

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 8.96280089 |
| 2 | ATP synthesis coupled proton transport (GO:0015986) | 7.84134628 |
| 3 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 7.84134628 |
| 4 | viral transcription (GO:0019083) | 7.13698022 |
| 5 | translational termination (GO:0006415) | 6.92609953 |
| 6 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 6.72609000 |
| 7 | respiratory electron transport chain (GO:0022904) | 6.50936406 |
| 8 | electron transport chain (GO:0022900) | 6.39464947 |
| 9 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 6.21701601 |
| 10 | cotranslational protein targeting to membrane (GO:0006613) | 6.17970350 |
| 11 | ribosomal small subunit assembly (GO:0000028) | 6.13345136 |
| 12 | protein targeting to ER (GO:0045047) | 6.12205667 |
| 13 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.93922646 |
| 14 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 5.88410919 |
| 15 | protein localization to endoplasmic reticulum (GO:0070972) | 5.77185310 |
| 16 | translational elongation (GO:0006414) | 5.75802774 |
| 17 | chaperone-mediated protein transport (GO:0072321) | 5.62434396 |
| 18 | protein complex biogenesis (GO:0070271) | 5.49890952 |
| 19 | ribosomal small subunit biogenesis (GO:0042274) | 5.36885751 |
| 20 | cellular protein complex disassembly (GO:0043624) | 5.33376761 |
| 21 | viral life cycle (GO:0019058) | 5.25649622 |
| 22 | mitochondrial respiratory chain complex assembly (GO:0033108) | 5.13817668 |
| 23 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 5.11164918 |
| 24 | NADH dehydrogenase complex assembly (GO:0010257) | 5.11164918 |
| 25 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 5.11164918 |
| 26 | maturation of SSU-rRNA (GO:0030490) | 5.10501939 |
| 27 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 5.10018622 |
| 28 | translational initiation (GO:0006413) | 4.87956854 |
| 29 | protein neddylation (GO:0045116) | 4.73693104 |
| 30 | ribosomal large subunit biogenesis (GO:0042273) | 4.61106178 |
| 31 | hydrogen ion transmembrane transport (GO:1902600) | 4.47592152 |
| 32 | protein complex disassembly (GO:0043241) | 4.47122686 |
| 33 | ATP biosynthetic process (GO:0006754) | 4.43167878 |
| 34 | macromolecular complex disassembly (GO:0032984) | 4.29504112 |
| 35 | translation (GO:0006412) | 4.24047195 |
| 36 | proteasome assembly (GO:0043248) | 4.13385585 |
| 37 | protein targeting to membrane (GO:0006612) | 4.07509558 |
| 38 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 4.06966498 |
| 39 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 4.06186322 |
| 40 | regulation of mitochondrial translation (GO:0070129) | 4.03964751 |
| 41 | proton transport (GO:0015992) | 3.98232654 |
| 42 | hydrogen transport (GO:0006818) | 3.90220614 |
| 43 | inner mitochondrial membrane organization (GO:0007007) | 3.87477786 |
| 44 | sequestering of actin monomers (GO:0042989) | 3.84444728 |
| 45 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.72294304 |
| 46 | termination of RNA polymerase III transcription (GO:0006386) | 3.72055128 |
| 47 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.72055128 |
| 48 | respiratory chain complex IV assembly (GO:0008535) | 3.71717367 |
| 49 | oxidative phosphorylation (GO:0006119) | 3.70919986 |
| 50 | cytochrome complex assembly (GO:0017004) | 3.69629620 |
| 51 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 3.54073193 |
| 52 | mRNA catabolic process (GO:0006402) | 3.51120473 |
| 53 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.43072691 |
| 54 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.42821728 |
| 55 | cellular component biogenesis (GO:0044085) | 3.39305936 |
| 56 | intracellular protein transmembrane import (GO:0044743) | 3.32700324 |
| 57 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.30196405 |
| 58 | protein targeting to mitochondrion (GO:0006626) | 3.24957429 |
| 59 | protein-cofactor linkage (GO:0018065) | 3.23425882 |
| 60 | establishment of protein localization to mitochondrion (GO:0072655) | 3.22195280 |
| 61 | nucleoside triphosphate biosynthetic process (GO:0009142) | 3.18972902 |
| 62 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.18743851 |
| 63 | protein localization to mitochondrion (GO:0070585) | 3.16498935 |
| 64 | RNA catabolic process (GO:0006401) | 3.16444132 |
