Rank | Gene Set | Z-score |
---|---|---|
1 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 6.45627846 |
2 | ATP synthesis coupled proton transport (GO:0015986) | 5.96939127 |
3 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.96939127 |
4 | proteasome assembly (GO:0043248) | 5.90616005 |
5 | ribosomal small subunit biogenesis (GO:0042274) | 5.80676840 |
6 | viral transcription (GO:0019083) | 5.48135988 |
7 | translational termination (GO:0006415) | 5.37973948 |
8 | maturation of SSU-rRNA (GO:0030490) | 5.20994429 |
9 | cotranslational protein targeting to membrane (GO:0006613) | 5.04029654 |
10 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 5.01711967 |
11 | protein targeting to ER (GO:0045047) | 4.96682172 |
12 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.92749734 |
13 | ribosomal small subunit assembly (GO:0000028) | 4.83212434 |
14 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.74877701 |
15 | protein localization to endoplasmic reticulum (GO:0070972) | 4.73296408 |
16 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 4.65532393 |
17 | negative regulation of ligase activity (GO:0051352) | 4.60107730 |
18 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 4.60107730 |
19 | regulation of cellular amino acid metabolic process (GO:0006521) | 4.56423284 |
20 | translational elongation (GO:0006414) | 4.51985143 |
21 | translational initiation (GO:0006413) | 4.50979018 |
22 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 4.47500631 |
23 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.47317875 |
24 | protein neddylation (GO:0045116) | 4.41151112 |
25 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 4.40021507 |
26 | termination of RNA polymerase III transcription (GO:0006386) | 4.40021507 |
27 | ribosomal large subunit biogenesis (GO:0042273) | 4.39134965 |
28 | chaperone-mediated protein transport (GO:0072321) | 4.37213916 |
29 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 4.36574688 |
30 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 4.35148919 |
31 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 4.33235275 |
32 | 7-methylguanosine mRNA capping (GO:0006370) | 4.32879667 |
33 | RNA capping (GO:0036260) | 4.29757834 |
34 | 7-methylguanosine RNA capping (GO:0009452) | 4.29757834 |
35 | cellular protein complex disassembly (GO:0043624) | 4.29244106 |
36 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 4.28360824 |
37 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 4.28360824 |
38 | viral life cycle (GO:0019058) | 4.27608542 |
39 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 4.23597410 |
40 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 4.23597410 |
41 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 4.23597410 |
42 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.22589110 |
43 | translation (GO:0006412) | 4.22340703 |
44 | establishment of integrated proviral latency (GO:0075713) | 4.19829647 |
45 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 4.15541727 |
46 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 4.15541727 |
47 | inner mitochondrial membrane organization (GO:0007007) | 4.14375814 |
48 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 4.10365539 |
49 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.09914422 |
50 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 4.07153193 |
51 | sequestering of actin monomers (GO:0042989) | 4.06441606 |
52 | respiratory electron transport chain (GO:0022904) | 4.05393071 |
53 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 4.00821833 |
54 | electron transport chain (GO:0022900) | 3.95961701 |
55 | regulation of mitochondrial translation (GO:0070129) | 3.91800980 |
56 | cullin deneddylation (GO:0010388) | 3.89703346 |
57 | positive regulation of ligase activity (GO:0051351) | 3.86945128 |
58 | formation of translation preinitiation complex (GO:0001731) | 3.84915795 |
59 | establishment of viral latency (GO:0019043) | 3.80580374 |
60 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.78186631 |
61 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.76851605 |
62 | ATP biosynthetic process (GO:0006754) | 3.76441895 |
63 | protein deneddylation (GO:0000338) | 3.76331541 |
64 | hydrogen ion transmembrane transport (GO:1902600) | 3.68013334 |
65 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.67124671 |
66 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.64595514 |
67 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 3.63366838 |
68 | spliceosomal snRNP assembly (GO:0000387) | 3.60821195 |
69 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.60560851 |
70 | NADH dehydrogenase complex assembly (GO:0010257) | 3.60560851 |
71 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.60560851 |
72 | protein complex disassembly (GO:0043241) | 3.58981488 |
73 | GTP biosynthetic process (GO:0006183) | 3.58943049 |
74 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 3.55960311 |
75 | spliceosomal complex assembly (GO:0000245) | 3.55779941 |
76 | rRNA processing (GO:0006364) | 3.50565281 |
77 | rRNA modification (GO:0000154) | 3.49618026 |
78 | establishment of protein localization to mitochondrion (GO:0072655) | 3.47971337 |
79 | regulation of cellular amine metabolic process (GO:0033238) | 3.47860743 |
80 | protein targeting to mitochondrion (GO:0006626) | 3.46730227 |
81 | regulation of ligase activity (GO:0051340) | 3.46294313 |
