BYSL

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Bystin is expressed as a 2-kb major transcript and a 3.6-kb minor transcript in SNG-M cells and in human trophoblastic teratocarcinoma HT-H cells. Protein binding assays determined that bystin binds directly to trophinin and tastin, and that binding is enhanced when cytokeratins 8 and 18 are present. Immunocytochemistry of HT-H cells showed that bystin colocalizes with trophinin, tastin, and the cytokeratins, suggesting that these molecules form a complex in trophectoderm cells at the time of implantation. Using immunohistochemistry it was determined that trophinin and bystin are found in the placenta from the sixth week of pregnancy. Both proteins were localized in the cytoplasm of the syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface. After week 10, the levels of trophinin, tastin, and bystin decreased and then disappeared from placental villi. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1viral transcription (GO:0019083)4.98334808
2translational termination (GO:0006415)4.88353439
3ribosomal large subunit biogenesis (GO:0042273)4.85188369
4DNA replication checkpoint (GO:0000076)4.70849145
5* maturation of SSU-rRNA (GO:0030490)4.65273707
6formation of translation preinitiation complex (GO:0001731)4.59986598
7DNA deamination (GO:0045006)4.58373489
8nucleobase biosynthetic process (GO:0046112)4.51757813
9establishment of integrated proviral latency (GO:0075713)4.46649597
10ribosomal small subunit assembly (GO:0000028)4.46454737
11translational elongation (GO:0006414)4.45593398
12translational initiation (GO:0006413)4.45398171
13spliceosomal snRNP assembly (GO:0000387)4.41911588
14ribosomal small subunit biogenesis (GO:0042274)4.40617835
15DNA strand elongation involved in DNA replication (GO:0006271)4.38377121
16DNA replication initiation (GO:0006270)4.37246884
17ribonucleoprotein complex biogenesis (GO:0022613)4.33981636
18mitotic chromosome condensation (GO:0007076)4.28413315
19purine nucleobase biosynthetic process (GO:0009113)4.24215577
20ribosome biogenesis (GO:0042254)4.23925983
21DNA strand elongation (GO:0022616)4.14873617
22telomere maintenance via semi-conservative replication (GO:0032201)4.08406398
23SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.07847495
24nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.07102556
25protein targeting to ER (GO:0045047)3.96369336
26cotranslational protein targeting to membrane (GO:0006613)3.96024058
27folic acid-containing compound biosynthetic process (GO:0009396)3.93368189
28mitotic sister chromatid segregation (GO:0000070)3.89725790
29cellular protein complex disassembly (GO:0043624)3.89617741
30ribosome assembly (GO:0042255)3.86268504
31mitotic metaphase plate congression (GO:0007080)3.84661303
32spliceosomal complex assembly (GO:0000245)3.83090107
33DNA unwinding involved in DNA replication (GO:0006268)3.82146646
34* rRNA processing (GO:0006364)3.81645042
35viral life cycle (GO:0019058)3.78976795
36proteasome assembly (GO:0043248)3.78397994
37establishment of protein localization to endoplasmic reticulum (GO:0072599)3.77246606
38mitotic nuclear envelope disassembly (GO:0007077)3.70549337
39* rRNA metabolic process (GO:0016072)3.70165499
40protein localization to endoplasmic reticulum (GO:0070972)3.69074690
41establishment of viral latency (GO:0019043)3.67179962
42protein localization to kinetochore (GO:0034501)3.66244239
43IMP biosynthetic process (GO:0006188)3.60806756
44translation (GO:0006412)3.56309424
45protein complex disassembly (GO:0043241)3.54383829
46telomere maintenance via recombination (GO:0000722)3.54244967
47regulation of translational fidelity (GO:0006450)3.54147481
48pseudouridine synthesis (GO:0001522)3.52723303
49protein maturation by protein folding (GO:0022417)3.52543420
50regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.50373691
51L-serine metabolic process (GO:0006563)3.49663699
52proline biosynthetic process (GO:0006561)3.49641315
53cullin deneddylation (GO:0010388)3.47709220
54rRNA modification (GO:0000154)3.46670889
55regulation of translational termination (GO:0006449)3.46033537
56chaperone-mediated protein transport (GO:0072321)3.43161265
57peptidyl-arginine omega-N-methylation (GO:0035247)3.42848299
58DNA replication-dependent nucleosome assembly (GO:0006335)3.42336222
59DNA replication-dependent nucleosome organization (GO:0034723)3.42336222
60sister chromatid segregation (GO:0000819)3.41175811
61macromolecular complex disassembly (GO:0032984)3.40430143
62membrane disassembly (GO:0030397)3.40114381
63nuclear envelope disassembly (GO:0051081)3.40114381
64nucleobase-containing small molecule interconversion (GO:0015949)3.39957569
65regulation of mitochondrial translation (GO:0070129)3.39306228
66transcription elongation from RNA polymerase III promoter (GO:0006385)3.37490317
67termination of RNA polymerase III transcription (GO:0006386)3.37490317
68spliceosomal tri-snRNP complex assembly (GO:0000244)3.32187976
69nuclear pore complex assembly (GO:0051292)3.31586833
70negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.31584466
71mitotic recombination (GO:0006312)3.30557610
72telomere maintenance via telomere lengthening (GO:0010833)3.30280688
73cellular component biogenesis (GO:0044085)3.29321065
74anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.29265408
75protein deneddylation (GO:0000338)3.28135415
76transcription-coupled nucleotide-excision repair (GO:0006283)3.24015489
77protein localization to chromosome, centromeric region (GO:0071459)3.22582296
78regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.21804416
79positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.21457154
80histone arginine methylation (GO:0034969)3.20436503
81folic acid metabolic process (GO:0046655)3.16487865
82nuclear-transcribed mRNA catabolic process (GO:0000956)3.15329540
83transcription from RNA polymerase I promoter (GO:0006360)3.14353346
84nucleotide-excision repair, DNA gap filling (GO:0006297)3.14147449
85negative regulation of translational initiation (GO:0045947)3.13916378
86heterochromatin organization (GO:0070828)3.13208343
87negative regulation of retinoic acid receptor signaling pathway (GO:0048387)3.12744234
88chromatin remodeling at centromere (GO:0031055)3.12066518
89metaphase plate congression (GO:0051310)3.11204576
90transcription from mitochondrial promoter (GO:0006390)3.08638233
91pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.07691078
92negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.07659396
93negative regulation of ligase activity (GO:0051352)3.07659396
94termination of RNA polymerase I transcription (GO:0006363)3.06235016
95CENP-A containing nucleosome assembly (GO:0034080)3.06178570
96regulation of mammary gland epithelial cell proliferation (GO:0033599)3.05255000
97protein complex localization (GO:0031503)3.04376753
98RNA splicing, via transesterification reactions (GO:0000375)3.02353190
99IMP metabolic process (GO:0046040)3.01760807
100intra-S DNA damage checkpoint (GO:0031573)3.01215350
101transcription elongation from RNA polymerase I promoter (GO:0006362)3.01065981
102RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)3.00662187
103mRNA splicing, via spliceosome (GO:0000398)3.00662187
104negative regulation of mRNA processing (GO:0050686)3.00266327
105RNA catabolic process (GO:0006401)2.98076394
106mRNA catabolic process (GO:0006402)2.97134380
1077-methylguanosine mRNA capping (GO:0006370)2.95333942
108tRNA methylation (GO:0030488)2.94719435
109nuclear pore organization (GO:0006999)2.94234186
110tRNA aminoacylation for protein translation (GO:0006418)2.93424866
111deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.91916235
112positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.91448592
113maturation of 5.8S rRNA (GO:0000460)2.90897826
114* ncRNA processing (GO:0034470)2.90512095
115mitotic nuclear envelope reassembly (GO:0007084)2.90371184
116nuclear envelope reassembly (GO:0031468)2.90371184
117negative regulation of RNA splicing (GO:0033119)2.88524762
118regulation of spindle organization (GO:0090224)2.87744701
119viral mRNA export from host cell nucleus (GO:0046784)2.87568802
120pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.87347662
121DNA damage response, detection of DNA damage (GO:0042769)2.86952781
122kinetochore organization (GO:0051383)2.86668489
123DNA replication-independent nucleosome assembly (GO:0006336)2.86349665
124DNA replication-independent nucleosome organization (GO:0034724)2.86349665
125RNA capping (GO:0036260)2.86254139
1267-methylguanosine RNA capping (GO:0009452)2.86254139
127kinetochore assembly (GO:0051382)2.86022778
128negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.85880106
129G1/S transition of mitotic cell cycle (GO:0000082)2.85815829
130rRNA transcription (GO:0009303)2.84633790
131regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.84389943
132amino acid activation (GO:0043038)2.83868631
133tRNA aminoacylation (GO:0043039)2.83868631
134pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.80464369
135mitochondrial RNA metabolic process (GO:0000959)2.79799850
136protein targeting to mitochondrion (GO:0006626)2.78467289
137cell cycle G1/S phase transition (GO:0044843)2.76921524
138peptidyl-arginine methylation (GO:0018216)2.76762062
139peptidyl-arginine N-methylation (GO:0035246)2.76762062

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.95298462
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.55097224
3* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.01916661
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.30497529
5* MYC_19079543_ChIP-ChIP_MESCs_Mouse3.28061195
6* KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.21545899
7ETS1_20019798_ChIP-Seq_JURKAT_Human3.19397439
8* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.15619449
9* MYC_18358816_ChIP-ChIP_MESCs_Mouse3.08223636
10E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.02964516
11EST1_17652178_ChIP-ChIP_JURKAT_Human3.01453681
12E2F4_17652178_ChIP-ChIP_JURKAT_Human2.98196400
13* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.94122866
14GABP_17652178_ChIP-ChIP_JURKAT_Human2.89472108
15* CREB1_15753290_ChIP-ChIP_HEK293T_Human2.82218131
16FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.78419864
17XRN2_22483619_ChIP-Seq_HELA_Human2.58125353
18HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.49500881
19NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.46180436
20MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.33709803
21NELFA_20434984_ChIP-Seq_ESCs_Mouse2.27531663
22VDR_23849224_ChIP-Seq_CD4+_Human2.19348273
23DCP1A_22483619_ChIP-Seq_HELA_Human2.19283128
24CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.17906454
25E2F1_18555785_ChIP-Seq_MESCs_Mouse2.10269169
26* GABP_19822575_ChIP-Seq_HepG2_Human2.02668337
27TTF2_22483619_ChIP-Seq_HELA_Human2.00296687
28THAP11_20581084_ChIP-Seq_MESCs_Mouse1.98948800
29FOXP3_21729870_ChIP-Seq_TREG_Human1.93348957
30MYCN_18555785_ChIP-Seq_MESCs_Mouse1.81678173
31NANOG_18555785_ChIP-Seq_MESCs_Mouse1.81524456
32HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.81008242
33SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.79433481
34MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.75828134
35YY1_21170310_ChIP-Seq_MESCs_Mouse1.74213055
36POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.72785232
37E2F1_21310950_ChIP-Seq_MCF-7_Human1.70035974
38MYC_22102868_ChIP-Seq_BL_Human1.64722927
39CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.64666854
40TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.62170774
41CIITA_25753668_ChIP-Seq_RAJI_Human1.61235140
42AR_21909140_ChIP-Seq_LNCAP_Human1.58999934
43ZFX_18555785_ChIP-Seq_MESCs_Mouse1.57583165
44SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.56415704
45* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.56375107
46ELF1_17652178_ChIP-ChIP_JURKAT_Human1.55133927
47ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.53540278
48* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.49596374
49PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.49315212
50KDM5A_27292631_Chip-Seq_BREAST_Human1.45911400
51YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.43496551
52* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.43096635
53POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.37833297
54STAT3_1855785_ChIP-Seq_MESCs_Mouse1.37045750
55* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.36226306
56ELK1_19687146_ChIP-ChIP_HELA_Human1.34959881
57EGR1_19374776_ChIP-ChIP_THP-1_Human1.32855002
58POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.32275798
59KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.31943613
60* SRF_21415370_ChIP-Seq_HL-1_Mouse1.31183039
61SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.30494132
62PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.29241026
63* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.27297722
64KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.22990889
65SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.21171605
66KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.20939283
67ESR1_15608294_ChIP-ChIP_MCF-7_Human1.19898591
68* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.19470945
69HOXB4_20404135_ChIP-ChIP_EML_Mouse1.12756736
70* NOTCH1_21737748_ChIP-Seq_TLL_Human1.12517358
71BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.12480105
72TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.11540296
73ERG_20887958_ChIP-Seq_HPC-7_Mouse1.11215624
74SOX2_18555785_ChIP-Seq_MESCs_Mouse1.09507191
75CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.08454660
76* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.07741335
77TP63_17297297_ChIP-ChIP_HaCaT_Human1.07560176
78TP63_19390658_ChIP-ChIP_HaCaT_Human1.07398980
79ELK1_22589737_ChIP-Seq_MCF10A_Human1.06899365
80RBPJ_22232070_ChIP-Seq_NCS_Mouse1.06604286
81ELK3_25401928_ChIP-Seq_HUVEC_Human1.06155915
82VDR_21846776_ChIP-Seq_THP-1_Human1.05934780
83E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.05925999
84TFEB_21752829_ChIP-Seq_HELA_Human1.04693769
85CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.04004922
86TET1_21451524_ChIP-Seq_MESCs_Mouse1.01332995
87DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.01059537
88PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.00970570
89PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.00908521
90TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.99702929
91KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.99298166
92KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.99298166
93KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.99298166
94TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.99124535
95* MYC_18940864_ChIP-ChIP_HL60_Human0.98993616
96SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.98878860
97OCT4_18692474_ChIP-Seq_MEFs_Mouse0.97545299
98* SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.97236795
99CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.95731594
100* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.95373240
101SRY_22984422_ChIP-ChIP_TESTIS_Rat0.95206961
102ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.95161031
103GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.94031957
104MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.93834044
105CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.93828962
106* TBX5_21415370_ChIP-Seq_HL-1_Mouse0.93771504
107SOX2_18692474_ChIP-Seq_MEFs_Mouse0.93698291
108CTCF_18555785_ChIP-Seq_MESCs_Mouse0.93504948
109FOXP1_21924763_ChIP-Seq_HESCs_Human0.92862001
110CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.92623943
111ZNF263_19887448_ChIP-Seq_K562_Human0.92368750
112HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.91244275
113* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.91017338
114TCF3_18692474_ChIP-Seq_MEFs_Mouse0.90897108
115NANOG_21062744_ChIP-ChIP_HESCs_Human0.88045666
116YY1_22570637_ChIP-Seq_MALME-3M_Human0.87676307
117PADI4_21655091_ChIP-ChIP_MCF-7_Human0.87283238

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.70566919
2MP0003111_abnormal_nucleus_morphology4.48155624
3MP0004957_abnormal_blastocyst_morpholog4.46472152
4MP0010094_abnormal_chromosome_stability3.96567555
5MP0003077_abnormal_cell_cycle3.86758028
6MP0008932_abnormal_embryonic_tissue3.21512710
7MP0008057_abnormal_DNA_replication3.08800635
8MP0008058_abnormal_DNA_repair2.90148775
9MP0001730_embryonic_growth_arrest2.57087532
10MP0003123_paternal_imprinting2.34942127
11MP0008007_abnormal_cellular_replicative2.26999759
12MP0000350_abnormal_cell_proliferation2.20202263
13MP0002877_abnormal_melanocyte_morpholog2.08943575
14MP0003786_premature_aging2.00467321
15MP0001697_abnormal_embryo_size1.99010382
16MP0001672_abnormal_embryogenesis/_devel1.97772956
17MP0005380_embryogenesis_phenotype1.97772956
18MP0008260_abnormal_autophagy1.97496749
19MP0010030_abnormal_orbit_morphology1.90278335
20MP0005451_abnormal_body_composition1.80654049
21* MP0002080_prenatal_lethality1.78739713
22MP0003984_embryonic_growth_retardation1.78598995
23MP0002088_abnormal_embryonic_growth/wei1.76576521
24MP0002085_abnormal_embryonic_tissue1.72966777
25MP0003718_maternal_effect1.72872003
26MP0010352_gastrointestinal_tract_polyps1.69535160
27MP0005501_abnormal_skin_physiology1.67682935
28MP0002653_abnormal_ependyma_morphology1.57807692
29MP0002396_abnormal_hematopoietic_system1.57774024
30MP0002084_abnormal_developmental_patter1.56705131
31MP0003567_abnormal_fetal_cardiomyocyte1.48985852
32MP0009697_abnormal_copulation1.47117101
33MP0000490_abnormal_crypts_of1.47020369
34MP0000313_abnormal_cell_death1.46249038
35MP0003119_abnormal_digestive_system1.44245977
36MP0001529_abnormal_vocalization1.44124183
37MP0010234_abnormal_vibrissa_follicle1.41978970
38MP0002086_abnormal_extraembryonic_tissu1.41875152
39MP0009333_abnormal_splenocyte_physiolog1.39964567
40MP0009053_abnormal_anal_canal1.39597351
41MP0002796_impaired_skin_barrier1.38902215
42MP0003806_abnormal_nucleotide_metabolis1.35685556
43MP0004197_abnormal_fetal_growth/weight/1.35545021
44MP0009379_abnormal_foot_pigmentation1.34772486
45MP0003941_abnormal_skin_development1.34363210
46MP0003315_abnormal_perineum_morphology1.34227984
47MP0000750_abnormal_muscle_regeneration1.32718720
48MP0002019_abnormal_tumor_incidence1.29858185
49MP0001293_anophthalmia1.29105607
50MP0010307_abnormal_tumor_latency1.26760303
51MP0000678_abnormal_parathyroid_gland1.25420844
52MP0004185_abnormal_adipocyte_glucose1.23078582
53MP0009672_abnormal_birth_weight1.22141678
54MP0001346_abnormal_lacrimal_gland1.22068140
55MP0005623_abnormal_meninges_morphology1.21289857
56MP0000358_abnormal_cell_content/1.18921535
57MP0003890_abnormal_embryonic-extraembry1.18484299
58MP0004133_heterotaxia1.17384393
59MP0006292_abnormal_olfactory_placode1.12744259
60MP0008877_abnormal_DNA_methylation1.12557504
61MP0001661_extended_life_span1.12544731
62MP0005076_abnormal_cell_differentiation1.10315856
63MP0003221_abnormal_cardiomyocyte_apopto1.08872581
64MP0002210_abnormal_sex_determination1.05517123
65MP0000428_abnormal_craniofacial_morphol1.05448474
66MP0005257_abnormal_intraocular_pressure1.05223673
67MP0000703_abnormal_thymus_morphology1.03873435
68MP0000537_abnormal_urethra_morphology1.02645700
69MP0001881_abnormal_mammary_gland0.98793104
70MP0002132_abnormal_respiratory_system0.98739315
71MP0000762_abnormal_tongue_morphology0.98511210
72MP0000049_abnormal_middle_ear0.98239121
73MP0001145_abnormal_male_reproductive0.96745774
74MP0004808_abnormal_hematopoietic_stem0.95263381
75MP0002163_abnormal_gland_morphology0.94890445
76MP0002160_abnormal_reproductive_system0.94622824
77MP0003763_abnormal_thymus_physiology0.93821834
