

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 6.16515095 |
| 2 | negative regulation of cell killing (GO:0031342) | 6.16515095 |
| 3 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 6.07123075 |
| 4 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.94799284 |
| 5 | antigen processing and presentation of endogenous antigen (GO:0019883) | 5.90810143 |
| 6 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.88734928 |
| 7 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 5.63947644 |
| 8 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 4.88865448 |
| 9 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 4.88865448 |
| 10 | modulation by symbiont of host immune response (GO:0052553) | 4.88865448 |
| 11 | positive regulation by symbiont of host defense response (GO:0052509) | 4.88865448 |
| 12 | modulation by symbiont of host defense response (GO:0052031) | 4.88865448 |
| 13 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 4.88865448 |
| 14 | detection of bacterium (GO:0016045) | 4.60337946 |
| 15 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.58157733 |
| 16 | detection of other organism (GO:0098543) | 4.55364797 |
| 17 | leukocyte aggregation (GO:0070486) | 4.51254772 |
| 18 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.44869279 |
| 19 | immunoglobulin mediated immune response (GO:0016064) | 4.37711738 |
| 20 | neutrophil activation involved in immune response (GO:0002283) | 4.37395100 |
| 21 | regulation of gamma-delta T cell activation (GO:0046643) | 4.36947903 |
| 22 | macrophage activation involved in immune response (GO:0002281) | 4.28986678 |
| 23 | response to type I interferon (GO:0034340) | 3.99436948 |
| 24 | type I interferon signaling pathway (GO:0060337) | 3.98985744 |
| 25 | cellular response to type I interferon (GO:0071357) | 3.98985744 |
| 26 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.95941420 |
| 27 | response to peptidoglycan (GO:0032494) | 3.93907774 |
| 28 | negative regulation of interleukin-12 production (GO:0032695) | 3.89752029 |
| 29 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.89709839 |
| 30 | response to interleukin-15 (GO:0070672) | 3.88559370 |
| 31 | B cell receptor signaling pathway (GO:0050853) | 3.88060388 |
| 32 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 3.86003151 |
| 33 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.82941147 |
| 34 | negative thymic T cell selection (GO:0045060) | 3.81657309 |
| 35 | positive thymic T cell selection (GO:0045059) | 3.73503072 |
| 36 | detection of external biotic stimulus (GO:0098581) | 3.70315703 |
| 37 | negative T cell selection (GO:0043383) | 3.65713147 |
| 38 | cellular extravasation (GO:0045123) | 3.61670802 |
| 39 | respiratory burst (GO:0045730) | 3.61142573 |
| 40 | regulation of B cell differentiation (GO:0045577) | 3.60863434 |
| 41 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.60552640 |
| 42 | positive regulation of B cell differentiation (GO:0045579) | 3.56593802 |
| 43 | cellular response to interleukin-15 (GO:0071350) | 3.55765155 |
| 44 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.53922155 |
| 45 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.53079160 |
| 46 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.52961575 |
| 47 | defense response to protozoan (GO:0042832) | 3.47657676 |
| 48 | neutrophil activation (GO:0042119) | 3.43413749 |
| 49 | B cell mediated immunity (GO:0019724) | 3.40239723 |
| 50 | regulation of T cell tolerance induction (GO:0002664) | 3.39791686 |
| 51 | germinal center formation (GO:0002467) | 3.38306527 |
| 52 | negative regulation of T cell mediated immunity (GO:0002710) | 3.37751364 |
| 53 | T cell migration (GO:0072678) | 3.37352969 |
| 54 | thymic T cell selection (GO:0045061) | 3.36686128 |
| 55 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.33739164 |
| 56 | response to host immune response (GO:0052572) | 3.33739164 |
| 57 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.32933027 |
| 58 | regulation of antigen processing and presentation (GO:0002577) | 3.32074426 |
| 59 | T cell selection (GO:0045058) | 3.30997364 |
| 60 | negative regulation of phagocytosis (GO:0050765) | 3.30944429 |
| 61 | myeloid cell activation involved in immune response (GO:0002275) | 3.28568099 |
| 62 | NIK/NF-kappaB signaling (GO:0038061) | 3.27952810 |
| 63 | regulation of mast cell degranulation (GO:0043304) | 3.27862810 |
| 64 | positive regulation of antigen processing and presentation (GO:0002579) | 3.24790823 |
| 65 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.24790716 |
| 66 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.23537353 |
| 67 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.23332432 |
| 68 | negative regulation of innate immune response (GO:0045824) | 3.23271245 |
| 69 | response to muramyl dipeptide (GO:0032495) | 3.22095607 |
| 70 | detection of biotic stimulus (GO:0009595) | 3.22081309 |
| 71 | response to protozoan (GO:0001562) | 3.19421125 |
| 72 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.17587828 |
| 73 | regulation of natural killer cell mediated immunity (GO:0002715) | 3.16036916 |
| 74 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 3.16036916 |
| 75 | granulocyte activation (GO:0036230) | 3.15208074 |
| 76 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.11984474 |
| 77 | positive T cell selection (GO:0043368) | 3.11728757 |
| 78 | leukocyte migration involved in inflammatory response (GO:0002523) | 3.11215753 |
| 79 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.10400388 |
| 80 | microglial cell activation (GO:0001774) | 3.09524596 |
| 81 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.08815064 |
| 82 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.08815064 |
| 83 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 3.08639355 |
| 84 | response to host (GO:0075136) | 3.07719392 |
| 85 | response to host defenses (GO:0052200) | 3.07719392 |
| 86 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.07719392 |
| 87 | tolerance induction (GO:0002507) | 3.06186500 |
| 88 | regulation of tolerance induction (GO:0002643) | 3.05798164 |
| 89 | detection of molecule of bacterial origin (GO:0032490) | 3.05036791 |
| 90 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.02751870 |
| 91 | negative regulation of alpha-beta T cell activation (GO:0046636) | 2.99633739 |
| 92 | regulation of mast cell activation involved in immune response (GO:0033006) | 2.96260738 |
| 93 | regulation of regulatory T cell differentiation (GO:0045589) | 2.95583899 |
| 94 | positive regulation of interferon-alpha production (GO:0032727) | 2.95140480 |
| 95 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 2.94574049 |
| 96 | leukocyte degranulation (GO:0043299) | 2.92338251 |
| 97 | regulation of leukocyte degranulation (GO:0043300) | 2.91673250 |
| 98 | negative regulation of cytokine production involved in immune response (GO:0002719) | 2.88931144 |
| 99 | macrophage activation (GO:0042116) | 2.87491279 |
| 100 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 2.86211607 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.22005459 |
| 2 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.49745896 |
| 3 | VDR_21846776_ChIP-Seq_THP-1_Human | 3.48137186 |
| 4 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.34180294 |
| 5 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.22520884 |
| 6 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.20151313 |
| 7 | MYC_22102868_ChIP-Seq_BL_Human | 3.05137847 |
| 8 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.76734731 |
| 9 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.68961627 |
| 10 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.57700336 |
| 11 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.55461887 |
| 12 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.54373671 |
| 13 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.52958307 |
| 14 | * E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.51472271 |
| 15 | * MAF_26560356_Chip-Seq_TH1_Human | 2.51405187 |
| 16 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.44488286 |
| 17 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.35636020 |
| 18 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.34657244 |
| 19 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.33311683 |
| 20 | * UTX_26944678_Chip-Seq_JUKART_Human | 2.32604131 |
| 21 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.24552183 |
| 22 | * KDM2B_26808549_Chip-Seq_SUP-B15_Human | 2.20072197 |
| 23 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.20067279 |
| 24 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.14941632 |
| 25 | MYB_26560356_Chip-Seq_TH2_Human | 2.13085963 |
| 26 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 2.12837826 |
| 27 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 2.10497349 |
| 28 | SPI1_23127762_ChIP-Seq_K562_Human | 2.10310421 |
| 29 | MAF_26560356_Chip-Seq_TH2_Human | 2.09817533 |
| 30 | * LXR_22292898_ChIP-Seq_THP-1_Human | 2.05363241 |
| 31 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.05123131 |
| 32 | TCF7_22412390_ChIP-Seq_EML_Mouse | 2.01326753 |
| 33 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.98332357 |
| 34 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.97364896 |
| 35 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.92052459 |
| 36 | MYB_26560356_Chip-Seq_TH1_Human | 1.91778227 |
| 37 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.90504443 |
| 38 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.90243870 |
| 39 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.86979284 |
| 40 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.85420106 |
| 41 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.79325796 |
| 42 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.75874103 |
| 43 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.75576555 |
| 44 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.71947087 |
| 45 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.67547167 |
| 46 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.66167411 |
| 47 | * KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.66139847 |
| 48 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.64111456 |
| 49 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.55538290 |
| 50 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.52806921 |
| 51 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.52320946 |
| 52 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.47712071 |
| 53 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.47474018 |
| 54 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.44129103 |
| 55 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.42870302 |
| 56 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.42737462 |
| 57 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.39270844 |
| 58 | * ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.39142365 |
| 59 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.38971660 |
| 60 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.38055931 |
| 61 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.37189800 |
| 62 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.34568654 |
| 63 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.34381475 |
| 64 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.33700560 |
| 65 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.33312054 |
| 66 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.32618190 |
| 67 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.31516415 |
| 68 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.31477242 |
| 69 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.31334988 |
| 70 | P68_20966046_ChIP-Seq_HELA_Human | 1.26590627 |
| 71 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.25746680 |
| 72 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.25474240 |
| 73 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.23791437 |
| 74 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.22397373 |
| 75 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.22301018 |
| 76 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.21424222 |
| 77 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.21034270 |
| 78 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.19912581 |
| 79 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.19587306 |
| 80 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.16984680 |
| 81 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.15991042 |
| 82 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.15457232 |
| 83 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.13537614 |
| 84 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.10245988 |
| 85 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.08395094 |
| 86 | GATA3_26560356_Chip-Seq_TH2_Human | 1.03085980 |
| 87 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.02206607 |
| 88 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.02176073 |
| 89 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 1.01678437 |
| 90 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.00650682 |
| 91 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 1.00314667 |
| 92 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.00225599 |
| 93 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.99253405 |
| 94 | GATA1_19941826_ChIP-Seq_K562_Human | 0.98908256 |
| 95 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.98069501 |
| 96 | CTCF_21964334_ChIP-Seq_BJAB-B_Human | 0.97404523 |
| 97 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.96392942 |
| 98 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.94907703 |
| 99 | GATA1_22025678_ChIP-Seq_K562_Human | 0.93360814 |
| 100 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.90729169 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003436_decreased_susceptibility_to | 4.17926458 |
| 2 | MP0001835_abnormal_antigen_presentation | 3.99911808 |
| 3 | MP0003724_increased_susceptibility_to | 3.94932668 |
| 4 | MP0003303_peritoneal_inflammation | 3.50230957 |
| 5 | MP0005671_abnormal_response_to | 3.47966193 |
| 6 | MP0005387_immune_system_phenotype | 3.24250000 |
| 7 | MP0001790_abnormal_immune_system | 3.24250000 |
| 8 | MP0000685_abnormal_immune_system | 3.22775636 |
| 9 | MP0001800_abnormal_humoral_immune | 3.14214426 |
| 10 | MP0005000_abnormal_immune_tolerance | 3.02496227 |
| 11 | MP0005025_abnormal_response_to | 2.97665288 |
| 12 | MP0002419_abnormal_innate_immunity | 2.94587082 |
| 13 | MP0003763_abnormal_thymus_physiology | 2.86568369 |
| 14 | MP0009785_altered_susceptibility_to | 2.84160711 |
| 15 | MP0002723_abnormal_immune_serum | 2.73306053 |
| 16 | MP0002452_abnormal_antigen_presenting | 2.66069979 |
| 17 | MP0002420_abnormal_adaptive_immunity | 2.65335473 |
| 18 | MP0001819_abnormal_immune_cell | 2.62830527 |
| 19 | MP0002148_abnormal_hypersensitivity_rea | 2.44492618 |
| 20 | MP0006082_CNS_inflammation | 2.42722706 |
| 21 | MP0003300_gastrointestinal_ulcer | 2.32527719 |
| 22 | MP0002398_abnormal_bone_marrow | 2.11870166 |
| 23 | MP0009333_abnormal_splenocyte_physiolog | 2.10155653 |
| 24 | MP0000716_abnormal_immune_system | 2.06970159 |
| 25 | MP0010155_abnormal_intestine_physiology | 2.05669010 |
| 26 | MP0001533_abnormal_skeleton_physiology | 2.01922845 |
| 27 | MP0003172_abnormal_lysosome_physiology | 2.01587517 |
| 28 | MP0002405_respiratory_system_inflammati | 2.01504590 |
| 29 | MP0005464_abnormal_platelet_physiology | 2.00269520 |
| 30 | MP0009278_abnormal_bone_marrow | 1.95894926 |
| 31 | MP0005058_abnormal_lysosome_morphology | 1.87110771 |
| 32 | MP0008260_abnormal_autophagy | 1.86304631 |
| 33 | MP0003191_abnormal_cellular_cholesterol | 1.84635279 |
| 34 | MP0001845_abnormal_inflammatory_respons | 1.82007044 |
| 35 | MP0000689_abnormal_spleen_morphology | 1.77047150 |
| 36 | MP0002396_abnormal_hematopoietic_system | 1.74130168 |
| 37 | MP0003866_abnormal_defecation | 1.72865936 |
| 38 | MP0002722_abnormal_immune_system | 1.72283060 |
| 39 | MP0004947_skin_inflammation | 1.72083600 |
| 40 | MP0002429_abnormal_blood_cell | 1.67861872 |
| 41 | MP0000703_abnormal_thymus_morphology | 1.60817899 |
| 42 | MP0008469_abnormal_protein_level | 1.52964668 |
| 43 | MP0003183_abnormal_peptide_metabolism | 1.52458333 |
| 44 | MP0001873_stomach_inflammation | 1.52183169 |
| 45 | MP0000465_gastrointestinal_hemorrhage | 1.47751480 |
| 46 | MP0005310_abnormal_salivary_gland | 1.45289273 |
| 47 | MP0004381_abnormal_hair_follicle | 1.42477079 |
| 48 | MP0009764_decreased_sensitivity_to | 1.31617623 |
| 49 | MP0000858_altered_metastatic_potential | 1.30946660 |
| 50 | MP0001545_abnormal_hematopoietic_system | 1.22638816 |
| 51 | MP0005397_hematopoietic_system_phenotyp | 1.22638816 |
| 52 | MP0005451_abnormal_body_composition | 1.21541693 |
| 53 | MP0002132_abnormal_respiratory_system | 1.19352039 |
| 54 | MP0004510_myositis | 1.17982541 |
| 55 | MP0002998_abnormal_bone_remodeling | 1.14853227 |
| 56 | MP0005075_abnormal_melanosome_morpholog | 1.13402455 |
| 57 | MP0000490_abnormal_crypts_of | 1.09342246 |
| 58 | MP0002166_altered_tumor_susceptibility | 1.06663722 |
| 59 | MP0001663_abnormal_digestive_system | 1.02218381 |
| 60 | MP0003075_altered_response_to | 1.01902684 |
| 61 | MP0002933_joint_inflammation | 1.01322116 |
| 62 | MP0009840_abnormal_foam_cell | 1.01213661 |
| 63 | MP0001851_eye_inflammation | 0.94408373 |
| 64 | MP0001853_heart_inflammation | 0.93763401 |
| 65 | MP0003828_pulmonary_edema | 0.93659530 |
| 66 | MP0005166_decreased_susceptibility_to | 0.91093356 |
| 67 | MP0004883_abnormal_blood_vessel | 0.90153799 |
| 68 | MP0004808_abnormal_hematopoietic_stem | 0.87765600 |
| 69 | MP0002277_abnormal_respiratory_mucosa | 0.86084847 |
| 70 | MP0000015_abnormal_ear_pigmentation | 0.85620554 |
| 71 | MP0001986_abnormal_taste_sensitivity | 0.85419018 |
| 72 | MP0000604_amyloidosis | 0.84589989 |
| 73 | MP0005390_skeleton_phenotype | 0.84347989 |
| 74 | MP0009763_increased_sensitivity_to | 0.84127763 |
| 75 | MP0003806_abnormal_nucleotide_metabolis | 0.83041109 |
| 76 | MP0002138_abnormal_hepatobiliary_system | 0.81475181 |
| 77 | MP0000343_altered_response_to | 0.78935667 |
| 78 | MP0003448_altered_tumor_morphology | 0.76192791 |
| 79 | MP0003690_abnormal_glial_cell | 0.75094180 |
| 80 | MP0003045_fibrosis | 0.72486861 |
| 81 | MP0005164_abnormal_response_to | 0.69977880 |
| 82 | MP0002019_abnormal_tumor_incidence | 0.66677757 |
| 83 | MP0003795_abnormal_bone_structure | 0.66080751 |
| 84 | MP0002006_tumorigenesis | 0.64699921 |
| 85 | MP0000249_abnormal_blood_vessel | 0.64034269 |
| 86 | MP0009765_abnormal_xenobiotic_induced | 0.63534378 |
| 87 | MP0008874_decreased_physiological_sensi | 0.62392393 |
| 88 | MP0005381_digestive/alimentary_phenotyp | 0.59232343 |
| 89 | MP0008004_abnormal_stomach_pH | 0.55649550 |
| 90 | MP0000609_abnormal_liver_physiology | 0.55619388 |
| 91 | MP0004858_abnormal_nervous_system | 0.54176222 |
| 92 | MP0005083_abnormal_biliary_tract | 0.54022470 |
| 93 | MP0002653_abnormal_ependyma_morphology | 0.53702881 |
| 94 | MP0003091_abnormal_cell_migration | 0.53191390 |
| 95 | MP0005076_abnormal_cell_differentiation | 0.52905028 |
| 96 | MP0000371_diluted_coat_color | 0.50931740 |
| 97 | MP0002693_abnormal_pancreas_physiology | 0.49223615 |
| 98 | MP0005319_abnormal_enzyme/_coenzyme | 0.49107835 |
| 99 | MP0003878_abnormal_ear_physiology | 0.46458165 |
| 100 | MP0005377_hearing/vestibular/ear_phenot | 0.46458165 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Eczematoid dermatitis (HP:0000976) | 6.23340879 |
| 2 | Recurrent abscess formation (HP:0002722) | 5.38848183 |
| 3 | Recurrent bacterial skin infections (HP:0005406) | 5.24879972 |
| 4 | Myositis (HP:0100614) | 5.08622713 |
| 5 | Abnormality of macrophages (HP:0004311) | 4.90126579 |
| 6 | Orchitis (HP:0100796) | 4.61583432 |
| 7 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.47997412 |
| 8 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 4.47357238 |
| 9 | Meningitis (HP:0001287) | 4.37395949 |
| 10 | Recurrent fungal infections (HP:0002841) | 4.36574924 |
| 11 | Mediastinal lymphadenopathy (HP:0100721) | 4.30885628 |
| 12 | Stomatitis (HP:0010280) | 4.27637424 |
| 13 | Retrobulbar optic neuritis (HP:0100654) | 4.26411002 |
| 14 | Optic neuritis (HP:0100653) | 4.26411002 |
| 15 | Recurrent gram-negative bacterial infections (HP:0005420) | 4.02658788 |
| 16 | Chronic obstructive pulmonary disease (HP:0006510) | 3.94900887 |
| 17 | Obstructive lung disease (HP:0006536) | 3.94900887 |
| 18 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.92939212 |
| 19 | Recurrent cutaneous fungal infections (HP:0011370) | 3.92939212 |
| 20 | Panhypogammaglobulinemia (HP:0003139) | 3.84468646 |
| 21 | Increased IgE level (HP:0003212) | 3.83393852 |
| 22 | Recurrent skin infections (HP:0001581) | 3.81036793 |
| 23 | Gastrointestinal infarctions (HP:0005244) | 3.73525829 |
| 24 | Encephalitis (HP:0002383) | 3.73161612 |
| 25 | Vasculitis (HP:0002633) | 3.65473331 |
| 26 | Cellulitis (HP:0100658) | 3.58468254 |
| 27 | Agammaglobulinemia (HP:0004432) | 3.54483791 |
| 28 | Recurrent viral infections (HP:0004429) | 3.43856170 |
| 29 | Colitis (HP:0002583) | 3.33147381 |
| 30 | Inflammation of the large intestine (HP:0002037) | 3.31836693 |
| 31 | Gastrointestinal inflammation (HP:0004386) | 3.31601970 |
| 32 | Spontaneous hematomas (HP:0007420) | 3.27821012 |
| 33 | Gingivitis (HP:0000230) | 3.19176141 |
| 34 | Pustule (HP:0200039) | 3.11587545 |
| 35 | Pulmonary infiltrates (HP:0002113) | 3.10789002 |
| 36 | Urticaria (HP:0001025) | 3.08014080 |
| 37 | Chest pain (HP:0100749) | 3.06983831 |
| 38 | Keratoconjunctivitis sicca (HP:0001097) | 3.04290755 |
| 39 | Gastrointestinal stroma tumor (HP:0100723) | 3.01106468 |
| 40 | Lymphopenia (HP:0001888) | 2.97520342 |
| 41 | Increased IgM level (HP:0003496) | 2.93266440 |
| 42 | Hemoptysis (HP:0002105) | 2.92549500 |
| 43 | Prolonged bleeding time (HP:0003010) | 2.91242603 |
| 44 | Abnormality of T cells (HP:0002843) | 2.89657501 |
| 45 | T lymphocytopenia (HP:0005403) | 2.89329531 |
| 46 | Keratoconjunctivitis (HP:0001096) | 2.85800741 |
| 47 | Hypochromic anemia (HP:0001931) | 2.80075102 |
| 48 | Granulocytopenia (HP:0001913) | 2.78532547 |
| 49 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.78435073 |
| 50 | Abnormality of T cell number (HP:0011839) | 2.76030845 |
| 51 | Abnormality of T cell physiology (HP:0011840) | 2.75387051 |
| 52 | Petechiae (HP:0000967) | 2.64725867 |
| 53 | Osteomyelitis (HP:0002754) | 2.62725411 |
| 54 | Epistaxis (HP:0000421) | 2.60875546 |
| 55 | IgM deficiency (HP:0002850) | 2.59881945 |
| 56 | Leukocytosis (HP:0001974) | 2.59739295 |
| 57 | Hypergammaglobulinemia (HP:0010702) | 2.50550691 |
| 58 | Increased cerebral lipofuscin (HP:0011813) | 2.49984480 |
| 59 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.46790722 |
| 60 | Abnormality of glycolipid metabolism (HP:0010969) | 2.46790722 |
| 61 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.46790722 |
| 62 | Sepsis (HP:0100806) | 2.45453685 |
| 63 | Systemic lupus erythematosus (HP:0002725) | 2.42862168 |
| 64 | Recurrent bronchitis (HP:0002837) | 2.41353381 |
| 65 | Abnormality of the pleura (HP:0002103) | 2.41028566 |
| 66 | Purpura (HP:0000979) | 2.40415681 |
| 67 | Hypochromic microcytic anemia (HP:0004840) | 2.38123476 |
| 68 | Recurrent sinusitis (HP:0011108) | 2.36954260 |
| 69 | Arterial thrombosis (HP:0004420) | 2.35243188 |
| 70 | Pulmonary embolism (HP:0002204) | 2.34812731 |
| 71 | Gingival bleeding (HP:0000225) | 2.34030289 |
| 72 | Dysostosis multiplex (HP:0000943) | 2.33533717 |
| 73 | Loss of speech (HP:0002371) | 2.31271012 |
| 74 | Anorexia (HP:0002039) | 2.29640129 |
| 75 | Restrictive lung disease (HP:0002091) | 2.27128095 |
| 76 | Recurrent pneumonia (HP:0006532) | 2.25251102 |
| 77 | Episodic fever (HP:0001954) | 2.24114746 |
| 78 | Emphysema (HP:0002097) | 2.23972486 |
| 79 | Eosinophilia (HP:0001880) | 2.23161220 |
| 80 | Recurrent lower respiratory tract infections (HP:0002783) | 2.22737288 |
| 81 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.22224457 |
| 82 | Papilloma (HP:0012740) | 2.21453995 |
| 83 | Verrucae (HP:0200043) | 2.21453995 |
| 84 | Hepatosplenomegaly (HP:0001433) | 2.18900082 |
| 85 | Abnormality of B cell number (HP:0010975) | 2.16746856 |
| 86 | Abnormality of the peritoneum (HP:0002585) | 2.16395677 |
| 87 | Chronic otitis media (HP:0000389) | 2.14009259 |
| 88 | Increased serum ferritin (HP:0003281) | 2.11529174 |
| 89 | Premature loss of primary teeth (HP:0006323) | 2.09533597 |
| 90 | Skin ulcer (HP:0200042) | 2.07658836 |
| 91 | Skin rash (HP:0000988) | 2.03278233 |
| 92 | Autoimmune thrombocytopenia (HP:0001973) | 2.03100623 |
| 93 | Viral hepatitis (HP:0006562) | 2.02939417 |
| 94 | Amyloidosis (HP:0011034) | 2.01114251 |
| 95 | Hypertensive crisis (HP:0100735) | 2.00735948 |
| 96 | IgG deficiency (HP:0004315) | 2.00105285 |
| 97 | Gangrene (HP:0100758) | 1.98809319 |
| 98 | Microcytic anemia (HP:0001935) | 1.98100808 |
| 99 | Arthralgia (HP:0002829) | 1.96599710 |
| 100 | Abnormality of iron homeostasis (HP:0011031) | 1.96540364 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K1 | 4.55844793 |
| 2 | ERN1 | 4.09876194 |
| 3 | RIPK4 | 4.04999091 |
| 4 | TYK2 | 2.89399905 |
| 5 | BLK | 2.85629489 |
| 6 | IRAK4 | 2.80549750 |
| 7 | MAP2K3 | 2.52138946 |
| 8 | PRPF4B | 2.45176047 |
| 9 | TNK2 | 2.32423043 |
| 10 | GRK6 | 2.17100774 |
| 11 | CSK | 2.13920184 |
| 12 | FES | 2.11773678 |
| 13 | ZAP70 | 1.99421681 |
| 14 | BTK | 1.91440025 |
| 15 | TRIB3 | 1.91365933 |
| 16 | EPHB1 | 1.86653077 |
| 17 | JAK3 | 1.84692999 |
| 18 | TBK1 | 1.84324064 |
| 19 | TXK | 1.80654967 |
| 20 | SYK | 1.79759370 |
| 21 | MAP3K14 | 1.76476857 |
| 22 | MAP3K11 | 1.75974651 |
| 23 | IKBKE | 1.70300404 |
| 24 | KIT | 1.61288518 |
| 25 | SIK3 | 1.58306404 |
| 26 | HCK | 1.56710441 |
| 27 | CSF1R | 1.55994803 |
| 28 | MAP3K13 | 1.55947101 |
| 29 | SMG1 | 1.51077767 |
| 30 | TESK2 | 1.48469247 |
| 31 | SIK2 | 1.44815084 |
| 32 | TAOK1 | 1.40412841 |
| 33 | LYN | 1.37836429 |
| 34 | JAK1 | 1.35078308 |
| 35 | MAP3K3 | 1.33488645 |
| 36 | FGR | 1.33471499 |
| 37 | LCK | 1.23848221 |
| 38 | ITK | 1.19324647 |
| 39 | FGFR4 | 1.18882800 |
| 40 | MARK3 | 1.18339200 |
| 41 | TAOK3 | 1.11943907 |
| 42 | JAK2 | 1.08145968 |
| 43 | SIK1 | 1.07718321 |
| 44 | IKBKB | 1.05421287 |
| 45 | PRKD2 | 1.04252084 |
| 46 | CDC42BPA | 1.00192672 |
| 47 | MAP3K1 | 0.92352786 |
| 48 | TAOK2 | 0.91346135 |
| 49 | MARK2 | 0.90085479 |
| 50 | PDK1 | 0.87530379 |
| 51 | MATK | 0.82735933 |
| 52 | TEC | 0.82044141 |
| 53 | PTK6 | 0.77632236 |
| 54 | CDK19 | 0.75879173 |
| 55 | STK10 | 0.75333121 |
| 56 | PDPK1 | 0.75091999 |
| 57 | MAP3K10 | 0.74890855 |
| 58 | HIPK2 | 0.74739055 |
| 59 | MAPK12 | 0.72578469 |
| 60 | MAP3K7 | 0.72293946 |
| 61 | MAP2K6 | 0.68085601 |
| 62 | MAPK11 | 0.66686293 |
| 63 | PRKCQ | 0.66661440 |
| 64 | IRAK1 | 0.63577264 |
| 65 | LRRK2 | 0.62841337 |
| 66 | EPHA3 | 0.61116171 |
| 67 | YES1 | 0.59862034 |
| 68 | FYN | 0.56254116 |
| 69 | PKN2 | 0.53477519 |
| 70 | MAPK7 | 0.53464772 |
| 71 | KSR2 | 0.53303171 |
| 72 | CAMKK1 | 0.53151192 |
| 73 | KDR | 0.53000783 |
| 74 | CDK4 | 0.52941415 |
| 75 | TGFBR2 | 0.51634259 |
| 76 | FGFR3 | 0.49541226 |
| 77 | RPS6KL1 | 0.48116045 |
| 78 | RPS6KC1 | 0.48116045 |
| 79 | DYRK1B | 0.47776791 |
| 80 | MAP2K2 | 0.47316037 |
| 81 | IRAK3 | 0.46695357 |
| 82 | MAPKAPK2 | 0.44398315 |
| 83 | IRAK2 | 0.42824567 |
| 84 | RPS6KA6 | 0.40996555 |
| 85 | BMPR2 | 0.38245320 |
| 86 | PTK2B | 0.38052868 |
| 87 | PIM1 | 0.37407034 |
| 88 | PRKCH | 0.36638131 |
| 89 | STK11 | 0.35063163 |
| 90 | MAP3K8 | 0.33195073 |
| 91 | BMX | 0.32569371 |
| 92 | NLK | 0.31217099 |
| 93 | RET | 0.30384583 |
| 94 | MAP3K6 | 0.29056648 |
| 95 | RPS6KA2 | 0.28596678 |
| 96 | ICK | 0.27542584 |
| 97 | MAPK4 | 0.27413932 |
| 98 | PRKD1 | 0.26801684 |
| 99 | CHUK | 0.26521664 |
| 100 | MAPK3 | 0.22266802 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.22010926 |
| 2 | Allograft rejection_Homo sapiens_hsa05330 | 3.13083275 |
| 3 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.99544310 |
| 4 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.90628667 |
| 5 | Leishmaniasis_Homo sapiens_hsa05140 | 2.82127789 |
| 6 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.80023955 |
| 7 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.65637711 |
| 8 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.37262508 |
| 9 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.32285575 |
| 10 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.23714444 |
| 11 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.16921667 |
| 12 | Asthma_Homo sapiens_hsa05310 | 2.15038271 |
| 13 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.12097643 |
| 14 | Other glycan degradation_Homo sapiens_hsa00511 | 2.06636764 |
| 15 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.05868808 |
| 16 | Tuberculosis_Homo sapiens_hsa05152 | 1.99016105 |
| 17 | Viral myocarditis_Homo sapiens_hsa05416 | 1.92939333 |
| 18 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.91838290 |
| 19 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.87676260 |
| 20 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.86094875 |
| 21 | Measles_Homo sapiens_hsa05162 | 1.78841128 |
| 22 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.77883548 |
| 23 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.69815893 |
| 24 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.66925742 |
| 25 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.64356822 |
| 26 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.62308714 |
| 27 | Influenza A_Homo sapiens_hsa05164 | 1.61258005 |
| 28 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.60712553 |
| 29 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.49840126 |
| 30 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.47647235 |
| 31 | Malaria_Homo sapiens_hsa05144 | 1.45775723 |
| 32 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.45759212 |
| 33 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.25653738 |
| 34 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.23225996 |
| 35 | Phagosome_Homo sapiens_hsa04145 | 1.22812087 |
| 36 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.17710079 |
| 37 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.16894890 |
| 38 | Hepatitis B_Homo sapiens_hsa05161 | 1.15752499 |
| 39 | Hepatitis C_Homo sapiens_hsa05160 | 1.14800935 |
| 40 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.14403845 |
| 41 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.13919731 |
| 42 | Legionellosis_Homo sapiens_hsa05134 | 1.06169856 |
| 43 | Pertussis_Homo sapiens_hsa05133 | 1.05334041 |
| 44 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.03202667 |
| 45 | Lysosome_Homo sapiens_hsa04142 | 1.01378342 |
| 46 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.00143410 |
| 47 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.99951071 |
| 48 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.97713716 |
| 49 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.95754891 |
| 50 | Platelet activation_Homo sapiens_hsa04611 | 0.94905589 |
| 51 | Shigellosis_Homo sapiens_hsa05131 | 0.94380456 |
| 52 | Apoptosis_Homo sapiens_hsa04210 | 0.94224640 |
| 53 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.94192844 |
| 54 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.89875739 |
| 55 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.86421529 |
| 56 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.86153299 |
| 57 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.84480309 |
| 58 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.84387927 |
| 59 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.77405523 |
| 60 | Salmonella infection_Homo sapiens_hsa05132 | 0.76838920 |
| 61 | HTLV-I infection_Homo sapiens_hsa05166 | 0.73151232 |
| 62 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.68233013 |
| 63 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.68117182 |
| 64 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.67340693 |
| 65 | Endocytosis_Homo sapiens_hsa04144 | 0.66866557 |
| 66 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.66286883 |
| 67 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.60041025 |
| 68 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.58936164 |
| 69 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.58680232 |
| 70 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.57200678 |
| 71 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.55603387 |
| 72 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.53983585 |
| 73 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.53573853 |
| 74 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.52537081 |
| 75 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.47170831 |
| 76 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.44130402 |
| 77 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.43220549 |
| 78 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.41829350 |
| 79 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.40505016 |
| 80 | Insulin resistance_Homo sapiens_hsa04931 | 0.40255765 |
| 81 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.39009519 |
| 82 | Colorectal cancer_Homo sapiens_hsa05210 | 0.37646112 |
| 83 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.37436450 |
| 84 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.36642362 |
| 85 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.34267572 |
| 86 | Endometrial cancer_Homo sapiens_hsa05213 | 0.34254094 |
| 87 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.33915749 |
| 88 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.32313086 |
| 89 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.31925376 |
| 90 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.31170925 |
| 91 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.30649137 |
| 92 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.28819390 |
| 93 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.28614346 |
| 94 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.28609741 |
| 95 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.27021977 |
| 96 | Bladder cancer_Homo sapiens_hsa05219 | 0.26466271 |
| 97 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.26180755 |
| 98 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.25115824 |
| 99 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.24439851 |
| 100 | Prostate cancer_Homo sapiens_hsa05215 | 0.24178103 |

