C1ORF159

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mannose metabolic process (GO:0006013)4.15301273
2negative regulation of erythrocyte differentiation (GO:0045647)4.04963237
3intracellular estrogen receptor signaling pathway (GO:0030520)4.01567749
4negative regulation of cell size (GO:0045792)3.95066495
5pyrimidine nucleoside salvage (GO:0043097)3.85252616
6pyrimidine-containing compound salvage (GO:0008655)3.85252616
7snRNA metabolic process (GO:0016073)3.81239961
8NIK/NF-kappaB signaling (GO:0038061)3.80324697
9GDP-mannose metabolic process (GO:0019673)3.73595362
10protein retention in ER lumen (GO:0006621)3.67821053
11histone H4 deacetylation (GO:0070933)3.62341223
12negative regulation of DNA-templated transcription, elongation (GO:0032785)3.59437649
13snRNA processing (GO:0016180)3.56423342
14regulation of NFAT protein import into nucleus (GO:0051532)3.55337891
15negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)3.54932710
16RNA localization (GO:0006403)3.50656168
17regulation of mammary gland epithelial cell proliferation (GO:0033599)3.49894158
18positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.49554168
19protein insertion into membrane (GO:0051205)3.47932168
20peptidyl-arginine omega-N-methylation (GO:0035247)3.45618302
21positive regulation of histone deacetylation (GO:0031065)3.43206025
22histone H3 deacetylation (GO:0070932)3.43067204
23activation of MAPKKK activity (GO:0000185)3.36606267
24semaphorin-plexin signaling pathway (GO:0071526)3.34436523
25regulation of chromatin binding (GO:0035561)3.33493766
26protein-DNA complex disassembly (GO:0032986)3.30873601
27nucleosome disassembly (GO:0006337)3.30873601
28cell-cell junction maintenance (GO:0045217)3.29231528
29establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.26836403
30mitochondrion transport along microtubule (GO:0047497)3.26836403
31establishment of mitochondrion localization (GO:0051654)3.26105202
32maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.24974580
33spliceosomal tri-snRNP complex assembly (GO:0000244)3.19447905
34regulation of ARF GTPase activity (GO:0032312)3.17631004
35modulation by virus of host process (GO:0019054)3.12979200
36cellular response to virus (GO:0098586)3.12255037
37apoptotic process involved in morphogenesis (GO:0060561)3.10668808
38glucose 6-phosphate metabolic process (GO:0051156)3.09251445
39proline biosynthetic process (GO:0006561)3.08936192
40signal complex assembly (GO:0007172)3.05530790
41retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.04642848
42Golgi transport vesicle coating (GO:0048200)3.03461691
43COPI coating of Golgi vesicle (GO:0048205)3.03461691
44positive regulation of Cdc42 GTPase activity (GO:0043089)3.00836342
45positive regulation of protein deacetylation (GO:0090312)3.00529130
46regulation of type I interferon-mediated signaling pathway (GO:0060338)2.99609701
47retinoic acid receptor signaling pathway (GO:0048384)2.95144753
48pentose metabolic process (GO:0019321)2.94482243
49response to muramyl dipeptide (GO:0032495)2.93015329
50modulation by symbiont of host cellular process (GO:0044068)2.91738116
51histone H3-K4 methylation (GO:0051568)2.89284182
52metallo-sulfur cluster assembly (GO:0031163)2.89246240
53iron-sulfur cluster assembly (GO:0016226)2.89246240
54nuclear envelope reassembly (GO:0031468)2.83554904
55mitotic nuclear envelope reassembly (GO:0007084)2.83554904
56UV protection (GO:0009650)2.82792626
57regulation of mitochondrial translation (GO:0070129)2.80700882
58regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315)2.79023811
59nucleotide salvage (GO:0043173)2.76750796
60activation of Rac GTPase activity (GO:0032863)2.74280645
61negative regulation of viral release from host cell (GO:1902187)2.70029595
62peptidyl-arginine N-methylation (GO:0035246)2.67390596
63peptidyl-arginine methylation (GO:0018216)2.67390596
64protein maturation by protein folding (GO:0022417)2.65684152
65negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.65660891
66regulation of hydrogen peroxide metabolic process (GO:0010310)2.65249744
67Arp2/3 complex-mediated actin nucleation (GO:0034314)2.63882226
68negative regulation of gene expression, epigenetic (GO:0045814)2.62204835
69regulation of histone H3-K27 methylation (GO:0061085)2.59347875
70negative regulation of myeloid cell apoptotic process (GO:0033033)2.59129447
71regulation of monocyte differentiation (GO:0045655)2.57272438
72DNA packaging (GO:0006323)2.56777247
73chromatin silencing (GO:0006342)2.56770056
74chromosome condensation (GO:0030261)2.56434799
75planar cell polarity pathway involved in neural tube closure (GO:0090179)2.56187478
76negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.55919221
77retrograde transport, endosome to Golgi (GO:0042147)2.55541216
78negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)2.55504146
79microtubule severing (GO:0051013)2.54095479
80phosphatidylglycerol biosynthetic process (GO:0006655)2.48776957
81histone deacetylation (GO:0016575)2.48667681
82deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.47988420
83ncRNA 3-end processing (GO:0043628)2.47617231
84regulation of translational fidelity (GO:0006450)2.46849003
85maintenance of protein localization in organelle (GO:0072595)2.46283527
86positive regulation of receptor biosynthetic process (GO:0010870)2.46176462
87positive regulation of histone acetylation (GO:0035066)2.45980223
88negative regulation of interleukin-2 production (GO:0032703)2.45525149
89positive regulation of protein kinase C signaling (GO:0090037)2.45266634
90pentose-phosphate shunt (GO:0006098)2.43043843
91regulation of histone deacetylation (GO:0031063)2.42660257
92poly(A)+ mRNA export from nucleus (GO:0016973)2.41564944
93positive regulation of peptidyl-lysine acetylation (GO:2000758)2.39397153
94positive regulation of protein acetylation (GO:1901985)2.39397153
95histone arginine methylation (GO:0034969)2.39214795
96virion assembly (GO:0019068)2.37899723
97histone H3-K4 trimethylation (GO:0080182)2.36174012
98regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.32917593
99glucose catabolic process (GO:0006007)2.32710936
100protein kinase C signaling (GO:0070528)2.31822179

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.56691834
2VDR_21846776_ChIP-Seq_THP-1_Human2.95388721
3* LXR_22292898_ChIP-Seq_THP-1_Human2.92705694
4MYC_22102868_ChIP-Seq_BL_Human2.51071591
5TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.48011289
6ELK3_25401928_ChIP-Seq_HUVEC_Human2.31926660
7* KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.21066518
8THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.19557186
9P68_20966046_ChIP-Seq_HELA_Human2.18786501
10KDM2B_26808549_Chip-Seq_SUP-B15_Human2.09998027
11EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.01313731
12TET1_21451524_ChIP-Seq_MESCs_Mouse1.97652030
13RACK7_27058665_Chip-Seq_MCF-7_Human1.96888281
14* KDM2B_26808549_Chip-Seq_DND41_Human1.93376987
15CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.91997660
16HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.89852916
17RARG_19884340_ChIP-ChIP_MEFs_Mouse1.88095376
18ELF1_20517297_ChIP-Seq_JURKAT_Human1.84549955
19DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.82395391
20* SA1_27219007_Chip-Seq_ERYTHROID_Human1.81976946