| 65 | behavioral response to nicotine (GO:0035095) | 3.14435343 |
| 66 | mitochondrial transport (GO:0006839) | 3.09223646 |
| 67 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.08150097 |
| 68 | negative regulation of ligase activity (GO:0051352) | 3.07388236 |
| 69 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.07388236 |
| 70 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.06766550 |
| 71 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.06766550 |
| 72 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.03012951 |
| 73 | purine ribonucleoside monophosphate biosynthetic process (GO:0009168) | 2.98955300 |
| 74 | purine nucleoside monophosphate biosynthetic process (GO:0009127) | 2.98955300 |
| 75 | aerobic respiration (GO:0009060) | 2.97811242 |
| 76 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.95938735 |
| 77 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.94553273 |
| 78 | spliceosomal snRNP assembly (GO:0000387) | 2.93830018 |
| 79 | DNA damage response, detection of DNA damage (GO:0042769) | 2.93429268 |
| 80 | rRNA modification (GO:0000154) | 2.92986601 |
| 81 | GTP biosynthetic process (GO:0006183) | 2.92328792 |
| 82 | establishment of protein localization to membrane (GO:0090150) | 2.90192815 |
| 83 | protein targeting (GO:0006605) | 2.89573128 |
| 84 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.88907244 |
| 85 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.88907244 |
| 86 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.88907244 |
| 87 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.85765183 |
| 88 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.85765183 |
| 89 | spliceosomal complex assembly (GO:0000245) | 2.85246612 |
| 90 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.83626455 |
| 91 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.83543622 |
| 92 | pseudouridine synthesis (GO:0001522) | 2.76980067 |
| 93 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.76186337 |
| 94 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.76186337 |
| 95 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.74364102 |
| 96 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.74253527 |
| 97 | chromatin remodeling at centromere (GO:0031055) | 2.71796681 |
| 98 | establishment of protein localization to organelle (GO:0072594) | 2.70246214 |
| 99 | rRNA processing (GO:0006364) | 2.67779029 |
| 100 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.67522988 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.77128129 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.68612360 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 4.51808448 |
| 4 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.93273097 |
| 5 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.43996897 |
| 6 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.21968520 |
| 7 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.18219884 |
| 8 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.17012105 |
| 9 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.09371509 |
| 10 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.01314591 |
| 11 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.87876955 |
| 12 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.60381537 |
| 13 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.57448885 |
| 14 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.53457513 |
| 15 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.38068074 |
| 16 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.37059989 |
| 17 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.34185680 |
| 18 | * VDR_23849224_ChIP-Seq_CD4+_Human | 2.33497666 |
| 19 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.16696584 |
| 20 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.11117731 |
| 21 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.03202438 |
| 22 | TTF2_22483619_ChIP-Seq_HELA_Human | 2.02147820 |
| 23 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.99080959 |
| 24 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.97732453 |
| 25 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.96364041 |
| 26 | VDR_22108803_ChIP-Seq_LS180_Human | 1.95955497 |
| 27 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.86361922 |
| 28 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.84802115 |
| 29 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.83847141 |
| 30 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.79903711 |
| 31 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.79693198 |
| 32 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.69832072 |
| 33 | FUS_26573619_Chip-Seq_HEK293_Human | 1.69553821 |
| 34 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.60401660 |
| 35 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.59157925 |
| 36 | EWS_26573619_Chip-Seq_HEK293_Human | 1.58075013 |
| 37 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.56599787 |
| 38 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.56356283 |
| 39 | * DCP1A_22483619_ChIP-Seq_HELA_Human | 1.56296148 |
| 40 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.50843858 |
| 41 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.44039313 |
| 42 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.42912939 |
| 43 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.42681818 |
| 44 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.39131134 |
| 45 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.37248234 |
| 46 | * GABP_19822575_ChIP-Seq_HepG2_Human | 1.36907375 |
| 47 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.32437009 |
| 48 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.30528106 |
| 49 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.27915427 |
| 50 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.26511709 |
| 51 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.25886660 |
| 52 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.24885288 |
| 53 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.24050736 |
| 54 | * CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.22217877 |
| 55 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.20015784 |
| 56 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.18569818 |
| 57 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.17346906 |
| 58 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.17047899 |
| 59 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.16810681 |
| 60 | * MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.16271996 |
| 61 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.16186037 |
| 62 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.15971423 |
| 63 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.13229179 |
| 64 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.11797511 |
| 65 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.11748437 |
| 66 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.10003378 |
| 67 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.09749759 |
| 68 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.08506668 |
| 69 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.07270642 |
| 70 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.05343808 |
| 71 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.03324817 |
| 72 | P300_19829295_ChIP-Seq_ESCs_Human | 1.03080414 |
| 73 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.02545137 |
| 74 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.01121301 |
| 75 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.00794310 |
| 76 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.00507934 |
| 77 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.00469648 |
| 78 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.98651985 |
| 79 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 0.97033596 |
| 80 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.96993098 |
| 81 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 0.96792710 |
| 82 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.96011171 |
| 83 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.93371192 |
| 84 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.91244720 |
| 85 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.90259177 |
| 86 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.89716769 |
| 87 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.88688931 |
| 88 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.88688931 |
| 89 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.88462445 |
| 90 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.85099913 |
| 91 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.84798651 |