82 | protein-cofactor linkage (GO:0018065) | 3.43095730 |
83 | termination of RNA polymerase I transcription (GO:0006363) | 3.42192720 |
84 | macromolecular complex disassembly (GO:0032984) | 3.41923933 |
85 | DNA deamination (GO:0045006) | 3.40010840 |
86 | cellular component biogenesis (GO:0044085) | 3.39715088 |
87 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.36422804 |
88 | protein targeting to membrane (GO:0006612) | 3.35323433 |
89 | rRNA metabolic process (GO:0016072) | 3.33571115 |
90 | ribosome assembly (GO:0042255) | 3.31400340 |
91 | positive regulation of cell cycle arrest (GO:0071158) | 3.31001578 |
92 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 3.30118502 |
93 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 3.29083721 |
94 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 3.28909439 |
95 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.28141468 |
96 | intracellular protein transmembrane import (GO:0044743) | 3.27902541 |
97 | protein complex biogenesis (GO:0070271) | 3.27513832 |
98 | proton transport (GO:0015992) | 3.25474333 |
99 | transcription-coupled nucleotide-excision repair (GO:0006283) | 3.25139122 |
100 | oxidative phosphorylation (GO:0006119) | 3.23451612 |
101 | transcription from RNA polymerase I promoter (GO:0006360) | 3.22949155 |
102 | protein localization to mitochondrion (GO:0070585) | 3.21747223 |
103 | pseudouridine synthesis (GO:0001522) | 3.21718448 |
104 | UTP biosynthetic process (GO:0006228) | 3.21121236 |
105 | L-methionine biosynthetic process (GO:0071265) | 3.19832252 |
106 | amino acid salvage (GO:0043102) | 3.19832252 |
107 | L-methionine salvage (GO:0071267) | 3.19832252 |
108 | DNA damage response, detection of DNA damage (GO:0042769) | 3.19303352 |
109 | transcription elongation from RNA polymerase II promoter (GO:0006368) | 3.17601584 |
110 | hydrogen transport (GO:0006818) | 3.16934859 |
111 | mitochondrial transport (GO:0006839) | 3.15043840 |
112 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.13930385 |
113 | respiratory chain complex IV assembly (GO:0008535) | 3.11919873 |
114 | nucleoside triphosphate biosynthetic process (GO:0009142) | 3.11700081 |
115 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.10431014 |
116 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.08549712 |
117 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.06397805 |
118 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.06397805 |
119 | positive regulation of viral transcription (GO:0050434) | 3.05613884 |
Rank | Gene Set | Z-score |
---|---|---|
1 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 5.06133783 |
2 | * KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.94017459 |
3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.87487456 |
4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 4.45124257 |
5 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.27728361 |
6 | * JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.95015679 |
7 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.93204650 |
8 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.90658821 |
9 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.86769875 |
10 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.77884609 |
11 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.59311291 |
12 | * CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 3.33374760 |
13 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 3.25960925 |
14 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 3.13295184 |
15 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.99248740 |
16 | * HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.96781438 |
17 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.94484732 |
18 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.79011991 |
19 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.77458942 |
20 | * VDR_23849224_ChIP-Seq_CD4+_Human | 2.71225568 |
21 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.52077997 |
22 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.49832960 |
23 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.49710461 |
24 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.46199962 |
25 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.38067184 |
26 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.27528616 |
27 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.26504223 |
28 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.25931405 |
29 | * SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.12460547 |
30 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.12337266 |
31 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.06988176 |
32 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.06819087 |
33 | GABP_19822575_ChIP-Seq_HepG2_Human | 2.04941312 |
34 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.04235308 |
35 | TTF2_22483619_ChIP-Seq_HELA_Human | 2.02988098 |
36 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.86019611 |
37 | * FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.84115081 |
38 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.77520507 |
39 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.76933068 |
40 | * ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.76392296 |
41 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.74229574 |
42 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.73847029 |
43 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.70726310 |