21SMC4_20622854_ChIP-Seq_HELA_Human1.80022534
22EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.78473671
23NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.76420814
24BCL6_27268052_Chip-Seq_Bcells_Human1.74702677
25* BCOR_27268052_Chip-Seq_Bcells_Human1.71412468
26CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.71313668
27TCF7_22412390_ChIP-Seq_EML_Mouse1.67845457
28MAF_26560356_Chip-Seq_TH2_Human1.64357374
29MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.63502382
30SRY_22984422_ChIP-ChIP_TESTIS_Rat1.63065662
31MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.61439175
32* CTCF_27219007_Chip-Seq_ERYTHROID_Human1.61325232
33* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.58316348
34* PHF8_20622854_ChIP-Seq_HELA_Human1.51280263
35* KDM2B_26808549_Chip-Seq_K562_Human1.50136842
36SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.48480529
37STAT6_21828071_ChIP-Seq_BEAS2B_Human1.48182085
38E2F7_22180533_ChIP-Seq_HELA_Human1.46496172
39* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.45759022
40* MAF_26560356_Chip-Seq_TH1_Human1.45703253
41* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.44965810
42ERG_21242973_ChIP-ChIP_JURKAT_Human1.44356423
43XRN2_22483619_ChIP-Seq_HELA_Human1.43892462
44JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.42922830
45CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.41031678
46NCOR1_26117541_ChIP-Seq_K562_Human1.40609827
47KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.39142752
48E2F1_20622854_ChIP-Seq_HELA_Human1.38610887
49ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.38603327
50* CREB1_26743006_Chip-Seq_LNCaP_Human1.36609367
51ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.36204286
52* CTCF_27219007_Chip-Seq_Bcells_Human1.35256455
53UTX_26944678_Chip-Seq_JUKART_Human1.34466565
54PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.32297657
55MYC_18358816_ChIP-ChIP_MESCs_Mouse1.31810970
56SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.30896676
57CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.30499562
58* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.29467803
59* KDM2B_26808549_Chip-Seq_JURKAT_Human1.29027820
60THAP11_20581084_ChIP-Seq_MESCs_Mouse1.28659861
61CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.27981512
62NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.27941746
63SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.27213960
64RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.26976443
65YY1_22570637_ChIP-Seq_MALME-3M_Human1.25171938
66ZFP281_18757296_ChIP-ChIP_E14_Mouse1.24621022
67DNAJC2_21179169_ChIP-ChIP_NT2_Human1.22959092
68VDR_24763502_ChIP-Seq_THP-1_Human1.22625645
69* SA1_27219007_Chip-Seq_Bcells_Human1.22074379
70CIITA_25753668_ChIP-Seq_RAJI_Human1.21576318
71GABP_19822575_ChIP-Seq_HepG2_Human1.20355218
72SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.20127956
73RARB_24833708_ChIP-Seq_LIVER_Mouse1.19792180
74FOXP1_21924763_ChIP-Seq_HESCs_Human1.18874898
75* MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.17040251
76TP53_22127205_ChIP-Seq_IMR90_Human1.16552572
77CTCF_21964334_Chip-Seq_Bcells_Human1.16300797
78RARA_24833708_ChIP-Seq_LIVER_Mouse1.16052624
79CTCF_26484167_Chip-Seq_Bcells_Mouse1.15697090
80ZNF263_19887448_ChIP-Seq_K562_Human1.15469612
81FOXM1_23109430_ChIP-Seq_U2OS_Human1.14674355
82PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.13409887
83PU.1_20513432_ChIP-Seq_Bcells_Mouse1.12720576
84* CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.12357942
85SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.10448215
86ETS1_21867929_ChIP-Seq_TH2_Mouse1.09859230
87TP63_22573176_ChIP-Seq_HFKS_Human1.09331845
88EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.08308694
89CTCF_21964334_ChIP-Seq_BJAB-B_Human1.08043886
90* KDM5A_27292631_Chip-Seq_BREAST_Human1.07834250
91CTCF_20526341_ChIP-Seq_ESCs_Human1.07471887
92KLF4_18555785_ChIP-Seq_MESCs_Mouse1.06862238
93CTCF_18555785_ChIP-Seq_MESCs_Mouse1.06367808
94MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.05152399
95SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.04872730
96ATF3_27146783_Chip-Seq_COLON_Human1.04708234
97TP63_17297297_ChIP-ChIP_HaCaT_Human1.04260110
98YY1_21170310_ChIP-Seq_MESCs_Mouse1.04236403
99FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.03396768
100RUNX1_22412390_ChIP-Seq_EML_Mouse1.03286785

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005058_abnormal_lysosome_morphology4.01522072
2MP0008260_abnormal_autophagy3.45158848
3MP0005451_abnormal_body_composition3.30531651
4MP0009278_abnormal_bone_marrow3.00330179
5MP0000678_abnormal_parathyroid_gland2.96335881
6MP0004858_abnormal_nervous_system2.76652876
7MP0004510_myositis2.64266769
8MP0005076_abnormal_cell_differentiation2.51411209
9MP0002822_catalepsy2.45150288
10MP0003303_peritoneal_inflammation2.41406301
11MP0003705_abnormal_hypodermis_morpholog2.37074061
12MP0003172_abnormal_lysosome_physiology2.35653456
13MP0003436_decreased_susceptibility_to2.22543580
14MP0002249_abnormal_larynx_morphology2.16871245
15MP0003111_abnormal_nucleus_morphology2.13103583
16MP0001873_stomach_inflammation2.11607456
17MP0003693_abnormal_embryo_hatching2.07816755
18MP0009333_abnormal_splenocyte_physiolog2.05034505
19MP0004233_abnormal_muscle_weight2.02497271
20MP0001849_ear_inflammation1.96170058
21MP0009840_abnormal_foam_cell1.88457518
22MP0005083_abnormal_biliary_tract1.77404195
23MP0002653_abnormal_ependyma_morphology1.76072343
24MP0003453_abnormal_keratinocyte_physiol1.73893637
25MP0004947_skin_inflammation1.70992944
26MP0000003_abnormal_adipose_tissue1.65378306
27MP0003646_muscle_fatigue1.49581548
28MP0005410_abnormal_fertilization1.45870526
29MP0003077_abnormal_cell_cycle1.45010405
30MP0004185_abnormal_adipocyte_glucose1.38846152
31MP0000858_altered_metastatic_potential1.33088934
32MP0005375_adipose_tissue_phenotype1.27918379
33MP0005501_abnormal_skin_physiology1.26321247
34MP0003786_premature_aging1.25103531
35MP0005394_taste/olfaction_phenotype1.23868656
36MP0005499_abnormal_olfactory_system1.23868656
37MP0004859_abnormal_synaptic_plasticity1.21530435
38MP0005397_hematopoietic_system_phenotyp1.20373139
39MP0001545_abnormal_hematopoietic_system1.20373139
40MP0005025_abnormal_response_to1.17902117
41MP0005666_abnormal_adipose_tissue1.17469018
42MP0001348_abnormal_lacrimal_gland1.14849352
43MP0002877_abnormal_melanocyte_morpholog1.13360275
44MP0004381_abnormal_hair_follicle1.11850264
45MP0003763_abnormal_thymus_physiology1.09449280
46MP0000467_abnormal_esophagus_morphology1.08579781
47MP0000013_abnormal_adipose_tissue1.08473023
48MP0000490_abnormal_crypts_of1.06604066
49MP0000733_abnormal_muscle_development1.06244685
50MP0000358_abnormal_cell_content/1.06198833
51MP0000313_abnormal_cell_death1.04978380
52MP0008789_abnormal_olfactory_epithelium0.98584113
53MP0001730_embryonic_growth_arrest0.95474915
54MP0002089_abnormal_postnatal_growth/wei0.94867386
55MP0010094_abnormal_chromosome_stability0.94838099
56MP0003329_amyloid_beta_deposits0.94665064
57MP0010030_abnormal_orbit_morphology0.94064523
58MP0008995_early_reproductive_senescence0.93596743
59MP0002398_abnormal_bone_marrow0.90916944
60MP0008932_abnormal_embryonic_tissue0.89951812
61MP0000703_abnormal_thymus_morphology0.89471372
