Rank | Gene Set | Z-score |
---|---|---|
1 | locomotory exploration behavior (GO:0035641) | 5.83235108 |
2 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 5.70404516 |
3 | synaptic vesicle maturation (GO:0016188) | 5.58351091 |
4 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 5.19373583 |
5 | vocalization behavior (GO:0071625) | 5.16506794 |
6 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 5.16354671 |
7 | neuronal action potential propagation (GO:0019227) | 5.12332410 |
8 | glutamate secretion (GO:0014047) | 4.97189724 |
9 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 4.93236142 |
10 | synaptic vesicle exocytosis (GO:0016079) | 4.90946000 |
11 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 4.86309821 |
12 | regulation of synaptic vesicle exocytosis (GO:2000300) | 4.61179209 |
13 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 4.55695382 |
14 | glutamate receptor signaling pathway (GO:0007215) | 4.49846595 |
15 | cerebellar granule cell differentiation (GO:0021707) | 4.47475084 |
16 | regulation of glutamate receptor signaling pathway (GO:1900449) | 4.45742961 |
17 | cellular potassium ion homeostasis (GO:0030007) | 4.45448567 |
18 | exploration behavior (GO:0035640) | 4.39606539 |
19 | synaptic transmission, glutamatergic (GO:0035249) | 4.38871794 |
20 | neurotransmitter secretion (GO:0007269) | 4.25195073 |
21 | gamma-aminobutyric acid transport (GO:0015812) | 4.25101696 |
22 | sodium ion export (GO:0071436) | 4.24838074 |
23 | regulation of neuronal synaptic plasticity (GO:0048168) | 4.11214178 |
24 | cerebellar Purkinje cell differentiation (GO:0021702) | 4.05978790 |
25 | positive regulation of synapse maturation (GO:0090129) | 4.03865929 |
26 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 4.03439836 |
27 | protein localization to synapse (GO:0035418) | 4.03124927 |
28 | regulation of synaptic vesicle transport (GO:1902803) | 4.03014930 |
29 | long-term memory (GO:0007616) | 4.00375567 |
30 | neuron-neuron synaptic transmission (GO:0007270) | 3.97159077 |
31 | layer formation in cerebral cortex (GO:0021819) | 3.86419433 |
32 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 3.85819937 |
33 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.81041393 |
34 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.78050237 |
35 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.74881805 |
36 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 3.72777882 |
37 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.71223314 |
38 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 3.69488432 |
39 | regulation of synapse structural plasticity (GO:0051823) | 3.69091788 |
40 | neuron cell-cell adhesion (GO:0007158) | 3.68761017 |
41 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 3.59529054 |
42 | dendritic spine morphogenesis (GO:0060997) | 3.56479455 |
43 | cell communication by electrical coupling (GO:0010644) | 3.54656006 |
44 | transmission of nerve impulse (GO:0019226) | 3.50913696 |
45 | neuromuscular process controlling balance (GO:0050885) | 3.50904169 |
46 | regulation of postsynaptic membrane potential (GO:0060078) | 3.49266603 |
47 | positive regulation of membrane potential (GO:0045838) | 3.45926784 |
48 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 3.45239583 |
49 | proline transport (GO:0015824) | 3.42782405 |
50 | neuromuscular process controlling posture (GO:0050884) | 3.41685563 |
51 | regulation of synaptic plasticity (GO:0048167) | 3.40480016 |
52 | neurotransmitter transport (GO:0006836) | 3.39073832 |
53 | cell differentiation in hindbrain (GO:0021533) | 3.34898808 |
54 | potassium ion import (GO:0010107) | 3.32586878 |
55 | response to pheromone (GO:0019236) | 3.32219404 |
56 | activation of protein kinase A activity (GO:0034199) | 3.29893190 |
57 | negative regulation of dendrite morphogenesis (GO:0050774) | 3.29559984 |
58 | long-term synaptic potentiation (GO:0060291) | 3.23119419 |
59 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 3.22233078 |
60 | regulation of neurotransmitter secretion (GO:0046928) | 3.21795568 |
61 | membrane depolarization during action potential (GO:0086010) | 3.21147969 |
62 | regulation of dendritic spine morphogenesis (GO:0061001) | 3.18921507 |
63 | synaptic vesicle endocytosis (GO:0048488) | 3.16141510 |
64 | innervation (GO:0060384) | 3.13496183 |
65 | regulation of neurotransmitter levels (GO:0001505) | 3.13284279 |
66 | long term synaptic depression (GO:0060292) | 3.12732335 |
67 | establishment of nucleus localization (GO:0040023) | 3.12409007 |
68 | neuron recognition (GO:0008038) | 3.12029832 |
69 | regulation of synapse maturation (GO:0090128) | 3.11975935 |
70 | cellular sodium ion homeostasis (GO:0006883) | 3.11958875 |
71 | membrane depolarization (GO:0051899) | 3.11765774 |
72 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 3.07464827 |
73 | * dendrite morphogenesis (GO:0048813) | 3.06751947 |
74 | axonal fasciculation (GO:0007413) | 3.04875126 |
75 | glycine transport (GO:0015816) | 3.02784528 |
76 | L-amino acid import (GO:0043092) | 2.99134717 |
77 | presynaptic membrane assembly (GO:0097105) | 2.96489559 |
78 | regulation of vesicle fusion (GO:0031338) | 2.96011566 |
79 | negative regulation of hormone biosynthetic process (GO:0032353) | 2.95408195 |
80 | neuromuscular process (GO:0050905) | 2.93974170 |
81 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 2.93670010 |
82 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 2.92660493 |
83 | behavioral fear response (GO:0001662) | 2.91796008 |
84 | behavioral defense response (GO:0002209) | 2.91796008 |
