

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 6.54559796 |
| 2 | negative regulation of cell killing (GO:0031342) | 6.54172195 |
| 3 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 6.54172195 |
| 4 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.84632625 |
| 5 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 5.83878609 |
| 6 | antigen processing and presentation of endogenous antigen (GO:0019883) | 5.82410329 |
| 7 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 5.74078654 |
| 8 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 5.74078654 |
| 9 | modulation by symbiont of host immune response (GO:0052553) | 5.74078654 |
| 10 | positive regulation by symbiont of host defense response (GO:0052509) | 5.74078654 |
| 11 | modulation by symbiont of host defense response (GO:0052031) | 5.74078654 |
| 12 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 5.74078654 |
| 13 | neutrophil activation involved in immune response (GO:0002283) | 5.67324793 |
| 14 | detection of other organism (GO:0098543) | 5.33519956 |
| 15 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 5.26282857 |
| 16 | detection of bacterium (GO:0016045) | 5.17805022 |
| 17 | response to peptidoglycan (GO:0032494) | 4.90054669 |
| 18 | macrophage activation involved in immune response (GO:0002281) | 4.81711854 |
| 19 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.77307948 |
| 20 | leukocyte aggregation (GO:0070486) | 4.64259807 |
| 21 | detection of external biotic stimulus (GO:0098581) | 4.43781852 |
| 22 | cellular extravasation (GO:0045123) | 4.43010637 |
| 23 | neutrophil activation (GO:0042119) | 4.35671389 |
| 24 | negative regulation of interleukin-12 production (GO:0032695) | 4.30808173 |
| 25 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.21890569 |
| 26 | leukocyte migration involved in inflammatory response (GO:0002523) | 4.21268565 |
| 27 | regulation of gamma-delta T cell activation (GO:0046643) | 4.20732597 |
| 28 | respiratory burst (GO:0045730) | 4.15004444 |
| 29 | detection of molecule of bacterial origin (GO:0032490) | 4.07789435 |
| 30 | response to interleukin-15 (GO:0070672) | 4.06226644 |
| 31 | immunoglobulin mediated immune response (GO:0016064) | 4.00400081 |
| 32 | response to host immune response (GO:0052572) | 3.96809310 |
| 33 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.96809310 |
| 34 | granulocyte activation (GO:0036230) | 3.93872255 |
| 35 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.93569795 |
| 36 | * negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.93191743 |
| 37 | regulation of mast cell degranulation (GO:0043304) | 3.91442489 |
| 38 | detection of biotic stimulus (GO:0009595) | 3.90832870 |
| 39 | microglial cell activation (GO:0001774) | 3.83300762 |
| 40 | myeloid cell activation involved in immune response (GO:0002275) | 3.75642016 |
| 41 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 3.75500711 |
| 42 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.71197286 |
| 43 | cellular response to interleukin-15 (GO:0071350) | 3.70307588 |
| 44 | response to host defenses (GO:0052200) | 3.69968296 |
| 45 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.69968296 |
| 46 | response to host (GO:0075136) | 3.69968296 |
| 47 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 3.67953464 |
| 48 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.61959852 |
| 49 | regulation of mast cell activation involved in immune response (GO:0033006) | 3.60168194 |
| 50 | macrophage activation (GO:0042116) | 3.58425171 |
| 51 | positive regulation of mast cell activation (GO:0033005) | 3.57878373 |
| 52 | * negative regulation of leukocyte mediated immunity (GO:0002704) | 3.57367510 |
| 53 | neutrophil mediated immunity (GO:0002446) | 3.56880157 |
| 54 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.53049844 |
| 55 | regulation of leukocyte degranulation (GO:0043300) | 3.51169010 |
| 56 | regulation of T cell tolerance induction (GO:0002664) | 3.48412295 |
| 57 | response to muramyl dipeptide (GO:0032495) | 3.41711029 |
| 58 | regulation of tolerance induction (GO:0002643) | 3.41705957 |
| 59 | negative regulation of phagocytosis (GO:0050765) | 3.40010080 |
| 60 | B cell receptor signaling pathway (GO:0050853) | 3.35678855 |
| 61 | regulation of mast cell activation (GO:0033003) | 3.35670200 |
