Rank | Gene Set | Z-score |
---|---|---|
1 | modulation by symbiont of host defense response (GO:0052031) | 6.46164046 |
2 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 6.46164046 |
3 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 6.46164046 |
4 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 6.46164046 |
5 | modulation by symbiont of host immune response (GO:0052553) | 6.46164046 |
6 | positive regulation by symbiont of host defense response (GO:0052509) | 6.46164046 |
7 | microglial cell activation (GO:0001774) | 6.18648751 |
8 | regulation of interferon-beta biosynthetic process (GO:0045357) | 6.16574139 |
9 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.76107324 |
10 | macrophage activation involved in immune response (GO:0002281) | 5.62561858 |
11 | neutrophil activation involved in immune response (GO:0002283) | 5.07316586 |
12 | positive regulation of interferon-alpha production (GO:0032727) | 5.00960314 |
13 | macrophage activation (GO:0042116) | 4.82677388 |
14 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 4.81213275 |
15 | regulation of interferon-alpha production (GO:0032647) | 4.74980571 |
16 | response to peptidoglycan (GO:0032494) | 4.70939457 |
17 | negative regulation of granulocyte differentiation (GO:0030853) | 4.67887146 |
18 | immunoglobulin mediated immune response (GO:0016064) | 4.63151376 |
19 | positive regulation of antigen processing and presentation (GO:0002579) | 4.44653851 |
20 | regulation of mononuclear cell migration (GO:0071675) | 4.37648509 |
21 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 4.29240780 |
22 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 4.28215424 |
23 | regulation of hypersensitivity (GO:0002883) | 4.28059268 |
24 | * complement activation, classical pathway (GO:0006958) | 4.25509304 |
25 | regulation of macrophage chemotaxis (GO:0010758) | 4.23052021 |
26 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 4.15933504 |
27 | respiratory burst (GO:0045730) | 4.13257567 |
28 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.08305123 |
29 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 4.07870822 |
30 | response to host immune response (GO:0052572) | 4.07870822 |
31 | production of molecular mediator involved in inflammatory response (GO:0002532) | 4.05680218 |
32 | pinocytosis (GO:0006907) | 3.94510438 |
33 | myeloid cell activation involved in immune response (GO:0002275) | 3.92756423 |
34 | * complement activation (GO:0006956) | 3.92237460 |
35 | positive regulation of monocyte chemotaxis (GO:0090026) | 3.83577391 |
36 | positive regulation of cellular amide metabolic process (GO:0034250) | 3.83070786 |
37 | regulation of apoptotic cell clearance (GO:2000425) | 3.82155205 |
38 | adhesion of symbiont to host cell (GO:0044650) | 3.82057277 |
39 | virion attachment to host cell (GO:0019062) | 3.82057277 |
40 | response to host (GO:0075136) | 3.77776850 |
41 | response to host defenses (GO:0052200) | 3.77776850 |
42 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.77776850 |
43 | cellular extravasation (GO:0045123) | 3.76222176 |
44 | regulation of antigen processing and presentation (GO:0002577) | 3.74669508 |
45 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 3.69001909 |
46 | positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:0061081 | 3.59268332 |
47 | positive regulation of chemokine secretion (GO:0090197) | 3.51800805 |
48 | adhesion of symbiont to host (GO:0044406) | 3.45607117 |
49 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.45195225 |
50 | positive regulation of interferon-beta production (GO:0032728) | 3.44735985 |
51 | phagocytosis, engulfment (GO:0006911) | 3.41621970 |
52 | I-kappaB phosphorylation (GO:0007252) | 3.41156194 |
53 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 3.40460792 |
54 | lymphocyte chemotaxis (GO:0048247) | 3.39879567 |
55 | glycolipid catabolic process (GO:0019377) | 3.39690758 |
56 | purinergic nucleotide receptor signaling pathway (GO:0035590) | 3.38134067 |
57 | regulation of interleukin-8 biosynthetic process (GO:0045414) | 3.37397170 |
58 | lipoxygenase pathway (GO:0019372) | 3.36587496 |
59 | detection of molecule of bacterial origin (GO:0032490) | 3.34726481 |
60 | adenosine receptor signaling pathway (GO:0001973) | 3.34692828 |
61 | hyaluronan catabolic process (GO:0030214) | 3.31291765 |
62 | granulocyte activation (GO:0036230) | 3.29282137 |
63 | mannose metabolic process (GO:0006013) | 3.28887422 |
64 | detection of external biotic stimulus (GO:0098581) | 3.26335229 |
65 | positive regulation of interferon-gamma biosynthetic process (GO:0045078) | 3.26259928 |
66 | response to muramyl dipeptide (GO:0032495) | 3.22539274 |
67 | regulation of monocyte chemotaxis (GO:0090025) | 3.21577974 |
68 | neutrophil activation (GO:0042119) | 3.20564158 |
69 | positive regulation of B cell differentiation (GO:0045579) | 3.20417245 |
70 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 3.20355230 |
71 | positive regulation of macrophage cytokine production (GO:0060907) | 3.20142146 |
72 | detection of other organism (GO:0098543) | 3.19562211 |
73 | apoptotic cell clearance (GO:0043277) | 3.19499981 |
74 | negative regulation of interleukin-6 production (GO:0032715) | 3.18241582 |
75 | myeloid leukocyte activation (GO:0002274) | 3.17376827 |
76 | positive regulation of mast cell activation (GO:0033005) | 3.16577425 |
77 | amino sugar catabolic process (GO:0046348) | 3.15836815 |
78 | B cell mediated immunity (GO:0019724) | 3.14868945 |
79 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 3.13643841 |
80 | detection of bacterium (GO:0016045) | 3.10407483 |
81 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 3.09605131 |
82 | positive regulation of mast cell degranulation (GO:0043306) | 3.09605131 |
83 | * protein activation cascade (GO:0072376) | 3.07855370 |
84 | regulation of mast cell degranulation (GO:0043304) | 3.07513612 |
85 | eosinophil migration (GO:0072677) | 3.05930976 |
86 | positive regulation of phagocytosis (GO:0050766) | 3.04949527 |
87 | angiotensin maturation (GO:0002003) | 3.03809735 |
88 | G-protein coupled purinergic receptor signaling pathway (GO:0035588) | 3.03526021 |
89 | cellular response to thyroid hormone stimulus (GO:0097067) | 3.02708986 |
90 | regulation of mast cell activation involved in immune response (GO:0033006) | 3.00509168 |
91 | complement activation, alternative pathway (GO:0006957) | 2.99663639 |
92 | regulation of acute inflammatory response to antigenic stimulus (GO:0002864) | 2.98793144 |
93 | negative regulation of interleukin-17 production (GO:0032700) | 2.97174534 |
94 | eosinophil chemotaxis (GO:0048245) | 2.97050353 |
95 | glycosphingolipid catabolic process (GO:0046479) | 2.96404033 |
96 | positive regulation of lymphocyte migration (GO:2000403) | 2.94603803 |
97 | antigen processing and presentation of endogenous antigen (GO:0019883) | 2.91670233 |
98 | positive regulation of leukocyte degranulation (GO:0043302) | 2.91245582 |
99 | barbed-end actin filament capping (GO:0051016) | 2.91187428 |
100 | germinal center formation (GO:0002467) | 2.89847354 |
101 | ceramide catabolic process (GO:0046514) | 2.89368912 |
102 | cellular response to interferon-gamma (GO:0071346) | 2.88457835 |
103 | T-helper 1 type immune response (GO:0042088) | 2.88240438 |
104 | regulation of mast cell activation (GO:0033003) | 2.88040484 |
105 | peptide catabolic process (GO:0043171) | 2.87523546 |
106 | mast cell activation (GO:0045576) | 2.87132710 |
107 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.85202977 |
108 | myeloid dendritic cell differentiation (GO:0043011) | 2.84780482 |
109 | neutrophil chemotaxis (GO:0030593) | 2.83539326 |
110 | adaptive immune response based on somatic recombination of immune receptors built from immunoglobuli | 2.82433435 |
111 | detection of biotic stimulus (GO:0009595) | 2.81711672 |
112 | keratan sulfate catabolic process (GO:0042340) | 2.81555581 |
113 | positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557) | 2.81514196 |
114 | positive regulation of smooth muscle cell migration (GO:0014911) | 2.80548399 |
115 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 2.80520828 |
116 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 2.80405142 |
117 | regulation of cholesterol storage (GO:0010885) | 2.79374765 |
118 | regulation of inflammatory response to antigenic stimulus (GO:0002861) | 2.78508919 |
119 | positive regulation of gamma-delta T cell activation (GO:0046645) | 2.78092314 |
120 | positive regulation of T cell migration (GO:2000406) | 2.77500696 |
121 | purinergic receptor signaling pathway (GO:0035587) | 2.77266743 |
122 | neutrophil migration (GO:1990266) | 2.75400733 |
123 | response to interferon-gamma (GO:0034341) | 2.75066538 |
124 | negative regulation of interleukin-12 production (GO:0032695) | 2.74971271 |
125 | positive regulation of type 2 immune response (GO:0002830) | 2.74458217 |
126 | cellular response to ethanol (GO:0071361) | 2.74418393 |
127 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 2.74024956 |
128 | negative regulation of mast cell activation (GO:0033004) | 2.73984999 |
129 | negative regulation of cell killing (GO:0031342) | 2.73219811 |
130 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 2.73219811 |
131 | regulation of leukocyte degranulation (GO:0043300) | 2.71726569 |
132 | myeloid dendritic cell activation (GO:0001773) | 2.71368756 |
133 | regulation of complement activation (GO:0030449) | 2.70922501 |
134 | oligosaccharide catabolic process (GO:0009313) | 2.70734481 |
135 | positive regulation of cholesterol efflux (GO:0010875) | 2.70678129 |
136 | fat-soluble vitamin biosynthetic process (GO:0042362) | 2.70632758 |
137 | surfactant homeostasis (GO:0043129) | 2.69742883 |
138 | positive regulation of chemokine production (GO:0032722) | 2.69496060 |
139 | low-density lipoprotein particle remodeling (GO:0034374) | 2.67415569 |
140 | membrane invagination (GO:0010324) | 2.66999958 |
141 | regulation of chemokine secretion (GO:0090196) | 2.66031362 |
142 | phospholipid efflux (GO:0033700) | 2.65568380 |
143 | response to thyroid hormone (GO:0097066) | 2.63619434 |
144 | N-acetylneuraminate metabolic process (GO:0006054) | 2.62206605 |
145 | cellular response to type I interferon (GO:0071357) | 2.61511245 |
146 | type I interferon signaling pathway (GO:0060337) | 2.61511245 |
147 | regulation of cholesterol esterification (GO:0010872) | 2.60478456 |
148 | response to type I interferon (GO:0034340) | 2.59296439 |
149 | regulation of protein activation cascade (GO:2000257) | 2.55501613 |
150 | hydrogen peroxide biosynthetic process (GO:0050665) | 2.52034544 |
151 | regulation of phagocytosis (GO:0050764) | 2.50103043 |
152 | * humoral immune response (GO:0006959) | 2.45988360 |
153 | positive regulation of acute inflammatory response (GO:0002675) | 2.43439829 |
154 | monocyte chemotaxis (GO:0002548) | 2.43133359 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 7.17646286 |
2 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 6.94254236 |
3 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.45894073 |
4 | * IRF8_27001747_Chip-Seq_BMDM_Mouse | 5.19120400 |
5 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 4.66561280 |
6 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.80744299 |
7 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 3.54018356 |
8 | * NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 3.09025247 |
9 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.04078185 |
10 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.02863881 |
11 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.85279784 |
12 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.41078555 |
13 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.38812459 |
14 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.37474744 |
15 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.36809091 |
16 | * SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.30873568 |
17 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.19552960 |
18 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 2.16142516 |
19 | SPI1_23127762_ChIP-Seq_K562_Human | 2.14708820 |
20 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.13242026 |
21 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 2.12937563 |
22 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 2.12534004 |
23 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 2.10849660 |
24 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.06675373 |
25 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 2.03798255 |
26 | * SPI1_23547873_ChIP-Seq_NB4_Human | 2.01094885 |
27 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.94264195 |
28 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.84880627 |
29 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.84482864 |
30 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.76110964 |
31 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.75656968 |
32 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.74181106 |
33 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.73431712 |
34 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.71814489 |
35 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.70990339 |
36 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.64569183 |
37 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.60780732 |
38 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.59782932 |
39 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.45078250 |
40 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.40115095 |
41 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.39364482 |
42 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.38955472 |
43 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.38111256 |
44 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.38093521 |
45 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.35221456 |
46 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.34525448 |
47 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.32630252 |
48 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.32628896 |
49 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.32287747 |
50 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.31578673 |
51 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.31037796 |
52 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.29192927 |
53 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.28646185 |
54 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.28019338 |
55 | MAF_26560356_Chip-Seq_TH1_Human | 1.27667704 |
56 | MYB_26560356_Chip-Seq_TH2_Human | 1.26176663 |
57 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.24846768 |
58 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.24739386 |
59 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.24517262 |
60 | GATA1_22025678_ChIP-Seq_K562_Human | 1.23156152 |
61 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.21888241 |
62 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.21243678 |
63 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 1.17656522 |
64 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.13681374 |
65 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.11756264 |
66 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.10267305 |
67 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.08794612 |
68 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.07797345 |
69 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.06952256 |
70 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.06347963 |
71 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.06104878 |
72 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.05388201 |
73 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.04451995 |
74 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.04410828 |
75 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.04308142 |
76 | GATA1_19941826_ChIP-Seq_K562_Human | 1.04104106 |
77 | SPI1_20517297_ChIP-Seq_HL60_Human | 1.03062837 |
78 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.01832889 |
79 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.01435077 |
80 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.00870031 |
81 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.99766475 |
82 | KDM2B_26808549_Chip-Seq_K562_Human | 0.99272743 |
83 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.98897516 |
84 | * DROSHA_22980978_ChIP-Seq_HELA_Human | 0.98324215 |
85 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.98232226 |
86 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 0.96805821 |
87 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 0.96480622 |
88 | GATA2_19941826_ChIP-Seq_K562_Human | 0.96273883 |
89 | * PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.95760133 |
90 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.95563475 |
91 | GATA3_26560356_Chip-Seq_TH2_Human | 0.95051715 |
92 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 0.93794122 |
93 | MYB_26560356_Chip-Seq_TH1_Human | 0.93743306 |
94 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 0.93019358 |
95 | RACK7_27058665_Chip-Seq_MCF-7_Human | 0.92517765 |
96 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.92368028 |
97 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.92130883 |
98 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.90555974 |
99 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.90398383 |
100 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 0.89734429 |
101 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 0.89734429 |
102 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 0.88517241 |
103 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.87365035 |
104 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.86251407 |
105 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.84834915 |
106 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 0.83498984 |
107 | * EGR1_19032775_ChIP-ChIP_M12_Human | 0.82766873 |
108 | GATA3_27048872_Chip-Seq_THYMUS_Human | 0.82533128 |
109 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.81906781 |
110 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.80349853 |
111 | UTX_26944678_Chip-Seq_JUKART_Human | 0.78896477 |
112 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.76381725 |
113 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.76114271 |
114 | CJUN_26792858_Chip-Seq_BT549_Human | 0.73954441 |
115 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.73812417 |
116 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.73751774 |
117 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 0.71564193 |
118 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.71428108 |
119 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.70550660 |
120 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.69828533 |
121 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.68619010 |
122 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 0.67385630 |
123 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.67317474 |
124 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.67317474 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0005058_abnormal_lysosome_morphology | 5.11772091 |
2 | MP0001835_abnormal_antigen_presentation | 4.48277381 |
3 | MP0006082_CNS_inflammation | 3.71853214 |
4 | MP0003436_decreased_susceptibility_to | 3.68187080 |
5 | MP0009840_abnormal_foam_cell | 3.48972717 |
6 | MP0002148_abnormal_hypersensitivity_rea | 3.44272513 |
7 | MP0003191_abnormal_cellular_cholesterol | 3.38114577 |
8 | MP0002419_abnormal_innate_immunity | 3.22430561 |
9 | MP0003172_abnormal_lysosome_physiology | 2.95188316 |
10 | MP0005000_abnormal_immune_tolerance | 2.85423436 |
11 | MP0003303_peritoneal_inflammation | 2.82418051 |
12 | MP0002139_abnormal_hepatobiliary_system | 2.73914815 |
13 | MP0005025_abnormal_response_to | 2.55898752 |
14 | MP0003690_abnormal_glial_cell | 2.55667975 |
15 | MP0009785_altered_susceptibility_to | 2.50001611 |
16 | MP0005387_immune_system_phenotype | 2.48158240 |
17 | MP0001790_abnormal_immune_system | 2.48158240 |
18 | MP0003724_increased_susceptibility_to | 2.44324708 |
19 | MP0005464_abnormal_platelet_physiology | 2.40932596 |
20 | MP0005671_abnormal_response_to | 2.40632745 |
21 | MP0002452_abnormal_antigen_presenting | 2.39125208 |
22 | MP0003075_altered_response_to | 2.35269853 |
23 | MP0001533_abnormal_skeleton_physiology | 2.31745956 |
24 | MP0001800_abnormal_humoral_immune | 2.25712571 |
25 | MP0005360_urolithiasis | 2.14078230 |
26 | MP0002723_abnormal_immune_serum | 2.13862978 |
27 | MP0000685_abnormal_immune_system | 2.13210898 |
28 | MP0004510_myositis | 2.06094419 |
29 | MP0000343_altered_response_to | 2.05384878 |
30 | MP0001819_abnormal_immune_cell | 1.90522175 |
31 | MP0002420_abnormal_adaptive_immunity | 1.88754369 |
32 | MP0003329_amyloid_beta_deposits | 1.85805121 |
33 | MP0000604_amyloidosis | 1.84038881 |
34 | MP0002405_respiratory_system_inflammati | 1.78962310 |
35 | MP0001845_abnormal_inflammatory_respons | 1.69433471 |
36 | MP0008469_abnormal_protein_level | 1.68169418 |
37 | MP0005310_abnormal_salivary_gland | 1.64849009 |
38 | MP0008438_abnormal_cutaneous_collagen | 1.63579306 |
39 | MP0005365_abnormal_bile_salt | 1.61215604 |
40 | MP0005166_decreased_susceptibility_to | 1.59675175 |
41 | MP0001853_heart_inflammation | 1.58165638 |
42 | MP0003300_gastrointestinal_ulcer | 1.52401991 |
43 | MP0002998_abnormal_bone_remodeling | 1.47476380 |
44 | MP0004947_skin_inflammation | 1.43394857 |
45 | MP0009764_decreased_sensitivity_to | 1.42662657 |
46 | MP0009333_abnormal_splenocyte_physiolog | 1.38512872 |
47 | MP0003448_altered_tumor_morphology | 1.34751166 |
48 | MP0000465_gastrointestinal_hemorrhage | 1.30084499 |
49 | MP0000716_abnormal_immune_system | 1.29052613 |
50 | MP0005167_abnormal_blood-brain_barrier | 1.27581135 |
51 | MP0010155_abnormal_intestine_physiology | 1.25267270 |
52 | MP0004883_abnormal_blood_vessel | 1.23351306 |
53 | MP0000689_abnormal_spleen_morphology | 1.22790772 |
54 | MP0003828_pulmonary_edema | 1.21551679 |
55 | MP0002277_abnormal_respiratory_mucosa | 1.16818625 |
56 | MP0004019_abnormal_vitamin_homeostasis | 1.15475311 |
57 | MP0009278_abnormal_bone_marrow | 1.13044235 |
58 | MP0003183_abnormal_peptide_metabolism | 1.11519717 |
59 | MP0005451_abnormal_body_composition | 1.10429422 |
60 | MP0002398_abnormal_bone_marrow | 1.08923177 |
61 | MP0005390_skeleton_phenotype | 1.07572463 |
62 | MP0001851_eye_inflammation | 1.06185353 |
63 | MP0003195_calcinosis | 1.04449012 |
64 | MP0005164_abnormal_response_to | 1.03693793 |
65 | MP0000249_abnormal_blood_vessel | 1.03631837 |
66 | MP0001958_emphysema | 1.03601462 |
67 | MP0003453_abnormal_keratinocyte_physiol | 1.02965379 |
68 | MP0002429_abnormal_blood_cell | 1.02499637 |
69 | MP0009763_increased_sensitivity_to | 1.00754910 |
70 | MP0003279_aneurysm | 0.98668911 |
71 | MP0004782_abnormal_surfactant_physiolog | 0.98230007 |
72 | MP0002166_altered_tumor_susceptibility | 0.97300993 |
73 | MP0003879_abnormal_hair_cell | 0.97066601 |
74 | MP0003091_abnormal_cell_migration | 0.96649111 |
75 | MP0003806_abnormal_nucleotide_metabolis | 0.96522346 |
76 | MP0000858_altered_metastatic_potential | 0.95687567 |
77 | MP0002722_abnormal_immune_system | 0.95005366 |
78 | MP0002090_abnormal_vision | 0.93882962 |
79 | MP0010307_abnormal_tumor_latency | 0.93844059 |
80 | MP0003566_abnormal_cell_adhesion | 0.92554519 |
81 | MP0002933_joint_inflammation | 0.92114236 |
82 | MP0005595_abnormal_vascular_smooth | 0.92000457 |
83 | MP0003045_fibrosis | 0.89947192 |
84 | MP0000920_abnormal_myelination | 0.89716527 |
85 | MP0001663_abnormal_digestive_system | 0.86882036 |
86 | MP0005670_abnormal_white_adipose | 0.86520719 |
87 | MP0003705_abnormal_hypodermis_morpholog | 0.86132040 |
88 | MP0003866_abnormal_defecation | 0.84079391 |
89 | MP0005165_increased_susceptibility_to | 0.83287115 |
90 | MP0002971_abnormal_brown_adipose | 0.83164754 |
91 | MP0000767_abnormal_smooth_muscle | 0.83084841 |
92 | MP0002254_reproductive_system_inflammat | 0.83061927 |
93 | MP0005085_abnormal_gallbladder_physiolo | 0.82981787 |
94 | MP0008004_abnormal_stomach_pH | 0.81161750 |
95 | MP0000609_abnormal_liver_physiology | 0.80810884 |
96 | MP0001666_abnormal_nutrient_absorption | 0.78601115 |
97 | MP0002006_tumorigenesis | 0.77600968 |
98 | MP0009643_abnormal_urine_homeostasis | 0.76163229 |
99 | MP0008260_abnormal_autophagy | 0.75095563 |
100 | MP0005397_hematopoietic_system_phenotyp | 0.74678675 |
101 | MP0001545_abnormal_hematopoietic_system | 0.74678675 |
102 | MP0001915_intracranial_hemorrhage | 0.74255887 |
103 | MP0003795_abnormal_bone_structure | 0.72397787 |
104 | MP0004858_abnormal_nervous_system | 0.71863141 |
105 | MP0002136_abnormal_kidney_physiology | 0.71042244 |
106 | MP0005257_abnormal_intraocular_pressure | 0.69715064 |
107 | MP0002138_abnormal_hepatobiliary_system | 0.69383040 |
108 | MP0002118_abnormal_lipid_homeostasis | 0.69025499 |
109 | MP0003011_delayed_dark_adaptation | 0.68038096 |
110 | MP0008873_increased_physiological_sensi | 0.67966260 |
111 | MP0004130_abnormal_muscle_cell | 0.67353806 |
112 | MP0000569_abnormal_digit_pigmentation | 0.66734854 |
113 | MP0009115_abnormal_fat_cell | 0.66324603 |
114 | MP0002896_abnormal_bone_mineralization | 0.64686362 |
115 | MP0003656_abnormal_erythrocyte_physiolo | 0.61843394 |
116 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.59868926 |
117 | MP0010329_abnormal_lipoprotein_level | 0.58565502 |
118 | MP0000371_diluted_coat_color | 0.58200750 |
119 | MP0003633_abnormal_nervous_system | 0.57396280 |
120 | MP0005076_abnormal_cell_differentiation | 0.56867314 |
121 | MP0005023_abnormal_wound_healing | 0.55906581 |
122 | MP0003252_abnormal_bile_duct | 0.54790196 |
123 | MP0003634_abnormal_glial_cell | 0.54630230 |
124 | MP0001542_abnormal_bone_strength | 0.51752650 |
125 | MP0000015_abnormal_ear_pigmentation | 0.51650523 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * Systemic lupus erythematosus (HP:0002725) | 9.26294555 |
2 | * Glomerulonephritis (HP:0000099) | 6.87268307 |
3 | Recurrent abscess formation (HP:0002722) | 6.36221596 |
4 | Increased cerebral lipofuscin (HP:0011813) | 5.98437453 |
5 | Recurrent bacterial skin infections (HP:0005406) | 5.82830067 |
6 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 5.63402025 |
7 | Vacuolated lymphocytes (HP:0001922) | 5.56805076 |
8 | * Complement deficiency (HP:0004431) | 5.45519397 |
9 | Eczematoid dermatitis (HP:0000976) | 5.25768580 |
10 | Abnormality of glycolipid metabolism (HP:0010969) | 5.21265724 |
11 | Abnormality of liposaccharide metabolism (HP:0010968) | 5.21265724 |
12 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 5.21265724 |
13 | Dysostosis multiplex (HP:0000943) | 5.19735542 |
14 | * Abnormality of complement system (HP:0005339) | 5.16661513 |
15 | Recurrent gram-negative bacterial infections (HP:0005420) | 4.64055492 |
16 | Axonal loss (HP:0003447) | 4.27524647 |
17 | Disinhibition (HP:0000734) | 4.21959759 |
18 | Mucopolysacchariduria (HP:0008155) | 3.88384020 |
19 | Urinary glycosaminoglycan excretion (HP:0003541) | 3.88384020 |
20 | * Nephritis (HP:0000123) | 3.77300725 |
21 | Abnormality of macrophages (HP:0004311) | 3.73704817 |
22 | Abnormality of polysaccharide metabolism (HP:0011012) | 3.66982672 |
23 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 3.66982672 |
24 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 3.66982672 |
25 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 3.64618611 |
26 | Agnosia (HP:0010524) | 3.43263309 |
27 | Recurrent skin infections (HP:0001581) | 3.27968448 |
28 | Malnutrition (HP:0004395) | 3.16025578 |
29 | Thick nail (HP:0001805) | 3.16005914 |
30 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 3.14829239 |
31 | Upper motor neuron abnormality (HP:0002127) | 3.12916037 |
32 | Mediastinal lymphadenopathy (HP:0100721) | 3.08672882 |
33 | Gingivitis (HP:0000230) | 2.99456576 |
34 | Myositis (HP:0100614) | 2.90282320 |
35 | Spontaneous hematomas (HP:0007420) | 2.86198743 |
36 | Pustule (HP:0200039) | 2.83818638 |
37 | Arterial tortuosity (HP:0005116) | 2.83589200 |
38 | Mutism (HP:0002300) | 2.82356521 |
39 | Retinal atrophy (HP:0001105) | 2.80332561 |
40 | Obstructive lung disease (HP:0006536) | 2.76841364 |
41 | Chronic obstructive pulmonary disease (HP:0006510) | 2.76841364 |
42 | Orchitis (HP:0100796) | 2.71978647 |
43 | Hematochezia (HP:0002573) | 2.70485941 |
44 | Loss of speech (HP:0002371) | 2.69188749 |
45 | Hepatosplenomegaly (HP:0001433) | 2.67191318 |
46 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.63334659 |
47 | Pathologic fracture (HP:0002756) | 2.61891845 |
48 | Myocardial infarction (HP:0001658) | 2.59240250 |
49 | Basal ganglia calcification (HP:0002135) | 2.56879547 |
50 | Asymmetric septal hypertrophy (HP:0001670) | 2.52873617 |
51 | Vascular tortuosity (HP:0004948) | 2.45503053 |
52 | Progressive visual loss (HP:0000529) | 2.44874745 |
53 | Periodontitis (HP:0000704) | 2.42415164 |
54 | Prostate neoplasm (HP:0100787) | 2.41550087 |
55 | Recurrent fungal infections (HP:0002841) | 2.41478361 |
56 | J-shaped sella turcica (HP:0002680) | 2.41190581 |
57 | Hemoptysis (HP:0002105) | 2.40596733 |
58 | Cerebral aneurysm (HP:0004944) | 2.40492952 |
59 | Cellulitis (HP:0100658) | 2.39262954 |
60 | Autoimmune thrombocytopenia (HP:0001973) | 2.38327568 |
61 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.37095652 |
62 | Osteolytic defects of the hand bones (HP:0009699) | 2.37095652 |
63 | Recurrent viral infections (HP:0004429) | 2.36338302 |
64 | Cerebral inclusion bodies (HP:0100314) | 2.35447705 |
65 | Colitis (HP:0002583) | 2.32209196 |
66 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 2.31470760 |
67 | Progressive neurologic deterioration (HP:0002344) | 2.30794436 |
68 | Petechiae (HP:0000967) | 2.30215024 |
69 | Nuclear cataract (HP:0100018) | 2.28773619 |
70 | Joint hemorrhage (HP:0005261) | 2.25863136 |
71 | Optic neuritis (HP:0100653) | 2.22966672 |
72 | Retrobulbar optic neuritis (HP:0100654) | 2.22966672 |
73 | Xanthomatosis (HP:0000991) | 2.22514252 |
74 | Inappropriate behavior (HP:0000719) | 2.21902192 |
75 | Amyloidosis (HP:0011034) | 2.19837729 |
76 | Thoracic kyphosis (HP:0002942) | 2.18087024 |
77 | Neoplasm of head and neck (HP:0012288) | 2.17764206 |
78 | Esophageal neoplasm (HP:0100751) | 2.17764206 |
79 | Stomatitis (HP:0010280) | 2.16492836 |
80 | Neurofibrillary tangles (HP:0002185) | 2.16110962 |
81 | Peripheral demyelination (HP:0011096) | 2.14701452 |
82 | Abnormality of the nasal mucosa (HP:0000433) | 2.13365543 |
83 | Recurrent cutaneous fungal infections (HP:0011370) | 2.12163869 |
84 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.12163869 |
85 | Premature loss of primary teeth (HP:0006323) | 2.11980208 |
86 | Abnormality of the lumbar spine (HP:0100712) | 2.11948266 |
87 | Osteomyelitis (HP:0002754) | 2.08709325 |
88 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 2.08552484 |
89 | Apathy (HP:0000741) | 2.05145583 |
90 | Urticaria (HP:0001025) | 2.04625614 |
91 | Neuronal loss in central nervous system (HP:0002529) | 2.02450401 |
92 | Spondylolisthesis (HP:0003302) | 2.01659919 |
93 | Hemorrhage of the eye (HP:0011885) | 2.00990663 |
94 | Abnormality of iron homeostasis (HP:0011031) | 2.00626445 |
95 | Bone pain (HP:0002653) | 1.99846812 |
96 | Diminished motivation (HP:0000745) | 1.98586113 |
97 | Segmental peripheral demyelination/remyelination (HP:0003481) | 1.98582452 |
98 | Interstitial pulmonary disease (HP:0006530) | 1.96530927 |
99 | Personality changes (HP:0000751) | 1.96342628 |
100 | Pulmonary infiltrates (HP:0002113) | 1.95484893 |
101 | Increased CSF protein (HP:0002922) | 1.95025017 |
102 | Inflammation of the large intestine (HP:0002037) | 1.92408050 |
103 | Vasculitis (HP:0002633) | 1.89419152 |
104 | Increased serum ferritin (HP:0003281) | 1.88621867 |
105 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 1.87895001 |
106 | Abnormality of the periventricular white matter (HP:0002518) | 1.87015215 |
107 | Arterial thrombosis (HP:0004420) | 1.86341993 |
108 | Leukocytosis (HP:0001974) | 1.84339420 |
109 | Recurrent pneumonia (HP:0006532) | 1.84231807 |
110 | Conjunctival telangiectasia (HP:0000524) | 1.83729324 |
111 | Restrictive lung disease (HP:0002091) | 1.81010805 |
112 | Disproportionate tall stature (HP:0001519) | 1.80726583 |
113 | Meningitis (HP:0001287) | 1.80571506 |
114 | Decreased circulating renin level (HP:0003351) | 1.78964633 |
115 | Gastrointestinal stroma tumor (HP:0100723) | 1.78539618 |
116 | Dementia (HP:0000726) | 1.78322143 |
117 | Gastrointestinal inflammation (HP:0004386) | 1.74319343 |
118 | Pulmonary embolism (HP:0002204) | 1.73800078 |
119 | Chronic otitis media (HP:0000389) | 1.73722301 |
120 | Emphysema (HP:0002097) | 1.73492163 |
121 | Purpura (HP:0000979) | 1.73382975 |
122 | Joint stiffness (HP:0001387) | 1.72695558 |
123 | Vertebral compression fractures (HP:0002953) | 1.72553533 |
124 | Spinal muscular atrophy (HP:0007269) | 1.71817281 |
125 | Memory impairment (HP:0002354) | 1.71264177 |
126 | Bone cyst (HP:0012062) | 1.70620792 |
127 | Thin bony cortex (HP:0002753) | 1.67290758 |
128 | Polycythemia (HP:0001901) | 1.66722416 |
129 | Pulmonary hypertension (HP:0002092) | 1.64382953 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TGFBR2 | 5.32199844 |
2 | BLK | 5.04107301 |
3 | TYK2 | 3.54909069 |
4 | GRK7 | 3.33133437 |
5 | IRAK4 | 3.28119071 |
6 | RIPK4 | 3.21807279 |
7 | MAP3K14 | 2.98869342 |
8 | TBK1 | 2.88852133 |
9 | ERN1 | 2.57629568 |
10 | CSF1R | 2.37595030 |
11 | KIT | 2.26337794 |
12 | MAP4K1 | 2.19196282 |
13 | IRAK3 | 2.14880465 |
14 | DDR2 | 2.00846485 |
15 | CAMK1D | 1.93839984 |
16 | CDC42BPA | 1.88109310 |
17 | IKBKB | 1.87926073 |
18 | JAK1 | 1.87134315 |
19 | ZAP70 | 1.82226262 |
20 | NEK9 | 1.70514873 |
21 | EPHA3 | 1.69321502 |
22 | IKBKE | 1.67080987 |
23 | TXK | 1.66569843 |
24 | HCK | 1.61673964 |
25 | PRPF4B | 1.56716026 |
26 | CSK | 1.44410917 |
27 | EPHB1 | 1.41645905 |
28 | BTK | 1.37361648 |
29 | LYN | 1.37050568 |
30 | ACVR1B | 1.36772534 |
31 | STK10 | 1.34308345 |
32 | MAPK15 | 1.33596205 |
33 | SYK | 1.28397733 |
34 | CAMK1G | 1.26509206 |
35 | JAK2 | 1.23416285 |
36 | FES | 1.19366190 |
37 | CAMKK2 | 1.18966455 |
38 | MAP3K1 | 1.13597489 |
39 | LCK | 1.12385877 |
40 | CLK1 | 1.10269811 |
41 | ADRBK2 | 1.09363333 |
42 | PKN2 | 1.08390816 |
43 | BMPR2 | 1.05609635 |
44 | MOS | 1.05275628 |
45 | PAK4 | 1.03928316 |
46 | TAOK1 | 1.00215502 |
47 | TAOK2 | 0.99517187 |
48 | EPHB2 | 0.99050337 |
49 | NME2 | 0.98446587 |
50 | MAP2K3 | 0.98111102 |
51 | MATK | 0.96808874 |
52 | TEC | 0.95862419 |
53 | CAMKK1 | 0.93952353 |
54 | JAK3 | 0.92151883 |
55 | PDK2 | 0.91688585 |
56 | MST1R | 0.90566024 |
57 | ITK | 0.89747297 |
58 | PDGFRA | 0.89297258 |
59 | SCYL2 | 0.88813557 |
60 | CHUK | 0.88285314 |
61 | FGR | 0.87887331 |
62 | PRKG2 | 0.85675337 |
63 | TRIB3 | 0.84768209 |
64 | TAOK3 | 0.83176240 |
65 | EGFR | 0.76599139 |
66 | BMX | 0.73646266 |
67 | YES1 | 0.73008895 |
68 | MAPK12 | 0.72078669 |
69 | CDK6 | 0.69496472 |
70 | IGF1R | 0.66490930 |
71 | TESK1 | 0.66336432 |
72 | PIM2 | 0.66233393 |
73 | EIF2AK2 | 0.65724385 |
74 | DMPK | 0.65629479 |
75 | PRKCD | 0.63772064 |
76 | TNK2 | 0.61688744 |
77 | PTK6 | 0.61453403 |
78 | PIK3CG | 0.60863681 |
79 | MAPK7 | 0.59950392 |
80 | MAP3K13 | 0.59640345 |
81 | MARK2 | 0.57726058 |
82 | SIK2 | 0.57677267 |
83 | PRKAA2 | 0.57136234 |
84 | MAP3K3 | 0.57038142 |
85 | HIPK2 | 0.56002223 |
86 | MAPKAPK2 | 0.55520799 |
87 | ABL1 | 0.49584970 |
88 | SIK1 | 0.48725980 |
89 | GRK5 | 0.47982480 |
90 | PDK1 | 0.47438384 |
91 | TTN | 0.46932537 |
92 | IRAK2 | 0.46380250 |
93 | MAP3K6 | 0.46278849 |
94 | FYN | 0.44672103 |
95 | RIPK1 | 0.44655531 |
96 | MAP3K5 | 0.44291283 |
97 | TESK2 | 0.42866374 |
98 | RET | 0.42433526 |
99 | PRKD1 | 0.41789517 |
100 | FGFR4 | 0.41176585 |
101 | FGFR3 | 0.41146807 |
102 | FER | 0.40914316 |
103 | MYLK | 0.40227940 |
104 | MAP3K11 | 0.40093299 |
105 | ABL2 | 0.38958774 |
106 | PRKACG | 0.38460107 |
107 | PBK | 0.37388709 |
108 | PDPK1 | 0.37277939 |
109 | IRAK1 | 0.36319270 |
110 | PIM1 | 0.36114893 |
111 | MARK3 | 0.33641537 |
112 | ICK | 0.32466753 |
113 | CAMK2G | 0.32200677 |
114 | GSK3A | 0.31052991 |
115 | RPS6KA2 | 0.30870632 |
116 | INSR | 0.30412744 |
117 | MAPK4 | 0.29559199 |
118 | TRPM7 | 0.28126162 |
119 | PDGFRB | 0.26703562 |
120 | RPS6KA6 | 0.25375885 |
121 | CAMK4 | 0.24559754 |
122 | RPS6KA4 | 0.23840218 |
123 | SGK3 | 0.23642384 |
124 | PKN1 | 0.23625893 |
125 | SRC | 0.22098276 |
126 | RPS6KC1 | 0.18899629 |
127 | RPS6KL1 | 0.18899629 |
128 | MAPKAPK5 | 0.18278039 |
129 | PAK2 | 0.18223901 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * Staphylococcus aureus infection_Homo sapiens_hsa05150 | 5.87172896 |
2 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 4.11368426 |
3 | Other glycan degradation_Homo sapiens_hsa00511 | 3.83690267 |
4 | Lysosome_Homo sapiens_hsa04142 | 3.53910079 |
5 | Leishmaniasis_Homo sapiens_hsa05140 | 2.96222963 |
6 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.67214875 |
7 | * Pertussis_Homo sapiens_hsa05133 | 2.59066965 |
8 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.44582511 |
9 | * Complement and coagulation cascades_Homo sapiens_hsa04610 | 2.27493385 |
10 | Tuberculosis_Homo sapiens_hsa05152 | 2.10993765 |
11 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 2.06683187 |
12 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.98769123 |
13 | Legionellosis_Homo sapiens_hsa05134 | 1.95784446 |
14 | Malaria_Homo sapiens_hsa05144 | 1.87301815 |
15 | * Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.80093599 |
16 | Phagosome_Homo sapiens_hsa04145 | 1.79592858 |
17 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.77297291 |
18 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.69156974 |
19 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.63050089 |
20 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.55811569 |
21 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.55025301 |
22 | Measles_Homo sapiens_hsa05162 | 1.47347285 |
23 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.47012472 |
24 | Salmonella infection_Homo sapiens_hsa05132 | 1.46124463 |
25 | * Prion diseases_Homo sapiens_hsa05020 | 1.39776521 |
26 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.35301478 |
27 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.26190961 |
28 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.22725606 |
29 | Influenza A_Homo sapiens_hsa05164 | 1.22362153 |
30 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.17903457 |
31 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.16655514 |
32 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.14216056 |
33 | Histidine metabolism_Homo sapiens_hsa00340 | 1.12266650 |
34 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.10778611 |
35 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.09839196 |
36 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.05796333 |
37 | Asthma_Homo sapiens_hsa05310 | 1.02336308 |
38 | Apoptosis_Homo sapiens_hsa04210 | 1.01513653 |
39 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.01066267 |
40 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.00879555 |
41 | Allograft rejection_Homo sapiens_hsa05330 | 0.99674031 |