44 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.66096397 |
45 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.63092520 |
46 | * MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.61172961 |
47 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.58171287 |
48 | * CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.57784415 |
49 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.47599969 |
50 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.41790289 |
51 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.38700373 |
52 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.37225329 |
53 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.36429152 |
54 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.36369112 |
55 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.34646613 |
56 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.31860544 |
57 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.31629757 |
58 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.31137659 |
59 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.27315615 |
60 | * ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.21977088 |
61 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.21948691 |
62 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.20349261 |
63 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.19703835 |
64 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 1.19480893 |
65 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.16408876 |
66 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.10182439 |
67 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.08691444 |
68 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.06719102 |
69 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.04481303 |
70 | * KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.04235682 |
71 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.00149784 |
72 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.99925578 |
73 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.96803692 |
74 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.93990595 |
75 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.93428239 |
76 | * CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.91223938 |
77 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.89967095 |
78 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.88893980 |
79 | * ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 0.86674516 |
80 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.86439477 |
81 | * CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.85867406 |
82 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.85368670 |
83 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.85083770 |
84 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.84808437 |
85 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 0.84037290 |
86 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 0.83828511 |
87 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.83771599 |
88 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.83729052 |
89 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 0.83582495 |
90 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.83349086 |
91 | * FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.82985291 |
92 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.82163084 |
93 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.81158034 |
94 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.80241862 |
95 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.79760198 |
96 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 0.77104433 |
97 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.77072483 |
98 | EWS_26573619_Chip-Seq_HEK293_Human | 0.77003961 |
99 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.76399700 |
100 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.75906556 |
101 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.74769475 |
102 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.73996918 |
103 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.73515719 |
104 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.71819710 |
105 | VDR_22108803_ChIP-Seq_LS180_Human | 0.71166414 |
106 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.68142295 |
107 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.67694921 |
108 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.67631896 |
109 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.67547070 |
110 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.65453776 |
111 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.65422389 |
112 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.64508121 |
113 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.64060570 |
114 | TRIM28_19339689_ChIP-ChIP_MESCs_Mouse | 0.63876904 |
115 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.63803985 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 4.27183730 |
2 | MP0004957_abnormal_blastocyst_morpholog | 3.96505122 |
3 | MP0009379_abnormal_foot_pigmentation | 3.86667418 |
4 | MP0003806_abnormal_nucleotide_metabolis | 3.35468943 |
5 | MP0001529_abnormal_vocalization | 3.33433327 |
6 | MP0008932_abnormal_embryonic_tissue | 3.10452970 |
7 | MP0003718_maternal_effect | 3.07330645 |
8 | MP0003077_abnormal_cell_cycle | 2.97190139 |
9 | MP0001905_abnormal_dopamine_level | 2.69419180 |
10 | MP0005408_hypopigmentation | 2.64340530 |
11 | MP0003186_abnormal_redox_activity | 2.54648740 |
12 | MP0008057_abnormal_DNA_replication | 2.54382528 |
13 | MP0010094_abnormal_chromosome_stability | 2.45830951 |
14 | MP0003111_abnormal_nucleus_morphology | 2.34871076 |
15 | MP0008058_abnormal_DNA_repair | 2.14824901 |
16 | MP0003136_yellow_coat_color | 2.11382657 |
17 | MP0009333_abnormal_splenocyte_physiolog | 2.07037254 |
18 | MP0001727_abnormal_embryo_implantation | 1.94730226 |
19 | MP0002653_abnormal_ependyma_morphology | 1.90946021 |
20 | MP0006036_abnormal_mitochondrial_physio | 1.86916017 |
21 | MP0004147_increased_porphyrin_level | 1.81681555 |
22 | MP0002736_abnormal_nociception_after | 1.79548723 |
23 | MP0010030_abnormal_orbit_morphology | 1.78345928 |
24 | MP0000920_abnormal_myelination | 1.77908319 |
25 | MP0001730_embryonic_growth_arrest | 1.70918442 |
26 | MP0008995_early_reproductive_senescence | 1.69650205 |
27 | MP0002938_white_spotting | 1.69582686 |
28 | MP0003123_paternal_imprinting | 1.66923621 |
29 | MP0003786_premature_aging | 1.66691554 |
30 | MP0001293_anophthalmia | 1.59634057 |
31 | MP0006035_abnormal_mitochondrial_morpho | 1.59041156 |
32 | MP0003315_abnormal_perineum_morphology | 1.56599423 |
33 | MP0001542_abnormal_bone_strength | 1.53684013 |
34 | MP0005423_abnormal_somatic_nervous | 1.52917282 |
35 | MP0002102_abnormal_ear_morphology | 1.47663479 |
36 | MP0005394_taste/olfaction_phenotype | 1.47625198 |
37 | MP0005499_abnormal_olfactory_system | 1.47625198 |
38 | MP0009697_abnormal_copulation | 1.39802652 |
39 | MP0008007_abnormal_cellular_replicative | 1.39591537 |
40 | MP0003656_abnormal_erythrocyte_physiolo | 1.30604197 |
41 | MP0002638_abnormal_pupillary_reflex | 1.29376790 |
42 | MP0005253_abnormal_eye_physiology | 1.29053599 |
43 | MP0001984_abnormal_olfaction | 1.26544961 |
44 | MP0008875_abnormal_xenobiotic_pharmacok | 1.26049185 |
45 | MP0009046_muscle_twitch | 1.25209072 |
46 | MP0002837_dystrophic_cardiac_calcinosis | 1.24705296 |
47 | MP0001661_extended_life_span | 1.23730355 |
48 | MP0003950_abnormal_plasma_membrane | 1.22734680 |
49 | MP0005451_abnormal_body_composition | 1.22475499 |
50 | MP0000358_abnormal_cell_content/ | 1.22324708 |
51 | MP0000372_irregular_coat_pigmentation | 1.19969537 |
52 | MP0003880_abnormal_central_pattern | 1.18023042 |
53 | MP0006054_spinal_hemorrhage | 1.17243070 |
54 | MP0000350_abnormal_cell_proliferation | 1.17234773 |
55 | MP0004142_abnormal_muscle_tone | 1.15809725 |
56 | MP0005410_abnormal_fertilization | 1.15393767 |
57 | MP0002163_abnormal_gland_morphology | 1.13103741 |
58 | MP0002095_abnormal_skin_pigmentation | 1.12426099 |
59 | MP0000647_abnormal_sebaceous_gland | 1.11498821 |
60 | MP0001968_abnormal_touch/_nociception | 1.11469011 |
61 | MP0005379_endocrine/exocrine_gland_phen | 1.09217988 |
62 | MP0004134_abnormal_chest_morphology | 1.08628258 |
63 | MP0000049_abnormal_middle_ear | 1.07989304 |
64 | MP0003011_delayed_dark_adaptation | 1.05661532 |
65 | MP0000462_abnormal_digestive_system | 1.05043581 |
66 | MP0003121_genomic_imprinting | 1.03608150 |
67 | MP0002090_abnormal_vision | 1.03274011 |
68 | MP0005551_abnormal_eye_electrophysiolog | 1.02892614 |
69 | MP0000313_abnormal_cell_death | 1.02823219 |
70 | MP0000631_abnormal_neuroendocrine_gland | 1.02815078 |
71 | MP0002822_catalepsy | 1.01278929 |
72 | MP0003937_abnormal_limbs/digits/tail_de | 1.00541316 |
73 | MP0001919_abnormal_reproductive_system | 1.00185818 |
74 | MP0001697_abnormal_embryo_size | 0.98821664 |
75 | MP0003221_abnormal_cardiomyocyte_apopto | 0.98783621 |
76 | MP0006082_CNS_inflammation | 0.98518242 |
77 | MP0009785_altered_susceptibility_to | 0.96747438 |
78 | MP0008872_abnormal_physiological_respon | 0.96740101 |
79 | MP0002080_prenatal_lethality | 0.96089664 |
80 | MP0008260_abnormal_autophagy | 0.96047494 |
81 | MP0005171_absent_coat_pigmentation | 0.95053301 |
82 | MP0005395_other_phenotype | 0.94988566 |
83 | MP0002234_abnormal_pharynx_morphology | 0.94119544 |
84 | MP0008789_abnormal_olfactory_epithelium | 0.93702514 |
85 | MP0004742_abnormal_vestibular_system | 0.93082865 |
86 | MP0005084_abnormal_gallbladder_morpholo | 0.91561204 |
87 | MP0005645_abnormal_hypothalamus_physiol | 0.91055530 |
88 | MP0001485_abnormal_pinna_reflex | 0.89681101 |
89 | MP0005391_vision/eye_phenotype | 0.87204342 |
90 | MP0002210_abnormal_sex_determination | 0.87007275 |
91 | MP0001929_abnormal_gametogenesis | 0.86936365 |
92 | MP0002295_abnormal_pulmonary_circulatio | 0.86041046 |
93 | MP0005389_reproductive_system_phenotype | 0.85628705 |
94 | MP0002272_abnormal_nervous_system | 0.84996128 |
95 | MP0002160_abnormal_reproductive_system | 0.84816927 |
96 | MP0002148_abnormal_hypersensitivity_rea | 0.84790412 |
97 | MP0002019_abnormal_tumor_incidence | 0.83779170 |
98 | MP0005636_abnormal_mineral_homeostasis | 0.82274906 |
99 | MP0001145_abnormal_male_reproductive | 0.81833971 |
100 | MP0005195_abnormal_posterior_eye | 0.81196148 |
101 | MP0002751_abnormal_autonomic_nervous | 0.81112132 |
102 | MP0003938_abnormal_ear_development | 0.80523160 |
103 | MP0005164_abnormal_response_to | 0.79283542 |
104 | MP0006276_abnormal_autonomic_nervous | 0.78490835 |
105 | MP0005075_abnormal_melanosome_morpholog | 0.78111503 |
106 | MP0009745_abnormal_behavioral_response | 0.77383362 |
107 | MP0000026_abnormal_inner_ear | 0.75169010 |
108 | MP0001286_abnormal_eye_development | 0.74855946 |
109 | MP0001764_abnormal_homeostasis | 0.73884971 |
110 | MP0000750_abnormal_muscle_regeneration | 0.73815523 |
111 | MP0002697_abnormal_eye_size | 0.73184971 |
112 | MP0001986_abnormal_taste_sensitivity | 0.73176157 |
113 | MP0003698_abnormal_male_reproductive | 0.72733023 |
114 | MP0005380_embryogenesis_phenotype | 0.72702689 |
115 | MP0001672_abnormal_embryogenesis/_devel | 0.72702689 |
116 | MP0005000_abnormal_immune_tolerance | 0.71653790 |
117 | MP0002752_abnormal_somatic_nervous | 0.71239339 |
118 | MP0000778_abnormal_nervous_system | 0.70613200 |
119 | MP0002233_abnormal_nose_morphology | 0.69431423 |
120 | MP0001853_heart_inflammation | 0.69292340 |
121 | MP0002085_abnormal_embryonic_tissue | 0.68657098 |
122 | MP0002132_abnormal_respiratory_system | 0.68024627 |
123 | MP0002282_abnormal_trachea_morphology | 0.67563986 |
124 | MP0005376_homeostasis/metabolism_phenot | 0.66918575 |
125 | MP0005409_darkened_coat_color | 0.66827641 |
126 | MP0000653_abnormal_sex_gland | 0.66489116 |
127 | MP0001324_abnormal_eye_pigmentation | 0.66159275 |
128 | MP0006072_abnormal_retinal_apoptosis | 0.65135897 |
129 | MP0005266_abnormal_metabolism | 0.64910325 |
130 | MP0000689_abnormal_spleen_morphology | 0.64447456 |
131 | MP0000490_abnormal_crypts_of | 0.64433626 |
132 | MP0004133_heterotaxia | 0.63797692 |
133 | MP0002277_abnormal_respiratory_mucosa | 0.62044870 |
134 | MP0002429_abnormal_blood_cell | 0.61186977 |
135 | MP0002722_abnormal_immune_system | 0.61173562 |
136 | MP0006292_abnormal_olfactory_placode | 0.60816223 |
137 | MP0000537_abnormal_urethra_morphology | 0.60698425 |
138 | MP0008877_abnormal_DNA_methylation | 0.60527077 |
139 | MP0005671_abnormal_response_to | 0.60189386 |
140 | MP0003984_embryonic_growth_retardation | 0.58757441 |
141 | MP0003724_increased_susceptibility_to | 0.56851924 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Acute necrotizing encephalopathy (HP:0006965) | 6.12147756 |
2 | Abnormal mitochondria in muscle tissue (HP:0008316) | 5.32050377 |
3 | Mitochondrial inheritance (HP:0001427) | 5.19109686 |
4 | Acute encephalopathy (HP:0006846) | 5.02563571 |
5 | Progressive macrocephaly (HP:0004481) | 4.91030133 |
6 | Increased hepatocellular lipid droplets (HP:0006565) | 4.88904985 |
7 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.85922449 |
8 | Abnormality of glycolysis (HP:0004366) | 4.50647951 |
9 | Increased serum pyruvate (HP:0003542) | 4.50647951 |
10 | Increased CSF lactate (HP:0002490) | 4.46140224 |
11 | Abnormal number of erythroid precursors (HP:0012131) | 4.36057332 |
12 | Lipid accumulation in hepatocytes (HP:0006561) | 4.33810443 |
13 | Hepatocellular necrosis (HP:0001404) | 4.17188908 |
14 | Cerebral hypomyelination (HP:0006808) | 4.17151688 |
15 | Renal Fanconi syndrome (HP:0001994) | 4.13512431 |
16 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 4.12486819 |
17 | 3-Methylglutaconic aciduria (HP:0003535) | 3.99633836 |
18 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.94214296 |
19 | Reticulocytopenia (HP:0001896) | 3.85505216 |
20 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 3.78477674 |
21 | Macrocytic anemia (HP:0001972) | 3.75513169 |
22 | Breast hypoplasia (HP:0003187) | 3.65145665 |
23 | Hepatic necrosis (HP:0002605) | 3.61564740 |
24 | Parakeratosis (HP:0001036) | 3.59168838 |
25 | Birth length less than 3rd percentile (HP:0003561) | 3.58345621 |
26 | Exertional dyspnea (HP:0002875) | 3.45004581 |
27 | Leukodystrophy (HP:0002415) | 3.43983313 |
28 | Cerebral edema (HP:0002181) | 3.42140146 |
29 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.22264658 |
30 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.22264658 |
31 | Increased intramyocellular lipid droplets (HP:0012240) | 3.19234606 |
32 | Increased serum lactate (HP:0002151) | 3.18748190 |
33 | Respiratory failure (HP:0002878) | 3.16844248 |
34 | Exercise intolerance (HP:0003546) | 3.10610639 |
35 | Pallor (HP:0000980) | 2.89412299 |
36 | Congenital ichthyosiform erythroderma (HP:0007431) | 2.88613859 |
37 | Respiratory difficulties (HP:0002880) | 2.81158000 |
38 | Optic disc pallor (HP:0000543) | 2.80933032 |
39 | Small epiphyses (HP:0010585) | 2.76485568 |
40 | Lactic acidosis (HP:0003128) | 2.75175488 |
41 | Carpal bone hypoplasia (HP:0001498) | 2.69662820 |
42 | Secondary amenorrhea (HP:0000869) | 2.64634615 |
43 | Abnormality of renal resorption (HP:0011038) | 2.63956402 |
44 | Microvesicular hepatic steatosis (HP:0001414) | 2.62470727 |
45 | Abnormality of the anterior horn cell (HP:0006802) | 2.58883485 |
46 | Degeneration of anterior horn cells (HP:0002398) | 2.58883485 |
47 | Increased muscle lipid content (HP:0009058) | 2.57907338 |
48 | Multiple enchondromatosis (HP:0005701) | 2.56603310 |
49 | Irregular epiphyses (HP:0010582) | 2.54657499 |
50 | Rough bone trabeculation (HP:0100670) | 2.53289983 |
51 | CNS hypomyelination (HP:0003429) | 2.50810066 |
52 | Medial flaring of the eyebrow (HP:0010747) | 2.50506269 |
53 | CNS demyelination (HP:0007305) | 2.45547968 |
54 | Delusions (HP:0000746) | 2.41417872 |
55 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.41029150 |
56 | Molar tooth sign on MRI (HP:0002419) | 2.40799845 |
57 | Abnormality of midbrain morphology (HP:0002418) | 2.40799845 |
58 | Generalized aminoaciduria (HP:0002909) | 2.32850860 |
59 | Pancreatic cysts (HP:0001737) | 2.31034512 |
60 | Postnatal microcephaly (HP:0005484) | 2.27296147 |
61 | Oral leukoplakia (HP:0002745) | 2.27001697 |
