

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | cell wall macromolecule catabolic process (GO:0016998) | 7.52794871 |
| 2 | cell wall macromolecule metabolic process (GO:0044036) | 7.35951382 |
| 3 | maturation of SSU-rRNA (GO:0030490) | 5.25944991 |
| 4 | labyrinthine layer development (GO:0060711) | 4.96050611 |
| 5 | ribosomal small subunit assembly (GO:0000028) | 4.92125388 |
| 6 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 4.88118357 |
| 7 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 4.55241244 |
| 8 | ATP synthesis coupled proton transport (GO:0015986) | 4.08582703 |
| 9 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.08582703 |
| 10 | positive regulation of digestive system process (GO:0060456) | 4.06299032 |
| 11 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.96919255 |
| 12 | piRNA metabolic process (GO:0034587) | 3.95490606 |
| 13 | DNA deamination (GO:0045006) | 3.94211316 |
| 14 | purine nucleotide salvage (GO:0032261) | 3.85661119 |
| 15 | cullin deneddylation (GO:0010388) | 3.76323262 |
| 16 | interferon-gamma production (GO:0032609) | 3.73798512 |
| 17 | regulation of skeletal muscle contraction (GO:0014819) | 3.71463434 |
| 18 | regulation of interleukin-8 biosynthetic process (GO:0045414) | 3.71247999 |
| 19 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.68927032 |
| 20 | response to nitric oxide (GO:0071731) | 3.58673187 |
| 21 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.56841814 |
| 22 | NADH dehydrogenase complex assembly (GO:0010257) | 3.56841814 |
| 23 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.56841814 |
| 24 | inner mitochondrial membrane organization (GO:0007007) | 3.54446276 |
| 25 | viral transcription (GO:0019083) | 3.48465702 |
| 26 | multicellular organismal aging (GO:0010259) | 3.47331358 |
| 27 | purine deoxyribonucleotide catabolic process (GO:0009155) | 3.44628589 |
| 28 | chaperone-mediated protein transport (GO:0072321) | 3.41615866 |
| 29 | nucleotide transmembrane transport (GO:1901679) | 3.36747645 |
| 30 | organic cation transport (GO:0015695) | 3.33856866 |
| 31 | ribosomal small subunit biogenesis (GO:0042274) | 3.30913838 |
| 32 | L-methionine salvage (GO:0071267) | 3.30198082 |
| 33 | L-methionine biosynthetic process (GO:0071265) | 3.30198082 |
| 34 | amino acid salvage (GO:0043102) | 3.30198082 |
| 35 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.24907961 |
| 36 | rRNA modification (GO:0000154) | 3.23309235 |
| 37 | toxin transport (GO:1901998) | 3.21977774 |
| 38 | negative regulation of interleukin-1 beta production (GO:0032691) | 3.17885835 |
| 39 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 3.17161002 |
| 40 | translational termination (GO:0006415) | 3.17121831 |
| 41 | deoxyribonucleotide catabolic process (GO:0009264) | 3.15688587 |
| 42 | protein complex biogenesis (GO:0070271) | 3.14013928 |
| 43 | AMP metabolic process (GO:0046033) | 3.11563152 |
| 44 | pseudouridine synthesis (GO:0001522) | 3.11438151 |
| 45 | ribosomal large subunit biogenesis (GO:0042273) | 3.10044374 |
| 46 | protein deneddylation (GO:0000338) | 3.09680068 |
| 47 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.07875049 |
| 48 | translation (GO:0006412) | 3.05258358 |
| 49 | positive regulation of prostaglandin secretion (GO:0032308) | 3.05178360 |
| 50 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.04500000 |
| 51 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 3.03314012 |
| 52 | autophagic vacuole fusion (GO:0000046) | 3.03273352 |
| 53 | GTP biosynthetic process (GO:0006183) | 3.01130347 |
| 54 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.99608181 |
| 55 | deoxyribose phosphate catabolic process (GO:0046386) | 2.98675014 |
| 56 | 4-hydroxyproline metabolic process (GO:0019471) | 2.98168862 |
| 57 | cotranslational protein targeting to membrane (GO:0006613) | 2.97110610 |
| 58 | rRNA metabolic process (GO:0016072) | 2.96952039 |
| 59 | translational elongation (GO:0006414) | 2.96819226 |
| 60 | rRNA processing (GO:0006364) | 2.96493571 |
| 61 | protein targeting to ER (GO:0045047) | 2.94630716 |
| 62 | nucleotide salvage (GO:0043173) | 2.92387126 |
| 63 | DNA methylation involved in gamete generation (GO:0043046) | 2.92084104 |
| 64 | protein neddylation (GO:0045116) | 2.89371551 |
| 65 | spliceosomal snRNP assembly (GO:0000387) | 2.89294098 |