| 62 | regulation of B cell differentiation (GO:0045577) | 3.35167035 |
| 63 | cellular response to type I interferon (GO:0071357) | 3.35049038 |
| 64 | type I interferon signaling pathway (GO:0060337) | 3.35049038 |
| 65 | leukocyte degranulation (GO:0043299) | 3.34063758 |
| 66 | response to type I interferon (GO:0034340) | 3.32817689 |
| 67 | positive regulation of B cell differentiation (GO:0045579) | 3.32302648 |
| 68 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.24452126 |
| 69 | germinal center formation (GO:0002467) | 3.19568443 |
| 70 | negative thymic T cell selection (GO:0045060) | 3.19433816 |
| 71 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 3.18127347 |
| 72 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.16911295 |
| 73 | defense response to protozoan (GO:0042832) | 3.16165534 |
| 74 | B cell mediated immunity (GO:0019724) | 3.13256379 |
| 75 | positive thymic T cell selection (GO:0045059) | 3.13073899 |
| 76 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.12650167 |
| 77 | negative T cell selection (GO:0043383) | 3.10797368 |
| 78 | positive regulation of mast cell degranulation (GO:0043306) | 3.10163171 |
| 79 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 3.10163171 |
| 80 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.07976626 |
| 81 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.07326201 |
| 82 | regulation of regulated secretory pathway (GO:1903305) | 3.07059653 |
| 83 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.06217652 |
| 84 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.06217652 |
| 85 | negative regulation of interleukin-6 production (GO:0032715) | 3.05736169 |
| 86 | myeloid leukocyte mediated immunity (GO:0002444) | 3.05141663 |
| 87 | regulation of natural killer cell mediated immunity (GO:0002715) | 3.01979905 |
| 88 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 3.01979905 |
| 89 | negative regulation of innate immune response (GO:0045824) | 3.01601873 |
| 90 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.01576743 |
| 91 | negative regulation of type 2 immune response (GO:0002829) | 3.01373205 |
| 92 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 2.96619977 |
| 93 | tolerance induction (GO:0002507) | 2.94861657 |
| 94 | activated T cell proliferation (GO:0050798) | 2.92298023 |
| 95 | dendritic cell migration (GO:0036336) | 2.89107330 |
| 96 | positive regulation of tolerance induction (GO:0002645) | 2.87958977 |
| 97 | dendritic cell chemotaxis (GO:0002407) | 2.84563701 |
| 98 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 2.84480688 |
| 99 | myeloid leukocyte activation (GO:0002274) | 2.84419428 |
| 100 | T cell selection (GO:0045058) | 2.84046897 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.21217341 |
| 2 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.64138802 |
| 3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.85679261 |
| 4 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.67088983 |
| 5 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.65595770 |
| 6 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.17894682 |
| 7 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.12807080 |
| 8 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.97648946 |
| 9 | * VDR_21846776_ChIP-Seq_THP-1_Human | 2.90396317 |
| 10 | * VDR_24763502_ChIP-Seq_THP-1_Human | 2.75304333 |
| 11 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.73057676 |
| 12 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.68703279 |
| 13 | * SPI1_23547873_ChIP-Seq_NB4_Human | 2.66003065 |
| 14 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.65509760 |
| 15 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.61410427 |
| 16 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.60058549 |
| 17 | * SPI1_23127762_ChIP-Seq_K562_Human | 2.53562005 |
| 18 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.51711661 |
| 19 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.40409076 |
| 20 | * MAF_26560356_Chip-Seq_TH1_Human | 2.40291206 |
| 21 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.39587554 |
| 22 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.33303897 |
| 23 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 2.32241763 |
| 24 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.28083237 |
| 25 | MYB_26560356_Chip-Seq_TH2_Human | 2.23316555 |
| 26 | UTX_26944678_Chip-Seq_JUKART_Human | 2.21134854 |
| 27 | * E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.20563071 |
| 28 | MYC_22102868_ChIP-Seq_BL_Human | 2.17682728 |
| 29 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 2.16403380 |
| 30 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 2.14143941 |
| 31 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.13205722 |
| 32 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.12101569 |
| 33 | * KDM2B_26808549_Chip-Seq_SUP-B15_Human | 2.04771626 |
| 34 | TCF7_22412390_ChIP-Seq_EML_Mouse | 2.04174919 |
| 35 | MYB_26560356_Chip-Seq_TH1_Human | 1.94170129 |
| 36 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.93026381 |
| 37 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.91556101 |
| 38 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.83075457 |
| 39 | MAF_26560356_Chip-Seq_TH2_Human | 1.80926166 |
| 40 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.78754642 |
| 41 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.76161593 |
| 42 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.75690180 |
| 43 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.70070529 |
| 44 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.69630137 |
| 45 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.67387364 |
| 46 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.66995374 |
| 47 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.58982464 |
| 48 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.58630417 |
| 49 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.58313159 |
| 50 | * GATA3_27048872_Chip-Seq_THYMUS_Human | 1.58119024 |
| 51 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.56035269 |
| 52 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.54161981 |
| 53 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.53639739 |
| 54 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.47853623 |
| 55 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.47776161 |
| 56 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.46097555 |
| 57 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.42900091 |
| 58 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.39353465 |
| 59 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.38592183 |
| 60 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.38321361 |
| 61 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.38062187 |
| 62 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.37200761 |
| 63 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.32325074 |
| 64 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.31896037 |
| 65 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.29294236 |
| 66 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.27645529 |
| 67 | GATA1_19941826_ChIP-Seq_K562_Human | 1.26481514 |
| 68 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.23965188 |
| 69 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.23489002 |
| 70 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.22877724 |
| 71 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.22782439 |
| 72 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.19709140 |
| 73 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.19308647 |
| 74 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.18883623 |
| 75 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.17875155 |
| 76 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.17595086 |
| 77 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.17282042 |
| 78 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.16589005 |
| 79 | * GATA3_26560356_Chip-Seq_TH2_Human | 1.16001184 |
| 80 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.15268017 |
| 81 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.15145211 |
| 82 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.14654795 |
| 83 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.12248588 |
| 84 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.10767043 |
| 85 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.09201856 |
| 86 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.07219403 |
| 87 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.06509084 |
| 88 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.05650894 |
| 89 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.03372955 |
| 90 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.03076976 |
| 91 | GATA1_22025678_ChIP-Seq_K562_Human | 0.97546151 |
| 92 | * TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.97285860 |
| 93 | GATA2_19941826_ChIP-Seq_K562_Human | 0.95533253 |
| 94 | * RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.92958744 |
| 95 | * NCOR1_26117541_ChIP-Seq_K562_Human | 0.92719723 |
| 96 | * SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.91972559 |
| 97 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.89209458 |
| 98 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.88218194 |
| 99 | RACK7_27058665_Chip-Seq_MCF-7_Human | 0.87715844 |
| 100 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.86933893 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003724_increased_susceptibility_to | 4.92781549 |
| 2 | MP0003436_decreased_susceptibility_to | 4.45349119 |
| 3 | MP0001835_abnormal_antigen_presentation | 3.74289123 |
| 4 | MP0003303_peritoneal_inflammation | 3.59712501 |
| 5 | MP0002419_abnormal_innate_immunity | 3.20856206 |
| 6 | MP0005025_abnormal_response_to | 2.94981595 |
| 7 | MP0005671_abnormal_response_to | 2.91130263 |
| 8 | MP0000685_abnormal_immune_system | 2.84949383 |
| 9 | MP0001800_abnormal_humoral_immune | 2.83310314 |
| 10 | MP0005000_abnormal_immune_tolerance | 2.81883011 |
| 11 | MP0005387_immune_system_phenotype | 2.81089408 |
| 12 | MP0001790_abnormal_immune_system | 2.81089408 |
| 13 | MP0009785_altered_susceptibility_to | 2.80280723 |
| 14 | MP0006082_CNS_inflammation | 2.72638722 |
| 15 | MP0002723_abnormal_immune_serum | 2.56022084 |
| 16 | MP0002420_abnormal_adaptive_immunity | 2.53952600 |
| 17 | MP0001819_abnormal_immune_cell | 2.51134347 |
| 18 | MP0003300_gastrointestinal_ulcer | 2.49255240 |
| 19 | MP0002452_abnormal_antigen_presenting | 2.46702540 |
| 20 | MP0003191_abnormal_cellular_cholesterol | 2.33686923 |
| 21 | MP0001533_abnormal_skeleton_physiology | 2.29434510 |
| 22 | MP0002148_abnormal_hypersensitivity_rea | 2.28408466 |
| 23 | MP0005464_abnormal_platelet_physiology | 2.28008182 |
| 24 | MP0003763_abnormal_thymus_physiology | 2.25482016 |
| 25 | MP0002405_respiratory_system_inflammati | 2.02786638 |
| 26 | MP0008260_abnormal_autophagy | 2.00727828 |
| 27 | MP0002132_abnormal_respiratory_system | 1.97247625 |
| 28 | MP0003828_pulmonary_edema | 1.96360767 |
| 29 | MP0002398_abnormal_bone_marrow | 1.91503934 |
| 30 | MP0010155_abnormal_intestine_physiology | 1.89414219 |
| 31 | MP0000716_abnormal_immune_system | 1.87555287 |
| 32 | MP0000465_gastrointestinal_hemorrhage | 1.81699541 |
| 33 | MP0009278_abnormal_bone_marrow | 1.81099461 |
| 34 | MP0003172_abnormal_lysosome_physiology | 1.77405728 |
| 35 | MP0001845_abnormal_inflammatory_respons | 1.75305518 |
| 36 | MP0004947_skin_inflammation | 1.70455422 |
| 37 | MP0003866_abnormal_defecation | 1.70214104 |
| 38 | MP0002396_abnormal_hematopoietic_system | 1.66629456 |
| 39 | MP0009333_abnormal_splenocyte_physiolog | 1.63685299 |
| 40 | MP0000689_abnormal_spleen_morphology | 1.58301055 |
| 41 | MP0002722_abnormal_immune_system | 1.57733087 |
| 42 | MP0002429_abnormal_blood_cell | 1.48669304 |
| 43 | MP0003183_abnormal_peptide_metabolism | 1.47963182 |
| 44 | MP0008469_abnormal_protein_level | 1.46988931 |
| 45 | MP0001851_eye_inflammation | 1.43561577 |
| 46 | MP0000703_abnormal_thymus_morphology | 1.41932483 |
| 47 | MP0009764_decreased_sensitivity_to | 1.41529423 |
| 48 | MP0004883_abnormal_blood_vessel | 1.41354748 |
| 49 | MP0000858_altered_metastatic_potential | 1.39100927 |
| 50 | MP0003075_altered_response_to | 1.34130843 |
| 51 | MP0005397_hematopoietic_system_phenotyp | 1.33865257 |
| 52 | MP0001545_abnormal_hematopoietic_system | 1.33865257 |
| 53 | MP0005058_abnormal_lysosome_morphology | 1.32344363 |
| 54 | MP0002277_abnormal_respiratory_mucosa | 1.30293867 |
| 55 | MP0002998_abnormal_bone_remodeling | 1.29711172 |
| 56 | MP0005451_abnormal_body_composition | 1.29286637 |
| 57 | MP0004510_myositis | 1.27974472 |
| 58 | MP0004381_abnormal_hair_follicle | 1.25905408 |
| 59 | MP0005310_abnormal_salivary_gland | 1.21152685 |
| 60 | MP0005164_abnormal_response_to | 1.10839367 |
| 61 | MP0003690_abnormal_glial_cell | 1.10536068 |
| 62 | MP0005166_decreased_susceptibility_to | 1.09132825 |
| 63 | MP0002166_altered_tumor_susceptibility | 1.04778744 |
| 64 | MP0008004_abnormal_stomach_pH | 1.00776474 |
| 65 | MP0005390_skeleton_phenotype | 1.00705092 |
| 66 | MP0001873_stomach_inflammation | 0.97551379 |
| 67 | MP0000343_altered_response_to | 0.94559766 |
| 68 | MP0003448_altered_tumor_morphology | 0.93835353 |
| 69 | MP0003806_abnormal_nucleotide_metabolis | 0.90267012 |
| 70 | MP0001663_abnormal_digestive_system | 0.90074526 |
| 71 | MP0009763_increased_sensitivity_to | 0.88188206 |
| 72 | MP0001853_heart_inflammation | 0.86748719 |
| 73 | MP0002933_joint_inflammation | 0.84534407 |
| 74 | MP0000490_abnormal_crypts_of | 0.84394582 |
| 75 | MP0001986_abnormal_taste_sensitivity | 0.79240029 |
| 76 | MP0003045_fibrosis | 0.78948826 |
| 77 | MP0000604_amyloidosis | 0.77704725 |
| 78 | MP0004808_abnormal_hematopoietic_stem | 0.76234370 |
| 79 | MP0001958_emphysema | 0.73018872 |
| 80 | MP0003795_abnormal_bone_structure | 0.72331060 |
| 81 | MP0005075_abnormal_melanosome_morpholog | 0.71970656 |
| 82 | MP0000249_abnormal_blood_vessel | 0.69445742 |
| 83 | MP0004130_abnormal_muscle_cell | 0.66782762 |
| 84 | MP0009765_abnormal_xenobiotic_induced | 0.65138557 |
| 85 | MP0008874_decreased_physiological_sensi | 0.64823987 |
| 86 | MP0004858_abnormal_nervous_system | 0.61721600 |
| 87 | MP0005083_abnormal_biliary_tract | 0.59886132 |
| 88 | MP0005388_respiratory_system_phenotype | 0.58801105 |
| 89 | MP0002133_abnormal_respiratory_system | 0.58801105 |
| 90 | MP0002138_abnormal_hepatobiliary_system | 0.57437557 |
| 91 | MP0002006_tumorigenesis | 0.57431838 |
| 92 | MP0003656_abnormal_erythrocyte_physiolo | 0.57413285 |
| 93 | MP0005319_abnormal_enzyme/_coenzyme | 0.56350792 |
| 94 | MP0003091_abnormal_cell_migration | 0.56112570 |
| 95 | MP0000015_abnormal_ear_pigmentation | 0.55935335 |
| 96 | MP0009840_abnormal_foam_cell | 0.54300412 |
| 97 | MP0003878_abnormal_ear_physiology | 0.52191490 |
| 98 | MP0005377_hearing/vestibular/ear_phenot | 0.52191490 |
| 99 | MP0005381_digestive/alimentary_phenotyp | 0.50167068 |
| 100 | MP0003566_abnormal_cell_adhesion | 0.47315159 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Eczematoid dermatitis (HP:0000976) | 6.86927983 |
| 2 | Recurrent abscess formation (HP:0002722) | 6.08280335 |
| 3 | Myositis (HP:0100614) | 5.91135584 |
| 4 | Recurrent bacterial skin infections (HP:0005406) | 5.88726153 |
| 5 | Abnormality of macrophages (HP:0004311) | 5.55948520 |
| 6 | Orchitis (HP:0100796) | 5.36936096 |
| 7 | Elevated erythrocyte sedimentation rate (HP:0003565) | 5.05485242 |
| 8 | Stomatitis (HP:0010280) | 5.00343849 |
| 9 | Recurrent gram-negative bacterial infections (HP:0005420) | 4.96296080 |
| 10 | Optic neuritis (HP:0100653) | 4.93162519 |
| 11 | Retrobulbar optic neuritis (HP:0100654) | 4.93162519 |
| 12 | Chronic obstructive pulmonary disease (HP:0006510) | 4.24141454 |
| 13 | Obstructive lung disease (HP:0006536) | 4.24141454 |
| 14 | Gastrointestinal infarctions (HP:0005244) | 4.17889341 |
| 15 | Recurrent fungal infections (HP:0002841) | 4.16991000 |
| 16 | Mediastinal lymphadenopathy (HP:0100721) | 4.07679370 |
| 17 | Meningitis (HP:0001287) | 3.98179165 |
| 18 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.93150674 |
| 19 | Recurrent skin infections (HP:0001581) | 3.91115354 |
| 20 | Spontaneous hematomas (HP:0007420) | 3.78362662 |
| 21 | Increased IgE level (HP:0003212) | 3.77329908 |
| 22 | Hypochromic microcytic anemia (HP:0004840) | 3.74492296 |
| 23 | Prolonged bleeding time (HP:0003010) | 3.69444425 |
| 24 | Encephalitis (HP:0002383) | 3.67104924 |
| 25 | Keratoconjunctivitis sicca (HP:0001097) | 3.61089075 |
| 26 | Gingivitis (HP:0000230) | 3.56338497 |
| 27 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.54606570 |
| 28 | Recurrent cutaneous fungal infections (HP:0011370) | 3.54606570 |
| 29 | Urticaria (HP:0001025) | 3.49245984 |
| 30 | Vasculitis (HP:0002633) | 3.38030909 |
| 31 | Keratoconjunctivitis (HP:0001096) | 3.32823909 |
| 32 | Cellulitis (HP:0100658) | 3.29498307 |
| 33 | Hypochromic anemia (HP:0001931) | 3.24473704 |
| 34 | Chest pain (HP:0100749) | 3.21314121 |
| 35 | Episodic fever (HP:0001954) | 3.20856334 |
| 36 | Petechiae (HP:0000967) | 3.01779439 |
| 37 | Gingival bleeding (HP:0000225) | 3.00573199 |
| 38 | Amyloidosis (HP:0011034) | 3.00339468 |
| 39 | Hemoptysis (HP:0002105) | 2.98944127 |
| 40 | Epistaxis (HP:0000421) | 2.96784519 |
| 41 | Pulmonary infiltrates (HP:0002113) | 2.95257137 |
| 42 | Peritonitis (HP:0002586) | 2.89634947 |
| 43 | Inflammation of the large intestine (HP:0002037) | 2.85460785 |
| 44 | T lymphocytopenia (HP:0005403) | 2.83926661 |
| 45 | Leukocytosis (HP:0001974) | 2.83581365 |
| 46 | Gastrointestinal inflammation (HP:0004386) | 2.78882421 |
| 47 | Pustule (HP:0200039) | 2.77642761 |
| 48 | Abnormality of T cell number (HP:0011839) | 2.72271057 |
| 49 | Recurrent viral infections (HP:0004429) | 2.68531794 |
| 50 | Arterial thrombosis (HP:0004420) | 2.67891916 |
| 51 | Anorexia (HP:0002039) | 2.64787843 |
| 52 | Panhypogammaglobulinemia (HP:0003139) | 2.62653905 |
| 53 | Pulmonary embolism (HP:0002204) | 2.61445220 |
| 54 | Granulocytopenia (HP:0001913) | 2.54012019 |
| 55 | Purpura (HP:0000979) | 2.53623112 |
| 56 | Osteomyelitis (HP:0002754) | 2.53104328 |
| 57 | Increased IgM level (HP:0003496) | 2.52346834 |
| 58 | Abnormality of T cells (HP:0002843) | 2.51791216 |
| 59 | Microcytic anemia (HP:0001935) | 2.47129248 |
| 60 | Hypergammaglobulinemia (HP:0010702) | 2.33118618 |
| 61 | Sepsis (HP:0100806) | 2.31032458 |
| 62 | Colitis (HP:0002583) | 2.27721279 |
| 63 | Lymphopenia (HP:0001888) | 2.26572543 |
| 64 | Abnormality of the pleura (HP:0002103) | 2.26436298 |
| 65 | Abnormal platelet volume (HP:0011876) | 2.25872709 |
| 66 | Hepatosplenomegaly (HP:0001433) | 2.24474835 |
| 67 | Abnormality of T cell physiology (HP:0011840) | 2.20965658 |
| 68 | Abnormality of the peritoneum (HP:0002585) | 2.19576113 |
| 69 | Increased cerebral lipofuscin (HP:0011813) | 2.19131349 |
| 70 | Gangrene (HP:0100758) | 2.16415406 |
| 71 | Increased serum ferritin (HP:0003281) | 2.11427336 |
| 72 | Skin ulcer (HP:0200042) | 2.11190983 |
| 73 | Glomerulopathy (HP:0100820) | 2.10703239 |
| 74 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.10637489 |
| 75 | Loss of speech (HP:0002371) | 2.03579919 |
| 76 | Abnormality of iron homeostasis (HP:0011031) | 2.03227631 |
| 77 | Abnormality of the endocardium (HP:0004306) | 2.03196492 |
| 78 | Vertigo (HP:0002321) | 2.03029020 |
| 79 | Premature loss of primary teeth (HP:0006323) | 2.02654750 |
| 80 | Eosinophilia (HP:0001880) | 2.01740633 |
| 81 | Acne (HP:0001061) | 2.01720297 |
| 82 | Abnormality of glycolipid metabolism (HP:0010969) | 1.99904780 |
| 83 | Abnormality of liposaccharide metabolism (HP:0010968) | 1.99904780 |
| 84 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 1.99904780 |
| 85 | Agammaglobulinemia (HP:0004432) | 1.99701217 |
| 86 | Abnormality of the pericardium (HP:0001697) | 1.99393149 |
| 87 | Polycythemia (HP:0001901) | 1.95794925 |
| 88 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 1.95099447 |
| 89 | Chronic otitis media (HP:0000389) | 1.93742591 |
| 90 | Slow saccadic eye movements (HP:0000514) | 1.91870767 |
| 91 | IgM deficiency (HP:0002850) | 1.90689898 |
| 92 | Skin rash (HP:0000988) | 1.88863209 |
| 93 | Acute hepatic failure (HP:0006554) | 1.87314951 |
| 94 | Systemic lupus erythematosus (HP:0002725) | 1.86756155 |
| 95 | Keratitis (HP:0000491) | 1.86745507 |
| 96 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.86636809 |
| 97 | Polyneuropathy (HP:0001271) | 1.80473948 |
| 98 | Recurrent pneumonia (HP:0006532) | 1.79426279 |
| 99 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 1.76393071 |
| 100 | Dysostosis multiplex (HP:0000943) | 1.76041871 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RIPK4 | 4.76989341 |
| 2 | MAP4K1 | 3.61671936 |
| 3 | MAP2K3 | 3.15685905 |
| 4 | ERN1 | 3.09806347 |
| 5 | BLK | 3.02363259 |
| 6 | IRAK4 | 2.93765092 |
| 7 | TYK2 | 2.85347769 |
| 8 | FES | 2.72790203 |
| 9 | CSK | 2.63436365 |
| 10 | TNK2 | 2.49261199 |
| 11 | GRK6 | 2.44742515 |
| 12 | PRPF4B | 2.40427679 |
| 13 | ZAP70 | 2.22668318 |
| 14 | EPHB1 | 2.19059632 |
| 15 | MAP3K3 | 2.00358992 |
| 16 | BTK | 1.92136588 |
| 17 | TAOK1 | 1.87398340 |
| 18 | HCK | 1.80391254 |
| 19 | MAP3K11 | 1.77626773 |
| 20 | JAK3 | 1.74502598 |
| 21 | TXK | 1.70718602 |
| 22 | SYK | 1.68046919 |
| 23 | FGR | 1.58778028 |
| 24 | TBK1 | 1.43772805 |
| 25 | IKBKE | 1.38291005 |
| 26 | JAK2 | 1.35807834 |
| 27 | LYN | 1.34754489 |
| 28 | MAP3K14 | 1.34313306 |
| 29 | MAP3K1 | 1.32682277 |
| 30 | JAK1 | 1.32576588 |
| 31 | SIK3 | 1.31759939 |
| 32 | MAP3K13 | 1.29440864 |
| 33 | KIT | 1.29309034 |
| 34 | CSF1R | 1.29272049 |
| 35 | KSR2 | 1.24345617 |
| 36 | LCK | 1.21208854 |
| 37 | TAOK3 | 1.18949974 |
| 38 | ITK | 1.10295345 |
| 39 | TRIB3 | 1.07215141 |
| 40 | PRKD2 | 1.06291288 |
| 41 | MARK2 | 1.06197922 |
| 42 | YES1 | 1.04971619 |
| 43 | MARK3 | 1.01247899 |
| 44 | TEC | 1.00091796 |
| 45 | PTK6 | 1.00009283 |
| 46 | TAOK2 | 0.99961553 |
| 47 | TESK2 | 0.98378810 |
| 48 | PDK1 | 0.90829441 |
| 49 | TGFBR2 | 0.90356340 |
| 50 | STK10 | 0.90138591 |
| 51 | CDK19 | 0.88924346 |
| 52 | MAP3K6 | 0.83328140 |
| 53 | IRAK1 | 0.81826734 |
| 54 | PDPK1 | 0.81398654 |
| 55 | IKBKB | 0.80071346 |
| 56 | MAPK12 | 0.78156514 |
| 57 | BMPR2 | 0.77406039 |
| 58 | SIK2 | 0.77218631 |
| 59 | MATK | 0.76515244 |
| 60 | MAP3K7 | 0.76504660 |
| 61 | SMG1 | 0.75920845 |
| 62 | IRAK2 | 0.73904271 |
| 63 | FYN | 0.69976550 |
| 64 | MAPK7 | 0.69609205 |
| 65 | LRRK2 | 0.69588352 |
| 66 | PIK3CG | 0.67620020 |
| 67 | PTK2B | 0.65374820 |
| 68 | CDC42BPA | 0.58964518 |
| 69 | MAP3K2 | 0.58490022 |
| 70 | SIK1 | 0.57320048 |
| 71 | DYRK1B | 0.57312850 |
| 72 | HIPK2 | 0.56955401 |
| 73 | MAP2K4 | 0.56604384 |
| 74 | PRKCQ | 0.55676679 |
| 75 | MAP3K5 | 0.53499205 |
| 76 | EPHA3 | 0.52706086 |
| 77 | STK11 | 0.51938603 |
| 78 | STK38 | 0.49802158 |
| 79 | FGFR4 | 0.48071605 |
| 80 | RPS6KL1 | 0.46633076 |
| 81 | RPS6KC1 | 0.46633076 |
| 82 | RET | 0.46369908 |
| 83 | SGK3 | 0.45671929 |
| 84 | FGFR3 | 0.43489503 |
| 85 | PRKG2 | 0.43054013 |
| 86 | NLK | 0.41151699 |
| 87 | MAPKAPK2 | 0.40337071 |
| 88 | RAF1 | 0.40274785 |
| 89 | MAP2K6 | 0.39642669 |
| 90 | PIM1 | 0.39380397 |
| 91 | GRK7 | 0.39354180 |
| 92 | RPS6KA6 | 0.37951299 |
| 93 | CAMKK1 | 0.35822381 |
| 94 | DAPK2 | 0.35167804 |
| 95 | MAP2K2 | 0.31217575 |
| 96 | MOS | 0.30618618 |
| 97 | PRKCD | 0.29923265 |
| 98 | PRKCH | 0.29315198 |
| 99 | PRKD1 | 0.29280216 |
| 100 | KSR1 | 0.26874504 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Osteoclast differentiation_Homo sapiens_hsa04380 | 3.03983825 |
| 2 | Leishmaniasis_Homo sapiens_hsa05140 | 2.96904962 |
| 3 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.84667686 |
| 4 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.40807765 |
| 5 | Allograft rejection_Homo sapiens_hsa05330 | 2.39067771 |
| 6 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.34481708 |
| 7 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.23791905 |
| 8 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.20742231 |
| 9 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 2.14136322 |
| 10 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.13877658 |
| 11 | Tuberculosis_Homo sapiens_hsa05152 | 2.12102538 |
| 12 | Malaria_Homo sapiens_hsa05144 | 1.92430419 |
| 13 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.90012326 |
| 14 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.79995218 |
| 15 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.75715886 |
| 16 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.75211793 |
| 17 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.73224978 |
| 18 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.72383858 |
| 19 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.69604198 |
| 20 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.69294203 |
| 21 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.68333059 |
| 22 | Measles_Homo sapiens_hsa05162 | 1.67655351 |
| 23 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.66867275 |
| 24 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.63287171 |
| 25 | Viral myocarditis_Homo sapiens_hsa05416 | 1.62668662 |
| 26 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.52531239 |
| 27 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.46379056 |
| 28 | Other glycan degradation_Homo sapiens_hsa00511 | 1.44848329 |
| 29 | Phagosome_Homo sapiens_hsa04145 | 1.43113985 |
| 30 | Legionellosis_Homo sapiens_hsa05134 | 1.40862555 |
| 31 | Influenza A_Homo sapiens_hsa05164 | 1.40476241 |
| 32 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.36369071 |
| 33 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.33276465 |
| 34 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.31725307 |
| 35 | Platelet activation_Homo sapiens_hsa04611 | 1.31463658 |
| 36 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.28541889 |
| 37 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.28329739 |
| 38 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.28273740 |
| 39 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.26339103 |
| 40 | Asthma_Homo sapiens_hsa05310 | 1.23766157 |
| 41 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.20372569 |
| 42 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.16369874 |
| 43 | Pertussis_Homo sapiens_hsa05133 | 1.11402733 |
| 44 | Hepatitis B_Homo sapiens_hsa05161 | 1.06420741 |
| 45 | Shigellosis_Homo sapiens_hsa05131 | 1.03956534 |
| 46 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.01958167 |
| 47 | Salmonella infection_Homo sapiens_hsa05132 | 1.00746801 |
| 48 | Hepatitis C_Homo sapiens_hsa05160 | 1.00034906 |
| 49 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.98789753 |
| 50 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.94875749 |
| 51 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.94122646 |
| 52 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.93905407 |
| 53 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.91117430 |
| 54 | Endocytosis_Homo sapiens_hsa04144 | 0.87778067 |
| 55 | Apoptosis_Homo sapiens_hsa04210 | 0.86562583 |
| 56 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.83573001 |
| 57 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.83115664 |
| 58 | Lysosome_Homo sapiens_hsa04142 | 0.81561461 |
| 59 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.78265853 |
| 60 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.76890371 |
| 61 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.76489638 |
| 62 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.75725521 |
| 63 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.75433491 |
| 64 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.74219722 |
| 65 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.73163270 |
| 66 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.71812328 |
| 67 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.71421749 |
| 68 | Amoebiasis_Homo sapiens_hsa05146 | 0.70053672 |
| 69 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.65931953 |
| 70 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.65832869 |
| 71 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.65695396 |
| 72 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.64299838 |
| 73 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.63419504 |
| 74 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.63188651 |
| 75 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.63032006 |
| 76 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.62261422 |
| 77 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.61194466 |
| 78 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.61107989 |
| 79 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.57782259 |
| 80 | Endometrial cancer_Homo sapiens_hsa05213 | 0.57728531 |
| 81 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.57641025 |
| 82 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.55554673 |
| 83 | HTLV-I infection_Homo sapiens_hsa05166 | 0.54410789 |
| 84 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.54329874 |
| 85 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.53887732 |
| 86 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.50827299 |
| 87 | Colorectal cancer_Homo sapiens_hsa05210 | 0.50598590 |
| 88 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.49243012 |
| 89 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.48600251 |
| 90 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.48482342 |
| 91 | Insulin resistance_Homo sapiens_hsa04931 | 0.48138218 |
| 92 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.47580885 |
| 93 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.46770663 |
| 94 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.43954249 |
| 95 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.43213913 |
| 96 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.39576278 |
| 97 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.39262715 |
| 98 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.37175596 |
| 99 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.35460920 |
| 100 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.33925310 |

