BUD13

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA unwinding involved in DNA replication (GO:0006268)5.59792900
2mitotic chromosome condensation (GO:0007076)5.45695041
3DNA topological change (GO:0006265)5.20499895
4sister chromatid segregation (GO:0000819)4.95008447
5establishment of integrated proviral latency (GO:0075713)4.73834275
6mitotic sister chromatid cohesion (GO:0007064)4.50920713
7regulation of attachment of spindle microtubules to kinetochore (GO:0051988)4.30717499
8regulation of sister chromatid cohesion (GO:0007063)4.13993225
9proteasome assembly (GO:0043248)4.04942195
10negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.82609950
11establishment of viral latency (GO:0019043)3.80940754
12double-strand break repair via nonhomologous end joining (GO:0006303)3.80180260
13non-recombinational repair (GO:0000726)3.80180260
14membrane disassembly (GO:0030397)3.80071504
15nuclear envelope disassembly (GO:0051081)3.80071504
16DNA replication checkpoint (GO:0000076)3.79641821
17mitotic metaphase plate congression (GO:0007080)3.78360673
18regulation of chromosome segregation (GO:0051983)3.68590448
19regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.67376656
20negative regulation of mRNA processing (GO:0050686)3.63297512
21positive regulation of chromosome segregation (GO:0051984)3.62637495
22chromosome segregation (GO:0007059)3.58456959
23regulation of double-strand break repair via homologous recombination (GO:0010569)3.56380823
24DNA replication initiation (GO:0006270)3.53580270
25negative regulation of chromosome segregation (GO:0051985)3.52534157
26mitotic spindle checkpoint (GO:0071174)3.51828200
27regulation of nuclear cell cycle DNA replication (GO:0033262)3.51000568
28negative regulation of mRNA metabolic process (GO:1903312)3.49401830
29negative regulation of mitotic sister chromatid separation (GO:2000816)3.47155357
30negative regulation of sister chromatid segregation (GO:0033046)3.47155357
31negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.47155357
32negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.47155357
33negative regulation of mitotic sister chromatid segregation (GO:0033048)3.47155357
34ribosome biogenesis (GO:0042254)3.45476828
35telomere maintenance via semi-conservative replication (GO:0032201)3.43770544
36IMP metabolic process (GO:0046040)3.43158179
37regulation of helicase activity (GO:0051095)3.39872257
38DNA deamination (GO:0045006)3.38084009
39polyketide metabolic process (GO:0030638)3.37579017
40doxorubicin metabolic process (GO:0044598)3.37579017
41daunorubicin metabolic process (GO:0044597)3.37579017
42regulation of mitotic metaphase/anaphase transition (GO:0030071)3.36189526
43regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.36189526
44negative regulation of RNA splicing (GO:0033119)3.35501517
45mitotic spindle assembly checkpoint (GO:0007094)3.34215158
46CENP-A containing nucleosome assembly (GO:0034080)3.33814262
47regulation of DNA endoreduplication (GO:0032875)3.33418562
48regulation of sister chromatid segregation (GO:0033045)3.31272011
49regulation of mitotic sister chromatid separation (GO:0010965)3.31272011
50regulation of mitotic sister chromatid segregation (GO:0033047)3.31272011
51protein localization to kinetochore (GO:0034501)3.29755397
52telomere maintenance via recombination (GO:0000722)3.29661059
53termination of RNA polymerase I transcription (GO:0006363)3.28843039
54spindle assembly checkpoint (GO:0071173)3.27769421
55DNA replication-dependent nucleosome organization (GO:0034723)3.27622852
56DNA replication-dependent nucleosome assembly (GO:0006335)3.27622852
57kinetochore assembly (GO:0051382)3.26883785
58positive regulation of mitotic sister chromatid separation (GO:1901970)3.26811886
59positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.26811886
60positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.26811886
61regulation of centriole replication (GO:0046599)3.24922832
62chromosome condensation (GO:0030261)3.24916511
63regulation of histone H3-K9 methylation (GO:0051570)3.22987882
64base-excision repair (GO:0006284)3.22722658
65maturation of 5.8S rRNA (GO:0000460)3.22329897
66DNA strand elongation involved in DNA replication (GO:0006271)3.22282473
67chromatin remodeling at centromere (GO:0031055)3.21266966
68purine nucleobase biosynthetic process (GO:0009113)3.18400993
69V(D)J recombination (GO:0033151)3.17394014
70DNA strand elongation (GO:0022616)3.16714338
71negative regulation of DNA-dependent DNA replication (GO:2000104)3.14086687
72transcription from RNA polymerase I promoter (GO:0006360)3.13176685
73microtubule depolymerization (GO:0007019)3.13155281
74metaphase plate congression (GO:0051310)3.12993002
75kinetochore organization (GO:0051383)3.12856087
76nucleobase biosynthetic process (GO:0046112)3.11942762
77mismatch repair (GO:0006298)3.11430065
78telomere maintenance via telomere lengthening (GO:0010833)3.10827729
79DNA duplex unwinding (GO:0032508)3.09115474
80rRNA modification (GO:0000154)3.07735368
81DNA geometric change (GO:0032392)3.07269075
82protein localization to chromosome, centromeric region (GO:0071459)3.07259577
83DNA conformation change (GO:0071103)3.07195575
84somatic cell DNA recombination (GO:0016444)3.07175576
85somatic diversification of immune receptors via germline recombination within a single locus (GO:0003.07175576
86histone H2A acetylation (GO:0043968)3.06444932
87transcription elongation from RNA polymerase I promoter (GO:0006362)3.03608158
88translesion synthesis (GO:0019985)3.03431930
89protein K6-linked ubiquitination (GO:0085020)3.02018777
90formation of translation preinitiation complex (GO:0001731)3.01976432
91chromatin assembly or disassembly (GO:0006333)3.01915959
92mitotic recombination (GO:0006312)3.00630679
93termination of RNA polymerase III transcription (GO:0006386)2.96059535
94transcription elongation from RNA polymerase III promoter (GO:0006385)2.96059535
957-methylguanosine mRNA capping (GO:0006370)2.94447438
96regulation of RNA export from nucleus (GO:0046831)2.94136522
97postreplication repair (GO:0006301)2.93907193
98maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.93349302
99mitotic G2/M transition checkpoint (GO:0044818)2.93073141
100RNA capping (GO:0036260)2.92869858
1017-methylguanosine RNA capping (GO:0009452)2.92869858
102termination of RNA polymerase II transcription (GO:0006369)2.92773813
103transcription initiation from RNA polymerase I promoter (GO:0006361)2.90644134
104centriole assembly (GO:0098534)2.89914269
105DNA replication-independent nucleosome assembly (GO:0006336)2.89472665
106DNA replication-independent nucleosome organization (GO:0034724)2.89472665
107regulation of mitotic spindle checkpoint (GO:1903504)2.89374951
108regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.89374951
109replicative senescence (GO:0090399)2.86763528
110maturation of SSU-rRNA (GO:0030490)2.85692539
111ribonucleoprotein complex biogenesis (GO:0022613)2.83273019
112poly(A)+ mRNA export from nucleus (GO:0016973)2.82963857
113tRNA methylation (GO:0030488)2.81020756
114nuclear pore complex assembly (GO:0051292)2.80640860
115nuclear pore organization (GO:0006999)2.80424068
116negative regulation of telomere maintenance (GO:0032205)2.77845430
117DNA catabolic process, exonucleolytic (GO:0000738)2.76525237
118attachment of spindle microtubules to kinetochore (GO:0008608)2.75779429
119transcription-coupled nucleotide-excision repair (GO:0006283)2.75222409
120rRNA methylation (GO:0031167)2.72933156
121meiotic chromosome segregation (GO:0045132)2.72400785
122viral mRNA export from host cell nucleus (GO:0046784)2.71846306
123mitotic sister chromatid segregation (GO:0000070)2.70813857
124establishment of chromosome localization (GO:0051303)2.70322446
125intra-S DNA damage checkpoint (GO:0031573)2.69876040
126telomere maintenance (GO:0000723)2.68452617
127replication fork processing (GO:0031297)2.68360555
128DNA strand renaturation (GO:0000733)2.67568641
129regulation of spindle organization (GO:0090224)2.66832798
130histone exchange (GO:0043486)2.66607983
131protein localization to chromosome (GO:0034502)2.65838290
132negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)2.65619427
133negative regulation of DNA-templated transcription, elongation (GO:0032785)2.65619427
134telomere organization (GO:0032200)2.65605339
135pseudouridine synthesis (GO:0001522)2.65407318
136spliceosomal snRNP assembly (GO:0000387)2.65139582
137rRNA processing (GO:0006364)2.64356655
138nucleotide-excision repair, DNA gap filling (GO:0006297)2.62639756
139pore complex assembly (GO:0046931)2.60905048
140DNA-templated transcription, termination (GO:0006353)2.60400677
141rRNA metabolic process (GO:0016072)2.58938565
142IMP biosynthetic process (GO:0006188)2.58613825
143histone H4-K12 acetylation (GO:0043983)2.57938243
144spindle checkpoint (GO:0031577)2.55752509
145ribosome assembly (GO:0042255)2.52695857
146DNA-dependent DNA replication (GO:0006261)2.51716328
147regulation of mitotic spindle organization (GO:0060236)2.51606190
148DNA ligation (GO:0006266)2.51356864
149somatic hypermutation of immunoglobulin genes (GO:0016446)2.51285441
150somatic diversification of immune receptors via somatic mutation (GO:0002566)2.51285441
151telomere maintenance via telomerase (GO:0007004)2.51149412
152DNA replication (GO:0006260)2.50833694
153exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.49979772
154positive regulation of transcription elongation from RNA polymerase II promoter (GO:0032968)2.46338870
155DNA double-strand break processing (GO:0000729)2.45478483
156DNA synthesis involved in DNA repair (GO:0000731)2.45445317
157mitotic nuclear envelope disassembly (GO:0007077)2.45221074
158DNA-templated transcription, elongation (GO:0006354)2.44447226

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.02965654
2E2F4_17652178_ChIP-ChIP_JURKAT_Human3.58509029
3FOXM1_23109430_ChIP-Seq_U2OS_Human3.58003774
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.43960733
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.43198726
6TP63_19390658_ChIP-ChIP_HaCaT_Human3.29521045
7FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.27481868
8* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.94988050
9EST1_17652178_ChIP-ChIP_JURKAT_Human2.86307599
10CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.60218486
11NOTCH1_21737748_ChIP-Seq_TLL_Human2.56606206
12GABP_17652178_ChIP-ChIP_JURKAT_Human2.54250768
13ELF1_17652178_ChIP-ChIP_JURKAT_Human2.51327175
14NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.44427519
15* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.38291579
16ETS1_20019798_ChIP-Seq_JURKAT_Human2.33908614
17MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.31070753
18MYC_19079543_ChIP-ChIP_MESCs_Mouse2.31044594
19CREB1_15753290_ChIP-ChIP_HEK293T_Human2.29215983
20HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.28800006
21MYC_18358816_ChIP-ChIP_MESCs_Mouse2.26234097
22HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.22907759
23MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.15290253
24HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.15253881
25* VDR_23849224_ChIP-Seq_CD4+_Human2.14658773
26YY1_21170310_ChIP-Seq_MESCs_Mouse2.14421791
27* FOXP3_21729870_ChIP-Seq_TREG_Human2.05463624
28CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.04489610
29KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.02932410
30EGR1_19374776_ChIP-ChIP_THP-1_Human1.97694156
31MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.89780420
32YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.89214555
33NELFA_20434984_ChIP-Seq_ESCs_Mouse1.85159943
34* E2F1_21310950_ChIP-Seq_MCF-7_Human1.81307721
35E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.79799432
36MYC_22102868_ChIP-Seq_BL_Human1.77368325
37ELK1_19687146_ChIP-ChIP_HELA_Human1.73560764
38FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.70531430
39SRF_21415370_ChIP-Seq_HL-1_Mouse1.67359466
40* TTF2_22483619_ChIP-Seq_HELA_Human1.66312588
41XRN2_22483619_ChIP-Seq_HELA_Human1.64280764
42SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.64274290
43* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.59890205
44E2F1_18555785_ChIP-Seq_MESCs_Mouse1.50044200
45PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.48618939
46THAP11_20581084_ChIP-Seq_MESCs_Mouse1.48616210
47MYCN_18555785_ChIP-Seq_MESCs_Mouse1.47801625
48CIITA_25753668_ChIP-Seq_RAJI_Human1.44286708
49* NANOG_18555785_ChIP-Seq_MESCs_Mouse1.43034954
50HOXB4_20404135_ChIP-ChIP_EML_Mouse1.42340642
51POU5F1_16153702_ChIP-ChIP_HESCs_Human1.41533531
52CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.40915008
53PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.40421325
54* GABP_19822575_ChIP-Seq_HepG2_Human1.39034227
55ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.38581949
56FLI1_27457419_Chip-Seq_LIVER_Mouse1.37850446
57CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.37637314
58* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.37214856
59PCGF2_27294783_Chip-Seq_ESCs_Mouse1.37150251
60TFEB_21752829_ChIP-Seq_HELA_Human1.36414735
61AR_21909140_ChIP-Seq_LNCAP_Human1.35522246
62POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.33501263
63FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.32143433
64IRF8_21731497_ChIP-ChIP_J774_Mouse1.31554871
65BP1_19119308_ChIP-ChIP_Hs578T_Human1.29923064
66SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.29578808
67* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.28187687
68POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.27861658
69* DCP1A_22483619_ChIP-Seq_HELA_Human1.25668482
70IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.23960300
71IRF1_19129219_ChIP-ChIP_H3396_Human1.22772215
72EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.18503461
73ERG_20887958_ChIP-Seq_HPC-7_Mouse1.16669469
74RBPJ_22232070_ChIP-Seq_NCS_Mouse1.16581252
75SALL1_21062744_ChIP-ChIP_HESCs_Human1.15810337
76CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.15210201
77SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.14934991
78* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.13467681
79MYC_18940864_ChIP-ChIP_HL60_Human1.11349011
80NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.09580227
81KAP1_22055183_ChIP-Seq_ESCs_Mouse1.09534716
82PADI4_21655091_ChIP-ChIP_MCF-7_Human1.09053925
83* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.08092254
84SOX2_18555785_ChIP-Seq_MESCs_Mouse1.07282731
85CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.06641557
86TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.04063875
87KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.02922220
88KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.02922220
89KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.02922220
90* EWS_26573619_Chip-Seq_HEK293_Human1.02149492
91SUZ12_27294783_Chip-Seq_NPCs_Mouse0.99549404
92NFE2_27457419_Chip-Seq_LIVER_Mouse0.98902706
93NANOG_21062744_ChIP-ChIP_HESCs_Human0.98855735
94* SPI1_23547873_ChIP-Seq_NB4_Human0.98746093
95IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.98134477
96VDR_21846776_ChIP-Seq_THP-1_Human0.97039371
97CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.95569615
98BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.94413387
99KDM5A_27292631_Chip-Seq_BREAST_Human0.94356298
100KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.90867511
101GATA1_26923725_Chip-Seq_HPCs_Mouse0.89603886
102SOX17_20123909_ChIP-Seq_XEN_Mouse0.89356807
103SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.88376103
104GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.87862780
105CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.86224867
106ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.85183553
107* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.82371124
108STAT3_1855785_ChIP-Seq_MESCs_Mouse0.82028893
109BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.80992302
110CHD1_26751641_Chip-Seq_LNCaP_Human0.79251407
111SOX2_16153702_ChIP-ChIP_HESCs_Human0.78376067
112PCGF2_27294783_Chip-Seq_NPCs_Mouse0.77526136
113NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.76647153
114IGF1R_20145208_ChIP-Seq_DFB_Human0.76205772
115MYB_26560356_Chip-Seq_TH2_Human0.75700987
116* CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.75078739
117NANOG_16153702_ChIP-ChIP_HESCs_Human0.74729984
118SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.74151218
119IRF8_22096565_ChIP-ChIP_GC-B_Human0.74113948
120PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.73347431
121* CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.68554808
122STAT3_18555785_Chip-Seq_ESCs_Mouse0.65463530
123TCF3_18692474_ChIP-Seq_MESCs_Mouse0.65377807

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.19285370
2MP0008057_abnormal_DNA_replication3.89681722
3MP0003111_abnormal_nucleus_morphology3.74123024
4MP0010094_abnormal_chromosome_stability3.50105825
5MP0006292_abnormal_olfactory_placode3.46678127
6MP0008058_abnormal_DNA_repair3.35096940
7MP0003077_abnormal_cell_cycle2.98424067
8MP0000566_synostosis2.64428388
9MP0002396_abnormal_hematopoietic_system2.58595171
10MP0004957_abnormal_blastocyst_morpholog2.33275571
11MP0008877_abnormal_DNA_methylation2.28941371
12MP0008007_abnormal_cellular_replicative2.28416609
13MP0002277_abnormal_respiratory_mucosa2.13675161
14MP0003941_abnormal_skin_development2.09185088
15MP0003718_maternal_effect1.93433969
16MP0001188_hyperpigmentation1.90597953
17MP0008932_abnormal_embryonic_tissue1.86093975
18MP0001986_abnormal_taste_sensitivity1.83097916
19MP0003136_yellow_coat_color1.76365106
20MP0003787_abnormal_imprinting1.73535646
21MP0003786_premature_aging1.71713939
22MP0001697_abnormal_embryo_size1.69814351
23MP0002163_abnormal_gland_morphology1.67619938
24MP0003121_genomic_imprinting1.62555327
25MP0003878_abnormal_ear_physiology1.59882817
26MP0005377_hearing/vestibular/ear_phenot1.59882817
27MP0010352_gastrointestinal_tract_polyps1.59860755
28MP0003763_abnormal_thymus_physiology1.55897819
29MP0005257_abnormal_intraocular_pressure1.55521827
30MP0002080_prenatal_lethality1.55505894
31MP0002132_abnormal_respiratory_system1.55341347
32MP0005075_abnormal_melanosome_morpholog1.54531505
33MP0003123_paternal_imprinting1.51953386
34MP0000490_abnormal_crypts_of1.49459151
35MP0002088_abnormal_embryonic_growth/wei1.48002012
36MP0009697_abnormal_copulation1.46699223
37MP0002938_white_spotting1.40912187
38MP0008260_abnormal_autophagy1.40846598
39MP0006035_abnormal_mitochondrial_morpho1.39195579
40MP0009672_abnormal_birth_weight1.39149939
41MP0004381_abnormal_hair_follicle1.36610634
42MP0003221_abnormal_cardiomyocyte_apopto1.34730925
43MP0009333_abnormal_splenocyte_physiolog1.34386720
44MP0005671_abnormal_response_to1.33695364
45MP0000015_abnormal_ear_pigmentation1.33301204
46MP0002653_abnormal_ependyma_morphology1.31330399
47MP0008789_abnormal_olfactory_epithelium1.30474186
48MP0004197_abnormal_fetal_growth/weight/1.28018340
49MP0002877_abnormal_melanocyte_morpholog1.27774490
50MP0000350_abnormal_cell_proliferation1.27584925
51MP0002084_abnormal_developmental_patter1.19057186
52MP0002210_abnormal_sex_determination1.18914819
53MP0005174_abnormal_tail_pigmentation1.17507414
54MP0001919_abnormal_reproductive_system1.17122966
55MP0002638_abnormal_pupillary_reflex1.16685671
56MP0004185_abnormal_adipocyte_glucose1.16659538
57MP0005076_abnormal_cell_differentiation1.16299342
58MP0000678_abnormal_parathyroid_gland1.15384579
59MP0000358_abnormal_cell_content/1.13443565
60MP0000049_abnormal_middle_ear1.13097814
61MP0009278_abnormal_bone_marrow1.13071789
62MP0001119_abnormal_female_reproductive1.12593592
63MP0001835_abnormal_antigen_presentation1.12017514
64MP0002086_abnormal_extraembryonic_tissu1.10694556
65MP0003937_abnormal_limbs/digits/tail_de1.10517091
66MP0003938_abnormal_ear_development1.09715383
67MP0003656_abnormal_erythrocyte_physiolo1.09613601
68MP0002102_abnormal_ear_morphology1.09307968
69MP0002095_abnormal_skin_pigmentation1.07842053
70MP0000703_abnormal_thymus_morphology1.05570616
71MP0005379_endocrine/exocrine_gland_phen1.03116860
72MP0005171_absent_coat_pigmentation1.02729231
73MP0005645_abnormal_hypothalamus_physiol1.02602103
74MP0000313_abnormal_cell_death1.00855527
75MP0002398_abnormal_bone_marrow1.00780093
76MP0001727_abnormal_embryo_implantation0.99176738
77MP0005389_reproductive_system_phenotype0.99019254
78MP0009785_altered_susceptibility_to0.97574796
79MP0001800_abnormal_humoral_immune0.97099498
80MP0003315_abnormal_perineum_morphology0.95441217
81MP0000516_abnormal_urinary_system0.95311202
82MP0005367_renal/urinary_system_phenotyp0.95311202
83MP0003699_abnormal_female_reproductive0.91499535
84MP0002722_abnormal_immune_system0.89482819
85MP0002085_abnormal_embryonic_tissue0.88500359
86MP0004808_abnormal_hematopoietic_stem0.88480386
87MP0001672_abnormal_embryogenesis/_devel0.87921139
88MP0005380_embryogenesis_phenotype0.87921139
89MP0005451_abnormal_body_composition0.87859429
90MP0002234_abnormal_pharynx_morphology0.86640722
91MP0002254_reproductive_system_inflammat0.86309703
92MP0000689_abnormal_spleen_morphology0.85750917
93MP0002452_abnormal_antigen_presenting0.85612529
94MP0005384_cellular_phenotype0.83810531
95MP0004264_abnormal_extraembryonic_tissu0.83627216
96MP0009703_decreased_birth_body0.83013365
97MP0002723_abnormal_immune_serum0.82757592
98MP0000716_abnormal_immune_system0.82553643
99MP0002160_abnormal_reproductive_system0.82297375
100MP0003806_abnormal_nucleotide_metabolis0.81719383
101MP0002420_abnormal_adaptive_immunity0.81569555
102MP0001819_abnormal_immune_cell0.81352913
103MP0005395_other_phenotype0.80939149
104MP0002697_abnormal_eye_size0.80823065
105MP0000372_irregular_coat_pigmentation0.80675298
106MP0001293_anophthalmia0.80576108
107MP0010307_abnormal_tumor_latency0.79736763
108MP0002111_abnormal_tail_morphology0.79522206
109MP0005394_taste/olfaction_phenotype0.79413925
110MP0005499_abnormal_olfactory_system0.79413925
111MP0001186_pigmentation_phenotype0.79242704
112MP0008995_early_reproductive_senescence0.79195190
113MP0001853_heart_inflammation0.79108431
114MP0001145_abnormal_male_reproductive0.78990082
115MP0002148_abnormal_hypersensitivity_rea0.77786972
116MP0001730_embryonic_growth_arrest0.77438597
117MP0003943_abnormal_hepatobiliary_system0.76173290
118MP0001929_abnormal_gametogenesis0.76133235
119MP0002429_abnormal_blood_cell0.75574157
120MP0000653_abnormal_sex_gland0.75297238
121MP0003567_abnormal_fetal_cardiomyocyte0.74959034
122MP0005397_hematopoietic_system_phenotyp0.74440153
123MP0001545_abnormal_hematopoietic_system0.74440153
124MP0004133_heterotaxia0.74173630
125MP0008004_abnormal_stomach_pH0.72732644
126MP0002019_abnormal_tumor_incidence0.72169608
127MP0005621_abnormal_cell_physiology0.71949853
128MP0001286_abnormal_eye_development0.71795414
129MP0003890_abnormal_embryonic-extraembry0.70972704
130MP0000432_abnormal_head_morphology0.69491823
131MP0003984_embryonic_growth_retardation0.69077211
132MP0005501_abnormal_skin_physiology0.68315591
133MP0000858_altered_metastatic_potential0.68171647
134MP0002751_abnormal_autonomic_nervous0.67669089
135MP0001346_abnormal_lacrimal_gland0.67449251
136MP0002161_abnormal_fertility/fecundity0.67366370
137MP0010030_abnormal_orbit_morphology0.67303347
138MP0001764_abnormal_homeostasis0.67152559
139MP0003119_abnormal_digestive_system0.67023643
140MP0002092_abnormal_eye_morphology0.66728992
141MP0006036_abnormal_mitochondrial_physio0.65187282
142MP0001915_intracranial_hemorrhage0.64204887
143MP0003698_abnormal_male_reproductive0.63791450
144MP0003303_peritoneal_inflammation0.63353470
145MP0001881_abnormal_mammary_gland0.60628317

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)5.09376733
2Chromsome breakage (HP:0040012)4.82576878
3Volvulus (HP:0002580)3.79355148
4Birth length less than 3rd percentile (HP:0003561)3.69838040
5Cortical dysplasia (HP:0002539)3.68992574
6Abnormality of the preputium (HP:0100587)3.66329583
7Meckel diverticulum (HP:0002245)3.38712134
8Increased nuchal translucency (HP:0010880)3.27032978
9Aplasia/Hypoplasia of the uvula (HP:0010293)3.21425113
10Abnormality of the ileum (HP:0001549)3.19519227
11Abnormality of the renal collecting system (HP:0004742)3.18162468
12Patellar aplasia (HP:0006443)3.15524957
13Abnormality of chromosome stability (HP:0003220)3.09831239
14Duplicated collecting system (HP:0000081)3.05191024
15Aplasia/Hypoplasia of the patella (HP:0006498)2.91363448
16Combined immunodeficiency (HP:0005387)2.85407295
17Clubbing of toes (HP:0100760)2.84751684
18Cholecystitis (HP:0001082)2.84341213
19Abnormal gallbladder physiology (HP:0012438)2.84341213
20Embryonal neoplasm (HP:0002898)2.81217840
21Multiple enchondromatosis (HP:0005701)2.80001564
22Ectopic kidney (HP:0000086)2.75607082
23Cafe-au-lait spot (HP:0000957)2.74415379
24Parakeratosis (HP:0001036)2.65660695
25Prostate neoplasm (HP:0100787)2.63340622
26Pancreatic fibrosis (HP:0100732)2.62707159
27Impulsivity (HP:0100710)2.58648846
28Ependymoma (HP:0002888)2.52748862
29Cheilitis (HP:0100825)2.51199791
30Small intestinal stenosis (HP:0012848)2.50438611
31Duodenal stenosis (HP:0100867)2.50438611
32True hermaphroditism (HP:0010459)2.49703043
33Reticulocytopenia (HP:0001896)2.46233010
34Breast hypoplasia (HP:0003187)2.43003985
35Pancytopenia (HP:0001876)2.41808175
36Facial hemangioma (HP:0000329)2.37873597
37Aplasia involving forearm bones (HP:0009822)2.37463671
38Absent forearm bone (HP:0003953)2.37463671
39Abnormality of chromosome segregation (HP:0002916)2.34962778
40Absent radius (HP:0003974)2.34072228
41Adrenal hypoplasia (HP:0000835)2.33910955
42Bone marrow hypocellularity (HP:0005528)2.32380029
43Abnormality of glycolysis (HP:0004366)2.30093873
44Progressive muscle weakness (HP:0003323)2.29172628
45Choanal atresia (HP:0000453)2.25651610
46Myelodysplasia (HP:0002863)2.24957249
47Microvesicular hepatic steatosis (HP:0001414)2.24596528
48Septo-optic dysplasia (HP:0100842)2.23136995
49Triphalangeal thumb (HP:0001199)2.21087556
50Absent thumb (HP:0009777)2.19936998
51Abnormality of DNA repair (HP:0003254)2.16982424
52Prominent metopic ridge (HP:0005487)2.14672130
53Pancreatic cysts (HP:0001737)2.12612503
54Aplasia/Hypoplasia of the sacrum (HP:0008517)2.12610430
55Colon cancer (HP:0003003)2.12515866
56Sloping forehead (HP:0000340)2.08853708
57Progressive external ophthalmoplegia (HP:0000590)2.08080934
58Medulloblastoma (HP:0002885)2.07264986
59Nephroblastoma (Wilms tumor) (HP:0002667)2.07084208
60Abnormality of the duodenum (HP:0002246)2.06491913
61Premature ovarian failure (HP:0008209)2.06174958
62Abnormality of the carotid arteries (HP:0005344)2.06161813
63Abnormality of the labia minora (HP:0012880)2.05769290
64Absent eyebrow (HP:0002223)2.03390100
65Glioma (HP:0009733)2.03063456
66Arteriovenous malformation (HP:0100026)2.02886855
67Rhabdomyosarcoma (HP:0002859)2.02153665
68Increased serum pyruvate (HP:0003542)2.01620376
69Horseshoe kidney (HP:0000085)2.01387234
70Abnormal lung lobation (HP:0002101)2.00896803
71Abnormality of the metopic suture (HP:0005556)1.97881595
72Neoplasm of the adrenal cortex (HP:0100641)1.97870627
73Shoulder girdle muscle weakness (HP:0003547)1.97095484
74Supernumerary spleens (HP:0009799)1.96433063
75Abnormality of pyrimidine metabolism (HP:0004353)1.96020926
76Type 2 muscle fiber atrophy (HP:0003554)1.95958055
77Embryonal renal neoplasm (HP:0011794)1.94959234
78Premature graying of hair (HP:0002216)1.93740552
79Preaxial hand polydactyly (HP:0001177)1.93548777
80Pendular nystagmus (HP:0012043)1.93540118
81Unilateral renal agenesis (HP:0000122)1.93036304
82Cleft eyelid (HP:0000625)1.92207172
83Oligohydramnios (HP:0001562)1.91452596
84IgM deficiency (HP:0002850)1.90401806
85Tracheoesophageal fistula (HP:0002575)1.90029916
86Amaurosis fugax (HP:0100576)1.90014551
87Abnormality of the astrocytes (HP:0100707)1.89009661
88Astrocytoma (HP:0009592)1.89009661
89Abnormality of placental membranes (HP:0011409)1.88624941
90Amniotic constriction ring (HP:0009775)1.88624941
91Rough bone trabeculation (HP:0100670)1.88115602
92Heterotopia (HP:0002282)1.87193418
93Leukopenia (HP:0001882)1.85899217
94Abnormal number of incisors (HP:0011064)1.84475275
95Abnormal trabecular bone morphology (HP:0100671)1.82721760
96Selective tooth agenesis (HP:0001592)1.82114653
97Abnormality of the columella (HP:0009929)1.81951825
98Optic nerve coloboma (HP:0000588)1.81868410
99Proximal placement of thumb (HP:0009623)1.81475989
100B lymphocytopenia (HP:0010976)1.80708072
101Neoplasm of the colon (HP:0100273)1.80346178
102Abnormality of the prostate (HP:0008775)1.79851648
103Aplastic anemia (HP:0001915)1.79605063
104Short thumb (HP:0009778)1.79289782
105Agnosia (HP:0010524)1.78341319
106Pelvic girdle muscle weakness (HP:0003749)1.78147019
107Carpal bone hypoplasia (HP:0001498)1.77479966
108Hypergonadotropic hypogonadism (HP:0000815)1.76859750
1093-Methylglutaconic aciduria (HP:0003535)1.76571650
110Stomach cancer (HP:0012126)1.76115106
111Type I transferrin isoform profile (HP:0003642)1.74934971
112Hypoplastic pelvis (HP:0008839)1.74178781
113Facial cleft (HP:0002006)1.73536791
114Lymphoma (HP:0002665)1.72889295
115Renal cortical cysts (HP:0000803)1.72819961
116Cellular immunodeficiency (HP:0005374)1.72294315
117Deep philtrum (HP:0002002)1.71854462
118Prolonged neonatal jaundice (HP:0006579)1.71774314
119Ureteral duplication (HP:0000073)1.71106407
120High anterior hairline (HP:0009890)1.71011044
121Osteomalacia (HP:0002749)1.70858785
122Muscle fiber atrophy (HP:0100295)1.70613155
123Granulocytopenia (HP:0001913)1.70124523
124Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.70100490
125Oral leukoplakia (HP:0002745)1.69342457
126Pulmonary fibrosis (HP:0002206)1.69223500
127Aganglionic megacolon (HP:0002251)1.68908144
128Intestinal atresia (HP:0011100)1.67561823
129Abnormality of lateral ventricle (HP:0030047)1.67346631
130Deviation of the thumb (HP:0009603)1.66701763
131Retrobulbar optic neuritis (HP:0100654)1.66400116
132Optic neuritis (HP:0100653)1.66400116
133Hypoplasia of the capital femoral epiphysis (HP:0003090)1.66116493
134Squamous cell carcinoma (HP:0002860)1.65641477
135Submucous cleft hard palate (HP:0000176)1.65056141
136Abnormality of the intervertebral disk (HP:0005108)1.63769095
137Absent eyelashes (HP:0000561)1.63270900
138Recurrent pneumonia (HP:0006532)1.63009936
139Subaortic stenosis (HP:0001682)1.62762104
140Abnormality of the left ventricular outflow tract (HP:0011103)1.62762104
141Abnormality of the parathyroid morphology (HP:0011766)1.61993334
142Prominent nose (HP:0000448)1.60278119
143Cerebral hypomyelination (HP:0006808)1.59478163
144Clitoromegaly (HP:0000057)1.59028543
145Hypoplastic iliac wings (HP:0002866)1.58503125
146Aplasia/Hypoplasia of the sternum (HP:0006714)1.58038743
147Aplasia/Hypoplasia involving the musculature (HP:0001460)1.57555600
148Recurrent abscess formation (HP:0002722)1.57324772
149Optic nerve hypoplasia (HP:0000609)1.56510311
150Mediastinal lymphadenopathy (HP:0100721)1.55930053
151Cystic hygroma (HP:0000476)1.55683768
152Severe combined immunodeficiency (HP:0004430)1.55469613
153Pancreatic islet-cell hyperplasia (HP:0004510)1.55396137
154Abnormality of the incisor (HP:0000676)1.54798697

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK23.65420356
2SRPK13.14397544
3STK163.10045569
4ZAK2.96555726
5PLK42.90704358
6BUB12.56623077
7EIF2AK12.42053305
8SIK32.38698282
9MKNK22.36533941
10NEK12.35524931
11SMG12.33377807
12AKT32.32970992
13IRAK32.22609537
14CDC72.21639040
15TXK2.18425872
16WEE12.00140103
17MKNK11.99251050
18TTK1.93547930
19EIF2AK21.84630340
20TAF11.83179099
21STK38L1.81045649
22TSSK61.79851548
23IRAK41.73379767
24MUSK1.72107825
25VRK11.71999087
26EIF2AK31.63859196
27CDK121.62111653
28BRSK21.59135659
29NUAK11.58575475
30WNK31.58491855
31CASK1.57355891
32TESK21.54332160
33BCKDK1.49387158
34CDK71.49381996
35PLK11.47366146
36CHEK21.47000915
37PLK31.46366611
38MAPK131.45326018
39EPHA21.43085852
40TRIM281.42708289
41ATR1.42223341
42TNIK1.37807671
43MAP3K101.35847184
44PASK1.35465585
45PRPF4B1.26459601
46ADRBK21.25933703
47EEF2K1.23927702
48CDK31.23030917
49CDK81.18196175
50MAP4K11.18103432
51YES11.17350847
52NEK21.15012436
53RPS6KB21.13132636
54AURKB1.10040640
55BRSK11.09986692
56TLK11.08162289
57MAP3K141.04444576
58MAP3K81.03543526
59NLK0.93915926
60* CHEK10.93533987
61PBK0.93451772
62LATS10.90720144
63STK40.87511129
64TEC0.87070212
65CDK60.82895543
66CDK90.82851654
67MAPKAPK30.79440630
68BRAF0.79382408
69STK30.77736055
70ATM0.76562148
71IKBKB0.76485792
72ICK0.76155159
73CLK10.74007120
74RPS6KA40.73241398
75BRD40.73098003
76AURKA0.71077026
77MARK30.70384722
78PIM10.69893826
79KSR10.68384191
80CHUK0.63824439
81CCNB10.63131072
82PIM20.62248827
83CDK20.61911685
84FGR0.61287582
85ALK0.61224273
86MAP2K30.60942244
87NME20.59869930
88TAOK20.59277567
89DYRK20.58098578
90JAK30.58012999
91IRAK10.55901125
92PAK40.55096762
93SIK20.52994945
94CSNK2A10.52096781
95IKBKE0.51726332
96RPS6KA50.51533017
97TRPM70.51507861
98DYRK30.50752188
99KIT0.49873491
100CDK40.49748568
101CDK10.49742623
102BTK0.47824979
103ERBB40.45724039
104STK100.45623548
105LYN0.45261641
106IRAK20.45055177
107CSNK2A20.45053109
108RAF10.44564996
109PNCK0.42170292
110TNK20.40979051
111TYK20.40443204
112STK240.39727425
113SGK20.39341245
114GRK70.38653062
115MST40.38621499
116MAP3K110.38611320
117BLK0.38323855
118AKT20.35718672
119MATK0.35431492
120MAPK140.34374174
121ACVR1B0.34110422
122MAPK110.33660148
123MAP2K60.33608315
124PRKDC0.33203550
125TAOK10.31929255
126PAK10.31397051
127MELK0.30541358
128PRKCI0.30455813
129MAP3K50.26328242
130MAPKAPK20.23837077
131CDK180.23117517
132DAPK10.22067724
133CDK140.21311998
134CDK150.20055862
135CDK11A0.19885166
136RPS6KA10.19556688
137FGFR10.19505792
138LRRK20.19087295

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.68214798
2Mismatch repair_Homo sapiens_hsa034303.58258584
3Homologous recombination_Homo sapiens_hsa034403.33035917
4RNA polymerase_Homo sapiens_hsa030203.20313659
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.19470507
6Fanconi anemia pathway_Homo sapiens_hsa034603.01703417
7Spliceosome_Homo sapiens_hsa030402.90061093
8Base excision repair_Homo sapiens_hsa034102.60388725
9Basal transcription factors_Homo sapiens_hsa030222.52370405
10RNA transport_Homo sapiens_hsa030132.45618414
11Nucleotide excision repair_Homo sapiens_hsa034202.39920613
12Cell cycle_Homo sapiens_hsa041102.28226100
13Pyrimidine metabolism_Homo sapiens_hsa002402.16079669
14Non-homologous end-joining_Homo sapiens_hsa034502.12416642
15Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.09341350
16Proteasome_Homo sapiens_hsa030502.07487587
17RNA degradation_Homo sapiens_hsa030182.03416725
18Ribosome_Homo sapiens_hsa030101.93061985
19One carbon pool by folate_Homo sapiens_hsa006701.87848957
20Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.66179427
21NF-kappa B signaling pathway_Homo sapiens_hsa040641.62754738
22Primary immunodeficiency_Homo sapiens_hsa053401.62731372
23mRNA surveillance pathway_Homo sapiens_hsa030151.58191761
24p53 signaling pathway_Homo sapiens_hsa041151.53385540
25Purine metabolism_Homo sapiens_hsa002301.46393355
26Herpes simplex infection_Homo sapiens_hsa051681.38428455
27Cysteine and methionine metabolism_Homo sapiens_hsa002701.28760137
28Intestinal immune network for IgA production_Homo sapiens_hsa046721.28617750
29Biosynthesis of amino acids_Homo sapiens_hsa012301.25388699
30Oocyte meiosis_Homo sapiens_hsa041141.20815844
312-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.20292276
32Epstein-Barr virus infection_Homo sapiens_hsa051691.16091462
33Measles_Homo sapiens_hsa051621.14005248
34Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.12853574
35Graft-versus-host disease_Homo sapiens_hsa053321.11368316
36Hematopoietic cell lineage_Homo sapiens_hsa046401.10567490
37Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.07930576
38RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.03407225
39Steroid biosynthesis_Homo sapiens_hsa001001.01844257
40Fatty acid elongation_Homo sapiens_hsa000621.01128980
41Autoimmune thyroid disease_Homo sapiens_hsa053201.00988701
42Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.98701611
43Vitamin B6 metabolism_Homo sapiens_hsa007500.97502354
44Carbon metabolism_Homo sapiens_hsa012000.93422486
45Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.91603083
46Allograft rejection_Homo sapiens_hsa053300.90754536
47Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.88765894
48Antigen processing and presentation_Homo sapiens_hsa046120.83722577
49Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.83710646
50Lysine degradation_Homo sapiens_hsa003100.80090761
51Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.79354625
52Transcriptional misregulation in cancer_Homo sapiens_hsa052020.79152967
53Pancreatic cancer_Homo sapiens_hsa052120.78702596
54Pentose phosphate pathway_Homo sapiens_hsa000300.77895518
55Regulation of autophagy_Homo sapiens_hsa041400.77211224
56Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.76199641
57Toll-like receptor signaling pathway_Homo sapiens_hsa046200.75193637
58Sulfur relay system_Homo sapiens_hsa041220.74916574
59NOD-like receptor signaling pathway_Homo sapiens_hsa046210.74824501
60Phototransduction_Homo sapiens_hsa047440.74603224
61Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.74492199
62Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.73296874
63Notch signaling pathway_Homo sapiens_hsa043300.72454690
64HTLV-I infection_Homo sapiens_hsa051660.70925693
65Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.70205559
66Chronic myeloid leukemia_Homo sapiens_hsa052200.70082974
67Influenza A_Homo sapiens_hsa051640.70042542
68Arachidonic acid metabolism_Homo sapiens_hsa005900.68785831
69Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.68369861
70Selenocompound metabolism_Homo sapiens_hsa004500.67920777
71Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.67911232
72Propanoate metabolism_Homo sapiens_hsa006400.67229997
73Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.66188424
74Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.66052889
75Shigellosis_Homo sapiens_hsa051310.66022018
76Asthma_Homo sapiens_hsa053100.65119267
77Basal cell carcinoma_Homo sapiens_hsa052170.65108003
78Viral carcinogenesis_Homo sapiens_hsa052030.64463030
79Systemic lupus erythematosus_Homo sapiens_hsa053220.64419059
80Non-small cell lung cancer_Homo sapiens_hsa052230.60892089
81Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.60037226
82Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.59654906
83Jak-STAT signaling pathway_Homo sapiens_hsa046300.59070842
84Leishmaniasis_Homo sapiens_hsa051400.58228313
85Apoptosis_Homo sapiens_hsa042100.57059116
86Legionellosis_Homo sapiens_hsa051340.55675559
87MicroRNAs in cancer_Homo sapiens_hsa052060.55641994
88Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.55579595
89Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.55521187
90Other glycan degradation_Homo sapiens_hsa005110.54903553
91Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.51519922
92Endometrial cancer_Homo sapiens_hsa052130.51496534
93Protein export_Homo sapiens_hsa030600.50790795
94Central carbon metabolism in cancer_Homo sapiens_hsa052300.49878227
95Glutathione metabolism_Homo sapiens_hsa004800.48685147
96Pyruvate metabolism_Homo sapiens_hsa006200.48005214
97Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.47528122
98Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.47178675
99T cell receptor signaling pathway_Homo sapiens_hsa046600.45831020
100Hepatitis B_Homo sapiens_hsa051610.44803984
101Small cell lung cancer_Homo sapiens_hsa052220.44401351
102Bladder cancer_Homo sapiens_hsa052190.43984956
103Sphingolipid metabolism_Homo sapiens_hsa006000.43054262
104Linoleic acid metabolism_Homo sapiens_hsa005910.40621758
105Prostate cancer_Homo sapiens_hsa052150.40257834
106B cell receptor signaling pathway_Homo sapiens_hsa046620.38023627
107Galactose metabolism_Homo sapiens_hsa000520.37489249
108Circadian rhythm_Homo sapiens_hsa047100.36959624
109N-Glycan biosynthesis_Homo sapiens_hsa005100.36651312
110Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.35884957
111Fructose and mannose metabolism_Homo sapiens_hsa000510.34873244
112Fatty acid metabolism_Homo sapiens_hsa012120.34798808
113Vitamin digestion and absorption_Homo sapiens_hsa049770.34591908
114Melanoma_Homo sapiens_hsa052180.34470788
115TNF signaling pathway_Homo sapiens_hsa046680.34117333
116Pathways in cancer_Homo sapiens_hsa052000.32934797
117Adherens junction_Homo sapiens_hsa045200.32591063
118Type I diabetes mellitus_Homo sapiens_hsa049400.32111878
119Ether lipid metabolism_Homo sapiens_hsa005650.30690331
120Rheumatoid arthritis_Homo sapiens_hsa053230.30617758
121TGF-beta signaling pathway_Homo sapiens_hsa043500.29276450
122Hepatitis C_Homo sapiens_hsa051600.29233093
123Drug metabolism - other enzymes_Homo sapiens_hsa009830.28411852
124alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.27195663
125Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.27147942
126Colorectal cancer_Homo sapiens_hsa052100.26957609
127Acute myeloid leukemia_Homo sapiens_hsa052210.26407258
128Tuberculosis_Homo sapiens_hsa051520.26336310
129Wnt signaling pathway_Homo sapiens_hsa043100.26195249
130Folate biosynthesis_Homo sapiens_hsa007900.26101400
131Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.24625647
132FoxO signaling pathway_Homo sapiens_hsa040680.24101950
133SNARE interactions in vesicular transport_Homo sapiens_hsa041300.23622975
134Hedgehog signaling pathway_Homo sapiens_hsa043400.23615431
135Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.23579827
136Thyroid cancer_Homo sapiens_hsa052160.22788376
137Alcoholism_Homo sapiens_hsa050340.21646816
138Cyanoamino acid metabolism_Homo sapiens_hsa004600.20761694
139Osteoclast differentiation_Homo sapiens_hsa043800.20601564
140Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.20321837
141Hippo signaling pathway_Homo sapiens_hsa043900.20051846
142Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.18774395

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