78MP0005023_abnormal_wound_healing0.93703386
79MP0002111_abnormal_tail_morphology0.93425252
80MP0000627_abnormal_mammary_gland0.92072066
81MP0000733_abnormal_muscle_development0.89251919
82MP0001849_ear_inflammation0.88427570
83MP0003121_genomic_imprinting0.87752967
84MP0000858_altered_metastatic_potential0.87628872
85MP0001545_abnormal_hematopoietic_system0.86218603
86MP0005397_hematopoietic_system_phenotyp0.86218603
87MP0002697_abnormal_eye_size0.84773516
88MP0003186_abnormal_redox_activity0.80324299
89MP0002060_abnormal_skin_morphology0.79893622
90MP0002722_abnormal_immune_system0.79726221
91MP0005058_abnormal_lysosome_morphology0.78681060
92MP0003385_abnormal_body_wall0.78546709
93MP0005384_cellular_phenotype0.78251170
94MP0003937_abnormal_limbs/digits/tail_de0.77931238
95MP0004233_abnormal_muscle_weight0.77857109
96MP0002127_abnormal_cardiovascular_syste0.77831115
97MP0001929_abnormal_gametogenesis0.77591956
98MP0009703_decreased_birth_body0.77533923
99MP0003566_abnormal_cell_adhesion0.76865897
100MP0000653_abnormal_sex_gland0.76655726
101MP0004084_abnormal_cardiac_muscle0.76335169
102MP0002249_abnormal_larynx_morphology0.74385442
103MP0002102_abnormal_ear_morphology0.74057216
104MP0004272_abnormal_basement_membrane0.73568768
105MP0006035_abnormal_mitochondrial_morpho0.73071480
106MP0003646_muscle_fatigue0.72984637
107MP0001286_abnormal_eye_development0.72678826
108MP0005197_abnormal_uvea_morphology0.72224092
109MP0001348_abnormal_lacrimal_gland0.71886367
110MP0002398_abnormal_bone_marrow0.71733420
111MP0002234_abnormal_pharynx_morphology0.71516532
112MP0003699_abnormal_female_reproductive0.71015645
113MP0003656_abnormal_erythrocyte_physiolo0.70937283
114MP0008789_abnormal_olfactory_epithelium0.70462338
115MP0006036_abnormal_mitochondrial_physio0.70193742
116MP0004147_increased_porphyrin_level0.68719962
117MP0002089_abnormal_postnatal_growth/wei0.68347132
118MP0001216_abnormal_epidermal_layer0.68116416
119MP0001915_intracranial_hemorrhage0.67738854
120MP0000749_muscle_degeneration0.67696332
121MP0003453_abnormal_keratinocyte_physiol0.67379679
122MP0005389_reproductive_system_phenotype0.66907734
123MP0002269_muscular_atrophy0.66633043
124MP0003705_abnormal_hypodermis_morpholog0.66596706
125MP0000689_abnormal_spleen_morphology0.65656756
126MP0005621_abnormal_cell_physiology0.64908074
127MP0002932_abnormal_joint_morphology0.63998443
128MP0002114_abnormal_axial_skeleton0.62780147
129MP0002751_abnormal_autonomic_nervous0.62462519
130MP0003942_abnormal_urinary_system0.62244694
131MP0005330_cardiomyopathy0.61709262
132MP0001727_abnormal_embryo_implantation0.61525055
133MP0003755_abnormal_palate_morphology0.59626412
134MP0003935_abnormal_craniofacial_develop0.59046448

Predicted human phenotypes

RankGene SetZ-score
1Breast hypoplasia (HP:0003187)4.94528401
2Reticulocytopenia (HP:0001896)4.83706140
3Birth length less than 3rd percentile (HP:0003561)4.48096509
4Abnormality of cells of the erythroid lineage (HP:0012130)4.15435808
5Abnormal number of erythroid precursors (HP:0012131)3.88230697
6Macrocytic anemia (HP:0001972)3.77311274
7Cerebral hypomyelination (HP:0006808)3.66707898
8Aplasia/Hypoplasia of the patella (HP:0006498)3.44405411
9Carpal bone hypoplasia (HP:0001498)3.43793482
10Patellar aplasia (HP:0006443)3.40744152
11Trismus (HP:0000211)3.33774298
12Selective tooth agenesis (HP:0001592)3.25726213
13Oral leukoplakia (HP:0002745)3.25022606
14Pallor (HP:0000980)3.24265415
15Abnormality of glycolysis (HP:0004366)3.23674357
16Ragged-red muscle fibers (HP:0003200)3.18570060
17Aplasia/Hypoplasia of the sacrum (HP:0008517)3.15513207
18Abnormality of the anterior horn cell (HP:0006802)3.08484961
19Degeneration of anterior horn cells (HP:0002398)3.08484961
20Rough bone trabeculation (HP:0100670)3.05885980
21Progressive muscle weakness (HP:0003323)3.01957742
22Increased serum pyruvate (HP:0003542)3.01900848
23Impulsivity (HP:0100710)2.85434046
24Ependymoma (HP:0002888)2.82183963
25Multiple enchondromatosis (HP:0005701)2.80707949
26Secondary amenorrhea (HP:0000869)2.79267206
27Meckel diverticulum (HP:0002245)2.72298191
28Absent radius (HP:0003974)2.70975395
29Horseshoe kidney (HP:0000085)2.66712988
30Absent thumb (HP:0009777)2.66012172
31Abnormality of the ileum (HP:0001549)2.60027751
32Rhabdomyosarcoma (HP:0002859)2.59075848
33Premature ovarian failure (HP:0008209)2.56644169
34Colon cancer (HP:0003003)2.54786647
35Absent forearm bone (HP:0003953)2.50001191
36Aplasia involving forearm bones (HP:0009822)2.50001191
37Progressive external ophthalmoplegia (HP:0000590)2.49988321
38Abnormal number of incisors (HP:0011064)2.48059052
3911 pairs of ribs (HP:0000878)2.47835671
40Proximal placement of thumb (HP:0009623)2.46562582
41Cholecystitis (HP:0001082)2.45086723
42Abnormal gallbladder physiology (HP:0012438)2.45086723
43Abnormal mitochondria in muscle tissue (HP:0008316)2.43299065
44Microretrognathia (HP:0000308)2.42445679
45Long palpebral fissure (HP:0000637)2.41453543
46Abnormality of the preputium (HP:0100587)2.40557512
47Atresia of the external auditory canal (HP:0000413)2.39682568
48Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.39645782
49Medulloblastoma (HP:0002885)2.38071070
50Neoplasm of the pancreas (HP:0002894)2.37710314
51Entropion (HP:0000621)2.35503240
52Triphalangeal thumb (HP:0001199)2.34840600
53Abnormalities of placenta or umbilical cord (HP:0001194)2.34806868
54Deviation of the thumb (HP:0009603)2.34685298
55Cleft eyelid (HP:0000625)2.33694628
56Concave nail (HP:0001598)2.30930567
57Abnormality of the umbilical cord (HP:0010881)2.30151071
58Angiofibromas (HP:0010615)2.29016708
59Adenoma sebaceum (HP:0009720)2.29016708
60Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.28114050
61Testicular atrophy (HP:0000029)2.27694067
62Generalized amyotrophy (HP:0003700)2.26151071
63Aplastic anemia (HP:0001915)2.24088989
64Abnormality of the labia minora (HP:0012880)2.22597330
65Microvesicular hepatic steatosis (HP:0001414)2.20196532
66Abnormality of the distal phalanges of the toes (HP:0010182)2.18593921
67Type I transferrin isoform profile (HP:0003642)2.16106427
68Acute necrotizing encephalopathy (HP:0006965)2.15430568
69Shoulder girdle muscle weakness (HP:0003547)2.15057191
70Abnormality of chromosome stability (HP:0003220)2.14562954
71Basal cell carcinoma (HP:0002671)2.14435510
72Premature graying of hair (HP:0002216)2.11888931
73Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.10569848
74Decreased activity of mitochondrial respiratory chain (HP:0008972)2.10569848
75Increased serum lactate (HP:0002151)2.09385658
76Sparse eyelashes (HP:0000653)2.08248948
77Aplasia/Hypoplasia of the uvula (HP:0010293)2.07970386
78High anterior hairline (HP:0009890)2.06420696
79Increased intramyocellular lipid droplets (HP:0012240)2.06359248
80Hypergonadotropic hypogonadism (HP:0000815)2.06263677
81Abnormal trabecular bone morphology (HP:0100671)2.05877354
82Acute encephalopathy (HP:0006846)2.04823374
83Abnormality of reticulocytes (HP:0004312)2.04651953
84Exercise intolerance (HP:0003546)2.03301073
85Septate vagina (HP:0001153)2.00694666
86Neoplasm of striated muscle (HP:0009728)1.99777989
87Ureteral duplication (HP:0000073)1.99316241
88Achilles tendon contracture (HP:0001771)1.98742955
89Abnormality of abdominal situs (HP:0011620)1.98310644
90Abdominal situs inversus (HP:0003363)1.98310644
91Poikiloderma (HP:0001029)1.98197484
92Slender long bone (HP:0003100)1.96463663
93Tracheoesophageal fistula (HP:0002575)1.95477926
94Facial cleft (HP:0002006)1.95350751
95Chromsome breakage (HP:0040012)1.95230012
96Hypoplasia of the radius (HP:0002984)1.94347839
97Aplasia/hypoplasia of the humerus (HP:0006507)1.94281004
98Upper limb muscle weakness (HP:0003484)1.94115420
99Pancytopenia (HP:0001876)1.93724369
100Megaloblastic anemia (HP:0001889)1.93559567
101Glossoptosis (HP:0000162)1.93160209
102Missing ribs (HP:0000921)1.91908518
103Hypokinesia (HP:0002375)1.91787097
104Lipid accumulation in hepatocytes (HP:0006561)1.91271185
105Reduced antithrombin III activity (HP:0001976)1.89980461
106Hepatocellular necrosis (HP:0001404)1.89632045
107Increased hepatocellular lipid droplets (HP:0006565)1.86502237
108Increased CSF lactate (HP:0002490)1.85776298
109Hypoplasia of the capital femoral epiphysis (HP:0003090)1.85233223
110Hyperacusis (HP:0010780)1.84809224
111Duodenal stenosis (HP:0100867)1.84690065
112Small intestinal stenosis (HP:0012848)1.84690065
113Sparse lateral eyebrow (HP:0005338)1.84579966
114Premature rupture of membranes (HP:0001788)1.84383990
115Mitochondrial inheritance (HP:0001427)1.83679841
116Hyperglycinemia (HP:0002154)1.81770082
117Bone marrow hypocellularity (HP:0005528)1.81680173
118Respiratory difficulties (HP:0002880)1.81160034
119Lactic acidosis (HP:0003128)1.80914759
120Cellular immunodeficiency (HP:0005374)1.80796814
121Chromosomal breakage induced by crosslinking agents (HP:0003221)1.79737388
122Squamous cell carcinoma (HP:0002860)1.79599396
123Atrophy/Degeneration involving motor neurons (HP:0007373)1.79478416
124Personality changes (HP:0000751)1.78424454
125Vertebral compression fractures (HP:0002953)1.78024051
126Abnormal umbilical cord blood vessels (HP:0011403)1.77325775
127Single umbilical artery (HP:0001195)1.77325775
128Abnormality of the fetal cardiovascular system (HP:0010948)1.77325775
129Shawl scrotum (HP:0000049)1.76798024
130Increased muscle lipid content (HP:0009058)1.75832876
131Reduced subcutaneous adipose tissue (HP:0003758)1.74743556
132Supernumerary spleens (HP:0009799)1.73215685
133Emotional lability (HP:0000712)1.73066507
134Hypoplastic pelvis (HP:0008839)1.72784666
135Pelvic girdle muscle weakness (HP:0003749)1.72491285
136Abnormal lung lobation (HP:0002101)1.72202349
137Insomnia (HP:0100785)1.71776358
138Aplasia/Hypoplasia involving the musculature (HP:0001460)1.70528030
139Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.69853516
