BUB3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a protein involved in spindle checkpoint function. The encoded protein contains four WD repeat domains and has sequence similarity with the yeast BUB3 protein. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein localization to kinetochore (GO:0034501)4.99922207
2mitotic metaphase plate congression (GO:0007080)4.72153822
3telomere maintenance via semi-conservative replication (GO:0032201)4.70395208
4DNA strand elongation involved in DNA replication (GO:0006271)4.69314708
5CENP-A containing nucleosome assembly (GO:0034080)4.61118892
6ribosomal small subunit assembly (GO:0000028)4.53374697
7DNA strand elongation (GO:0022616)4.46393618
8kinetochore organization (GO:0051383)4.42035189
9chromatin remodeling at centromere (GO:0031055)4.40297137
10protein localization to chromosome, centromeric region (GO:0071459)4.38457946
11telomere maintenance via recombination (GO:0000722)4.22283491
12metaphase plate congression (GO:0051310)4.17556193
13DNA unwinding involved in DNA replication (GO:0006268)4.16989293
14DNA replication initiation (GO:0006270)4.12578635
15mitotic recombination (GO:0006312)4.09989977
16* mitotic sister chromatid segregation (GO:0000070)4.03260426
17establishment of chromosome localization (GO:0051303)4.01357978
18kinetochore assembly (GO:0051382)3.98519897
19viral transcription (GO:0019083)3.98317123
20DNA replication-independent nucleosome assembly (GO:0006336)3.94063612
21DNA replication-independent nucleosome organization (GO:0034724)3.94063612
22translational termination (GO:0006415)3.92893317
23* anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.89051152
24regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.87826003
25* attachment of spindle microtubules to kinetochore (GO:0008608)3.85617848
26DNA double-strand break processing (GO:0000729)3.85374916
27maturation of SSU-rRNA (GO:0030490)3.85191642
28* negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.83469138
29mitotic chromosome condensation (GO:0007076)3.83290084
30ribosomal large subunit biogenesis (GO:0042273)3.82153743
31nucleotide-excision repair, DNA gap filling (GO:0006297)3.80318198
32telomere maintenance via telomere lengthening (GO:0010833)3.79449983
33regulation of spindle organization (GO:0090224)3.78324588
34ribosomal small subunit biogenesis (GO:0042274)3.75103754
35ribosome assembly (GO:0042255)3.74871009
36* regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.74782394
37positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.74589468
38proteasome assembly (GO:0043248)3.72128136
39* regulation of mitotic metaphase/anaphase transition (GO:0030071)3.70376675
40* regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.70376675
41formation of translation preinitiation complex (GO:0001731)3.68789275
42* sister chromatid segregation (GO:0000819)3.68338269
43DNA replication checkpoint (GO:0000076)3.66780387
44histone exchange (GO:0043486)3.64734255
45* regulation of sister chromatid segregation (GO:0033045)3.61551054
46* regulation of mitotic sister chromatid separation (GO:0010965)3.61551054
47* regulation of mitotic sister chromatid segregation (GO:0033047)3.61551054
48translational elongation (GO:0006414)3.57479286
49mitotic nuclear envelope disassembly (GO:0007077)3.56536732
50* negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.52763965
51* negative regulation of ligase activity (GO:0051352)3.52763965
52establishment of integrated proviral latency (GO:0075713)3.51990244
53nucleobase biosynthetic process (GO:0046112)3.51560008
54DNA deamination (GO:0045006)3.50546891
55SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.48712196
56DNA catabolic process, exonucleolytic (GO:0000738)3.48170578
57cotranslational protein targeting to membrane (GO:0006613)3.47773502
58translational initiation (GO:0006413)3.43726091
59* spindle checkpoint (GO:0031577)3.41552625
60protein targeting to ER (GO:0045047)3.39980958
61DNA replication-dependent nucleosome assembly (GO:0006335)3.37974326
62DNA replication-dependent nucleosome organization (GO:0034723)3.37974326
63mitotic sister chromatid cohesion (GO:0007064)3.36079572
64negative regulation of DNA-dependent DNA replication (GO:2000104)3.35910806
65purine nucleobase biosynthetic process (GO:0009113)3.35836860
66establishment of protein localization to mitochondrial membrane (GO:0090151)3.35675778
67establishment of viral latency (GO:0019043)3.35548545
68nuclear pore complex assembly (GO:0051292)3.35330146
69ribonucleoprotein complex biogenesis (GO:0022613)3.34577999
70protein K6-linked ubiquitination (GO:0085020)3.34577481
71transcription-coupled nucleotide-excision repair (GO:0006283)3.34571880
72cullin deneddylation (GO:0010388)3.31344691
73replication fork processing (GO:0031297)3.29805283
74mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.29772115
75regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.29035865
76regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.28706019
77regulation of mitotic spindle checkpoint (GO:1903504)3.28706019
78spliceosomal snRNP assembly (GO:0000387)3.28044178
79cellular protein complex disassembly (GO:0043624)3.27101202
80nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.25596169
81membrane disassembly (GO:0030397)3.25030957
82nuclear envelope disassembly (GO:0051081)3.25030957
83* negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.24070875
84* negative regulation of sister chromatid segregation (GO:0033046)3.24070875
85* negative regulation of mitotic sister chromatid separation (GO:2000816)3.24070875
86* negative regulation of mitotic sister chromatid segregation (GO:0033048)3.24070875
87IMP biosynthetic process (GO:0006188)3.23911712
88DNA topological change (GO:0006265)3.23785055
89positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.23443990
90regulation of DNA endoreduplication (GO:0032875)3.22848318
91establishment of protein localization to endoplasmic reticulum (GO:0072599)3.22518929
92nuclear pore organization (GO:0006999)3.22405898
93* negative regulation of chromosome segregation (GO:0051985)3.21918509
94protein localization to endoplasmic reticulum (GO:0070972)3.21695952
95* spindle assembly checkpoint (GO:0071173)3.21174378
96protein deneddylation (GO:0000338)3.20754131
97* negative regulation of mitosis (GO:0045839)3.19930586
98cell cycle G1/S phase transition (GO:0044843)3.19709468
99G1/S transition of mitotic cell cycle (GO:0000082)3.19709468
100rRNA processing (GO:0006364)3.19230704
101* regulation of ubiquitin-protein transferase activity (GO:0051438)3.18878379
102DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.18510790
103* regulation of chromosome segregation (GO:0051983)3.17779650
104* negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.16559119
105regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.16182516
106regulation of mitotic spindle organization (GO:0060236)3.15937981
107regulation of centriole replication (GO:0046599)3.15834126
108viral life cycle (GO:0019058)3.15001096
109* mitotic spindle assembly checkpoint (GO:0007094)3.13802356
110intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.13307717
111signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.13307717
112non-recombinational repair (GO:0000726)3.11624050
113double-strand break repair via nonhomologous end joining (GO:0006303)3.11624050
114deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.10980537
115signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.10652758
116signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.10652758
117signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.10652758
118protein localization to chromosome (GO:0034502)3.10575652
119positive regulation of ligase activity (GO:0051351)3.10380605
120* chromosome segregation (GO:0007059)3.09323380
121DNA ligation (GO:0006266)3.07385902
122* regulation of ligase activity (GO:0051340)3.07146771
123positive regulation of chromosome segregation (GO:0051984)3.07109938
124rRNA metabolic process (GO:0016072)3.06678087
125termination of RNA polymerase III transcription (GO:0006386)3.06528882
126transcription elongation from RNA polymerase III promoter (GO:0006385)3.06528882
127folic acid-containing compound biosynthetic process (GO:0009396)3.06509789
128* mitotic spindle checkpoint (GO:0071174)3.06416776
129signal transduction involved in DNA integrity checkpoint (GO:0072401)3.05654214

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.81043251
2FOXM1_23109430_ChIP-Seq_U2OS_Human5.10396708
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.25660810
4* E2F4_17652178_ChIP-ChIP_JURKAT_Human4.00515306
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.99981128
6* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.72706166
7EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.72365431
8* EST1_17652178_ChIP-ChIP_JURKAT_Human3.46418013
9GABP_17652178_ChIP-ChIP_JURKAT_Human3.27188752
10JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.09557732
11* ETS1_20019798_ChIP-Seq_JURKAT_Human3.06440004
12* CREB1_15753290_ChIP-ChIP_HEK293T_Human2.95623991
13MYC_19079543_ChIP-ChIP_MESCs_Mouse2.89393904
14MYC_18358816_ChIP-ChIP_MESCs_Mouse2.88224426
15* HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.84714074
16MYC_19030024_ChIP-ChIP_MESCs_Mouse2.83137157
17SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.72855451
18* NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.68409514
19CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.64466519
20XRN2_22483619_ChIP-Seq_HELA_Human2.52332386
21VDR_23849224_ChIP-Seq_CD4+_Human2.42049715
22MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.41700382
23* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.41196658
24ELF1_17652178_ChIP-ChIP_JURKAT_Human2.33505148
25* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.24149641
26FOXP3_21729870_ChIP-Seq_TREG_Human2.19416017
27AR_21909140_ChIP-Seq_LNCAP_Human2.18340470
28* DCP1A_22483619_ChIP-Seq_HELA_Human2.17426727
29E2F1_18555785_ChIP-Seq_MESCs_Mouse2.12946614
30* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.11633093
31* THAP11_20581084_ChIP-Seq_MESCs_Mouse2.10342380
32TTF2_22483619_ChIP-Seq_HELA_Human2.00509993
33* GABP_19822575_ChIP-Seq_HepG2_Human1.96272407
34ELK1_19687146_ChIP-ChIP_HELA_Human1.90582513
35* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.86901344
36* E2F1_21310950_ChIP-Seq_MCF-7_Human1.83354026
37FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.80777354
38HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.79451535
39PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.78001058
40CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.73879450
41MYCN_18555785_ChIP-Seq_MESCs_Mouse1.73859023
42HOXB4_20404135_ChIP-ChIP_EML_Mouse1.72582502
43CIITA_25753668_ChIP-Seq_RAJI_Human1.69991916
44YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.69706451
45SALL1_21062744_ChIP-ChIP_HESCs_Human1.67155414
46POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.67073097
47ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.64007297
48YY1_21170310_ChIP-Seq_MESCs_Mouse1.62299638
49TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.62214706
50SRF_21415370_ChIP-Seq_HL-1_Mouse1.60589071
51NANOG_18555785_ChIP-Seq_MESCs_Mouse1.59866904
52E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.58612177
53MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.58560787
54PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.54374603
55* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.47233744
56* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.44922078
57CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.44700111
58KDM5A_27292631_Chip-Seq_BREAST_Human1.44293257
59FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.37557215
60* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.36303859
61* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.29648330
62EGR1_19374776_ChIP-ChIP_THP-1_Human1.27514598
63* SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.26895054
64* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.25555955
65* EWS_26573619_Chip-Seq_HEK293_Human1.25424198
66PADI4_21655091_ChIP-ChIP_MCF-7_Human1.23819350
67POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.20969558
68CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.18917607
69SOX2_18555785_ChIP-Seq_MESCs_Mouse1.13742978
70KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.11907076
71* MYC_18940864_ChIP-ChIP_HL60_Human1.11430391
72ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.10022594
73MYC_22102868_ChIP-Seq_BL_Human1.09813954
74* NANOG_16153702_ChIP-ChIP_HESCs_Human1.07338733
75* POU5F1_16153702_ChIP-ChIP_HESCs_Human1.07254196
76TP63_19390658_ChIP-ChIP_HaCaT_Human1.06585050
77ELK1_22589737_ChIP-Seq_MCF10A_Human1.05592331
78ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.04869565
79* TFEB_21752829_ChIP-Seq_HELA_Human1.03617487
80CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.01711300
81CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.01519303
82* SOX2_16153702_ChIP-ChIP_HESCs_Human1.00170695
83GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.99042830
84KLF4_18555785_ChIP-Seq_MESCs_Mouse0.98299007
85SPI1_23547873_ChIP-Seq_NB4_Human0.96615002
86PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.96059501
87DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.95423464
88CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.94640983
89BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.94504992
90* FUS_26573619_Chip-Seq_HEK293_Human0.92418284
91RBPJ_22232070_ChIP-Seq_NCS_Mouse0.92363775
92VDR_22108803_ChIP-Seq_LS180_Human0.91109563
93POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.90202235
94* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.90191518
95VDR_21846776_ChIP-Seq_THP-1_Human0.87693277
96HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.86756333
97HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.82911785
98CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.82869641
99IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.82744330
100* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.82622280
101IRF1_19129219_ChIP-ChIP_H3396_Human0.82247141
102ZNF274_21170338_ChIP-Seq_K562_Hela0.78967756
103FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.78615590
104* SOX17_20123909_ChIP-Seq_XEN_Mouse0.77328036
105* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.76651871
106KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.76446674
107NOTCH1_21737748_ChIP-Seq_TLL_Human0.75642710
108CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.75223691
109STAT3_1855785_ChIP-Seq_MESCs_Mouse0.75088740
110SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.73853603
111CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.72518236
112SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.70040423
113SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.67212039
114TBX5_21415370_ChIP-Seq_HL-1_Mouse0.66390380
115NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.64916298

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.66970315
2MP0010094_abnormal_chromosome_stability4.88545523
3* MP0004957_abnormal_blastocyst_morpholog4.59223007
4* MP0003111_abnormal_nucleus_morphology4.50743935
5* MP0003077_abnormal_cell_cycle4.37723817
6MP0008057_abnormal_DNA_replication3.56686434
7MP0008058_abnormal_DNA_repair3.43389189
8MP0008932_abnormal_embryonic_tissue3.19021888
9MP0003123_paternal_imprinting2.80599254
10* MP0008007_abnormal_cellular_replicative2.73181796
11MP0002396_abnormal_hematopoietic_system2.34908549
12MP0008877_abnormal_DNA_methylation2.20670327
13MP0003941_abnormal_skin_development2.17721975
14MP0001730_embryonic_growth_arrest2.17152081
15* MP0000350_abnormal_cell_proliferation2.04907718
16MP0003121_genomic_imprinting1.81697032
17MP0009379_abnormal_foot_pigmentation1.73241735
18MP0006292_abnormal_olfactory_placode1.68310766
19MP0000490_abnormal_crypts_of1.67466539
20MP0010030_abnormal_orbit_morphology1.65538561
21MP0003718_maternal_effect1.63587089
22MP0003806_abnormal_nucleotide_metabolis1.63165160
23MP0001697_abnormal_embryo_size1.60144644
24MP0004808_abnormal_hematopoietic_stem1.48788778
25* MP0002080_prenatal_lethality1.47550328
26MP0000313_abnormal_cell_death1.46268217
27* MP0003786_premature_aging1.45690185
28MP0009333_abnormal_splenocyte_physiolog1.44630552
29* MP0002019_abnormal_tumor_incidence1.42155471
30MP0001672_abnormal_embryogenesis/_devel1.35893843
31MP0005380_embryogenesis_phenotype1.35893843
32MP0006072_abnormal_retinal_apoptosis1.34768808
33* MP0002085_abnormal_embryonic_tissue1.32598338
34MP0010307_abnormal_tumor_latency1.31361873
35MP0002938_white_spotting1.29428441
36MP0006054_spinal_hemorrhage1.27918460
37MP0003315_abnormal_perineum_morphology1.27569524
38MP0001529_abnormal_vocalization1.25240143
39MP0003763_abnormal_thymus_physiology1.25190217
40MP0000703_abnormal_thymus_morphology1.23115862
41MP0002398_abnormal_bone_marrow1.19371790
42MP0001346_abnormal_lacrimal_gland1.19094376
43MP0003984_embryonic_growth_retardation1.17625333
44MP0009672_abnormal_birth_weight1.16792377
45MP0002210_abnormal_sex_determination1.16769099
46MP0002234_abnormal_pharynx_morphology1.13877800
47MP0002088_abnormal_embryonic_growth/wei1.12705556
48MP0002722_abnormal_immune_system1.08925903
49MP0002084_abnormal_developmental_patter1.07392059
50MP0002132_abnormal_respiratory_system1.03865614
51MP0000689_abnormal_spleen_morphology1.03518235
52MP0001293_anophthalmia1.02219297
53MP0001145_abnormal_male_reproductive1.00037772
54MP0004147_increased_porphyrin_level0.99024019
55MP0002160_abnormal_reproductive_system0.98173007
56MP0005395_other_phenotype0.96974208
57MP0002086_abnormal_extraembryonic_tissu0.96694953
58MP0002095_abnormal_skin_pigmentation0.94591305
59MP0002429_abnormal_blood_cell0.92735328
60MP0000358_abnormal_cell_content/0.91837071
61MP0004133_heterotaxia0.90755789
62MP0004197_abnormal_fetal_growth/weight/0.89660971
63MP0003122_maternal_imprinting0.88402895
64MP0001929_abnormal_gametogenesis0.87500046
65MP0003567_abnormal_fetal_cardiomyocyte0.87204909
66MP0002751_abnormal_autonomic_nervous0.87068676
67MP0003937_abnormal_limbs/digits/tail_de0.86554123
68MP0000647_abnormal_sebaceous_gland0.85049236
69MP0000858_altered_metastatic_potential0.83855821
70MP0002233_abnormal_nose_morphology0.83563728
71MP0000653_abnormal_sex_gland0.83343901
72MP0002697_abnormal_eye_size0.83195401
73MP0010352_gastrointestinal_tract_polyps0.83047040
74MP0002877_abnormal_melanocyte_morpholog0.82545088
75MP0001545_abnormal_hematopoietic_system0.82037877
76MP0005397_hematopoietic_system_phenotyp0.82037877
77MP0000716_abnormal_immune_system0.81276444
78MP0005075_abnormal_melanosome_morpholog0.80625672
79MP0000372_irregular_coat_pigmentation0.80009711
80MP0003890_abnormal_embryonic-extraembry0.77904241
81MP0003186_abnormal_redox_activity0.77360705
82MP0005671_abnormal_response_to0.77357912
83MP0000049_abnormal_middle_ear0.76759819
84MP0005389_reproductive_system_phenotype0.76591722
85MP0009703_decreased_birth_body0.75141993
86MP0000465_gastrointestinal_hemorrhage0.74976733
87MP0005384_cellular_phenotype0.74446318
88MP0002111_abnormal_tail_morphology0.73973221
89MP0008995_early_reproductive_senescence0.73787240
90MP0001119_abnormal_female_reproductive0.73250520
91MP0002177_abnormal_outer_ear0.72333116
92MP0005174_abnormal_tail_pigmentation0.71612546
93MP0006036_abnormal_mitochondrial_physio0.71114911
94MP0002163_abnormal_gland_morphology0.71018960
95MP0008789_abnormal_olfactory_epithelium0.70539722
96MP0002420_abnormal_adaptive_immunity0.70162357
97MP0003698_abnormal_male_reproductive0.69587661
98MP0000015_abnormal_ear_pigmentation0.68192184
99MP0000631_abnormal_neuroendocrine_gland0.67848102
100MP0001819_abnormal_immune_cell0.67310720
101MP0005253_abnormal_eye_physiology0.67240318
102MP0005408_hypopigmentation0.65775859
103MP0002102_abnormal_ear_morphology0.65272453
104MP0009697_abnormal_copulation0.64583097
105MP0001905_abnormal_dopamine_level0.64264308
106MP0003755_abnormal_palate_morphology0.64144106
107MP0001800_abnormal_humoral_immune0.63188652
108MP0005501_abnormal_skin_physiology0.62227231
109MP0001764_abnormal_homeostasis0.61662070
110MP0002161_abnormal_fertility/fecundity0.61050333
111MP0001919_abnormal_reproductive_system0.60944004
112MP0003699_abnormal_female_reproductive0.60715354
113MP0006035_abnormal_mitochondrial_morpho0.60584464
114MP0005391_vision/eye_phenotype0.59715070
115MP0005621_abnormal_cell_physiology0.59382991
116MP0000516_abnormal_urinary_system0.58484419
117MP0005367_renal/urinary_system_phenotyp0.58484419
118MP0002405_respiratory_system_inflammati0.57216433
119MP0002452_abnormal_antigen_presenting0.57124373
120MP0001286_abnormal_eye_development0.56865203
121MP0009250_abnormal_appendicular_skeleto0.56392035
122MP0000537_abnormal_urethra_morphology0.55644066
123MP0001835_abnormal_antigen_presentation0.55345684
124MP0005499_abnormal_olfactory_system0.55139359
125MP0005394_taste/olfaction_phenotype0.55139359
126MP0002277_abnormal_respiratory_mucosa0.54904975
127MP0001188_hyperpigmentation0.54866041
128MP0003136_yellow_coat_color0.54734649
129MP0005187_abnormal_penis_morphology0.54729581
130MP0002736_abnormal_nociception_after0.54715069
131MP0001727_abnormal_embryo_implantation0.54461081
132MP0003119_abnormal_digestive_system0.54172932

Predicted human phenotypes

RankGene SetZ-score
1Reticulocytopenia (HP:0001896)4.72093563
2Abnormality of cells of the erythroid lineage (HP:0012130)4.23410917
3Birth length less than 3rd percentile (HP:0003561)4.15667891
4Abnormal number of erythroid precursors (HP:0012131)3.93717550
5Cerebral hypomyelination (HP:0006808)3.70209811
6Breast hypoplasia (HP:0003187)3.52722987
7Chromsome breakage (HP:0040012)3.38792974
8Patellar aplasia (HP:0006443)3.18094730
9Macrocytic anemia (HP:0001972)3.16265695
10Chromosomal breakage induced by crosslinking agents (HP:0003221)3.14966398
11Meckel diverticulum (HP:0002245)3.11972568
12Colon cancer (HP:0003003)3.10728794
13Aplastic anemia (HP:0001915)3.09281898
14Carpal bone hypoplasia (HP:0001498)3.06547905
15Oral leukoplakia (HP:0002745)3.04069915
16Abnormality of the preputium (HP:0100587)3.03567810
17Volvulus (HP:0002580)3.03038891
18Pallor (HP:0000980)3.00859684
19Aplasia/Hypoplasia of the patella (HP:0006498)2.99470258
20Abnormality of the ileum (HP:0001549)2.97714647
21Acute encephalopathy (HP:0006846)2.97630874
22Aplasia/Hypoplasia of the sacrum (HP:0008517)2.94690091
23Abnormality of chromosome stability (HP:0003220)2.84470343
24Rough bone trabeculation (HP:0100670)2.77630869
25Hypoplasia of the capital femoral epiphysis (HP:0003090)2.74463419
26Selective tooth agenesis (HP:0001592)2.72343175
27Abnormality of the anterior horn cell (HP:0006802)2.72160332
28Degeneration of anterior horn cells (HP:0002398)2.72160332
2911 pairs of ribs (HP:0000878)2.69459276
30Aplasia/Hypoplasia of the uvula (HP:0010293)2.63726835
31Premature graying of hair (HP:0002216)2.58769803
32Increased serum pyruvate (HP:0003542)2.58338344
33Abnormality of glycolysis (HP:0004366)2.58338344
34Progressive macrocephaly (HP:0004481)2.57510683
35* Abnormal lung lobation (HP:0002101)2.53857489
36Absent thumb (HP:0009777)2.51531993
37Clubbing of toes (HP:0100760)2.48309145
38Abnormality of the carotid arteries (HP:0005344)2.47654261
39Abnormal number of incisors (HP:0011064)2.46324914
40Medulloblastoma (HP:0002885)2.46134434
41Duplicated collecting system (HP:0000081)2.45414804
42* Duodenal stenosis (HP:0100867)2.44113227
43* Small intestinal stenosis (HP:0012848)2.44113227
44Bone marrow hypocellularity (HP:0005528)2.41399305
45Agnosia (HP:0010524)2.39192962
46Abnormality of the renal collecting system (HP:0004742)2.38168402
47Methylmalonic acidemia (HP:0002912)2.36655262
48Microretrognathia (HP:0000308)2.36202950
49Abnormality of methionine metabolism (HP:0010901)2.34925349
50* Nephroblastoma (Wilms tumor) (HP:0002667)2.34585447
51Absent radius (HP:0003974)2.33481660
52Microvesicular hepatic steatosis (HP:0001414)2.32365499
53Horseshoe kidney (HP:0000085)2.30459921
54Cerebral edema (HP:0002181)2.30211072
55Triphalangeal thumb (HP:0001199)2.29962999
56Abnormality of the labia minora (HP:0012880)2.28823534
57Irregular epiphyses (HP:0010582)2.24724596
58* Sloping forehead (HP:0000340)2.24715765
59Type I transferrin isoform profile (HP:0003642)2.23753966
60* Embryonal renal neoplasm (HP:0011794)2.23666837
61* Myelodysplasia (HP:0002863)2.23108055
62Increased hepatocellular lipid droplets (HP:0006565)2.22813721
63Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.22419729
64Absent epiphyses (HP:0010577)2.22419729
65Hypoplasia of the pons (HP:0012110)2.21794858
66Abnormality of the pons (HP:0007361)2.21645455
67Hepatic necrosis (HP:0002605)2.21535124
68Mitochondrial inheritance (HP:0001427)2.19316483
69Hepatocellular necrosis (HP:0001404)2.14513047
70Aplasia involving forearm bones (HP:0009822)2.14260481
71Absent forearm bone (HP:0003953)2.14260481
72Renal Fanconi syndrome (HP:0001994)2.14069148
73Cellular immunodeficiency (HP:0005374)2.11643699
74Supernumerary spleens (HP:0009799)2.10509987
75Abnormal trabecular bone morphology (HP:0100671)2.10435850
76Atresia of the external auditory canal (HP:0000413)2.08974446
77Trismus (HP:0000211)2.08562772
78Glossoptosis (HP:0000162)2.07827163
79Increased CSF lactate (HP:0002490)2.06025916
80Neoplasm of the pancreas (HP:0002894)2.05255979
81Cortical dysplasia (HP:0002539)2.04714417
82Increased serum lactate (HP:0002151)2.04361516
83Lactic acidosis (HP:0003128)2.04279000
84Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.03022563
85Reduced antithrombin III activity (HP:0001976)2.01032018
86Optic nerve coloboma (HP:0000588)2.00988259
87Impulsivity (HP:0100710)2.00863643
88Acute necrotizing encephalopathy (HP:0006965)2.00710184
89CNS hypomyelination (HP:0003429)1.99662897
90Glioma (HP:0009733)1.99320056
91Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.98918154
92* Increased nuchal translucency (HP:0010880)1.98722163
93Methylmalonic aciduria (HP:0012120)1.98512480
94* Neoplasm of the colon (HP:0100273)1.97020956
95Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.96939295
96Abnormal protein N-linked glycosylation (HP:0012347)1.96939295
97Abnormal protein glycosylation (HP:0012346)1.96939295
98Abnormal glycosylation (HP:0012345)1.96939295
99Tracheoesophageal fistula (HP:0002575)1.96483378
100Ependymoma (HP:0002888)1.96398313
101Ectopic kidney (HP:0000086)1.96385726
102Pancytopenia (HP:0001876)1.95170468
103Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.95117119
104Decreased activity of mitochondrial respiratory chain (HP:0008972)1.95117119
105Abnormality of serum amino acid levels (HP:0003112)1.94714632
106Cleft eyelid (HP:0000625)1.93826420
107Rhabdomyosarcoma (HP:0002859)1.92435605
108Stenosis of the external auditory canal (HP:0000402)1.92429963
109Secondary amenorrhea (HP:0000869)1.92011979
110* Abnormality of the duodenum (HP:0002246)1.90951002
111Abnormality of alanine metabolism (HP:0010916)1.90832782
112Hyperalaninemia (HP:0003348)1.90832782
113Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.90832782
114Postnatal microcephaly (HP:0005484)1.90567368
115Abnormality of DNA repair (HP:0003254)1.90385268
116Increased intramyocellular lipid droplets (HP:0012240)1.90159498
117Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.89536594
118Multiple enchondromatosis (HP:0005701)1.89367577
119Abnormality of the umbilical cord (HP:0010881)1.88656949
120Squamous cell carcinoma (HP:0002860)1.87084452
121Abnormality of the heme biosynthetic pathway (HP:0010472)1.87081527
122Short thumb (HP:0009778)1.86954800
123Exercise intolerance (HP:0003546)1.86309133
124Thrombocytosis (HP:0001894)1.85811378
125Lymphoma (HP:0002665)1.85726821
126Neoplasm of the adrenal gland (HP:0100631)1.84611964
127IgM deficiency (HP:0002850)1.82650231
128Abnormal mitochondria in muscle tissue (HP:0008316)1.82491599
129Megaloblastic anemia (HP:0001889)1.80513252
130Abnormality of aspartate family amino acid metabolism (HP:0010899)1.80321443
131IgG deficiency (HP:0004315)1.79505800
132Basal cell carcinoma (HP:0002671)1.78640217
133Type 2 muscle fiber atrophy (HP:0003554)1.77741931
134Choanal atresia (HP:0000453)1.76882482
135Respiratory difficulties (HP:0002880)1.76791374
136Exertional dyspnea (HP:0002875)1.75235880
137Lipid accumulation in hepatocytes (HP:0006561)1.74544889
138Muscle fiber atrophy (HP:0100295)1.74534557
139Pancreatic islet-cell hyperplasia (HP:0004510)1.74350583
140Abnormality of the calcaneus (HP:0008364)1.73225490
141Single umbilical artery (HP:0001195)1.73076782
142Abnormality of the fetal cardiovascular system (HP:0010948)1.73076782
143* Cafe-au-lait spot (HP:0000957)1.72994384
144Abnormality of the astrocytes (HP:0100707)1.70678544

Predicted kinase interactions (KEA)

RankGene SetZ-score
1* BUB15.22365582
2WEE14.49898575
3CDC73.50239229
4EIF2AK13.46613837
5VRK23.10619708
6STK162.91956399
7TESK22.87063590
8BRSK22.83775035
9SRPK12.44023577
10NEK22.29294419
11NME22.28739456
12VRK12.23136813
13PLK42.21073925
14CCNB12.20204506
15TSSK62.19727700
16BRSK12.16096171
17TTK2.04115854
18TLK12.01391000
19ACVR1B1.98563410
20MKNK11.97139743
21EIF2AK31.94078934
22PLK11.93586352
23PBK1.92783400
24TAF11.91112014
25TRIM281.89184628
26NUAK11.86684831
27NEK11.73516183
28AURKB1.71583794
29PLK31.69286125
30AURKA1.48168737
31RPS6KA41.36882614
32TGFBR11.36151163
33CDK71.34769347
34PASK1.34294256
35ATR1.31453974
36MKNK21.29693942
37MAP3K81.29656203
38STK101.19571079
39TESK11.16147759
40CHEK21.14239208
41STK41.13586163
42DYRK31.12698769
43RPS6KB21.06629133
44BRAF1.05826283
45MST41.05606279
46CLK11.05511156
47PAK41.05187076
48LIMK11.03278213
49WNK31.02760954
50CDK80.99420943
51PIM20.94282201
52CHEK10.94151031
53KDR0.89849141
54BCKDK0.88450993
55EIF2AK20.86813867
56CDK40.82826214
57NME10.82162087
58PAK10.81517050
59CSNK1G10.78504194
60TNIK0.76136260
61MAP4K10.75876137
62ZAK0.73935570
63ERBB30.72775137
64PNCK0.72009548
65STK30.69580302
66UHMK10.68026492
67CSNK2A10.66045671
68RPS6KA50.64501872
69MELK0.63724835
70CSNK2A20.61195046
71ATM0.60877089
72SCYL20.57989864
73CSNK1G20.57360503
74DYRK20.57275306
75LRRK20.57125376
76CDK20.56814597
77BLK0.53960747
78CDK10.53882981
79ILK0.50982481
80BTK0.50831966
81CSNK1A1L0.50267335
82ALK0.49405320
83CDK190.48932382
84PIM10.48267631
85TEC0.47533990
86ZAP700.46263420
87PDK20.46111049
88CDK180.45102347
89DAPK10.44837964
90ERBB40.44083561
91CDK150.44055362
92MAP3K110.43956728
93STK390.43829023
94CDK11A0.43743714
95CDK140.42711872
96EPHA20.42665450
97PRKCI0.42296634
98FGFR10.40362635
99MAP3K120.38925788
100CSNK1G30.38026298
101EEF2K0.37421063
102YES10.37231798
103CDK30.36763238
104SMG10.35652823
105IRAK40.35547771
106MAP3K100.33997374
107CSF1R0.30798575
108MAP2K30.29711768
109LYN0.29587364
110MAPKAPK50.29262571
111TXK0.28885150
112BMPR1B0.28587064
113ARAF0.27675474
114CSNK1E0.27569778
115BCR0.27296188
116STK38L0.26586193
117PRKDC0.26518768
118TAOK20.24332903
119GRK60.23688136
120PLK20.23674256
121MARK30.23644662
122FLT30.22148618
123OXSR10.20243749
124MAPKAPK20.19958833
125CDK60.19256704
126MINK10.19181031
127GRK10.18746971
128SYK0.17774093
129BRD40.17765827

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.85780753
2Mismatch repair_Homo sapiens_hsa034304.22082343
3Proteasome_Homo sapiens_hsa030504.06460291
4Ribosome_Homo sapiens_hsa030103.91500422
5RNA polymerase_Homo sapiens_hsa030203.38114614
6Spliceosome_Homo sapiens_hsa030403.34083998
7Homologous recombination_Homo sapiens_hsa034403.23049189
8Base excision repair_Homo sapiens_hsa034103.22039549
9Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.18401802
10Nucleotide excision repair_Homo sapiens_hsa034203.03133786
11RNA transport_Homo sapiens_hsa030132.75948622
12* Cell cycle_Homo sapiens_hsa041102.70923635
13Pyrimidine metabolism_Homo sapiens_hsa002402.43393769
14Fanconi anemia pathway_Homo sapiens_hsa034602.20079984
15Non-homologous end-joining_Homo sapiens_hsa034502.12459494
16Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.00492813
17Basal transcription factors_Homo sapiens_hsa030221.98375907
18One carbon pool by folate_Homo sapiens_hsa006701.92872216
19RNA degradation_Homo sapiens_hsa030181.86419065
20Protein export_Homo sapiens_hsa030601.57587468
21mRNA surveillance pathway_Homo sapiens_hsa030151.51244897
22p53 signaling pathway_Homo sapiens_hsa041151.44272480
23Purine metabolism_Homo sapiens_hsa002301.38121526
24Propanoate metabolism_Homo sapiens_hsa006401.29615337
25Selenocompound metabolism_Homo sapiens_hsa004501.28423225
26Parkinsons disease_Homo sapiens_hsa050121.26900768
27Systemic lupus erythematosus_Homo sapiens_hsa053221.25300414
28Epstein-Barr virus infection_Homo sapiens_hsa051691.23755157
29Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.20898262
30Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.15441078
31Pyruvate metabolism_Homo sapiens_hsa006201.14851854
32Oxidative phosphorylation_Homo sapiens_hsa001901.14423352
33Oocyte meiosis_Homo sapiens_hsa041141.14134873
34Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.12729682
35Huntingtons disease_Homo sapiens_hsa050161.09202820
362-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.08548542
37Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.06474283
38Fatty acid elongation_Homo sapiens_hsa000621.03535698
39Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.93077949
40Primary immunodeficiency_Homo sapiens_hsa053400.88810612
41Viral carcinogenesis_Homo sapiens_hsa052030.88529923
42Antigen processing and presentation_Homo sapiens_hsa046120.84771575
43Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.84393870
44Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.83907415
45Steroid biosynthesis_Homo sapiens_hsa001000.81923466
46Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.78187576
47Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.78053426
48Herpes simplex infection_Homo sapiens_hsa051680.74800208
49Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.70468469
50Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.70079518
51Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.66733069
52Alcoholism_Homo sapiens_hsa050340.65047705
53Pentose phosphate pathway_Homo sapiens_hsa000300.64405384
54Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.64400772
55* HTLV-I infection_Homo sapiens_hsa051660.62919677
56Vitamin B6 metabolism_Homo sapiens_hsa007500.59604107
57Thyroid cancer_Homo sapiens_hsa052160.55534639
58Alzheimers disease_Homo sapiens_hsa050100.54525134
59Folate biosynthesis_Homo sapiens_hsa007900.52650979
60Sulfur metabolism_Homo sapiens_hsa009200.52292746
61Shigellosis_Homo sapiens_hsa051310.52114739
62Cysteine and methionine metabolism_Homo sapiens_hsa002700.48967168
63Cyanoamino acid metabolism_Homo sapiens_hsa004600.48151528
64Legionellosis_Homo sapiens_hsa051340.47134021
65N-Glycan biosynthesis_Homo sapiens_hsa005100.45530871
66Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.45182540
67Glutathione metabolism_Homo sapiens_hsa004800.43622336
68Biosynthesis of amino acids_Homo sapiens_hsa012300.40956302
69Apoptosis_Homo sapiens_hsa042100.40196995
70Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.39910337
71Sulfur relay system_Homo sapiens_hsa041220.39633255
72Transcriptional misregulation in cancer_Homo sapiens_hsa052020.37271920
73MicroRNAs in cancer_Homo sapiens_hsa052060.35689099
74Colorectal cancer_Homo sapiens_hsa052100.33803109
75Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.33555416
76Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.31158088
77Butanoate metabolism_Homo sapiens_hsa006500.29612575
78Small cell lung cancer_Homo sapiens_hsa052220.28639450
79Measles_Homo sapiens_hsa051620.28537256
80Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.28470760
81Hepatitis B_Homo sapiens_hsa051610.27823331
82SNARE interactions in vesicular transport_Homo sapiens_hsa041300.27672308
83Pentose and glucuronate interconversions_Homo sapiens_hsa000400.27244005
84Asthma_Homo sapiens_hsa053100.26266102
85Peroxisome_Homo sapiens_hsa041460.25953528
86Hematopoietic cell lineage_Homo sapiens_hsa046400.25729201
87Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.25491666
88Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.24680966
89Fatty acid metabolism_Homo sapiens_hsa012120.24426671
90Viral myocarditis_Homo sapiens_hsa054160.22920360
91Metabolic pathways_Homo sapiens_hsa011000.22157974
92Cardiac muscle contraction_Homo sapiens_hsa042600.21626176
93TGF-beta signaling pathway_Homo sapiens_hsa043500.21463885
94Intestinal immune network for IgA production_Homo sapiens_hsa046720.21397587
95Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.21159052
96Hippo signaling pathway_Homo sapiens_hsa043900.20720051
97Allograft rejection_Homo sapiens_hsa053300.20626693
98Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.20511078
99Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.20104291
100Arachidonic acid metabolism_Homo sapiens_hsa005900.18952604
101Lysine degradation_Homo sapiens_hsa003100.17277019
102Vitamin digestion and absorption_Homo sapiens_hsa049770.17242776
103NF-kappa B signaling pathway_Homo sapiens_hsa040640.17110293
104Drug metabolism - other enzymes_Homo sapiens_hsa009830.16957387
105Fructose and mannose metabolism_Homo sapiens_hsa000510.16942143
106Pathways in cancer_Homo sapiens_hsa052000.16810533
107Wnt signaling pathway_Homo sapiens_hsa043100.16579741
108Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.16215944
109Carbon metabolism_Homo sapiens_hsa012000.16181102
110Graft-versus-host disease_Homo sapiens_hsa053320.15921510
111Basal cell carcinoma_Homo sapiens_hsa052170.15691586
112Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.14261523
113Vibrio cholerae infection_Homo sapiens_hsa051100.13882818
114Hedgehog signaling pathway_Homo sapiens_hsa043400.13495523
115Arginine and proline metabolism_Homo sapiens_hsa003300.13383886
116Bladder cancer_Homo sapiens_hsa052190.13193282
117Phagosome_Homo sapiens_hsa041450.12878100
118Phototransduction_Homo sapiens_hsa047440.12355077
119Autoimmune thyroid disease_Homo sapiens_hsa053200.11482487
120Influenza A_Homo sapiens_hsa051640.10510818
121Tryptophan metabolism_Homo sapiens_hsa003800.09554148
122NOD-like receptor signaling pathway_Homo sapiens_hsa046210.09527103
123HIF-1 signaling pathway_Homo sapiens_hsa040660.08731063
124Fatty acid degradation_Homo sapiens_hsa000710.06133916
125Leukocyte transendothelial migration_Homo sapiens_hsa046700.06056561
126Regulation of autophagy_Homo sapiens_hsa041400.05604045
127RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.04271752
128beta-Alanine metabolism_Homo sapiens_hsa004100.04177166
129T cell receptor signaling pathway_Homo sapiens_hsa046600.04122271
130Tyrosine metabolism_Homo sapiens_hsa003500.02248179
131Nitrogen metabolism_Homo sapiens_hsa009100.02215900
132Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.02077204

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