

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.56784077 |
| 2 | proteasome assembly (GO:0043248) | 4.96175299 |
| 3 | ATP synthesis coupled proton transport (GO:0015986) | 4.54521989 |
| 4 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.54521989 |
| 5 | CENP-A containing nucleosome assembly (GO:0034080) | 4.53095449 |
| 6 | chromatin remodeling at centromere (GO:0031055) | 4.49361620 |
| 7 | establishment of integrated proviral latency (GO:0075713) | 4.45804421 |
| 8 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.40240129 |
| 9 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.29003464 |
| 10 | protein neddylation (GO:0045116) | 4.19041058 |
| 11 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.15844637 |
| 12 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 4.11163040 |
| 13 | cullin deneddylation (GO:0010388) | 3.99289729 |
| 14 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.99032514 |
| 15 | chaperone-mediated protein transport (GO:0072321) | 3.97689236 |
| 16 | histone exchange (GO:0043486) | 3.94934142 |
| 17 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.86544623 |
| 18 | negative regulation of ligase activity (GO:0051352) | 3.86544623 |
| 19 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.85871466 |
| 20 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.84540576 |
| 21 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.82527435 |
| 22 | DNA double-strand break processing (GO:0000729) | 3.78675939 |
| 23 | respiratory electron transport chain (GO:0022904) | 3.78280107 |
| 24 | electron transport chain (GO:0022900) | 3.70311009 |
| 25 | protein deneddylation (GO:0000338) | 3.66229158 |
| 26 | protein complex biogenesis (GO:0070271) | 3.64293622 |
| 27 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.62938129 |
| 28 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.62938129 |
| 29 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.62456887 |
| 30 | termination of RNA polymerase III transcription (GO:0006386) | 3.62456887 |
| 31 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.60441509 |
| 32 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.58820018 |
| 33 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.58671507 |
| 34 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.56733803 |
| 35 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.56733803 |
| 36 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.56733803 |
| 37 | ribosome assembly (GO:0042255) | 3.56468661 |
| 38 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.53034762 |
| 39 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.53034762 |
| 40 | respiratory chain complex IV assembly (GO:0008535) | 3.51709034 |
| 41 | rRNA modification (GO:0000154) | 3.46554998 |
| 42 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.46360853 |
| 43 | DNA replication-independent nucleosome organization (GO:0034724) | 3.46360853 |
| 44 | DNA damage response, detection of DNA damage (GO:0042769) | 3.42055601 |
| 45 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.41129502 |
| 46 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.41129502 |
| 47 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.41103351 |
| 48 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.38467629 |
| 49 | establishment of viral latency (GO:0019043) | 3.38402752 |
| 50 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.38162173 |
| 51 | spliceosomal snRNP assembly (GO:0000387) | 3.36753706 |
| 52 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.36644085 |
| 53 | NADH dehydrogenase complex assembly (GO:0010257) | 3.36644085 |
| 54 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.36644085 |
| 55 | DNA replication checkpoint (GO:0000076) | 3.33246142 |
| 56 | regulation of mitochondrial translation (GO:0070129) | 3.31894889 |
| 57 | DNA ligation (GO:0006266) | 3.31030736 |
| 58 | positive regulation of ligase activity (GO:0051351) | 3.24194798 |
| 59 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.23707145 |
| 60 | purine nucleobase biosynthetic process (GO:0009113) | 3.20229983 |
| 61 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.16679382 |
| 62 | ribosomal large subunit biogenesis (GO:0042273) | 3.11634014 |
| 63 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 3.11193594 |
| 64 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.09958128 |
| 65 | cytochrome complex assembly (GO:0017004) | 3.09487191 |
| 66 | histone mRNA metabolic process (GO:0008334) | 3.09042125 |
| 67 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.08098996 |
| 68 | ribosomal small subunit assembly (GO:0000028) | 3.08091510 |
| 69 | maturation of 5.8S rRNA (GO:0000460) | 3.06457437 |
| 70 | mitotic metaphase plate congression (GO:0007080) | 3.05802198 |
| 71 | inner mitochondrial membrane organization (GO:0007007) | 3.05245863 |
| 72 | double-strand break repair via nonhomologous end joining (GO:0006303) | 2.98665829 |
| 73 | non-recombinational repair (GO:0000726) | 2.98665829 |
| 74 | regulation of ligase activity (GO:0051340) | 2.98211075 |
| 75 | rRNA methylation (GO:0031167) | 2.96939184 |
| 76 | metaphase plate congression (GO:0051310) | 2.93760108 |
| 77 | DNA strand elongation (GO:0022616) | 2.91708242 |
| 78 | spindle checkpoint (GO:0031577) | 2.89912174 |
| 79 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.88425797 |
| 80 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.88425797 |
| 81 | isotype switching (GO:0045190) | 2.88425797 |
| 82 | organelle disassembly (GO:1903008) | 2.87926462 |
| 83 | 7-methylguanosine mRNA capping (GO:0006370) | 2.87699636 |
| 84 | protein targeting to mitochondrion (GO:0006626) | 2.86636897 |
| 85 | protein localization to kinetochore (GO:0034501) | 2.86100902 |
| 86 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.85927031 |
| 87 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.85927031 |
| 88 | IMP biosynthetic process (GO:0006188) | 2.85713325 |
| 89 | mitotic spindle checkpoint (GO:0071174) | 2.85686905 |
| 90 | protein-cofactor linkage (GO:0018065) | 2.84632945 |
| 91 | nucleobase biosynthetic process (GO:0046112) | 2.84491172 |
| 92 | kinetochore organization (GO:0051383) | 2.83915448 |
| 93 | translation (GO:0006412) | 2.83895727 |
| 94 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 2.82472244 |
| 95 | negative regulation of sister chromatid segregation (GO:0033046) | 2.82472244 |
| 96 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 2.82472244 |
| 97 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 2.82472244 |
| 98 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 2.82472244 |
| 99 | replication fork processing (GO:0031297) | 2.80413974 |
| 100 | 7-methylguanosine RNA capping (GO:0009452) | 2.79688374 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.81142583 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.21529895 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 4.00191434 |
| 4 | E2F7_22180533_ChIP-Seq_HELA_Human | 3.50525363 |
| 5 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.30894935 |
| 6 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.19046235 |
| 7 | ELK1_19687146_ChIP-ChIP_HELA_Human | 3.05001928 |
| 8 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.97812113 |
| 9 | * HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.83140565 |
| 10 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.78635077 |
| 11 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.72661703 |
| 12 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.69701207 |
| 13 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.64638309 |
| 14 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.56869924 |
| 15 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.47794759 |
| 16 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.39053260 |
| 17 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.15602193 |
| 18 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.10954514 |
| 19 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.09654303 |
| 20 | EWS_26573619_Chip-Seq_HEK293_Human | 2.08519047 |
| 21 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 2.04582964 |
| 22 | FUS_26573619_Chip-Seq_HEK293_Human | 2.04191248 |
| 23 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.99388759 |
| 24 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.97134420 |
| 25 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.94070156 |
| 26 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.88558049 |
| 27 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.86978070 |
| 28 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.82216460 |
| 29 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.81142250 |
| 30 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.81096266 |
| 31 | * ZNF274_21170338_ChIP-Seq_K562_Hela | 1.80413769 |
| 32 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.79423663 |
| 33 | VDR_22108803_ChIP-Seq_LS180_Human | 1.74085914 |
| 34 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.73704573 |
| 35 | * DCP1A_22483619_ChIP-Seq_HELA_Human | 1.72966909 |
| 36 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.72415122 |
| 37 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.68728307 |
| 38 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.66717568 |
| 39 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.62483018 |
| 40 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.61077501 |
| 41 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.60126251 |
| 42 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.59982838 |
| 43 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.57143307 |
| 44 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.55833544 |
| 45 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.55411625 |
| 46 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.53559986 |
| 47 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.53448917 |
| 48 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.49891176 |
| 49 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.49682783 |
| 50 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.45646342 |
| 51 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.45061175 |
| 52 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.44415881 |
| 53 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.41067817 |
| 54 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.39932228 |
| 55 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.39414367 |
| 56 | P300_19829295_ChIP-Seq_ESCs_Human | 1.35231587 |
| 57 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.34251842 |
| 58 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.30157681 |
| 59 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.29392660 |
| 60 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.29077428 |
| 61 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.28970230 |
| 62 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.27019244 |
| 63 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.26928196 |
| 64 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.25160581 |
| 65 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.23535503 |
| 66 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.18132589 |
| 67 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.16227898 |
| 68 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.14656202 |
| 69 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.13092002 |
| 70 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.12655347 |
| 71 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.06875652 |
| 72 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.06074761 |
| 73 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.04587005 |
| 74 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.04323077 |
| 75 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.03083864 |
| 76 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.02477622 |
| 77 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.01978951 |
| 78 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.01925298 |
| 79 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.01271715 |
| 80 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.00834116 |
| 81 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.99757529 |
| 82 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.98756226 |
| 83 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.96587179 |
| 84 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.95817652 |
| 85 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.91107433 |
| 86 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.89685563 |
| 87 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.89533769 |
| 88 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.88853536 |
| 89 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 0.88388223 |
| 90 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.87196188 |
| 91 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.85990571 |
| 92 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.84940072 |
| 93 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.84401975 |
| 94 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.84401975 |
| 95 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.83710204 |
| 96 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.82946337 |
| 97 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.82784085 |
| 98 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.80490492 |
| 99 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.79844760 |
| 100 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.78858509 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008058_abnormal_DNA_repair | 3.73267677 |
| 2 | MP0010094_abnormal_chromosome_stability | 3.49835732 |
| 3 | MP0004957_abnormal_blastocyst_morpholog | 3.16013290 |
| 4 | MP0003693_abnormal_embryo_hatching | 2.99410445 |
| 5 | MP0008877_abnormal_DNA_methylation | 2.87080508 |
| 6 | MP0003111_abnormal_nucleus_morphology | 2.51962862 |
| 7 | MP0003718_maternal_effect | 2.48430448 |
| 8 | MP0002938_white_spotting | 2.46743554 |
| 9 | MP0003077_abnormal_cell_cycle | 2.45337206 |
| 10 | MP0008057_abnormal_DNA_replication | 2.45261981 |
| 11 | MP0003136_yellow_coat_color | 2.40947169 |
| 12 | MP0002102_abnormal_ear_morphology | 2.36979685 |
| 13 | MP0006072_abnormal_retinal_apoptosis | 2.32513785 |
| 14 | MP0000372_irregular_coat_pigmentation | 2.32392568 |
| 15 | MP0006292_abnormal_olfactory_placode | 2.23128303 |
| 16 | MP0003890_abnormal_embryonic-extraembry | 2.20844000 |
| 17 | MP0008932_abnormal_embryonic_tissue | 2.17622994 |
| 18 | MP0003186_abnormal_redox_activity | 2.08214019 |
| 19 | MP0003806_abnormal_nucleotide_metabolis | 2.06426610 |
| 20 | MP0009697_abnormal_copulation | 2.05128211 |
| 21 | MP0008007_abnormal_cellular_replicative | 2.04152438 |
| 22 | MP0001293_anophthalmia | 1.98548289 |
| 23 | MP0003786_premature_aging | 1.90284999 |
| 24 | MP0003941_abnormal_skin_development | 1.82751027 |
| 25 | MP0003011_delayed_dark_adaptation | 1.76242257 |
| 26 | MP0003880_abnormal_central_pattern | 1.74239827 |
| 27 | MP0001529_abnormal_vocalization | 1.72129334 |
| 28 | MP0005253_abnormal_eye_physiology | 1.59392120 |
| 29 | MP0006036_abnormal_mitochondrial_physio | 1.58253584 |
| 30 | MP0001984_abnormal_olfaction | 1.56050659 |
| 31 | MP0005084_abnormal_gallbladder_morpholo | 1.55724899 |
| 32 | MP0010030_abnormal_orbit_morphology | 1.55135026 |
| 33 | MP0006035_abnormal_mitochondrial_morpho | 1.45643428 |
| 34 | MP0003567_abnormal_fetal_cardiomyocyte | 1.44274642 |
| 35 | MP0003121_genomic_imprinting | 1.40561864 |
| 36 | MP0002736_abnormal_nociception_after | 1.38834568 |
| 37 | MP0003937_abnormal_limbs/digits/tail_de | 1.37922103 |
| 38 | MP0005171_absent_coat_pigmentation | 1.34821016 |
| 39 | MP0002638_abnormal_pupillary_reflex | 1.32050505 |
| 40 | MP0004133_heterotaxia | 1.28964437 |
| 41 | MP0005075_abnormal_melanosome_morpholog | 1.24582425 |
| 42 | MP0008789_abnormal_olfactory_epithelium | 1.22131268 |
| 43 | MP0005408_hypopigmentation | 1.21045034 |
| 44 | MP0002210_abnormal_sex_determination | 1.20996574 |
| 45 | MP0002751_abnormal_autonomic_nervous | 1.20711348 |
| 46 | MP0008995_early_reproductive_senescence | 1.20517923 |
| 47 | MP0001286_abnormal_eye_development | 1.15943949 |
| 48 | MP0002233_abnormal_nose_morphology | 1.14858098 |
| 49 | MP0000647_abnormal_sebaceous_gland | 1.14710139 |
| 50 | MP0004147_increased_porphyrin_level | 1.11054558 |
| 51 | MP0002837_dystrophic_cardiac_calcinosis | 1.09938685 |
| 52 | MP0004215_abnormal_myocardial_fiber | 1.09862084 |
| 53 | MP0001929_abnormal_gametogenesis | 1.09576647 |
| 54 | MP0000350_abnormal_cell_proliferation | 1.07941567 |
| 55 | MP0001697_abnormal_embryo_size | 1.06009683 |
| 56 | MP0005645_abnormal_hypothalamus_physiol | 1.05365715 |
| 57 | MP0000631_abnormal_neuroendocrine_gland | 1.05226870 |
| 58 | MP0003195_calcinosis | 1.03891488 |
| 59 | MP0005551_abnormal_eye_electrophysiolog | 1.03708374 |
| 60 | MP0002095_abnormal_skin_pigmentation | 1.03342715 |
| 61 | MP0000653_abnormal_sex_gland | 1.03115790 |
| 62 | MP0002084_abnormal_developmental_patter | 1.02001333 |
| 63 | MP0002234_abnormal_pharynx_morphology | 1.01189269 |
| 64 | MP0006276_abnormal_autonomic_nervous | 1.01000085 |
| 65 | MP0003787_abnormal_imprinting | 1.00821686 |
| 66 | MP0001145_abnormal_male_reproductive | 0.99452758 |
| 67 | MP0001188_hyperpigmentation | 0.96922240 |
| 68 | MP0003119_abnormal_digestive_system | 0.96835946 |
| 69 | MP0001485_abnormal_pinna_reflex | 0.95920971 |
| 70 | MP0002160_abnormal_reproductive_system | 0.94347218 |
| 71 | MP0000358_abnormal_cell_content/ | 0.93954305 |
| 72 | MP0005391_vision/eye_phenotype | 0.92364240 |
| 73 | MP0001730_embryonic_growth_arrest | 0.91919105 |
| 74 | MP0002085_abnormal_embryonic_tissue | 0.91210852 |
| 75 | MP0009379_abnormal_foot_pigmentation | 0.90143278 |
| 76 | MP0002282_abnormal_trachea_morphology | 0.87788970 |
| 77 | MP0002090_abnormal_vision | 0.87444408 |
| 78 | MP0001324_abnormal_eye_pigmentation | 0.85756229 |
| 79 | MP0008872_abnormal_physiological_respon | 0.83073574 |
| 80 | MP0003122_maternal_imprinting | 0.82583864 |
| 81 | MP0002697_abnormal_eye_size | 0.82508578 |
| 82 | MP0005389_reproductive_system_phenotype | 0.81946788 |
| 83 | MP0001672_abnormal_embryogenesis/_devel | 0.81147517 |
| 84 | MP0005380_embryogenesis_phenotype | 0.81147517 |
| 85 | MP0001119_abnormal_female_reproductive | 0.80068034 |
| 86 | MP0004142_abnormal_muscle_tone | 0.79437776 |
| 87 | MP0006054_spinal_hemorrhage | 0.78565122 |
| 88 | MP0002277_abnormal_respiratory_mucosa | 0.75065366 |
| 89 | MP0003283_abnormal_digestive_organ | 0.74294503 |
| 90 | MP0005395_other_phenotype | 0.73714671 |
| 91 | MP0005499_abnormal_olfactory_system | 0.73369958 |
| 92 | MP0005394_taste/olfaction_phenotype | 0.73369958 |
| 93 | MP0003698_abnormal_male_reproductive | 0.72449230 |
| 94 | MP0001177_atelectasis | 0.71441496 |
| 95 | MP0005379_endocrine/exocrine_gland_phen | 0.68927458 |
| 96 | MP0005174_abnormal_tail_pigmentation | 0.67548363 |
| 97 | MP0002088_abnormal_embryonic_growth/wei | 0.65649143 |
| 98 | MP0002163_abnormal_gland_morphology | 0.65226812 |
| 99 | MP0001905_abnormal_dopamine_level | 0.65205813 |
| 100 | MP0002080_prenatal_lethality | 0.65031943 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.48915679 |
| 2 | Increased hepatocellular lipid droplets (HP:0006565) | 4.06048564 |
| 3 | Acute encephalopathy (HP:0006846) | 3.99514708 |
| 4 | Progressive macrocephaly (HP:0004481) | 3.94042173 |
| 5 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.91707842 |
| 6 | Mitochondrial inheritance (HP:0001427) | 3.90070226 |
| 7 | Increased CSF lactate (HP:0002490) | 3.71807490 |
| 8 | Lipid accumulation in hepatocytes (HP:0006561) | 3.59434384 |
| 9 | Abnormality of the labia minora (HP:0012880) | 3.41484061 |
| 10 | Hepatocellular necrosis (HP:0001404) | 3.19225479 |
| 11 | Methylmalonic acidemia (HP:0002912) | 3.13683665 |
| 12 | Colon cancer (HP:0003003) | 3.10595874 |
| 13 | Renal Fanconi syndrome (HP:0001994) | 3.10046064 |
| 14 | Cerebral edema (HP:0002181) | 3.01743472 |
| 15 | Hepatic necrosis (HP:0002605) | 2.93867307 |
| 16 | 3-Methylglutaconic aciduria (HP:0003535) | 2.81012265 |
| 17 | Abnormality of methionine metabolism (HP:0010901) | 2.62481582 |
| 18 | Pancreatic cysts (HP:0001737) | 2.62119851 |
| 19 | Exertional dyspnea (HP:0002875) | 2.56520378 |
| 20 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.53292100 |
| 21 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.53292100 |
| 22 | Congenital, generalized hypertrichosis (HP:0004540) | 2.53252784 |
| 23 | Meckel diverticulum (HP:0002245) | 2.52489423 |
| 24 | Increased serum lactate (HP:0002151) | 2.50222573 |
| 25 | Pancreatic fibrosis (HP:0100732) | 2.44345943 |
| 26 | Abnormal lung lobation (HP:0002101) | 2.43439605 |
| 27 | Abnormality of midbrain morphology (HP:0002418) | 2.43419569 |
| 28 | Molar tooth sign on MRI (HP:0002419) | 2.43419569 |
| 29 | Methylmalonic aciduria (HP:0012120) | 2.42595277 |
| 30 | Aplastic anemia (HP:0001915) | 2.42336636 |
| 31 | Abnormality of the ileum (HP:0001549) | 2.42277903 |
| 32 | Type I transferrin isoform profile (HP:0003642) | 2.39275515 |
| 33 | Abnormality of the anterior horn cell (HP:0006802) | 2.36912551 |
| 34 | Degeneration of anterior horn cells (HP:0002398) | 2.36912551 |
| 35 | Increased intramyocellular lipid droplets (HP:0012240) | 2.34575983 |
| 36 | Lactic acidosis (HP:0003128) | 2.34238592 |
| 37 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.34112507 |
| 38 | True hermaphroditism (HP:0010459) | 2.33575230 |
| 39 | Abnormality of chromosome stability (HP:0003220) | 2.30766343 |
| 40 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.29760769 |
| 41 | Volvulus (HP:0002580) | 2.28870443 |
| 42 | Leukodystrophy (HP:0002415) | 2.27245127 |
| 43 | Respiratory failure (HP:0002878) | 2.25422307 |
| 44 | Medial flaring of the eyebrow (HP:0010747) | 2.24923388 |
| 45 | Increased serum pyruvate (HP:0003542) | 2.23915018 |
| 46 | Abnormality of serum amino acid levels (HP:0003112) | 2.21668032 |
| 47 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.20609608 |
| 48 | Abnormality of alanine metabolism (HP:0010916) | 2.20609608 |
| 49 | Hyperalaninemia (HP:0003348) | 2.20609608 |
| 50 | Macrocytic anemia (HP:0001972) | 2.17292952 |
| 51 | Reticulocytopenia (HP:0001896) | 2.16409304 |
| 52 | Optic disc pallor (HP:0000543) | 2.15506743 |
| 53 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.14461516 |
| 54 | Chromsome breakage (HP:0040012) | 2.11647463 |
| 55 | Septo-optic dysplasia (HP:0100842) | 2.08973836 |
| 56 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.08402371 |
| 57 | Exercise intolerance (HP:0003546) | 2.05564760 |
| 58 | Hyperglycinemia (HP:0002154) | 2.03724842 |
| 59 | Abnormal number of erythroid precursors (HP:0012131) | 2.03594336 |
| 60 | Nephronophthisis (HP:0000090) | 2.00363812 |
| 61 | Abnormality of the preputium (HP:0100587) | 1.99400202 |
| 62 | Duodenal stenosis (HP:0100867) | 1.98598762 |
| 63 | Small intestinal stenosis (HP:0012848) | 1.98598762 |
| 64 | Abnormality of renal resorption (HP:0011038) | 1.97530163 |
| 65 | Intestinal atresia (HP:0011100) | 1.95848747 |
| 66 | Abnormality of glycolysis (HP:0004366) | 1.95847108 |
| 67 | Lethargy (HP:0001254) | 1.95073723 |
| 68 | Abnormal protein glycosylation (HP:0012346) | 1.93382157 |
| 69 | Abnormal glycosylation (HP:0012345) | 1.93382157 |
| 70 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.93382157 |
| 71 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.93382157 |
| 72 | Respiratory difficulties (HP:0002880) | 1.91851293 |
| 73 | Stenosis of the external auditory canal (HP:0000402) | 1.91021829 |
| 74 | Abnormality of the duodenum (HP:0002246) | 1.89608255 |
| 75 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.89358513 |
| 76 | Abnormality of vitamin B metabolism (HP:0004340) | 1.88095197 |
| 77 | Short tibia (HP:0005736) | 1.87154408 |
| 78 | Neoplasm of the adrenal gland (HP:0100631) | 1.86455154 |
| 79 | Congenital primary aphakia (HP:0007707) | 1.84824710 |
| 80 | Supernumerary spleens (HP:0009799) | 1.84478369 |
| 81 | Birth length less than 3rd percentile (HP:0003561) | 1.82704874 |
| 82 | Oral leukoplakia (HP:0002745) | 1.81905616 |
| 83 | Neoplasm of the colon (HP:0100273) | 1.81691222 |
| 84 | Triphalangeal thumb (HP:0001199) | 1.81297054 |
| 85 | Pancytopenia (HP:0001876) | 1.80762702 |
| 86 | Bifid tongue (HP:0010297) | 1.80313227 |
| 87 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.79845233 |
| 88 | Abnormality of the septum pellucidum (HP:0007375) | 1.79766386 |
| 89 | Microvesicular hepatic steatosis (HP:0001414) | 1.79084911 |
| 90 | Genital tract atresia (HP:0001827) | 1.78606850 |
| 91 | Hypothermia (HP:0002045) | 1.77539632 |
| 92 | Abnormality of the pons (HP:0007361) | 1.76427813 |
| 93 | Megaloblastic anemia (HP:0001889) | 1.75832984 |
| 94 | Renal cortical cysts (HP:0000803) | 1.75726529 |
| 95 | Absent septum pellucidum (HP:0001331) | 1.74800255 |
| 96 | Vaginal atresia (HP:0000148) | 1.74369915 |
| 97 | Gait imbalance (HP:0002141) | 1.72880117 |
| 98 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.72443527 |
| 99 | Median cleft lip (HP:0000161) | 1.71446701 |
| 100 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.70783327 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BUB1 | 3.51812112 |
| 2 | MST4 | 3.48822207 |
| 3 | VRK2 | 3.15498195 |
| 4 | SRPK1 | 2.74901230 |
| 5 | CDC7 | 2.68659714 |
| 6 | EIF2AK3 | 2.56506432 |
| 7 | TSSK6 | 2.31071423 |
| 8 | TRIM28 | 2.30433969 |
| 9 | PLK3 | 2.27531471 |
| 10 | NUAK1 | 2.26709790 |
| 11 | MKNK1 | 2.25822363 |
| 12 | MKNK2 | 2.22087529 |
| 13 | ZAK | 2.20832865 |
| 14 | EIF2AK1 | 2.19853652 |
| 15 | PBK | 2.12852190 |
| 16 | VRK1 | 2.05547540 |
| 17 | TNIK | 2.03764896 |
| 18 | WNK3 | 2.02824083 |
| 19 | TTK | 1.98740735 |
| 20 | STK16 | 1.96257825 |
| 21 | NEK1 | 1.95494428 |
| 22 | WEE1 | 1.92738434 |
| 23 | BMPR1B | 1.81489886 |
| 24 | BRSK2 | 1.78317235 |
| 25 | PLK4 | 1.75187713 |
| 26 | MAP4K2 | 1.74734719 |
| 27 | MAP3K12 | 1.66198925 |
| 28 | TAF1 | 1.53912161 |
| 29 | NME1 | 1.43651266 |
| 30 | BCR | 1.42569508 |
| 31 | ACVR1B | 1.33927333 |
| 32 | PASK | 1.33667488 |
| 33 | PLK2 | 1.32331236 |
| 34 | ERBB3 | 1.32222394 |
| 35 | PLK1 | 1.26298611 |
| 36 | FRK | 1.25484516 |
| 37 | STK38L | 1.22451461 |
| 38 | PNCK | 1.04035238 |
| 39 | GRK1 | 1.00485930 |
| 40 | EIF2AK2 | 0.99169387 |
| 41 | DYRK2 | 0.97292817 |
| 42 | CSNK1G1 | 0.89202031 |
| 43 | OXSR1 | 0.88312000 |
| 44 | ATR | 0.87419383 |
| 45 | ADRBK2 | 0.86882229 |
| 46 | MAP3K4 | 0.86789933 |
| 47 | STK3 | 0.84989924 |
| 48 | PDK2 | 0.84703154 |
| 49 | INSRR | 0.79610966 |
| 50 | AURKB | 0.79131309 |
| 51 | CSNK1G2 | 0.78512499 |
| 52 | CSNK1G3 | 0.76632750 |
| 53 | BRSK1 | 0.76604146 |
| 54 | CHEK2 | 0.76143670 |
| 55 | TGFBR1 | 0.69222436 |
| 56 | TAOK3 | 0.68117156 |
| 57 | BCKDK | 0.67382410 |
| 58 | PINK1 | 0.65848032 |
| 59 | ATM | 0.65454013 |
| 60 | DYRK3 | 0.64618294 |
| 61 | TLK1 | 0.64392850 |
| 62 | TXK | 0.62758409 |
| 63 | CDK19 | 0.60158874 |
| 64 | FGFR2 | 0.59073979 |
| 65 | FGFR1 | 0.58726618 |
| 66 | RPS6KA4 | 0.58366531 |
| 67 | STK4 | 0.57974327 |
| 68 | STK39 | 0.57260937 |
| 69 | CASK | 0.56596323 |
| 70 | STK24 | 0.55860045 |
| 71 | CSNK2A1 | 0.55848421 |
| 72 | CSNK2A2 | 0.55798060 |
| 73 | CCNB1 | 0.54157151 |
| 74 | NEK2 | 0.53391811 |
| 75 | CDK3 | 0.49902220 |
| 76 | CSNK1A1L | 0.49875574 |
| 77 | ALK | 0.48548263 |
| 78 | MAP2K7 | 0.48469862 |
| 79 | PAK3 | 0.46805654 |
| 80 | ERBB4 | 0.45576198 |
| 81 | PRKCG | 0.44114045 |
| 82 | PRKCE | 0.42797947 |
| 83 | CHEK1 | 0.42602524 |
| 84 | DAPK1 | 0.41159484 |
| 85 | RPS6KA5 | 0.40641042 |
| 86 | CSNK1E | 0.40342158 |
| 87 | MINK1 | 0.39945479 |
| 88 | NLK | 0.38587486 |
| 89 | CLK1 | 0.37015767 |
| 90 | CDK8 | 0.35043737 |
| 91 | MYLK | 0.33712048 |
| 92 | TEC | 0.32542194 |
| 93 | LATS1 | 0.30262332 |
| 94 | MAPK13 | 0.28276902 |
| 95 | CSNK1A1 | 0.25790119 |
| 96 | KDR | 0.25534046 |
| 97 | PRKDC | 0.25485416 |
| 98 | CDK1 | 0.25327164 |
| 99 | WNK4 | 0.24902397 |
| 100 | LIMK1 | 0.23992682 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.66912789 |
| 2 | Protein export_Homo sapiens_hsa03060 | 3.82998050 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.46908613 |
| 4 | Mismatch repair_Homo sapiens_hsa03430 | 3.13869905 |
| 5 | Ribosome_Homo sapiens_hsa03010 | 3.04028374 |
| 6 | Parkinsons disease_Homo sapiens_hsa05012 | 3.04018843 |
| 7 | RNA polymerase_Homo sapiens_hsa03020 | 2.86174051 |
| 8 | DNA replication_Homo sapiens_hsa03030 | 2.83949513 |
| 9 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.69637620 |
| 10 | Homologous recombination_Homo sapiens_hsa03440 | 2.67154749 |
| 11 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.40218442 |
| 12 | Spliceosome_Homo sapiens_hsa03040 | 2.24245733 |
| 13 | Huntingtons disease_Homo sapiens_hsa05016 | 2.17963374 |
| 14 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.08115320 |
| 15 | Basal transcription factors_Homo sapiens_hsa03022 | 2.04212141 |
| 16 | RNA degradation_Homo sapiens_hsa03018 | 1.97530982 |
| 17 | RNA transport_Homo sapiens_hsa03013 | 1.95440264 |
| 18 | Alzheimers disease_Homo sapiens_hsa05010 | 1.91744735 |
| 19 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.85109766 |
| 20 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.77257806 |
| 21 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.75028440 |
| 22 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.74198200 |
| 23 | Base excision repair_Homo sapiens_hsa03410 | 1.65186524 |
| 24 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.63017146 |
| 25 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.50589444 |
| 26 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.50067966 |
| 27 | Cell cycle_Homo sapiens_hsa04110 | 1.39359912 |
| 28 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.31972620 |
| 29 | Purine metabolism_Homo sapiens_hsa00230 | 1.27409317 |
| 30 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.26133432 |
| 31 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.26072884 |
| 32 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.24600320 |
| 33 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.20335290 |
| 34 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.19716605 |
| 35 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.19615237 |
| 36 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.17583187 |
| 37 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.17304398 |
| 38 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.16884981 |
| 39 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.11781300 |
| 40 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.04180608 |
| 41 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.01582140 |
| 42 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.94696736 |
| 43 | Phototransduction_Homo sapiens_hsa04744 | 0.89121098 |
| 44 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.89092064 |
| 45 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.87117422 |
| 46 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.84816493 |
| 47 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.83420415 |
| 48 | Peroxisome_Homo sapiens_hsa04146 | 0.75486424 |
| 49 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.75410539 |
| 50 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.72461870 |
| 51 | Metabolic pathways_Homo sapiens_hsa01100 | 0.71136272 |
| 52 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.70245813 |
| 53 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.69652739 |
| 54 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.69650980 |
| 55 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.65657150 |
| 56 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.64628095 |
| 57 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.64197630 |
| 58 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.63347521 |
| 59 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.62565378 |
| 60 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.60726735 |
| 61 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.60024466 |
| 62 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.58573836 |
| 63 | Carbon metabolism_Homo sapiens_hsa01200 | 0.55490588 |
| 64 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.53554519 |
| 65 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.50364793 |
| 66 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.49810237 |
| 67 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.49757998 |
| 68 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.47769887 |
| 69 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.47655607 |
| 70 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.47329686 |
| 71 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.42157551 |
| 72 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.42131956 |
| 73 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.41447127 |
| 74 | Retinol metabolism_Homo sapiens_hsa00830 | 0.40895787 |
| 75 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.37466574 |
| 76 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.37085905 |
| 77 | Circadian rhythm_Homo sapiens_hsa04710 | 0.34930584 |
| 78 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.34008214 |
| 79 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.33981764 |
| 80 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.33329727 |
| 81 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.30971729 |
| 82 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.28591120 |
| 83 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.28133076 |
| 84 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.27981913 |
| 85 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.25208662 |
| 86 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.24376008 |
| 87 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.22789240 |
| 88 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.22754068 |
| 89 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.21775794 |
| 90 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.21477310 |
| 91 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.21089366 |
| 92 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.19878995 |
| 93 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.19708360 |
| 94 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.17931102 |
| 95 | Olfactory transduction_Homo sapiens_hsa04740 | 0.16771520 |
| 96 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.16771096 |
| 97 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.16386139 |
| 98 | Nicotine addiction_Homo sapiens_hsa05033 | 0.16244376 |
| 99 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.15941546 |
| 100 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.14160082 |