85 | regulation of neurotransmitter transport (GO:0051588) | 2.91512770 |
86 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 2.91343757 |
87 | positive regulation of potassium ion transmembrane transport (GO:1901381) | 2.91221616 |
88 | dendritic spine organization (GO:0097061) | 2.89764871 |
89 | potassium ion homeostasis (GO:0055075) | 2.89073530 |
90 | positive regulation of synaptic transmission, glutamatergic (GO:0051968) | 2.87313554 |
91 | regulation of synaptic transmission (GO:0050804) | 2.85411814 |
92 | auditory behavior (GO:0031223) | 2.85376448 |
93 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 2.84815647 |
94 | synaptic transmission (GO:0007268) | 2.84270300 |
95 | presynaptic membrane organization (GO:0097090) | 2.84017317 |
96 | postsynaptic membrane organization (GO:0001941) | 2.83906612 |
97 | membrane hyperpolarization (GO:0060081) | 2.83413863 |
98 | membrane repolarization (GO:0086009) | 2.82561801 |
99 | adult walking behavior (GO:0007628) | 2.82060788 |
100 | fear response (GO:0042596) | 2.81052134 |
101 | neuronal ion channel clustering (GO:0045161) | 2.80772142 |
102 | regulation of voltage-gated calcium channel activity (GO:1901385) | 2.80489598 |
103 | synapse assembly (GO:0007416) | 2.78657952 |
104 | central nervous system myelination (GO:0022010) | 2.77809976 |
105 | axon ensheathment in central nervous system (GO:0032291) | 2.77809976 |
106 | chemosensory behavior (GO:0007635) | 2.77705551 |
107 | learning (GO:0007612) | 2.76025710 |
108 | apical protein localization (GO:0045176) | 2.66493780 |
109 | negative regulation of hormone metabolic process (GO:0032351) | 2.61787202 |
110 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 2.61222030 |
111 | cell communication involved in cardiac conduction (GO:0086065) | 2.59842954 |
112 | mating behavior (GO:0007617) | 2.54886989 |
113 | amino acid import (GO:0043090) | 2.50580453 |
114 | positive regulation of dendritic spine development (GO:0060999) | 2.48062889 |
115 | detection of calcium ion (GO:0005513) | 2.46711368 |
116 | paraxial mesoderm development (GO:0048339) | 2.46227098 |
117 | cAMP-mediated signaling (GO:0019933) | 2.40923263 |
118 | cerebellar Purkinje cell layer development (GO:0021680) | 2.40857648 |
119 | negative regulation of dendrite development (GO:2000171) | 2.40602868 |
120 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 2.36029443 |
121 | regulation of cell communication by electrical coupling (GO:0010649) | 2.35810795 |
122 | embryonic retina morphogenesis in camera-type eye (GO:0060059) | 2.26627850 |
123 | notochord development (GO:0030903) | 2.26618020 |
124 | cochlea development (GO:0090102) | 2.24734880 |
125 | atrial cardiac muscle cell action potential (GO:0086014) | 2.18068563 |
126 | mechanosensory behavior (GO:0007638) | 2.18032067 |
127 | positive regulation of dendrite development (GO:1900006) | 2.17429338 |
128 | positive regulation of vascular permeability (GO:0043117) | 2.15872188 |
129 | asymmetric protein localization (GO:0008105) | 2.15446444 |
130 | regulation of dendritic spine development (GO:0060998) | 2.14171720 |
131 | regulation of steroid hormone biosynthetic process (GO:0090030) | 2.13889654 |
132 | righting reflex (GO:0060013) | 2.13871203 |
133 | clathrin coat assembly (GO:0048268) | 2.11248124 |
134 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 2.10645116 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.53495910 |
2 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 3.27827694 |
3 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 3.09424383 |
4 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 3.00873903 |
5 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.98124678 |
6 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.90296824 |
7 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.90296824 |
8 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.69429527 |
9 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.62074908 |
10 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.61510106 |
11 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.59837394 |
12 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.57636990 |
13 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.56986590 |
14 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.46995379 |
15 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.42585334 |
16 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.40188069 |
17 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.40185348 |
18 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.30473397 |
19 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.27959838 |
20 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.23747739 |
21 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.21624663 |
22 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.19202432 |
23 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.13246970 |
24 | * REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.94014751 |
25 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.93317409 |
26 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.86830716 |
27 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.86514134 |
28 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.84772228 |
29 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.81767323 |
30 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.72782738 |
31 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.67577150 |
32 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.62951664 |
33 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.61436634 |
34 | * SMAD4_21799915_ChIP-Seq_A2780_Human | 1.57408655 |
35 | FUS_26573619_Chip-Seq_HEK293_Human | 1.55016333 |
36 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.50463586 |
37 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.50254362 |
38 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.49065430 |
39 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.44953342 |
40 | * CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.44398139 |
41 | * POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.42422909 |
42 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.38619811 |
43 | * SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.38554059 |
44 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.35349830 |
45 | * CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.33941030 |
46 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.33181802 |
47 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.32209591 |
48 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.29915021 |
49 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.28776118 |
50 | * MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.27658076 |
51 | * SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.26948827 |
52 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.25769621 |
53 | AR_19668381_ChIP-Seq_PC3_Human | 1.25359611 |
54 | * NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.25047721 |
55 | * SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.24876896 |
56 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.24555342 |
57 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.23625572 |
58 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.20055403 |
59 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.19677891 |
60 | KDM2B_26808549_Chip-Seq_K562_Human | 1.19462058 |
61 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.19444889 |
62 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.19328684 |
63 | * AR_25329375_ChIP-Seq_VCAP_Human | 1.18682486 |
64 | STAT3_23295773_ChIP-Seq_U87_Human | 1.18387254 |
65 | * P300_19829295_ChIP-Seq_ESCs_Human | 1.17904449 |
66 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.17858460 |
67 | * SOX9_26525672_Chip-Seq_HEART_Mouse | 1.17277828 |
68 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 1.16646815 |
69 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.16515453 |
70 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.16343019 |
71 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.15694896 |
72 | * RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.15476507 |
73 | * SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.15257071 |
74 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.14897630 |
75 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.13361814 |
76 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.13097085 |
77 | * ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.11759268 |
78 | * SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.11657303 |
79 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.10613951 |
80 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.10363729 |
81 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.10058063 |
82 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.09149049 |
83 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.08943536 |
84 | * ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.08822362 |
85 | * TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.07841504 |
86 | TP53_16413492_ChIP-PET_HCT116_Human | 1.07246031 |
87 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.06213119 |
88 | * TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.05933619 |
89 | TBX3_20139965_ChIP-Seq_MESCs_Mouse | 1.05564667 |
90 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.05490569 |
91 | * TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.04620066 |
92 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.03618844 |
93 | TBX3_20139965_ChIP-Seq_ESCs_Mouse | 1.02904222 |
94 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.02095214 |
95 | * TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.01682067 |
96 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.01625223 |
97 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.01479017 |
98 | * LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.01390560 |
99 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.00988132 |
100 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.00138576 |
101 | TCF4_23295773_ChIP-Seq_U87_Human | 0.99657200 |
102 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.99096844 |
103 | AR_21909140_ChIP-Seq_LNCAP_Human | 0.99003938 |
104 | * NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.97479238 |
105 | * AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.97375404 |
106 | POU5F1_18347094_ChIP-ChIP_MESCs_Mouse | 0.97164317 |
107 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 0.96857839 |
108 | RXR_22108803_ChIP-Seq_LS180_Human | 0.96108330 |
109 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.95989198 |
110 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.95464073 |
111 | * SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.95266860 |
112 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.95229878 |
113 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 0.94121081 |
114 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 0.93248936 |
115 | * SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.92546968 |
116 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.91319120 |
117 | * RUNX2_22187159_ChIP-Seq_PCA_Human | 0.90771737 |
