

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation by symbiont of host defense response (GO:0052509) | 5.80446852 |
| 2 | modulation by symbiont of host defense response (GO:0052031) | 5.80446852 |
| 3 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 5.80446852 |
| 4 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 5.80446852 |
| 5 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 5.80446852 |
| 6 | modulation by symbiont of host immune response (GO:0052553) | 5.80446852 |
| 7 | antigen processing and presentation of endogenous antigen (GO:0019883) | 5.52098777 |
| 8 | immunoglobulin mediated immune response (GO:0016064) | 5.38770661 |
| 9 | regulation of interferon-beta biosynthetic process (GO:0045357) | 4.87982250 |
| 10 | NIK/NF-kappaB signaling (GO:0038061) | 4.77014526 |
| 11 | macrophage activation involved in immune response (GO:0002281) | 4.63823307 |
| 12 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 4.49808893 |
| 13 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.44089611 |
| 14 | detection of bacterium (GO:0016045) | 4.39138860 |
| 15 | positive thymic T cell selection (GO:0045059) | 4.38640071 |
| 16 | response to host immune response (GO:0052572) | 4.36458185 |
| 17 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 4.36458185 |
| 18 | negative regulation of erythrocyte differentiation (GO:0045647) | 4.32564000 |
| 19 | B cell mediated immunity (GO:0019724) | 4.22496252 |
| 20 | detection of other organism (GO:0098543) | 4.19372404 |
| 21 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.16311637 |
| 22 | negative regulation of cell killing (GO:0031342) | 4.11636685 |
| 23 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.11636685 |
| 24 | regulation of antigen processing and presentation (GO:0002577) | 3.91788113 |
| 25 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.91031818 |
| 26 | response to host (GO:0075136) | 3.91031818 |
| 27 | response to host defenses (GO:0052200) | 3.91031818 |
| 28 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.84767212 |
| 29 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.81308816 |
| 30 | B cell receptor signaling pathway (GO:0050853) | 3.75904321 |
| 31 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.71637581 |
| 32 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.69456439 |
| 33 | neutrophil activation involved in immune response (GO:0002283) | 3.58627091 |
| 34 | positive regulation of antigen processing and presentation (GO:0002579) | 3.54278892 |
| 35 | positive regulation of macrophage cytokine production (GO:0060907) | 3.53675257 |
| 36 | microglial cell activation (GO:0001774) | 3.51447282 |
| 37 | regulation of B cell apoptotic process (GO:0002902) | 3.46865270 |
| 38 | negative regulation of B cell apoptotic process (GO:0002903) | 3.44061734 |
| 39 | positive regulation of B cell differentiation (GO:0045579) | 3.40207555 |
| 40 | regulation of mast cell degranulation (GO:0043304) | 3.39770527 |
| 41 | mature B cell differentiation involved in immune response (GO:0002313) | 3.38514974 |
| 42 | mucosal-associated lymphoid tissue development (GO:0048537) | 3.37002715 |
| 43 | Peyers patch development (GO:0048541) | 3.37002715 |
| 44 | detection of external biotic stimulus (GO:0098581) | 3.34994876 |
| 45 | positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:0061081 | 3.29085503 |
| 46 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.22549343 |
| 47 | myeloid cell activation involved in immune response (GO:0002275) | 3.21069269 |
| 48 | chaperone mediated protein folding requiring cofactor (GO:0051085) | 3.12483182 |
| 49 | response to peptidoglycan (GO:0032494) | 3.11815880 |
| 50 | negative thymic T cell selection (GO:0045060) | 3.09101058 |
| 51 | macrophage activation (GO:0042116) | 3.06633632 |
| 52 | negative regulation of myeloid cell apoptotic process (GO:0033033) | 3.06043605 |
| 53 | mannose metabolic process (GO:0006013) | 3.04735904 |
| 54 | positive regulation of type 2 immune response (GO:0002830) | 3.04298892 |
| 55 | regulation of macrophage cytokine production (GO:0010935) | 3.03008893 |
| 56 | negative regulation of phagocytosis (GO:0050765) | 2.99731014 |
| 57 | regulation of mast cell activation involved in immune response (GO:0033006) | 2.98449595 |
| 58 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 2.98448108 |
| 59 | regulation of B cell differentiation (GO:0045577) | 2.95996159 |
