

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | neutrophil activation involved in immune response (GO:0002283) | 6.28737175 |
| 2 | negative regulation of cell killing (GO:0031342) | 5.64629240 |
| 3 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.64629240 |
| 4 | response to peptidoglycan (GO:0032494) | 5.61160463 |
| 5 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.60690029 |
| 6 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.59726337 |
| 7 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 5.57654876 |
| 8 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 5.57654876 |
| 9 | modulation by symbiont of host immune response (GO:0052553) | 5.57654876 |
| 10 | positive regulation by symbiont of host defense response (GO:0052509) | 5.57654876 |
| 11 | modulation by symbiont of host defense response (GO:0052031) | 5.57654876 |
| 12 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 5.57654876 |
| 13 | detection of other organism (GO:0098543) | 5.43914055 |
| 14 | detection of bacterium (GO:0016045) | 5.25425506 |
| 15 | antigen processing and presentation of endogenous antigen (GO:0019883) | 5.15975858 |
| 16 | macrophage activation involved in immune response (GO:0002281) | 4.85564379 |
| 17 | leukocyte aggregation (GO:0070486) | 4.82926413 |
| 18 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.79372662 |
| 19 | immunoglobulin mediated immune response (GO:0016064) | 4.70788774 |
| 20 | negative regulation of interleukin-12 production (GO:0032695) | 4.52820575 |
| 21 | detection of external biotic stimulus (GO:0098581) | 4.49103702 |
| 22 | neutrophil activation (GO:0042119) | 4.45933992 |
| 23 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.45615166 |
| 24 | cellular extravasation (GO:0045123) | 4.43557961 |
| 25 | leukocyte migration involved in inflammatory response (GO:0002523) | 4.37848978 |
| 26 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.29945605 |
| 27 | regulation of mast cell degranulation (GO:0043304) | 4.26213301 |
| 28 | respiratory burst (GO:0045730) | 4.20785121 |
| 29 | granulocyte activation (GO:0036230) | 4.12836186 |
| 30 | detection of molecule of bacterial origin (GO:0032490) | 4.12827898 |
| 31 | positive regulation of mast cell activation (GO:0033005) | 4.11220655 |
| 32 | regulation of interferon-beta biosynthetic process (GO:0045357) | 4.07736619 |
| 33 | detection of biotic stimulus (GO:0009595) | 4.03844710 |
| 34 | response to host immune response (GO:0052572) | 4.00817097 |
| 35 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 4.00817097 |
| 36 | regulation of mast cell activation involved in immune response (GO:0033006) | 4.00397408 |
| 37 | microglial cell activation (GO:0001774) | 3.98657442 |
| 38 | myeloid cell activation involved in immune response (GO:0002275) | 3.94845751 |
| 39 | regulation of gamma-delta T cell activation (GO:0046643) | 3.93475478 |
| 40 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 3.91789943 |
| 41 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 3.91647541 |
| 42 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.87511246 |
| 43 | regulation of mast cell activation (GO:0033003) | 3.79715024 |
| 44 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 3.75360819 |
| 45 | positive regulation of mast cell degranulation (GO:0043306) | 3.75360819 |
| 46 | macrophage activation (GO:0042116) | 3.73536465 |
| 47 | regulation of leukocyte degranulation (GO:0043300) | 3.73311632 |
| 48 | B cell mediated immunity (GO:0019724) | 3.68274953 |
| 49 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.67539223 |
| 50 | neutrophil mediated immunity (GO:0002446) | 3.66177678 |
| 51 | response to host (GO:0075136) | 3.65987746 |
| 52 | response to host defenses (GO:0052200) | 3.65987746 |
| 53 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.65987746 |
| 54 | response to muramyl dipeptide (GO:0032495) | 3.56071399 |
| 55 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.51152792 |
| 56 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.44275146 |
| 57 | negative regulation of T cell mediated immunity (GO:0002710) | 3.42645286 |
| 58 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.39684088 |
| 59 | leukocyte degranulation (GO:0043299) | 3.38380623 |
| 60 | regulation of tolerance induction (GO:0002643) | 3.35156269 |
| 61 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.34680794 |