118 | * SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.90720735 |
119 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.90704167 |
120 | TP53_18474530_ChIP-ChIP_U2OS_Human | 0.88548599 |
121 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.87256923 |
122 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.87228701 |
123 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.86540746 |
124 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.86312871 |
125 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 0.85603736 |
126 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.85171038 |
127 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 0.84930670 |
128 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.83482725 |
129 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.83319337 |
130 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.83119025 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 6.75162201 |
2 | MP0003880_abnormal_central_pattern | 4.36748444 |
3 | MP0003635_abnormal_synaptic_transmissio | 4.11924955 |
4 | MP0009046_muscle_twitch | 3.59398217 |
5 | MP0004270_analgesia | 3.56542525 |
6 | MP0009745_abnormal_behavioral_response | 3.28167035 |
7 | MP0002064_seizures | 3.13342631 |
8 | MP0002063_abnormal_learning/memory/cond | 3.12403583 |
9 | MP0001968_abnormal_touch/_nociception | 2.84571214 |
10 | MP0002272_abnormal_nervous_system | 2.78557170 |
11 | MP0002572_abnormal_emotion/affect_behav | 2.61214937 |
12 | MP0002734_abnormal_mechanical_nocicepti | 2.59015306 |
13 | MP0008569_lethality_at_weaning | 2.53789355 |
14 | MP0005423_abnormal_somatic_nervous | 2.49769676 |
15 | MP0002735_abnormal_chemical_nociception | 2.44246277 |
16 | MP0001486_abnormal_startle_reflex | 2.31324277 |
17 | MP0003123_paternal_imprinting | 2.24856968 |
18 | MP0001440_abnormal_grooming_behavior | 2.22177528 |
19 | MP0009780_abnormal_chondrocyte_physiolo | 2.20566564 |
20 | MP0002736_abnormal_nociception_after | 2.20188565 |
21 | MP0002067_abnormal_sensory_capabilities | 2.13072734 |
22 | MP0001501_abnormal_sleep_pattern | 2.12631776 |
23 | MP0002184_abnormal_innervation | 2.00442857 |
24 | MP0004858_abnormal_nervous_system | 1.95164665 |
25 | MP0002733_abnormal_thermal_nociception | 1.90208064 |
26 | MP0003329_amyloid_beta_deposits | 1.83722974 |
27 | MP0001970_abnormal_pain_threshold | 1.83137262 |
28 | MP0004145_abnormal_muscle_electrophysio | 1.77329373 |
29 | MP0004885_abnormal_endolymph | 1.70096310 |
30 | MP0000778_abnormal_nervous_system | 1.68825274 |
31 | MP0004811_abnormal_neuron_physiology | 1.62040085 |
32 | MP0000955_abnormal_spinal_cord | 1.61432941 |
33 | MP0002557_abnormal_social/conspecific_i | 1.59041882 |
34 | MP0003121_genomic_imprinting | 1.51086151 |
35 | MP0004924_abnormal_behavior | 1.50821935 |
36 | MP0005386_behavior/neurological_phenoty | 1.50821935 |
37 | MP0002909_abnormal_adrenal_gland | 1.50155342 |
38 | MP0002066_abnormal_motor_capabilities/c | 1.41432434 |
39 | MP0003633_abnormal_nervous_system | 1.39506529 |
40 | MP0002882_abnormal_neuron_morphology | 1.38834332 |
41 | MP0006276_abnormal_autonomic_nervous | 1.33521919 |
42 | MP0003890_abnormal_embryonic-extraembry | 1.31280388 |
43 | MP0003879_abnormal_hair_cell | 1.31144412 |
44 | MP0000566_synostosis | 1.29983324 |
45 | MP0004142_abnormal_muscle_tone | 1.28161599 |
46 | MP0003631_nervous_system_phenotype | 1.26204775 |
47 | MP0000751_myopathy | 1.23842408 |
48 | MP0005623_abnormal_meninges_morphology | 1.21714829 |
49 | MP0003122_maternal_imprinting | 1.19740810 |
50 | MP0003632_abnormal_nervous_system | 1.19623416 |
51 | MP0002938_white_spotting | 1.18623480 |
52 | MP0003787_abnormal_imprinting | 1.16203242 |
53 | MP0000013_abnormal_adipose_tissue | 1.15845316 |
54 | MP0008877_abnormal_DNA_methylation | 1.13354973 |
55 | MP0001984_abnormal_olfaction | 1.09652534 |
56 | MP0002152_abnormal_brain_morphology | 1.09044303 |
57 | MP0000579_abnormal_nail_morphology | 1.08562437 |
58 | MP0005646_abnormal_pituitary_gland | 1.07648732 |
59 | MP0001502_abnormal_circadian_rhythm | 1.07351729 |
60 | MP0005171_absent_coat_pigmentation | 1.06841705 |
61 | MP0003690_abnormal_glial_cell | 1.06780234 |
62 | MP0000920_abnormal_myelination | 1.06335245 |
63 | MP0000462_abnormal_digestive_system | 1.03676267 |
64 | MP0004215_abnormal_myocardial_fiber | 1.02825731 |
65 | MP0004742_abnormal_vestibular_system | 1.02771706 |
66 | MP0010030_abnormal_orbit_morphology | 1.02216445 |
67 | MP0002822_catalepsy | 1.00558533 |
68 | MP0003937_abnormal_limbs/digits/tail_de | 0.98666607 |
69 | MP0002233_abnormal_nose_morphology | 0.97192323 |
70 | MP0003283_abnormal_digestive_organ | 0.96979413 |
71 | MP0004133_heterotaxia | 0.95216002 |
72 | MP0009672_abnormal_birth_weight | 0.95053396 |
73 | MP0001299_abnormal_eye_distance/ | 0.94634354 |
74 | MP0002160_abnormal_reproductive_system | 0.93982652 |
75 | MP0003385_abnormal_body_wall | 0.93918702 |
76 | MP0003119_abnormal_digestive_system | 0.93490695 |
77 | MP0004484_altered_response_of | 0.91999134 |
78 | MP0003634_abnormal_glial_cell | 0.91009229 |
79 | MP0004085_abnormal_heartbeat | 0.89898261 |
80 | MP0001177_atelectasis | 0.87988038 |
81 | MP0003136_yellow_coat_color | 0.86318307 |
82 | MP0000631_abnormal_neuroendocrine_gland | 0.85625141 |
83 | MP0002090_abnormal_vision | 0.85523107 |
84 | MP0002229_neurodegeneration | 0.84678924 |
85 | MP0003941_abnormal_skin_development | 0.84346738 |
86 | MP0000003_abnormal_adipose_tissue | 0.83995616 |
87 | MP0005645_abnormal_hypothalamus_physiol | 0.82567759 |
88 | MP0005167_abnormal_blood-brain_barrier | 0.81199312 |
89 | MP0000428_abnormal_craniofacial_morphol | 0.81094263 |
90 | MP0001485_abnormal_pinna_reflex | 0.80712645 |
91 | MP0001963_abnormal_hearing_physiology | 0.79612968 |
92 | MP0010234_abnormal_vibrissa_follicle | 0.79297956 |
93 | MP0000604_amyloidosis | 0.78701681 |
94 | MP0003942_abnormal_urinary_system | 0.78266563 |
95 | MP0003137_abnormal_impulse_conducting | 0.78066365 |
96 | MP0010678_abnormal_skin_adnexa | 0.77939427 |
97 | MP0002069_abnormal_eating/drinking_beha | 0.77849006 |
98 | MP0004147_increased_porphyrin_level | 0.77623656 |
99 | MP0005409_darkened_coat_color | 0.77559019 |
100 | MP0002638_abnormal_pupillary_reflex | 0.77178359 |
101 | MP0000537_abnormal_urethra_morphology | 0.77149772 |
102 | MP0001346_abnormal_lacrimal_gland | 0.76796828 |
103 | MP0001529_abnormal_vocalization | 0.76522144 |
104 | MP0002697_abnormal_eye_size | 0.76374226 |
105 | MP0002837_dystrophic_cardiac_calcinosis | 0.76048102 |
106 | MP0009703_decreased_birth_body | 0.75570971 |
107 | MP0000639_abnormal_adrenal_gland | 0.74957105 |
108 | MP0008872_abnormal_physiological_respon | 0.74233920 |
109 | MP0001188_hyperpigmentation | 0.74039145 |
110 | MP0008874_decreased_physiological_sensi | 0.73871125 |
111 | MP0004233_abnormal_muscle_weight | 0.72552096 |
112 | MP0001944_abnormal_pancreas_morphology | 0.72342079 |
113 | MP0003938_abnormal_ear_development | 0.71662144 |
114 | MP0001293_anophthalmia | 0.71254138 |
115 | MP0001905_abnormal_dopamine_level | 0.70782661 |
116 | MP0003075_altered_response_to | 0.70218953 |
117 | MP0002752_abnormal_somatic_nervous | 0.69909709 |
118 | MP0004043_abnormal_pH_regulation | 0.68254303 |
119 | MP0010386_abnormal_urinary_bladder | 0.66353953 |
120 | MP0002089_abnormal_postnatal_growth/wei | 0.65257741 |
121 | MP0000569_abnormal_digit_pigmentation | 0.65036248 |
122 | MP0005187_abnormal_penis_morphology | 0.64681918 |
123 | MP0003045_fibrosis | 0.62149250 |
124 | MP0005551_abnormal_eye_electrophysiolog | 0.61375876 |
125 | MP0000747_muscle_weakness | 0.58529286 |
126 | MP0001943_abnormal_respiration | 0.57625256 |
127 | MP0010769_abnormal_survival | 0.57490187 |
128 | MP0003861_abnormal_nervous_system | 0.56814445 |
129 | MP0001664_abnormal_digestion | 0.56394933 |
130 | MP0005394_taste/olfaction_phenotype | 0.55974710 |
131 | MP0005499_abnormal_olfactory_system | 0.55974710 |
132 | MP0008961_abnormal_basal_metabolism | 0.54845973 |
133 | MP0004510_myositis | 0.54834252 |
134 | MP0010770_preweaning_lethality | 0.53380766 |
135 | MP0002082_postnatal_lethality | 0.53380766 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Focal motor seizures (HP:0011153) | 7.36168955 |
2 | Myokymia (HP:0002411) | 6.28931293 |
3 | Action tremor (HP:0002345) | 5.61897848 |
4 | Focal seizures (HP:0007359) | 5.48132702 |
5 | Progressive cerebellar ataxia (HP:0002073) | 5.24355008 |
6 | Visual hallucinations (HP:0002367) | 5.18293976 |
7 | Atonic seizures (HP:0010819) | 5.17232633 |
8 | Febrile seizures (HP:0002373) | 4.42647919 |
9 | Epileptic encephalopathy (HP:0200134) | 4.42316512 |
10 | Gaze-evoked nystagmus (HP:0000640) | 4.08355305 |
11 | Absence seizures (HP:0002121) | 4.07618946 |
12 | Dysdiadochokinesis (HP:0002075) | 3.73579293 |
13 | Dialeptic seizures (HP:0011146) | 3.69042959 |
14 | Scanning speech (HP:0002168) | 3.58956119 |
15 | Broad-based gait (HP:0002136) | 3.55640825 |
16 | Generalized tonic-clonic seizures (HP:0002069) | 3.47696093 |
17 | Dysmetria (HP:0001310) | 3.42864975 |
18 | Hemiplegia (HP:0002301) | 3.37291314 |
19 | Abnormality of the lower motor neuron (HP:0002366) | 3.27670497 |
20 | Intention tremor (HP:0002080) | 3.22397340 |
21 | Truncal ataxia (HP:0002078) | 3.22046487 |
22 | Genetic anticipation (HP:0003743) | 3.17232299 |
23 | Dysmetric saccades (HP:0000641) | 3.10162901 |
24 | Impaired smooth pursuit (HP:0007772) | 3.08982521 |
25 | Supranuclear gaze palsy (HP:0000605) | 2.99687444 |
26 | Depression (HP:0000716) | 2.95572604 |
27 | Hyperinsulinemic hypoglycemia (HP:0000825) | 2.95455672 |
28 | Hypoglycemic seizures (HP:0002173) | 2.88603434 |
29 | Ventricular fibrillation (HP:0001663) | 2.81213693 |
30 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.81011939 |
31 | Abnormality of ocular smooth pursuit (HP:0000617) | 2.79951000 |
32 | Poor eye contact (HP:0000817) | 2.78937182 |
33 | Hemiparesis (HP:0001269) | 2.78911706 |
34 | Abnormal eating behavior (HP:0100738) | 2.72572775 |
35 | Ankle clonus (HP:0011448) | 2.72478937 |
36 | Annular pancreas (HP:0001734) | 2.69112500 |
37 | Abnormality of binocular vision (HP:0011514) | 2.68614999 |
38 | Diplopia (HP:0000651) | 2.68614999 |
39 | Anxiety (HP:0000739) | 2.68108762 |
40 | Abnormal social behavior (HP:0012433) | 2.60068139 |
41 | Impaired social interactions (HP:0000735) | 2.60068139 |
42 | Megalencephaly (HP:0001355) | 2.51940985 |
43 | Hyperventilation (HP:0002883) | 2.48858036 |
44 | Postural instability (HP:0002172) | 2.46989211 |
45 | Amblyopia (HP:0000646) | 2.45340775 |
46 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.41664101 |
47 | Postural tremor (HP:0002174) | 2.32961701 |
48 | Abnormality of the corticospinal tract (HP:0002492) | 2.29564486 |
49 | Spastic gait (HP:0002064) | 2.29134852 |
50 | Drooling (HP:0002307) | 2.28058319 |
51 | Excessive salivation (HP:0003781) | 2.28058319 |
52 | Mutism (HP:0002300) | 2.27214849 |
53 | Stereotypic behavior (HP:0000733) | 2.26261228 |
54 | Status epilepticus (HP:0002133) | 2.23950669 |
55 | Insidious onset (HP:0003587) | 2.23327791 |
56 | Termporal pattern (HP:0011008) | 2.23327791 |
57 | Lower limb asymmetry (HP:0100559) | 2.20223237 |
58 | Urinary urgency (HP:0000012) | 2.19904282 |
59 | Increased circulating renin level (HP:0000848) | 2.16406921 |
60 | Pheochromocytoma (HP:0002666) | 2.13246972 |
61 | Bundle branch block (HP:0011710) | 2.10701800 |
62 | Neurofibrillary tangles (HP:0002185) | 2.10276334 |
63 | Aplasia of the phalanges of the hand (HP:0009802) | 2.09338376 |
64 | Aplasia involving bones of the extremities (HP:0009825) | 2.09338376 |
65 | Aplasia involving bones of the upper limbs (HP:0009823) | 2.09338376 |
66 | Gait ataxia (HP:0002066) | 2.08645953 |
67 | Cutaneous finger syndactyly (HP:0010554) | 2.07860839 |
68 | Macroorchidism (HP:0000053) | 2.06849179 |
69 | Abnormality of saccadic eye movements (HP:0000570) | 2.05850673 |
70 | Fetal akinesia sequence (HP:0001989) | 2.04496075 |
71 | Agitation (HP:0000713) | 2.04289407 |
72 | Cerebral inclusion bodies (HP:0100314) | 2.02171561 |
73 | Pointed chin (HP:0000307) | 2.01935469 |
74 | Epileptiform EEG discharges (HP:0011182) | 2.01290047 |
75 | Papilledema (HP:0001085) | 1.98832295 |
76 | Myotonia (HP:0002486) | 1.96831877 |
77 | Hypoglycemic coma (HP:0001325) | 1.96048618 |
78 | Torticollis (HP:0000473) | 1.95830651 |
79 | Tetraplegia (HP:0002445) | 1.95485798 |
80 | Incomplete penetrance (HP:0003829) | 1.94639237 |
81 | Limb dystonia (HP:0002451) | 1.94049791 |
82 | Enlarged penis (HP:0000040) | 1.93191191 |
83 | Impaired vibratory sensation (HP:0002495) | 1.92169597 |
84 | Bradykinesia (HP:0002067) | 1.90983093 |
85 | Horizontal nystagmus (HP:0000666) | 1.90203997 |
86 | EEG with generalized epileptiform discharges (HP:0011198) | 1.89488228 |
87 | Papillary thyroid carcinoma (HP:0002895) | 1.88707864 |
88 | Focal dystonia (HP:0004373) | 1.87452355 |
89 | Cutaneous syndactyly (HP:0012725) | 1.87272775 |
90 | Absent speech (HP:0001344) | 1.85491005 |
91 | Amyotrophic lateral sclerosis (HP:0007354) | 1.84717150 |
92 | Progressive inability to walk (HP:0002505) | 1.81822581 |
93 | Lower limb muscle weakness (HP:0007340) | 1.81315098 |
94 | Hypsarrhythmia (HP:0002521) | 1.81267410 |
95 | Spinal canal stenosis (HP:0003416) | 1.79289876 |
96 | Decreased number of large peripheral myelinated nerve fibers (HP:0003387) | 1.77566382 |
97 | Limb ataxia (HP:0002070) | 1.77526981 |
98 | Menstrual irregularities (HP:0000858) | 1.77525215 |
99 | Obstructive sleep apnea (HP:0002870) | 1.76997813 |
100 | Sleep apnea (HP:0010535) | 1.76625488 |
101 | Generalized myoclonic seizures (HP:0002123) | 1.76425227 |
102 | Slow progression (HP:0003677) | 1.74727483 |
103 | Hypoventilation (HP:0002791) | 1.74673486 |
104 | Neuroendocrine neoplasm (HP:0100634) | 1.74128115 |
105 | Hepatoblastoma (HP:0002884) | 1.73108358 |
106 | Alacrima (HP:0000522) | 1.72776944 |
107 | Neuronal loss in central nervous system (HP:0002529) | 1.71576900 |
108 | Neoplasm of the heart (HP:0100544) | 1.70471924 |
109 | Insomnia (HP:0100785) | 1.68733415 |
110 | Turricephaly (HP:0000262) | 1.68184424 |
111 | Aqueductal stenosis (HP:0002410) | 1.67878739 |
112 | Rapidly progressive (HP:0003678) | 1.67564078 |
113 | Akinesia (HP:0002304) | 1.66030685 |
114 | Blue irides (HP:0000635) | 1.64907660 |
115 | Psychosis (HP:0000709) | 1.64327211 |
116 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 1.64122804 |
117 | Gait imbalance (HP:0002141) | 1.63859511 |
118 | Bronchomalacia (HP:0002780) | 1.62880904 |
119 | Clonus (HP:0002169) | 1.61929077 |
120 | Heterochromia iridis (HP:0001100) | 1.61193506 |
121 | Cerebral hypomyelination (HP:0006808) | 1.60572052 |
122 | Volvulus (HP:0002580) | 1.59712680 |
123 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 1.57229153 |
124 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 1.57229153 |
125 | Decreased lacrimation (HP:0000633) | 1.53090690 |
126 | Hyperglycemia (HP:0003074) | 1.52363907 |
127 | Impaired pain sensation (HP:0007328) | 1.51969204 |
128 | Abnormality of pain sensation (HP:0010832) | 1.51969204 |
129 | Increased nuchal translucency (HP:0010880) | 1.48901203 |
130 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.47646719 |
131 | Symptomatic seizures (HP:0011145) | 1.46490713 |
132 | Vertebral clefting (HP:0008428) | 1.45760296 |
133 | Rhinitis (HP:0012384) | 1.45560263 |
134 | Insulin-resistant diabetes mellitus (HP:0000831) | 1.45031422 |
135 | Abnormality of the ischium (HP:0003174) | 1.40578904 |
136 | Vaginal atresia (HP:0000148) | 1.39169024 |
137 | Abnormality of the astrocytes (HP:0100707) | 1.38766805 |
138 | Astrocytoma (HP:0009592) | 1.38766805 |
139 | Genital tract atresia (HP:0001827) | 1.38209110 |
140 | Urethral obstruction (HP:0000796) | 1.36056248 |
141 | Short chin (HP:0000331) | 1.35737603 |
142 | Overriding aorta (HP:0002623) | 1.35176955 |
Rank | Gene Set | Z-score |
---|---|---|
1 | NTRK3 | 4.75079790 |
2 | MAP3K9 | 3.66888853 |
3 | EPHA4 | 3.17224482 |
4 | MAP3K4 | 2.83245064 |
5 | MINK1 | 2.68158492 |
6 | DAPK2 | 2.32729094 |
7 | MAP2K7 | 2.22235812 |
8 | PAK6 | 2.21169188 |
9 | MARK1 | 2.18101831 |
10 | KSR2 | 2.11137834 |
11 | CAMKK1 | 2.07332499 |
12 | CAMKK2 | 2.02896902 |
13 | MAP2K4 | 1.99779084 |
14 | NTRK2 | 1.98053517 |
15 | TIE1 | 1.90120587 |
16 | PRKD3 | 1.89964990 |
17 | PDK2 | 1.72873201 |
18 | NTRK1 | 1.69810339 |
19 | STK38 | 1.66594963 |
20 | PRPF4B | 1.65885289 |
21 | CASK | 1.65117056 |
22 | TNIK | 1.56315431 |
23 | MKNK1 | 1.56067488 |
24 | CDK19 | 1.55459978 |
25 | RIPK1 | 1.51324366 |
26 | KSR1 | 1.49941631 |
27 | PLK2 | 1.45310386 |
28 | CDK5 | 1.44978228 |
29 | GRK5 | 1.40240715 |
30 | MAP3K2 | 1.31962881 |
31 | TYRO3 | 1.31511510 |
32 | MAP3K12 | 1.30538940 |
33 | STK38L | 1.27948824 |
34 | PRKCG | 1.26610308 |
35 | WNK1 | 1.26282015 |
36 | LATS1 | 1.23091607 |
37 | DAPK1 | 1.21481961 |
38 | MKNK2 | 1.19286075 |
39 | MAPK13 | 1.19190048 |
40 | UHMK1 | 1.16180849 |
41 | RIPK4 | 1.14422907 |
42 | SGK223 | 1.13413956 |
43 | SGK494 | 1.13413956 |
44 | LMTK2 | 1.13187999 |
45 | PBK | 1.11104436 |
46 | ARAF | 1.09724801 |
47 | TRPM7 | 1.07668716 |
48 | OXSR1 | 1.07165619 |
49 | FER | 1.06748812 |
50 | MET | 1.06471781 |
51 | CAMK1 | 1.04695837 |
52 | PHKG2 | 1.04089675 |
53 | PHKG1 | 1.04089675 |
54 | PTK2B | 1.01987409 |
55 | CAMK2B | 1.00441246 |
56 | CSNK1G1 | 0.98909672 |
57 | PRKCH | 0.98844069 |
58 | CAMK2A | 0.98808349 |
59 | RET | 0.96980886 |
60 | LATS2 | 0.96576767 |
61 | SGK2 | 0.96201070 |
62 | PNCK | 0.95263753 |
63 | BRSK1 | 0.92311715 |
64 | CDK18 | 0.92240881 |
65 | CDK15 | 0.91765709 |
66 | FES | 0.90334133 |
67 | CDK14 | 0.88491760 |
68 | FRK | 0.88366901 |
69 | MAP3K13 | 0.87529022 |
70 | SGK3 | 0.86898508 |
71 | TSSK6 | 0.86717883 |
72 | STK11 | 0.86543578 |
73 | EEF2K | 0.80164124 |
74 | PAK3 | 0.79763860 |
75 | CDK11A | 0.78308749 |
76 | CDC42BPA | 0.77443436 |
77 | BRD4 | 0.77295029 |
78 | SIK2 | 0.76372904 |
79 | ALK | 0.76078995 |
80 | TTK | 0.75326201 |
81 | CSNK1G3 | 0.70944698 |
82 | PDK1 | 0.70819458 |
83 | PLK3 | 0.69296508 |
84 | PDPK1 | 0.68656806 |
85 | DYRK1A | 0.68226915 |
86 | ROCK2 | 0.67447137 |
87 | DDR2 | 0.67174573 |
88 | CAMK4 | 0.66877313 |
89 | SGK1 | 0.66854035 |
90 | CAMK2G | 0.66475445 |
91 | PINK1 | 0.65630498 |
92 | CSNK1E | 0.64106050 |
93 | CAMK2D | 0.63489697 |
94 | MARK2 | 0.61719590 |
95 | BRSK2 | 0.61628690 |
96 | NEK6 | 0.61511527 |
97 | CSNK1A1L | 0.60556391 |
98 | STK3 | 0.60264527 |
99 | NEK1 | 0.60170459 |
100 | MAPK15 | 0.60083271 |
101 | DMPK | 0.59199252 |
102 | MAP3K7 | 0.58811347 |
103 | RPS6KB1 | 0.57202551 |
104 | MST1R | 0.56851518 |
105 | CDK3 | 0.56831862 |
106 | RAF1 | 0.55730559 |
107 | PRKCE | 0.55698893 |
108 | CSNK1G2 | 0.54843013 |
109 | MAP3K1 | 0.54821404 |
110 | BMPR1B | 0.52426587 |
111 | ERBB4 | 0.52362109 |
112 | ICK | 0.51391926 |
113 | RPS6KA3 | 0.51115122 |
114 | STK39 | 0.50032416 |
115 | AKT2 | 0.49998834 |
116 | CAMK1D | 0.49770411 |
117 | FGFR1 | 0.49736452 |
118 | PRKDC | 0.49078572 |
119 | FYN | 0.47824009 |
120 | FGFR2 | 0.47313167 |
121 | PDGFRA | 0.46644807 |
122 | ERBB3 | 0.46486921 |
123 | SCYL2 | 0.46292099 |
124 | CAMK1G | 0.46114373 |
125 | BCR | 0.46041197 |
126 | MAP2K1 | 0.44672909 |
127 | TAOK1 | 0.44369020 |
128 | PTK2 | 0.44306143 |
129 | MAPK10 | 0.42326978 |
130 | MAPK12 | 0.40786029 |
131 | LIMK1 | 0.40336135 |
132 | MAPKAPK5 | 0.40127068 |
133 | AKT3 | 0.38715384 |
134 | PRKCZ | 0.37601892 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nicotine addiction_Homo sapiens_hsa05033 | 3.76016724 |
2 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.92022604 |
3 | Long-term potentiation_Homo sapiens_hsa04720 | 2.79668027 |
4 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.67125080 |
5 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.66423877 |
6 | Circadian entrainment_Homo sapiens_hsa04713 | 2.65236124 |
7 | GABAergic synapse_Homo sapiens_hsa04727 | 2.55209133 |
8 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.23753377 |
9 | Morphine addiction_Homo sapiens_hsa05032 | 2.23602911 |
10 | Olfactory transduction_Homo sapiens_hsa04740 | 2.21303015 |
11 | Salivary secretion_Homo sapiens_hsa04970 | 2.17760846 |
12 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 2.16921172 |
13 | Gastric acid secretion_Homo sapiens_hsa04971 | 2.02170599 |
14 | Long-term depression_Homo sapiens_hsa04730 | 1.97838896 |
15 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.95267137 |
16 | Insulin secretion_Homo sapiens_hsa04911 | 1.91385099 |
17 | Taste transduction_Homo sapiens_hsa04742 | 1.90791772 |
18 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.87497668 |
19 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.74059278 |
20 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.66101570 |
21 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.63397109 |
22 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.60291881 |
23 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.57892760 |
24 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.56506481 |
25 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.56059326 |
26 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.53623518 |
27 | Renin secretion_Homo sapiens_hsa04924 | 1.47724048 |
28 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.47189271 |
29 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.44315415 |
30 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.38636900 |
31 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.31885737 |
32 | Gap junction_Homo sapiens_hsa04540 | 1.30936153 |
33 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.28021764 |
34 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.25608039 |
35 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.23523116 |
36 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.23443033 |
37 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.22200588 |
38 | Cocaine addiction_Homo sapiens_hsa05030 | 1.21998031 |
39 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.21837724 |
40 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.20935301 |
41 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.18659255 |
42 | Pancreatic secretion_Homo sapiens_hsa04972 | 1.16410827 |
43 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.15714450 |
44 | Axon guidance_Homo sapiens_hsa04360 | 1.12048851 |
45 | Melanogenesis_Homo sapiens_hsa04916 | 1.09366772 |
46 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.08715561 |
47 | Glioma_Homo sapiens_hsa05214 | 1.06346748 |
48 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 1.03877451 |
49 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.03089444 |
50 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.00990372 |
51 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.98713130 |
52 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.96913995 |
53 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.96527294 |
54 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.92683445 |
55 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.92032851 |
56 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.90557456 |
57 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.90032008 |
58 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.87980628 |
59 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.87364090 |
60 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.85672107 |
61 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.83355793 |
62 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.81273318 |
63 | Adherens junction_Homo sapiens_hsa04520 | 0.79832628 |
64 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.78011726 |
65 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.77244771 |
66 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.76132464 |
67 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.73071466 |
68 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.70147725 |
69 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.69598654 |
70 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.68762713 |
71 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.68741910 |
72 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.68277636 |
73 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.66984520 |
74 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.66877126 |
75 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.65554300 |
76 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.65492380 |
77 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.65316823 |
78 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.63418459 |
79 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.63321646 |
80 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.62951434 |
81 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.62571990 |
82 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.61774271 |
83 | Bile secretion_Homo sapiens_hsa04976 | 0.61046629 |
84 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.60794003 |
85 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.58660336 |
86 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.58044172 |
87 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.56607674 |
88 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.56204466 |
89 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.55419043 |
90 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.54803280 |
91 | Circadian rhythm_Homo sapiens_hsa04710 | 0.53741477 |
92 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.53332597 |
93 | Endocytosis_Homo sapiens_hsa04144 | 0.53218006 |
94 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.53199441 |
95 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.52884465 |
96 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.50829239 |
97 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.50626701 |
98 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.50330863 |
99 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.49575427 |
100 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.48530242 |
101 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.47671531 |
102 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.47351939 |
103 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.46960862 |
104 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.46450575 |
105 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.46165361 |
106 | Histidine metabolism_Homo sapiens_hsa00340 | 0.45596063 |
107 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.45000301 |
108 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.44697452 |
109 | Protein export_Homo sapiens_hsa03060 | 0.44298406 |
110 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.43201648 |
111 | Endometrial cancer_Homo sapiens_hsa05213 | 0.43140910 |
112 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.42281565 |
113 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.41597447 |
114 | Tight junction_Homo sapiens_hsa04530 | 0.41468233 |
115 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.39218596 |
116 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.39183086 |
117 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.36955470 |
118 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.35267918 |
119 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.35134524 |
120 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.31767566 |
121 | Prion diseases_Homo sapiens_hsa05020 | 0.31765131 |
122 | Phototransduction_Homo sapiens_hsa04744 | 0.31511398 |
123 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.30860092 |
124 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.29759783 |
125 | Focal adhesion_Homo sapiens_hsa04510 | 0.29251574 |
126 | Mineral absorption_Homo sapiens_hsa04978 | 0.28936509 |
127 | Alcoholism_Homo sapiens_hsa05034 | 0.28815153 |
128 | Platelet activation_Homo sapiens_hsa04611 | 0.28460034 |
129 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.27493775 |
130 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.27140178 |