| 92 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.80323046 |
| 93 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.80323046 |
| 94 | NCOR_22424771_ChIP-Seq_293T_Human | 0.79911504 |
| 95 | * AR_20517297_ChIP-Seq_VCAP_Human | 0.79745138 |
| 96 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.78140966 |
| 97 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.77721589 |
| 98 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.76806391 |
| 99 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.76500800 |
| 100 | REST_21632747_ChIP-Seq_MESCs_Mouse | 0.76073936 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 5.60152618 |
| 2 | MP0006292_abnormal_olfactory_placode | 2.91807049 |
| 3 | MP0003136_yellow_coat_color | 2.62504411 |
| 4 | MP0002938_white_spotting | 2.30197200 |
| 5 | MP0003806_abnormal_nucleotide_metabolis | 2.29535994 |
| 6 | MP0003880_abnormal_central_pattern | 2.29478613 |
| 7 | MP0001529_abnormal_vocalization | 2.29459088 |
| 8 | MP0002837_dystrophic_cardiac_calcinosis | 2.22244061 |
| 9 | MP0006072_abnormal_retinal_apoptosis | 2.02922660 |
| 10 | MP0004142_abnormal_muscle_tone | 2.02386274 |
| 11 | MP0000372_irregular_coat_pigmentation | 2.01236314 |
| 12 | MP0003011_delayed_dark_adaptation | 2.00605009 |
| 13 | MP0002638_abnormal_pupillary_reflex | 1.97467824 |
| 14 | MP0003186_abnormal_redox_activity | 1.88242170 |
| 15 | MP0001984_abnormal_olfaction | 1.80689704 |
| 16 | MP0006036_abnormal_mitochondrial_physio | 1.80400451 |
| 17 | MP0000566_synostosis | 1.79975764 |
| 18 | MP0008058_abnormal_DNA_repair | 1.77484139 |
| 19 | MP0002736_abnormal_nociception_after | 1.76642814 |
| 20 | MP0009046_muscle_twitch | 1.75937386 |
| 21 | MP0008789_abnormal_olfactory_epithelium | 1.73851381 |
| 22 | MP0008877_abnormal_DNA_methylation | 1.72097772 |
| 23 | MP0003718_maternal_effect | 1.70911326 |
| 24 | MP0001968_abnormal_touch/_nociception | 1.67227700 |
| 25 | MP0008995_early_reproductive_senescence | 1.67029881 |
| 26 | MP0001905_abnormal_dopamine_level | 1.64963438 |
| 27 | MP0002653_abnormal_ependyma_morphology | 1.64846133 |
| 28 | MP0005084_abnormal_gallbladder_morpholo | 1.64271743 |
| 29 | MP0001485_abnormal_pinna_reflex | 1.63065358 |
| 30 | MP0005551_abnormal_eye_electrophysiolog | 1.55087544 |
| 31 | MP0006276_abnormal_autonomic_nervous | 1.54909543 |
| 32 | MP0002272_abnormal_nervous_system | 1.53836067 |
| 33 | MP0009745_abnormal_behavioral_response | 1.53661480 |
| 34 | MP0006035_abnormal_mitochondrial_morpho | 1.46873094 |
| 35 | MP0002277_abnormal_respiratory_mucosa | 1.44624716 |
| 36 | MP0000631_abnormal_neuroendocrine_gland | 1.44082259 |
| 37 | MP0002102_abnormal_ear_morphology | 1.41369044 |
| 38 | MP0002822_catalepsy | 1.39701358 |
| 39 | MP0003122_maternal_imprinting | 1.39533867 |
| 40 | MP0001293_anophthalmia | 1.38711632 |
| 41 | MP0004145_abnormal_muscle_electrophysio | 1.38071798 |
| 42 | MP0008875_abnormal_xenobiotic_pharmacok | 1.37855911 |
| 43 | MP0010030_abnormal_orbit_morphology | 1.36313902 |
| 44 | MP0005394_taste/olfaction_phenotype | 1.33066823 |
| 45 | MP0005499_abnormal_olfactory_system | 1.33066823 |
| 46 | MP0005253_abnormal_eye_physiology | 1.32660990 |
| 47 | MP0003121_genomic_imprinting | 1.30866067 |
| 48 | MP0004742_abnormal_vestibular_system | 1.30408739 |
| 49 | MP0004133_heterotaxia | 1.30217760 |
| 50 | MP0004147_increased_porphyrin_level | 1.29413576 |
| 51 | MP0002234_abnormal_pharynx_morphology | 1.25733987 |
| 52 | MP0008872_abnormal_physiological_respon | 1.21913454 |
| 53 | MP0002064_seizures | 1.21894392 |
| 54 | MP0002735_abnormal_chemical_nociception | 1.20316079 |
| 55 | MP0001486_abnormal_startle_reflex | 1.19996703 |
| 56 | MP0005423_abnormal_somatic_nervous | 1.17415331 |
| 57 | MP0002734_abnormal_mechanical_nocicepti | 1.16895865 |
| 58 | MP0003693_abnormal_embryo_hatching | 1.16094070 |
| 59 | MP0001986_abnormal_taste_sensitivity | 1.14435225 |
| 60 | MP0003787_abnormal_imprinting | 1.13440702 |
| 61 | MP0005646_abnormal_pituitary_gland | 1.10428403 |
| 62 | MP0002572_abnormal_emotion/affect_behav | 1.08912776 |
| 63 | MP0003938_abnormal_ear_development | 1.06925995 |
| 64 | MP0002095_abnormal_skin_pigmentation | 1.04343459 |
| 65 | MP0001970_abnormal_pain_threshold | 1.04248615 |
| 66 | MP0002557_abnormal_social/conspecific_i | 1.00348108 |
| 67 | MP0002067_abnormal_sensory_capabilities | 1.00297226 |
| 68 | MP0004957_abnormal_blastocyst_morpholog | 1.00277071 |
| 69 | MP0000026_abnormal_inner_ear | 1.00203008 |
| 70 | MP0005645_abnormal_hypothalamus_physiol | 1.00145256 |
| 71 | MP0000049_abnormal_middle_ear | 0.98598793 |
| 72 | MP0000778_abnormal_nervous_system | 0.96981347 |
| 73 | MP0003646_muscle_fatigue | 0.96163479 |
| 74 | MP0002160_abnormal_reproductive_system | 0.94523688 |
| 75 | MP0003315_abnormal_perineum_morphology | 0.94396833 |
| 76 | MP0004215_abnormal_myocardial_fiber | 0.93508962 |
| 77 | MP0003123_paternal_imprinting | 0.89897975 |
| 78 | MP0002752_abnormal_somatic_nervous | 0.88953170 |
| 79 | MP0004885_abnormal_endolymph | 0.87989303 |
| 80 | MP0010386_abnormal_urinary_bladder | 0.87663916 |
| 81 | MP0002751_abnormal_autonomic_nervous | 0.87442509 |
| 82 | MP0003635_abnormal_synaptic_transmissio | 0.86791257 |
| 83 | MP0002210_abnormal_sex_determination | 0.86102882 |
| 84 | MP0003786_premature_aging | 0.85654302 |
| 85 | MP0005195_abnormal_posterior_eye | 0.85508182 |
| 86 | MP0005408_hypopigmentation | 0.85294982 |
| 87 | MP0002733_abnormal_thermal_nociception | 0.85056019 |
| 88 | MP0009697_abnormal_copulation | 0.84773497 |
| 89 | MP0005389_reproductive_system_phenotype | 0.84642266 |
| 90 | MP0003137_abnormal_impulse_conducting | 0.82805621 |
| 91 | MP0001764_abnormal_homeostasis | 0.81845899 |
| 92 | MP0001440_abnormal_grooming_behavior | 0.80277070 |
| 93 | MP0010094_abnormal_chromosome_stability | 0.79900859 |
| 94 | MP0001188_hyperpigmentation | 0.77435676 |
| 95 | MP0001963_abnormal_hearing_physiology | 0.75135960 |
| 96 | MP0002184_abnormal_innervation | 0.74519245 |
| 97 | MP0003283_abnormal_digestive_organ | 0.74349539 |
| 98 | MP0003890_abnormal_embryonic-extraembry | 0.74113656 |
| 99 | MP0002063_abnormal_learning/memory/cond | 0.73884462 |
| 100 | MP0003567_abnormal_fetal_cardiomyocyte | 0.73851407 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 6.13968941 |
| 2 | Abnormal mitochondria in muscle tissue (HP:0008316) | 5.60631362 |
| 3 | Mitochondrial inheritance (HP:0001427) | 5.57820066 |
| 4 | Acute encephalopathy (HP:0006846) | 5.31457082 |
| 5 | Increased hepatocellular lipid droplets (HP:0006565) | 5.16310287 |
| 6 | Progressive macrocephaly (HP:0004481) | 5.13939988 |
| 7 | Increased CSF lactate (HP:0002490) | 4.85053791 |
| 8 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.84012717 |
| 9 | Lipid accumulation in hepatocytes (HP:0006561) | 4.82083799 |
| 10 | Abnormal number of erythroid precursors (HP:0012131) | 4.70433906 |
| 11 | Hepatocellular necrosis (HP:0001404) | 4.66869663 |
| 12 | Reticulocytopenia (HP:0001896) | 4.34462145 |
| 13 | Hepatic necrosis (HP:0002605) | 4.33459231 |
| 14 | Renal Fanconi syndrome (HP:0001994) | 4.27424746 |
| 15 | Macrocytic anemia (HP:0001972) | 4.00861208 |
| 16 | Cerebral edema (HP:0002181) | 3.87380556 |
| 17 | Increased intramyocellular lipid droplets (HP:0012240) | 3.81076309 |
| 18 | 3-Methylglutaconic aciduria (HP:0003535) | 3.78927150 |
| 19 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.31577076 |
| 20 | Exertional dyspnea (HP:0002875) | 3.29504115 |
| 21 | Congenital, generalized hypertrichosis (HP:0004540) | 3.25958317 |
| 22 | Increased muscle lipid content (HP:0009058) | 3.23831666 |
| 23 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.23328907 |
| 24 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.23328907 |
| 25 | Lactic acidosis (HP:0003128) | 3.06361657 |
| 26 | Optic disc pallor (HP:0000543) | 3.04104218 |
| 27 | Respiratory failure (HP:0002878) | 3.00215218 |
| 28 | Pancreatic cysts (HP:0001737) | 2.90728093 |
| 29 | Increased serum lactate (HP:0002151) | 2.88743076 |
| 30 | Pancreatic fibrosis (HP:0100732) | 2.86582984 |
| 31 | Abnormality of renal resorption (HP:0011038) | 2.84741197 |
| 32 | Exercise intolerance (HP:0003546) | 2.84527119 |
| 33 | Pallor (HP:0000980) | 2.83083527 |
| 34 | Leukodystrophy (HP:0002415) | 2.81479018 |
| 35 | Myokymia (HP:0002411) | 2.70092175 |
| 36 | Septo-optic dysplasia (HP:0100842) | 2.69072892 |
| 37 | Abnormality of midbrain morphology (HP:0002418) | 2.68801000 |
| 38 | Molar tooth sign on MRI (HP:0002419) | 2.68801000 |
| 39 | Respiratory difficulties (HP:0002880) | 2.67808717 |
| 40 | True hermaphroditism (HP:0010459) | 2.67250564 |
| 41 | Glycosuria (HP:0003076) | 2.55346684 |
| 42 | Abnormality of urine glucose concentration (HP:0011016) | 2.55346684 |
| 43 | Medial flaring of the eyebrow (HP:0010747) | 2.47028819 |
| 44 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.46846620 |
| 45 | Lethargy (HP:0001254) | 2.43006948 |
| 46 | Nephronophthisis (HP:0000090) | 2.33829319 |
| 47 | Methylmalonic acidemia (HP:0002912) | 2.23402280 |
| 48 | Hyperglycinemia (HP:0002154) | 2.21788150 |
| 49 | CNS demyelination (HP:0007305) | 2.18396814 |
| 50 | X-linked dominant inheritance (HP:0001423) | 2.17601041 |
| 51 | Hyperphosphaturia (HP:0003109) | 2.16694747 |
| 52 | Generalized aminoaciduria (HP:0002909) | 2.15296221 |
| 53 | Sclerocornea (HP:0000647) | 2.11227743 |
| 54 | Methylmalonic aciduria (HP:0012120) | 2.07480453 |
| 55 | Colon cancer (HP:0003003) | 2.07406546 |
| 56 | Gait imbalance (HP:0002141) | 2.05904572 |
| 57 | Aplastic anemia (HP:0001915) | 2.03296463 |
| 58 | Congenital primary aphakia (HP:0007707) | 1.99698702 |
| 59 | Type I transferrin isoform profile (HP:0003642) | 1.98579219 |
| 60 | Absent septum pellucidum (HP:0001331) | 1.98082678 |
| 61 | Abnormality of the labia minora (HP:0012880) | 1.92661131 |
| 62 | Nephrogenic diabetes insipidus (HP:0009806) | 1.88291822 |
| 63 | Absent thumb (HP:0009777) | 1.86543764 |
| 64 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.85098710 |
| 65 | Concave nail (HP:0001598) | 1.83991436 |
| 66 | Emotional lability (HP:0000712) | 1.81468829 |
| 67 | Male pseudohermaphroditism (HP:0000037) | 1.80818993 |
| 68 | Abnormality of the renal medulla (HP:0100957) | 1.80128717 |
| 69 | Optic nerve hypoplasia (HP:0000609) | 1.79603341 |
| 70 | Limb dystonia (HP:0002451) | 1.77336083 |
| 71 | Oral leukoplakia (HP:0002745) | 1.77184944 |
| 72 | Stenosis of the external auditory canal (HP:0000402) | 1.75709177 |
| 73 | Focal motor seizures (HP:0011153) | 1.73715587 |
| 74 | Degeneration of anterior horn cells (HP:0002398) | 1.73120882 |
| 75 | Abnormality of the anterior horn cell (HP:0006802) | 1.73120882 |
| 76 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.72388955 |
| 77 | Abnormal ciliary motility (HP:0012262) | 1.71789873 |
| 78 | Hypothermia (HP:0002045) | 1.70043601 |
| 79 | Congenital stationary night blindness (HP:0007642) | 1.69486008 |
| 80 | Blindness (HP:0000618) | 1.69274647 |
| 81 | Genital tract atresia (HP:0001827) | 1.68286285 |
| 82 | Hyperglycinuria (HP:0003108) | 1.67343518 |
| 83 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.67166537 |
| 84 | Type II lissencephaly (HP:0007260) | 1.66510137 |
| 85 | Vaginal atresia (HP:0000148) | 1.66384117 |
| 86 | Abnormality of serum amino acid levels (HP:0003112) | 1.64741458 |
| 87 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.62282096 |
| 88 | Dicarboxylic aciduria (HP:0003215) | 1.62282096 |
| 89 | Triphalangeal thumb (HP:0001199) | 1.61706660 |
| 90 | Abnormality of the septum pellucidum (HP:0007375) | 1.60306966 |
| 91 | Depressed nasal ridge (HP:0000457) | 1.59992738 |
| 92 | Increased serum pyruvate (HP:0003542) | 1.57046569 |
| 93 | Rib fusion (HP:0000902) | 1.56815515 |
| 94 | Anencephaly (HP:0002323) | 1.56369747 |
| 95 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.56341558 |
| 96 | Pancytopenia (HP:0001876) | 1.56221529 |
| 97 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.55493331 |
| 98 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.55379352 |
| 99 | Abnormality of alanine metabolism (HP:0010916) | 1.55379352 |
| 100 | Hyperalaninemia (HP:0003348) | 1.55379352 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 5.04355319 |
| 2 | STK16 | 3.26245294 |
| 3 | MAP3K12 | 2.68073494 |
| 4 | ZAK | 2.64881203 |
| 5 | NME1 | 2.64153983 |
| 6 | BUB1 | 2.59285130 |
| 7 | VRK1 | 2.55702507 |
| 8 | WNK3 | 2.50810976 |
| 9 | CDC7 | 1.96113484 |
| 10 | TLK1 | 1.95344276 |
| 11 | DYRK2 | 1.94780616 |
| 12 | NUAK1 | 1.86145409 |
| 13 | PBK | 1.79103707 |
| 14 | CDK19 | 1.69542046 |
| 15 | MST4 | 1.67134871 |
| 16 | ADRBK2 | 1.65533518 |
| 17 | BCKDK | 1.65504304 |
| 18 | SRPK1 | 1.64595005 |
| 19 | BMPR1B | 1.63235920 |
| 20 | NME2 | 1.59935278 |
| 21 | MAP4K2 | 1.59175770 |
| 22 | TAF1 | 1.58962358 |
| 23 | PINK1 | 1.45459747 |
| 24 | NEK1 | 1.41568900 |
| 25 | GRK1 | 1.37997682 |
| 26 | CASK | 1.33285181 |
| 27 | FRK | 1.29488326 |
| 28 | PNCK | 1.25066085 |
| 29 | PLK3 | 1.23517845 |
| 30 | EPHB2 | 1.21494625 |
| 31 | WEE1 | 1.20281709 |
| 32 | MAP2K7 | 1.19372772 |
| 33 | TNIK | 1.16549509 |
| 34 | INSRR | 1.14576022 |
| 35 | MAP3K4 | 1.13462500 |
| 36 | PLK4 | 1.10464221 |
| 37 | OXSR1 | 1.04297022 |
| 38 | PRKCG | 1.00068988 |
| 39 | MARK1 | 0.99061683 |
| 40 | EIF2AK1 | 0.97683906 |
| 41 | MAPK13 | 0.96431327 |
| 42 | PASK | 0.95424206 |
| 43 | EPHA4 | 0.94851248 |
| 44 | DYRK3 | 0.94840088 |
| 45 | CSNK1G2 | 0.92891744 |
| 46 | CSNK1G3 | 0.90115489 |
| 47 | OBSCN | 0.90104344 |
| 48 | LIMK1 | 0.88389706 |
| 49 | PLK1 | 0.86893593 |
| 50 | WNK4 | 0.86821142 |
| 51 | PHKG1 | 0.86049316 |
| 52 | PHKG2 | 0.86049316 |
| 53 | MYLK | 0.79257986 |
| 54 | MUSK | 0.78193538 |
| 55 | DAPK3 | 0.76799083 |
| 56 | TRIM28 | 0.76073171 |
| 57 | CSNK1G1 | 0.75418884 |
| 58 | AURKB | 0.73092316 |
| 59 | CSNK2A2 | 0.71701105 |
| 60 | PDK2 | 0.71356638 |
| 61 | MINK1 | 0.71078649 |
| 62 | TTK | 0.70521522 |
| 63 | MKNK1 | 0.68295911 |
| 64 | PLK2 | 0.68287238 |
| 65 | RPS6KA5 | 0.67313869 |
| 66 | PAK3 | 0.66827650 |
| 67 | EIF2AK3 | 0.66739529 |
| 68 | ABL2 | 0.66550422 |
| 69 | CHEK2 | 0.66507550 |
| 70 | GRK7 | 0.66140090 |
| 71 | AURKA | 0.65832727 |
| 72 | ADRBK1 | 0.65604893 |
| 73 | CSNK2A1 | 0.63955745 |
| 74 | MAPK15 | 0.63435623 |
| 75 | GRK5 | 0.62716932 |
| 76 | CCNB1 | 0.61528563 |
| 77 | BRSK2 | 0.61482515 |
| 78 | CDK8 | 0.60326529 |
| 79 | MAPKAPK5 | 0.58055719 |
| 80 | NTRK2 | 0.57044218 |
| 81 | CSNK1A1L | 0.54566625 |
| 82 | LRRK2 | 0.53148471 |
| 83 | ILK | 0.52438744 |
| 84 | PRKCE | 0.51729198 |
| 85 | PRKACA | 0.51436629 |
| 86 | TESK2 | 0.48168491 |
| 87 | MAP2K4 | 0.47623029 |
| 88 | CSNK1E | 0.47363928 |
| 89 | CAMK2A | 0.47122287 |
| 90 | TAOK3 | 0.46108179 |
| 91 | CSNK1A1 | 0.45564244 |
| 92 | ATR | 0.44541645 |
| 93 | NEK2 | 0.43858901 |
| 94 | CAMK1 | 0.42611655 |
| 95 | MAP3K11 | 0.42400719 |
| 96 | TXK | 0.41822190 |
| 97 | DAPK1 | 0.41031496 |
| 98 | TGFBR1 | 0.40122076 |
| 99 | CDK3 | 0.39758465 |
| 100 | PRKG1 | 0.39586354 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 5.54004964 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 5.47955883 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 4.70765700 |
| 4 | Proteasome_Homo sapiens_hsa03050 | 3.68072602 |
| 5 | Huntingtons disease_Homo sapiens_hsa05016 | 3.33178899 |
| 6 | Alzheimers disease_Homo sapiens_hsa05010 | 3.27875963 |
| 7 | Protein export_Homo sapiens_hsa03060 | 2.85644468 |
| 8 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.85380443 |
| 9 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.82612532 |
| 10 | RNA polymerase_Homo sapiens_hsa03020 | 2.66830827 |
| 11 | Homologous recombination_Homo sapiens_hsa03440 | 1.97205638 |
| 12 | Mismatch repair_Homo sapiens_hsa03430 | 1.95632659 |
| 13 | DNA replication_Homo sapiens_hsa03030 | 1.64393443 |
| 14 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.51068349 |
| 15 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.42783665 |
| 16 | Spliceosome_Homo sapiens_hsa03040 | 1.39392957 |
| 17 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.34736715 |
| 18 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.33497192 |
| 19 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.33484208 |
| 20 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.26029111 |
| 21 | Basal transcription factors_Homo sapiens_hsa03022 | 1.23778767 |
| 22 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.20774887 |
| 23 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.17664564 |
| 24 | RNA degradation_Homo sapiens_hsa03018 | 1.17635201 |
| 25 | Nicotine addiction_Homo sapiens_hsa05033 | 1.14259482 |
| 26 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.13667981 |
| 27 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.12157039 |
| 28 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.07151244 |
| 29 | Phototransduction_Homo sapiens_hsa04744 | 1.04788579 |
| 30 | Purine metabolism_Homo sapiens_hsa00230 | 1.04483409 |
| 31 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.03945629 |
| 32 | Base excision repair_Homo sapiens_hsa03410 | 1.03019579 |
| 33 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.01417626 |
| 34 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.96311303 |
| 35 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.93630822 |
| 36 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.89833974 |
| 37 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.87484066 |
| 38 | Peroxisome_Homo sapiens_hsa04146 | 0.85602835 |
| 39 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.84871655 |
| 40 | RNA transport_Homo sapiens_hsa03013 | 0.84572598 |
| 41 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.83955642 |
| 42 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.83594734 |
| 43 | Metabolic pathways_Homo sapiens_hsa01100 | 0.82574844 |
| 44 | Sulfur relay system_Homo sapiens_hsa04122 | 0.80163110 |
| 45 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.76901095 |
| 46 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.72576333 |
| 47 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.71114565 |
| 48 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.71112577 |
| 49 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.70537579 |
| 50 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.70305440 |
| 51 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.67339929 |
| 52 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.64043109 |
| 53 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.63558694 |
| 54 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.61190785 |
| 55 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.60263806 |
| 56 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.59057101 |
| 57 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.56931762 |
| 58 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.53883328 |
| 59 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.51854794 |
| 60 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.51407608 |
| 61 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.48173828 |
| 62 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.47961858 |
| 63 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.46244212 |
| 64 | GABAergic synapse_Homo sapiens_hsa04727 | 0.46076091 |
| 65 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.45404133 |
| 66 | Olfactory transduction_Homo sapiens_hsa04740 | 0.45115412 |
| 67 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.43987638 |
| 68 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.43793408 |
| 69 | Morphine addiction_Homo sapiens_hsa05032 | 0.43551309 |
| 70 | Taste transduction_Homo sapiens_hsa04742 | 0.41317221 |
| 71 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.41105350 |
| 72 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.41047158 |
| 73 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.40370626 |
| 74 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.40140316 |
| 75 | Retinol metabolism_Homo sapiens_hsa00830 | 0.38349779 |
| 76 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.37745362 |
| 77 | Mineral absorption_Homo sapiens_hsa04978 | 0.36867467 |
| 78 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.34669955 |
| 79 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.33924905 |
| 80 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.33768030 |
| 81 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.32257695 |
| 82 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.31773634 |
| 83 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.30409887 |
| 84 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.30402321 |
| 85 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.29979342 |
| 86 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.29066107 |
| 87 | Carbon metabolism_Homo sapiens_hsa01200 | 0.28028302 |
| 88 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.27039682 |
| 89 | Cell cycle_Homo sapiens_hsa04110 | 0.26864128 |
| 90 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.25841166 |
| 91 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.24953272 |
| 92 | Asthma_Homo sapiens_hsa05310 | 0.24628038 |
| 93 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.24496182 |
| 94 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.23971237 |
| 95 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.23151723 |
| 96 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.22586755 |
| 97 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.22390610 |
| 98 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.21742540 |
| 99 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.21390431 |
| 100 | Circadian entrainment_Homo sapiens_hsa04713 | 0.20444147 |