| 62 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.33532906 |
| 63 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 3.33376586 |
| 64 | positive regulation of B cell differentiation (GO:0045579) | 3.31155564 |
| 65 | regulation of T cell tolerance induction (GO:0002664) | 3.30998651 |
| 66 | defense response to protozoan (GO:0042832) | 3.30681627 |
| 67 | cellular response to type I interferon (GO:0071357) | 3.25002825 |
| 68 | type I interferon signaling pathway (GO:0060337) | 3.25002825 |
| 69 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.24556336 |
| 70 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.24284375 |
| 71 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 3.23485093 |
| 72 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.23015836 |
| 73 | response to type I interferon (GO:0034340) | 3.21993839 |
| 74 | regulation of regulated secretory pathway (GO:1903305) | 3.20299331 |
| 75 | B cell receptor signaling pathway (GO:0050853) | 3.18756486 |
| 76 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 3.18673552 |
| 77 | regulation of B cell differentiation (GO:0045577) | 3.15546620 |
| 78 | myeloid leukocyte mediated immunity (GO:0002444) | 3.14464386 |
| 79 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.13293572 |
| 80 | response to interleukin-15 (GO:0070672) | 3.12342002 |
| 81 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 3.10429811 |
| 82 | regulation of antigen processing and presentation (GO:0002577) | 3.09774683 |
| 83 | negative regulation of cytokine production involved in immune response (GO:0002719) | 3.06133532 |
| 84 | germinal center formation (GO:0002467) | 3.06104898 |
| 85 | positive regulation of antigen processing and presentation (GO:0002579) | 3.05713033 |
| 86 | negative regulation of interleukin-6 production (GO:0032715) | 3.04829663 |
| 87 | response to protozoan (GO:0001562) | 2.99285947 |
| 88 | negative regulation of phagocytosis (GO:0050765) | 2.98560643 |
| 89 | myeloid leukocyte activation (GO:0002274) | 2.97113663 |
| 90 | positive regulation of interferon-alpha production (GO:0032727) | 2.95233432 |
| 91 | neutrophil chemotaxis (GO:0030593) | 2.92579570 |
| 92 | positive thymic T cell selection (GO:0045059) | 2.86452851 |
| 93 | positive regulation of cellular amide metabolic process (GO:0034250) | 2.86176682 |
| 94 | negative regulation of innate immune response (GO:0045824) | 2.85759167 |
| 95 | regulation of interferon-alpha production (GO:0032647) | 2.85394265 |
| 96 | neutrophil migration (GO:1990266) | 2.85159455 |
| 97 | positive regulation of leukocyte degranulation (GO:0043302) | 2.84988612 |
| 98 | positive regulation of type 2 immune response (GO:0002830) | 2.82785837 |
| 99 | positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557) | 2.82494536 |
| 100 | T-helper 1 type immune response (GO:0042088) | 2.81051972 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.89284003 |
| 2 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 5.05378346 |
| 3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 4.46010106 |
| 4 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.82422483 |
| 5 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.36575511 |
| 6 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.32169953 |
| 7 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.28435568 |
| 8 | VDR_21846776_ChIP-Seq_THP-1_Human | 3.05856075 |
| 9 | * SPI1_23547873_ChIP-Seq_NB4_Human | 2.94890812 |
| 10 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.93459516 |
| 11 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.92391324 |
| 12 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.88459874 |
| 13 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.87983125 |
| 14 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.79190046 |
| 15 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.68810866 |
| 16 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.67413471 |
| 17 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.66279134 |
| 18 | SPI1_23127762_ChIP-Seq_K562_Human | 2.60111558 |
| 19 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.59377828 |
| 20 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.51640718 |
| 21 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.42847844 |
| 22 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.39402056 |
| 23 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 2.37120075 |
| 24 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.35281498 |
| 25 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.31954986 |
| 26 | MAF_26560356_Chip-Seq_TH1_Human | 2.28755605 |
| 27 | MYB_26560356_Chip-Seq_TH2_Human | 2.28141863 |
| 28 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 2.23609208 |
| 29 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.14171419 |
| 30 | MYC_22102868_ChIP-Seq_BL_Human | 2.14129222 |
| 31 | UTX_26944678_Chip-Seq_JUKART_Human | 2.10532583 |
| 32 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 2.06972521 |
| 33 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.98391611 |
| 34 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.98367193 |
| 35 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.91140037 |
| 36 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.90834264 |
| 37 | MYB_26560356_Chip-Seq_TH1_Human | 1.89352991 |
| 38 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.85286589 |
| 39 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.83705959 |
| 40 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.82077421 |
| 41 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.77945578 |
| 42 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.77838979 |
| 43 | MAF_26560356_Chip-Seq_TH2_Human | 1.71759454 |
| 44 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.70252144 |
| 45 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.69852320 |
| 46 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.67030484 |
| 47 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.66370148 |
| 48 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.59484488 |
| 49 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.59326221 |
| 50 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.58749446 |
| 51 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.54761604 |
| 52 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.53814426 |
| 53 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.51841586 |
| 54 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.43562283 |
| 55 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.43068531 |
| 56 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.42014797 |
| 57 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.37162343 |
| 58 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.37038079 |
| 59 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.36751809 |
| 60 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.36528410 |
| 61 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.36346239 |
| 62 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.33227182 |
| 63 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.33153532 |
| 64 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.33135850 |
| 65 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.33055712 |
| 66 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.29497685 |
| 67 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.29364877 |
| 68 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.29194433 |
| 69 | GATA3_26560356_Chip-Seq_TH2_Human | 1.26925882 |
| 70 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.25945234 |
| 71 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.25842208 |
| 72 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.24896162 |
| 73 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.24546149 |
| 74 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.24435072 |
| 75 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.22187307 |
| 76 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.20737363 |
| 77 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.20582114 |
| 78 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.20378097 |
| 79 | GATA1_19941826_ChIP-Seq_K562_Human | 1.18781268 |
| 80 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.17187402 |
| 81 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.16678075 |
| 82 | GATA1_22025678_ChIP-Seq_K562_Human | 1.16560842 |
| 83 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.14875436 |
| 84 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.14333886 |
| 85 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.12500470 |
| 86 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.07074725 |
| 87 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.06946229 |
| 88 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.03168184 |
| 89 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.97540219 |
| 90 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.96120129 |
| 91 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.95405596 |
| 92 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.94153210 |
| 93 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.92762909 |
| 94 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.90674890 |
| 95 | GATA2_19941826_ChIP-Seq_K562_Human | 0.90597372 |
| 96 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.89867255 |
| 97 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.85775615 |
| 98 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.85223765 |
| 99 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 0.85047540 |
| 100 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 0.83880354 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003724_increased_susceptibility_to | 4.68096677 |
| 2 | MP0003436_decreased_susceptibility_to | 4.19714945 |
| 3 | MP0001835_abnormal_antigen_presentation | 4.05557896 |
| 4 | MP0003303_peritoneal_inflammation | 4.00916480 |
| 5 | MP0002419_abnormal_innate_immunity | 3.31963025 |
| 6 | MP0009785_altered_susceptibility_to | 3.01988942 |
| 7 | MP0005025_abnormal_response_to | 2.99898637 |
| 8 | MP0005671_abnormal_response_to | 2.95697493 |
| 9 | MP0005000_abnormal_immune_tolerance | 2.92414106 |
| 10 | MP0006082_CNS_inflammation | 2.90209691 |
| 11 | MP0001800_abnormal_humoral_immune | 2.83222658 |
| 12 | MP0001790_abnormal_immune_system | 2.81815823 |
| 13 | MP0005387_immune_system_phenotype | 2.81815823 |
| 14 | MP0000685_abnormal_immune_system | 2.65563532 |
| 15 | MP0002148_abnormal_hypersensitivity_rea | 2.63553285 |
| 16 | MP0002723_abnormal_immune_serum | 2.59687224 |
| 17 | MP0002452_abnormal_antigen_presenting | 2.57361183 |
| 18 | MP0002420_abnormal_adaptive_immunity | 2.53044692 |
| 19 | MP0001819_abnormal_immune_cell | 2.50619452 |
| 20 | MP0005464_abnormal_platelet_physiology | 2.35430681 |
| 21 | MP0003300_gastrointestinal_ulcer | 2.25634882 |
| 22 | MP0001533_abnormal_skeleton_physiology | 2.13093401 |
| 23 | MP0003191_abnormal_cellular_cholesterol | 2.07845948 |
| 24 | MP0003172_abnormal_lysosome_physiology | 2.04671027 |
| 25 | MP0009278_abnormal_bone_marrow | 2.03775448 |
| 26 | MP0002405_respiratory_system_inflammati | 2.02494353 |
| 27 | MP0008260_abnormal_autophagy | 1.91994591 |
| 28 | MP0003763_abnormal_thymus_physiology | 1.91975060 |
| 29 | MP0002398_abnormal_bone_marrow | 1.90428087 |
| 30 | MP0000465_gastrointestinal_hemorrhage | 1.88982344 |
| 31 | MP0000716_abnormal_immune_system | 1.87493497 |
| 32 | MP0001845_abnormal_inflammatory_respons | 1.83326969 |
| 33 | MP0010155_abnormal_intestine_physiology | 1.82198039 |
| 34 | MP0005058_abnormal_lysosome_morphology | 1.80592132 |
| 35 | MP0002132_abnormal_respiratory_system | 1.79106194 |
| 36 | MP0003828_pulmonary_edema | 1.78862718 |
| 37 | MP0004947_skin_inflammation | 1.65257063 |
| 38 | MP0005397_hematopoietic_system_phenotyp | 1.63441756 |
| 39 | MP0001545_abnormal_hematopoietic_system | 1.63441756 |
| 40 | MP0003075_altered_response_to | 1.62049761 |
| 41 | MP0009764_decreased_sensitivity_to | 1.60775433 |
| 42 | MP0000689_abnormal_spleen_morphology | 1.58636641 |
| 43 | MP0002722_abnormal_immune_system | 1.55975618 |
| 44 | MP0008469_abnormal_protein_level | 1.55064040 |
| 45 | MP0009333_abnormal_splenocyte_physiolog | 1.53465144 |
| 46 | MP0002429_abnormal_blood_cell | 1.50296623 |
| 47 | MP0003183_abnormal_peptide_metabolism | 1.48858833 |
| 48 | MP0002396_abnormal_hematopoietic_system | 1.44206597 |
| 49 | MP0003806_abnormal_nucleotide_metabolis | 1.43679713 |
| 50 | MP0003866_abnormal_defecation | 1.37023387 |
| 51 | MP0005310_abnormal_salivary_gland | 1.35435420 |
| 52 | MP0004510_myositis | 1.35432037 |
| 53 | MP0000858_altered_metastatic_potential | 1.27981253 |
| 54 | MP0002998_abnormal_bone_remodeling | 1.27409789 |
| 55 | MP0001851_eye_inflammation | 1.27061372 |
| 56 | MP0000703_abnormal_thymus_morphology | 1.25694229 |
| 57 | MP0005451_abnormal_body_composition | 1.22269464 |
| 58 | MP0005166_decreased_susceptibility_to | 1.18651053 |
| 59 | MP0004883_abnormal_blood_vessel | 1.18246426 |
| 60 | MP0008004_abnormal_stomach_pH | 1.15580098 |
| 61 | MP0002277_abnormal_respiratory_mucosa | 1.13736683 |
| 62 | MP0000343_altered_response_to | 1.11313530 |
| 63 | MP0003690_abnormal_glial_cell | 1.06903147 |
| 64 | MP0004381_abnormal_hair_follicle | 1.01926849 |
| 65 | MP0001853_heart_inflammation | 1.01743232 |
| 66 | MP0002166_altered_tumor_susceptibility | 1.01690264 |
| 67 | MP0001873_stomach_inflammation | 1.01520641 |
| 68 | MP0004808_abnormal_hematopoietic_stem | 0.95914962 |
| 69 | MP0005164_abnormal_response_to | 0.95017956 |
| 70 | MP0003656_abnormal_erythrocyte_physiolo | 0.93035991 |
| 71 | MP0003448_altered_tumor_morphology | 0.92569445 |
| 72 | MP0001663_abnormal_digestive_system | 0.92306119 |
| 73 | MP0005390_skeleton_phenotype | 0.90518970 |
| 74 | MP0009763_increased_sensitivity_to | 0.90127818 |
| 75 | MP0005075_abnormal_melanosome_morpholog | 0.89947431 |
| 76 | MP0000604_amyloidosis | 0.87445421 |
| 77 | MP0002138_abnormal_hepatobiliary_system | 0.86205269 |
| 78 | MP0000490_abnormal_crypts_of | 0.78044480 |
| 79 | MP0001986_abnormal_taste_sensitivity | 0.75635456 |
| 80 | MP0009765_abnormal_xenobiotic_induced | 0.72266305 |
| 81 | MP0000015_abnormal_ear_pigmentation | 0.68217935 |
| 82 | MP0003795_abnormal_bone_structure | 0.67755407 |
| 83 | MP0002006_tumorigenesis | 0.64645059 |
| 84 | MP0005319_abnormal_enzyme/_coenzyme | 0.60456810 |
| 85 | MP0009840_abnormal_foam_cell | 0.60046567 |
| 86 | MP0000249_abnormal_blood_vessel | 0.59188623 |
| 87 | MP0002933_joint_inflammation | 0.58341974 |
| 88 | MP0008874_decreased_physiological_sensi | 0.54637990 |
| 89 | MP0003045_fibrosis | 0.51892830 |
| 90 | MP0002009_preneoplasia | 0.51660860 |
| 91 | MP0002332_abnormal_exercise_endurance | 0.51591995 |
| 92 | MP0005535_abnormal_body_temperature | 0.49703459 |
| 93 | MP0005083_abnormal_biliary_tract | 0.49058653 |
| 94 | MP0005381_digestive/alimentary_phenotyp | 0.47895372 |
| 95 | MP0006054_spinal_hemorrhage | 0.47597420 |
| 96 | MP0002019_abnormal_tumor_incidence | 0.47225725 |
| 97 | MP0005084_abnormal_gallbladder_morpholo | 0.46843447 |
| 98 | MP0002693_abnormal_pancreas_physiology | 0.45347355 |
| 99 | MP0000920_abnormal_myelination | 0.43507583 |
| 100 | MP0003091_abnormal_cell_migration | 0.42715875 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Eczematoid dermatitis (HP:0000976) | 6.57200613 |
| 2 | Recurrent abscess formation (HP:0002722) | 6.26654387 |
| 3 | Recurrent bacterial skin infections (HP:0005406) | 6.21137529 |
| 4 | Abnormality of macrophages (HP:0004311) | 5.88733865 |
| 5 | Myositis (HP:0100614) | 5.63527572 |
| 6 | Stomatitis (HP:0010280) | 5.21651474 |
| 7 | Orchitis (HP:0100796) | 5.17753172 |
| 8 | Recurrent gram-negative bacterial infections (HP:0005420) | 5.08956075 |
| 9 | Optic neuritis (HP:0100653) | 4.90282852 |
| 10 | Retrobulbar optic neuritis (HP:0100654) | 4.90282852 |
| 11 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.76982640 |
| 12 | Obstructive lung disease (HP:0006536) | 4.40533364 |
| 13 | Chronic obstructive pulmonary disease (HP:0006510) | 4.40533364 |
| 14 | Mediastinal lymphadenopathy (HP:0100721) | 4.25155020 |
| 15 | Recurrent fungal infections (HP:0002841) | 4.24909829 |
| 16 | Recurrent skin infections (HP:0001581) | 4.16444295 |
| 17 | Meningitis (HP:0001287) | 4.03276907 |
| 18 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.86447033 |
| 19 | Recurrent cutaneous fungal infections (HP:0011370) | 3.78604079 |
| 20 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.78604079 |
| 21 | Gastrointestinal infarctions (HP:0005244) | 3.78485416 |
| 22 | Urticaria (HP:0001025) | 3.65212721 |
| 23 | Keratoconjunctivitis sicca (HP:0001097) | 3.57224684 |
| 24 | Prolonged bleeding time (HP:0003010) | 3.56084244 |
| 25 | Encephalitis (HP:0002383) | 3.55603002 |
| 26 | Gingivitis (HP:0000230) | 3.48148869 |
| 27 | Vasculitis (HP:0002633) | 3.38749277 |
| 28 | Spontaneous hematomas (HP:0007420) | 3.36416496 |
| 29 | Cellulitis (HP:0100658) | 3.31631785 |
| 30 | Increased IgE level (HP:0003212) | 3.29746351 |
| 31 | Keratoconjunctivitis (HP:0001096) | 3.29650044 |
| 32 | Episodic fever (HP:0001954) | 3.25149396 |
| 33 | Hypochromic microcytic anemia (HP:0004840) | 3.19520345 |
| 34 | Petechiae (HP:0000967) | 3.17199494 |
| 35 | Amyloidosis (HP:0011034) | 3.15497528 |
| 36 | Chest pain (HP:0100749) | 3.10119295 |
| 37 | Abnormality of glycolipid metabolism (HP:0010969) | 3.03520028 |
| 38 | Abnormality of liposaccharide metabolism (HP:0010968) | 3.03520028 |
| 39 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 3.03520028 |
| 40 | Hemoptysis (HP:0002105) | 3.02951001 |
| 41 | Pulmonary infiltrates (HP:0002113) | 3.02620200 |
| 42 | Gingival bleeding (HP:0000225) | 2.96513515 |
| 43 | Recurrent viral infections (HP:0004429) | 2.95681905 |
| 44 | Epistaxis (HP:0000421) | 2.95216185 |
| 45 | Hypochromic anemia (HP:0001931) | 2.85545015 |
| 46 | Leukocytosis (HP:0001974) | 2.82019610 |
| 47 | Increased cerebral lipofuscin (HP:0011813) | 2.81929317 |
| 48 | Inflammation of the large intestine (HP:0002037) | 2.74125034 |
| 49 | Arterial thrombosis (HP:0004420) | 2.73546251 |
| 50 | Increased IgM level (HP:0003496) | 2.65228841 |
| 51 | Gastrointestinal inflammation (HP:0004386) | 2.63385171 |
| 52 | Panhypogammaglobulinemia (HP:0003139) | 2.62470213 |
| 53 | Purpura (HP:0000979) | 2.61989786 |
| 54 | Anorexia (HP:0002039) | 2.60565168 |
| 55 | Loss of speech (HP:0002371) | 2.57445644 |
| 56 | Pulmonary embolism (HP:0002204) | 2.57398089 |
| 57 | Osteomyelitis (HP:0002754) | 2.55853067 |
| 58 | Pustule (HP:0200039) | 2.47856458 |
| 59 | T lymphocytopenia (HP:0005403) | 2.47347028 |
| 60 | Peritonitis (HP:0002586) | 2.45399552 |
| 61 | Abnormality of T cell number (HP:0011839) | 2.41221594 |
| 62 | Increased serum ferritin (HP:0003281) | 2.38720693 |
| 63 | Gangrene (HP:0100758) | 2.37941837 |
| 64 | Granulocytopenia (HP:0001913) | 2.37568543 |
| 65 | Abnormality of T cells (HP:0002843) | 2.36593686 |
| 66 | Hepatosplenomegaly (HP:0001433) | 2.35794060 |
| 67 | Colitis (HP:0002583) | 2.34880401 |
| 68 | Abnormality of the pleura (HP:0002103) | 2.31762899 |
| 69 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.30503413 |
| 70 | Sepsis (HP:0100806) | 2.28609407 |
| 71 | Hypergammaglobulinemia (HP:0010702) | 2.22297894 |
| 72 | Abnormality of T cell physiology (HP:0011840) | 2.18942092 |
| 73 | Microcytic anemia (HP:0001935) | 2.18214178 |
| 74 | Abnormality of iron homeostasis (HP:0011031) | 2.17321250 |
| 75 | Vertigo (HP:0002321) | 2.16734837 |
| 76 | Disinhibition (HP:0000734) | 2.16604323 |
| 77 | Dysostosis multiplex (HP:0000943) | 2.16070925 |
| 78 | Agammaglobulinemia (HP:0004432) | 2.15456706 |
| 79 | Polyneuropathy (HP:0001271) | 2.12018053 |
| 80 | Vacuolated lymphocytes (HP:0001922) | 2.11774372 |
| 81 | Systemic lupus erythematosus (HP:0002725) | 2.07713506 |
| 82 | Glomerulopathy (HP:0100820) | 2.07331566 |
| 83 | Autoimmune thrombocytopenia (HP:0001973) | 2.06266167 |
| 84 | Abnormality of the peritoneum (HP:0002585) | 2.06105565 |
| 85 | Skin ulcer (HP:0200042) | 2.05182507 |
| 86 | Premature loss of primary teeth (HP:0006323) | 2.04404402 |
| 87 | Lymphopenia (HP:0001888) | 2.04283941 |
| 88 | Abnormality of the endocardium (HP:0004306) | 2.01425806 |
| 89 | Abnormal platelet volume (HP:0011876) | 1.98169554 |
| 90 | Acne (HP:0001061) | 1.93978910 |
| 91 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 1.91553027 |
| 92 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.90062106 |
| 93 | Recurrent pneumonia (HP:0006532) | 1.88939449 |
| 94 | Skin rash (HP:0000988) | 1.88681557 |
| 95 | Acute hepatic failure (HP:0006554) | 1.86768137 |
| 96 | Chronic otitis media (HP:0000389) | 1.85717365 |
| 97 | Abnormality of the pericardium (HP:0001697) | 1.84804278 |
| 98 | Amaurosis fugax (HP:0100576) | 1.83585615 |
| 99 | Eosinophilia (HP:0001880) | 1.83123594 |
| 100 | Autoimmune hemolytic anemia (HP:0001890) | 1.82727857 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RIPK4 | 5.02092662 |
| 2 | MAP4K1 | 3.61659098 |
| 3 | BLK | 3.31672004 |
| 4 | MAP2K3 | 3.11840410 |
| 5 | IRAK4 | 3.11224367 |
| 6 | FES | 2.83049433 |
| 7 | TYK2 | 2.72682867 |
| 8 | ERN1 | 2.63559715 |
| 9 | CSK | 2.61565233 |
| 10 | TNK2 | 2.42329122 |
| 11 | PRPF4B | 2.25012809 |
| 12 | GRK6 | 2.24707684 |
| 13 | ZAP70 | 2.15081261 |
| 14 | TAOK1 | 1.95705288 |
| 15 | BTK | 1.92944444 |
| 16 | MAP3K3 | 1.87907108 |
| 17 | FGR | 1.87853237 |
| 18 | SYK | 1.86456549 |
| 19 | JAK3 | 1.78896563 |
| 20 | HCK | 1.77861904 |
| 21 | MAP3K11 | 1.74855558 |
| 22 | TBK1 | 1.69415454 |
| 23 | TXK | 1.68163587 |
| 24 | IKBKE | 1.67317842 |
| 25 | CSF1R | 1.66631151 |
| 26 | MAP3K14 | 1.64273045 |
| 27 | KIT | 1.61556284 |
| 28 | LYN | 1.51441823 |
| 29 | CDK19 | 1.49333517 |
| 30 | EPHB1 | 1.48183810 |
| 31 | JAK2 | 1.34145543 |
| 32 | MAP3K13 | 1.33363070 |
| 33 | MAP3K1 | 1.30180251 |
| 34 | TAOK3 | 1.28831350 |
| 35 | SIK3 | 1.24165476 |
| 36 | BMPR2 | 1.20117215 |
| 37 | TAOK2 | 1.18988502 |
| 38 | LCK | 1.18883251 |
| 39 | JAK1 | 1.16924099 |
| 40 | MATK | 1.16332028 |
| 41 | MARK3 | 1.11829718 |
| 42 | TEC | 1.10648114 |
| 43 | IKBKB | 1.10100568 |
| 44 | KSR2 | 1.04184714 |
| 45 | ITK | 1.01555921 |
| 46 | YES1 | 0.98987568 |
| 47 | TESK2 | 0.94023674 |
| 48 | PDK1 | 0.92285712 |
| 49 | IRAK2 | 0.89870570 |
| 50 | MARK2 | 0.88651456 |
| 51 | IRAK1 | 0.84406259 |
| 52 | STK10 | 0.82539448 |
| 53 | PRKD2 | 0.81974887 |
| 54 | PDPK1 | 0.81878341 |
| 55 | MAPK7 | 0.81194947 |
| 56 | MAP3K6 | 0.79876570 |
| 57 | GRK7 | 0.73003345 |
| 58 | IRAK3 | 0.72131765 |
| 59 | TGFBR2 | 0.67100234 |
| 60 | SIK2 | 0.65526990 |
| 61 | PTK6 | 0.65065996 |
| 62 | MAP3K5 | 0.64175398 |
| 63 | PIK3CG | 0.63987736 |
| 64 | FYN | 0.63156508 |
| 65 | NLK | 0.62288317 |
| 66 | LRRK2 | 0.56738227 |
| 67 | MAPK12 | 0.56355864 |
| 68 | MOS | 0.54296024 |
| 69 | RPS6KC1 | 0.52717952 |
| 70 | RPS6KL1 | 0.52717952 |
| 71 | MAP2K4 | 0.51235419 |
| 72 | DYRK1B | 0.51227239 |
| 73 | SGK3 | 0.50797856 |
| 74 | PIM1 | 0.49892849 |
| 75 | HIPK2 | 0.49541912 |
| 76 | PRKCQ | 0.48259316 |
| 77 | CDC42BPA | 0.47687290 |
| 78 | TRIB3 | 0.44790654 |
| 79 | RPS6KA6 | 0.44370637 |
| 80 | DAPK2 | 0.43961016 |
| 81 | PTK2B | 0.43924804 |
| 82 | MAP3K7 | 0.43763454 |
| 83 | STK11 | 0.43206532 |
| 84 | MAP2K6 | 0.38681912 |
| 85 | MAP3K2 | 0.38674501 |
| 86 | SGK2 | 0.36662996 |
| 87 | MAPKAPK2 | 0.35927658 |
| 88 | SMG1 | 0.35116795 |
| 89 | RAF1 | 0.33203404 |
| 90 | CDK4 | 0.33063482 |
| 91 | PRKCD | 0.32543746 |
| 92 | ABL1 | 0.30110965 |
| 93 | MAP2K2 | 0.30020419 |
| 94 | SIK1 | 0.28753552 |
| 95 | CDK6 | 0.27234439 |
| 96 | RET | 0.26047742 |
| 97 | BCKDK | 0.25773786 |
| 98 | MAPK4 | 0.25621460 |
| 99 | KSR1 | 0.24677037 |
| 100 | MAP3K8 | 0.24033699 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Leishmaniasis_Homo sapiens_hsa05140 | 3.31622009 |
| 2 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 3.15079474 |
| 3 | Osteoclast differentiation_Homo sapiens_hsa04380 | 3.00273995 |
| 4 | Allograft rejection_Homo sapiens_hsa05330 | 2.82925622 |
| 5 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.78668083 |
| 6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.58814951 |
| 7 | Asthma_Homo sapiens_hsa05310 | 2.33894314 |
| 8 | Tuberculosis_Homo sapiens_hsa05152 | 2.30083722 |
| 9 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.13645066 |
| 10 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.12593855 |
| 11 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.06392332 |
| 12 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.05823104 |
| 13 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.02854774 |
| 14 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 2.02691566 |
| 15 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.95900551 |
| 16 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.92212655 |
| 17 | Malaria_Homo sapiens_hsa05144 | 1.92165840 |
| 18 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.90171243 |
| 19 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.89878761 |
| 20 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.87241635 |
| 21 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.83441171 |
| 22 | Legionellosis_Homo sapiens_hsa05134 | 1.74321786 |
| 23 | Viral myocarditis_Homo sapiens_hsa05416 | 1.72218096 |
| 24 | Other glycan degradation_Homo sapiens_hsa00511 | 1.71275261 |
| 25 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.58669384 |
| 26 | Influenza A_Homo sapiens_hsa05164 | 1.57490492 |
| 27 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.56676019 |
| 28 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.54590312 |
| 29 | Measles_Homo sapiens_hsa05162 | 1.54477065 |
| 30 | Phagosome_Homo sapiens_hsa04145 | 1.53806166 |
| 31 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.52016861 |
| 32 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.50072668 |
| 33 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.46430567 |
| 34 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.44003376 |
| 35 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.36573732 |
| 36 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.36012025 |
| 37 | Pertussis_Homo sapiens_hsa05133 | 1.31810043 |
| 38 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.30082103 |
| 39 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.24224089 |
| 40 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.22224251 |
| 41 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.19970307 |
| 42 | Salmonella infection_Homo sapiens_hsa05132 | 1.17236061 |
| 43 | Platelet activation_Homo sapiens_hsa04611 | 1.17106201 |
| 44 | Lysosome_Homo sapiens_hsa04142 | 1.15714412 |
| 45 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.09780778 |
| 46 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.07636469 |
| 47 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.05935778 |
| 48 | Shigellosis_Homo sapiens_hsa05131 | 1.05487133 |
| 49 | Hepatitis B_Homo sapiens_hsa05161 | 1.02202466 |
| 50 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.92239067 |
| 51 | Hepatitis C_Homo sapiens_hsa05160 | 0.91695734 |
| 52 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.90386401 |
| 53 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.88785460 |
| 54 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.87787679 |
| 55 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.82333125 |
| 56 | Apoptosis_Homo sapiens_hsa04210 | 0.79091318 |
| 57 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.79048032 |
| 58 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.74096404 |
| 59 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.71278073 |
| 60 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.70527269 |
| 61 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.69687209 |
| 62 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.66366512 |
| 63 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.66203948 |
| 64 | Amoebiasis_Homo sapiens_hsa05146 | 0.65555573 |
| 65 | Endocytosis_Homo sapiens_hsa04144 | 0.65024119 |
| 66 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.63986813 |
| 67 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.62789035 |
| 68 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.60995473 |
| 69 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.60883194 |
| 70 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.55517943 |
| 71 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.54263530 |
| 72 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.52761283 |
| 73 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.52725484 |
| 74 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.51185302 |
| 75 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.50358130 |
| 76 | HTLV-I infection_Homo sapiens_hsa05166 | 0.50209562 |
| 77 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.50198216 |
| 78 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.47829401 |
| 79 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.47274306 |
| 80 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.45512835 |
| 81 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.45132569 |
| 82 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.43343221 |
| 83 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.42162774 |
| 84 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.40654162 |
| 85 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.40285842 |
| 86 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.37994416 |
| 87 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.37905991 |
| 88 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.37609809 |
| 89 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.35646431 |
| 90 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.34943841 |
| 91 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.34808814 |
| 92 | Insulin resistance_Homo sapiens_hsa04931 | 0.34790076 |
| 93 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.34754160 |
| 94 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.34513498 |
| 95 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.33388008 |
| 96 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.28554297 |
| 97 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.27245927 |
| 98 | Endometrial cancer_Homo sapiens_hsa05213 | 0.27224089 |
| 99 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.26835503 |
| 100 | Colorectal cancer_Homo sapiens_hsa05210 | 0.26112454 |

