

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | synaptic vesicle maturation (GO:0016188) | 8.99323402 |
| 2 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 7.89336445 |
| 3 | synaptic vesicle exocytosis (GO:0016079) | 7.42469832 |
| 4 | glutamate secretion (GO:0014047) | 7.34253523 |
| 5 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 7.24256900 |
| 6 | regulation of synaptic vesicle exocytosis (GO:2000300) | 6.75586709 |
| 7 | regulation of synaptic vesicle transport (GO:1902803) | 6.00717976 |
| 8 | neurotransmitter secretion (GO:0007269) | 5.60146821 |
| 9 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 5.25124594 |
| 10 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 5.22420789 |
| 11 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 5.17093916 |
| 12 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 5.03612261 |
| 13 | neuronal action potential propagation (GO:0019227) | 4.96652991 |
| 14 | regulation of synapse structural plasticity (GO:0051823) | 4.80299780 |
| 15 | regulation of neuronal synaptic plasticity (GO:0048168) | 4.67495139 |
| 16 | synaptic transmission, glutamatergic (GO:0035249) | 4.57418088 |
| 17 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 4.55015524 |
| 18 | cellular potassium ion homeostasis (GO:0030007) | 4.44224100 |
| 19 | gamma-aminobutyric acid transport (GO:0015812) | 4.43595408 |
| 20 | neurotransmitter transport (GO:0006836) | 4.36163261 |
| 21 | locomotory exploration behavior (GO:0035641) | 4.35006346 |
| 22 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 4.21584368 |
| 23 | regulation of neurotransmitter secretion (GO:0046928) | 4.20817616 |
| 24 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 4.17969853 |
| 25 | protein localization to synapse (GO:0035418) | 4.17300226 |
| 26 | regulation of vesicle fusion (GO:0031338) | 4.14031443 |
| 27 | neuron-neuron synaptic transmission (GO:0007270) | 4.09318735 |
| 28 | synaptic vesicle endocytosis (GO:0048488) | 4.06628382 |
| 29 | regulation of neurotransmitter levels (GO:0001505) | 4.06205899 |
| 30 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 4.05130014 |
| 31 | establishment of mitochondrion localization (GO:0051654) | 4.01684891 |
| 32 | vocalization behavior (GO:0071625) | 3.98141319 |
| 33 | exploration behavior (GO:0035640) | 3.97379422 |
| 34 | positive regulation of neurotransmitter secretion (GO:0001956) | 3.95905167 |
| 35 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 3.95867125 |
| 36 | amino acid import (GO:0043090) | 3.95824507 |
| 37 | L-amino acid import (GO:0043092) | 3.94332089 |
| 38 | sodium ion export (GO:0071436) | 3.94100581 |
| 39 | proline transport (GO:0015824) | 3.93980717 |
| 40 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.93597285 |
| 41 | neuron cell-cell adhesion (GO:0007158) | 3.90326991 |
| 42 | layer formation in cerebral cortex (GO:0021819) | 3.80886385 |
| 43 | regulation of voltage-gated calcium channel activity (GO:1901385) | 3.79435817 |
| 44 | regulation of neurotransmitter transport (GO:0051588) | 3.76705135 |
| 45 | positive regulation of neurotransmitter transport (GO:0051590) | 3.69264894 |
| 46 | regulation of glutamate receptor signaling pathway (GO:1900449) | 3.68910101 |
| 47 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 3.67900493 |
| 48 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 3.67205698 |
| 49 | positive regulation of synapse maturation (GO:0090129) | 3.64404880 |
| 50 | postsynaptic membrane organization (GO:0001941) | 3.62170023 |
| 51 | regulation of synaptic plasticity (GO:0048167) | 3.61317195 |
| 52 | vesicle docking involved in exocytosis (GO:0006904) | 3.58979261 |
| 53 | positive regulation of membrane potential (GO:0045838) | 3.57509927 |
| 54 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.56001582 |
| 55 | glutamate receptor signaling pathway (GO:0007215) | 3.55439933 |
| 56 | positive regulation of dendritic spine development (GO:0060999) | 3.52701555 |
| 57 | neuronal ion channel clustering (GO:0045161) | 3.49292865 |
| 58 | acidic amino acid transport (GO:0015800) | 3.48153556 |
| 59 | dendritic spine morphogenesis (GO:0060997) | 3.47628332 |
| 60 | glycosphingolipid biosynthetic process (GO:0006688) | 3.41388337 |
| 61 | synaptic vesicle transport (GO:0048489) | 3.39568343 |
| 62 | establishment of synaptic vesicle localization (GO:0097480) | 3.39568343 |
| 63 | pyrimidine nucleobase catabolic process (GO:0006208) | 3.39329757 |
| 64 | regulation of postsynaptic membrane potential (GO:0060078) | 3.35128741 |
| 65 | membrane depolarization during action potential (GO:0086010) | 3.33488194 |
| 66 | vesicle docking (GO:0048278) | 3.30132055 |
| 67 | negative regulation of dendrite morphogenesis (GO:0050774) | 3.28772470 |
| 68 | neuromuscular synaptic transmission (GO:0007274) | 3.24534904 |
| 69 | membrane depolarization (GO:0051899) | 3.23240668 |
| 70 | neuromuscular process controlling balance (GO:0050885) | 3.23149904 |
| 71 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 3.22792533 |
| 72 | synaptic transmission (GO:0007268) | 3.21898946 |
| 73 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 3.21504260 |
| 74 | cerebellar granule cell differentiation (GO:0021707) | 3.20391286 |
| 75 | neuromuscular process controlling posture (GO:0050884) | 3.14720117 |
| 76 | regulation of synaptic transmission (GO:0050804) | 3.10668222 |
| 77 | regulation of dendritic spine morphogenesis (GO:0061001) | 3.08664562 |
| 78 | L-glutamate transport (GO:0015813) | 3.03356387 |
| 79 | cerebellar Purkinje cell differentiation (GO:0021702) | 3.02721957 |
| 80 | cell migration in hindbrain (GO:0021535) | 3.01271607 |
| 81 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 2.99589536 |
| 82 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 2.99212876 |
| 83 | ATP hydrolysis coupled proton transport (GO:0015991) | 2.99212876 |
| 84 | mitochondrion transport along microtubule (GO:0047497) | 2.97915260 |
| 85 | establishment of mitochondrion localization, microtubule-mediated (GO:0034643) | 2.97915260 |
| 86 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 2.96574817 |
| 87 | regulation of exocytosis (GO:0017157) | 2.94781826 |
| 88 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 2.93968532 |
| 89 | detection of calcium ion (GO:0005513) | 2.92941934 |
| 90 | regulation of dendritic spine development (GO:0060998) | 2.92398381 |
| 91 | dicarboxylic acid transport (GO:0006835) | 2.92136994 |
| 92 | long-term memory (GO:0007616) | 2.91910254 |
| 93 | long-term synaptic potentiation (GO:0060291) | 2.91525211 |
| 94 | dendritic spine organization (GO:0097061) | 2.91190649 |
| 95 | neurotransmitter uptake (GO:0001504) | 2.89152043 |
| 96 | signal release (GO:0023061) | 2.89018499 |
| 97 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 2.88534441 |
| 98 | nucleobase catabolic process (GO:0046113) | 2.87726712 |
| 99 | regulation of synapse maturation (GO:0090128) | 2.85975486 |
| 100 | positive regulation of synaptic transmission (GO:0050806) | 2.82582512 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.94893687 |
| 2 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 4.71534895 |
| 3 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 3.93523941 |
| 4 | REST_21632747_ChIP-Seq_MESCs_Mouse | 3.51450671 |
| 5 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 3.33928003 |
| 6 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 3.25793945 |
| 7 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 3.09517688 |
| 8 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.82316460 |
| 9 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.81720573 |
| 10 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.78948309 |
| 11 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.71607481 |
| 12 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.68130505 |
| 13 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.67469649 |
| 14 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.62226584 |
| 15 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.61812239 |
| 16 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.56462776 |
| 17 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.43787955 |
| 18 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 2.39897689 |
| 19 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.39634179 |
| 20 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 2.38126128 |
| 21 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.35872461 |
| 22 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.35872461 |
| 23 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.34503591 |
| 24 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.31002481 |
| 25 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.29754154 |
| 26 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.26295761 |
| 27 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 2.25498600 |
| 28 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 2.15405276 |
| 29 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.13626053 |
| 30 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.12178127 |
| 31 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.99015529 |
| 32 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.93589814 |
| 33 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.85785436 |
| 34 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.75002767 |
| 35 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 1.74927316 |
| 36 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.68697089 |
| 37 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.66267443 |
| 38 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.59688202 |
| 39 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.53781937 |
| 40 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.53398478 |
| 41 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.52538287 |
| 42 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.45087410 |
| 43 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.34617450 |
| 44 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.34203513 |
| 45 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.32892545 |
| 46 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.28718830 |
| 47 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.28166890 |
| 48 | * KDM2B_26808549_Chip-Seq_K562_Human | 1.25490040 |
| 49 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.25355953 |
| 50 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.25348436 |
| 51 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.23655914 |
| 52 | OCT4_19829295_ChIP-Seq_ESCs_Human | 1.21461449 |
| 53 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.21333219 |
| 54 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.20787565 |
| 55 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 1.13066723 |
| 56 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.11493313 |
| 57 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.11378687 |
| 58 | P68_20966046_ChIP-Seq_HELA_Human | 1.07736127 |
| 59 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.07451808 |
| 60 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.01943956 |
| 61 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.01868972 |
| 62 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.01688474 |
| 63 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 0.99537356 |
| 64 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 0.95768678 |
| 65 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.95208564 |
| 66 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 0.93699526 |
| 67 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.91649827 |
| 68 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.91631963 |
| 69 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.90090805 |
| 70 | SETDB1_19884255_ChIP-Seq_MESCs_Mouse | 0.89086814 |
| 71 | TFAP2A_17053090_ChIP-ChIP_MCF-7_Human | 0.87811184 |
| 72 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.84374770 |
| 73 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.83680996 |
| 74 | NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse | 0.82786638 |
| 75 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.82681615 |
| 76 | * MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 0.80906579 |
| 77 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.80051463 |
| 78 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.79984724 |
| 79 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 0.79712442 |
| 80 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 0.79631305 |
| 81 | * SA1_27219007_Chip-Seq_Bcells_Human | 0.78328026 |
| 82 | TP53_23651856_ChIP-Seq_MEFs_Mouse | 0.78193115 |
| 83 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.78103419 |
| 84 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.77462852 |
| 85 | AR_19668381_ChIP-Seq_PC3_Human | 0.76878605 |
| 86 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.76818261 |
| 87 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.76586644 |
| 88 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 0.76270231 |
| 89 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.75170907 |
| 90 | SOX3_22085726_ChIP-Seq_MUSCLE_Mouse | 0.75094182 |
| 91 | DPY_21335234_ChIP-Seq_ESCs_Mouse | 0.75016648 |
| 92 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 0.74260463 |
| 93 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 0.73581550 |
| 94 | KLF4_19829295_ChIP-Seq_ESCs_Human | 0.73341690 |
| 95 | AR_21572438_ChIP-Seq_LNCaP_Human | 0.73040506 |
| 96 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 0.72713344 |
| 97 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 0.71712992 |
| 98 | * KDM2B_26808549_Chip-Seq_DND41_Human | 0.71345808 |
| 99 | TP53_22127205_ChIP-Seq_IMR90_Human | 0.70663908 |
| 100 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.69041082 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0004859_abnormal_synaptic_plasticity | 6.54972182 |
| 2 | MP0003880_abnormal_central_pattern | 4.78329627 |
| 3 | MP0004270_analgesia | 4.12437341 |
| 4 | MP0003635_abnormal_synaptic_transmissio | 4.06726178 |
| 5 | MP0002064_seizures | 3.58315755 |
| 6 | MP0005423_abnormal_somatic_nervous | 3.40639769 |
| 7 | MP0001968_abnormal_touch/_nociception | 3.39022762 |
| 8 | MP0002063_abnormal_learning/memory/cond | 3.29293673 |
| 9 | MP0009745_abnormal_behavioral_response | 3.29107715 |
| 10 | MP0009046_muscle_twitch | 3.27672367 |
| 11 | MP0002272_abnormal_nervous_system | 3.01544891 |
| 12 | MP0002572_abnormal_emotion/affect_behav | 2.73045659 |
| 13 | MP0002734_abnormal_mechanical_nocicepti | 2.68181325 |
| 14 | MP0001486_abnormal_startle_reflex | 2.64832067 |
| 15 | MP0002736_abnormal_nociception_after | 2.60674826 |
| 16 | MP0001501_abnormal_sleep_pattern | 2.42754502 |
| 17 | MP0002735_abnormal_chemical_nociception | 2.40150924 |
| 18 | MP0003329_amyloid_beta_deposits | 2.38004704 |
| 19 | MP0008569_lethality_at_weaning | 2.22487742 |
| 20 | MP0002733_abnormal_thermal_nociception | 2.10648335 |
| 21 | MP0001970_abnormal_pain_threshold | 2.09321766 |
| 22 | MP0004811_abnormal_neuron_physiology | 1.90303089 |
| 23 | MP0003787_abnormal_imprinting | 1.88310253 |
| 24 | MP0006276_abnormal_autonomic_nervous | 1.86471976 |
| 25 | MP0005646_abnormal_pituitary_gland | 1.81057692 |
| 26 | MP0001905_abnormal_dopamine_level | 1.77810950 |
| 27 | MP0002067_abnormal_sensory_capabilities | 1.74984638 |
| 28 | MP0003879_abnormal_hair_cell | 1.72542181 |
| 29 | MP0002557_abnormal_social/conspecific_i | 1.69455179 |
| 30 | MP0001440_abnormal_grooming_behavior | 1.53729377 |
| 31 | MP0003633_abnormal_nervous_system | 1.50514324 |
| 32 | MP0000778_abnormal_nervous_system | 1.49070911 |
| 33 | MP0002066_abnormal_motor_capabilities/c | 1.48664748 |
| 34 | MP0005386_behavior/neurological_phenoty | 1.47594092 |
| 35 | MP0004924_abnormal_behavior | 1.47594092 |
| 36 | MP0000920_abnormal_myelination | 1.47535372 |
| 37 | MP0004147_increased_porphyrin_level | 1.47464869 |
| 38 | MP0001502_abnormal_circadian_rhythm | 1.46006488 |
| 39 | MP0002882_abnormal_neuron_morphology | 1.41770448 |
| 40 | MP0001984_abnormal_olfaction | 1.40047003 |
| 41 | MP0000604_amyloidosis | 1.35334635 |
| 42 | MP0002184_abnormal_innervation | 1.29590739 |
| 43 | MP0003631_nervous_system_phenotype | 1.29205851 |
| 44 | MP0010386_abnormal_urinary_bladder | 1.29184127 |
| 45 | MP0001986_abnormal_taste_sensitivity | 1.28980165 |
| 46 | MP0000955_abnormal_spinal_cord | 1.27692617 |
| 47 | MP0003690_abnormal_glial_cell | 1.19856810 |
| 48 | MP0001177_atelectasis | 1.18979856 |
| 49 | MP0004885_abnormal_endolymph | 1.16813543 |
| 50 | MP0003075_altered_response_to | 1.16672598 |
| 51 | MP0002229_neurodegeneration | 1.16671945 |
| 52 | MP0003172_abnormal_lysosome_physiology | 1.16082404 |
| 53 | MP0002822_catalepsy | 1.13671080 |
| 54 | MP0003634_abnormal_glial_cell | 1.08715148 |
| 55 | MP0001529_abnormal_vocalization | 1.08389166 |
| 56 | MP0005645_abnormal_hypothalamus_physiol | 1.04622795 |
| 57 | MP0000751_myopathy | 1.02732604 |
| 58 | MP0008874_decreased_physiological_sensi | 1.01857612 |
| 59 | MP0001188_hyperpigmentation | 1.00913602 |
| 60 | MP0005499_abnormal_olfactory_system | 1.00283240 |
| 61 | MP0005394_taste/olfaction_phenotype | 1.00283240 |
| 62 | MP0002152_abnormal_brain_morphology | 0.97485682 |
| 63 | MP0005167_abnormal_blood-brain_barrier | 0.96825513 |
| 64 | MP0005551_abnormal_eye_electrophysiolog | 0.94082419 |
| 65 | MP0001348_abnormal_lacrimal_gland | 0.92505676 |
| 66 | MP0004142_abnormal_muscle_tone | 0.91513843 |
| 67 | MP0005535_abnormal_body_temperature | 0.89371609 |
| 68 | MP0002638_abnormal_pupillary_reflex | 0.88706617 |
| 69 | MP0005623_abnormal_meninges_morphology | 0.85944429 |
| 70 | MP0001963_abnormal_hearing_physiology | 0.85144375 |
| 71 | MP0005171_absent_coat_pigmentation | 0.84678043 |
| 72 | MP0004742_abnormal_vestibular_system | 0.82878377 |
| 73 | MP0003632_abnormal_nervous_system | 0.81404186 |
| 74 | MP0005058_abnormal_lysosome_morphology | 0.77153085 |
| 75 | MP0002069_abnormal_eating/drinking_beha | 0.76913811 |
| 76 | MP0000013_abnormal_adipose_tissue | 0.76880162 |
| 77 | MP0008872_abnormal_physiological_respon | 0.74076167 |
| 78 | MP0003122_maternal_imprinting | 0.72507565 |
| 79 | MP0009780_abnormal_chondrocyte_physiolo | 0.70781926 |
| 80 | MP0002752_abnormal_somatic_nervous | 0.69384536 |
| 81 | MP0006035_abnormal_mitochondrial_morpho | 0.68298404 |
| 82 | MP0009278_abnormal_bone_marrow | 0.65399346 |
| 83 | MP0006036_abnormal_mitochondrial_physio | 0.62007764 |
| 84 | MP0003123_paternal_imprinting | 0.61640252 |
| 85 | MP0002102_abnormal_ear_morphology | 0.60400294 |
| 86 | MP0003137_abnormal_impulse_conducting | 0.55807677 |
| 87 | MP0002332_abnormal_exercise_endurance | 0.54857704 |
| 88 | MP0002909_abnormal_adrenal_gland | 0.54713905 |
| 89 | MP0002090_abnormal_vision | 0.53403018 |
| 90 | MP0001542_abnormal_bone_strength | 0.52827708 |
| 91 | MP0010769_abnormal_survival | 0.51635506 |
| 92 | MP0000747_muscle_weakness | 0.50946765 |
| 93 | MP0005253_abnormal_eye_physiology | 0.50875532 |
| 94 | MP0000569_abnormal_digit_pigmentation | 0.50409618 |
| 95 | MP0004130_abnormal_muscle_cell | 0.50035671 |
| 96 | MP0004043_abnormal_pH_regulation | 0.49915133 |
| 97 | MP0001943_abnormal_respiration | 0.49697504 |
| 98 | MP0002653_abnormal_ependyma_morphology | 0.49645358 |
| 99 | MP0010768_mortality/aging | 0.49143796 |
| 100 | MP0004085_abnormal_heartbeat | 0.47904479 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Myokymia (HP:0002411) | 6.84115177 |
| 2 | Focal motor seizures (HP:0011153) | 6.67370427 |
| 3 | Focal seizures (HP:0007359) | 5.64143832 |
| 4 | Epileptic encephalopathy (HP:0200134) | 4.71779760 |
| 5 | Supranuclear gaze palsy (HP:0000605) | 4.66648276 |
| 6 | Atonic seizures (HP:0010819) | 4.52106050 |
| 7 | Ankle clonus (HP:0011448) | 4.51634479 |
| 8 | Febrile seizures (HP:0002373) | 4.50853040 |
| 9 | Visual hallucinations (HP:0002367) | 4.44012408 |
| 10 | Action tremor (HP:0002345) | 4.30735798 |
| 11 | Mutism (HP:0002300) | 4.26163922 |
| 12 | Spastic gait (HP:0002064) | 3.80998041 |
| 13 | Diplopia (HP:0000651) | 3.79440398 |
| 14 | Abnormality of binocular vision (HP:0011514) | 3.79440398 |
| 15 | Generalized tonic-clonic seizures (HP:0002069) | 3.75318660 |
| 16 | Neurofibrillary tangles (HP:0002185) | 3.69388157 |
| 17 | Delusions (HP:0000746) | 3.55354637 |
| 18 | Dialeptic seizures (HP:0011146) | 3.51954220 |
| 19 | Cerebral hypomyelination (HP:0006808) | 3.39812593 |
| 20 | Truncal ataxia (HP:0002078) | 3.36790770 |
| 21 | Abnormal eating behavior (HP:0100738) | 3.25625845 |
| 22 | Absence seizures (HP:0002121) | 3.25118836 |
| 23 | Cerebral inclusion bodies (HP:0100314) | 3.23625422 |
| 24 | Tetraplegia (HP:0002445) | 3.20282424 |
| 25 | Limb dystonia (HP:0002451) | 3.19110882 |
| 26 | Progressive cerebellar ataxia (HP:0002073) | 3.18374439 |
| 27 | Poor eye contact (HP:0000817) | 3.03344662 |
| 28 | Urinary urgency (HP:0000012) | 3.03033745 |
| 29 | Papilledema (HP:0001085) | 3.02384421 |
| 30 | Urinary bladder sphincter dysfunction (HP:0002839) | 3.01356368 |
| 31 | Torticollis (HP:0000473) | 2.96372128 |
| 32 | Insomnia (HP:0100785) | 2.91462021 |
| 33 | Lower limb muscle weakness (HP:0007340) | 2.91212058 |
| 34 | Focal dystonia (HP:0004373) | 2.91011256 |
| 35 | Intention tremor (HP:0002080) | 2.86417524 |
| 36 | Dysmetria (HP:0001310) | 2.85255943 |
| 37 | Postural instability (HP:0002172) | 2.83116133 |
| 38 | Depression (HP:0000716) | 2.82308408 |
| 39 | Status epilepticus (HP:0002133) | 2.82047950 |
| 40 | Hemiparesis (HP:0001269) | 2.80824265 |
| 41 | Neuronal loss in central nervous system (HP:0002529) | 2.80770710 |
| 42 | Annular pancreas (HP:0001734) | 2.80622283 |
| 43 | Peripheral hypomyelination (HP:0007182) | 2.79604012 |
| 44 | Clonus (HP:0002169) | 2.77444744 |
| 45 | Amyotrophic lateral sclerosis (HP:0007354) | 2.73920463 |
| 46 | Absent speech (HP:0001344) | 2.69320508 |
| 47 | Epileptiform EEG discharges (HP:0011182) | 2.68534312 |
| 48 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.65103067 |
| 49 | Craniofacial dystonia (HP:0012179) | 2.64764950 |
| 50 | Spastic tetraparesis (HP:0001285) | 2.64106485 |
| 51 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.61826159 |
| 52 | Diminished motivation (HP:0000745) | 2.60479644 |
| 53 | Apathy (HP:0000741) | 2.57820330 |
| 54 | Bradykinesia (HP:0002067) | 2.56338993 |
| 55 | Polyphagia (HP:0002591) | 2.49715666 |
| 56 | EEG with generalized epileptiform discharges (HP:0011198) | 2.44607225 |
| 57 | Dysdiadochokinesis (HP:0002075) | 2.39569817 |
| 58 | Failure to thrive in infancy (HP:0001531) | 2.36009531 |
| 59 | Progressive microcephaly (HP:0000253) | 2.35715968 |
| 60 | Hypsarrhythmia (HP:0002521) | 2.33177917 |
| 61 | Abnormality of the lower motor neuron (HP:0002366) | 2.32301420 |
| 62 | Akinesia (HP:0002304) | 2.32145605 |
| 63 | Spastic tetraplegia (HP:0002510) | 2.25860538 |
| 64 | Amblyopia (HP:0000646) | 2.23819344 |
| 65 | Hemiplegia (HP:0002301) | 2.20417533 |
| 66 | Unsteady gait (HP:0002317) | 2.20250140 |
| 67 | CNS hypomyelination (HP:0003429) | 2.20070220 |
| 68 | Abnormal social behavior (HP:0012433) | 2.18307185 |
| 69 | Impaired social interactions (HP:0000735) | 2.18307185 |
| 70 | Drooling (HP:0002307) | 2.17831467 |
| 71 | Scanning speech (HP:0002168) | 2.13317584 |
| 72 | Impaired smooth pursuit (HP:0007772) | 2.12993709 |
| 73 | Inability to walk (HP:0002540) | 2.12272246 |
| 74 | Anxiety (HP:0000739) | 2.08209201 |
| 75 | Ulnar claw (HP:0001178) | 2.08074863 |
| 76 | Abnormality of the corticospinal tract (HP:0002492) | 2.08021734 |
| 77 | Broad-based gait (HP:0002136) | 2.06670459 |
| 78 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 2.03664811 |
| 79 | Emotional lability (HP:0000712) | 2.02028896 |
| 80 | Excessive salivation (HP:0003781) | 2.01231171 |
| 81 | Rigidity (HP:0002063) | 2.00081773 |
| 82 | Rapidly progressive (HP:0003678) | 1.99395237 |
| 83 | Progressive inability to walk (HP:0002505) | 1.97925486 |
| 84 | Impaired vibratory sensation (HP:0002495) | 1.94010595 |
| 85 | Prolonged QT interval (HP:0001657) | 1.92500571 |
| 86 | Choreoathetosis (HP:0001266) | 1.89531765 |
| 87 | Abnormality of ocular smooth pursuit (HP:0000617) | 1.87501754 |
| 88 | Ragged-red muscle fibers (HP:0003200) | 1.86880531 |
| 89 | Paraplegia (HP:0010550) | 1.85866824 |
| 90 | Hand muscle atrophy (HP:0009130) | 1.83804520 |
| 91 | Decreased number of large peripheral myelinated nerve fibers (HP:0003387) | 1.83686017 |
| 92 | Limb ataxia (HP:0002070) | 1.82347006 |
| 93 | Abnormality of liposaccharide metabolism (HP:0010968) | 1.82288316 |
| 94 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 1.82288316 |
| 95 | Abnormality of glycolipid metabolism (HP:0010969) | 1.82288316 |
| 96 | Abnormal EKG (HP:0003115) | 1.81594310 |
| 97 | Hyperacusis (HP:0010780) | 1.76531241 |
| 98 | Stereotypic behavior (HP:0000733) | 1.76004294 |
| 99 | Gaze-evoked nystagmus (HP:0000640) | 1.75961600 |
| 100 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.75933845 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EPHA4 | 4.80057047 |
| 2 | MARK1 | 4.14159057 |
| 3 | DAPK2 | 3.73465623 |
| 4 | PAK6 | 3.69933353 |
| 5 | NTRK3 | 2.96476278 |
| 6 | MINK1 | 2.15184806 |
| 7 | NTRK1 | 2.12410118 |
| 8 | PLK2 | 2.05301111 |
| 9 | CAMKK1 | 2.04376989 |
| 10 | ARAF | 1.97846643 |
| 11 | PRKD3 | 1.86548369 |
| 12 | DAPK1 | 1.85235525 |
| 13 | MAP3K11 | 1.83948016 |
| 14 | NTRK2 | 1.78534505 |
| 15 | SIK2 | 1.76675088 |
| 16 | MAP2K7 | 1.74659304 |
| 17 | CDK19 | 1.73431062 |
| 18 | PHKG2 | 1.65412316 |
| 19 | PHKG1 | 1.65412316 |
| 20 | GRK5 | 1.64620995 |
| 21 | MAPK13 | 1.64594448 |
| 22 | PINK1 | 1.63631532 |
| 23 | UHMK1 | 1.60780920 |
| 24 | LIMK1 | 1.57769655 |
| 25 | MAP3K4 | 1.56385512 |
| 26 | MAP3K9 | 1.48138327 |
| 27 | CAMKK2 | 1.45088218 |
| 28 | CDK5 | 1.44128898 |
| 29 | MAP4K2 | 1.36601028 |
| 30 | CSNK1G2 | 1.36208884 |
| 31 | PIM2 | 1.34659275 |
| 32 | RIPK4 | 1.32299856 |
| 33 | PRKCG | 1.31300274 |
| 34 | CCNB1 | 1.29900421 |
| 35 | MAP2K4 | 1.25044754 |
| 36 | CDK14 | 1.23982792 |
| 37 | CDK15 | 1.22172145 |
| 38 | CDK18 | 1.20173285 |
| 39 | CDK11A | 1.15695434 |
| 40 | CSNK1G3 | 1.12429058 |
| 41 | CASK | 1.10799764 |
| 42 | CSNK1A1L | 1.09908308 |
| 43 | SCYL2 | 1.07019485 |
| 44 | CAMK1 | 1.06634828 |
| 45 | CAMK2B | 1.00549110 |
| 46 | TESK1 | 0.97631596 |
| 47 | CAMK2A | 0.90440959 |
| 48 | LATS2 | 0.86661289 |
| 49 | PRKCH | 0.86015925 |
| 50 | MAP3K6 | 0.80911724 |
| 51 | BCKDK | 0.80796770 |
| 52 | MAPK12 | 0.80196798 |
| 53 | DYRK1A | 0.79541973 |
| 54 | DAPK3 | 0.79415794 |
| 55 | ALK | 0.78372180 |
| 56 | CAMK2G | 0.73308570 |
| 57 | BRAF | 0.71379172 |
| 58 | STK16 | 0.68217271 |
| 59 | FES | 0.66430676 |
| 60 | MARK2 | 0.65903850 |
| 61 | BMPR2 | 0.65704445 |
| 62 | BCR | 0.65152393 |
| 63 | TESK2 | 0.63470924 |
| 64 | RAF1 | 0.63091336 |
| 65 | MAP2K6 | 0.63054950 |
| 66 | STK38 | 0.61930737 |
| 67 | CSNK1G1 | 0.61784863 |
| 68 | ABL2 | 0.61477542 |
| 69 | PKN1 | 0.61406835 |
| 70 | KSR2 | 0.60230909 |
| 71 | PAK3 | 0.59494375 |
| 72 | STK11 | 0.57728643 |
| 73 | PRKCE | 0.57659492 |
| 74 | OXSR1 | 0.56338000 |
| 75 | DYRK2 | 0.53728418 |
| 76 | MAP3K5 | 0.53695727 |
| 77 | PRPF4B | 0.51839670 |
| 78 | RIPK1 | 0.50814345 |
| 79 | CAMK4 | 0.48050168 |
| 80 | PDK1 | 0.46016816 |
| 81 | SGK494 | 0.45162355 |
| 82 | SGK223 | 0.45162355 |
| 83 | TAOK2 | 0.44988190 |
| 84 | PDPK1 | 0.42949880 |
| 85 | MAP3K12 | 0.42490257 |
| 86 | GRK7 | 0.42443782 |
| 87 | MAPK10 | 0.42323105 |
| 88 | TYRO3 | 0.42081590 |
| 89 | IRAK3 | 0.40470234 |
| 90 | PRKCZ | 0.40108004 |
| 91 | MAPKAPK5 | 0.39742022 |
| 92 | ADRBK2 | 0.38699042 |
| 93 | CAMK2D | 0.38257924 |
| 94 | RPS6KA3 | 0.38124962 |
| 95 | PRKCA | 0.34069742 |
| 96 | AKT3 | 0.34048986 |
| 97 | MAPK4 | 0.31794480 |
| 98 | ADRBK1 | 0.31509330 |
| 99 | CSNK1D | 0.29930355 |
| 100 | PRKCI | 0.29327070 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 4.89908225 |
| 2 | Nicotine addiction_Homo sapiens_hsa05033 | 4.33126167 |
| 3 | GABAergic synapse_Homo sapiens_hsa04727 | 3.11512320 |
| 4 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.82228530 |
| 5 | Morphine addiction_Homo sapiens_hsa05032 | 2.73820529 |
| 6 | Circadian entrainment_Homo sapiens_hsa04713 | 2.66884012 |
| 7 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.50392232 |
| 8 | Long-term potentiation_Homo sapiens_hsa04720 | 2.48253051 |
| 9 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.38060018 |
| 10 | Insulin secretion_Homo sapiens_hsa04911 | 2.34600753 |
| 11 | Dopaminergic synapse_Homo sapiens_hsa04728 | 2.18253755 |
| 12 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 2.08859058 |
| 13 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 2.08758318 |
| 14 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 2.07868005 |
| 15 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.93742336 |
| 16 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.89650511 |
| 17 | Salivary secretion_Homo sapiens_hsa04970 | 1.88984145 |
| 18 | Cocaine addiction_Homo sapiens_hsa05030 | 1.87388310 |
| 19 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.86193189 |
| 20 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.84481400 |
| 21 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.76405397 |
| 22 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.74743964 |
| 23 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.68296846 |
| 24 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.57828230 |
| 25 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.52909357 |
| 26 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.40908717 |
| 27 | Taste transduction_Homo sapiens_hsa04742 | 1.35790053 |
| 28 | Long-term depression_Homo sapiens_hsa04730 | 1.34362407 |
| 29 | Olfactory transduction_Homo sapiens_hsa04740 | 1.28094815 |
| 30 | Phototransduction_Homo sapiens_hsa04744 | 1.27100459 |
| 31 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.22740961 |
| 32 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.21398281 |
| 33 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.21227285 |
| 34 | Renin secretion_Homo sapiens_hsa04924 | 1.12033016 |
| 35 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.11057199 |
| 36 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.10085056 |
| 37 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.02455015 |
| 38 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.01363730 |
| 39 | Glioma_Homo sapiens_hsa05214 | 0.96438176 |
| 40 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.95452787 |
| 41 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.93085216 |
| 42 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.91849658 |
| 43 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.90862210 |
| 44 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.89103429 |
| 45 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.85790853 |
| 46 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.85297237 |
| 47 | Gap junction_Homo sapiens_hsa04540 | 0.82484983 |
| 48 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.82048734 |
| 49 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.81837884 |
| 50 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.78835613 |
| 51 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.76788149 |
| 52 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.74899096 |
| 53 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.71958021 |
| 54 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.69141570 |
| 55 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.66196344 |
| 56 | Axon guidance_Homo sapiens_hsa04360 | 0.65111696 |
| 57 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.64941736 |
| 58 | Melanogenesis_Homo sapiens_hsa04916 | 0.62847934 |
| 59 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.61941090 |
| 60 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.61739950 |
| 61 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.60225045 |
| 62 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.60144642 |
| 63 | Endocytosis_Homo sapiens_hsa04144 | 0.56845397 |
| 64 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.56654919 |
| 65 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.56282749 |
| 66 | Alzheimers disease_Homo sapiens_hsa05010 | 0.55461431 |
| 67 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.55298334 |
| 68 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.54727657 |
| 69 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.53965838 |
| 70 | Lysosome_Homo sapiens_hsa04142 | 0.52962543 |
| 71 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.49996488 |
| 72 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.48884591 |
| 73 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.47449416 |
| 74 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.46981100 |
| 75 | Prion diseases_Homo sapiens_hsa05020 | 0.44935156 |
| 76 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.44803720 |
| 77 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.44396091 |
| 78 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.41699002 |
| 79 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.41421300 |
| 80 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.41420083 |
| 81 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.40161039 |
| 82 | Phagosome_Homo sapiens_hsa04145 | 0.39490602 |
| 83 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.39477134 |
| 84 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.39164084 |
| 85 | Parkinsons disease_Homo sapiens_hsa05012 | 0.33765982 |
| 86 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.32488826 |
| 87 | Salmonella infection_Homo sapiens_hsa05132 | 0.32378360 |
| 88 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.31815892 |
| 89 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.29279419 |
| 90 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.28437168 |
| 91 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.27766612 |
| 92 | Shigellosis_Homo sapiens_hsa05131 | 0.26096005 |
| 93 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.23791370 |
| 94 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.23592396 |
| 95 | Sulfur relay system_Homo sapiens_hsa04122 | 0.21053208 |
| 96 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.17467598 |
| 97 | Alcoholism_Homo sapiens_hsa05034 | 0.17106643 |
| 98 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.15526159 |
| 99 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.14639458 |
| 100 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.14055704 |

