C16ORF96

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pre-miRNA processing (GO:0031054)6.90783093
2regulation of posttranscriptional gene silencing (GO:0060147)6.65395455
3regulation of gene silencing by miRNA (GO:0060964)6.65395455
4regulation of gene silencing by RNA (GO:0060966)6.65395455
5single strand break repair (GO:0000012)5.67825859
6heterochromatin organization (GO:0070828)4.93671036
7chromatin silencing (GO:0006342)4.82920689
8chromosome condensation (GO:0030261)4.62650109
9paraxial mesoderm development (GO:0048339)4.56068747
10negative regulation of histone methylation (GO:0031061)4.36834657
11acrosome reaction (GO:0007340)4.36116816
12convergent extension (GO:0060026)4.21064621
13DNA packaging (GO:0006323)4.03948721
14L-serine metabolic process (GO:0006563)4.01229571
15protein-DNA complex disassembly (GO:0032986)4.00859452
16nucleosome disassembly (GO:0006337)4.00859452
17receptor recycling (GO:0001881)3.93998841
18negative regulation of circadian rhythm (GO:0042754)3.92759944
19regulation of histone H3-K9 methylation (GO:0051570)3.91494329
20negative regulation of gene expression, epigenetic (GO:0045814)3.81306224
21spermatid development (GO:0007286)3.79531647
22sperm motility (GO:0030317)3.77389868
23negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.73979914
24protein K11-linked deubiquitination (GO:0035871)3.69622388
25negative regulation of gene silencing (GO:0060969)3.67983904
26regulation of stem cell maintenance (GO:2000036)3.56570047
27protein K48-linked deubiquitination (GO:0071108)3.48749819
28establishment of apical/basal cell polarity (GO:0035089)3.42642919
29regulation of gene silencing (GO:0060968)3.36151527
30L-alpha-amino acid transmembrane transport (GO:1902475)3.34142441
31microtubule severing (GO:0051013)3.33987880
32outer ear morphogenesis (GO:0042473)3.31681829
33negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.28014727
34negative regulation of translation, ncRNA-mediated (GO:0040033)3.28014727
35regulation of translation, ncRNA-mediated (GO:0045974)3.28014727
36regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.25435132
37fusion of sperm to egg plasma membrane (GO:0007342)3.21810049
38protein localization to kinetochore (GO:0034501)3.21666057
39positive regulation of gene expression, epigenetic (GO:0045815)3.21268180
40negative regulation of mRNA processing (GO:0050686)3.12330843
41peptidyl-lysine dimethylation (GO:0018027)3.03763881
42glycerophospholipid catabolic process (GO:0046475)3.03069750
43planar cell polarity pathway involved in neural tube closure (GO:0090179)3.01583186
44mechanosensory behavior (GO:0007638)3.00761732
45sperm capacitation (GO:0048240)2.97615663
46serine family amino acid biosynthetic process (GO:0009070)2.94795205
47regulation of hair follicle development (GO:0051797)2.92585799
48regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.92526423
49innervation (GO:0060384)2.90136330
50positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.87588549
51establishment or maintenance of monopolar cell polarity (GO:0061339)2.86170005
52establishment of monopolar cell polarity (GO:0061162)2.86170005
53homocysteine metabolic process (GO:0050667)2.85274947
54ncRNA catabolic process (GO:0034661)2.85156012
55regulation of synaptic vesicle exocytosis (GO:2000300)2.83412686
56neuronal stem cell maintenance (GO:0097150)2.82764196
57granulocyte differentiation (GO:0030851)2.82656822
58myoblast migration (GO:0051451)2.80729578
59negative regulation of RNA splicing (GO:0033119)2.80057603
60cardiovascular system development (GO:0072358)2.78776101
61locomotory exploration behavior (GO:0035641)2.78440998
62lysine metabolic process (GO:0006553)2.78359248
63lysine catabolic process (GO:0006554)2.78359248
64body morphogenesis (GO:0010171)2.78192915
65microtubule depolymerization (GO:0007019)2.78105746
66auditory behavior (GO:0031223)2.77924997
67regulation of inclusion body assembly (GO:0090083)2.76235697
68mitotic metaphase plate congression (GO:0007080)2.75824572
69cranial nerve development (GO:0021545)2.75416337
70protein complex localization (GO:0031503)2.75255441
71negative regulation of inclusion body assembly (GO:0090084)2.73931749
72regulation of somitogenesis (GO:0014807)2.72172757
73chromatin assembly (GO:0031497)2.72137497
74arachidonic acid secretion (GO:0050482)2.70966430
75icosanoid secretion (GO:0032309)2.70966430
76histone H4 deacetylation (GO:0070933)2.69830376
77serotonin receptor signaling pathway (GO:0007210)2.69010698
78regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.68133100
79negative regulation of mRNA metabolic process (GO:1903312)2.67844750
80RNA localization (GO:0006403)2.67382539
81regulation of Rab GTPase activity (GO:0032313)2.66367886
82positive regulation of Rab GTPase activity (GO:0032851)2.66367886
83spermatid nucleus differentiation (GO:0007289)2.65734717
84angiogenesis involved in wound healing (GO:0060055)2.64556806
85ATP-dependent chromatin remodeling (GO:0043044)2.62525075
86spliceosomal tri-snRNP complex assembly (GO:0000244)2.62209411
87cellular ketone body metabolic process (GO:0046950)2.61238591
88regulation of chromatin silencing (GO:0031935)2.60947857
89establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)2.60683275
90axon ensheathment in central nervous system (GO:0032291)2.60520580
91central nervous system myelination (GO:0022010)2.60520580
92histone exchange (GO:0043486)2.58389758
93mRNA splice site selection (GO:0006376)2.56826506
94cochlea development (GO:0090102)2.55155904
95response to histamine (GO:0034776)2.53957744
96DNA conformation change (GO:0071103)2.51129873
97regulation of telomere maintenance via telomerase (GO:0032210)2.49739325
98positive regulation of catenin import into nucleus (GO:0035413)2.49690959
99germ cell development (GO:0007281)2.49102296
100microtubule polymerization or depolymerization (GO:0031109)2.46509461

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.63579555
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.88060847
3EZH2_22144423_ChIP-Seq_EOC_Human3.07940724
4HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.01561165
5GATA1_26923725_Chip-Seq_HPCs_Mouse2.57438363
6KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.51939687
7KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.51939687
8KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.51939687
9FOXM1_23109430_ChIP-Seq_U2OS_Human2.36546028
10ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.14542339
11EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.98941375
12ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.98357994
13MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.88600253
14RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.84337913
15HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.82906318
16NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.77682314
17ZFP281_18757296_ChIP-ChIP_E14_Mouse1.74639600
18POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.64749729
19ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.63702998
20NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.61240973
21SOX2_18555785_ChIP-Seq_MESCs_Mouse1.60919675
22SOX2_16153702_ChIP-ChIP_HESCs_Human1.55734315
23E2F4_17652178_ChIP-ChIP_JURKAT_Human1.55474811
24CTCF_27219007_Chip-Seq_Bcells_Human1.52177068
25SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.51480767
26DROSHA_22980978_ChIP-Seq_HELA_Human1.50594318
27IKZF1_21737484_ChIP-ChIP_HCT116_Human1.48505680
28P68_20966046_ChIP-Seq_HELA_Human1.44682948
29STAT6_21828071_ChIP-Seq_BEAS2B_Human1.43042198
30ERG_21242973_ChIP-ChIP_JURKAT_Human1.39646647
31IRF1_19129219_ChIP-ChIP_H3396_Human1.37724087
32E2F1_21310950_ChIP-Seq_MCF-7_Human1.37224585
33POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.35550129
34TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.35550129
35VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.34940921
36MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.33963454
37RBPJ_22232070_ChIP-Seq_NCS_Mouse1.32739937
38CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.31586478
39AR_21572438_ChIP-Seq_LNCaP_Human1.31560769
40MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.31293367
41MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.30364019
42TCF3_18692474_ChIP-Seq_MESCs_Mouse1.30253395
43IGF1R_20145208_ChIP-Seq_DFB_Human1.27398525
44YY1_22570637_ChIP-Seq_MALME-3M_Human1.25455949
45SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.25222069
46LXR_22292898_ChIP-Seq_THP-1_Human1.24019721
47E2F1_17053090_ChIP-ChIP_MCF-7_Human1.23281048
48RUNX1_26923725_Chip-Seq_HPCs_Mouse1.22822707
49WT1_19549856_ChIP-ChIP_CCG9911_Human1.19349102
50MYC_22102868_ChIP-Seq_BL_Human1.19192928
51PHF8_20622854_ChIP-Seq_HELA_Human1.18764618
52GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.18073118
53ERA_21632823_ChIP-Seq_H3396_Human1.16531376
54NANOG_21062744_ChIP-ChIP_HESCs_Human1.11126813
55SMC4_20622854_ChIP-Seq_HELA_Human1.10820619
56ELF1_20517297_ChIP-Seq_JURKAT_Human1.08901359
57KDM2B_26808549_Chip-Seq_DND41_Human1.08855881
58WDR5_24793694_ChIP-Seq_LNCAP_Human1.07389076
59CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.06770587
60FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.04969025
61DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.04331672
62KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.03536139
63* RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.03379483
64POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.02012712
65TP63_19390658_ChIP-ChIP_HaCaT_Human1.01617623
66POU5F1_16518401_ChIP-PET_MESCs_Mouse0.99583139
67* EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.99439373
68CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.99360472
69SOX11_22085726_ChIP-Seq_ESNs_Mouse0.97477505
70TCF3_18692474_ChIP-Seq_MEFs_Mouse0.93855537
71TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.92525870
72REST_21632747_ChIP-Seq_MESCs_Mouse0.92325139
73THAP11_20581084_ChIP-Seq_MESCs_Mouse0.92294572
74POU5F1_18692474_ChIP-Seq_MESCs_Mouse0.91722795
75NANOG_20526341_ChIP-Seq_ESCs_Human0.91575656
76ZFP281_27345836_Chip-Seq_ESCs_Mouse0.91547832
77EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.91260414
78RARA_24833708_ChIP-Seq_LIVER_Mouse0.90518475
79CREB1_26743006_Chip-Seq_LNCaP_Human0.90165238
80RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.89377705
81OCT4_19829295_ChIP-Seq_ESCs_Human0.89103610
82CTCF_20526341_ChIP-Seq_ESCs_Human0.89013141
83PKCTHETA_26484144_Chip-Seq_BREAST_Human0.88570743
84POU5F1_16153702_ChIP-ChIP_HESCs_Human0.87629213
85PRDM14_21183938_ChIP-Seq_MESCs_Mouse0.86628116
86POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.86022626
87SOX2_18692474_ChIP-Seq_MESCs_Mouse0.85470170
88MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.85293495
89SA1_27219007_Chip-Seq_ERYTHROID_Human0.84467508
90KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.83416673
91SPI1_20517297_ChIP-Seq_HL60_Human0.82490231
92EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.81996178
93ELK4_26923725_Chip-Seq_MESODERM_Mouse0.81676207
94FOXP1_21924763_ChIP-Seq_HESCs_Human0.81308556
95SMAD3_21741376_ChIP-Seq_ESCs_Human0.81149971
96KDM2B_26808549_Chip-Seq_K562_Human0.80617130
97TCF7_22412390_ChIP-Seq_EML_Mouse0.80256681
98CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.79916101
99SA1_27219007_Chip-Seq_Bcells_Human0.79589716
100TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.79553980

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003878_abnormal_ear_physiology4.37237631
2MP0005377_hearing/vestibular/ear_phenot4.37237631
3MP0002254_reproductive_system_inflammat3.87756688
4MP0005670_abnormal_white_adipose3.61896777
5MP0005410_abnormal_fertilization3.60560832
6MP0001984_abnormal_olfaction3.07827357
7MP0003122_maternal_imprinting2.92694711
8MP0006292_abnormal_olfactory_placode2.72971813
9MP0008877_abnormal_DNA_methylation2.53873361
10MP0003693_abnormal_embryo_hatching2.48636333
11MP0003136_yellow_coat_color2.42723987
12MP0001293_anophthalmia2.38414269
13MP0003787_abnormal_imprinting2.34700564
14MP0003123_paternal_imprinting2.34546199
15MP0009672_abnormal_birth_weight2.33911509
16MP0001188_hyperpigmentation2.15436308
17MP0003121_genomic_imprinting2.09315151
18MP0002138_abnormal_hepatobiliary_system1.99988022
19MP0001485_abnormal_pinna_reflex1.78242172
20MP0010030_abnormal_orbit_morphology1.72998781
21MP0003698_abnormal_male_reproductive1.71750589
22MP0003111_abnormal_nucleus_morphology1.68952399
23MP0006276_abnormal_autonomic_nervous1.66005514
24MP0004957_abnormal_blastocyst_morpholog1.63355735
25MP0001486_abnormal_startle_reflex1.57346998
26MP0001929_abnormal_gametogenesis1.46475949
27MP0009053_abnormal_anal_canal1.43044122
28MP0001730_embryonic_growth_arrest1.43025255
29MP0003119_abnormal_digestive_system1.39099131
30MP0008932_abnormal_embryonic_tissue1.37357027
31MP0002822_catalepsy1.33710624
32MP0003861_abnormal_nervous_system1.31212735
33MP0005499_abnormal_olfactory_system1.30241348
34MP0005394_taste/olfaction_phenotype1.30241348
35MP0002697_abnormal_eye_size1.30223645
36MP0003183_abnormal_peptide_metabolism1.29963374
37MP0003567_abnormal_fetal_cardiomyocyte1.29198997
38MP0000778_abnormal_nervous_system1.25696287
39MP0010094_abnormal_chromosome_stability1.25262970
40MP0003077_abnormal_cell_cycle1.23433374
41MP0002085_abnormal_embryonic_tissue1.22634751
42MP0002210_abnormal_sex_determination1.20888073
43MP0009703_decreased_birth_body1.20341340
44MP0001672_abnormal_embryogenesis/_devel1.19703096
45MP0005380_embryogenesis_phenotype1.19703096
46MP0004859_abnormal_synaptic_plasticity1.15439392
47MP0002084_abnormal_developmental_patter1.15177391
48MP0003890_abnormal_embryonic-extraembry1.14404507
49MP0000955_abnormal_spinal_cord1.10913679
50MP0002161_abnormal_fertility/fecundity1.09384775
51MP0008789_abnormal_olfactory_epithelium1.08368990
52MP0003984_embryonic_growth_retardation1.07117068
53MP0000428_abnormal_craniofacial_morphol1.07076523
54MP0002233_abnormal_nose_morphology1.05998331
55MP0009278_abnormal_bone_marrow1.04426506
56MP0001286_abnormal_eye_development1.01827285
57MP0008569_lethality_at_weaning1.00991185
58MP0000566_synostosis0.98252606
59MP0002088_abnormal_embryonic_growth/wei0.98152288
60MP0004264_abnormal_extraembryonic_tissu0.97149542
61MP0000049_abnormal_middle_ear0.96901227
62MP0008995_early_reproductive_senescence0.96334255
63MP0002734_abnormal_mechanical_nocicepti0.95257575
64MP0001145_abnormal_male_reproductive0.94620566
65MP0004742_abnormal_vestibular_system0.93595297
66MP0004197_abnormal_fetal_growth/weight/0.93379558
67MP0005310_abnormal_salivary_gland0.93207132
68MP0005666_abnormal_adipose_tissue0.92930603
69MP0002249_abnormal_larynx_morphology0.91414495
70MP0002152_abnormal_brain_morphology0.91391300
71MP0003937_abnormal_limbs/digits/tail_de0.89445469
72MP0000026_abnormal_inner_ear0.88855325
73MP0001697_abnormal_embryo_size0.86413462
74MP0003315_abnormal_perineum_morphology0.86241350
75MP0002092_abnormal_eye_morphology0.86092605
76MP0002089_abnormal_postnatal_growth/wei0.83262144
77MP0000653_abnormal_sex_gland0.83153671
78MP0003718_maternal_effect0.81619412
79MP0001963_abnormal_hearing_physiology0.81183187
80MP0004858_abnormal_nervous_system0.80519027
81MP0003385_abnormal_body_wall0.80508797
82MP0002557_abnormal_social/conspecific_i0.80160601
83MP0002080_prenatal_lethality0.79646879
84MP0008057_abnormal_DNA_replication0.79378108
85MP0004233_abnormal_muscle_weight0.78557834
86MP0002184_abnormal_innervation0.75695534
87MP0004811_abnormal_neuron_physiology0.75251297
88MP0002063_abnormal_learning/memory/cond0.72016204
89MP0003635_abnormal_synaptic_transmissio0.71183219
90MP0003011_delayed_dark_adaptation0.71166956
91MP0009379_abnormal_foot_pigmentation0.70294289
92MP0001970_abnormal_pain_threshold0.68109150
93MP0002882_abnormal_neuron_morphology0.67275505
94MP0002736_abnormal_nociception_after0.66960802
95MP0002272_abnormal_nervous_system0.66001450
96MP0003646_muscle_fatigue0.65962542
97MP0004133_heterotaxia0.65310746
98MP0001968_abnormal_touch/_nociception0.63891670
99MP0005464_abnormal_platelet_physiology0.63334386
100MP0001299_abnormal_eye_distance/0.62755984

Predicted human phenotypes

RankGene SetZ-score
1Hepatoblastoma (HP:0002884)3.67163074
2Colon cancer (HP:0003003)3.59152914
3Septo-optic dysplasia (HP:0100842)3.40438352
4Abnormality of the labia minora (HP:0012880)3.38705533
5Cortical dysplasia (HP:0002539)3.17993848
6Failure to thrive in infancy (HP:0001531)2.88669349
7Severe Myopia (HP:0011003)2.75901709
8Ectopic kidney (HP:0000086)2.69561449
9Impulsivity (HP:0100710)2.63667567
10Chronic hepatic failure (HP:0100626)2.61510942
11High anterior hairline (HP:0009890)2.59781414
12Intestinal fistula (HP:0100819)2.53489087
13Severe visual impairment (HP:0001141)2.52701693
14Partial duplication of thumb phalanx (HP:0009944)2.50589172
15Maternal diabetes (HP:0009800)2.49350129
16Abnormality of the aortic arch (HP:0012303)2.49132559
17Abnormality of the diencephalon (HP:0010662)2.47872137
18Rib fusion (HP:0000902)2.47664917
19Abnormality of cochlea (HP:0000375)2.47255187
20Aplasia/Hypoplasia of the sacrum (HP:0008517)2.42331845
21Rectal fistula (HP:0100590)2.41990523
22Rectovaginal fistula (HP:0000143)2.41990523
23Preaxial foot polydactyly (HP:0001841)2.39287907
24Bony spicule pigmentary retinopathy (HP:0007737)2.37066221
25Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.36743736
26Broad thumb (HP:0011304)2.35382063
27Nephroblastoma (Wilms tumor) (HP:0002667)2.29716708
28Overriding aorta (HP:0002623)2.25788365
29Hyperglycinemia (HP:0002154)2.20704343
30Enlarged penis (HP:0000040)2.18768259
31Absent eyebrow (HP:0002223)2.15401334
32Turricephaly (HP:0000262)2.14514116
33Increased nuchal translucency (HP:0010880)2.14305099
34Obsessive-compulsive behavior (HP:0000722)2.13793596
35Anophthalmia (HP:0000528)2.10545082
36Hypoplastic ischia (HP:0003175)2.08712854
37Hyperglycinuria (HP:0003108)2.07498531
38Stenosis of the external auditory canal (HP:0000402)2.07041042
39Renovascular hypertension (HP:0100817)2.07040513
40Vaginal fistula (HP:0004320)2.06383623
41Morphological abnormality of the inner ear (HP:0011390)2.06098210
42Embryonal renal neoplasm (HP:0011794)2.03894102
43Optic nerve hypoplasia (HP:0000609)2.01484576
44Abnormality of the ischium (HP:0003174)2.00401255
45Trigonocephaly (HP:0000243)2.00234158
46Vitreoretinal degeneration (HP:0000655)1.96368095
47Osteomalacia (HP:0002749)1.94928651
48Abnormal hair whorl (HP:0010721)1.94817126
49Chromosomal breakage induced by crosslinking agents (HP:0003221)1.94798172
50Supernumerary ribs (HP:0005815)1.94057501
51Neonatal hypoglycemia (HP:0001998)1.93485383
52Small hand (HP:0200055)1.93328409
53Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.93137033
54Vertebral clefting (HP:0008428)1.91334128
55Thoracic kyphosis (HP:0002942)1.91093118
56Supernumerary bones of the axial skeleton (HP:0009144)1.88600685
57Choanal stenosis (HP:0000452)1.87299120
58Abnormality of the pubic bones (HP:0003172)1.86932950
59Abnormality of the parathyroid morphology (HP:0011766)1.85085234
60Absent radius (HP:0003974)1.84689270
61Thickened helices (HP:0000391)1.84339120
62Embryonal neoplasm (HP:0002898)1.83404638
63Sleep apnea (HP:0010535)1.80665363
64Hyperacusis (HP:0010780)1.78823106
65Duplication of thumb phalanx (HP:0009942)1.77626669
66Genetic anticipation (HP:0003743)1.77377844
67Abnormality of the fingertips (HP:0001211)1.75819035
68Partial duplication of the phalanx of hand (HP:0009999)1.73137915
69Poor coordination (HP:0002370)1.72002870
70Attenuation of retinal blood vessels (HP:0007843)1.71646561
71Aplasia/Hypoplasia of the sternum (HP:0006714)1.71552010
72Abnormality of the ileum (HP:0001549)1.71001450
73Neoplasm of the oral cavity (HP:0100649)1.69447700
74Meckel diverticulum (HP:0002245)1.69190909
75Poikiloderma (HP:0001029)1.68632310
76Broad phalanges of the hand (HP:0009768)1.68608098
77Agnosia (HP:0010524)1.67896301
78Hyperthyroidism (HP:0000836)1.67840885
79Vertebral arch anomaly (HP:0008438)1.67731120
80Broad finger (HP:0001500)1.67455729
81Aplasia involving forearm bones (HP:0009822)1.67235823
82Absent forearm bone (HP:0003953)1.67235823
83Abnormality of glycine metabolism (HP:0010895)1.65659485
84Abnormality of serine family amino acid metabolism (HP:0010894)1.65659485
85Esophageal atresia (HP:0002032)1.65372997
86Horseshoe kidney (HP:0000085)1.65009924
87Anomalous pulmonary venous return (HP:0010772)1.64410304
88Patellar aplasia (HP:0006443)1.63412520
89Bicornuate uterus (HP:0000813)1.61196488
90Spontaneous abortion (HP:0005268)1.60490020
91Gastrointestinal atresia (HP:0002589)1.60289862
92Delayed epiphyseal ossification (HP:0002663)1.60046086
93Facial hemangioma (HP:0000329)1.59547474
94Elfin facies (HP:0004428)1.59421958
95Abnormality of the calcaneus (HP:0008364)1.58553917
96Hyperkalemia (HP:0002153)1.57953903
97Spina bifida occulta (HP:0003298)1.57258466
98Late onset (HP:0003584)1.57244751
99Broad metatarsal (HP:0001783)1.56754037
100Aplasia/Hypoplasia of the earlobes (HP:0009906)1.56252583

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK166.06886400
2PLK43.86525438
3TRIM283.17011341
4CDK123.07215020
5MAP3K102.76211690
6ICK2.28604339
7EEF2K2.09617084
8MKNK22.09040096
9TYRO32.04963635
10UHMK11.90240350
11WNK31.86285735
12CDC71.84047136
13MKNK11.81703166
14CAMK1G1.75296620
15BRD41.70275447
16BMX1.57149362
17BRAF1.54207120
18CAMK1D1.51610393
19SIK31.36107025
20TTK1.30088117
21PDK21.27385547
22PRKD31.25234663
23DYRK21.18305802
24MAPK151.17188988
25PLK21.10800597
26PLK31.07930427
27CDK41.06149100
28CDK191.04742990
29CHEK21.01872080
30INSRR1.01048857
31NEK20.95737948
32FRK0.95196061
33TNK20.94341531
34FGFR10.93962114
35CHEK10.90939070
36FGFR40.89193416
37DYRK1B0.89130923
38FGFR20.87846541
39RIPK10.87809907
40MARK20.85865054
41PRPF4B0.83498646
42NME10.81196838
43PLK10.79929365
44ALK0.78667820
45NTRK30.78667310
46MARK30.78274933
47PNCK0.78157257
48SMG10.78039086
49CDK20.77899918
50BCR0.76079465
51CDK70.75197885
52MAP3K40.74746692
53BTK0.73982255
54MTOR0.73930963
55NTRK20.72971202
56CDK10.71981496
57CAMK10.71127583
58RPS6KA10.70019152
59PKN10.69813620
60DDR20.69387741
61RPS6KL10.67737646
62RPS6KC10.67737646
63FGR0.67524147
64MAPK100.65449959
65YES10.65380637
66ERBB20.62750827
67GSK3B0.61297156
68SGK2230.61052865
69SGK4940.61052865
70STK110.60710040
71RPS6KA20.60627309
72LATS20.60125088
73PIK3CA0.59515162
74PDPK10.59333247
75PDK10.58598941
76BLK0.58262967
77TSSK60.58069792
78MAP2K20.57387578
79TEC0.56636806
80STK38L0.56625031
81PASK0.55282086
82ARAF0.54809271
83CSNK1E0.54458302
84RPS6KA60.54443320
85EPHA40.54186557
86SIK20.54110280
87TXK0.53234774
88PIM10.52748694
89TAF10.52717333
90TRIB30.52261889
91PRKDC0.51164699
92MINK10.49215027
93FES0.49029129
94ATR0.48842491
95ATM0.47604496
96MAPK140.47241093
97PRKCG0.45800359
98PRKG10.45383123
99TNIK0.45365870
100STK30.44790203

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.91494464
2Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.72717616
3alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.52136149
4Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.48628111
5DNA replication_Homo sapiens_hsa030302.47589582
6Lysine degradation_Homo sapiens_hsa003102.45836695
7mRNA surveillance pathway_Homo sapiens_hsa030152.43426964
8Mismatch repair_Homo sapiens_hsa034302.32397483
9Fat digestion and absorption_Homo sapiens_hsa049752.27525987
10Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.18292937
11Primary bile acid biosynthesis_Homo sapiens_hsa001201.87637803
12RNA transport_Homo sapiens_hsa030131.86860356
13Nicotine addiction_Homo sapiens_hsa050331.85959790
14Linoleic acid metabolism_Homo sapiens_hsa005911.81161378
15Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.75362928
16Hedgehog signaling pathway_Homo sapiens_hsa043401.74915669
17Notch signaling pathway_Homo sapiens_hsa043301.74470945
18Selenocompound metabolism_Homo sapiens_hsa004501.72631698
19Butanoate metabolism_Homo sapiens_hsa006501.70354678
20Cell cycle_Homo sapiens_hsa041101.67531347
21Glycerophospholipid metabolism_Homo sapiens_hsa005641.61159721
22Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.52919625
23Fanconi anemia pathway_Homo sapiens_hsa034601.52522274
24Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.50883031
25Ether lipid metabolism_Homo sapiens_hsa005651.48607741
26Glycerolipid metabolism_Homo sapiens_hsa005611.45104598
27Basal cell carcinoma_Homo sapiens_hsa052171.41776560
28Adherens junction_Homo sapiens_hsa045201.32602062
29Cysteine and methionine metabolism_Homo sapiens_hsa002701.31849007
30Spliceosome_Homo sapiens_hsa030401.26150810
31Hippo signaling pathway_Homo sapiens_hsa043901.25214882
32Arginine and proline metabolism_Homo sapiens_hsa003301.22288585
33Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.19874668
34Arachidonic acid metabolism_Homo sapiens_hsa005901.18712949
35Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.18435457
36Olfactory transduction_Homo sapiens_hsa047401.14545503
37Base excision repair_Homo sapiens_hsa034101.13854007
38Colorectal cancer_Homo sapiens_hsa052101.08423198
39Fatty acid metabolism_Homo sapiens_hsa012121.05253275
40Biosynthesis of amino acids_Homo sapiens_hsa012301.05193646
41Serotonergic synapse_Homo sapiens_hsa047261.03054883
42Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.99914908
43Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.91553702
44Morphine addiction_Homo sapiens_hsa050320.90552456
45Propanoate metabolism_Homo sapiens_hsa006400.90084138
46cAMP signaling pathway_Homo sapiens_hsa040240.89381295
47beta-Alanine metabolism_Homo sapiens_hsa004100.89044627
48Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.88584640
49Fatty acid degradation_Homo sapiens_hsa000710.86759163
50Histidine metabolism_Homo sapiens_hsa003400.85161871
51Oocyte meiosis_Homo sapiens_hsa041140.78967790
52Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.78799303
53Fatty acid biosynthesis_Homo sapiens_hsa000610.76706416
54Tight junction_Homo sapiens_hsa045300.76192877
55Wnt signaling pathway_Homo sapiens_hsa043100.75778528
56Thyroid hormone signaling pathway_Homo sapiens_hsa049190.74739734
57Vitamin digestion and absorption_Homo sapiens_hsa049770.73856600
58Non-homologous end-joining_Homo sapiens_hsa034500.73332256
59Vascular smooth muscle contraction_Homo sapiens_hsa042700.73166322
60One carbon pool by folate_Homo sapiens_hsa006700.71339440
61Homologous recombination_Homo sapiens_hsa034400.70177224
62Platelet activation_Homo sapiens_hsa046110.64869015
63MicroRNAs in cancer_Homo sapiens_hsa052060.64668115
64Phospholipase D signaling pathway_Homo sapiens_hsa040720.64593234
65Pancreatic secretion_Homo sapiens_hsa049720.63876035
66Central carbon metabolism in cancer_Homo sapiens_hsa052300.63578037
67Calcium signaling pathway_Homo sapiens_hsa040200.59517028
68Endometrial cancer_Homo sapiens_hsa052130.58063059
69Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.57159399
70Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.54025726
71Choline metabolism in cancer_Homo sapiens_hsa052310.53958723
72Basal transcription factors_Homo sapiens_hsa030220.53703445
73Pyruvate metabolism_Homo sapiens_hsa006200.51893081
74Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.51598451
75N-Glycan biosynthesis_Homo sapiens_hsa005100.49996351
76GABAergic synapse_Homo sapiens_hsa047270.49746368
77Carbon metabolism_Homo sapiens_hsa012000.48004759
78Tryptophan metabolism_Homo sapiens_hsa003800.47638903
79Insulin signaling pathway_Homo sapiens_hsa049100.46669748
80Glutamatergic synapse_Homo sapiens_hsa047240.46346399
81Taste transduction_Homo sapiens_hsa047420.43025799
82Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.42863185
83Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.41304686
84Ras signaling pathway_Homo sapiens_hsa040140.40640107
85Cholinergic synapse_Homo sapiens_hsa047250.40275531
86Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.39903386
87VEGF signaling pathway_Homo sapiens_hsa043700.39491668
88Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.37374518
89RNA degradation_Homo sapiens_hsa030180.37054015
90Oxytocin signaling pathway_Homo sapiens_hsa049210.36918761
91Melanogenesis_Homo sapiens_hsa049160.36339097
92Thyroid cancer_Homo sapiens_hsa052160.36300053
93Dorso-ventral axis formation_Homo sapiens_hsa043200.33224610
94Type II diabetes mellitus_Homo sapiens_hsa049300.31978216
95Gap junction_Homo sapiens_hsa045400.31294202
96Renin-angiotensin system_Homo sapiens_hsa046140.31245534
97Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.30711066
98Protein digestion and absorption_Homo sapiens_hsa049740.30482088
99Axon guidance_Homo sapiens_hsa043600.30191075
100Bile secretion_Homo sapiens_hsa049760.29702012

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »