

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 7.36860764 |
| 2 | ATP synthesis coupled proton transport (GO:0015986) | 6.37368707 |
| 3 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 6.37368707 |
| 4 | chaperone-mediated protein transport (GO:0072321) | 6.21014066 |
| 5 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 6.15309240 |
| 6 | ribosomal small subunit assembly (GO:0000028) | 5.77541249 |
| 7 | viral transcription (GO:0019083) | 5.50679463 |
| 8 | ribosomal small subunit biogenesis (GO:0042274) | 5.43122241 |
| 9 | translational termination (GO:0006415) | 5.36664096 |
| 10 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 5.32103820 |
| 11 | proteasome assembly (GO:0043248) | 5.30464345 |
| 12 | respiratory electron transport chain (GO:0022904) | 5.24720845 |
| 13 | maturation of SSU-rRNA (GO:0030490) | 5.24130626 |
| 14 | electron transport chain (GO:0022900) | 5.14248057 |
| 15 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 5.06840106 |
| 16 | cotranslational protein targeting to membrane (GO:0006613) | 5.01143283 |
| 17 | protein targeting to ER (GO:0045047) | 4.98550531 |
| 18 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.79792593 |
| 19 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.76177951 |
| 20 | protein localization to endoplasmic reticulum (GO:0070972) | 4.70332762 |
| 21 | translational elongation (GO:0006414) | 4.65970351 |
| 22 | termination of RNA polymerase III transcription (GO:0006386) | 4.64928931 |
| 23 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 4.64928931 |
| 24 | protein complex biogenesis (GO:0070271) | 4.52573369 |
| 25 | regulation of mitochondrial translation (GO:0070129) | 4.48334348 |
| 26 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 4.40786247 |
| 27 | negative regulation of ligase activity (GO:0051352) | 4.40786247 |
| 28 | ribosomal large subunit biogenesis (GO:0042273) | 4.39554504 |
| 29 | establishment of integrated proviral latency (GO:0075713) | 4.38003238 |
| 30 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 4.34991843 |
| 31 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.33290509 |
| 32 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 4.33027602 |
| 33 | translational initiation (GO:0006413) | 4.30589836 |
| 34 | translation (GO:0006412) | 4.29597707 |
| 35 | rRNA modification (GO:0000154) | 4.23925646 |
| 36 | viral life cycle (GO:0019058) | 4.23337170 |
| 37 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.23027597 |
| 38 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.18587158 |
| 39 | NADH dehydrogenase complex assembly (GO:0010257) | 4.18587158 |
| 40 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.18587158 |
| 41 | regulation of cellular amino acid metabolic process (GO:0006521) | 4.18319076 |
| 42 | cellular protein complex disassembly (GO:0043624) | 4.15203274 |
| 43 | protein neddylation (GO:0045116) | 4.12280358 |
| 44 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 4.11751763 |
| 45 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 4.02616870 |
| 46 | respiratory chain complex IV assembly (GO:0008535) | 3.96541008 |
| 47 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.94767713 |
| 48 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.94689972 |
| 49 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.94689972 |
| 50 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.94689972 |
| 51 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.94001331 |
| 52 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.94001331 |
| 53 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.93219323 |
| 54 | protein targeting to mitochondrion (GO:0006626) | 3.92430690 |
| 55 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.82369101 |
| 56 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.82369101 |
| 57 | pseudouridine synthesis (GO:0001522) | 3.78410095 |
| 58 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.77329904 |
| 59 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.75908282 |
| 60 | establishment of viral latency (GO:0019043) | 3.74443645 |
| 61 | cytochrome complex assembly (GO:0017004) | 3.74200946 |
| 62 | establishment of protein localization to mitochondrion (GO:0072655) | 3.74092509 |
| 63 | spliceosomal snRNP assembly (GO:0000387) | 3.71559143 |
| 64 | cellular component biogenesis (GO:0044085) | 3.70950523 |
| 65 | chromatin remodeling at centromere (GO:0031055) | 3.70846124 |
| 66 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.69224200 |
| 67 | rRNA processing (GO:0006364) | 3.64836698 |
| 68 | protein localization to mitochondrion (GO:0070585) | 3.63961903 |
| 69 | CENP-A containing nucleosome assembly (GO:0034080) | 3.62864740 |
| 70 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.61989690 |
| 71 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.61989690 |
| 72 | DNA deamination (GO:0045006) | 3.61360989 |
| 73 | positive regulation of ligase activity (GO:0051351) | 3.58661334 |
| 74 | protein complex disassembly (GO:0043241) | 3.56860947 |
| 75 | inner mitochondrial membrane organization (GO:0007007) | 3.54150457 |
| 76 | rRNA metabolic process (GO:0016072) | 3.50029470 |
| 77 | ATP biosynthetic process (GO:0006754) | 3.48186476 |
| 78 | macromolecular complex disassembly (GO:0032984) | 3.41376467 |
| 79 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 3.41371851 |
| 80 | hydrogen ion transmembrane transport (GO:1902600) | 3.40831090 |
| 81 | oxidative phosphorylation (GO:0006119) | 3.35357109 |
| 82 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.34951354 |
| 83 | protein targeting to membrane (GO:0006612) | 3.31983305 |
| 84 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.31456649 |
| 85 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.30716352 |
| 86 | rRNA methylation (GO:0031167) | 3.28819792 |
| 87 | regulation of ligase activity (GO:0051340) | 3.28317738 |
| 88 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.25139769 |
| 89 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.22406215 |
| 90 | protein-cofactor linkage (GO:0018065) | 3.22388900 |
| 91 | 7-methylguanosine mRNA capping (GO:0006370) | 3.22332720 |
| 92 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.17617662 |
| 93 | mRNA catabolic process (GO:0006402) | 3.15752378 |
| 94 | nucleobase biosynthetic process (GO:0046112) | 3.15710864 |
| 95 | purine nucleobase biosynthetic process (GO:0009113) | 3.15214071 |
| 96 | regulation of cellular amine metabolic process (GO:0033238) | 3.14733322 |
| 97 | RNA capping (GO:0036260) | 3.13938936 |
| 98 | 7-methylguanosine RNA capping (GO:0009452) | 3.13938936 |
| 99 | DNA damage response, detection of DNA damage (GO:0042769) | 3.13782409 |
| 100 | mitochondrial transport (GO:0006839) | 3.13472561 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.37294147 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.79483636 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 4.43252274 |
| 4 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.19764616 |
| 5 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.97573162 |
| 6 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.71854838 |
| 7 | E2F7_22180533_ChIP-Seq_HELA_Human | 3.70028502 |
| 8 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.61620684 |
| 9 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.60707024 |
| 10 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.40133016 |
| 11 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 3.31372138 |
| 12 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 3.26236465 |
| 13 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.16095366 |
| 14 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 3.07276162 |
| 15 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.01663830 |
| 16 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.98995158 |
| 17 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.89702301 |
| 18 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.82177727 |
| 19 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.80127009 |
| 20 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.62506952 |
| 21 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.55431250 |
| 22 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.51523827 |
| 23 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.50706506 |
| 24 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.49218307 |
| 25 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.48684954 |
| 26 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.44004798 |
| 27 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.25413867 |
| 28 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.25308442 |
| 29 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.20920167 |
| 30 | TTF2_22483619_ChIP-Seq_HELA_Human | 2.20794514 |
| 31 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.20156898 |
| 32 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.15997657 |
| 33 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 2.14388554 |
| 34 | GABP_19822575_ChIP-Seq_HepG2_Human | 2.12192200 |
| 35 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.08074582 |
| 36 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.86889254 |
| 37 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.80269725 |
| 38 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.68042247 |
| 39 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.67639737 |
| 40 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.66035323 |
| 41 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.61676468 |
| 42 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.59302830 |
| 43 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.58822359 |
| 44 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.56450346 |
| 45 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.55511148 |
| 46 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.52264391 |
| 47 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.51157151 |
| 48 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.51075199 |
| 49 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.49159229 |
| 50 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.46050837 |
| 51 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.41236622 |
| 52 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.36294734 |
| 53 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.33908104 |
| 54 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.32780791 |
| 55 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.28143012 |
| 56 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.27378433 |
| 57 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.26968663 |
| 58 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.26396154 |
| 59 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.25062087 |
| 60 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.21369393 |
| 61 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.21158442 |
| 62 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.17979519 |
| 63 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.16516280 |
| 64 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.16027404 |
| 65 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.11828042 |
| 66 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.10825327 |
| 67 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.10426966 |
| 68 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.07872162 |
| 69 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.04061553 |
| 70 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.03612120 |
| 71 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.02654982 |
| 72 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.01724459 |
| 73 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.01471055 |
| 74 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.01085591 |
| 75 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.98382711 |
| 76 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.96986384 |
| 77 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.96425220 |
| 78 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.91980949 |
| 79 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 0.88695349 |
| 80 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.88591273 |
| 81 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.88443240 |
| 82 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.84727611 |
| 83 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.83407586 |
| 84 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.80673500 |
| 85 | VDR_22108803_ChIP-Seq_LS180_Human | 0.80587336 |
| 86 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.80352202 |
| 87 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.79782070 |
| 88 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.76454155 |
| 89 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.76409864 |
| 90 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.75861497 |
| 91 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.74866888 |
| 92 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.74581734 |
| 93 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.74375784 |
| 94 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.73329368 |
| 95 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.72168334 |
| 96 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.70386639 |
| 97 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.70200276 |
| 98 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.69602697 |
| 99 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.67992009 |
| 100 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.67609170 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 5.39056502 |
| 2 | MP0003693_abnormal_embryo_hatching | 4.05413163 |
| 3 | MP0004957_abnormal_blastocyst_morpholog | 3.76563572 |
| 4 | MP0008058_abnormal_DNA_repair | 3.64619410 |
| 5 | MP0006292_abnormal_olfactory_placode | 3.46165327 |
| 6 | MP0010094_abnormal_chromosome_stability | 3.14152172 |
| 7 | MP0003718_maternal_effect | 2.79681429 |
| 8 | MP0003806_abnormal_nucleotide_metabolis | 2.73779755 |
| 9 | MP0003186_abnormal_redox_activity | 2.73493846 |
| 10 | MP0003111_abnormal_nucleus_morphology | 2.68288538 |
| 11 | MP0003077_abnormal_cell_cycle | 2.44452692 |
| 12 | MP0008932_abnormal_embryonic_tissue | 2.39081531 |
| 13 | MP0006036_abnormal_mitochondrial_physio | 2.21136775 |
| 14 | MP0008789_abnormal_olfactory_epithelium | 2.20838653 |
| 15 | MP0006035_abnormal_mitochondrial_morpho | 2.17482085 |
| 16 | MP0003786_premature_aging | 2.17285745 |
| 17 | MP0000372_irregular_coat_pigmentation | 2.11288342 |
| 18 | MP0001529_abnormal_vocalization | 2.05264783 |
| 19 | MP0003136_yellow_coat_color | 2.03800541 |
| 20 | MP0001293_anophthalmia | 1.97503302 |
| 21 | MP0008007_abnormal_cellular_replicative | 1.91753923 |
| 22 | MP0003011_delayed_dark_adaptation | 1.78219976 |
| 23 | MP0002938_white_spotting | 1.77856403 |
| 24 | MP0002277_abnormal_respiratory_mucosa | 1.75780718 |
| 25 | MP0008877_abnormal_DNA_methylation | 1.72907593 |
| 26 | MP0003941_abnormal_skin_development | 1.71391577 |
| 27 | MP0010030_abnormal_orbit_morphology | 1.69944007 |
| 28 | MP0005499_abnormal_olfactory_system | 1.58106470 |
| 29 | MP0005394_taste/olfaction_phenotype | 1.58106470 |
| 30 | MP0006072_abnormal_retinal_apoptosis | 1.55471533 |
| 31 | MP0002163_abnormal_gland_morphology | 1.54477909 |
| 32 | MP0005084_abnormal_gallbladder_morpholo | 1.53832235 |
| 33 | MP0002736_abnormal_nociception_after | 1.53358593 |
| 34 | MP0005408_hypopigmentation | 1.51723039 |
| 35 | MP0003123_paternal_imprinting | 1.51664585 |
| 36 | MP0001905_abnormal_dopamine_level | 1.30012426 |
| 37 | MP0008995_early_reproductive_senescence | 1.27280931 |
| 38 | MP0003315_abnormal_perineum_morphology | 1.25773593 |
| 39 | MP0002837_dystrophic_cardiac_calcinosis | 1.19110837 |
| 40 | MP0009697_abnormal_copulation | 1.18747721 |
| 41 | MP0002210_abnormal_sex_determination | 1.18675880 |
| 42 | MP0005075_abnormal_melanosome_morpholog | 1.18271613 |
| 43 | MP0001485_abnormal_pinna_reflex | 1.18259255 |
| 44 | MP0002653_abnormal_ependyma_morphology | 1.17518757 |
| 45 | MP0004147_increased_porphyrin_level | 1.16557986 |
| 46 | MP0004142_abnormal_muscle_tone | 1.15607973 |
| 47 | MP0002132_abnormal_respiratory_system | 1.14947275 |
| 48 | MP0008057_abnormal_DNA_replication | 1.14303453 |
| 49 | MP0003567_abnormal_fetal_cardiomyocyte | 1.12924131 |
| 50 | MP0000358_abnormal_cell_content/ | 1.10814406 |
| 51 | MP0004133_heterotaxia | 1.09366241 |
| 52 | MP0005377_hearing/vestibular/ear_phenot | 1.04388405 |
| 53 | MP0003878_abnormal_ear_physiology | 1.04388405 |
| 54 | MP0009333_abnormal_splenocyte_physiolog | 1.03376347 |
| 55 | MP0002102_abnormal_ear_morphology | 1.03348789 |
| 56 | MP0005379_endocrine/exocrine_gland_phen | 1.02343189 |
| 57 | MP0003121_genomic_imprinting | 1.02246532 |
| 58 | MP0000350_abnormal_cell_proliferation | 1.02243060 |
| 59 | MP0001919_abnormal_reproductive_system | 1.02177970 |
| 60 | MP0008872_abnormal_physiological_respon | 1.02149787 |
| 61 | MP0002095_abnormal_skin_pigmentation | 1.01797102 |
| 62 | MP0005174_abnormal_tail_pigmentation | 1.00001142 |
| 63 | MP0000313_abnormal_cell_death | 0.98934438 |
| 64 | MP0003938_abnormal_ear_development | 0.96527284 |
| 65 | MP0001929_abnormal_gametogenesis | 0.95302049 |
| 66 | MP0001188_hyperpigmentation | 0.92814867 |
| 67 | MP0002751_abnormal_autonomic_nervous | 0.91298288 |
| 68 | MP0005389_reproductive_system_phenotype | 0.90402481 |
| 69 | MP0001145_abnormal_male_reproductive | 0.90249979 |
| 70 | MP0001697_abnormal_embryo_size | 0.88945642 |
| 71 | MP0001730_embryonic_growth_arrest | 0.88044304 |
| 72 | MP0000653_abnormal_sex_gland | 0.87410999 |
| 73 | MP0000490_abnormal_crypts_of | 0.87268394 |
| 74 | MP0000049_abnormal_middle_ear | 0.86950314 |
| 75 | MP0002160_abnormal_reproductive_system | 0.86154876 |
| 76 | MP0001764_abnormal_homeostasis | 0.84211303 |
| 77 | MP0001968_abnormal_touch/_nociception | 0.81526255 |
| 78 | MP0003890_abnormal_embryonic-extraembry | 0.81307960 |
| 79 | MP0002638_abnormal_pupillary_reflex | 0.81165100 |
| 80 | MP0001881_abnormal_mammary_gland | 0.80905245 |
| 81 | MP0003119_abnormal_digestive_system | 0.80548096 |
| 82 | MP0005551_abnormal_eye_electrophysiolog | 0.79658454 |
| 83 | MP0001984_abnormal_olfaction | 0.79336607 |
| 84 | MP0001727_abnormal_embryo_implantation | 0.78608451 |
| 85 | MP0002085_abnormal_embryonic_tissue | 0.77570600 |
| 86 | MP0001286_abnormal_eye_development | 0.75607828 |
| 87 | MP0001119_abnormal_female_reproductive | 0.74818511 |
| 88 | MP0003937_abnormal_limbs/digits/tail_de | 0.73860131 |
| 89 | MP0000631_abnormal_neuroendocrine_gland | 0.73572771 |
| 90 | MP0002254_reproductive_system_inflammat | 0.72468625 |
| 91 | MP0005671_abnormal_response_to | 0.72006411 |
| 92 | MP0002080_prenatal_lethality | 0.71747228 |
| 93 | MP0008875_abnormal_xenobiotic_pharmacok | 0.70940198 |
| 94 | MP0002019_abnormal_tumor_incidence | 0.68060570 |
| 95 | MP0005253_abnormal_eye_physiology | 0.66955475 |
| 96 | MP0002233_abnormal_nose_morphology | 0.66564900 |
| 97 | MP0005636_abnormal_mineral_homeostasis | 0.66318312 |
| 98 | MP0005645_abnormal_hypothalamus_physiol | 0.63757634 |
| 99 | MP0002111_abnormal_tail_morphology | 0.63307791 |
| 100 | MP0000647_abnormal_sebaceous_gland | 0.63186387 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 6.17466072 |
| 2 | Abnormal mitochondria in muscle tissue (HP:0008316) | 5.60175529 |
| 3 | Mitochondrial inheritance (HP:0001427) | 5.49761651 |
| 4 | Increased hepatocellular lipid droplets (HP:0006565) | 5.42663615 |
| 5 | Acute encephalopathy (HP:0006846) | 5.40721300 |
| 6 | Progressive macrocephaly (HP:0004481) | 5.00748741 |
| 7 | Lipid accumulation in hepatocytes (HP:0006561) | 4.99465212 |
| 8 | Increased CSF lactate (HP:0002490) | 4.95914421 |
| 9 | Hepatocellular necrosis (HP:0001404) | 4.67239298 |
| 10 | Renal Fanconi syndrome (HP:0001994) | 4.36335515 |
| 11 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.28161543 |
| 12 | Reticulocytopenia (HP:0001896) | 4.23880294 |
| 13 | Abnormal number of erythroid precursors (HP:0012131) | 4.20995072 |
| 14 | Hepatic necrosis (HP:0002605) | 4.14896110 |
| 15 | Cerebral edema (HP:0002181) | 3.98634349 |
| 16 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.91348720 |
| 17 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.91348720 |
| 18 | Macrocytic anemia (HP:0001972) | 3.86030817 |
| 19 | Increased intramyocellular lipid droplets (HP:0012240) | 3.72799129 |
| 20 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.63505798 |
| 21 | Aplastic anemia (HP:0001915) | 3.46339904 |
| 22 | Exertional dyspnea (HP:0002875) | 3.40563187 |
| 23 | 3-Methylglutaconic aciduria (HP:0003535) | 3.30867786 |
| 24 | Increased serum lactate (HP:0002151) | 3.28563746 |
| 25 | Lactic acidosis (HP:0003128) | 3.24224171 |
| 26 | Increased muscle lipid content (HP:0009058) | 3.14556970 |
| 27 | Respiratory failure (HP:0002878) | 3.11284917 |
| 28 | Respiratory difficulties (HP:0002880) | 3.10321764 |
| 29 | Exercise intolerance (HP:0003546) | 3.00633648 |
| 30 | Oral leukoplakia (HP:0002745) | 2.99626414 |
| 31 | Colon cancer (HP:0003003) | 2.92466539 |
| 32 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.89815353 |
| 33 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.89056778 |
| 34 | Leukodystrophy (HP:0002415) | 2.88260154 |
| 35 | Optic disc pallor (HP:0000543) | 2.78933885 |
| 36 | Pallor (HP:0000980) | 2.73314181 |
| 37 | Abnormality of renal resorption (HP:0011038) | 2.61813442 |
| 38 | Lethargy (HP:0001254) | 2.58868866 |
| 39 | Type I transferrin isoform profile (HP:0003642) | 2.57361847 |
| 40 | Septo-optic dysplasia (HP:0100842) | 2.55054405 |
| 41 | Microvesicular hepatic steatosis (HP:0001414) | 2.42442958 |
| 42 | Pancytopenia (HP:0001876) | 2.35294282 |
| 43 | Absent thumb (HP:0009777) | 2.31393838 |
| 44 | Methylmalonic aciduria (HP:0012120) | 2.31196254 |
| 45 | Hyperphosphaturia (HP:0003109) | 2.23298269 |
| 46 | Congenital, generalized hypertrichosis (HP:0004540) | 2.20600955 |
| 47 | Methylmalonic acidemia (HP:0002912) | 2.20599397 |
| 48 | Sparse eyelashes (HP:0000653) | 2.19621320 |
| 49 | Abnormality of the labia minora (HP:0012880) | 2.19025879 |
| 50 | Glycosuria (HP:0003076) | 2.18713595 |
| 51 | Abnormality of urine glucose concentration (HP:0011016) | 2.18713595 |
| 52 | Meckel diverticulum (HP:0002245) | 2.15058978 |
| 53 | Rough bone trabeculation (HP:0100670) | 2.11965535 |
| 54 | Hyperglycinemia (HP:0002154) | 2.11341143 |
| 55 | Increased serum pyruvate (HP:0003542) | 2.07914516 |
| 56 | CNS demyelination (HP:0007305) | 2.05999926 |
| 57 | Multiple enchondromatosis (HP:0005701) | 2.03211046 |
| 58 | Reduced antithrombin III activity (HP:0001976) | 2.02208428 |
| 59 | Abnormality of the anterior horn cell (HP:0006802) | 2.02154150 |
| 60 | Degeneration of anterior horn cells (HP:0002398) | 2.02154150 |
| 61 | Cellular immunodeficiency (HP:0005374) | 2.00436629 |
| 62 | X-linked dominant inheritance (HP:0001423) | 1.99823904 |
| 63 | Abnormality of the ileum (HP:0001549) | 1.99823317 |
| 64 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.99010891 |
| 65 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.99010891 |
| 66 | Abnormal protein glycosylation (HP:0012346) | 1.99010891 |
| 67 | Abnormal glycosylation (HP:0012345) | 1.99010891 |
| 68 | Absent septum pellucidum (HP:0001331) | 1.97911821 |
| 69 | Hypoplasia of the pons (HP:0012110) | 1.95564366 |
| 70 | Abnormality of methionine metabolism (HP:0010901) | 1.93346781 |
| 71 | Abnormality of placental membranes (HP:0011409) | 1.91781631 |
| 72 | Amniotic constriction ring (HP:0009775) | 1.91781631 |
| 73 | Abnormality of the pons (HP:0007361) | 1.90766437 |
| 74 | Horseshoe kidney (HP:0000085) | 1.89673037 |
| 75 | Abnormality of serum amino acid levels (HP:0003112) | 1.89297890 |
| 76 | Pancreatic cysts (HP:0001737) | 1.88214526 |
| 77 | Generalized aminoaciduria (HP:0002909) | 1.86429881 |
| 78 | Pancreatic fibrosis (HP:0100732) | 1.86322281 |
| 79 | Abnormality of the preputium (HP:0100587) | 1.85785944 |
| 80 | Cerebral hypomyelination (HP:0006808) | 1.84317678 |
| 81 | Megaloblastic anemia (HP:0001889) | 1.83732839 |
| 82 | Abnormality of glycolysis (HP:0004366) | 1.82513779 |
| 83 | Cleft eyelid (HP:0000625) | 1.80662364 |
| 84 | Sclerocornea (HP:0000647) | 1.76036801 |
| 85 | Emotional lability (HP:0000712) | 1.75610656 |
| 86 | Abnormality of the septum pellucidum (HP:0007375) | 1.75377084 |
| 87 | Blindness (HP:0000618) | 1.73775270 |
| 88 | Molar tooth sign on MRI (HP:0002419) | 1.73347759 |
| 89 | Abnormality of midbrain morphology (HP:0002418) | 1.73347759 |
| 90 | Testicular atrophy (HP:0000029) | 1.72974365 |
| 91 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.72839438 |
| 92 | Abnormal lung lobation (HP:0002101) | 1.72411698 |
| 93 | Triphalangeal thumb (HP:0001199) | 1.70730684 |
| 94 | Birth length less than 3rd percentile (HP:0003561) | 1.70533204 |
| 95 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.70287843 |
| 96 | True hermaphroditism (HP:0010459) | 1.68495417 |
| 97 | Abnormal urine phosphate concentration (HP:0012599) | 1.66621145 |
| 98 | Pendular nystagmus (HP:0012043) | 1.65070610 |
| 99 | Abnormal trabecular bone morphology (HP:0100671) | 1.64015514 |
| 100 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 1.63901333 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 6.10327480 |
| 2 | BUB1 | 4.45592057 |
| 3 | NME2 | 3.20548093 |
| 4 | STK16 | 3.12235664 |
| 5 | CDC7 | 2.90696724 |
| 6 | PBK | 2.76928603 |
| 7 | MST4 | 2.76089480 |
| 8 | SRPK1 | 2.71155437 |
| 9 | NME1 | 2.68735837 |
| 10 | VRK1 | 2.58331073 |
| 11 | TESK2 | 2.22747590 |
| 12 | EIF2AK1 | 2.20853356 |
| 13 | ZAK | 2.19203540 |
| 14 | NEK1 | 2.12001292 |
| 15 | MAP3K12 | 2.09987442 |
| 16 | TSSK6 | 1.95986829 |
| 17 | PLK3 | 1.79481966 |
| 18 | TTK | 1.71085504 |
| 19 | KDR | 1.67979025 |
| 20 | NUAK1 | 1.67603918 |
| 21 | DYRK2 | 1.58331233 |
| 22 | WEE1 | 1.53457917 |
| 23 | PLK4 | 1.51403289 |
| 24 | BCKDK | 1.45831398 |
| 25 | EIF2AK3 | 1.38932779 |
| 26 | PLK1 | 1.34230791 |
| 27 | LIMK1 | 1.31410538 |
| 28 | TAF1 | 1.29718394 |
| 29 | WNK3 | 1.28099770 |
| 30 | TESK1 | 1.27754697 |
| 31 | TRIM28 | 1.21463221 |
| 32 | TLK1 | 1.15163342 |
| 33 | BRSK2 | 1.10180676 |
| 34 | AURKB | 1.04720814 |
| 35 | CHEK2 | 1.00116682 |
| 36 | TNIK | 0.99593382 |
| 37 | MKNK1 | 0.98523496 |
| 38 | MKNK2 | 0.97575017 |
| 39 | DYRK3 | 0.96357389 |
| 40 | PAK4 | 0.92613262 |
| 41 | ILK | 0.92062358 |
| 42 | BRSK1 | 0.89770614 |
| 43 | WNK4 | 0.87115731 |
| 44 | PDK2 | 0.86185564 |
| 45 | PASK | 0.84819415 |
| 46 | ATR | 0.84522006 |
| 47 | CSNK2A2 | 0.83990509 |
| 48 | AURKA | 0.83920773 |
| 49 | CSNK2A1 | 0.77279734 |
| 50 | LRRK2 | 0.76055161 |
| 51 | PRKCI | 0.73974580 |
| 52 | ADRBK2 | 0.72788048 |
| 53 | DAPK1 | 0.71548791 |
| 54 | BMPR1B | 0.66837701 |
| 55 | CDK19 | 0.66560336 |
| 56 | STK4 | 0.66444022 |
| 57 | RPS6KA5 | 0.66122588 |
| 58 | NEK2 | 0.65216636 |
| 59 | PIM2 | 0.63701979 |
| 60 | GRK1 | 0.60847918 |
| 61 | ABL2 | 0.60472278 |
| 62 | EIF2AK2 | 0.58226901 |
| 63 | CDK7 | 0.58224216 |
| 64 | STK39 | 0.53069848 |
| 65 | CSNK1G3 | 0.52251941 |
| 66 | CDK8 | 0.51470637 |
| 67 | RPS6KA4 | 0.50866928 |
| 68 | ARAF | 0.50722684 |
| 69 | MAP4K2 | 0.49551791 |
| 70 | DAPK3 | 0.49158997 |
| 71 | TXK | 0.49096333 |
| 72 | PAK1 | 0.48793400 |
| 73 | ALK | 0.47618043 |
| 74 | CHEK1 | 0.47176412 |
| 75 | PRKCG | 0.47016525 |
| 76 | OXSR1 | 0.45855944 |
| 77 | MAP2K7 | 0.45837466 |
| 78 | CSNK1G1 | 0.44420156 |
| 79 | MYLK | 0.43537766 |
| 80 | ATM | 0.41710601 |
| 81 | INSRR | 0.41227552 |
| 82 | CSNK1E | 0.40755788 |
| 83 | MUSK | 0.40728946 |
| 84 | CSNK1G2 | 0.38511081 |
| 85 | BCR | 0.38146206 |
| 86 | RPS6KB2 | 0.37309858 |
| 87 | ERBB4 | 0.37044097 |
| 88 | CSNK1A1 | 0.36191448 |
| 89 | FGFR1 | 0.32582302 |
| 90 | MAP3K8 | 0.32013488 |
| 91 | MAP3K11 | 0.31243753 |
| 92 | MARK3 | 0.29176556 |
| 93 | CCNB1 | 0.28872900 |
| 94 | CLK1 | 0.28001280 |
| 95 | CSNK1A1L | 0.25416628 |
| 96 | PIM1 | 0.23817703 |
| 97 | CDK1 | 0.23475732 |
| 98 | MINK1 | 0.22796037 |
| 99 | CDK2 | 0.22120002 |
| 100 | CASK | 0.20760925 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.03527955 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 4.99328069 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.42321590 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.85491213 |
| 5 | RNA polymerase_Homo sapiens_hsa03020 | 3.30668909 |
| 6 | DNA replication_Homo sapiens_hsa03030 | 2.97906282 |
| 7 | Protein export_Homo sapiens_hsa03060 | 2.82778738 |
| 8 | Huntingtons disease_Homo sapiens_hsa05016 | 2.81514122 |
| 9 | Mismatch repair_Homo sapiens_hsa03430 | 2.74462979 |
| 10 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.62081108 |
| 11 | Alzheimers disease_Homo sapiens_hsa05010 | 2.50063164 |
| 12 | Homologous recombination_Homo sapiens_hsa03440 | 2.34109190 |
| 13 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.29718019 |
| 14 | Spliceosome_Homo sapiens_hsa03040 | 2.21395431 |
| 15 | Base excision repair_Homo sapiens_hsa03410 | 2.01850333 |
| 16 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.92109856 |
| 17 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.81126105 |
| 18 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.73934309 |
| 19 | RNA transport_Homo sapiens_hsa03013 | 1.69428277 |
| 20 | RNA degradation_Homo sapiens_hsa03018 | 1.57966250 |
| 21 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.56897550 |
| 22 | Basal transcription factors_Homo sapiens_hsa03022 | 1.54298686 |
| 23 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.51021428 |
| 24 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.39275627 |
| 25 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.38352892 |
| 26 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.38075232 |
| 27 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.30233020 |
| 28 | Purine metabolism_Homo sapiens_hsa00230 | 1.21278761 |
| 29 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.19535006 |
| 30 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.17147760 |
| 31 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.13445533 |
| 32 | Sulfur relay system_Homo sapiens_hsa04122 | 1.13130349 |
| 33 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.12204874 |
| 34 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.09568156 |
| 35 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.06361052 |
| 36 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.05615392 |
| 37 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.03864960 |
| 38 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.99008827 |
| 39 | Cell cycle_Homo sapiens_hsa04110 | 0.97434540 |
| 40 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.95229177 |
| 41 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.88741174 |
| 42 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.86901920 |
| 43 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.83412456 |
| 44 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.81160419 |
| 45 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.80967810 |
| 46 | Metabolic pathways_Homo sapiens_hsa01100 | 0.76892774 |
| 47 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.70774944 |
| 48 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.67829911 |
| 49 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.67072206 |
| 50 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.66794989 |
| 51 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.65232276 |
| 52 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.62584855 |
| 53 | Carbon metabolism_Homo sapiens_hsa01200 | 0.62303947 |
| 54 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.59879783 |
| 55 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.56662972 |
| 56 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.55991825 |
| 57 | Peroxisome_Homo sapiens_hsa04146 | 0.55907900 |
| 58 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.53629122 |
| 59 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.45454332 |
| 60 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.45137385 |
| 61 | Phototransduction_Homo sapiens_hsa04744 | 0.41886847 |
| 62 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.41406854 |
| 63 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.39934354 |
| 64 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.38886120 |
| 65 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.38580543 |
| 66 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.37313033 |
| 67 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.36699666 |
| 68 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.32886715 |
| 69 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.32478242 |
| 70 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.31414390 |
| 71 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.30778829 |
| 72 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.29183446 |
| 73 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.27816484 |
| 74 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.27148324 |
| 75 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.24841890 |
| 76 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.24028655 |
| 77 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.23358396 |
| 78 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.22438966 |
| 79 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.21906300 |
| 80 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.21218629 |
| 81 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.21079264 |
| 82 | Retinol metabolism_Homo sapiens_hsa00830 | 0.20433440 |
| 83 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.18299263 |
| 84 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.17505414 |
| 85 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.16666450 |
| 86 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.16269196 |
| 87 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.15497971 |
| 88 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.13597388 |
| 89 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.11787355 |
| 90 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.11664479 |
| 91 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.10810659 |
| 92 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.10702360 |
| 93 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.10412823 |
| 94 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.09797013 |
| 95 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.09773461 |
| 96 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.09343839 |
| 97 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.09216390 |
| 98 | Mineral absorption_Homo sapiens_hsa04978 | 0.08586042 |
| 99 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.08250047 |
| 100 | Asthma_Homo sapiens_hsa05310 | 0.07586371 |