62 | Methylmalonic acidemia (HP:0002912) | 2.26917135 |
63 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 2.25864887 |
64 | Pancreatic fibrosis (HP:0100732) | 2.25802672 |
65 | Abnormality of alanine metabolism (HP:0010916) | 2.25663673 |
66 | Hyperalaninemia (HP:0003348) | 2.25663673 |
67 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.25663673 |
68 | Methylmalonic aciduria (HP:0012120) | 2.23418047 |
69 | Emotional lability (HP:0000712) | 2.22228374 |
70 | Spastic paraparesis (HP:0002313) | 2.15803545 |
71 | Glossoptosis (HP:0000162) | 2.13993229 |
72 | Adrenal hypoplasia (HP:0000835) | 2.13723322 |
73 | True hermaphroditism (HP:0010459) | 2.11994318 |
74 | Glycosuria (HP:0003076) | 2.11848134 |
75 | Abnormality of urine glucose concentration (HP:0011016) | 2.11848134 |
76 | Pancytopenia (HP:0001876) | 2.08961354 |
77 | Hyperphosphaturia (HP:0003109) | 2.07621636 |
78 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 2.05921856 |
79 | Concave nail (HP:0001598) | 2.05794051 |
80 | Abnormality of placental membranes (HP:0011409) | 2.04901869 |
81 | Amniotic constriction ring (HP:0009775) | 2.04901869 |
82 | Aplastic anemia (HP:0001915) | 2.02935023 |
83 | Congenital primary aphakia (HP:0007707) | 2.00229508 |
84 | Gait imbalance (HP:0002141) | 2.00031421 |
85 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 1.99915725 |
86 | Absent epiphyses (HP:0010577) | 1.99915725 |
87 | Poor head control (HP:0002421) | 1.98536379 |
88 | Trismus (HP:0000211) | 1.98531863 |
89 | Abnormal trabecular bone morphology (HP:0100671) | 1.97763697 |
90 | Sensory axonal neuropathy (HP:0003390) | 1.96944395 |
91 | Abnormality of the pons (HP:0007361) | 1.96820709 |
92 | Type I transferrin isoform profile (HP:0003642) | 1.96518979 |
93 | Nephrogenic diabetes insipidus (HP:0009806) | 1.93897276 |
94 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 1.93226639 |
95 | Blindness (HP:0000618) | 1.93026199 |
96 | Testicular atrophy (HP:0000029) | 1.92802433 |
97 | Abnormal ciliary motility (HP:0012262) | 1.92052415 |
98 | Lethargy (HP:0001254) | 1.91720798 |
99 | Abnormal pupillary function (HP:0007686) | 1.91696739 |
100 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.91478338 |
101 | Hypoplasia of the pons (HP:0012110) | 1.91356143 |
102 | Stenosis of the external auditory canal (HP:0000402) | 1.89677515 |
103 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.87595462 |
104 | Sclerocornea (HP:0000647) | 1.86673135 |
105 | Hepatosplenomegaly (HP:0001433) | 1.84802875 |
106 | Hyperglycinemia (HP:0002154) | 1.84710752 |
107 | Premature graying of hair (HP:0002216) | 1.83397617 |
108 | Seborrheic dermatitis (HP:0001051) | 1.79953516 |
109 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.79580785 |
110 | Nephronophthisis (HP:0000090) | 1.79531566 |
111 | X-linked dominant inheritance (HP:0001423) | 1.75435796 |
112 | Autoamputation (HP:0001218) | 1.74048263 |
113 | Microretrognathia (HP:0000308) | 1.72530457 |
114 | Abnormal hemoglobin (HP:0011902) | 1.72343109 |
115 | Hypoplastic pelvis (HP:0008839) | 1.72315693 |
116 | Abnormal autonomic nervous system physiology (HP:0012332) | 1.71027580 |
117 | Premature ovarian failure (HP:0008209) | 1.70803087 |
118 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.70005829 |
119 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.70005829 |
120 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 1.68350050 |
121 | Abnormality of the umbilical cord (HP:0010881) | 1.67560469 |
122 | Sparse eyelashes (HP:0000653) | 1.66735986 |
123 | Absent thumb (HP:0009777) | 1.66196443 |
124 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.64647448 |
125 | Abnormal protein glycosylation (HP:0012346) | 1.64647448 |
126 | Abnormal glycosylation (HP:0012345) | 1.64647448 |
127 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.64647448 |
128 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.64156251 |
129 | Dicarboxylic aciduria (HP:0003215) | 1.64156251 |
130 | Abnormal urine phosphate concentration (HP:0012599) | 1.63365695 |
131 | Abnormality of the fetal cardiovascular system (HP:0010948) | 1.62985080 |
132 | Abnormal umbilical cord blood vessels (HP:0011403) | 1.62985080 |
133 | Single umbilical artery (HP:0001195) | 1.62985080 |
134 | Abnormality of the labia minora (HP:0012880) | 1.62881696 |
135 | Congenital, generalized hypertrichosis (HP:0004540) | 1.62086628 |
136 | Irregular vertebral endplates (HP:0003301) | 1.61918174 |
137 | Erythroderma (HP:0001019) | 1.61732755 |
138 | Abnormality of serum amino acid levels (HP:0003112) | 1.61383592 |
139 | Colon cancer (HP:0003003) | 1.60463292 |
140 | Gliosis (HP:0002171) | 1.59592392 |
141 | Rhinitis (HP:0012384) | 1.59489040 |
142 | Upper limb muscle weakness (HP:0003484) | 1.58492620 |
143 | Poor suck (HP:0002033) | 1.58440819 |
Rank | Gene Set | Z-score |
---|---|---|
1 | VRK2 | 5.12964474 |
2 | BUB1 | 4.67587731 |
3 | NME2 | 3.68657414 |
4 | STK16 | 3.35351288 |
5 | WEE1 | 3.12166738 |
6 | PBK | 2.96973597 |
7 | EIF2AK1 | 2.87318490 |
8 | TESK2 | 2.75040915 |
9 | EIF2AK3 | 2.67776885 |
10 | SRPK1 | 2.54746729 |
11 | STK39 | 2.43810161 |
12 | MAP3K12 | 2.43430436 |
13 | NME1 | 2.39021785 |
14 | VRK1 | 2.32548058 |
15 | MST4 | 2.21683805 |
16 | NEK1 | 2.18252007 |
17 | LIMK1 | 2.10336851 |
18 | TLK1 | 1.90657301 |
19 | PLK4 | 1.84515848 |
20 | ARAF | 1.80926621 |
21 | PIM2 | 1.75112532 |
22 | DYRK2 | 1.71088422 |
23 | ACVR1B | 1.70994319 |
24 | KDR | 1.69502345 |
25 | PNCK | 1.61284318 |
26 | MAP4K2 | 1.56484594 |
27 | DYRK3 | 1.48930471 |
28 | TRIM28 | 1.43163939 |
29 | TESK1 | 1.39718813 |
30 | MKNK1 | 1.39370452 |
31 | BCR | 1.32526004 |
32 | BRSK2 | 1.32267664 |
33 | OXSR1 | 1.28369375 |
34 | ABL2 | 1.27066723 |
35 | MAP2K7 | 1.24958225 |
36 | CDC7 | 1.23424855 |
37 | EPHB2 | 1.17330990 |
38 | NUAK1 | 1.13668734 |
39 | AURKA | 1.13105638 |
40 | WNK4 | 1.09852271 |
41 | CSNK1G3 | 1.04501908 |
42 | TSSK6 | 1.03813948 |
43 | PLK3 | 1.03397005 |
44 | BRAF | 1.02466512 |
45 | EPHA2 | 1.02390072 |
46 | TXK | 0.98366386 |
47 | TNIK | 0.98232925 |
48 | PLK1 | 0.97384770 |
49 | RPS6KA5 | 0.94955345 |
50 | CDK19 | 0.93065014 |
51 | BMPR1B | 0.88183873 |
52 | PAK1 | 0.87432079 |
53 | AURKB | 0.86758946 |
54 | MAPKAPK5 | 0.83926952 |
55 | GRK1 | 0.83885419 |
56 | TAF1 | 0.82354448 |
57 | FGR | 0.80056841 |
58 | BLK | 0.78723727 |
59 | DAPK3 | 0.78270871 |
60 | RPS6KB2 | 0.78007731 |
61 | MKNK2 | 0.75396413 |
62 | MAP3K4 | 0.74161509 |
63 | LRRK2 | 0.72338958 |
64 | TTK | 0.71693329 |
65 | BRSK1 | 0.71625000 |
66 | CSNK2A1 | 0.70863307 |
67 | CSNK2A2 | 0.70463157 |
68 | MUSK | 0.68780621 |
69 | CSNK1G1 | 0.65928170 |
70 | ERBB3 | 0.64789370 |
71 | ATR | 0.63750075 |
72 | MET | 0.63732204 |
73 | PASK | 0.63232281 |
74 | CDK8 | 0.61367648 |
75 | PINK1 | 0.61210678 |
76 | PRKCG | 0.60416617 |
77 | CDK7 | 0.58616118 |
78 | UHMK1 | 0.57704953 |
79 | GRK7 | 0.57265923 |
80 | MAP3K8 | 0.57240346 |
81 | NEK2 | 0.56292999 |
82 | ILK | 0.55997267 |
83 | CSNK1A1L | 0.55652383 |
84 | MAPK15 | 0.54252927 |
85 | CDK14 | 0.53961994 |
86 | MYLK | 0.52581958 |
87 | DAPK1 | 0.50787499 |
88 | RPS6KA4 | 0.49971865 |
89 | MAP3K3 | 0.49845042 |
90 | CHEK2 | 0.49605731 |
91 | PLK2 | 0.49266522 |
92 | SCYL2 | 0.49220944 |
93 | IRAK4 | 0.48692471 |
94 | ZAK | 0.47560239 |
95 | EIF2AK2 | 0.46986559 |
96 | STK4 | 0.46880546 |
97 | TAOK2 | 0.44672007 |
98 | MINK1 | 0.44556695 |
99 | WNK3 | 0.44342029 |
100 | STK10 | 0.43826033 |
101 | CAMK2B | 0.42135431 |
102 | MAP3K11 | 0.41706196 |
103 | BCKDK | 0.40917388 |
104 | CASK | 0.40659756 |
105 | ADRBK2 | 0.40164240 |
106 | CDK11A | 0.40144061 |
107 | IRAK3 | 0.39966323 |
108 | CSNK1G2 | 0.38745264 |
109 | YES1 | 0.38660463 |
110 | MAPKAPK3 | 0.37815365 |
111 | CDK15 | 0.37768734 |
112 | INSRR | 0.37548262 |
113 | PAK4 | 0.36962583 |
114 | LYN | 0.36890781 |
115 | CDK18 | 0.36770194 |
116 | PDK2 | 0.36071269 |
117 | MOS | 0.35529332 |
118 | CCNB1 | 0.35507008 |
119 | ERBB4 | 0.35291047 |
120 | CHEK1 | 0.33971870 |
121 | CSNK1E | 0.33731966 |
122 | CAMK2G | 0.33618093 |
123 | ROCK2 | 0.32795422 |
124 | PRKCI | 0.32538028 |
125 | TGFBR1 | 0.32183105 |
126 | MELK | 0.31964326 |
127 | PKN1 | 0.30938926 |
128 | FES | 0.30232603 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Proteasome_Homo sapiens_hsa03050 | 5.50116551 |
2 | Ribosome_Homo sapiens_hsa03010 | 4.92893887 |
3 | RNA polymerase_Homo sapiens_hsa03020 | 4.02688057 |
4 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.87058001 |
5 | Parkinsons disease_Homo sapiens_hsa05012 | 3.26979509 |
6 | Protein export_Homo sapiens_hsa03060 | 3.18847353 |
7 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.67511887 |
8 | * Spliceosome_Homo sapiens_hsa03040 | 2.55932741 |
9 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.53776520 |
10 | Huntingtons disease_Homo sapiens_hsa05016 | 2.49714486 |
11 | DNA replication_Homo sapiens_hsa03030 | 2.45992727 |
12 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.31765225 |
13 | Alzheimers disease_Homo sapiens_hsa05010 | 2.29178628 |
14 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.06241416 |
15 | Mismatch repair_Homo sapiens_hsa03430 | 2.05836838 |
16 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.04640313 |
17 | Basal transcription factors_Homo sapiens_hsa03022 | 1.98488991 |
18 | RNA transport_Homo sapiens_hsa03013 | 1.96643602 |
19 | Homologous recombination_Homo sapiens_hsa03440 | 1.83583900 |
20 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.64761543 |
21 | Base excision repair_Homo sapiens_hsa03410 | 1.43666306 |
22 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.32818343 |
23 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.27661657 |
24 | RNA degradation_Homo sapiens_hsa03018 | 1.27264553 |
25 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.25153150 |
26 | Purine metabolism_Homo sapiens_hsa00230 | 1.19707989 |
27 | Cell cycle_Homo sapiens_hsa04110 | 1.18186611 |
28 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.17994501 |
29 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.17168321 |
30 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.15986343 |
31 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.15791912 |
32 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.15622622 |
33 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.07556443 |
34 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.03124731 |
35 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.03006812 |
36 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.98452664 |
37 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.96668956 |
38 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.89431676 |
39 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.88530239 |
40 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.87718691 |
41 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.87306951 |
42 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.85117797 |
43 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.85008878 |
44 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.80229502 |
45 | Metabolic pathways_Homo sapiens_hsa01100 | 0.72097470 |
46 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.70679066 |
47 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.70654579 |
48 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.70571958 |
49 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.68449560 |
50 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.66092093 |
51 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.64184710 |
52 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.63523181 |
53 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.63407774 |
54 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.63173385 |
55 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.59511091 |
56 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.59117164 |
57 | Sulfur relay system_Homo sapiens_hsa04122 | 0.58254985 |
58 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.57994030 |
59 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.57739986 |
60 | Phototransduction_Homo sapiens_hsa04744 | 0.57522056 |
61 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.57316945 |
62 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.55128474 |
63 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.54203730 |
64 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.52611403 |
65 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.51067001 |
66 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.50555492 |
67 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.50532222 |
68 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.49215400 |
69 | Phagosome_Homo sapiens_hsa04145 | 0.47947602 |
70 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.45033142 |
71 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.42837547 |
72 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.42669617 |
73 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.42163968 |
74 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.41860793 |
75 | Shigellosis_Homo sapiens_hsa05131 | 0.37892002 |
76 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.35132358 |
77 | Asthma_Homo sapiens_hsa05310 | 0.33975626 |
78 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.33646686 |
79 | Alcoholism_Homo sapiens_hsa05034 | 0.32747954 |
80 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.32578518 |
81 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.31994623 |
82 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.31327624 |
83 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.30138828 |
84 | Allograft rejection_Homo sapiens_hsa05330 | 0.30091201 |
85 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.29019921 |
86 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.28879377 |
87 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.24743786 |
88 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.23689383 |
89 | Malaria_Homo sapiens_hsa05144 | 0.23535063 |
90 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.22695502 |
91 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.22326039 |
92 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.22102646 |
93 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.21615087 |
94 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.21386690 |
95 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.21353211 |
96 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.20608435 |
97 | Carbon metabolism_Homo sapiens_hsa01200 | 0.20347584 |
98 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.19629078 |
99 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.19584252 |
100 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.19557476 |
101 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.19267257 |
102 | Nicotine addiction_Homo sapiens_hsa05033 | 0.18990893 |
103 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.17887320 |
104 | Peroxisome_Homo sapiens_hsa04146 | 0.17385110 |
105 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.17035399 |
106 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.16148003 |
107 | Other glycan degradation_Homo sapiens_hsa00511 | 0.15862407 |
108 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.15217582 |
109 | Histidine metabolism_Homo sapiens_hsa00340 | 0.14857350 |
110 | Legionellosis_Homo sapiens_hsa05134 | 0.14851719 |
111 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.14178251 |
112 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.13124959 |
113 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.12931715 |
114 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.12694775 |
115 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.11170936 |
116 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.10214352 |
117 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.09861390 |
118 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.08567469 |
119 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.07120934 |
120 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.07054226 |
121 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.06775865 |
122 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.05325146 |
123 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.04882326 |
124 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.03744425 |