140Abnormality of pyrimidine metabolism (HP:0004353)1.69559810
141Sensory axonal neuropathy (HP:0003390)1.68910390
142Microglossia (HP:0000171)1.67691099
143Increased nuchal translucency (HP:0010880)1.67216928
144Abnormality of the Achilles tendon (HP:0005109)1.65901597
145Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.64338375
146Abnormal protein N-linked glycosylation (HP:0012347)1.64338375
147Abnormal protein glycosylation (HP:0012346)1.64338375
148Abnormal glycosylation (HP:0012345)1.64338375
149Preauricular skin tag (HP:0000384)1.63912180

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TLK15.90279237
2BUB14.60478859
3EIF2AK13.69002827
4WEE13.53391336
5VRK23.36454847
6TESK22.96034262
7SMG12.83575299
8SRPK12.83069477
9NME22.80125233
10CDC72.79656187
11STK162.72471213
12PBK2.64099253
13ARAF2.58420363
14MAP3K132.35595443
15TSSK62.29007903
16IRAK32.20437714
17NEK22.06501933
18TTK1.99321782
19MKNK21.85060311
20MKNK11.83725345
21NEK11.76210093
22PLK11.75259471
23EPHA21.66719109
24ICK1.58634404
25PLK41.56386272
26EIF2AK31.50987338
27CDK71.47345808
28AURKA1.45786951
29DYRK31.39153118
30AURKB1.33563631
31MAP3K111.32118825
32PIM21.32065563
33BRSK21.31734339
34TESK11.31591381
35MAP3K101.29869536
36MAP3K81.23878205
37PLK31.23490031
38VRK11.22336954
39RPS6KB21.19203514
40LATS21.18842141
41ATR1.16693002
42STK38L1.16580969
43ACVR1B1.16344640
44CHEK21.14360405
45PKN21.14253938
46TRIB31.12936486
47MAP3K91.10615634
48BRSK11.08007269
49MOS1.06862169
50ZAK1.05272086
51RPS6KA41.04408962
52CDK41.04177566
53KDR1.00785775
54TAF11.00548761
55CDK191.00492022
56RAF10.97868635
57TRIM280.97586538
58NME10.97485511
59PASK0.96559594
60STK100.91209688
61CHEK10.90455306
62ILK0.90300760
63BRAF0.89090256
64BCKDK0.86392150
65PAK10.84871530
66ERBB40.81614020
67CDK120.79341739
68LIMK10.73331692
69DAPK10.73274825
70MST1R0.73169004
71DAPK30.72033106
72CDK20.71721698
73EEF2K0.71016338
74PAK40.70906833
75PRKCI0.70326262
76ALK0.69794262
77PDK40.68214905
78PDK30.68214905
79CSNK2A20.67421970
80DYRK20.66868526
81CSNK1G30.65807953
82CSNK2A10.62852648
83PRPF4B0.61029980
84LRRK20.61020093
85CCNB10.60007585
86ATM0.59987095
87EPHB20.59922769
88ABL20.59911155
89TGFBR10.58997833
90FLT30.56350963
91STK40.55831116
92SCYL20.54399210
93KSR20.54328156
94CDK80.54324796
95PIM10.54310891
96PNCK0.50411222
97CDK140.50082491
98CSNK1A1L0.49247238
99CDK90.47887965
100MAPKAPK30.46949559
101CDK11A0.46891161
102TAOK20.45135375
103BMX0.44806476
104CDK10.44586795
105LMTK20.43994180
106STK240.42885112
107PTK20.42483304
108RPS6KA50.42025214
109CSNK1E0.41579512
110MAP2K20.41020461
111TAOK10.40994728
112CDK150.40848286
113SIK10.40645130
114CDK180.39748884
115MAPK110.39680691
116PAK20.39529986
117EIF2AK20.37859116
118MTOR0.35400087
119ZAP700.35101459
120AKT30.34811065
121IRAK20.34072383
122CSNK1G10.33865242
123BRD40.33643907
124BLK0.32916645
125AKT20.31569202
126MAP2K30.30921765
127CLK10.30783787
128WNK30.29071681
129STK30.27580366
130PDK20.26952115
131MAP4K10.25499478
132TTN0.23944944

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.53667265
2Ribosome_Homo sapiens_hsa030104.48044982
3Mismatch repair_Homo sapiens_hsa034303.78092184
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.74137577
5RNA polymerase_Homo sapiens_hsa030203.66405295
6Proteasome_Homo sapiens_hsa030503.61313131
7Spliceosome_Homo sapiens_hsa030403.46021365
8RNA transport_Homo sapiens_hsa030133.15440021
9One carbon pool by folate_Homo sapiens_hsa006702.81482938
10Homologous recombination_Homo sapiens_hsa034402.80971491
11Base excision repair_Homo sapiens_hsa034102.78467032
12Nucleotide excision repair_Homo sapiens_hsa034202.66445664
13Pyrimidine metabolism_Homo sapiens_hsa002402.53084066
14Cell cycle_Homo sapiens_hsa041102.38735714
15Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.38420309
16Fanconi anemia pathway_Homo sapiens_hsa034601.96327674
17Basal transcription factors_Homo sapiens_hsa030221.83043687
18mRNA surveillance pathway_Homo sapiens_hsa030151.64138933
19RNA degradation_Homo sapiens_hsa030181.51779891
20Selenocompound metabolism_Homo sapiens_hsa004501.50943601
21p53 signaling pathway_Homo sapiens_hsa041151.41293075
22Sulfur relay system_Homo sapiens_hsa041221.39444972
23Purine metabolism_Homo sapiens_hsa002301.30911029
24Non-homologous end-joining_Homo sapiens_hsa034501.30391301
25Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.17370562
26Epstein-Barr virus infection_Homo sapiens_hsa051691.16025957
27Vitamin B6 metabolism_Homo sapiens_hsa007501.14578556
28Folate biosynthesis_Homo sapiens_hsa007901.13600083
29Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.05921126
30Biosynthesis of amino acids_Homo sapiens_hsa012301.05207402
31Fatty acid elongation_Homo sapiens_hsa000621.02306200
32Huntingtons disease_Homo sapiens_hsa050161.01401926
33Parkinsons disease_Homo sapiens_hsa050120.98424140
34Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.97600791
35Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.95649971
36Cysteine and methionine metabolism_Homo sapiens_hsa002700.94294821
37Cyanoamino acid metabolism_Homo sapiens_hsa004600.94026114
38Pentose phosphate pathway_Homo sapiens_hsa000300.90384813
39Oocyte meiosis_Homo sapiens_hsa041140.84283948
40Steroid biosynthesis_Homo sapiens_hsa001000.82753883
41Oxidative phosphorylation_Homo sapiens_hsa001900.80960938
42Systemic lupus erythematosus_Homo sapiens_hsa053220.79915844
43Protein export_Homo sapiens_hsa030600.79909767
44Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.78700062
45Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.77710879
46Carbon metabolism_Homo sapiens_hsa012000.75974750
47Thyroid cancer_Homo sapiens_hsa052160.75771668
48Viral carcinogenesis_Homo sapiens_hsa052030.75347725
49Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.72243297
502-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.70873588
51HTLV-I infection_Homo sapiens_hsa051660.68994567
52Herpes simplex infection_Homo sapiens_hsa051680.68438151
53Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.67973604
54Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.65931865
55Drug metabolism - other enzymes_Homo sapiens_hsa009830.62422862
56Antigen processing and presentation_Homo sapiens_hsa046120.61855485
57Bladder cancer_Homo sapiens_hsa052190.57923696
58Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.53430335
59Vibrio cholerae infection_Homo sapiens_hsa051100.52318606
60Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.50777520
61Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.50581596
62Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.50536171
63Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.48895403
64Basal cell carcinoma_Homo sapiens_hsa052170.47606100
65Glutathione metabolism_Homo sapiens_hsa004800.47319953
66Fructose and mannose metabolism_Homo sapiens_hsa000510.47088176
67Pancreatic cancer_Homo sapiens_hsa052120.45651594
68Hippo signaling pathway_Homo sapiens_hsa043900.45221337
69MicroRNAs in cancer_Homo sapiens_hsa052060.43405820
70Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.42441384
71Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.42299084
72Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.41057508
73Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.36798638
74Small cell lung cancer_Homo sapiens_hsa052220.36610386
75Non-small cell lung cancer_Homo sapiens_hsa052230.36273687
76Galactose metabolism_Homo sapiens_hsa000520.35578492
77Fatty acid metabolism_Homo sapiens_hsa012120.35116720
78Apoptosis_Homo sapiens_hsa042100.33912277
79HIF-1 signaling pathway_Homo sapiens_hsa040660.33736120
80Central carbon metabolism in cancer_Homo sapiens_hsa052300.33619644
81Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.33033834
82Lysine degradation_Homo sapiens_hsa003100.32666506
83Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.31165739
84Metabolic pathways_Homo sapiens_hsa011000.30163189
85Alzheimers disease_Homo sapiens_hsa050100.29708156
86Cardiac muscle contraction_Homo sapiens_hsa042600.29602447
87TGF-beta signaling pathway_Homo sapiens_hsa043500.29171370
88Acute myeloid leukemia_Homo sapiens_hsa052210.28270097
89Phenylalanine metabolism_Homo sapiens_hsa003600.28025515
90Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.27504512
91Hedgehog signaling pathway_Homo sapiens_hsa043400.27269813
92Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.25345299
93Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.24519641
94Legionellosis_Homo sapiens_hsa051340.23232613
95Sulfur metabolism_Homo sapiens_hsa009200.22877691
96Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.21370142
97Arginine and proline metabolism_Homo sapiens_hsa003300.20662626
98Viral myocarditis_Homo sapiens_hsa054160.20560938
99Hepatitis B_Homo sapiens_hsa051610.20223737
100Primary immunodeficiency_Homo sapiens_hsa053400.19315976
101Prion diseases_Homo sapiens_hsa050200.18699731
102Colorectal cancer_Homo sapiens_hsa052100.18650836
103Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.17373462
104Regulation of autophagy_Homo sapiens_hsa041400.17185973
105Shigellosis_Homo sapiens_hsa051310.16643823
106Chronic myeloid leukemia_Homo sapiens_hsa052200.16270436
107Alcoholism_Homo sapiens_hsa050340.14879968
108N-Glycan biosynthesis_Homo sapiens_hsa005100.14484466
109Notch signaling pathway_Homo sapiens_hsa043300.14381143
110Wnt signaling pathway_Homo sapiens_hsa043100.13227663
111Pathways in cancer_Homo sapiens_hsa052000.12992483
112Prostate cancer_Homo sapiens_hsa052150.09977985
113Renin-angiotensin system_Homo sapiens_hsa046140.09617819
114Arachidonic acid metabolism_Homo sapiens_hsa005900.09508559
115Tight junction_Homo sapiens_hsa045300.08798724
116Measles_Homo sapiens_hsa051620.08664334
117Melanoma_Homo sapiens_hsa052180.07925994
118Pyruvate metabolism_Homo sapiens_hsa006200.07338298

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