289728
59RPS6KA40.93692962
60CDK180.91895943
61NME10.91482320
62FER0.89924521
63TNIK0.88263027
64PLK30.87680960
65MAP3K130.83937192
66DYRK1A0.83915371
67CDK150.83216420
68CDK80.82939599
69CDK140.81167977
70CAMK2B0.78478942
71SGK4940.78377665
72SGK2230.78377665
73ROCK20.77361278
74SGK20.77199301
75STK240.76009412
76WNK30.75009330
77PDK20.74350990
78DYRK30.73911675
79BMPR1B0.72780197
80YES10.71872318
81TSSK60.70687176
82CDK11A0.69631100
83CAMKK10.65557321
84STK380.64055995
85FGR0.62535073
86PLK10.62365571
87CDC70.57349504
88MST40.56792003
89PKN10.55978597
90CDK30.55699944
91TAOK10.55462003
92STK110.55094574
93CSNK1G20.52654624
94STK38L0.52498295
95SGK10.52081121
96MUSK0.51620401
97PRKCE0.51004101
98DYRK20.50985058
99MAP3K20.49633097
100NTRK10.47698543
101BRSK10.47093220
102NEK60.46821061
103PINK10.46572333
104NEK10.46317194
105PAK30.45379742
106ROCK10.45358401
107ADRBK10.44569784
108ADRBK20.43654030
109TTK0.43327340
110EGFR0.42375657
111MAPKAPK50.41664737
112PTK20.41632064
113NUAK10.40528924
114UHMK10.39161058
115MAP2K10.38610518
116ACVR1B0.37447635
117CHEK20.36793384
118SIK20.36765436
119EPHB10.35160265
120PLK40.34575024
121PAK40.34344250
122MKNK10.33892998
123EPHA30.33491982
124CSNK1D0.31074969
125FES0.30076733
126ERBB40.29973975
127MKNK20.29668757
128NEK90.29362490
129CAMK2D0.28331592
130CAMK2G0.28283453
131CSNK1E0.28260654
132TYRO30.27961534
133BRD40.27674326
134MARK20.27136417
135PRKCI0.26520454
136CAMK10.26508505
137PDK10.26427090
138AURKA0.26330739
139ERBB30.25037447
140MAP3K50.24604498

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.96308057
2Synaptic vesicle cycle_Homo sapiens_hsa047213.43662000
3Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.71465036
4Long-term potentiation_Homo sapiens_hsa047202.70832103
5Collecting duct acid secretion_Homo sapiens_hsa049662.66663997
6Olfactory transduction_Homo sapiens_hsa047402.63112151
7Amphetamine addiction_Homo sapiens_hsa050312.51209200
8Circadian entrainment_Homo sapiens_hsa047132.45640600
9Protein export_Homo sapiens_hsa030602.40497438
10Morphine addiction_Homo sapiens_hsa050322.38761650
11Glutamatergic synapse_Homo sapiens_hsa047242.35837649
12Pathogenic Escherichia coli infection_Homo sapiens_hsa051302.32220480
13GABAergic synapse_Homo sapiens_hsa047272.15480066
14Dopaminergic synapse_Homo sapiens_hsa047282.10159074
15Steroid biosynthesis_Homo sapiens_hsa001002.04351306
16Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.01569747
17Taste transduction_Homo sapiens_hsa047421.90378994
18Serotonergic synapse_Homo sapiens_hsa047261.84750004
19Salivary secretion_Homo sapiens_hsa049701.84326169
20Insulin secretion_Homo sapiens_hsa049111.72693714
21Renin secretion_Homo sapiens_hsa049241.71065751
22Long-term depression_Homo sapiens_hsa047301.69567450
23Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.68704498
24Vibrio cholerae infection_Homo sapiens_hsa051101.65021191
25Oocyte meiosis_Homo sapiens_hsa041141.58406293
26Oxytocin signaling pathway_Homo sapiens_hsa049211.56015906
27Cholinergic synapse_Homo sapiens_hsa047251.51837668
28Calcium signaling pathway_Homo sapiens_hsa040201.49050622
29Gastric acid secretion_Homo sapiens_hsa049711.46887154
30Fatty acid elongation_Homo sapiens_hsa000621.45399273
31Phototransduction_Homo sapiens_hsa047441.43835405
32Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.41566968
33Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.40163311
34Non-homologous end-joining_Homo sapiens_hsa034501.36739190
35Aldosterone synthesis and secretion_Homo sapiens_hsa049251.36651325
36Cocaine addiction_Homo sapiens_hsa050301.35523167
37GnRH signaling pathway_Homo sapiens_hsa049121.34757317
38Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.32583388
39Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.29645658
40Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.29589489
41Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.22376336
42Gap junction_Homo sapiens_hsa045401.16540634
43Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.16441086
44Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.13511747
45Oxidative phosphorylation_Homo sapiens_hsa001901.10500706
46cAMP signaling pathway_Homo sapiens_hsa040241.07808394
47Phosphatidylinositol signaling system_Homo sapiens_hsa040701.06481141
48Circadian rhythm_Homo sapiens_hsa047101.03234070
49Axon guidance_Homo sapiens_hsa043601.02805283
50Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.01454087
51Hippo signaling pathway_Homo sapiens_hsa043900.97946723
52Estrogen signaling pathway_Homo sapiens_hsa049150.97625779
53Dorso-ventral axis formation_Homo sapiens_hsa043200.96239907
54cGMP-PKG signaling pathway_Homo sapiens_hsa040220.94143867
55Tight junction_Homo sapiens_hsa045300.93498990
56Cardiac muscle contraction_Homo sapiens_hsa042600.92592624
57Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.91997333
58ErbB signaling pathway_Homo sapiens_hsa040120.90609584
59Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.89721679
60Basal transcription factors_Homo sapiens_hsa030220.89039273
61Propanoate metabolism_Homo sapiens_hsa006400.88452739
62Alzheimers disease_Homo sapiens_hsa050100.88047842
63Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.87920679
64Adherens junction_Homo sapiens_hsa045200.87626595
65Rheumatoid arthritis_Homo sapiens_hsa053230.87432536
66Glioma_Homo sapiens_hsa052140.86568149
67Vascular smooth muscle contraction_Homo sapiens_hsa042700.85182170
68Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.84933807
69Melanogenesis_Homo sapiens_hsa049160.84309462
70Huntingtons disease_Homo sapiens_hsa050160.83257309
71Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.82160112
72Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.79678036
73MAPK signaling pathway_Homo sapiens_hsa040100.79423864
74RNA transport_Homo sapiens_hsa030130.78774317
75Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.78166148
76Shigellosis_Homo sapiens_hsa051310.74332375
77Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.73019637
78Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.71586930
79Ras signaling pathway_Homo sapiens_hsa040140.68885932
80Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.64641851
81Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.63868045
82p53 signaling pathway_Homo sapiens_hsa041150.63095586
83SNARE interactions in vesicular transport_Homo sapiens_hsa041300.62679922
84Mismatch repair_Homo sapiens_hsa034300.62374269
85Alcoholism_Homo sapiens_hsa050340.61664120
86Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.61521428
87Choline metabolism in cancer_Homo sapiens_hsa052310.61487632
88Parkinsons disease_Homo sapiens_hsa050120.60692613
89Ovarian steroidogenesis_Homo sapiens_hsa049130.59831939
90Nucleotide excision repair_Homo sapiens_hsa034200.59096549
91Type II diabetes mellitus_Homo sapiens_hsa049300.58441695
92Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.56291007
93Inositol phosphate metabolism_Homo sapiens_hsa005620.56277904
94Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.56262595
95VEGF signaling pathway_Homo sapiens_hsa043700.54714999
96Glucagon signaling pathway_Homo sapiens_hsa049220.54162147
97Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.54044090
98Salmonella infection_Homo sapiens_hsa051320.53977699
99Wnt signaling pathway_Homo sapiens_hsa043100.53268198
100Phagosome_Homo sapiens_hsa041450.52736300
101Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.51697571
102Type I diabetes mellitus_Homo sapiens_hsa049400.51684290
103Pancreatic secretion_Homo sapiens_hsa049720.50871317
104Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.50243981
105Regulation of actin cytoskeleton_Homo sapiens_hsa048100.49982355
106Renal cell carcinoma_Homo sapiens_hsa052110.48169828
107RNA degradation_Homo sapiens_hsa030180.47416128
1082-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.47356960
109Phospholipase D signaling pathway_Homo sapiens_hsa040720.47085002
110Colorectal cancer_Homo sapiens_hsa052100.46074679
111Regulation of autophagy_Homo sapiens_hsa041400.45412414
112Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.45239352
113RNA polymerase_Homo sapiens_hsa030200.45009650
114Dilated cardiomyopathy_Homo sapiens_hsa054140.44729030
115TGF-beta signaling pathway_Homo sapiens_hsa043500.43951061
116Sulfur metabolism_Homo sapiens_hsa009200.43265296
117mRNA surveillance pathway_Homo sapiens_hsa030150.43065004
118Rap1 signaling pathway_Homo sapiens_hsa040150.40345464
119Sphingolipid signaling pathway_Homo sapiens_hsa040710.39855732
120Cell cycle_Homo sapiens_hsa041100.38898368
121Thyroid hormone signaling pathway_Homo sapiens_hsa049190.38142480
122Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.37957008
123Fanconi anemia pathway_Homo sapiens_hsa034600.37793337
124Fatty acid biosynthesis_Homo sapiens_hsa000610.37366176
125Thyroid hormone synthesis_Homo sapiens_hsa049180.37076500
126Neurotrophin signaling pathway_Homo sapiens_hsa047220.36017497
127African trypanosomiasis_Homo sapiens_hsa051430.33015225
128Ether lipid metabolism_Homo sapiens_hsa005650.32229385
129Purine metabolism_Homo sapiens_hsa002300.31653022
130Melanoma_Homo sapiens_hsa052180.30660176
131Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.28437389
132Endocytosis_Homo sapiens_hsa041440.26678003
133mTOR signaling pathway_Homo sapiens_hsa041500.25554582
134FoxO signaling pathway_Homo sapiens_hsa040680.25143962
135Hedgehog signaling pathway_Homo sapiens_hsa043400.24738708
136Proteasome_Homo sapiens_hsa030500.24246172

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