42 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.94987151 |
43 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.94213033 |
44 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.87090904 |
45 | Shigellosis_Homo sapiens_hsa05131 | 0.86629514 |
46 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.85829418 |
47 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.85393149 |
48 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.83986009 |
49 | Amoebiasis_Homo sapiens_hsa05146 | 0.83959110 |
50 | * Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.80307379 |
51 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.79605973 |
52 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.78820559 |
53 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.78321024 |
54 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.75511553 |
55 | Endocytosis_Homo sapiens_hsa04144 | 0.75334209 |
56 | Platelet activation_Homo sapiens_hsa04611 | 0.75083017 |
57 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.73393651 |
58 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.71285999 |
59 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.69703500 |
60 | Hepatitis B_Homo sapiens_hsa05161 | 0.69328505 |
61 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.69237151 |
62 | Galactose metabolism_Homo sapiens_hsa00052 | 0.68652777 |
63 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.68525962 |
64 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.68518690 |
65 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.64338817 |
66 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.63603266 |
67 | ABC transporters_Homo sapiens_hsa02010 | 0.63509314 |
68 | Hepatitis C_Homo sapiens_hsa05160 | 0.62425477 |
69 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.62308572 |
70 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.59960839 |
71 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.59811969 |
72 | Mineral absorption_Homo sapiens_hsa04978 | 0.58391458 |
73 | Viral myocarditis_Homo sapiens_hsa05416 | 0.56689609 |
74 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.56602147 |
75 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.53719945 |
76 | Bile secretion_Homo sapiens_hsa04976 | 0.49827050 |
77 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.47453372 |
78 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.46935869 |
79 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.45693851 |
80 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.45116896 |
81 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.45079187 |
82 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.44953213 |
83 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.43961695 |
84 | Renin secretion_Homo sapiens_hsa04924 | 0.43789858 |
85 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.43713632 |
86 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.43341928 |
87 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.42705523 |
88 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.40687162 |
89 | Retinol metabolism_Homo sapiens_hsa00830 | 0.39660446 |
90 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.39131980 |
91 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.37662488 |
92 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.37392208 |
93 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.36843944 |
94 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.36576238 |
95 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.36086877 |
96 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.36076104 |
97 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.33090759 |
98 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.32002550 |
99 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.31239789 |
100 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.31199457 |
101 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.31013534 |
102 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.30929955 |
103 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.30625852 |
104 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.30243625 |
105 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.29939610 |
106 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.29764186 |
107 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.28931982 |
108 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.28615452 |
109 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.27192384 |
110 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.27186914 |
111 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.26332036 |
112 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.26278046 |
113 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.24759889 |
114 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.22325716 |
115 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.22136664 |
116 | Adherens junction_Homo sapiens_hsa04520 | 0.18552942 |
117 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.17774726 |
118 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.17149829 |
119 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.17033601 |
120 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.16905364 |
121 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.16648698 |
122 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.16502643 |
123 | Insulin resistance_Homo sapiens_hsa04931 | 0.15255098 |
124 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.14069553 |
125 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.09841366 |
126 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.09713021 |