62MP0005621_abnormal_cell_physiology0.89222632
63MP0005000_abnormal_immune_tolerance0.88889073
64MP0001727_abnormal_embryo_implantation0.88514118
65MP0008007_abnormal_cellular_replicative0.88175714
66MP0002796_impaired_skin_barrier0.87758334
67MP0005670_abnormal_white_adipose0.87588417
68MP0005377_hearing/vestibular/ear_phenot0.87375110
69MP0003878_abnormal_ear_physiology0.87375110
70MP0001216_abnormal_epidermal_layer0.86279366
71MP0000681_abnormal_thyroid_gland0.85604850
72MP0002723_abnormal_immune_serum0.85083987
73MP0002722_abnormal_immune_system0.83098425
74MP0002254_reproductive_system_inflammat0.82894565
75MP0002080_prenatal_lethality0.81685434
76MP0002429_abnormal_blood_cell0.81520434
77MP0005310_abnormal_salivary_gland0.79739961
78MP0001819_abnormal_immune_cell0.78130872
79MP0009931_abnormal_skin_appearance0.77425678
80MP0000716_abnormal_immune_system0.77208341
81MP0002019_abnormal_tumor_incidence0.77073814
82MP0003656_abnormal_erythrocyte_physiolo0.76961464
83MP0000751_myopathy0.76033804
84MP0002405_respiratory_system_inflammati0.75547797
85MP0005384_cellular_phenotype0.75487000
86MP0002420_abnormal_adaptive_immunity0.75078266
87MP0003698_abnormal_male_reproductive0.74808151
88MP0003091_abnormal_cell_migration0.72071216
89MP0002452_abnormal_antigen_presenting0.70915409
90MP0000350_abnormal_cell_proliferation0.70823089
91MP0006035_abnormal_mitochondrial_morpho0.70247668
92MP0008874_decreased_physiological_sensi0.69865020
93MP0002419_abnormal_innate_immunity0.69158132
94MP0002970_abnormal_white_adipose0.69123718
95MP0002098_abnormal_vibrissa_morphology0.67800231
96MP0002161_abnormal_fertility/fecundity0.67712935
97MP0002933_joint_inflammation0.66497952
98MP0000750_abnormal_muscle_regeneration0.65569790
99MP0001790_abnormal_immune_system0.64588660
100MP0005387_immune_system_phenotype0.64588660

Predicted human phenotypes

RankGene SetZ-score
1Abnormal gallbladder physiology (HP:0012438)3.78598938
2Cholecystitis (HP:0001082)3.78598938
3Hyperacusis (HP:0010780)3.62983933
4Broad distal phalanx of finger (HP:0009836)3.49012616
5Reticulocytosis (HP:0001923)3.40627217
6Long palpebral fissure (HP:0000637)3.33181164
7Upper limb amyotrophy (HP:0009129)3.14267038
8Distal upper limb amyotrophy (HP:0007149)3.14267038
9Stridor (HP:0010307)2.87629777
10Flattened epiphyses (HP:0003071)2.84343837
11Distal lower limb amyotrophy (HP:0008944)2.81173208
12Ulnar bowing (HP:0003031)2.80983841
13Obstructive sleep apnea (HP:0002870)2.79667043
14Broad face (HP:0000283)2.74094676
15Abnormality of the thoracic spine (HP:0100711)2.72210718
16Hypertensive crisis (HP:0100735)2.69517410
17Abnormality of the fingertips (HP:0001211)2.59211113
18Thoracic kyphosis (HP:0002942)2.57744964
19Truncus arteriosus (HP:0001660)2.57576822
20Testicular atrophy (HP:0000029)2.51158379
21Hand muscle atrophy (HP:0009130)2.50232565
22Thin bony cortex (HP:0002753)2.49916980
23Flat capital femoral epiphysis (HP:0003370)2.49709575
24Abnormality of lateral ventricle (HP:0030047)2.45897617
25Retinal dysplasia (HP:0007973)2.45816957
26Atelectasis (HP:0100750)2.44812268
27Pointed chin (HP:0000307)2.43962696
28Dysostosis multiplex (HP:0000943)2.39003665
29J-shaped sella turcica (HP:0002680)2.37968527
30Increased cerebral lipofuscin (HP:0011813)2.37379157
31Abnormality of reticulocytes (HP:0004312)2.34609432
32Ragged-red muscle fibers (HP:0003200)2.31752050
33Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.31651013
34Disproportionate tall stature (HP:0001519)2.19598762
35Hyperthyroidism (HP:0000836)2.19296343
36Increased neuronal autofluorescent lipopigment (HP:0002074)2.14955819
37Proximal placement of thumb (HP:0009623)2.11819232
38Gastrointestinal dysmotility (HP:0002579)2.11383442
39Bowel incontinence (HP:0002607)2.10804412
40Abnormal large intestine physiology (HP:0012700)2.10607586
41Abnormality of the aortic arch (HP:0012303)2.09075925
42Interstitial pulmonary disease (HP:0006530)2.08504986
43Achilles tendon contracture (HP:0001771)2.08132138
44Sparse lateral eyebrow (HP:0005338)2.07515885
45Neuronal loss in central nervous system (HP:0002529)2.07139812
46Short 5th finger (HP:0009237)2.06125641
47Cerebral aneurysm (HP:0004944)2.06034684
48Poikiloderma (HP:0001029)2.05782281
49Patellar dislocation (HP:0002999)2.05778326
50Colitis (HP:0002583)2.05074800
51Self-mutilation (HP:0000742)2.04501668
52Cervical subluxation (HP:0003308)2.04172804
53Abnormality of polysaccharide metabolism (HP:0011012)2.03018556
54Abnormality of glycosaminoglycan metabolism (HP:0004371)2.03018556
55Abnormality of mucopolysaccharide metabolism (HP:0011020)2.03018556
56Myopathic facies (HP:0002058)2.01806701
57Aplasia/Hypoplasia of the 5th finger (HP:0006262)2.00503214
58Rough bone trabeculation (HP:0100670)2.00194415
59Loss of speech (HP:0002371)1.99824983
60Long toe (HP:0010511)1.99137905
61Intestinal fistula (HP:0100819)1.98566536
62Natal tooth (HP:0000695)1.97920884
63Abnormality of liposaccharide metabolism (HP:0010968)1.97811253
64Abnormality of glycosphingolipid metabolism (HP:0004343)1.97811253
65Abnormality of glycolipid metabolism (HP:0010969)1.97811253
66Seborrheic dermatitis (HP:0001051)1.94775478
67Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.91285732
68Absent epiphyses (HP:0010577)1.91285732
69Deviation of the thumb (HP:0009603)1.90927657
70Cholelithiasis (HP:0001081)1.90382899
71Biconcave vertebral bodies (HP:0004586)1.86254335
72Mucopolysacchariduria (HP:0008155)1.83536679
73Urinary glycosaminoglycan excretion (HP:0003541)1.83536679
74Abnormality of the columella (HP:0009929)1.83383033
75Lower limb amyotrophy (HP:0007210)1.83333257
76Insomnia (HP:0100785)1.82903346
77Chronic obstructive pulmonary disease (HP:0006510)1.82447387
78Obstructive lung disease (HP:0006536)1.82447387
79Male infertility (HP:0003251)1.81368778
80Increased serum ferritin (HP:0003281)1.80631640
81Lip pit (HP:0100267)1.78961733
82Difficulty climbing stairs (HP:0003551)1.78552547
83Hemorrhage of the eye (HP:0011885)1.78021543
84Nasal polyposis (HP:0100582)1.76855220
85Abnormality of the gallbladder (HP:0005264)1.76381174
86Dysautonomia (HP:0002459)1.75089828
87Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.74865533
88Severe visual impairment (HP:0001141)1.74501461
89Abnormal trabecular bone morphology (HP:0100671)1.73933205
90Patellar aplasia (HP:0006443)1.73722247
91Slow saccadic eye movements (HP:0000514)1.73702025
92Trismus (HP:0000211)1.73590629
93Abnormality of the distal phalanges of the toes (HP:0010182)1.73537964
94Hypoparathyroidism (HP:0000829)1.73093490
95Optic nerve coloboma (HP:0000588)1.72985403
96Ureteral stenosis (HP:0000071)1.72845654
97Selective tooth agenesis (HP:0001592)1.71813807
98Prolonged neonatal jaundice (HP:0006579)1.71520382
99Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)1.70984531
100Axonal loss (HP:0003447)1.69817389

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.57234892
2IRAK33.13183161
3SIK13.01796838
4NME22.97126209
5ICK2.92363110
6MAP3K112.59614988
7SMG12.57862080
8PRPF4B2.56720615
9RIPK12.52129414
10TESK12.47450914
11TAOK22.10832091
12ERN12.09450577
13TESK22.07098167
14SIK22.06069337
15EPHA21.94321275
16EEF2K1.86635980
17PIM21.80056745
18MAP4K11.78860870
19CDK121.69266819
20SIK31.69138432
21MST1R1.50055924
22TBK11.45609458
23MAP2K31.44682530
24MAPK151.40251846
25MAP3K31.32095343
26DDR21.27220613
27TAOK11.23820379
28ARAF1.20840182
29PKN21.17758066
30TNK21.16491284
31BMX1.13892128
32EPHB11.13552777
33KDR1.11554276
34MARK21.08400687
35MTOR1.07485411
36PRKD31.02661339
37PRKCI0.96864826
38CDC42BPA0.96574601
39RPS6KA20.93010860
40PRKD20.90006608
41RPS6KA60.88743438
42RPS6KC10.86959733
43RPS6KL10.86959733
44RPS6KA40.86922117
45IRAK20.85345400
46NME10.85089103
47PTK60.82931650
48PDPK10.82472643
49MAP3K100.81071367
50PAK40.80989797
51AURKA0.80133076
52BUB10.79524019
53CDK70.77648713
54MAPKAPK30.77250658
55BCKDK0.75856338
56IKBKE0.74893327
57CAMKK10.73378788
58BRAF0.72893628
59IRAK40.71870914
60MAPK110.71562511
61MAP3K60.69761940
62MAP3K10.67551276
63MAP3K140.67321505
64CDK40.67132241
65MAP3K80.61897053
66BRSK10.60513379
67MAP3K70.57635988
68JAK30.57053885
69DAPK10.56390945
70IKBKB0.55937950
71PAK10.55449253
72CHUK0.54589811
73CCNB10.54423681
74CDK11A0.53671938
75RIPK40.53221310
76CHEK20.52632771
77TTN0.52410846
78PTK20.51846753
79CAMK1D0.51469083
80TYRO30.50953810
81BLK0.50482835
82MARK30.49817691
83MATK0.47428672
84CAMK40.45907143
85KSR20.45206759
86TYK20.44976317
87BTK0.44522291
88GRK60.44426184
89DYRK1B0.42304393
90CHEK10.41511134
91MAP2K20.41437729
92ZAP700.40067257
93CDK150.39740079
94FGFR40.39692065
95HIPK20.36958537
96MAP3K90.36498988
97CDK20.36384848
98CDK180.35050766
99CDK140.34769040
100MAP2K60.34599788

Predicted pathways (KEGG)

RankGene SetZ-score
1Sulfur relay system_Homo sapiens_hsa041223.92630305
2Other glycan degradation_Homo sapiens_hsa005113.50257067
3Acute myeloid leukemia_Homo sapiens_hsa052212.64789002
4Glycosaminoglycan degradation_Homo sapiens_hsa005312.41280484
5Fructose and mannose metabolism_Homo sapiens_hsa000512.27961021
6Notch signaling pathway_Homo sapiens_hsa043302.05458222
7Base excision repair_Homo sapiens_hsa034101.98763710
8RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.93873616
9VEGF signaling pathway_Homo sapiens_hsa043701.73981042
10Lysine degradation_Homo sapiens_hsa003101.72843226
11Bladder cancer_Homo sapiens_hsa052191.71314580
12Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.71055730
13Toll-like receptor signaling pathway_Homo sapiens_hsa046201.68166188
14Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.66993544
15Chronic myeloid leukemia_Homo sapiens_hsa052201.65254503
16Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.56337085
17Cyanoamino acid metabolism_Homo sapiens_hsa004601.46895656
18DNA replication_Homo sapiens_hsa030301.46387228
19Central carbon metabolism in cancer_Homo sapiens_hsa052301.44734404
20Biosynthesis of amino acids_Homo sapiens_hsa012301.44543184
21Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.37031652
22Pentose phosphate pathway_Homo sapiens_hsa000301.35112966
23Lysosome_Homo sapiens_hsa041421.33831159
24Shigellosis_Homo sapiens_hsa051311.32080535
25TNF signaling pathway_Homo sapiens_hsa046681.30824997
26ErbB signaling pathway_Homo sapiens_hsa040121.30641138
27Pancreatic cancer_Homo sapiens_hsa052121.30499647
28NF-kappa B signaling pathway_Homo sapiens_hsa040641.26896426
29mTOR signaling pathway_Homo sapiens_hsa041501.26689367
30Non-small cell lung cancer_Homo sapiens_hsa052231.25929660
31Salmonella infection_Homo sapiens_hsa051321.20947582
32Osteoclast differentiation_Homo sapiens_hsa043801.17023016
33Pyrimidine metabolism_Homo sapiens_hsa002401.16914670
34Hepatitis C_Homo sapiens_hsa051601.13173737
35Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.08389074
36Epstein-Barr virus infection_Homo sapiens_hsa051691.07759990
37Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.06496561
38Neurotrophin signaling pathway_Homo sapiens_hsa047221.05896818
39Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.05379374
40Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.04854639
41Hepatitis B_Homo sapiens_hsa051611.03625845
42Apoptosis_Homo sapiens_hsa042101.03075533
43B cell receptor signaling pathway_Homo sapiens_hsa046621.01876276
44Longevity regulating pathway - mammal_Homo sapiens_hsa042110.98709878
452-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.96495772
46Influenza A_Homo sapiens_hsa051640.94951370
47Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.93225832
48Endocytosis_Homo sapiens_hsa041440.92578572
49Herpes simplex infection_Homo sapiens_hsa051680.89344706
50Viral carcinogenesis_Homo sapiens_hsa052030.89093047
51AMPK signaling pathway_Homo sapiens_hsa041520.87230623
52Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.87179846
53Prion diseases_Homo sapiens_hsa050200.87023725
54Choline metabolism in cancer_Homo sapiens_hsa052310.85962823
55Insulin signaling pathway_Homo sapiens_hsa049100.85954371
56Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.85697766
57Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.85160292
58Adipocytokine signaling pathway_Homo sapiens_hsa049200.83963814
59Synaptic vesicle cycle_Homo sapiens_hsa047210.82969514
60Galactose metabolism_Homo sapiens_hsa000520.82559500
61Cell cycle_Homo sapiens_hsa041100.80410775
62Endometrial cancer_Homo sapiens_hsa052130.78940728
63HTLV-I infection_Homo sapiens_hsa051660.78093728
64Vibrio cholerae infection_Homo sapiens_hsa051100.77601098
65mRNA surveillance pathway_Homo sapiens_hsa030150.77218256
66Homologous recombination_Homo sapiens_hsa034400.76609838
67T cell receptor signaling pathway_Homo sapiens_hsa046600.76434066
68Thyroid hormone signaling pathway_Homo sapiens_hsa049190.75556432
69Toxoplasmosis_Homo sapiens_hsa051450.75095323
70Fanconi anemia pathway_Homo sapiens_hsa034600.72568199
71Phospholipase D signaling pathway_Homo sapiens_hsa040720.72503730
72Spliceosome_Homo sapiens_hsa030400.72171499
73N-Glycan biosynthesis_Homo sapiens_hsa005100.71516691
74Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.71446498
75Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.71094544
76Sphingolipid metabolism_Homo sapiens_hsa006000.67672071
77AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.67579838
78Glioma_Homo sapiens_hsa052140.67131869
79Prolactin signaling pathway_Homo sapiens_hsa049170.67131757
80Sphingolipid signaling pathway_Homo sapiens_hsa040710.66881796
81Glycerophospholipid metabolism_Homo sapiens_hsa005640.65968507
82NOD-like receptor signaling pathway_Homo sapiens_hsa046210.65335667
83HIF-1 signaling pathway_Homo sapiens_hsa040660.64688367
84Malaria_Homo sapiens_hsa051440.63187137
85Phosphatidylinositol signaling system_Homo sapiens_hsa040700.63003100
86Pertussis_Homo sapiens_hsa051330.61239948
87Tuberculosis_Homo sapiens_hsa051520.60793049
88Measles_Homo sapiens_hsa051620.59840105
89Inositol phosphate metabolism_Homo sapiens_hsa005620.57296984
90Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.56978664
91Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.55968109
92Insulin resistance_Homo sapiens_hsa049310.54119857
93Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.53171052
94Leishmaniasis_Homo sapiens_hsa051400.52747273
95Legionellosis_Homo sapiens_hsa051340.52479296
96Colorectal cancer_Homo sapiens_hsa052100.50537546
97Small cell lung cancer_Homo sapiens_hsa052220.47219855
98Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.44804815
99Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.44176912
100RNA transport_Homo sapiens_hsa030130.42693091

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »