C17ORF100

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)6.52117051
2establishment of mitochondrion localization (GO:0051654)5.35824864
3cullin deneddylation (GO:0010388)5.21439022
4protein deneddylation (GO:0000338)4.98285479
5nucleobase catabolic process (GO:0046113)4.92098888
6metallo-sulfur cluster assembly (GO:0031163)4.79014939
7iron-sulfur cluster assembly (GO:0016226)4.79014939
8ubiquinone biosynthetic process (GO:0006744)4.69245519
9ubiquinone metabolic process (GO:0006743)4.69149517
10positive regulation of mitochondrial fission (GO:0090141)4.35782074
11pyrimidine deoxyribonucleotide catabolic process (GO:0009223)4.32392125
12protein polyglutamylation (GO:0018095)4.27795619
13ribonucleoprotein complex disassembly (GO:0032988)4.00105124
14sequestering of actin monomers (GO:0042989)3.93323681
15neuron cell-cell adhesion (GO:0007158)3.91187024
16base-excision repair, AP site formation (GO:0006285)3.89867932
17gamma-aminobutyric acid transport (GO:0015812)3.86775378
18pyrimidine dimer repair (GO:0006290)3.82209686
19regulation of mitochondrial translation (GO:0070129)3.80704331
20quinone biosynthetic process (GO:1901663)3.78199386
21protein insertion into membrane (GO:0051205)3.71019094
22pyrimidine nucleotide catabolic process (GO:0006244)3.70899445
23regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315)3.64311339
24positive regulation of amino acid transport (GO:0051957)3.62584927
25regulation of cilium movement (GO:0003352)3.45169173
26negative regulation of telomere maintenance (GO:0032205)3.40481066
27glycosphingolipid biosynthetic process (GO:0006688)3.39500701
28DNA integration (GO:0015074)3.38503576
29organelle disassembly (GO:1903008)3.35816330
30mitochondrion transport along microtubule (GO:0047497)3.35430606
31establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.35430606
32postsynaptic membrane organization (GO:0001941)3.31162230
33peptidyl-arginine omega-N-methylation (GO:0035247)3.30404230
34protein complex biogenesis (GO:0070271)3.29706903
35nonmotile primary cilium assembly (GO:0035058)3.23740387
36quinone metabolic process (GO:1901661)3.23451204
37mannosylation (GO:0097502)3.23401882
38DNA damage response, detection of DNA damage (GO:0042769)3.23284462
39de novo posttranslational protein folding (GO:0051084)3.19953347
40regulation of feeding behavior (GO:0060259)3.18304010
41mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)3.18052517
42positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021103.18052517
43GPI anchor biosynthetic process (GO:0006506)3.07372765
44mitochondrial respiratory chain complex assembly (GO:0033108)3.07079654
45energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.07076328
46ATP hydrolysis coupled proton transport (GO:0015991)3.07076328
47estrogen biosynthetic process (GO:0006703)3.06569679
48GPI anchor metabolic process (GO:0006505)3.03669519
49pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.00688658
50positive regulation of release of cytochrome c from mitochondria (GO:0090200)2.98300475
51de novo protein folding (GO:0006458)2.96151727
52cholesterol biosynthetic process (GO:0006695)2.95504239
53branched-chain amino acid catabolic process (GO:0009083)2.93824755
54cellular response to leptin stimulus (GO:0044320)2.91756972
55preassembly of GPI anchor in ER membrane (GO:0016254)2.90428025
56glycolipid biosynthetic process (GO:0009247)2.89408287
57behavioral response to nicotine (GO:0035095)2.87726692
58protein localization to synapse (GO:0035418)2.86755088
59deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.84735135
60negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.82688505
61regulation of glutamate secretion (GO:0014048)2.82634873
62calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.81913212
63polyketide metabolic process (GO:0030638)2.81384647
64doxorubicin metabolic process (GO:0044598)2.81384647
65daunorubicin metabolic process (GO:0044597)2.81384647
66deoxyribose phosphate catabolic process (GO:0046386)2.80655370
67DNA double-strand break processing (GO:0000729)2.78362790
68deoxyribonucleotide catabolic process (GO:0009264)2.77328700
69peptidyl-arginine N-methylation (GO:0035246)2.77295694
70peptidyl-arginine methylation (GO:0018216)2.77295694
71regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.76585014
72presynaptic membrane assembly (GO:0097105)2.73382535
73mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.72425806
74mitochondrial respiratory chain complex I assembly (GO:0032981)2.72425806
75NADH dehydrogenase complex assembly (GO:0010257)2.72425806
76proteasome assembly (GO:0043248)2.72097559
77sterol biosynthetic process (GO:0016126)2.70414138
78water-soluble vitamin biosynthetic process (GO:0042364)2.68676702
79regulation of mitochondrial fission (GO:0090140)2.66665381
80synaptic vesicle exocytosis (GO:0016079)2.66107696
81protein localization to cilium (GO:0061512)2.65026655
82pyrimidine-containing compound catabolic process (GO:0072529)2.63892613
83L-methionine salvage (GO:0071267)2.62785022
84L-methionine biosynthetic process (GO:0071265)2.62785022
85amino acid salvage (GO:0043102)2.62785022
86axoneme assembly (GO:0035082)2.62488013
87succinate metabolic process (GO:0006105)2.62214847
88negative regulation of synaptic transmission, GABAergic (GO:0032229)2.61106045
89C-terminal protein lipidation (GO:0006501)2.61043331
90melanosome transport (GO:0032402)2.60110877
91response to leptin (GO:0044321)2.57398964
92establishment of melanosome localization (GO:0032401)2.56657103
93L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.55846496
94respiratory chain complex IV assembly (GO:0008535)2.55735002
95negative regulation of amino acid transport (GO:0051956)2.55463020
96intraciliary transport (GO:0042073)2.55189040
97melanosome localization (GO:0032400)2.55020580
98histone arginine methylation (GO:0034969)2.54306539
99positive regulation of receptor biosynthetic process (GO:0010870)2.51470671
100DNA deamination (GO:0045006)2.49337517

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1NOTCH1_17114293_ChIP-ChIP_T-ALL_Human4.47856145
2IGF1R_20145208_ChIP-Seq_DFB_Human4.24166088
3ZNF274_21170338_ChIP-Seq_K562_Hela3.92915849
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.19856135
5JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.04389650
6TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.99225298
7HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.95664506
8GABP_17652178_ChIP-ChIP_JURKAT_Human2.79519552
9CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.77052059
10ETS1_20019798_ChIP-Seq_JURKAT_Human2.58376245
11E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.56101493
12PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.51502339
13NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.47073782
14HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.39449912
15THAP11_20581084_ChIP-Seq_MESCs_Mouse2.34350098
16MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.33063238
17GABP_19822575_ChIP-Seq_HepG2_Human2.22273236
18GBX2_23144817_ChIP-Seq_PC3_Human2.20444443
19CIITA_25753668_ChIP-Seq_RAJI_Human2.18775686
20YY1_21170310_ChIP-Seq_MESCs_Mouse2.18644194
21VDR_23849224_ChIP-Seq_CD4+_Human2.16077077
22SRF_21415370_ChIP-Seq_HL-1_Mouse2.15705885
23CREB1_15753290_ChIP-ChIP_HEK293T_Human2.13410859
24CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.07635328
25EST1_17652178_ChIP-ChIP_JURKAT_Human2.03739404
26ZFP42_18358816_ChIP-ChIP_MESCs_Mouse2.03264480
27PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.01505090
28HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.96507686
29RNF2_27304074_Chip-Seq_NSC_Mouse1.73248007
30TAF15_26573619_Chip-Seq_HEK293_Human1.71530666
31REST_18959480_ChIP-ChIP_MESCs_Mouse1.70833936
32IRF1_19129219_ChIP-ChIP_H3396_Human1.68493666
33FOXP3_21729870_ChIP-Seq_TREG_Human1.54453816
34YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.50632202
35GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.50214995
36DCP1A_22483619_ChIP-Seq_HELA_Human1.47960286
37CTBP2_25329375_ChIP-Seq_LNCAP_Human1.46643770
38CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.45239754
39ZFP57_27257070_Chip-Seq_ESCs_Mouse1.41508348
40POU3F2_20337985_ChIP-ChIP_501MEL_Human1.37466252
41MYC_18358816_ChIP-ChIP_MESCs_Mouse1.36149230
42FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.35977663
43FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.35925043
44MYC_18940864_ChIP-ChIP_HL60_Human1.33401796
45FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.29205311
46TP53_22573176_ChIP-Seq_HFKS_Human1.28044622
47EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.27912067
48PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.27200305
49E2F1_18555785_ChIP-Seq_MESCs_Mouse1.25492453
50ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.21562839
51NELFA_20434984_ChIP-Seq_ESCs_Mouse1.16252241
52TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.14737850
53CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.14342658
54TTF2_22483619_ChIP-Seq_HELA_Human1.13564283
55CBX2_27304074_Chip-Seq_ESCs_Mouse1.13260265
56ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.11732228
57HOXB4_20404135_ChIP-ChIP_EML_Mouse1.11697876
58MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.11550476
59XRN2_22483619_ChIP-Seq_HELA_Human1.10997452
60VDR_22108803_ChIP-Seq_LS180_Human1.10775153
61REST_21632747_ChIP-Seq_MESCs_Mouse1.09347809
62CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.09138660
63ELK1_19687146_ChIP-ChIP_HELA_Human1.07004588
64BP1_19119308_ChIP-ChIP_Hs578T_Human1.06880824
65CTBP1_25329375_ChIP-Seq_LNCAP_Human1.05575691
66FUS_26573619_Chip-Seq_HEK293_Human1.04726673
67ELF1_17652178_ChIP-ChIP_JURKAT_Human1.03340245
68CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.02976438
69P300_19829295_ChIP-Seq_ESCs_Human1.02598876
70BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.01987480
71MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.00293866
72BCL6_27268052_Chip-Seq_Bcells_Human1.00265975
73EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.00054907
74KDM5A_27292631_Chip-Seq_BREAST_Human0.99079132
75LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.96923756
76EWS_26573619_Chip-Seq_HEK293_Human0.96456517
77POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.96312349
78ETV2_25802403_ChIP-Seq_MESCs_Mouse0.96164826
79YY1_22570637_ChIP-Seq_MALME-3M_Human0.95698074
80EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.95465292
81SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.95385972
82SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.94763719
83EZH2_22144423_ChIP-Seq_EOC_Human0.94348947
84AR_20517297_ChIP-Seq_VCAP_Human0.93710800
85BMI1_23680149_ChIP-Seq_NPCS_Mouse0.93273229
86PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.92983997
87PADI4_21655091_ChIP-ChIP_MCF-7_Human0.90671144
88RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.88921739
89* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.88279981
90* RAC3_21632823_ChIP-Seq_H3396_Human0.88010470
91POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.86536530
92CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.85835554
93ERA_21632823_ChIP-Seq_H3396_Human0.85582832
94CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.83850197
95ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.82751874
96* FOXP1_21924763_ChIP-Seq_HESCs_Human0.82035669
97CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.78038981
98TAL1_26923725_Chip-Seq_HPCs_Mouse0.76729002
99ELF1_20517297_ChIP-Seq_JURKAT_Human0.76515124
100EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.76451139

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002822_catalepsy4.73201046
2MP0001529_abnormal_vocalization4.45296570
3MP0003122_maternal_imprinting3.65891891
4MP0001984_abnormal_olfaction3.21450193
5MP0006276_abnormal_autonomic_nervous2.74651117
6MP0008789_abnormal_olfactory_epithelium2.67752357
7MP0005499_abnormal_olfactory_system2.66917205
8MP0005394_taste/olfaction_phenotype2.66917205
9MP0002653_abnormal_ependyma_morphology2.60647587
10MP0008995_early_reproductive_senescence2.49761202
11MP0004147_increased_porphyrin_level2.45617615
12MP0005645_abnormal_hypothalamus_physiol2.38303460
13MP0004270_analgesia2.26246692
14MP0003880_abnormal_central_pattern2.26103724
15MP0006292_abnormal_olfactory_placode2.12090503
16MP0004859_abnormal_synaptic_plasticity2.07110914
17MP0004142_abnormal_muscle_tone1.96202839
18MP0001986_abnormal_taste_sensitivity1.87884436
19MP0001968_abnormal_touch/_nociception1.79372258
20MP0002736_abnormal_nociception_after1.79021738
21MP0003011_delayed_dark_adaptation1.73366656
22MP0006035_abnormal_mitochondrial_morpho1.72303359
23MP0008058_abnormal_DNA_repair1.68945636
24MP0005253_abnormal_eye_physiology1.63146577
25MP0003121_genomic_imprinting1.63091078
26MP0005423_abnormal_somatic_nervous1.59371417
27MP0001905_abnormal_dopamine_level1.59346224
28MP0008877_abnormal_DNA_methylation1.57325093
29MP0001188_hyperpigmentation1.57066838
30MP0003724_increased_susceptibility_to1.49803509
31MP0009046_muscle_twitch1.45840118
32MP0001764_abnormal_homeostasis1.43866222
33MP0000778_abnormal_nervous_system1.41590326
34MP0004133_heterotaxia1.41093415
35MP0006036_abnormal_mitochondrial_physio1.39671305
36MP0000013_abnormal_adipose_tissue1.39106431
37MP0002572_abnormal_emotion/affect_behav1.36502611
38MP0002751_abnormal_autonomic_nervous1.32799938
39MP0005084_abnormal_gallbladder_morpholo1.32674237
40MP0002734_abnormal_mechanical_nocicepti1.30548376
41MP0000372_irregular_coat_pigmentation1.30169242
42MP0003221_abnormal_cardiomyocyte_apopto1.29721950
43MP0003786_premature_aging1.29065192
44MP0003635_abnormal_synaptic_transmissio1.27137678
45MP0005551_abnormal_eye_electrophysiolog1.25027947
46MP0002735_abnormal_chemical_nociception1.24885740
47MP0006072_abnormal_retinal_apoptosis1.24740576
48MP0000049_abnormal_middle_ear1.22055471
49MP0004811_abnormal_neuron_physiology1.21411383
50MP0002102_abnormal_ear_morphology1.18854823
51MP0002063_abnormal_learning/memory/cond1.13272391
52MP0005646_abnormal_pituitary_gland1.13056109
53MP0000631_abnormal_neuroendocrine_gland1.12566202
54MP0000465_gastrointestinal_hemorrhage1.11975328
55MP0001486_abnormal_startle_reflex1.11245066
56MP0009745_abnormal_behavioral_response1.10447980
57MP0002557_abnormal_social/conspecific_i1.08236181
58MP0002067_abnormal_sensory_capabilities1.05836013
59MP0005167_abnormal_blood-brain_barrier1.02143312
60MP0005386_behavior/neurological_phenoty1.00704923
61MP0004924_abnormal_behavior1.00704923
62MP0002064_seizures1.00433714
63MP0003698_abnormal_male_reproductive1.00003890
64MP0001502_abnormal_circadian_rhythm0.97494493
65MP0008260_abnormal_autophagy0.96780668
66MP0002272_abnormal_nervous_system0.96097572
67MP0002069_abnormal_eating/drinking_beha0.93441716
68MP0001970_abnormal_pain_threshold0.93129825
69MP0005085_abnormal_gallbladder_physiolo0.92341821
70MP0003137_abnormal_impulse_conducting0.91685608
71MP0005075_abnormal_melanosome_morpholog0.90914463
72MP0009697_abnormal_copulation0.90428598
73MP0002882_abnormal_neuron_morphology0.87992296
74MP0002733_abnormal_thermal_nociception0.87042775
75MP0002234_abnormal_pharynx_morphology0.85338557
76MP0004742_abnormal_vestibular_system0.84926980
77MP0000955_abnormal_spinal_cord0.83377010
78MP0002229_neurodegeneration0.82784570
79MP0003787_abnormal_imprinting0.82187445
80MP0005410_abnormal_fertilization0.81166605
81MP0000358_abnormal_cell_content/0.78084824
82MP0003656_abnormal_erythrocyte_physiolo0.77252547
83MP0005391_vision/eye_phenotype0.75715074
84MP0002332_abnormal_exercise_endurance0.75216024
85MP0000639_abnormal_adrenal_gland0.74908800
86MP0002066_abnormal_motor_capabilities/c0.74392347
87MP0001929_abnormal_gametogenesis0.73367596
88MP0002638_abnormal_pupillary_reflex0.73201430
89MP0003329_amyloid_beta_deposits0.72750856
90MP0002752_abnormal_somatic_nervous0.72703767
91MP0010329_abnormal_lipoprotein_level0.69481341
92MP0002090_abnormal_vision0.68749167
93MP0004145_abnormal_muscle_electrophysio0.66152111
94MP0002152_abnormal_brain_morphology0.65906710
95MP0002909_abnormal_adrenal_gland0.63307240
96MP0002184_abnormal_innervation0.63227939
97MP0000653_abnormal_sex_gland0.62619195
98MP0005360_urolithiasis0.60687389
99MP0000647_abnormal_sebaceous_gland0.59715368
100MP0003119_abnormal_digestive_system0.59357665

Predicted human phenotypes

RankGene SetZ-score
1Gait imbalance (HP:0002141)3.82871965
2Congenital primary aphakia (HP:0007707)3.72942098
3Medial flaring of the eyebrow (HP:0010747)3.64348974
4Polyphagia (HP:0002591)3.55808132
5Nephrogenic diabetes insipidus (HP:0009806)3.41161906
6Sensorimotor neuropathy (HP:0007141)3.30354688
7Failure to thrive in infancy (HP:0001531)3.28124457
8Abnormal mitochondria in muscle tissue (HP:0008316)3.04352866
9Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.00785707
10Decreased activity of mitochondrial respiratory chain (HP:0008972)3.00785707
11Retinal dysplasia (HP:0007973)2.96837502
12Split foot (HP:0001839)2.96135467
13Hyperglycinemia (HP:0002154)2.91087721
14Specific learning disability (HP:0001328)2.85268895
15Increased intramyocellular lipid droplets (HP:0012240)2.81025331
16Amyotrophic lateral sclerosis (HP:0007354)2.80542289
17Atrophy/Degeneration involving motor neurons (HP:0007373)2.70918266
18Hepatocellular necrosis (HP:0001404)2.68264351
19Mitochondrial inheritance (HP:0001427)2.68040088
20Acute necrotizing encephalopathy (HP:0006965)2.65668232
21Vaginal atresia (HP:0000148)2.63342920
22Genital tract atresia (HP:0001827)2.61431898
23Acute encephalopathy (HP:0006846)2.58902709
24Hepatic necrosis (HP:0002605)2.58699132
25Increased muscle lipid content (HP:0009058)2.56381305
263-Methylglutaconic aciduria (HP:0003535)2.55354391
27Progressive microcephaly (HP:0000253)2.49586521
28Opisthotonus (HP:0002179)2.46051296
29Lissencephaly (HP:0001339)2.40979273
30Methylmalonic acidemia (HP:0002912)2.38674837
31Spastic diplegia (HP:0001264)2.37913499
32Myokymia (HP:0002411)2.37683937
33Progressive inability to walk (HP:0002505)2.33757129
34Aplasia/Hypoplasia of the brainstem (HP:0007362)2.29736586
35Hypoplasia of the brainstem (HP:0002365)2.29736586
36Abnormality of the lower motor neuron (HP:0002366)2.28871263
37Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.25868096
38Degeneration of the lateral corticospinal tracts (HP:0002314)2.25868096
39Increased CSF lactate (HP:0002490)2.23693966
40Decreased testicular size (HP:0008734)2.23405630
41Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.23241457
42Abnormal protein N-linked glycosylation (HP:0012347)2.23241457
43Abnormal protein glycosylation (HP:0012346)2.23241457
44Abnormal glycosylation (HP:0012345)2.23241457
45Severe combined immunodeficiency (HP:0004430)2.19553334
46Mutism (HP:0002300)2.18065844
47Broad foot (HP:0001769)2.16418315
48Lipid accumulation in hepatocytes (HP:0006561)2.16331547
49Renal Fanconi syndrome (HP:0001994)2.15186327
50Urinary urgency (HP:0000012)2.15045279
51Abnormality of the anterior horn cell (HP:0006802)2.14404972
52Degeneration of anterior horn cells (HP:0002398)2.14404972
53Exercise-induced muscle cramps (HP:0003710)2.12530682
54Increased hepatocellular lipid droplets (HP:0006565)2.11998060
55Poor coordination (HP:0002370)2.10919584
56True hermaphroditism (HP:0010459)2.10419172
57Muscular hypotonia of the trunk (HP:0008936)2.08273786
58Methylmalonic aciduria (HP:0012120)2.08201026
59Abnormal eating behavior (HP:0100738)2.06879998
60Postaxial hand polydactyly (HP:0001162)2.06735695
61Aplasia/hypoplasia of the uterus (HP:0008684)2.06075535
62Abnormality of serine family amino acid metabolism (HP:0010894)2.04605928
63Abnormality of glycine metabolism (HP:0010895)2.04605928
64Inability to walk (HP:0002540)2.04357830
65Lactic acidosis (HP:0003128)2.04167116
66Cerebral hypomyelination (HP:0006808)2.04154583
67Cholecystitis (HP:0001082)2.03792501
68Abnormal gallbladder physiology (HP:0012438)2.03792501
69Delusions (HP:0000746)2.03583371
70Rimmed vacuoles (HP:0003805)2.02086702
71Short tibia (HP:0005736)2.00938016
72Pancreatic cysts (HP:0001737)2.00849733
73Progressive macrocephaly (HP:0004481)1.99604424
74Abnormality of the labia minora (HP:0012880)1.99463124
75Hyperglycinuria (HP:0003108)1.99452876
76Dyskinesia (HP:0100660)1.98713337
77Cortical dysplasia (HP:0002539)1.98148281
78Renal cortical cysts (HP:0000803)1.97371504
79Limb dystonia (HP:0002451)1.95778158
80Pancreatic fibrosis (HP:0100732)1.94666478
81Postaxial foot polydactyly (HP:0001830)1.93059027
82Emotional lability (HP:0000712)1.92594435
83Oligodactyly (hands) (HP:0001180)1.90817774
84Increased serum lactate (HP:0002151)1.88926269
85Type 2 muscle fiber atrophy (HP:0003554)1.88780600
86Polymicrogyria (HP:0002126)1.88662021
87Intention tremor (HP:0002080)1.88408279
88Oligomenorrhea (HP:0000876)1.87836190
89CNS hypomyelination (HP:0003429)1.87283200
90Abnormality of dicarboxylic acid metabolism (HP:0010995)1.85679701
91Dicarboxylic aciduria (HP:0003215)1.85679701
92Pachygyria (HP:0001302)1.84863162
93Generalized aminoaciduria (HP:0002909)1.83104669
94Poor suck (HP:0002033)1.81978071
95Spastic gait (HP:0002064)1.81677096
96Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.80719568
97Abnormality of alanine metabolism (HP:0010916)1.80719568
98Hyperalaninemia (HP:0003348)1.80719568
99Molar tooth sign on MRI (HP:0002419)1.79812287
100Abnormality of midbrain morphology (HP:0002418)1.79812287

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TESK25.03099394
2BCKDK4.05974426
3BCR3.88681607
4MAP4K23.62639062
5MAP2K73.53050951
6TESK13.41365768
7MAP3K43.18994149
8EPHA33.16386409
9LIMK12.56867085
10TRIM282.38049838
11CDK192.35015481
12CSNK1G32.33712232
13PIM22.23551009
14CSNK1A1L2.16757276
15CSNK1G22.12858987
16SRPK12.11342202
17MARK12.01771402
18MAP2K41.98526441
19CSNK1G11.73303007
20CASK1.72985421
21MAPK131.62868735
22RPS6KA41.60263302
23DYRK21.59779454
24ZAK1.48378537
25SCYL21.41238935
26WNK31.41004543
27PINK11.40584459
28CAMKK21.36567119
29ERBB31.20458182
30KDR1.20231025
31ARAF1.18290730
32MAP3K111.16034849
33DYRK31.13918451
34VRK21.13349536
35NUAK11.12286710
36GRK71.03980738
37SIK31.03909586
38CCNB11.03429622
39PRKD30.99516468
40MINK10.93332923
41MAP3K50.88338720
42DYRK1B0.87886108
43RPS6KA50.82835449
44MAP4K10.80147586
45TAOK10.78900014
46PLK20.72436993
47SIK20.71912352
48TNK20.66449404
49GRK60.65387849
50CDK140.63157852
51PAK60.62232562
52CLK10.59387673
53TAOK20.57685139
54FER0.56308938
55FLT30.51757135
56CSF1R0.51036250
57VRK10.49502327
58PDK20.49362188
59PRKCE0.49361995
60ATR0.48807825
61MAP3K60.48189440
62UHMK10.47646716
63PIK3CA0.47334786
64CDK180.43963049
65CDK11A0.43224630
66EIF2AK30.42871385
67RAF10.42848842
68NTRK20.42004553
69AURKA0.41254915
70CAMK2B0.40254737
71CAMK2G0.39952043
72CSNK1A10.38118751
73TAOK30.37007385
74DAPK20.36173752
75CDK150.35239010
76PKN10.32860754
77PAK30.32409080
78ADRBK10.31756704
79CAMK2A0.31509140
80NEK10.31426436
81ITK0.30939464
82MAPK150.30862047
83ADRBK20.30814398
84BMPR1B0.29961378
85DYRK1A0.29957900
86PRKACA0.29698412
87CDK50.29313986
88PRKCG0.28980146
89PRKCZ0.27815392
90DAPK10.27249854
91MAPK90.27131187
92PRKCQ0.26158778
93TLK10.25807079
94PRKAA10.23462255
95MAPKAPK30.22783833
96EPHB10.22244258
97CSNK1D0.22200145
98MAP3K120.19235932
99PRKD10.18594972
100CSNK2A10.18007994

Predicted pathways (KEGG)

RankGene SetZ-score
1Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005633.45811364
2Taurine and hypotaurine metabolism_Homo sapiens_hsa004303.06949419
3Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.98546566
4Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006042.87399231
5Fatty acid elongation_Homo sapiens_hsa000622.53005403
6Oxidative phosphorylation_Homo sapiens_hsa001902.42316099
7Steroid biosynthesis_Homo sapiens_hsa001002.36103138
8Parkinsons disease_Homo sapiens_hsa050122.33183321
9Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.27869528
10Nicotine addiction_Homo sapiens_hsa050332.22727231
11Protein export_Homo sapiens_hsa030602.11128348
12Collecting duct acid secretion_Homo sapiens_hsa049662.04586798
13RNA polymerase_Homo sapiens_hsa030201.98054359
14Proteasome_Homo sapiens_hsa030501.97377114
15Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.92545987
162-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.87925579
17Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.84133068
18Butanoate metabolism_Homo sapiens_hsa006501.80621806
19Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.80278190
20Base excision repair_Homo sapiens_hsa034101.80203605
21Synaptic vesicle cycle_Homo sapiens_hsa047211.76098573
22Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.73709295
23Regulation of autophagy_Homo sapiens_hsa041401.73101179
24Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.69757323
25Peroxisome_Homo sapiens_hsa041461.64477676
26Primary immunodeficiency_Homo sapiens_hsa053401.56254388
27Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.56002812
28GABAergic synapse_Homo sapiens_hsa047271.50520354
29Fatty acid metabolism_Homo sapiens_hsa012121.46670065
30Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.45608676
31Primary bile acid biosynthesis_Homo sapiens_hsa001201.45423801
32Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.42192103
33Sulfur relay system_Homo sapiens_hsa041221.39687295
34Vibrio cholerae infection_Homo sapiens_hsa051101.36650468
35Huntingtons disease_Homo sapiens_hsa050161.31654305
36Propanoate metabolism_Homo sapiens_hsa006401.30161947
37Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.28558225
38Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.20176594
39Phototransduction_Homo sapiens_hsa047441.19977253
40Biosynthesis of amino acids_Homo sapiens_hsa012301.18095921
41Alzheimers disease_Homo sapiens_hsa050101.08214431
42Spliceosome_Homo sapiens_hsa030401.07943720
43Carbon metabolism_Homo sapiens_hsa012001.07871072
44Fanconi anemia pathway_Homo sapiens_hsa034601.06087290
45Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.02967074
46Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.99079903
47Pyrimidine metabolism_Homo sapiens_hsa002400.95351947
48Basal transcription factors_Homo sapiens_hsa030220.94641908
49Metabolic pathways_Homo sapiens_hsa011000.93223250
50Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.84215419
51beta-Alanine metabolism_Homo sapiens_hsa004100.80884836
52Taste transduction_Homo sapiens_hsa047420.80607606
53Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.75840592
54Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.75654699
55Purine metabolism_Homo sapiens_hsa002300.73931623
56Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.72929151
57Steroid hormone biosynthesis_Homo sapiens_hsa001400.71497995
58Shigellosis_Homo sapiens_hsa051310.70871250
59Salmonella infection_Homo sapiens_hsa051320.70543182
60Olfactory transduction_Homo sapiens_hsa047400.69219227
61N-Glycan biosynthesis_Homo sapiens_hsa005100.68566457
62Oocyte meiosis_Homo sapiens_hsa041140.68248201
63Phagosome_Homo sapiens_hsa041450.66417728
64Fructose and mannose metabolism_Homo sapiens_hsa000510.66240772
65Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.63866005
66Cysteine and methionine metabolism_Homo sapiens_hsa002700.60022835
67Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.58675158
68Morphine addiction_Homo sapiens_hsa050320.58529197
69RNA degradation_Homo sapiens_hsa030180.57030921
70Galactose metabolism_Homo sapiens_hsa000520.55023473
71Arginine and proline metabolism_Homo sapiens_hsa003300.54921630
72Folate biosynthesis_Homo sapiens_hsa007900.53214819
73Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.52999641
74Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.51760340
75Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.51403421
76Dopaminergic synapse_Homo sapiens_hsa047280.50588921
77Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.50411599
78Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.47647995
79Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.47122333
80Cardiac muscle contraction_Homo sapiens_hsa042600.46473681
81Phenylalanine metabolism_Homo sapiens_hsa003600.44421652
82SNARE interactions in vesicular transport_Homo sapiens_hsa041300.44012446
83Homologous recombination_Homo sapiens_hsa034400.43872378
84alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.42232765
85Pyruvate metabolism_Homo sapiens_hsa006200.41569597
86Renin-angiotensin system_Homo sapiens_hsa046140.39526988
87Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.39353041
88Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.38872345
89Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.38152955
90RNA transport_Homo sapiens_hsa030130.36381344
91Pentose phosphate pathway_Homo sapiens_hsa000300.36314404
92Pentose and glucuronate interconversions_Homo sapiens_hsa000400.36266954
93Non-homologous end-joining_Homo sapiens_hsa034500.35494826
94Fatty acid degradation_Homo sapiens_hsa000710.32841826
95Sulfur metabolism_Homo sapiens_hsa009200.32366120
96Nucleotide excision repair_Homo sapiens_hsa034200.31786530
97Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.31758736
98Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.31740520
99Tyrosine metabolism_Homo sapiens_hsa003500.31648061
100Ether lipid metabolism_Homo sapiens_hsa005650.30524337

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »