

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | axonemal dynein complex assembly (GO:0070286) | 7.72305700 |
| 2 | cilium movement (GO:0003341) | 5.80378547 |
| 3 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.74070336 |
| 4 | epithelial cilium movement (GO:0003351) | 5.65431730 |
| 5 | cilium or flagellum-dependent cell motility (GO:0001539) | 5.50731749 |
| 6 | proteasome assembly (GO:0043248) | 5.24172896 |
| 7 | motile cilium assembly (GO:0044458) | 5.04020701 |
| 8 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 4.97719390 |
| 9 | ATP synthesis coupled proton transport (GO:0015986) | 4.91937927 |
| 10 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.91937927 |
| 11 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.75548981 |
| 12 | protein neddylation (GO:0045116) | 4.50666005 |
| 13 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.45424982 |
| 14 | CENP-A containing nucleosome assembly (GO:0034080) | 4.23236643 |
| 15 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.18729286 |
| 16 | respiratory electron transport chain (GO:0022904) | 4.13554229 |
| 17 | chromatin remodeling at centromere (GO:0031055) | 4.11034260 |
| 18 | electron transport chain (GO:0022900) | 4.08457460 |
| 19 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.93632638 |
| 20 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.93065535 |
| 21 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.80112856 |
| 22 | intraciliary transport (GO:0042073) | 3.78296697 |
| 23 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.77411163 |
| 24 | negative regulation of ligase activity (GO:0051352) | 3.77411163 |
| 25 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.74828296 |
| 26 | regulation of cilium movement (GO:0003352) | 3.68372541 |
| 27 | protein complex biogenesis (GO:0070271) | 3.56344494 |
| 28 | axoneme assembly (GO:0035082) | 3.54149034 |
| 29 | establishment of integrated proviral latency (GO:0075713) | 3.52424736 |
| 30 | chaperone-mediated protein transport (GO:0072321) | 3.51336396 |
| 31 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.48009403 |
| 32 | cullin deneddylation (GO:0010388) | 3.47374671 |
| 33 | pseudouridine synthesis (GO:0001522) | 3.43811385 |
| 34 | regulation of mitochondrial translation (GO:0070129) | 3.41806096 |
| 35 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.41774912 |
| 36 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.40057301 |
| 37 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.40057301 |
| 38 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.39316933 |
| 39 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.39316933 |
| 40 | NADH dehydrogenase complex assembly (GO:0010257) | 3.39316933 |
| 41 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.38935041 |
| 42 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.38935041 |
| 43 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.38935041 |
| 44 | histone exchange (GO:0043486) | 3.35557932 |
| 45 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.34625293 |
| 46 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.30775016 |
| 47 | centriole replication (GO:0007099) | 3.30498861 |
| 48 | centriole assembly (GO:0098534) | 3.28238346 |
| 49 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.27672607 |
| 50 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.27672607 |
| 51 | DNA double-strand break processing (GO:0000729) | 3.26547819 |
| 52 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.23697141 |
| 53 | positive regulation of ligase activity (GO:0051351) | 3.23299039 |
| 54 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.22929305 |
| 55 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.22929305 |
| 56 | nucleoside diphosphate phosphorylation (GO:0006165) | 3.19683483 |
| 57 | GTP biosynthetic process (GO:0006183) | 3.18113632 |
| 58 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.17081635 |
| 59 | protein deneddylation (GO:0000338) | 3.17034235 |
| 60 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.12188884 |
| 61 | protein targeting to mitochondrion (GO:0006626) | 3.12108495 |
| 62 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.09243550 |
| 63 | DNA replication-independent nucleosome organization (GO:0034724) | 3.09243550 |
| 64 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.08934162 |
| 65 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.08449706 |
| 66 | left/right pattern formation (GO:0060972) | 3.07335539 |
| 67 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.03692167 |
| 68 | DNA strand elongation (GO:0022616) | 3.01925647 |
| 69 | respiratory chain complex IV assembly (GO:0008535) | 3.01171098 |
| 70 | protein localization to mitochondrion (GO:0070585) | 2.99950987 |
| 71 | oxidative phosphorylation (GO:0006119) | 2.99612089 |
| 72 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.99153431 |
| 73 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.97741348 |
| 74 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.96375796 |
| 75 | mitotic metaphase plate congression (GO:0007080) | 2.96348371 |
| 76 | metaphase plate congression (GO:0051310) | 2.96328178 |
| 77 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 2.96226087 |
| 78 | establishment of viral latency (GO:0019043) | 2.95679170 |
| 79 | nucleoside triphosphate biosynthetic process (GO:0009142) | 2.94004930 |
| 80 | ATP biosynthetic process (GO:0006754) | 2.93166000 |
| 81 | organelle disassembly (GO:1903008) | 2.92324951 |
| 82 | telomere maintenance via recombination (GO:0000722) | 2.92200337 |
| 83 | DNA deamination (GO:0045006) | 2.91354783 |
| 84 | histone H2A acetylation (GO:0043968) | 2.91233266 |
| 85 | establishment of protein localization to mitochondrion (GO:0072655) | 2.90116999 |
| 86 | regulation of ligase activity (GO:0051340) | 2.89832288 |
| 87 | deoxyribonucleotide biosynthetic process (GO:0009263) | 2.89696438 |
| 88 | DNA replication checkpoint (GO:0000076) | 2.89633661 |
| 89 | spliceosomal snRNP assembly (GO:0000387) | 2.89256708 |
| 90 | purine nucleobase biosynthetic process (GO:0009113) | 2.88619574 |
| 91 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.88504980 |
| 92 | regulation of cellular amine metabolic process (GO:0033238) | 2.87030643 |
| 93 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.86910169 |
| 94 | termination of RNA polymerase III transcription (GO:0006386) | 2.86910169 |
| 95 | rRNA modification (GO:0000154) | 2.86466415 |
| 96 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.85801095 |
| 97 | cilium organization (GO:0044782) | 2.84889956 |
| 98 | protein K6-linked ubiquitination (GO:0085020) | 2.84652988 |
| 99 | mitotic recombination (GO:0006312) | 2.84272712 |
| 100 | cytochrome complex assembly (GO:0017004) | 2.82179852 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.10478741 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.53360076 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.89240332 |
| 4 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.87963857 |
| 5 | E2F7_22180533_ChIP-Seq_HELA_Human | 3.76822835 |
| 6 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.32834012 |
| 7 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.27799892 |
| 8 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.07813456 |
| 9 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.98053656 |
| 10 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.95902921 |
| 11 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.95218012 |
| 12 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.92903771 |
| 13 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.91140545 |
| 14 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.77935498 |
| 15 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.75389521 |
| 16 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.61120854 |
| 17 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.46338213 |
| 18 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.45773397 |
| 19 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.33163073 |
| 20 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.32880120 |
| 21 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.29971528 |
| 22 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.29511476 |
| 23 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.27262178 |
| 24 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.26890426 |
| 25 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.26324469 |
| 26 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.24214557 |
| 27 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.22258064 |
| 28 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 2.07147506 |
| 29 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 2.05648169 |
| 30 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 2.02605562 |
| 31 | VDR_22108803_ChIP-Seq_LS180_Human | 1.98515309 |
| 32 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.96490457 |
| 33 | * GABP_19822575_ChIP-Seq_HepG2_Human | 1.90448978 |
| 34 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.88595091 |
| 35 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.86780810 |
| 36 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.84791342 |
| 37 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.84305050 |
| 38 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.83355114 |
| 39 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.82141786 |
| 40 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.77526254 |
| 41 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.69758336 |
| 42 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.67994967 |
| 43 | EWS_26573619_Chip-Seq_HEK293_Human | 1.63863300 |
| 44 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.62971844 |
| 45 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.60810568 |
| 46 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.58723333 |
| 47 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.57185451 |
| 48 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.55724705 |
| 49 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.48744866 |
| 50 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.46271340 |
| 51 | * E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.44796542 |
| 52 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.41935889 |
| 53 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.38991672 |
| 54 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.38917531 |
| 55 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.38007160 |
| 56 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.28812111 |
| 57 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.25747378 |
| 58 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.20622379 |
| 59 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.19366961 |
| 60 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.19102081 |
| 61 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.18630259 |
| 62 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.16345127 |
| 63 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.10918471 |
| 64 | * E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.10576610 |
| 65 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.09841109 |
| 66 | FUS_26573619_Chip-Seq_HEK293_Human | 1.08828785 |
| 67 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.07219487 |
| 68 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.06661432 |
| 69 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.05572671 |
| 70 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.05197712 |
| 71 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.05112820 |
| 72 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.04136815 |
| 73 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.04061575 |
| 74 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.00843056 |
| 75 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.96336420 |
| 76 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.94961509 |
| 77 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.92360952 |
| 78 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.92245237 |
| 79 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.89514958 |
| 80 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.88975858 |
| 81 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 0.88821206 |
| 82 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.88766865 |
| 83 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.88745141 |
| 84 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 0.87453279 |
| 85 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.86687517 |
| 86 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.83438650 |
| 87 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.82008517 |
| 88 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.81784582 |
| 89 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.80235348 |
| 90 | AR_20517297_ChIP-Seq_VCAP_Human | 0.79013926 |
| 91 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 0.78812105 |
| 92 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 0.78457302 |
| 93 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.75247542 |
| 94 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.75002978 |
| 95 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.73316327 |
| 96 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.72951884 |
| 97 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.72611079 |
| 98 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.72174603 |
| 99 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.72161016 |
| 100 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.71698063 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003806_abnormal_nucleotide_metabolis | 5.03904908 |
| 2 | MP0010094_abnormal_chromosome_stability | 3.71411816 |
| 3 | MP0008058_abnormal_DNA_repair | 3.40949979 |
| 4 | MP0003693_abnormal_embryo_hatching | 3.12206988 |
| 5 | MP0004957_abnormal_blastocyst_morpholog | 3.08743674 |
| 6 | MP0008875_abnormal_xenobiotic_pharmacok | 3.02925188 |
| 7 | MP0002653_abnormal_ependyma_morphology | 2.63564332 |
| 8 | MP0006036_abnormal_mitochondrial_physio | 2.63148528 |
| 9 | MP0003186_abnormal_redox_activity | 2.52918356 |
| 10 | MP0003786_premature_aging | 2.51138605 |
| 11 | MP0003718_maternal_effect | 2.47545010 |
| 12 | MP0003111_abnormal_nucleus_morphology | 2.43098463 |
| 13 | MP0000372_irregular_coat_pigmentation | 2.39527082 |
| 14 | MP0003077_abnormal_cell_cycle | 2.32199234 |
| 15 | MP0002277_abnormal_respiratory_mucosa | 2.18215868 |
| 16 | MP0009697_abnormal_copulation | 2.17864136 |
| 17 | MP0002132_abnormal_respiratory_system | 2.17678457 |
| 18 | MP0008932_abnormal_embryonic_tissue | 2.13474198 |
| 19 | MP0008057_abnormal_DNA_replication | 2.12332590 |
| 20 | MP0008789_abnormal_olfactory_epithelium | 2.11636908 |
| 21 | MP0001529_abnormal_vocalization | 2.11346237 |
| 22 | MP0008007_abnormal_cellular_replicative | 2.10170183 |
| 23 | MP0006035_abnormal_mitochondrial_morpho | 2.06521648 |
| 24 | MP0002837_dystrophic_cardiac_calcinosis | 1.91614923 |
| 25 | MP0001984_abnormal_olfaction | 1.76176570 |
| 26 | MP0005408_hypopigmentation | 1.73555196 |
| 27 | MP0001764_abnormal_homeostasis | 1.70911797 |
| 28 | MP0009379_abnormal_foot_pigmentation | 1.64199569 |
| 29 | MP0006072_abnormal_retinal_apoptosis | 1.60823027 |
| 30 | MP0002160_abnormal_reproductive_system | 1.51462417 |
| 31 | MP0005084_abnormal_gallbladder_morpholo | 1.49172669 |
| 32 | MP0002102_abnormal_ear_morphology | 1.49155927 |
| 33 | MP0000358_abnormal_cell_content/ | 1.42859017 |
| 34 | MP0008995_early_reproductive_senescence | 1.39975879 |
| 35 | MP0004133_heterotaxia | 1.38114733 |
| 36 | MP0003136_yellow_coat_color | 1.32676431 |
| 37 | MP0005645_abnormal_hypothalamus_physiol | 1.28806905 |
| 38 | MP0001929_abnormal_gametogenesis | 1.28075025 |
| 39 | MP0002736_abnormal_nociception_after | 1.25102434 |
| 40 | MP0005395_other_phenotype | 1.23927581 |
| 41 | MP0001293_anophthalmia | 1.22668190 |
| 42 | MP0002139_abnormal_hepatobiliary_system | 1.17219966 |
| 43 | MP0002163_abnormal_gland_morphology | 1.15441694 |
| 44 | MP0004215_abnormal_myocardial_fiber | 1.14680976 |
| 45 | MP0002210_abnormal_sex_determination | 1.13901543 |
| 46 | MP0002938_white_spotting | 1.12798999 |
| 47 | MP0003195_calcinosis | 1.12391486 |
| 48 | MP0005636_abnormal_mineral_homeostasis | 1.12061857 |
| 49 | MP0005499_abnormal_olfactory_system | 1.11151920 |
| 50 | MP0005394_taste/olfaction_phenotype | 1.11151920 |
| 51 | MP0005253_abnormal_eye_physiology | 1.09330445 |
| 52 | MP0004019_abnormal_vitamin_homeostasis | 1.01105533 |
| 53 | MP0005075_abnormal_melanosome_morpholog | 0.97082240 |
| 54 | MP0008873_increased_physiological_sensi | 0.96891135 |
| 55 | MP0002282_abnormal_trachea_morphology | 0.94680956 |
| 56 | MP0005646_abnormal_pituitary_gland | 0.94491363 |
| 57 | MP0000516_abnormal_urinary_system | 0.92710066 |
| 58 | MP0005367_renal/urinary_system_phenotyp | 0.92710066 |
| 59 | MP0000343_altered_response_to | 0.91970439 |
| 60 | MP0000350_abnormal_cell_proliferation | 0.91874214 |
| 61 | MP0000653_abnormal_sex_gland | 0.91464219 |
| 62 | MP0001727_abnormal_embryo_implantation | 0.89907267 |
| 63 | MP0002019_abnormal_tumor_incidence | 0.89223095 |
| 64 | MP0005389_reproductive_system_phenotype | 0.89172501 |
| 65 | MP0000313_abnormal_cell_death | 0.86986442 |
| 66 | MP0002090_abnormal_vision | 0.86812551 |
| 67 | MP0009333_abnormal_splenocyte_physiolog | 0.85187499 |
| 68 | MP0009046_muscle_twitch | 0.84311740 |
| 69 | MP0001145_abnormal_male_reproductive | 0.84258985 |
| 70 | MP0005165_increased_susceptibility_to | 0.83560482 |
| 71 | MP0002638_abnormal_pupillary_reflex | 0.83548754 |
| 72 | MP0008877_abnormal_DNA_methylation | 0.83125007 |
| 73 | MP0003698_abnormal_male_reproductive | 0.82371102 |
| 74 | MP0004043_abnormal_pH_regulation | 0.81189863 |
| 75 | MP0003941_abnormal_skin_development | 0.81135724 |
| 76 | MP0006292_abnormal_olfactory_placode | 0.80179838 |
| 77 | MP0010307_abnormal_tumor_latency | 0.79361839 |
| 78 | MP0005623_abnormal_meninges_morphology | 0.76794222 |
| 79 | MP0005332_abnormal_amino_acid | 0.76457892 |
| 80 | MP0005410_abnormal_fertilization | 0.75881404 |
| 81 | MP0002095_abnormal_skin_pigmentation | 0.75122309 |
| 82 | MP0001119_abnormal_female_reproductive | 0.74787799 |
| 83 | MP0005379_endocrine/exocrine_gland_phen | 0.73436266 |
| 84 | MP0001905_abnormal_dopamine_level | 0.72219618 |
| 85 | MP0000647_abnormal_sebaceous_gland | 0.70676305 |
| 86 | MP0001853_heart_inflammation | 0.69678809 |
| 87 | MP0000490_abnormal_crypts_of | 0.69504099 |
| 88 | MP0008872_abnormal_physiological_respon | 0.69399894 |
| 89 | MP0002909_abnormal_adrenal_gland | 0.68971292 |
| 90 | MP0002148_abnormal_hypersensitivity_rea | 0.66999710 |
| 91 | MP0001730_embryonic_growth_arrest | 0.66926379 |
| 92 | MP0006082_CNS_inflammation | 0.66896073 |
| 93 | MP0010678_abnormal_skin_adnexa | 0.66075536 |
| 94 | MP0001697_abnormal_embryo_size | 0.65999418 |
| 95 | MP0005187_abnormal_penis_morphology | 0.65620339 |
| 96 | MP0003123_paternal_imprinting | 0.65339704 |
| 97 | MP0002080_prenatal_lethality | 0.64905056 |
| 98 | MP0000631_abnormal_neuroendocrine_gland | 0.64314792 |
| 99 | MP0004147_increased_porphyrin_level | 0.63830256 |
| 100 | MP0003890_abnormal_embryonic-extraembry | 0.62795532 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 7.90799436 |
| 2 | Abnormal respiratory motile cilium physiology (HP:0012261) | 6.84666311 |
| 3 | Abnormal ciliary motility (HP:0012262) | 6.50652587 |
| 4 | Abnormal respiratory epithelium morphology (HP:0012253) | 6.48848437 |
| 5 | Abnormal respiratory motile cilium morphology (HP:0005938) | 6.48848437 |
| 6 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 6.39955449 |
| 7 | Absent/shortened dynein arms (HP:0200106) | 6.39955449 |
| 8 | Rhinitis (HP:0012384) | 6.20783926 |
| 9 | Chronic bronchitis (HP:0004469) | 4.92261077 |
| 10 | Bronchiectasis (HP:0002110) | 4.37021139 |
| 11 | Acute necrotizing encephalopathy (HP:0006965) | 4.12398928 |
| 12 | Increased hepatocellular lipid droplets (HP:0006565) | 4.09897087 |
| 13 | Mitochondrial inheritance (HP:0001427) | 3.84599409 |
| 14 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.75933836 |
| 15 | Lipid accumulation in hepatocytes (HP:0006561) | 3.74698849 |
| 16 | Increased CSF lactate (HP:0002490) | 3.62305061 |
| 17 | Acute encephalopathy (HP:0006846) | 3.59216710 |
| 18 | Progressive macrocephaly (HP:0004481) | 3.54907099 |
| 19 | Renal Fanconi syndrome (HP:0001994) | 3.52983351 |
| 20 | True hermaphroditism (HP:0010459) | 3.51378853 |
| 21 | Pancreatic fibrosis (HP:0100732) | 3.50636929 |
| 22 | Nasal polyposis (HP:0100582) | 3.25476567 |
| 23 | Hepatocellular necrosis (HP:0001404) | 3.23450833 |
| 24 | Pancreatic cysts (HP:0001737) | 3.18499433 |
| 25 | Hepatic necrosis (HP:0002605) | 3.14454084 |
| 26 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.88921651 |
| 27 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.88921651 |
| 28 | Cerebral edema (HP:0002181) | 2.85876790 |
| 29 | Abnormality of midbrain morphology (HP:0002418) | 2.79616676 |
| 30 | Molar tooth sign on MRI (HP:0002419) | 2.79616676 |
| 31 | Chronic sinusitis (HP:0011109) | 2.77626033 |
| 32 | Increased intramyocellular lipid droplets (HP:0012240) | 2.69670174 |
| 33 | 3-Methylglutaconic aciduria (HP:0003535) | 2.66510477 |
| 34 | Bronchitis (HP:0012387) | 2.66292481 |
| 35 | Exertional dyspnea (HP:0002875) | 2.65929507 |
| 36 | Occipital encephalocele (HP:0002085) | 2.57900240 |
| 37 | Recurrent sinusitis (HP:0011108) | 2.53024654 |
| 38 | Abnormality of the nasal mucosa (HP:0000433) | 2.51461746 |
| 39 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.46245822 |
| 40 | Nephronophthisis (HP:0000090) | 2.41604389 |
| 41 | Exercise intolerance (HP:0003546) | 2.40295866 |
| 42 | Lactic acidosis (HP:0003128) | 2.39995270 |
| 43 | Respiratory failure (HP:0002878) | 2.39698538 |
| 44 | Increased serum lactate (HP:0002151) | 2.38442180 |
| 45 | Medial flaring of the eyebrow (HP:0010747) | 2.33082180 |
| 46 | Abnormality of renal resorption (HP:0011038) | 2.23394399 |
| 47 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.21471470 |
| 48 | Infertility (HP:0000789) | 2.17691450 |
| 49 | Degeneration of anterior horn cells (HP:0002398) | 2.17371550 |
| 50 | Abnormality of the anterior horn cell (HP:0006802) | 2.17371550 |
| 51 | Increased muscle lipid content (HP:0009058) | 2.16210641 |
| 52 | Postaxial foot polydactyly (HP:0001830) | 2.16105660 |
| 53 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.15582437 |
| 54 | Sclerocornea (HP:0000647) | 2.09692600 |
| 55 | Male pseudohermaphroditism (HP:0000037) | 2.06146966 |
| 56 | Respiratory difficulties (HP:0002880) | 2.03753943 |
| 57 | Increased serum pyruvate (HP:0003542) | 2.01700112 |
| 58 | Cystic liver disease (HP:0006706) | 1.96849936 |
| 59 | Recurrent otitis media (HP:0000403) | 1.96629448 |
| 60 | Chronic hepatic failure (HP:0100626) | 1.95544654 |
| 61 | Congenital primary aphakia (HP:0007707) | 1.93700560 |
| 62 | Methylmalonic acidemia (HP:0002912) | 1.93545345 |
| 63 | Anencephaly (HP:0002323) | 1.92657753 |
| 64 | Congenital hepatic fibrosis (HP:0002612) | 1.91815175 |
| 65 | Lethargy (HP:0001254) | 1.90692269 |
| 66 | Median cleft lip (HP:0000161) | 1.90266130 |
| 67 | Supernumerary spleens (HP:0009799) | 1.85534766 |
| 68 | Optic disc pallor (HP:0000543) | 1.84659179 |
| 69 | Aplastic anemia (HP:0001915) | 1.82880407 |
| 70 | Type I transferrin isoform profile (HP:0003642) | 1.81948952 |
| 71 | Abnormality of methionine metabolism (HP:0010901) | 1.81772389 |
| 72 | CNS demyelination (HP:0007305) | 1.81322972 |
| 73 | Hypoglycemic coma (HP:0001325) | 1.80839801 |
| 74 | Furrowed tongue (HP:0000221) | 1.78629524 |
| 75 | Generalized aminoaciduria (HP:0002909) | 1.78450489 |
| 76 | Abnormal protein glycosylation (HP:0012346) | 1.78179920 |
| 77 | Abnormal glycosylation (HP:0012345) | 1.78179920 |
| 78 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.78179920 |
| 79 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.78179920 |
| 80 | Gait imbalance (HP:0002141) | 1.77897975 |
| 81 | Abnormality of urine glucose concentration (HP:0011016) | 1.77194451 |
| 82 | Glycosuria (HP:0003076) | 1.77194451 |
| 83 | Abnormality of the renal medulla (HP:0100957) | 1.75837570 |
| 84 | Chronic otitis media (HP:0000389) | 1.74615110 |
| 85 | Oculomotor apraxia (HP:0000657) | 1.71400224 |
| 86 | Nephrogenic diabetes insipidus (HP:0009806) | 1.70968037 |
| 87 | Male infertility (HP:0003251) | 1.69444842 |
| 88 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.69323042 |
| 89 | Leukodystrophy (HP:0002415) | 1.69041331 |
| 90 | Abnormality of glycolysis (HP:0004366) | 1.65087075 |
| 91 | Abnormality of alanine metabolism (HP:0010916) | 1.64360072 |
| 92 | Hyperalaninemia (HP:0003348) | 1.64360072 |
| 93 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.64360072 |
| 94 | Congenital, generalized hypertrichosis (HP:0004540) | 1.59855586 |
| 95 | Postaxial hand polydactyly (HP:0001162) | 1.59241533 |
| 96 | Abnormal number of erythroid precursors (HP:0012131) | 1.58498490 |
| 97 | Pancytopenia (HP:0001876) | 1.58039811 |
| 98 | Reduced antithrombin III activity (HP:0001976) | 1.57920875 |
| 99 | Methylmalonic aciduria (HP:0012120) | 1.57592270 |
| 100 | Abnormality of the renal cortex (HP:0011035) | 1.55705456 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MST4 | 4.00911729 |
| 2 | VRK2 | 3.77577819 |
| 3 | BUB1 | 3.48728267 |
| 4 | EIF2AK1 | 2.94796421 |
| 5 | EIF2AK3 | 2.79316076 |
| 6 | PBK | 2.69702692 |
| 7 | NEK1 | 2.68292535 |
| 8 | VRK1 | 2.47367356 |
| 9 | WEE1 | 2.37290413 |
| 10 | SRPK1 | 2.31649254 |
| 11 | MAPK15 | 2.22932976 |
| 12 | NME2 | 2.06619431 |
| 13 | TTK | 2.06545524 |
| 14 | CDC7 | 2.04110093 |
| 15 | PLK4 | 1.96119333 |
| 16 | STK16 | 1.94884180 |
| 17 | TESK1 | 1.92081102 |
| 18 | CCNB1 | 1.90616035 |
| 19 | ZAK | 1.84742186 |
| 20 | TSSK6 | 1.81884066 |
| 21 | BRSK2 | 1.77936081 |
| 22 | PLK3 | 1.74504578 |
| 23 | NUAK1 | 1.72211935 |
| 24 | MAP4K2 | 1.64335365 |
| 25 | MAP3K12 | 1.60657180 |
| 26 | BCR | 1.52099566 |
| 27 | PNCK | 1.51404068 |
| 28 | SCYL2 | 1.44794384 |
| 29 | ERBB3 | 1.43754450 |
| 30 | NME1 | 1.40723644 |
| 31 | TAF1 | 1.39746607 |
| 32 | WNK3 | 1.38682585 |
| 33 | MKNK1 | 1.36561479 |
| 34 | TRIM28 | 1.35899722 |
| 35 | PLK1 | 1.24147485 |
| 36 | BCKDK | 1.16375643 |
| 37 | MKNK2 | 1.12514380 |
| 38 | DYRK3 | 1.11838219 |
| 39 | ACVR1B | 1.10974696 |
| 40 | STK4 | 1.07195371 |
| 41 | RPS6KA4 | 1.05436231 |
| 42 | CSNK1G2 | 1.05233499 |
| 43 | FRK | 1.04462038 |
| 44 | TLK1 | 1.02555916 |
| 45 | CSNK1G3 | 1.02215396 |
| 46 | AURKB | 0.99227768 |
| 47 | BMPR1B | 0.96331680 |
| 48 | MAP2K7 | 0.94920390 |
| 49 | PIM2 | 0.88618318 |
| 50 | PDK2 | 0.86494580 |
| 51 | CSNK1G1 | 0.85601630 |
| 52 | ATR | 0.79325853 |
| 53 | AURKA | 0.75786485 |
| 54 | RPS6KA5 | 0.73528787 |
| 55 | LIMK1 | 0.71521235 |
| 56 | STK24 | 0.70394551 |
| 57 | PLK2 | 0.69735063 |
| 58 | DYRK2 | 0.68662312 |
| 59 | MAP3K4 | 0.67800988 |
| 60 | EPHA2 | 0.67061383 |
| 61 | KDR | 0.66944021 |
| 62 | EIF2AK2 | 0.62557077 |
| 63 | BRSK1 | 0.62092384 |
| 64 | GRK1 | 0.61295616 |
| 65 | CHEK2 | 0.61081005 |
| 66 | CSNK2A1 | 0.58244794 |
| 67 | STK3 | 0.57713774 |
| 68 | DAPK1 | 0.56973067 |
| 69 | CSNK1A1L | 0.56292620 |
| 70 | CSNK2A2 | 0.54887004 |
| 71 | ADRBK2 | 0.54109030 |
| 72 | OXSR1 | 0.51335388 |
| 73 | BMPR2 | 0.51063428 |
| 74 | STK39 | 0.50866133 |
| 75 | STK10 | 0.49962986 |
| 76 | EPHA3 | 0.49515766 |
| 77 | STK38L | 0.47896573 |
| 78 | PRKCI | 0.47305088 |
| 79 | MAP3K8 | 0.45273555 |
| 80 | ERBB4 | 0.45034580 |
| 81 | PAK4 | 0.44300182 |
| 82 | PASK | 0.43726710 |
| 83 | ARAF | 0.42126068 |
| 84 | MAPKAPK3 | 0.41542705 |
| 85 | CLK1 | 0.41434242 |
| 86 | MINK1 | 0.41121720 |
| 87 | ATM | 0.39999924 |
| 88 | ABL2 | 0.39962112 |
| 89 | MYLK | 0.38139938 |
| 90 | ILK | 0.36719548 |
| 91 | CHEK1 | 0.35375537 |
| 92 | TAOK1 | 0.29781170 |
| 93 | LRRK2 | 0.29426351 |
| 94 | TESK2 | 0.28090543 |
| 95 | TEC | 0.27933456 |
| 96 | WNK4 | 0.25559946 |
| 97 | PTK2B | 0.25294203 |
| 98 | CSNK1A1 | 0.23724977 |
| 99 | FER | 0.23052947 |
| 100 | PAK1 | 0.22770807 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.50345024 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.78815760 |
| 3 | Mismatch repair_Homo sapiens_hsa03430 | 3.22576485 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.17523446 |
| 5 | Protein export_Homo sapiens_hsa03060 | 3.01475613 |
| 6 | DNA replication_Homo sapiens_hsa03030 | 2.94244897 |
| 7 | Huntingtons disease_Homo sapiens_hsa05016 | 2.80355408 |
| 8 | Ribosome_Homo sapiens_hsa03010 | 2.62505038 |
| 9 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.28533900 |
| 10 | RNA polymerase_Homo sapiens_hsa03020 | 2.25361069 |
| 11 | Homologous recombination_Homo sapiens_hsa03440 | 2.18013284 |
| 12 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.09246108 |
| 13 | Alzheimers disease_Homo sapiens_hsa05010 | 1.95824300 |
| 14 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.95367502 |
| 15 | Spliceosome_Homo sapiens_hsa03040 | 1.90057310 |
| 16 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.83965794 |
| 17 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.75751097 |
| 18 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.74449560 |
| 19 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.74336956 |
| 20 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.71694154 |
| 21 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.68587971 |
| 22 | RNA transport_Homo sapiens_hsa03013 | 1.62042021 |
| 23 | Base excision repair_Homo sapiens_hsa03410 | 1.61383046 |
| 24 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.53488068 |
| 25 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.44947795 |
| 26 | Basal transcription factors_Homo sapiens_hsa03022 | 1.43425937 |
| 27 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.42650069 |
| 28 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.36305901 |
| 29 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.36145919 |
| 30 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.35733114 |
| 31 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.34841884 |
| 32 | RNA degradation_Homo sapiens_hsa03018 | 1.31906945 |
| 33 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.31042109 |
| 34 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.30191222 |
| 35 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.26710290 |
| 36 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.24315352 |
| 37 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.23849455 |
| 38 | Purine metabolism_Homo sapiens_hsa00230 | 1.22297505 |
| 39 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.15710233 |
| 40 | Peroxisome_Homo sapiens_hsa04146 | 1.11581092 |
| 41 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.05537181 |
| 42 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.04191069 |
| 43 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.02009665 |
| 44 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.01143921 |
| 45 | Cell cycle_Homo sapiens_hsa04110 | 1.00482446 |
| 46 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.95815145 |
| 47 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.93945134 |
| 48 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.90905174 |
| 49 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.89924390 |
| 50 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.89593343 |
| 51 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.88360332 |
| 52 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.87970081 |
| 53 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.87918623 |
| 54 | Metabolic pathways_Homo sapiens_hsa01100 | 0.83753169 |
| 55 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.83120125 |
| 56 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.79902877 |
| 57 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.79218918 |
| 58 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.76696112 |
| 59 | Carbon metabolism_Homo sapiens_hsa01200 | 0.71374149 |
| 60 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.70981189 |
| 61 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.70156417 |
| 62 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.69856761 |
| 63 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.67815967 |
| 64 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.64823928 |
| 65 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.63181270 |
| 66 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.58410043 |
| 67 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.58120873 |
| 68 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.55206441 |
| 69 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.54814060 |
| 70 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.54738310 |
| 71 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.50862202 |
| 72 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.50328082 |
| 73 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.49959078 |
| 74 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.48561366 |
| 75 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.48495504 |
| 76 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.48025876 |
| 77 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.46916203 |
| 78 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.46066658 |
| 79 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.45614898 |
| 80 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.45454376 |
| 81 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.44046114 |
| 82 | Retinol metabolism_Homo sapiens_hsa00830 | 0.44011838 |
| 83 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.43935420 |
| 84 | Histidine metabolism_Homo sapiens_hsa00340 | 0.43657526 |
| 85 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.43569276 |
| 86 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.42385615 |
| 87 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.39221709 |
| 88 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.39001676 |
| 89 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.37803927 |
| 90 | Alcoholism_Homo sapiens_hsa05034 | 0.36712576 |
| 91 | Asthma_Homo sapiens_hsa05310 | 0.34497069 |
| 92 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.32736049 |
| 93 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.30794017 |
| 94 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.30631740 |
| 95 | Sulfur relay system_Homo sapiens_hsa04122 | 0.27955399 |
| 96 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.27917852 |
| 97 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.24625585 |
| 98 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.23678800 |
| 99 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.22927786 |
| 100 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.21035857 |

