

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | synaptic vesicle maturation (GO:0016188) | 7.34900505 |
| 2 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 6.94207027 |
| 3 | glutamate secretion (GO:0014047) | 6.43787831 |
| 4 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 6.34473937 |
| 5 | synaptic vesicle exocytosis (GO:0016079) | 6.09101617 |
| 6 | regulation of synaptic vesicle exocytosis (GO:2000300) | 5.69074951 |
| 7 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 5.44298558 |
| 8 | cellular potassium ion homeostasis (GO:0030007) | 5.44252318 |
| 9 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 5.39124071 |
| 10 | cerebellar granule cell differentiation (GO:0021707) | 5.31026540 |
| 11 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 5.27254923 |
| 12 | neuronal action potential propagation (GO:0019227) | 5.26420335 |
| 13 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 5.20144476 |
| 14 | regulation of synaptic vesicle transport (GO:1902803) | 5.02245827 |
| 15 | sodium ion export (GO:0071436) | 5.01455042 |
| 16 | neurotransmitter secretion (GO:0007269) | 4.86961840 |
| 17 | synaptic transmission, glutamatergic (GO:0035249) | 4.82762513 |
| 18 | vocalization behavior (GO:0071625) | 4.64023222 |
| 19 | postsynaptic membrane organization (GO:0001941) | 4.58874864 |
| 20 | protein localization to synapse (GO:0035418) | 4.58786092 |
| 21 | exploration behavior (GO:0035640) | 4.57968546 |
| 22 | neuron-neuron synaptic transmission (GO:0007270) | 4.56692456 |
| 23 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 4.46921843 |
| 24 | regulation of neuronal synaptic plasticity (GO:0048168) | 4.46444078 |
| 25 | glutamate receptor signaling pathway (GO:0007215) | 4.45499141 |
| 26 | locomotory exploration behavior (GO:0035641) | 4.45085847 |
| 27 | neuron cell-cell adhesion (GO:0007158) | 4.43768030 |
| 28 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 4.38180712 |
| 29 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 4.35209752 |
| 30 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 4.28794857 |
| 31 | layer formation in cerebral cortex (GO:0021819) | 4.25123293 |
| 32 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 4.15146645 |
| 33 | gamma-aminobutyric acid transport (GO:0015812) | 4.11864928 |
| 34 | regulation of glutamate receptor signaling pathway (GO:1900449) | 4.00941309 |
| 35 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 4.00351855 |
| 36 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 4.00275453 |
| 37 | positive regulation of synapse maturation (GO:0090129) | 3.97075215 |
| 38 | cerebellar Purkinje cell differentiation (GO:0021702) | 3.93428921 |
| 39 | neurotransmitter transport (GO:0006836) | 3.92685244 |
| 40 | regulation of dendritic spine morphogenesis (GO:0061001) | 3.92395410 |
| 41 | regulation of synapse structural plasticity (GO:0051823) | 3.90983946 |
| 42 | presynaptic membrane assembly (GO:0097105) | 3.90682131 |
| 43 | regulation of neurotransmitter secretion (GO:0046928) | 3.90427988 |
| 44 | negative regulation of dendrite morphogenesis (GO:0050774) | 3.90026626 |
| 45 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.89137158 |
| 46 | regulation of voltage-gated calcium channel activity (GO:1901385) | 3.85914603 |
| 47 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.84907429 |
| 48 | positive regulation of dendritic spine development (GO:0060999) | 3.82353139 |
| 49 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 3.81058326 |
| 50 | synaptic vesicle endocytosis (GO:0048488) | 3.80848132 |
| 51 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 3.80575406 |
| 52 | L-amino acid import (GO:0043092) | 3.78770169 |
| 53 | presynaptic membrane organization (GO:0097090) | 3.78120618 |
| 54 | regulation of postsynaptic membrane potential (GO:0060078) | 3.74046353 |
| 55 | regulation of synaptic plasticity (GO:0048167) | 3.73497011 |
| 56 | dendritic spine morphogenesis (GO:0060997) | 3.70018815 |
| 57 | membrane depolarization during action potential (GO:0086010) | 3.67366803 |
| 58 | regulation of vesicle fusion (GO:0031338) | 3.66455645 |
| 59 | cellular sodium ion homeostasis (GO:0006883) | 3.63034817 |
| 60 | axonal fasciculation (GO:0007413) | 3.60368726 |
| 61 | long-term memory (GO:0007616) | 3.58587760 |
| 62 | regulation of neurotransmitter levels (GO:0001505) | 3.55988227 |
| 63 | amino acid import (GO:0043090) | 3.55542103 |
| 64 | regulation of neurotransmitter transport (GO:0051588) | 3.54793456 |
| 65 | potassium ion homeostasis (GO:0055075) | 3.51833613 |
| 66 | membrane depolarization (GO:0051899) | 3.51431571 |
| 67 | neuronal ion channel clustering (GO:0045161) | 3.50604474 |
| 68 | positive regulation of membrane potential (GO:0045838) | 3.48577980 |
| 69 | transmission of nerve impulse (GO:0019226) | 3.47518511 |
| 70 | regulation of dendritic spine development (GO:0060998) | 3.47517091 |
| 71 | neuron recognition (GO:0008038) | 3.44995936 |
| 72 | cell communication by electrical coupling (GO:0010644) | 3.41928951 |
| 73 | detection of calcium ion (GO:0005513) | 3.39001582 |
| 74 | auditory behavior (GO:0031223) | 3.37793720 |
| 75 | serotonin metabolic process (GO:0042428) | 3.35064949 |
| 76 | positive regulation of neurotransmitter secretion (GO:0001956) | 3.32257334 |
| 77 | short-term memory (GO:0007614) | 3.30935690 |
| 78 | cell differentiation in hindbrain (GO:0021533) | 3.29674029 |
| 79 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 3.28977005 |
| 80 | cerebellar Purkinje cell layer development (GO:0021680) | 3.28893570 |
| 81 | neuromuscular synaptic transmission (GO:0007274) | 3.26098654 |
| 82 | neuromuscular process controlling balance (GO:0050885) | 3.25924509 |
| 83 | potassium ion import (GO:0010107) | 3.22816384 |
| 84 | positive regulation of neurotransmitter transport (GO:0051590) | 3.22507453 |
| 85 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 3.21772102 |
| 86 | C4-dicarboxylate transport (GO:0015740) | 3.20031777 |
| 87 | synaptic transmission (GO:0007268) | 3.19215800 |
| 88 | startle response (GO:0001964) | 3.16572440 |
| 89 | regulation of synaptic transmission (GO:0050804) | 3.16382069 |
| 90 | acidic amino acid transport (GO:0015800) | 3.13365269 |
| 91 | regulation of synapse maturation (GO:0090128) | 3.07660665 |
| 92 | adult walking behavior (GO:0007628) | 3.04369817 |
| 93 | prepulse inhibition (GO:0060134) | 3.04100129 |
| 94 | regulation of dendrite morphogenesis (GO:0048814) | 3.03340960 |
| 95 | long-term synaptic potentiation (GO:0060291) | 3.02177032 |
| 96 | proline transport (GO:0015824) | 3.00459857 |
| 97 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 2.99965186 |
| 98 | dendritic spine organization (GO:0097061) | 2.99951702 |
| 99 | establishment of mitochondrion localization (GO:0051654) | 2.98754018 |
| 100 | response to histamine (GO:0034776) | 2.97928677 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 6.02691917 |
| 2 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 3.80505613 |
| 3 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.48846559 |
| 4 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 3.24721783 |
| 5 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 3.10088398 |
| 6 | REST_21632747_ChIP-Seq_MESCs_Mouse | 3.07871711 |
| 7 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 3.07209723 |
| 8 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.66923703 |
| 9 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.66923703 |
| 10 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.62166473 |
| 11 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.60197290 |
| 12 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.59407838 |
| 13 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.58527849 |
| 14 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.54515946 |
| 15 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.52909064 |
| 16 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.51406788 |
| 17 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.50022856 |
| 18 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.46479652 |
| 19 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.43433791 |
| 20 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 2.41644882 |
| 21 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.35736871 |
| 22 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.33825379 |
| 23 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.21205097 |
| 24 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.21056010 |
| 25 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.20573116 |
| 26 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.93724289 |
| 27 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.93115348 |
| 28 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.91473114 |
| 29 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.88734252 |
| 30 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.74951625 |
| 31 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.70749043 |
| 32 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.70460763 |
| 33 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.67618132 |
| 34 | * CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.63510810 |
| 35 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.55891795 |
| 36 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.53183448 |
| 37 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.53061097 |
| 38 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.52837703 |
| 39 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.49513472 |
| 40 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.47807512 |
| 41 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.47320093 |
| 42 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.44151243 |
| 43 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.43102581 |
| 44 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.42309733 |
| 45 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.41193760 |
| 46 | * CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.41048569 |
| 47 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.35195323 |
| 48 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.33643617 |
| 49 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.31382228 |
| 50 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.27014102 |
| 51 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.24275848 |
| 52 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.23962932 |
| 53 | P300_19829295_ChIP-Seq_ESCs_Human | 1.23182471 |
| 54 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.21507267 |
| 55 | * SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.19965740 |
| 56 | * SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.19789967 |
| 57 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.16232704 |
| 58 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.15861224 |
| 59 | AR_19668381_ChIP-Seq_PC3_Human | 1.14172620 |
| 60 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.14084210 |
| 61 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.12470574 |
| 62 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.12280366 |
| 63 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.11169431 |
| 64 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.10376551 |
| 65 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.09786841 |
| 66 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.09602379 |
| 67 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.09602379 |
| 68 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.08515974 |
| 69 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.08250944 |
| 70 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.07656181 |
| 71 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.04380895 |
| 72 | TCF4_23295773_ChIP-Seq_U87_Human | 1.03527644 |
| 73 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.03466640 |
| 74 | * AR_25329375_ChIP-Seq_VCAP_Human | 1.03310782 |
| 75 | STAT3_23295773_ChIP-Seq_U87_Human | 1.02704629 |
| 76 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.02187779 |
| 77 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.01253693 |
| 78 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 0.99466328 |
| 79 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.98662647 |
| 80 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.98522711 |
| 81 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.98120775 |
| 82 | SOX9_26525672_Chip-Seq_HEART_Mouse | 0.97933652 |
| 83 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.96662080 |
| 84 | FUS_26573619_Chip-Seq_HEK293_Human | 0.96627171 |
| 85 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.95400290 |
| 86 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 0.92294957 |
| 87 | JUN_21703547_ChIP-Seq_K562_Human | 0.92127348 |
| 88 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.91993228 |
| 89 | TP53_18474530_ChIP-ChIP_U2OS_Human | 0.91802595 |
| 90 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.91759882 |
| 91 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 0.91324482 |
| 92 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 0.91226994 |
| 93 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.90557351 |
| 94 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.89890936 |
| 95 | KDM2B_26808549_Chip-Seq_REH_Human | 0.86989942 |
| 96 | VDR_22108803_ChIP-Seq_LS180_Human | 0.86446753 |
| 97 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.86281018 |
| 98 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 0.86108166 |
| 99 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.85940668 |
| 100 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.85307748 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0004859_abnormal_synaptic_plasticity | 6.46669669 |
| 2 | MP0003880_abnormal_central_pattern | 5.40227165 |
| 3 | MP0004270_analgesia | 4.34792962 |
| 4 | MP0003635_abnormal_synaptic_transmissio | 4.10789771 |
| 5 | MP0009046_muscle_twitch | 3.56162759 |
| 6 | MP0002064_seizures | 3.52717408 |
| 7 | MP0009745_abnormal_behavioral_response | 3.39982904 |
| 8 | MP0002063_abnormal_learning/memory/cond | 3.31941856 |
| 9 | MP0002272_abnormal_nervous_system | 3.24881049 |
| 10 | MP0005423_abnormal_somatic_nervous | 3.07098874 |
| 11 | MP0001968_abnormal_touch/_nociception | 2.97060194 |
| 12 | MP0001486_abnormal_startle_reflex | 2.93344063 |
| 13 | MP0002734_abnormal_mechanical_nocicepti | 2.86638346 |
| 14 | MP0002572_abnormal_emotion/affect_behav | 2.79310408 |
| 15 | MP0002735_abnormal_chemical_nociception | 2.65210181 |
| 16 | MP0001501_abnormal_sleep_pattern | 2.36895619 |
| 17 | MP0008569_lethality_at_weaning | 2.34461828 |
| 18 | MP0002736_abnormal_nociception_after | 2.32021544 |
| 19 | MP0002822_catalepsy | 2.16942445 |
| 20 | MP0002067_abnormal_sensory_capabilities | 2.05067418 |
| 21 | MP0003879_abnormal_hair_cell | 2.04324883 |
| 22 | MP0001970_abnormal_pain_threshold | 2.01782718 |
| 23 | MP0000778_abnormal_nervous_system | 1.97788833 |
| 24 | MP0002733_abnormal_thermal_nociception | 1.93231121 |
| 25 | MP0001440_abnormal_grooming_behavior | 1.91833295 |
| 26 | MP0001984_abnormal_olfaction | 1.79703955 |
| 27 | MP0003787_abnormal_imprinting | 1.79516924 |
| 28 | MP0004742_abnormal_vestibular_system | 1.78624680 |
| 29 | MP0003329_amyloid_beta_deposits | 1.77455923 |
| 30 | MP0004811_abnormal_neuron_physiology | 1.73402871 |
| 31 | MP0006276_abnormal_autonomic_nervous | 1.67916807 |
| 32 | MP0002557_abnormal_social/conspecific_i | 1.67665538 |
| 33 | MP0004924_abnormal_behavior | 1.66899765 |
| 34 | MP0005386_behavior/neurological_phenoty | 1.66899765 |
| 35 | MP0003122_maternal_imprinting | 1.53021672 |
| 36 | MP0002184_abnormal_innervation | 1.51877352 |
| 37 | MP0002066_abnormal_motor_capabilities/c | 1.51807835 |
| 38 | MP0002882_abnormal_neuron_morphology | 1.50815766 |
| 39 | MP0010386_abnormal_urinary_bladder | 1.50676325 |
| 40 | MP0003633_abnormal_nervous_system | 1.47250541 |
| 41 | MP0005646_abnormal_pituitary_gland | 1.45466326 |
| 42 | MP0000955_abnormal_spinal_cord | 1.39420235 |
| 43 | MP0001905_abnormal_dopamine_level | 1.30989766 |
| 44 | MP0004885_abnormal_endolymph | 1.30745157 |
| 45 | MP0001177_atelectasis | 1.28934051 |
| 46 | MP0003631_nervous_system_phenotype | 1.23690353 |
| 47 | MP0001529_abnormal_vocalization | 1.20435731 |
| 48 | MP0002152_abnormal_brain_morphology | 1.18758680 |
| 49 | MP0000569_abnormal_digit_pigmentation | 1.17601582 |
| 50 | MP0001502_abnormal_circadian_rhythm | 1.17248539 |
| 51 | MP0000920_abnormal_myelination | 1.17026239 |
| 52 | MP0002638_abnormal_pupillary_reflex | 1.15165972 |
| 53 | MP0003690_abnormal_glial_cell | 1.03581129 |
| 54 | MP0002229_neurodegeneration | 1.01436328 |
| 55 | MP0008874_decreased_physiological_sensi | 0.97727757 |
| 56 | MP0009780_abnormal_chondrocyte_physiolo | 0.95111834 |
| 57 | MP0003123_paternal_imprinting | 0.93529566 |
| 58 | MP0005623_abnormal_meninges_morphology | 0.92242744 |
| 59 | MP0001963_abnormal_hearing_physiology | 0.91212264 |
| 60 | MP0005551_abnormal_eye_electrophysiolog | 0.89640978 |
| 61 | MP0001485_abnormal_pinna_reflex | 0.84765326 |
| 62 | MP0003634_abnormal_glial_cell | 0.84060007 |
| 63 | MP0003632_abnormal_nervous_system | 0.81491144 |
| 64 | MP0002752_abnormal_somatic_nervous | 0.81297122 |
| 65 | MP0004142_abnormal_muscle_tone | 0.81119472 |
| 66 | MP0001188_hyperpigmentation | 0.80162222 |
| 67 | MP0002909_abnormal_adrenal_gland | 0.77017877 |
| 68 | MP0002069_abnormal_eating/drinking_beha | 0.76380516 |
| 69 | MP0003121_genomic_imprinting | 0.75539214 |
| 70 | MP0008872_abnormal_physiological_respon | 0.74411762 |
| 71 | MP0008877_abnormal_DNA_methylation | 0.71320394 |
| 72 | MP0003137_abnormal_impulse_conducting | 0.71286547 |
| 73 | MP0000566_synostosis | 0.70828187 |
| 74 | MP0000604_amyloidosis | 0.70664560 |
| 75 | MP0004147_increased_porphyrin_level | 0.68777007 |
| 76 | MP0003861_abnormal_nervous_system | 0.65784651 |
| 77 | MP0001299_abnormal_eye_distance/ | 0.65581154 |
| 78 | MP0000026_abnormal_inner_ear | 0.65236641 |
| 79 | MP0001346_abnormal_lacrimal_gland | 0.62983579 |
| 80 | MP0010769_abnormal_survival | 0.61036399 |
| 81 | MP0002082_postnatal_lethality | 0.59754723 |
| 82 | MP0010770_preweaning_lethality | 0.59754723 |
| 83 | MP0005535_abnormal_body_temperature | 0.58356176 |
| 84 | MP0010768_mortality/aging | 0.57654819 |
| 85 | MP0000631_abnormal_neuroendocrine_gland | 0.57391076 |
| 86 | MP0004085_abnormal_heartbeat | 0.55720926 |
| 87 | MP0003938_abnormal_ear_development | 0.53072077 |
| 88 | MP0005187_abnormal_penis_morphology | 0.52579806 |
| 89 | MP0005394_taste/olfaction_phenotype | 0.51296775 |
| 90 | MP0005499_abnormal_olfactory_system | 0.51296775 |
| 91 | MP0001986_abnormal_taste_sensitivity | 0.51149704 |
| 92 | MP0003956_abnormal_body_size | 0.50809109 |
| 93 | MP0005167_abnormal_blood-brain_barrier | 0.49667784 |
| 94 | MP0001943_abnormal_respiration | 0.49402525 |
| 95 | MP0002102_abnormal_ear_morphology | 0.49145392 |
| 96 | MP0004215_abnormal_myocardial_fiber | 0.48345914 |
| 97 | MP0005645_abnormal_hypothalamus_physiol | 0.47834467 |
| 98 | MP0003283_abnormal_digestive_organ | 0.45420924 |
| 99 | MP0000579_abnormal_nail_morphology | 0.42790363 |
| 100 | MP0006292_abnormal_olfactory_placode | 0.40828787 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Focal motor seizures (HP:0011153) | 8.95090177 |
| 2 | Myokymia (HP:0002411) | 8.14267340 |
| 3 | Febrile seizures (HP:0002373) | 7.44597455 |
| 4 | Atonic seizures (HP:0010819) | 7.41934643 |
| 5 | Focal seizures (HP:0007359) | 6.77675500 |
| 6 | Action tremor (HP:0002345) | 6.34593932 |
| 7 | Epileptic encephalopathy (HP:0200134) | 6.05972564 |
| 8 | Absence seizures (HP:0002121) | 5.04930497 |
| 9 | Progressive cerebellar ataxia (HP:0002073) | 4.69344094 |
| 10 | Dialeptic seizures (HP:0011146) | 4.61887305 |
| 11 | Generalized tonic-clonic seizures (HP:0002069) | 4.49526426 |
| 12 | Supranuclear gaze palsy (HP:0000605) | 3.94111663 |
| 13 | Impaired vibration sensation in the lower limbs (HP:0002166) | 3.90971267 |
| 14 | Diplopia (HP:0000651) | 3.82452402 |
| 15 | Abnormality of binocular vision (HP:0011514) | 3.82452402 |
| 16 | Truncal ataxia (HP:0002078) | 3.77340540 |
| 17 | Limb dystonia (HP:0002451) | 3.66382241 |
| 18 | Ankle clonus (HP:0011448) | 3.59316338 |
| 19 | Dysmetria (HP:0001310) | 3.45494274 |
| 20 | Dysdiadochokinesis (HP:0002075) | 3.43443396 |
| 21 | Scanning speech (HP:0002168) | 3.42959389 |
| 22 | Spastic gait (HP:0002064) | 3.40621525 |
| 23 | Broad-based gait (HP:0002136) | 3.37351350 |
| 24 | Intention tremor (HP:0002080) | 3.29558233 |
| 25 | Abnormal eating behavior (HP:0100738) | 3.26001086 |
| 26 | Mutism (HP:0002300) | 3.22579095 |
| 27 | Torticollis (HP:0000473) | 3.20051291 |
| 28 | Status epilepticus (HP:0002133) | 3.12709536 |
| 29 | Gaze-evoked nystagmus (HP:0000640) | 3.12137453 |
| 30 | Epileptiform EEG discharges (HP:0011182) | 3.04094808 |
| 31 | Urinary bladder sphincter dysfunction (HP:0002839) | 3.03797437 |
| 32 | Postural instability (HP:0002172) | 2.98362751 |
| 33 | Neurofibrillary tangles (HP:0002185) | 2.96773369 |
| 34 | Abnormality of the corticospinal tract (HP:0002492) | 2.95866480 |
| 35 | Urinary urgency (HP:0000012) | 2.94895323 |
| 36 | Amblyopia (HP:0000646) | 2.92623521 |
| 37 | Hemiplegia (HP:0002301) | 2.92591200 |
| 38 | Focal dystonia (HP:0004373) | 2.92014103 |
| 39 | Papilledema (HP:0001085) | 2.86361334 |
| 40 | Visual hallucinations (HP:0002367) | 2.84869616 |
| 41 | Poor eye contact (HP:0000817) | 2.81440591 |
| 42 | Drooling (HP:0002307) | 2.76201353 |
| 43 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.73621906 |
| 44 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.73621906 |
| 45 | Hemiparesis (HP:0001269) | 2.71181992 |
| 46 | Hyperventilation (HP:0002883) | 2.70253117 |
| 47 | EEG with generalized epileptiform discharges (HP:0011198) | 2.67554512 |
| 48 | Depression (HP:0000716) | 2.66084509 |
| 49 | Excessive salivation (HP:0003781) | 2.54995068 |
| 50 | Lower limb muscle weakness (HP:0007340) | 2.53410466 |
| 51 | Impaired smooth pursuit (HP:0007772) | 2.53164741 |
| 52 | Dysmetric saccades (HP:0000641) | 2.52746850 |
| 53 | Impaired vibratory sensation (HP:0002495) | 2.50842834 |
| 54 | Polyphagia (HP:0002591) | 2.46665161 |
| 55 | Delusions (HP:0000746) | 2.44850197 |
| 56 | Abnormality of the lower motor neuron (HP:0002366) | 2.44188682 |
| 57 | Craniofacial dystonia (HP:0012179) | 2.43204746 |
| 58 | Hypsarrhythmia (HP:0002521) | 2.41169103 |
| 59 | Anxiety (HP:0000739) | 2.41124878 |
| 60 | Akinesia (HP:0002304) | 2.38659945 |
| 61 | Abnormal social behavior (HP:0012433) | 2.37986985 |
| 62 | Impaired social interactions (HP:0000735) | 2.37986985 |
| 63 | Cerebral inclusion bodies (HP:0100314) | 2.36821335 |
| 64 | Annular pancreas (HP:0001734) | 2.36158479 |
| 65 | Bradykinesia (HP:0002067) | 2.31141131 |
| 66 | Abnormality of ocular smooth pursuit (HP:0000617) | 2.24832017 |
| 67 | Sleep apnea (HP:0010535) | 2.23937405 |
| 68 | Neuronal loss in central nervous system (HP:0002529) | 2.22436882 |
| 69 | Cerebral hypomyelination (HP:0006808) | 2.18395733 |
| 70 | Morphological abnormality of the pyramidal tract (HP:0002062) | 2.16535180 |
| 71 | Obstructive sleep apnea (HP:0002870) | 2.12772556 |
| 72 | Tetraplegia (HP:0002445) | 2.12329215 |
| 73 | Postural tremor (HP:0002174) | 2.08645058 |
| 74 | Gait ataxia (HP:0002066) | 2.07890254 |
| 75 | Absent speech (HP:0001344) | 2.05394536 |
| 76 | Clonus (HP:0002169) | 2.03114371 |
| 77 | Incomplete penetrance (HP:0003829) | 2.01446020 |
| 78 | Split foot (HP:0001839) | 1.98884099 |
| 79 | Apathy (HP:0000741) | 1.97650523 |
| 80 | Abnormality of saccadic eye movements (HP:0000570) | 1.92093677 |
| 81 | Insomnia (HP:0100785) | 1.87196521 |
| 82 | Spastic tetraplegia (HP:0002510) | 1.87059942 |
| 83 | Stereotypic behavior (HP:0000733) | 1.84752533 |
| 84 | Esotropia (HP:0000565) | 1.83843841 |
| 85 | Megalencephaly (HP:0001355) | 1.81554198 |
| 86 | Diminished motivation (HP:0000745) | 1.79434361 |
| 87 | Amyotrophic lateral sclerosis (HP:0007354) | 1.76101918 |
| 88 | Rigidity (HP:0002063) | 1.73850745 |
| 89 | Heterochromia iridis (HP:0001100) | 1.69777930 |
| 90 | Aplasia involving bones of the extremities (HP:0009825) | 1.68014596 |
| 91 | Aplasia involving bones of the upper limbs (HP:0009823) | 1.68014596 |
| 92 | Aplasia of the phalanges of the hand (HP:0009802) | 1.68014596 |
| 93 | Inability to walk (HP:0002540) | 1.67962433 |
| 94 | Generalized myoclonic seizures (HP:0002123) | 1.65781514 |
| 95 | Hammertoe (HP:0001765) | 1.65230367 |
| 96 | Peripheral hypomyelination (HP:0007182) | 1.64398004 |
| 97 | Rapidly progressive (HP:0003678) | 1.64094471 |
| 98 | Memory impairment (HP:0002354) | 1.63089754 |
| 99 | Limb ataxia (HP:0002070) | 1.60363345 |
| 100 | Hypoplasia of the corpus callosum (HP:0002079) | 1.57397123 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EPHA4 | 5.68759933 |
| 2 | MARK1 | 4.63992290 |
| 3 | NTRK3 | 4.08756618 |
| 4 | CASK | 3.38241434 |
| 5 | PAK6 | 3.17848926 |
| 6 | DAPK2 | 3.12784138 |
| 7 | MAP3K9 | 2.70354076 |
| 8 | NTRK2 | 2.62642126 |
| 9 | MINK1 | 2.27635164 |
| 10 | NTRK1 | 2.22108988 |
| 11 | UHMK1 | 2.12398668 |
| 12 | CAMKK1 | 2.05309764 |
| 13 | MAPK13 | 1.89767792 |
| 14 | PLK2 | 1.88797336 |
| 15 | GRK5 | 1.83347051 |
| 16 | SIK2 | 1.82374189 |
| 17 | LATS2 | 1.79672553 |
| 18 | PRKD3 | 1.69864222 |
| 19 | PINK1 | 1.66948999 |
| 20 | CDK5 | 1.61869484 |
| 21 | PRKCG | 1.55494619 |
| 22 | CDK19 | 1.51548237 |
| 23 | CAMKK2 | 1.42568017 |
| 24 | MAP3K4 | 1.41240050 |
| 25 | ARAF | 1.41036028 |
| 26 | DAPK1 | 1.37896222 |
| 27 | MAP3K12 | 1.26624512 |
| 28 | CAMK2B | 1.21257218 |
| 29 | CAMK1 | 1.18836996 |
| 30 | TNIK | 1.18790543 |
| 31 | CAMK2A | 1.15515065 |
| 32 | CDK15 | 1.11618923 |
| 33 | CDK18 | 1.10732773 |
| 34 | PHKG2 | 1.09665446 |
| 35 | PHKG1 | 1.09665446 |
| 36 | PAK3 | 1.09363542 |
| 37 | MAP2K7 | 1.08838642 |
| 38 | RIPK4 | 1.06086037 |
| 39 | CDK14 | 1.04834464 |
| 40 | CDK11A | 1.01605865 |
| 41 | CSNK1G2 | 1.01456729 |
| 42 | TYRO3 | 1.01415202 |
| 43 | PRKCH | 0.98635953 |
| 44 | SGK223 | 0.98616026 |
| 45 | SGK494 | 0.98616026 |
| 46 | KSR2 | 0.98493879 |
| 47 | KSR1 | 0.89602216 |
| 48 | CCNB1 | 0.87492709 |
| 49 | DYRK1A | 0.85549746 |
| 50 | PNCK | 0.85152121 |
| 51 | MAP2K4 | 0.79222081 |
| 52 | LIMK1 | 0.75682656 |
| 53 | STK11 | 0.70679036 |
| 54 | SGK1 | 0.70414905 |
| 55 | OXSR1 | 0.70322523 |
| 56 | STK38 | 0.69988457 |
| 57 | SGK2 | 0.68521666 |
| 58 | MARK2 | 0.66934779 |
| 59 | CAMK4 | 0.63095717 |
| 60 | CAMK2G | 0.62196023 |
| 61 | DYRK2 | 0.62194182 |
| 62 | TESK1 | 0.61980832 |
| 63 | PKN1 | 0.61519874 |
| 64 | PRKCE | 0.60833141 |
| 65 | ALK | 0.58876092 |
| 66 | NEK6 | 0.58009944 |
| 67 | PRKCZ | 0.57047262 |
| 68 | MAPK12 | 0.56716806 |
| 69 | ROCK2 | 0.56307580 |
| 70 | RPS6KA3 | 0.54606026 |
| 71 | MAPK10 | 0.53905904 |
| 72 | CAMK1G | 0.51164924 |
| 73 | BRSK1 | 0.50919391 |
| 74 | RAF1 | 0.50236030 |
| 75 | PDK1 | 0.50069756 |
| 76 | DAPK3 | 0.49929839 |
| 77 | FYN | 0.49562032 |
| 78 | MAP4K2 | 0.48552691 |
| 79 | BCR | 0.46608874 |
| 80 | PRKG1 | 0.46071184 |
| 81 | SGK3 | 0.45610922 |
| 82 | CSNK1G3 | 0.45417473 |
| 83 | EPHB2 | 0.44740196 |
| 84 | MAP3K13 | 0.44186688 |
| 85 | CSNK1A1L | 0.43871458 |
| 86 | ADRBK2 | 0.43425515 |
| 87 | RIPK1 | 0.43331092 |
| 88 | MAP3K11 | 0.42675081 |
| 89 | BMPR2 | 0.40817669 |
| 90 | CAMK2D | 0.38752862 |
| 91 | PRKCA | 0.37215715 |
| 92 | BRAF | 0.35228106 |
| 93 | ROCK1 | 0.34272437 |
| 94 | WNK1 | 0.34062960 |
| 95 | MOS | 0.33681929 |
| 96 | TAOK1 | 0.33313958 |
| 97 | WNK3 | 0.32988032 |
| 98 | CSNK1D | 0.32317877 |
| 99 | PRKACA | 0.31219401 |
| 100 | CAMK1D | 0.31000166 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Nicotine addiction_Homo sapiens_hsa05033 | 4.73717184 |
| 2 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 3.47483350 |
| 3 | GABAergic synapse_Homo sapiens_hsa04727 | 3.20781771 |
| 4 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 3.09640288 |
| 5 | Morphine addiction_Homo sapiens_hsa05032 | 2.98448109 |
| 6 | Long-term potentiation_Homo sapiens_hsa04720 | 2.93582072 |
| 7 | Circadian entrainment_Homo sapiens_hsa04713 | 2.91748015 |
| 8 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.90373111 |
| 9 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.78513867 |
| 10 | Dopaminergic synapse_Homo sapiens_hsa04728 | 2.43340823 |
| 11 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 2.38959950 |
| 12 | Insulin secretion_Homo sapiens_hsa04911 | 2.25484739 |
| 13 | Gastric acid secretion_Homo sapiens_hsa04971 | 2.08801000 |
| 14 | Cholinergic synapse_Homo sapiens_hsa04725 | 2.04122975 |
| 15 | Cocaine addiction_Homo sapiens_hsa05030 | 2.03328936 |
| 16 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.99376425 |
| 17 | Salivary secretion_Homo sapiens_hsa04970 | 1.89357706 |
| 18 | Long-term depression_Homo sapiens_hsa04730 | 1.82487348 |
| 19 | Taste transduction_Homo sapiens_hsa04742 | 1.76151987 |
| 20 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.75062647 |
| 21 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.59046774 |
| 22 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.56545326 |
| 23 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.55055403 |
| 24 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.50567492 |
| 25 | Renin secretion_Homo sapiens_hsa04924 | 1.45834332 |
| 26 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.40467502 |
| 27 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.39170810 |
| 28 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.36625087 |
| 29 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 1.35237392 |
| 30 | Gap junction_Homo sapiens_hsa04540 | 1.34992217 |
| 31 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.24638771 |
| 32 | Olfactory transduction_Homo sapiens_hsa04740 | 1.20485846 |
| 33 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.19733377 |
| 34 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.15923811 |
| 35 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.12767662 |
| 36 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.12567769 |
| 37 | Pancreatic secretion_Homo sapiens_hsa04972 | 1.06535439 |
| 38 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.04917260 |
| 39 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.01537895 |
| 40 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.01135310 |
| 41 | Glioma_Homo sapiens_hsa05214 | 1.00701972 |
| 42 | Melanogenesis_Homo sapiens_hsa04916 | 0.99927992 |
| 43 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.97983215 |
| 44 | Axon guidance_Homo sapiens_hsa04360 | 0.95231119 |
| 45 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.94513566 |
| 46 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.92694297 |
| 47 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.83216834 |
| 48 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.83215621 |
| 49 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.78824766 |
| 50 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.78791565 |
| 51 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.77101464 |
| 52 | Phototransduction_Homo sapiens_hsa04744 | 0.76105278 |
| 53 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.73920027 |
| 54 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.72525085 |
| 55 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.72250724 |
| 56 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.71260134 |
| 57 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.70185087 |
| 58 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.67513341 |
| 59 | Alzheimers disease_Homo sapiens_hsa05010 | 0.66005645 |
| 60 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.63711988 |
| 61 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.63568815 |
| 62 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.60415539 |
| 63 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.59091774 |
| 64 | Prion diseases_Homo sapiens_hsa05020 | 0.55460966 |
| 65 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.50255030 |
| 66 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.49555302 |
| 67 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.49471027 |
| 68 | Circadian rhythm_Homo sapiens_hsa04710 | 0.47878377 |
| 69 | Bile secretion_Homo sapiens_hsa04976 | 0.47416973 |
| 70 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.47413955 |
| 71 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.45694454 |
| 72 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.44946390 |
| 73 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.42363084 |
| 74 | Alcoholism_Homo sapiens_hsa05034 | 0.41925852 |
| 75 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.41859109 |
| 76 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.41643402 |
| 77 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.41624031 |
| 78 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.41513848 |
| 79 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.40401741 |
| 80 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.39182405 |
| 81 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.37975381 |
| 82 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.36558783 |
| 83 | Endocytosis_Homo sapiens_hsa04144 | 0.34924036 |
| 84 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.29881672 |
| 85 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.28325423 |
| 86 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.26279909 |
| 87 | Tight junction_Homo sapiens_hsa04530 | 0.25894580 |
| 88 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.25442253 |
| 89 | Parkinsons disease_Homo sapiens_hsa05012 | 0.23738002 |
| 90 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.23040584 |
| 91 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.21885119 |
| 92 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.18488117 |
| 93 | Mineral absorption_Homo sapiens_hsa04978 | 0.17598041 |
| 94 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.17209104 |
| 95 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.12353035 |
| 96 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.12303881 |
| 97 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.11898715 |
| 98 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.11155518 |
| 99 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.10526160 |
| 100 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.09925605 |