| 60 | positive regulation of interferon-gamma biosynthetic process (GO:0045078) | 2.93745774 |
| 61 | mature B cell differentiation (GO:0002335) | 2.93394002 |
| 62 | positive T cell selection (GO:0043368) | 2.92112850 |
| 63 | negative regulation of interleukin-12 production (GO:0032695) | 2.87710332 |
| 64 | regulation of leukocyte degranulation (GO:0043300) | 2.86872055 |
| 65 | actin filament polymerization (GO:0030041) | 2.86613165 |
| 66 | detection of biotic stimulus (GO:0009595) | 2.85266033 |
| 67 | I-kappaB phosphorylation (GO:0007252) | 2.84869989 |
| 68 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 2.83886295 |
| 69 | negative regulation of leukocyte mediated immunity (GO:0002704) | 2.82679254 |
| 70 | regulation of gamma-delta T cell activation (GO:0046643) | 2.81605567 |
| 71 | regulation of type 2 immune response (GO:0002828) | 2.79934505 |
| 72 | pinocytosis (GO:0006907) | 2.78645182 |
| 73 | negative T cell selection (GO:0043383) | 2.77858365 |
| 74 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 2.74487292 |
| 75 | negative regulation of innate immune response (GO:0045824) | 2.72766309 |
| 76 | respiratory burst (GO:0045730) | 2.72094250 |
| 77 | thymic T cell selection (GO:0045061) | 2.71381597 |
| 78 | negative regulation of type 2 immune response (GO:0002829) | 2.70492046 |
| 79 | defense response to protozoan (GO:0042832) | 2.66230058 |
| 80 | leukocyte aggregation (GO:0070486) | 2.65780239 |
| 81 | regulation of mast cell activation (GO:0033003) | 2.65721336 |
| 82 | positive regulation of interferon-alpha production (GO:0032727) | 2.65683314 |
| 83 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.64305872 |
| 84 | cellular hyperosmotic response (GO:0071474) | 2.64166379 |
| 85 | cellular response to type I interferon (GO:0071357) | 2.62457880 |
| 86 | type I interferon signaling pathway (GO:0060337) | 2.62457880 |
| 87 | regulation of superoxide anion generation (GO:0032928) | 2.60975670 |
| 88 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.59498595 |
| 89 | regulation of monocyte differentiation (GO:0045655) | 2.59344271 |
| 90 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 2.59310667 |
| 91 | positive regulation of mast cell activation (GO:0033005) | 2.58576820 |
| 92 | histone H3-K36 demethylation (GO:0070544) | 2.57265913 |
| 93 | response to type I interferon (GO:0034340) | 2.56959587 |
| 94 | T cell selection (GO:0045058) | 2.56371827 |
| 95 | negative regulation of cytokine production involved in immune response (GO:0002719) | 2.56084754 |
| 96 | positive regulation of interferon-beta production (GO:0032728) | 2.53853481 |
| 97 | regulation of interferon-gamma biosynthetic process (GO:0045072) | 2.52447386 |
| 98 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.52121513 |
| 99 | positive regulation of lipoprotein lipase activity (GO:0051006) | 2.51871299 |
| 100 | positive regulation of triglyceride lipase activity (GO:0061365) | 2.51871299 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.14973315 |
| 2 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.80411794 |
| 3 | VDR_21846776_ChIP-Seq_THP-1_Human | 3.37915637 |
| 4 | MYC_22102868_ChIP-Seq_BL_Human | 2.89616429 |
| 5 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.73311869 |
| 6 | LXR_22292898_ChIP-Seq_THP-1_Human | 2.69513576 |
| 7 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.59277343 |
| 8 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.42850811 |
| 9 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.38201665 |
| 10 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 2.36340884 |
| 11 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.34807597 |
| 12 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.31384437 |
| 13 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.25533721 |
| 14 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.24843605 |
| 15 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 2.12324692 |
| 16 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.11807018 |
| 17 | MAF_26560356_Chip-Seq_TH1_Human | 2.04062179 |
| 18 | UTX_26944678_Chip-Seq_JUKART_Human | 2.00773429 |
| 19 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 2.00673554 |
| 20 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.99299003 |
| 21 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.95014954 |
| 22 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.90126132 |
| 23 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.84931856 |
| 24 | MAF_26560356_Chip-Seq_TH2_Human | 1.84656252 |
| 25 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.83807408 |
| 26 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.82805601 |
| 27 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.80538133 |
| 28 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.79518389 |
| 29 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.79258411 |
| 30 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.74855608 |
| 31 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.74325435 |
| 32 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.73017790 |
| 33 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.70320458 |
| 34 | P68_20966046_ChIP-Seq_HELA_Human | 1.69702111 |
| 35 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.69424964 |
| 36 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.68316697 |
| 37 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.65140079 |
| 38 | SPI1_23127762_ChIP-Seq_K562_Human | 1.64612461 |
| 39 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.62536758 |
| 40 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.61231133 |
| 41 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.56619839 |
| 42 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.55870447 |
| 43 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.55211827 |
| 44 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.53984948 |
| 45 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.53557073 |
| 46 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.52933168 |
| 47 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.52458062 |
| 48 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.50637266 |
| 49 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.49431589 |
| 50 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.48950313 |
| 51 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.44996540 |
| 52 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.42814070 |
| 53 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.41005098 |
| 54 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.40168285 |
| 55 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.37231015 |
| 56 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.35986907 |
| 57 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.35463424 |
| 58 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.34327493 |
| 59 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.33950247 |
| 60 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.32081086 |
| 61 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.30860808 |
| 62 | MYB_26560356_Chip-Seq_TH2_Human | 1.30560712 |
| 63 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.30377157 |
| 64 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.28488847 |
| 65 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.26759285 |
| 66 | MYB_26560356_Chip-Seq_TH1_Human | 1.25813294 |
| 67 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.25768522 |
| 68 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.25341771 |
| 69 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 1.23968064 |
| 70 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.23171091 |
| 71 | SPI1_20517297_ChIP-Seq_HL60_Human | 1.22295216 |
| 72 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.21771231 |
| 73 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.20164311 |
| 74 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.19048177 |
| 75 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.18604822 |
| 76 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 1.18374863 |
| 77 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.16775386 |
| 78 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.15872981 |
| 79 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.15217812 |
| 80 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.14927136 |
| 81 | * CTCF_21964334_ChIP-Seq_BJAB-B_Human | 1.14906067 |
| 82 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.13763482 |
| 83 | PHF8_20622854_ChIP-Seq_HELA_Human | 1.11568433 |
| 84 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.11068756 |
| 85 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.11064686 |
| 86 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.10449701 |
| 87 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.09783220 |
| 88 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.09004330 |
| 89 | * CTCF_21964334_Chip-Seq_Bcells_Human | 1.08905468 |
| 90 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.08407452 |
| 91 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.08086716 |
| 92 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.06947019 |
| 93 | ETS1_21867929_ChIP-Seq_TH2_Mouse | 1.06629643 |
| 94 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.05543719 |
| 95 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.04883685 |
| 96 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.04668733 |
| 97 | GATA1_19941826_ChIP-Seq_K562_Human | 1.04207900 |
| 98 | SA1_27219007_Chip-Seq_Bcells_Human | 1.03983049 |
| 99 | SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.02820142 |
| 100 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.02216727 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001835_abnormal_antigen_presentation | 4.08815613 |
| 2 | MP0005058_abnormal_lysosome_morphology | 3.23609623 |
| 3 | MP0003436_decreased_susceptibility_to | 3.03038165 |
| 4 | MP0003303_peritoneal_inflammation | 2.92693426 |
| 5 | MP0005387_immune_system_phenotype | 2.80740218 |
| 6 | MP0001790_abnormal_immune_system | 2.80740218 |
| 7 | MP0003172_abnormal_lysosome_physiology | 2.78168806 |
| 8 | MP0002138_abnormal_hepatobiliary_system | 2.75430170 |
| 9 | MP0000685_abnormal_immune_system | 2.67969444 |
| 10 | MP0003724_increased_susceptibility_to | 2.65344584 |
| 11 | MP0001800_abnormal_humoral_immune | 2.62383052 |
| 12 | MP0005464_abnormal_platelet_physiology | 2.61161306 |
| 13 | MP0005000_abnormal_immune_tolerance | 2.54786137 |
| 14 | MP0005025_abnormal_response_to | 2.54108913 |
| 15 | MP0002419_abnormal_innate_immunity | 2.49569561 |
| 16 | MP0002452_abnormal_antigen_presenting | 2.30139120 |
| 17 | MP0009278_abnormal_bone_marrow | 2.29980700 |
| 18 | MP0002723_abnormal_immune_serum | 2.29760775 |
| 19 | MP0002148_abnormal_hypersensitivity_rea | 2.28575225 |
| 20 | MP0005671_abnormal_response_to | 2.23617229 |
| 21 | MP0002420_abnormal_adaptive_immunity | 2.14686648 |
| 22 | MP0001819_abnormal_immune_cell | 2.12299376 |
| 23 | MP0009785_altered_susceptibility_to | 2.01287468 |
| 24 | MP0009840_abnormal_foam_cell | 1.95958711 |
| 25 | MP0003183_abnormal_peptide_metabolism | 1.91373856 |
| 26 | MP0003191_abnormal_cellular_cholesterol | 1.91178035 |
| 27 | MP0002132_abnormal_respiratory_system | 1.82922985 |
| 28 | MP0006082_CNS_inflammation | 1.82482995 |
| 29 | MP0003300_gastrointestinal_ulcer | 1.67574233 |
| 30 | MP0001545_abnormal_hematopoietic_system | 1.67259285 |
| 31 | MP0005397_hematopoietic_system_phenotyp | 1.67259285 |
| 32 | MP0002396_abnormal_hematopoietic_system | 1.67035540 |
| 33 | MP0000604_amyloidosis | 1.66369193 |
| 34 | MP0000716_abnormal_immune_system | 1.66332765 |
| 35 | MP0002398_abnormal_bone_marrow | 1.66251966 |
| 36 | MP0003075_altered_response_to | 1.66080331 |
| 37 | MP0000465_gastrointestinal_hemorrhage | 1.65662629 |
| 38 | MP0002405_respiratory_system_inflammati | 1.63937410 |
| 39 | MP0000689_abnormal_spleen_morphology | 1.62180119 |
| 40 | MP0003763_abnormal_thymus_physiology | 1.60509313 |
| 41 | MP0005451_abnormal_body_composition | 1.58180427 |
| 42 | MP0003806_abnormal_nucleotide_metabolis | 1.55126525 |
| 43 | MP0008260_abnormal_autophagy | 1.52830790 |
| 44 | MP0004510_myositis | 1.52118499 |
| 45 | MP0001533_abnormal_skeleton_physiology | 1.43308359 |
| 46 | MP0008469_abnormal_protein_level | 1.42177325 |
| 47 | MP0001845_abnormal_inflammatory_respons | 1.41273735 |
| 48 | MP0002429_abnormal_blood_cell | 1.37833535 |
| 49 | MP0009333_abnormal_splenocyte_physiolog | 1.37256415 |
| 50 | MP0002722_abnormal_immune_system | 1.32111662 |
| 51 | MP0002139_abnormal_hepatobiliary_system | 1.26548402 |
| 52 | MP0010155_abnormal_intestine_physiology | 1.20672146 |
| 53 | MP0000343_altered_response_to | 1.19718331 |
| 54 | MP0005310_abnormal_salivary_gland | 1.18678810 |
| 55 | MP0002653_abnormal_ependyma_morphology | 1.18558550 |
| 56 | MP0003329_amyloid_beta_deposits | 1.13932219 |
| 57 | MP0002933_joint_inflammation | 1.08942998 |
| 58 | MP0003690_abnormal_glial_cell | 1.06780000 |
| 59 | MP0003866_abnormal_defecation | 1.06577953 |
| 60 | MP0002998_abnormal_bone_remodeling | 1.05019271 |
| 61 | MP0005365_abnormal_bile_salt | 1.03301560 |
| 62 | MP0002166_altered_tumor_susceptibility | 1.02527627 |
| 63 | MP0005645_abnormal_hypothalamus_physiol | 0.99526958 |
| 64 | MP0005166_decreased_susceptibility_to | 0.98780853 |
| 65 | MP0000015_abnormal_ear_pigmentation | 0.98294841 |
| 66 | MP0006036_abnormal_mitochondrial_physio | 0.96874048 |
| 67 | MP0004947_skin_inflammation | 0.93456791 |
| 68 | MP0004808_abnormal_hematopoietic_stem | 0.91736180 |
| 69 | MP0001853_heart_inflammation | 0.91664680 |
| 70 | MP0000372_irregular_coat_pigmentation | 0.90497986 |
| 71 | MP0003279_aneurysm | 0.88849940 |
| 72 | MP0000858_altered_metastatic_potential | 0.87457268 |
| 73 | MP0002638_abnormal_pupillary_reflex | 0.86274752 |
| 74 | MP0000490_abnormal_crypts_of | 0.84810385 |
| 75 | MP0001873_stomach_inflammation | 0.84644342 |
| 76 | MP0009764_decreased_sensitivity_to | 0.83885193 |
| 77 | MP0003879_abnormal_hair_cell | 0.83546251 |
| 78 | MP0001661_extended_life_span | 0.82411441 |
| 79 | MP0005075_abnormal_melanosome_morpholog | 0.80566763 |
| 80 | MP0009763_increased_sensitivity_to | 0.80393290 |
| 81 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.79924037 |
| 82 | MP0004145_abnormal_muscle_electrophysio | 0.79518089 |
| 83 | MP0000703_abnormal_thymus_morphology | 0.78454564 |
| 84 | MP0003828_pulmonary_edema | 0.78276045 |
| 85 | MP0001348_abnormal_lacrimal_gland | 0.77814057 |
| 86 | MP0008874_decreased_physiological_sensi | 0.74982146 |
| 87 | MP0000747_muscle_weakness | 0.71157071 |
| 88 | MP0000681_abnormal_thyroid_gland | 0.71001814 |
| 89 | MP0005319_abnormal_enzyme/_coenzyme | 0.70764475 |
| 90 | MP0001851_eye_inflammation | 0.69367303 |
| 91 | MP0001849_ear_inflammation | 0.68875547 |
| 92 | MP0001663_abnormal_digestive_system | 0.68803067 |
| 93 | MP0005165_increased_susceptibility_to | 0.68454925 |
| 94 | MP0002118_abnormal_lipid_homeostasis | 0.68371343 |
| 95 | MP0002971_abnormal_brown_adipose | 0.66135789 |
| 96 | MP0010329_abnormal_lipoprotein_level | 0.66047085 |
| 97 | MP0002009_preneoplasia | 0.63929618 |
| 98 | MP0004883_abnormal_blood_vessel | 0.63649306 |
| 99 | MP0000609_abnormal_liver_physiology | 0.63605759 |
| 100 | MP0000249_abnormal_blood_vessel | 0.63542565 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Eczematoid dermatitis (HP:0000976) | 4.47808716 |
| 2 | Agammaglobulinemia (HP:0004432) | 4.23711420 |
| 3 | Abnormality of macrophages (HP:0004311) | 4.10393222 |
| 4 | Cellulitis (HP:0100658) | 3.90605749 |
| 5 | Recurrent abscess formation (HP:0002722) | 3.71055719 |
| 6 | Mediastinal lymphadenopathy (HP:0100721) | 3.62214123 |
| 7 | Abnormality of liposaccharide metabolism (HP:0010968) | 3.61858114 |
| 8 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 3.61858114 |
| 9 | Abnormality of glycolipid metabolism (HP:0010969) | 3.61858114 |
| 10 | Recurrent bacterial skin infections (HP:0005406) | 3.60144916 |
| 11 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.59422404 |
| 12 | Meningitis (HP:0001287) | 3.57613502 |
| 13 | Dysostosis multiplex (HP:0000943) | 3.51398476 |
| 14 | Prolonged bleeding time (HP:0003010) | 3.36920761 |
| 15 | Increased cerebral lipofuscin (HP:0011813) | 3.23756969 |
| 16 | Gastrointestinal stroma tumor (HP:0100723) | 3.20046020 |
| 17 | Obstructive lung disease (HP:0006536) | 3.17542049 |
| 18 | Chronic obstructive pulmonary disease (HP:0006510) | 3.17542049 |
| 19 | Stomatitis (HP:0010280) | 3.13968475 |
| 20 | Purpura (HP:0000979) | 3.13799100 |
| 21 | Petechiae (HP:0000967) | 3.10503180 |
| 22 | Colitis (HP:0002583) | 3.08704337 |
| 23 | Systemic lupus erythematosus (HP:0002725) | 2.96441348 |
| 24 | Gastrointestinal inflammation (HP:0004386) | 2.94564288 |
| 25 | Asymmetric septal hypertrophy (HP:0001670) | 2.89778337 |
| 26 | Rhabdomyolysis (HP:0003201) | 2.89527529 |
| 27 | Inflammation of the large intestine (HP:0002037) | 2.88680084 |
| 28 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.88228139 |
| 29 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.85921270 |
| 30 | Myositis (HP:0100614) | 2.84754706 |
| 31 | Visual hallucinations (HP:0002367) | 2.82071668 |
| 32 | Panhypogammaglobulinemia (HP:0003139) | 2.80259909 |
| 33 | Gingival bleeding (HP:0000225) | 2.74582119 |
| 34 | Epistaxis (HP:0000421) | 2.74054559 |
| 35 | Recurrent fungal infections (HP:0002841) | 2.71356072 |
| 36 | Exercise-induced myalgia (HP:0003738) | 2.70749560 |
| 37 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.69001614 |
| 38 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.60052609 |
| 39 | Fatigue (HP:0012378) | 2.54641185 |
| 40 | Abnormality of skeletal muscle fiber size (HP:0012084) | 2.52012019 |
| 41 | Loss of speech (HP:0002371) | 2.51853299 |
| 42 | Recurrent skin infections (HP:0001581) | 2.51534018 |
| 43 | Prolonged neonatal jaundice (HP:0006579) | 2.50136870 |
| 44 | Urticaria (HP:0001025) | 2.47502771 |
| 45 | Vacuolated lymphocytes (HP:0001922) | 2.45387289 |
| 46 | Progressive neurologic deterioration (HP:0002344) | 2.43976522 |
| 47 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.43061895 |
| 48 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.43061895 |
| 49 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.43061895 |
| 50 | Papilloma (HP:0012740) | 2.41100396 |
| 51 | Verrucae (HP:0200043) | 2.41100396 |
| 52 | Mucopolysacchariduria (HP:0008155) | 2.38726873 |
| 53 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.38726873 |
| 54 | Vasculitis (HP:0002633) | 2.36849517 |
| 55 | Recurrent viral infections (HP:0004429) | 2.36683632 |
| 56 | Global brain atrophy (HP:0002283) | 2.35918857 |
| 57 | Osteomyelitis (HP:0002754) | 2.35592024 |
| 58 | Increased variability in muscle fiber diameter (HP:0003557) | 2.35314686 |
| 59 | Episodic fever (HP:0001954) | 2.34475869 |
| 60 | Chest pain (HP:0100749) | 2.33714914 |
| 61 | Increased IgE level (HP:0003212) | 2.32458129 |
| 62 | Ragged-red muscle fibers (HP:0003200) | 2.32432840 |
| 63 | Hepatosplenomegaly (HP:0001433) | 2.31890884 |
| 64 | Orchitis (HP:0100796) | 2.31768532 |
| 65 | Encephalitis (HP:0002383) | 2.27668688 |
| 66 | Emphysema (HP:0002097) | 2.27093942 |
| 67 | Recurrent pneumonia (HP:0006532) | 2.25988130 |
| 68 | Easy fatigability (HP:0003388) | 2.25045115 |
| 69 | Recurrent bronchitis (HP:0002837) | 2.24755719 |
| 70 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.20900582 |
| 71 | Recurrent cutaneous fungal infections (HP:0011370) | 2.20900582 |
| 72 | Muscle stiffness (HP:0003552) | 2.20340673 |
| 73 | Restrictive lung disease (HP:0002091) | 2.17839553 |
| 74 | Distal lower limb muscle weakness (HP:0009053) | 2.17303946 |
| 75 | Recurrent sinusitis (HP:0011108) | 2.13334059 |
| 76 | Recurrent lower respiratory tract infections (HP:0002783) | 2.11922596 |
| 77 | Sepsis (HP:0100806) | 2.10491532 |
| 78 | Thrombocytosis (HP:0001894) | 2.10060328 |
| 79 | Increased serum ferritin (HP:0003281) | 2.08089584 |
| 80 | Gastrointestinal infarctions (HP:0005244) | 2.05897313 |
| 81 | Lymphopenia (HP:0001888) | 2.05341355 |
| 82 | Amyloidosis (HP:0011034) | 2.03272876 |
| 83 | Neuronal loss in central nervous system (HP:0002529) | 1.97812033 |
| 84 | Polycythemia (HP:0001901) | 1.93869742 |
| 85 | Thoracic kyphosis (HP:0002942) | 1.93355900 |
| 86 | Rapidly progressive (HP:0003678) | 1.91576633 |
| 87 | Hypertensive crisis (HP:0100735) | 1.91099847 |
| 88 | Spontaneous hematomas (HP:0007420) | 1.90972681 |
| 89 | Increased IgM level (HP:0003496) | 1.89504022 |
| 90 | Peripheral hypomyelination (HP:0007182) | 1.88682450 |
| 91 | Nemaline bodies (HP:0003798) | 1.87236995 |
| 92 | Joint stiffness (HP:0001387) | 1.87181553 |
| 93 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 1.87098004 |
| 94 | Gingivitis (HP:0000230) | 1.86094743 |
| 95 | Hyperlipoproteinemia (HP:0010980) | 1.85133747 |
| 96 | Muscle fiber inclusion bodies (HP:0100299) | 1.83664215 |
| 97 | Hematochezia (HP:0002573) | 1.83578898 |
| 98 | Akinesia (HP:0002304) | 1.81854860 |
| 99 | Arterial thrombosis (HP:0004420) | 1.81764068 |
| 100 | Supranuclear gaze palsy (HP:0000605) | 1.81366568 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ERN1 | 4.50926624 |
| 2 | MAP4K1 | 3.67245578 |
| 3 | BLK | 3.19210380 |
| 4 | MAP3K11 | 2.93224013 |
| 5 | RIPK4 | 2.69527203 |
| 6 | IRAK4 | 2.62196427 |
| 7 | BCKDK | 2.43961781 |
| 8 | MAP2K3 | 2.28595183 |
| 9 | PRPF4B | 2.25270354 |
| 10 | TNK2 | 2.13148317 |
| 11 | TESK2 | 1.93604197 |
| 12 | KIT | 1.90203662 |
| 13 | FES | 1.85471424 |
| 14 | TYK2 | 1.83925262 |
| 15 | TBK1 | 1.81802478 |
| 16 | CSF1R | 1.80907635 |
| 17 | TAOK1 | 1.78061747 |
| 18 | SYK | 1.77493648 |
| 19 | TRIB3 | 1.71196649 |
| 20 | KDR | 1.70773555 |
| 21 | ZAP70 | 1.67941569 |
| 22 | TESK1 | 1.65267520 |
| 23 | JAK3 | 1.63998530 |
| 24 | ARAF | 1.61567672 |
| 25 | IKBKE | 1.59936911 |
| 26 | MAP3K13 | 1.54537355 |
| 27 | NME2 | 1.47235339 |
| 28 | BTK | 1.46628188 |
| 29 | MUSK | 1.37258225 |
| 30 | LYN | 1.29402604 |
| 31 | TAOK2 | 1.27292908 |
| 32 | PIM2 | 1.24343507 |
| 33 | SIK2 | 1.17391237 |
| 34 | DYRK1B | 1.16686936 |
| 35 | GRK6 | 1.11636849 |
| 36 | CSK | 1.10023750 |
| 37 | MAPK12 | 1.05019346 |
| 38 | MARK2 | 1.02713739 |
| 39 | MAP3K1 | 1.00565863 |
| 40 | IKBKB | 0.96545701 |
| 41 | MAP3K14 | 0.95953758 |
| 42 | HCK | 0.91898568 |
| 43 | MAPK11 | 0.91137121 |
| 44 | LCK | 0.90837701 |
| 45 | MOS | 0.88769317 |
| 46 | CAMKK2 | 0.85978123 |
| 47 | ITK | 0.85063647 |
| 48 | MATK | 0.84791250 |
| 49 | EEF2K | 0.83960521 |
| 50 | MAP3K3 | 0.82676144 |
| 51 | SIK1 | 0.81810446 |
| 52 | SMG1 | 0.76699748 |
| 53 | BMX | 0.74223682 |
| 54 | PDK1 | 0.73576143 |
| 55 | PDPK1 | 0.73413674 |
| 56 | CDC42BPA | 0.72775029 |
| 57 | CAMKK1 | 0.71928635 |
| 58 | PRKD2 | 0.68730747 |
| 59 | PRKD3 | 0.68696109 |
| 60 | PRKCQ | 0.67164655 |
| 61 | MAPK7 | 0.65791522 |
| 62 | MAP2K6 | 0.64787445 |
| 63 | FGR | 0.62484905 |
| 64 | FLT3 | 0.62143049 |
| 65 | JAK2 | 0.61863831 |
| 66 | TEC | 0.60300407 |
| 67 | JAK1 | 0.58958276 |
| 68 | KSR2 | 0.58842179 |
| 69 | IRAK2 | 0.58543145 |
| 70 | RAF1 | 0.58448899 |
| 71 | MARK3 | 0.57021124 |
| 72 | LRRK2 | 0.55521009 |
| 73 | SIK3 | 0.51792172 |
| 74 | DAPK2 | 0.50916107 |
| 75 | TTN | 0.50068134 |
| 76 | MAP2K1 | 0.49573709 |
| 77 | CDK12 | 0.49537895 |
| 78 | LIMK1 | 0.49502963 |
| 79 | VRK2 | 0.47996780 |
| 80 | MAP3K5 | 0.47254779 |
| 81 | MAP3K8 | 0.45828131 |
| 82 | MAP2K2 | 0.44832056 |
| 83 | TGFBR2 | 0.44157826 |
| 84 | HIPK2 | 0.43397550 |
| 85 | FYN | 0.43372683 |
| 86 | BMPR2 | 0.40471387 |
| 87 | CDK19 | 0.39862861 |
| 88 | PIK3CG | 0.38431666 |
| 89 | PRKD1 | 0.37949197 |
| 90 | MAPKAPK2 | 0.36240083 |
| 91 | MAP3K7 | 0.35881889 |
| 92 | MAPK3 | 0.34571467 |
| 93 | RPS6KC1 | 0.33898204 |
| 94 | RPS6KL1 | 0.33898204 |
| 95 | OBSCN | 0.33629267 |
| 96 | STK11 | 0.32571490 |
| 97 | MAPK4 | 0.32241443 |
| 98 | PRKG2 | 0.32108199 |
| 99 | PIM1 | 0.28395919 |
| 100 | DAPK3 | 0.27884110 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Allograft rejection_Homo sapiens_hsa05330 | 3.78488121 |
| 2 | Asthma_Homo sapiens_hsa05310 | 3.55121580 |
| 3 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.52881522 |
| 4 | Other glycan degradation_Homo sapiens_hsa00511 | 3.43515512 |
| 5 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.36279625 |
| 6 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 3.29196727 |
| 7 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 3.12508896 |
| 8 | Leishmaniasis_Homo sapiens_hsa05140 | 2.99660301 |
| 9 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.98677970 |
| 10 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.56483367 |
| 11 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.55838482 |
| 12 | Viral myocarditis_Homo sapiens_hsa05416 | 2.47178337 |
| 13 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.23203706 |
| 14 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.13322471 |
| 15 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.06192830 |
| 16 | Tuberculosis_Homo sapiens_hsa05152 | 2.01683716 |
| 17 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.86902185 |
| 18 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.85500373 |
| 19 | Lysosome_Homo sapiens_hsa04142 | 1.70954811 |
| 20 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.65085417 |
| 21 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.58130931 |
| 22 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.49580157 |
| 23 | Influenza A_Homo sapiens_hsa05164 | 1.46143498 |
| 24 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.45599026 |
| 25 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.45287836 |
| 26 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.42589286 |
| 27 | Phagosome_Homo sapiens_hsa04145 | 1.42494416 |
| 28 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.42126178 |
| 29 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.11983901 |
| 30 | Pertussis_Homo sapiens_hsa05133 | 1.11264129 |
| 31 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.93852118 |
| 32 | Malaria_Homo sapiens_hsa05144 | 0.90484809 |
| 33 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.89298235 |
| 34 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.88757092 |
| 35 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.87388201 |
| 36 | Platelet activation_Homo sapiens_hsa04611 | 0.84588257 |
| 37 | Measles_Homo sapiens_hsa05162 | 0.84479115 |
| 38 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.83572008 |
| 39 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.83364595 |
| 40 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.83093511 |
| 41 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.79543395 |
| 42 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.77518886 |
| 43 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.74270639 |
| 44 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.73467553 |
| 45 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.72606082 |
| 46 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.68025519 |
| 47 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.67057891 |
| 48 | Salmonella infection_Homo sapiens_hsa05132 | 0.66435195 |
| 49 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.65798462 |
| 50 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.64835585 |
| 51 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.63970978 |
| 52 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.63283665 |
| 53 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.61142740 |
| 54 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.60164759 |
| 55 | Galactose metabolism_Homo sapiens_hsa00052 | 0.59802699 |
| 56 | Hepatitis B_Homo sapiens_hsa05161 | 0.58499002 |
| 57 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.57905348 |
| 58 | Peroxisome_Homo sapiens_hsa04146 | 0.55777632 |
| 59 | HTLV-I infection_Homo sapiens_hsa05166 | 0.54276124 |
| 60 | Endocytosis_Homo sapiens_hsa04144 | 0.51679928 |
| 61 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.51452826 |
| 62 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.50225844 |
| 63 | Hepatitis C_Homo sapiens_hsa05160 | 0.50121603 |
| 64 | Apoptosis_Homo sapiens_hsa04210 | 0.50021768 |
| 65 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.49638861 |
| 66 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.49532405 |
| 67 | Shigellosis_Homo sapiens_hsa05131 | 0.49396699 |
| 68 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.48834174 |
| 69 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.48354890 |
| 70 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.48232703 |
| 71 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.47774660 |
| 72 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.45729539 |
| 73 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.45661680 |
| 74 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.43764575 |
| 75 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.41602052 |
| 76 | Legionellosis_Homo sapiens_hsa05134 | 0.41367940 |
| 77 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.37180212 |
| 78 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.37105382 |
| 79 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.36400102 |
| 80 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.34145180 |
| 81 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.34000486 |
| 82 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.32934138 |
| 83 | Carbon metabolism_Homo sapiens_hsa01200 | 0.30950256 |
| 84 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.30069219 |
| 85 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.29752947 |
| 86 | Insulin resistance_Homo sapiens_hsa04931 | 0.29538295 |
| 87 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.28785377 |
| 88 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.28665026 |
| 89 | Sulfur relay system_Homo sapiens_hsa04122 | 0.27452793 |
| 90 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.26579196 |
| 91 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.23781944 |
| 92 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.22798756 |
| 93 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.19595424 |
| 94 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.17736226 |
| 95 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.17655798 |
| 96 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.16190881 |
| 97 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.15901785 |
| 98 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.15346183 |
| 99 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.15315830 |
| 100 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.14033432 |