| 66 | negative regulation of interleukin-1 production (GO:0032692) | 2.83602716 |
| 67 | positive regulation of syncytium formation by plasma membrane fusion (GO:0060143) | 2.82084815 |
| 68 | negative regulation of interleukin-8 production (GO:0032717) | 2.81985325 |
| 69 | UTP biosynthetic process (GO:0006228) | 2.81596829 |
| 70 | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:0000288) | 2.80739894 |
| 71 | carnitine transmembrane transport (GO:1902603) | 2.78797919 |
| 72 | negative regulation of muscle hypertrophy (GO:0014741) | 2.77841240 |
| 73 | grooming behavior (GO:0007625) | 2.74479633 |
| 74 | protein localization to endoplasmic reticulum (GO:0070972) | 2.74103055 |
| 75 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 2.73703028 |
| 76 | G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:0007199 | 2.72873214 |
| 77 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.67883762 |
| 78 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.67548012 |
| 79 | translational initiation (GO:0006413) | 2.66851779 |
| 80 | positive regulation of T cell chemotaxis (GO:0010820) | 2.66693356 |
| 81 | regulation of T cell chemotaxis (GO:0010819) | 2.66693356 |
| 82 | positive regulation of monocyte chemotaxis (GO:0090026) | 2.66120383 |
| 83 | somite development (GO:0061053) | 2.65228284 |
| 84 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.64227614 |
| 85 | protoporphyrinogen IX metabolic process (GO:0046501) | 2.64204185 |
| 86 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.62147274 |
| 87 | regulation of prostaglandin secretion (GO:0032306) | 2.61790792 |
| 88 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.60680365 |
| 89 | adaptation of signaling pathway (GO:0023058) | 2.60196100 |
| 90 | cellular component biogenesis (GO:0044085) | 2.58096286 |
| 91 | positive regulation of icosanoid secretion (GO:0032305) | 2.57222820 |
| 92 | protein-cofactor linkage (GO:0018065) | 2.55544693 |
| 93 | rRNA methylation (GO:0031167) | 2.55442731 |
| 94 | behavioral response to nicotine (GO:0035095) | 2.54269105 |
| 95 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.52233836 |
| 96 | heart trabecula formation (GO:0060347) | 2.51998598 |
| 97 | cellular response to exogenous dsRNA (GO:0071360) | 2.51691817 |
| 98 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.50132595 |
| 99 | termination of RNA polymerase III transcription (GO:0006386) | 2.50132595 |
| 100 | 2-deoxyribonucleotide metabolic process (GO:0009394) | 2.50031720 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 5.86000414 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.18443389 |
| 3 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.83012836 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.72800964 |
| 5 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.67586979 |
| 6 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.65592218 |
| 7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.56966587 |
| 8 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.97152648 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.96550461 |
| 10 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.76584826 |
| 11 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 2.74395166 |
| 12 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.67008939 |
| 13 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.47655971 |
| 14 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.41642210 |
| 15 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.37530559 |
| 16 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.33968913 |
| 17 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.32270223 |
| 18 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.28470396 |
| 19 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.27117160 |
| 20 | VDR_22108803_ChIP-Seq_LS180_Human | 2.25296475 |
| 21 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 2.23872090 |
| 22 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.21992543 |
| 23 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.15277642 |
| 24 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.11097201 |
| 25 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.90081094 |
| 26 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.86948614 |
| 27 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.79034100 |
| 28 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.74198714 |
| 29 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.73379085 |
| 30 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.71608861 |
| 31 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.67213511 |
| 32 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.67054435 |
| 33 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.65586573 |
| 34 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.64541564 |
| 35 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.58525710 |
| 36 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.57839274 |
| 37 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.52524429 |
| 38 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.50103794 |
| 39 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.45899180 |
| 40 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.43397289 |
| 41 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.43315505 |
| 42 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.42301726 |
| 43 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.42242229 |
| 44 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.42165640 |
| 45 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.40898325 |
| 46 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.37576575 |
| 47 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.35826984 |
| 48 | ELF5_23300383_ChIP-Seq_T47D_Human | 1.34377143 |
| 49 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.33173539 |
| 50 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.32217957 |
| 51 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.31875975 |
| 52 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.31802452 |
| 53 | GATA3_26560356_Chip-Seq_TH2_Human | 1.30984177 |
| 54 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.27614776 |
| 55 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.23495508 |
| 56 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.23079768 |
| 57 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.22511467 |
| 58 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.21005081 |
| 59 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.19712962 |
| 60 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.18620802 |
| 61 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.17709623 |
| 62 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.16851953 |
| 63 | AR_20517297_ChIP-Seq_VCAP_Human | 1.16582015 |
| 64 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.14919836 |
| 65 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.13992491 |
| 66 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.13638864 |
| 67 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.10046633 |
| 68 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.09132063 |
| 69 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.09132063 |
| 70 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.05585096 |
| 71 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.04049685 |
| 72 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.03705825 |
| 73 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.02558060 |
| 74 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.01990582 |
| 75 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.01988620 |
| 76 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.01584410 |
| 77 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.01423852 |
| 78 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.00494068 |
| 79 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 0.99666281 |
| 80 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 0.98115219 |
| 81 | RUNX_20019798_ChIP-Seq_JUKART_Human | 0.97792506 |
| 82 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.97174322 |
| 83 | MYB_26560356_Chip-Seq_TH2_Human | 0.96922848 |
| 84 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.94615653 |
| 85 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.94056771 |
| 86 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 0.94032159 |
| 87 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.93916641 |
| 88 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.93383491 |
| 89 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.92774281 |
| 90 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.92595011 |
| 91 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.92039358 |
| 92 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.91627661 |
| 93 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.91596530 |
| 94 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 0.90410703 |
| 95 | MYB_26560356_Chip-Seq_TH1_Human | 0.90317655 |
| 96 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.89511654 |
| 97 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.88563424 |
| 98 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.88223251 |
| 99 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.87580139 |
| 100 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.87486626 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003806_abnormal_nucleotide_metabolis | 4.39451040 |
| 2 | MP0005083_abnormal_biliary_tract | 3.61829756 |
| 3 | MP0005671_abnormal_response_to | 3.46722747 |
| 4 | MP0005167_abnormal_blood-brain_barrier | 3.04231343 |
| 5 | MP0003786_premature_aging | 2.95423386 |
| 6 | MP0002132_abnormal_respiratory_system | 2.88069867 |
| 7 | MP0001835_abnormal_antigen_presentation | 2.79394524 |
| 8 | MP0002138_abnormal_hepatobiliary_system | 2.64498820 |
| 9 | MP0002148_abnormal_hypersensitivity_rea | 2.63852886 |
| 10 | MP0005058_abnormal_lysosome_morphology | 2.31165417 |
| 11 | MP0000685_abnormal_immune_system | 2.22721283 |
| 12 | MP0004147_increased_porphyrin_level | 2.22160344 |
| 13 | MP0003646_muscle_fatigue | 2.19369616 |
| 14 | MP0003866_abnormal_defecation | 2.06981127 |
| 15 | MP0001853_heart_inflammation | 2.01799410 |
| 16 | MP0000383_abnormal_hair_follicle | 1.98288222 |
| 17 | MP0002419_abnormal_innate_immunity | 1.92906457 |
| 18 | MP0002277_abnormal_respiratory_mucosa | 1.85398201 |
| 19 | MP0005084_abnormal_gallbladder_morpholo | 1.83395692 |
| 20 | MP0004484_altered_response_of | 1.78206414 |
| 21 | MP0006082_CNS_inflammation | 1.77132240 |
| 22 | MP0004145_abnormal_muscle_electrophysio | 1.75357006 |
| 23 | MP0005025_abnormal_response_to | 1.75198776 |
| 24 | MP0009785_altered_susceptibility_to | 1.57070934 |
| 25 | MP0002420_abnormal_adaptive_immunity | 1.56283208 |
| 26 | MP0005646_abnormal_pituitary_gland | 1.55389784 |
| 27 | MP0002452_abnormal_antigen_presenting | 1.55331569 |
| 28 | MP0000604_amyloidosis | 1.54800519 |
| 29 | MP0005000_abnormal_immune_tolerance | 1.54254555 |
| 30 | MP0001819_abnormal_immune_cell | 1.53420573 |
| 31 | MP0005410_abnormal_fertilization | 1.51185220 |
| 32 | MP0000343_altered_response_to | 1.50778949 |
| 33 | MP0002723_abnormal_immune_serum | 1.50772191 |
| 34 | MP0004134_abnormal_chest_morphology | 1.49424859 |
| 35 | MP0000749_muscle_degeneration | 1.46029876 |
| 36 | MP0004510_myositis | 1.45966437 |
| 37 | MP0008875_abnormal_xenobiotic_pharmacok | 1.44943058 |
| 38 | MP0001800_abnormal_humoral_immune | 1.43849386 |
| 39 | MP0003724_increased_susceptibility_to | 1.39571680 |
| 40 | MP0003567_abnormal_fetal_cardiomyocyte | 1.38441718 |
| 41 | MP0008877_abnormal_DNA_methylation | 1.27494443 |
| 42 | MP0008995_early_reproductive_senescence | 1.25779378 |
| 43 | MP0005387_immune_system_phenotype | 1.25696187 |
| 44 | MP0001790_abnormal_immune_system | 1.25696187 |
| 45 | MP0000716_abnormal_immune_system | 1.23683838 |
| 46 | MP0004742_abnormal_vestibular_system | 1.23573161 |
| 47 | MP0003303_peritoneal_inflammation | 1.21614238 |
| 48 | MP0009333_abnormal_splenocyte_physiolog | 1.19454152 |
| 49 | MP0002160_abnormal_reproductive_system | 1.18431169 |
| 50 | MP0003195_calcinosis | 1.18020336 |
| 51 | MP0010678_abnormal_skin_adnexa | 1.17370175 |
| 52 | MP0000920_abnormal_myelination | 1.16360202 |
| 53 | MP0002405_respiratory_system_inflammati | 1.16082808 |
| 54 | MP0001845_abnormal_inflammatory_respons | 1.11598853 |
| 55 | MP0005075_abnormal_melanosome_morpholog | 1.11083913 |
| 56 | MP0001542_abnormal_bone_strength | 1.10760139 |
| 57 | MP0005332_abnormal_amino_acid | 1.10630988 |
| 58 | MP0001440_abnormal_grooming_behavior | 1.09861166 |
| 59 | MP0004947_skin_inflammation | 1.09399285 |
| 60 | MP0005365_abnormal_bile_salt | 1.06065632 |
| 61 | MP0005389_reproductive_system_phenotype | 1.05655649 |
| 62 | MP0004142_abnormal_muscle_tone | 1.04834260 |
| 63 | MP0005379_endocrine/exocrine_gland_phen | 1.04459354 |
| 64 | MP0000689_abnormal_spleen_morphology | 1.03840016 |
| 65 | MP0002429_abnormal_blood_cell | 1.03710451 |
| 66 | MP0002876_abnormal_thyroid_physiology | 1.02853799 |
| 67 | MP0002102_abnormal_ear_morphology | 1.02059505 |
| 68 | MP0003436_decreased_susceptibility_to | 1.01162923 |
| 69 | MP0001545_abnormal_hematopoietic_system | 0.98751529 |
| 70 | MP0005397_hematopoietic_system_phenotyp | 0.98751529 |
| 71 | MP0008469_abnormal_protein_level | 0.98403239 |
| 72 | MP0002398_abnormal_bone_marrow | 0.97910650 |
| 73 | MP0000858_altered_metastatic_potential | 0.95627891 |
| 74 | MP0002837_dystrophic_cardiac_calcinosis | 0.95488966 |
| 75 | MP0006035_abnormal_mitochondrial_morpho | 0.95395003 |
| 76 | MP0003763_abnormal_thymus_physiology | 0.95300181 |
| 77 | MP0003329_amyloid_beta_deposits | 0.93925399 |
| 78 | MP0005464_abnormal_platelet_physiology | 0.93399327 |
| 79 | MP0002722_abnormal_immune_system | 0.91977152 |
| 80 | MP0003315_abnormal_perineum_morphology | 0.91593435 |
| 81 | MP0009765_abnormal_xenobiotic_induced | 0.90631164 |
| 82 | MP0005266_abnormal_metabolism | 0.89306451 |
| 83 | MP0005330_cardiomyopathy | 0.87730806 |
| 84 | MP0003959_abnormal_lean_body | 0.87069343 |
| 85 | MP0006036_abnormal_mitochondrial_physio | 0.85661653 |
| 86 | MP0000490_abnormal_crypts_of | 0.84462029 |
| 87 | MP0002229_neurodegeneration | 0.82301846 |
| 88 | MP0002163_abnormal_gland_morphology | 0.81889669 |
| 89 | MP0005310_abnormal_salivary_gland | 0.81385329 |
| 90 | MP0000613_abnormal_salivary_gland | 0.80813317 |
| 91 | MP0004381_abnormal_hair_follicle | 0.80432172 |
| 92 | MP0003638_abnormal_response/metabolism_ | 0.80407318 |
| 93 | MP0000647_abnormal_sebaceous_gland | 0.79942641 |
| 94 | MP0002332_abnormal_exercise_endurance | 0.79126745 |
| 95 | MP0009764_decreased_sensitivity_to | 0.78319970 |
| 96 | MP0006292_abnormal_olfactory_placode | 0.77668947 |
| 97 | MP0003186_abnormal_redox_activity | 0.75602329 |
| 98 | MP0002090_abnormal_vision | 0.75180039 |
| 99 | MP0005551_abnormal_eye_electrophysiolog | 0.74450353 |
| 100 | MP0009278_abnormal_bone_marrow | 0.74361475 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Increased hepatocellular lipid droplets (HP:0006565) | 3.92084076 |
| 2 | Lipid accumulation in hepatocytes (HP:0006561) | 3.89224031 |
| 3 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.79983735 |
| 4 | Acute necrotizing encephalopathy (HP:0006965) | 3.57734989 |
| 5 | Abnormality of the renal collecting system (HP:0004742) | 3.57587258 |
| 6 | Renal Fanconi syndrome (HP:0001994) | 3.55962428 |
| 7 | Duplicated collecting system (HP:0000081) | 3.45174238 |
| 8 | Onycholysis (HP:0001806) | 3.41196838 |
| 9 | Loss of speech (HP:0002371) | 3.39384865 |
| 10 | Adactyly (HP:0009776) | 3.38321032 |
| 11 | Vacuolated lymphocytes (HP:0001922) | 3.37600803 |
| 12 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.37235311 |
| 13 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.27923023 |
| 14 | Mitochondrial inheritance (HP:0001427) | 3.25539643 |
| 15 | Reticulocytopenia (HP:0001896) | 3.20199773 |
| 16 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 3.15972155 |
| 17 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 3.14673834 |
| 18 | Hypoplasia of the uterus (HP:0000013) | 3.09958318 |
| 19 | Increased CSF lactate (HP:0002490) | 3.09064041 |
| 20 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.06535678 |
| 21 | Abnormality of alanine metabolism (HP:0010916) | 3.06535678 |
| 22 | Hyperalaninemia (HP:0003348) | 3.06535678 |
| 23 | Increased cerebral lipofuscin (HP:0011813) | 3.05577720 |
| 24 | Confusion (HP:0001289) | 3.01389238 |
| 25 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 3.00833396 |
| 26 | Stomatitis (HP:0010280) | 2.99356132 |
| 27 | Progressive macrocephaly (HP:0004481) | 2.94754475 |
| 28 | Paralysis (HP:0003470) | 2.91341031 |
| 29 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.90668860 |
| 30 | Absent phalangeal crease (HP:0006109) | 2.86907021 |
| 31 | Acute encephalopathy (HP:0006846) | 2.83288809 |
| 32 | Increased intramyocellular lipid droplets (HP:0012240) | 2.81041990 |
| 33 | Abnormality of glycolipid metabolism (HP:0010969) | 2.80721043 |
| 34 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.80721043 |
| 35 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.80721043 |
| 36 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.75116672 |
| 37 | Increased serum lactate (HP:0002151) | 2.66678298 |
| 38 | Abnormal finger flexion creases (HP:0006143) | 2.65656013 |
| 39 | Porencephaly (HP:0002132) | 2.59491653 |
| 40 | Abolished electroretinogram (ERG) (HP:0000550) | 2.58233232 |
| 41 | Exertional dyspnea (HP:0002875) | 2.57552999 |
| 42 | 3-Methylglutaconic aciduria (HP:0003535) | 2.56483914 |
| 43 | Polycythemia (HP:0001901) | 2.52128913 |
| 44 | Increased muscle lipid content (HP:0009058) | 2.50767736 |
| 45 | Petechiae (HP:0000967) | 2.44479581 |
| 46 | Microretrognathia (HP:0000308) | 2.43770556 |
| 47 | Glycosuria (HP:0003076) | 2.40239054 |
| 48 | Abnormality of urine glucose concentration (HP:0011016) | 2.40239054 |
| 49 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 2.38790689 |
| 50 | Cerebral edema (HP:0002181) | 2.38735897 |
| 51 | Reduced antithrombin III activity (HP:0001976) | 2.38391599 |
| 52 | Abnormal number of erythroid precursors (HP:0012131) | 2.38369650 |
| 53 | Lactic acidosis (HP:0003128) | 2.30115189 |
| 54 | Ureteral stenosis (HP:0000071) | 2.30031982 |
| 55 | Respiratory difficulties (HP:0002880) | 2.28107096 |
| 56 | Thrombocytosis (HP:0001894) | 2.23668087 |
| 57 | Pendular nystagmus (HP:0012043) | 2.23635375 |
| 58 | Autoimmune thrombocytopenia (HP:0001973) | 2.23262032 |
| 59 | Macrocytic anemia (HP:0001972) | 2.21395495 |
| 60 | Optic disc pallor (HP:0000543) | 2.20874573 |
| 61 | Tongue fasciculations (HP:0001308) | 2.20076195 |
| 62 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.16439036 |
| 63 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.13157006 |
| 64 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 2.11149052 |
| 65 | IgG deficiency (HP:0004315) | 2.10985367 |
| 66 | Pancreatic cysts (HP:0001737) | 2.10712796 |
| 67 | Abnormality of renal resorption (HP:0011038) | 2.09632301 |
| 68 | Broad-based gait (HP:0002136) | 2.09519148 |
| 69 | Ureteral obstruction (HP:0006000) | 2.07181029 |
| 70 | Hypergonadotropic hypogonadism (HP:0000815) | 2.06653707 |
| 71 | Testicular atrophy (HP:0000029) | 2.06487245 |
| 72 | Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161) | 2.05510937 |
| 73 | Lethargy (HP:0001254) | 2.04502443 |
| 74 | Respiratory failure (HP:0002878) | 2.03819420 |
| 75 | Ureteral duplication (HP:0000073) | 2.02944823 |
| 76 | Palpitations (HP:0001962) | 2.02499216 |
| 77 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.01305782 |
| 78 | Constricted visual fields (HP:0001133) | 2.00791708 |
| 79 | Type I transferrin isoform profile (HP:0003642) | 1.98937111 |
| 80 | Anhidrosis (HP:0000970) | 1.98415131 |
| 81 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 1.96359561 |
| 82 | Disinhibition (HP:0000734) | 1.94729841 |
| 83 | Myositis (HP:0100614) | 1.93140107 |
| 84 | Methylmalonic aciduria (HP:0012120) | 1.92007584 |
| 85 | Abnormality of midbrain morphology (HP:0002418) | 1.88700243 |
| 86 | Molar tooth sign on MRI (HP:0002419) | 1.88700243 |
| 87 | Small hand (HP:0200055) | 1.88458901 |
| 88 | Muscle fibrillation (HP:0010546) | 1.85795656 |
| 89 | Conjunctival hamartoma (HP:0100780) | 1.84993068 |
| 90 | Exercise intolerance (HP:0003546) | 1.83510488 |
| 91 | Increased corneal curvature (HP:0100692) | 1.83160671 |
| 92 | Keratoconus (HP:0000563) | 1.83160671 |
| 93 | Congenital stationary night blindness (HP:0007642) | 1.82396285 |
| 94 | Recurrent abscess formation (HP:0002722) | 1.80761626 |
| 95 | Posterior subcapsular cataract (HP:0007787) | 1.80640196 |
| 96 | Abnormality of the middle phalanges of the toes (HP:0010183) | 1.79006278 |
| 97 | Agitation (HP:0000713) | 1.77674841 |
| 98 | Mediastinal lymphadenopathy (HP:0100721) | 1.77168223 |
| 99 | Palpebral edema (HP:0100540) | 1.76726426 |
| 100 | Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376) | 1.76035674 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 6.73758338 |
| 2 | TAOK3 | 4.45742686 |
| 3 | NME2 | 4.22058531 |
| 4 | PBK | 4.00724696 |
| 5 | BCKDK | 3.28256336 |
| 6 | STK16 | 3.27490159 |
| 7 | GRK7 | 3.04561552 |
| 8 | SCYL2 | 2.98846631 |
| 9 | TGFBR2 | 2.41773271 |
| 10 | TIE1 | 2.38503261 |
| 11 | MOS | 2.34761434 |
| 12 | EIF2AK1 | 2.04853010 |
| 13 | MST4 | 1.87458643 |
| 14 | NUAK1 | 1.77172189 |
| 15 | ACVR1B | 1.72710124 |
| 16 | MAP3K6 | 1.56041073 |
| 17 | MAP2K3 | 1.54473383 |
| 18 | ZAK | 1.53357514 |
| 19 | LMTK2 | 1.50057298 |
| 20 | PLK4 | 1.47171317 |
| 21 | MAP2K6 | 1.42744329 |
| 22 | FES | 1.29484461 |
| 23 | GRK5 | 1.27977687 |
| 24 | MAP4K1 | 1.24583541 |
| 25 | TESK2 | 1.21912006 |
| 26 | GRK1 | 1.21655219 |
| 27 | MAPK13 | 1.07800663 |
| 28 | TYK2 | 1.01218935 |
| 29 | WNK4 | 0.98341970 |
| 30 | TBK1 | 0.95463944 |
| 31 | ADRBK2 | 0.94868623 |
| 32 | PHKG2 | 0.93549603 |
| 33 | PHKG1 | 0.93549603 |
| 34 | CDK19 | 0.93300822 |
| 35 | DAPK1 | 0.92087156 |
| 36 | VRK2 | 0.91492397 |
| 37 | STK10 | 0.90669501 |
| 38 | MAPK7 | 0.86314143 |
| 39 | LIMK1 | 0.81174248 |
| 40 | SRPK1 | 0.78948838 |
| 41 | TGFBR1 | 0.76492779 |
| 42 | CSF1R | 0.75790314 |
| 43 | PINK1 | 0.74224225 |
| 44 | DAPK2 | 0.73683086 |
| 45 | KIT | 0.73601886 |
| 46 | OXSR1 | 0.72859328 |
| 47 | ITK | 0.71235748 |
| 48 | EIF2AK2 | 0.69854821 |
| 49 | NEK9 | 0.65874767 |
| 50 | ZAP70 | 0.64707619 |
| 51 | EPHB2 | 0.64155860 |
| 52 | IKBKE | 0.62745951 |
| 53 | KSR1 | 0.62440660 |
| 54 | ABL2 | 0.61400674 |
| 55 | IKBKB | 0.60869369 |
| 56 | JAK3 | 0.59740878 |
| 57 | ADRBK1 | 0.59644303 |
| 58 | PDK2 | 0.57519849 |
| 59 | BMPR1B | 0.55679442 |
| 60 | TEC | 0.55499661 |
| 61 | MAP4K2 | 0.54147566 |
| 62 | TSSK6 | 0.52142361 |
| 63 | IGF1R | 0.51552246 |
| 64 | MAP2K4 | 0.51527150 |
| 65 | BLK | 0.51047077 |
| 66 | CDK8 | 0.49017113 |
| 67 | LYN | 0.48530129 |
| 68 | FRK | 0.46991015 |
| 69 | PIK3CA | 0.46825967 |
| 70 | ILK | 0.45836193 |
| 71 | STK39 | 0.45753820 |
| 72 | MAP3K5 | 0.45447310 |
| 73 | PRKCQ | 0.44842146 |
| 74 | PRKG2 | 0.43188577 |
| 75 | SYK | 0.42291969 |
| 76 | CAMKK2 | 0.39145104 |
| 77 | EIF2AK3 | 0.36510410 |
| 78 | TAF1 | 0.33355418 |
| 79 | MINK1 | 0.33303592 |
| 80 | MARK3 | 0.33096408 |
| 81 | PLK3 | 0.32072199 |
| 82 | LCK | 0.31982902 |
| 83 | AURKA | 0.31904496 |
| 84 | PIK3CG | 0.30797369 |
| 85 | FYN | 0.30427378 |
| 86 | CAMK1D | 0.29976748 |
| 87 | VRK1 | 0.29847328 |
| 88 | OBSCN | 0.28748234 |
| 89 | CSNK1G3 | 0.28214433 |
| 90 | STK24 | 0.27907930 |
| 91 | MAPKAPK3 | 0.27820602 |
| 92 | TLK1 | 0.27524539 |
| 93 | CSNK1G2 | 0.27181963 |
| 94 | RIPK4 | 0.26452003 |
| 95 | PDK1 | 0.25754556 |
| 96 | RPS6KB1 | 0.23991802 |
| 97 | INSRR | 0.22923979 |
| 98 | PRKCD | 0.20124155 |
| 99 | BUB1 | 0.19900197 |
| 100 | EGFR | 0.18919292 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.84107858 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.28687219 |
| 3 | Proteasome_Homo sapiens_hsa03050 | 3.10136341 |
| 4 | Asthma_Homo sapiens_hsa05310 | 2.87663220 |
| 5 | Sulfur metabolism_Homo sapiens_hsa00920 | 2.74857569 |
| 6 | RNA degradation_Homo sapiens_hsa03018 | 2.53730864 |
| 7 | Parkinsons disease_Homo sapiens_hsa05012 | 2.44638881 |
| 8 | Sulfur relay system_Homo sapiens_hsa04122 | 2.43983548 |
| 9 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.16619549 |
| 10 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.12489884 |
| 11 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.01201695 |
| 12 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.96042314 |
| 13 | Protein export_Homo sapiens_hsa03060 | 1.95694789 |
| 14 | RNA polymerase_Homo sapiens_hsa03020 | 1.91985510 |
| 15 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.90136614 |
| 16 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.89480371 |
| 17 | Spliceosome_Homo sapiens_hsa03040 | 1.81390079 |
| 18 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.76659556 |
| 19 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.75903720 |
| 20 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.70033042 |
| 21 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.69171247 |
| 22 | Alzheimers disease_Homo sapiens_hsa05010 | 1.67211001 |
| 23 | Huntingtons disease_Homo sapiens_hsa05016 | 1.64040883 |
| 24 | Allograft rejection_Homo sapiens_hsa05330 | 1.63580544 |
| 25 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.62838166 |
| 26 | Lysosome_Homo sapiens_hsa04142 | 1.53788350 |
| 27 | DNA replication_Homo sapiens_hsa03030 | 1.50068207 |
| 28 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.49972522 |
| 29 | Phototransduction_Homo sapiens_hsa04744 | 1.48226981 |
| 30 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.46206433 |
| 31 | Peroxisome_Homo sapiens_hsa04146 | 1.35254923 |
| 32 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.33322132 |
| 33 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.31604817 |
| 34 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.27749618 |
| 35 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.26519140 |
| 36 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.25784219 |
| 37 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.24395346 |
| 38 | Purine metabolism_Homo sapiens_hsa00230 | 1.22072001 |
| 39 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.15492696 |
| 40 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.06425724 |
| 41 | Basal transcription factors_Homo sapiens_hsa03022 | 1.04847511 |
| 42 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.03806028 |
| 43 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.01828719 |
| 44 | RNA transport_Homo sapiens_hsa03013 | 1.00289087 |
| 45 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.99784136 |
| 46 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.97298479 |
| 47 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.97132811 |
| 48 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.93153750 |
| 49 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.91479491 |
| 50 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.90474738 |
| 51 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.90259128 |
| 52 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.85747654 |
| 53 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.84436524 |
| 54 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.83688197 |
| 55 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.78827942 |
| 56 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.75339650 |
| 57 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.74291563 |
| 58 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.70410126 |
| 59 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.67603461 |
| 60 | Viral myocarditis_Homo sapiens_hsa05416 | 0.67039676 |
| 61 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.65163183 |
| 62 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.64792009 |
| 63 | Retinol metabolism_Homo sapiens_hsa00830 | 0.63719925 |
| 64 | Metabolic pathways_Homo sapiens_hsa01100 | 0.57076447 |
| 65 | Leishmaniasis_Homo sapiens_hsa05140 | 0.53891212 |
| 66 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.52431477 |
| 67 | Phagosome_Homo sapiens_hsa04145 | 0.51829202 |
| 68 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.51703479 |
| 69 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.51185599 |
| 70 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.50975977 |
| 71 | Mineral absorption_Homo sapiens_hsa04978 | 0.50921406 |
| 72 | Tuberculosis_Homo sapiens_hsa05152 | 0.49864330 |
| 73 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.45965467 |
| 74 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.45624530 |
| 75 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.44848207 |
| 76 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.44767592 |
| 77 | Salivary secretion_Homo sapiens_hsa04970 | 0.44554538 |
| 78 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.42047236 |
| 79 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.40459332 |
| 80 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.39660991 |
| 81 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.37945514 |
| 82 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.37580604 |
| 83 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.37335456 |
| 84 | Base excision repair_Homo sapiens_hsa03410 | 0.37157164 |
| 85 | Legionellosis_Homo sapiens_hsa05134 | 0.36971763 |
| 86 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.35581235 |
| 87 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.34629648 |
| 88 | Nicotine addiction_Homo sapiens_hsa05033 | 0.34189840 |
| 89 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.33847674 |
| 90 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.33071499 |
| 91 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.32494096 |
| 92 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.30110698 |
| 93 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.30108338 |
| 94 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.29756407 |
| 95 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.28818787 |
| 96 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.27917816 |
| 97 | Measles_Homo sapiens_hsa05162 | 0.25438321 |
| 98 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.23898248 |
| 99 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.23160388 |
| 100 | Homologous recombination_Homo sapiens_hsa03440 | 0.22190159 |

