C1QL1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1locomotory exploration behavior (GO:0035641)6.18169526
2neuron cell-cell adhesion (GO:0007158)6.12336087
3regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.93220291
4regulation of respiratory gaseous exchange by neurological system process (GO:0002087)5.18964722
5axon ensheathment in central nervous system (GO:0032291)4.98688146
6central nervous system myelination (GO:0022010)4.98688146
7regulation of inhibitory postsynaptic membrane potential (GO:0060080)4.86152261
8postsynaptic membrane organization (GO:0001941)4.85734092
9positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.83717607
10oligodendrocyte differentiation (GO:0048709)4.78995014
11cell migration in hindbrain (GO:0021535)4.78162345
12protein localization to synapse (GO:0035418)4.77635556
13regulation of glutamate receptor signaling pathway (GO:1900449)4.76328827
14nephron tubule formation (GO:0072079)4.72098394
15photoreceptor cell differentiation (GO:0046530)4.68449773
16eye photoreceptor cell differentiation (GO:0001754)4.68449773
17vocalization behavior (GO:0071625)4.66515884
18enteric nervous system development (GO:0048484)4.61890891
19positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.60463114
20neuron projection regeneration (GO:0031102)4.39115356
21regulation of short-term neuronal synaptic plasticity (GO:0048172)4.35213876
22positive regulation of osteoblast proliferation (GO:0033690)4.31256402
23layer formation in cerebral cortex (GO:0021819)4.27832776
24exploration behavior (GO:0035640)4.25258369
25synaptic vesicle maturation (GO:0016188)4.19647267
26astrocyte development (GO:0014002)4.19067074
27dendritic spine morphogenesis (GO:0060997)4.12452219
28regulation of respiratory system process (GO:0044065)4.10190236
29response to dietary excess (GO:0002021)4.01555972
30response to pheromone (GO:0019236)4.00489880
31positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.99970394
32regulation of respiratory gaseous exchange (GO:0043576)3.94984888
33presynaptic membrane assembly (GO:0097105)3.87356835
34positive regulation of synapse assembly (GO:0051965)3.82281474
35neurotransmitter-gated ion channel clustering (GO:0072578)3.78312863
36glial cell differentiation (GO:0010001)3.74358431
37startle response (GO:0001964)3.68845699
38chondroitin sulfate catabolic process (GO:0030207)3.64658304
39response to auditory stimulus (GO:0010996)3.54099807
40presynaptic membrane organization (GO:0097090)3.53024874
41innervation (GO:0060384)3.51135588
42potassium ion import (GO:0010107)3.46297918
43ionotropic glutamate receptor signaling pathway (GO:0035235)3.45375150
44negative regulation of microtubule polymerization (GO:0031115)3.43101180
45chondroitin sulfate biosynthetic process (GO:0030206)3.42476910
46synaptic vesicle docking involved in exocytosis (GO:0016081)3.42080057
47positive regulation of synaptic transmission, GABAergic (GO:0032230)3.40957368
48negative regulation of myoblast differentiation (GO:0045662)3.38394859
49cell communication by electrical coupling (GO:0010644)3.38250996
50adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)3.38168998
51sodium ion export (GO:0071436)3.38086870
52membrane hyperpolarization (GO:0060081)3.37420455
53positive regulation of gliogenesis (GO:0014015)3.36879448
54auditory behavior (GO:0031223)3.35391841
55regulation of synaptic vesicle exocytosis (GO:2000300)3.34940309
56neuron recognition (GO:0008038)3.32493300
57regulation of synapse structural plasticity (GO:0051823)3.30030566
58negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.27440693
59negative regulation of catenin import into nucleus (GO:0035414)3.26898398
60neurotransmitter secretion (GO:0007269)3.26042932
61neuromuscular process controlling balance (GO:0050885)3.25387412
62cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.21996681
63regulation of neurotransmitter uptake (GO:0051580)3.21474982
64righting reflex (GO:0060013)3.21297903
65glutamate secretion (GO:0014047)3.20878038
66positive regulation of oligodendrocyte differentiation (GO:0048714)3.19307701
67neuronal ion channel clustering (GO:0045161)3.18728932
68dendrite morphogenesis (GO:0048813)3.18642967
69prepulse inhibition (GO:0060134)3.17393329
70endocardial cushion morphogenesis (GO:0003203)3.17387390
71synaptic vesicle exocytosis (GO:0016079)3.15997206
72axonal fasciculation (GO:0007413)3.15050527
73axon regeneration (GO:0031103)3.13280797
74membrane assembly (GO:0071709)3.13029357
75synaptic transmission, glutamatergic (GO:0035249)3.10877510
76post-embryonic morphogenesis (GO:0009886)3.09448537
77positive regulation of neurological system process (GO:0031646)3.09025195
78regulation of rhodopsin mediated signaling pathway (GO:0022400)3.06500482
79cell differentiation in hindbrain (GO:0021533)3.05244713
80gonadal mesoderm development (GO:0007506)3.04245846
81positive regulation of membrane potential (GO:0045838)3.03191543
82positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.02213242
83long-term synaptic potentiation (GO:0060291)3.01688121
84peptidyl-arginine omega-N-methylation (GO:0035247)3.01644913
85rhodopsin mediated signaling pathway (GO:0016056)3.01557501
86peptidyl-arginine N-methylation (GO:0035246)3.01275287
87peptidyl-arginine methylation (GO:0018216)3.01275287
88negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.99230318
89positive regulation of inositol phosphate biosynthetic process (GO:0060732)2.99003771
90regulation of neuronal synaptic plasticity (GO:0048168)2.98764158
91retinal rod cell development (GO:0046548)2.98755390
92negative regulation of sodium ion transport (GO:0010766)2.98195821
93regulation of NFAT protein import into nucleus (GO:0051532)2.96413848
94long-term memory (GO:0007616)2.96317919
95positive regulation of branching involved in ureteric bud morphogenesis (GO:0090190)2.95655951
96dermatan sulfate metabolic process (GO:0030205)2.92413415
97peptidyl-tyrosine autophosphorylation (GO:0038083)2.92016810
98cerebellum development (GO:0021549)2.90364541
99heart valve formation (GO:0003188)2.89971440
100regulation of synaptic vesicle transport (GO:1902803)2.89041001
101cellular potassium ion homeostasis (GO:0030007)2.88463547
102dermatan sulfate biosynthetic process (GO:0030208)2.85615713
103amino acid import (GO:0043090)2.84688632
104positive regulation of synapse maturation (GO:0090129)2.84549543
105Sertoli cell development (GO:0060009)2.83795924
106regulation of transmission of nerve impulse (GO:0051969)2.82353569
107cerebellar granule cell differentiation (GO:0021707)2.81586408
108axon development (GO:0061564)2.80249776
109regulation of beta-amyloid formation (GO:1902003)2.78784879
110regulation of postsynaptic membrane potential (GO:0060078)2.78710847
111spinal cord development (GO:0021510)2.77923881
112positive regulation of dendritic spine morphogenesis (GO:0061003)2.77425975
113developmental induction (GO:0031128)2.77295966
114regulation of long-term neuronal synaptic plasticity (GO:0048169)2.76047737
115neuromuscular process (GO:0050905)2.75075290
116regulation of clathrin-mediated endocytosis (GO:2000369)2.74958578
117neurotransmitter transport (GO:0006836)2.74953814
118histone arginine methylation (GO:0034969)2.74501322
119regulation of excitatory postsynaptic membrane potential (GO:0060079)2.74269948
120cerebellar Purkinje cell differentiation (GO:0021702)2.74200053
121dopamine receptor signaling pathway (GO:0007212)2.73512146
122positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.73242884
123positive regulation of mesonephros development (GO:0061213)2.72690534
124myelination (GO:0042552)2.72097109
125cGMP-mediated signaling (GO:0019934)2.71592563
126establishment of mitochondrion localization (GO:0051654)2.70572249
127L-amino acid import (GO:0043092)2.70394515
128synapse organization (GO:0050808)2.70345085
129neuronal action potential propagation (GO:0019227)2.70334153
130regulation of synapse assembly (GO:0051963)2.70189380
131glial cell proliferation (GO:0014009)2.70045535
132potassium ion homeostasis (GO:0055075)2.69707570
133adenosine receptor signaling pathway (GO:0001973)2.69528487
134positive regulation of dendritic spine development (GO:0060999)2.69276041
135cellular response to prostaglandin stimulus (GO:0071379)2.69249460
136astrocyte differentiation (GO:0048708)2.69005234
137regulation of synaptic transmission, glutamatergic (GO:0051966)2.68309354
138cerebellar Purkinje cell layer development (GO:0021680)2.68211354
139ensheathment of neurons (GO:0007272)2.67989738
140axon ensheathment (GO:0008366)2.67989738
141regulation of extracellular matrix disassembly (GO:0010715)2.66151010
142cell-cell junction maintenance (GO:0045217)2.65835015
143mesenchyme morphogenesis (GO:0072132)2.65661874
144thalamus development (GO:0021794)2.62748325
145cell-cell signaling involved in cell fate commitment (GO:0045168)2.62447131
146mechanosensory behavior (GO:0007638)2.61292506
147negative regulation of neurotransmitter secretion (GO:0046929)2.60449126
148chondroitin sulfate metabolic process (GO:0030204)2.58603532
149regulation of inclusion body assembly (GO:0090083)2.58371347
150myelin maintenance (GO:0043217)2.57603092
151neurotransmitter catabolic process (GO:0042135)2.55965635
152protein retention in ER lumen (GO:0006621)2.54022203
153myelination in peripheral nervous system (GO:0022011)2.53720420

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.67054958
2* JARID2_20064375_ChIP-Seq_MESCs_Mouse3.10805247
3NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.91937227
4* EZH2_27304074_Chip-Seq_ESCs_Mouse2.89741798
5TRIM28_21343339_ChIP-Seq_HEK293_Human2.88953864
6* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.85956371
7* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.85956371
8THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.79068387
9CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.77846793
10* SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.72809972
11EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.72162144
12* SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.69190153
13* JARID2_20075857_ChIP-Seq_MESCs_Mouse2.67880233
14ERG_21242973_ChIP-ChIP_JURKAT_Human2.57989120
15* RNF2_27304074_Chip-Seq_ESCs_Mouse2.46536868
16* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.44098085
17SUZ12_27294783_Chip-Seq_ESCs_Mouse2.39521761
18EED_16625203_ChIP-ChIP_MESCs_Mouse2.38680854
19REST_21632747_ChIP-Seq_MESCs_Mouse2.37744272
20* EZH2_27294783_Chip-Seq_ESCs_Mouse2.32568756
21ZFP281_18757296_ChIP-ChIP_E14_Mouse2.31486565
22AR_21572438_ChIP-Seq_LNCaP_Human2.30049348
23* SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.27511799
24MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.22033343
25* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.21085399
26* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.19988975
27* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.17916316
28TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.13891870
29ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.08474425
30RARB_27405468_Chip-Seq_BRAIN_Mouse2.08106070
31REST_18959480_ChIP-ChIP_MESCs_Mouse2.05848379
32ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.05166670
33GBX2_23144817_ChIP-Seq_PC3_Human2.00347462
34STAT6_21828071_ChIP-Seq_BEAS2B_Human1.98589976
35* RING1B_27294783_Chip-Seq_NPCs_Mouse1.91798423
36PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.90921198
37* RING1B_27294783_Chip-Seq_ESCs_Mouse1.85245547
38KDM2B_26808549_Chip-Seq_K562_Human1.83374165
39ZFP281_27345836_Chip-Seq_ESCs_Mouse1.73884227
40* CBX2_27304074_Chip-Seq_ESCs_Mouse1.73106669
41IKZF1_21737484_ChIP-ChIP_HCT116_Human1.71640318
42RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.68939203
43SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.65187292
44TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.65143050
45DROSHA_22980978_ChIP-Seq_HELA_Human1.61583751
46RARG_19884340_ChIP-ChIP_MEFs_Mouse1.55112111
47CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.48226440
48SRY_22984422_ChIP-ChIP_TESTIS_Rat1.46409086
49EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.46347629
50OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.45264309
51WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.45051692
52RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.39933109
53GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.39402291
54SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.38998136
55ZNF274_21170338_ChIP-Seq_K562_Hela1.35218862
56* TP53_20018659_ChIP-ChIP_R1E_Mouse1.35097560
57TET1_21451524_ChIP-Seq_MESCs_Mouse1.34383635
58DNAJC2_21179169_ChIP-ChIP_NT2_Human1.31138116
59* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.30867142
60SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.29486198
61DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.29337443
62SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.27441924
63MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.24808544
64ESR2_21235772_ChIP-Seq_MCF-7_Human1.24626244
65* KDM2B_26808549_Chip-Seq_JURKAT_Human1.23427740
66* SMC4_20622854_ChIP-Seq_HELA_Human1.22562087
67TP63_17297297_ChIP-ChIP_HaCaT_Human1.22289537
68CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.22223903
69RNF2_27304074_Chip-Seq_NSC_Mouse1.22031953
70CTBP2_25329375_ChIP-Seq_LNCAP_Human1.18996785
71KDM2B_26808549_Chip-Seq_SUP-B15_Human1.16307768
72RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.15475254
73CLOCK_20551151_ChIP-Seq_293T_Human1.14297520
74RACK7_27058665_Chip-Seq_MCF-7_Human1.13987819
75POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.12561320
76ESR1_15608294_ChIP-ChIP_MCF-7_Human1.10353247
77TP53_23651856_ChIP-Seq_MEFs_Mouse1.08815239
78SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.08798138
79CTCF_27219007_Chip-Seq_Bcells_Human1.08767547
80GATA1_26923725_Chip-Seq_HPCs_Mouse1.07759503
81ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.07498977
82KDM2B_26808549_Chip-Seq_DND41_Human1.05729393
83AR_19668381_ChIP-Seq_PC3_Human1.05482973
84P68_20966046_ChIP-Seq_HELA_Human1.05323720
85P300_27058665_Chip-Seq_ZR-75-30cells_Human1.05147593
86SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.04600268
87SA1_27219007_Chip-Seq_ERYTHROID_Human1.03489224
88KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.03252782
89* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.02633153
90LXR_22292898_ChIP-Seq_THP-1_Human1.02513271
91POU5F1_16153702_ChIP-ChIP_HESCs_Human1.02493128
92CTBP1_25329375_ChIP-Seq_LNCAP_Human0.99094664
93ELK3_25401928_ChIP-Seq_HUVEC_Human0.99083294
94ZNF263_19887448_ChIP-Seq_K562_Human0.98990858
95NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.98932553
96POU5F1_16518401_ChIP-PET_MESCs_Mouse0.98644287
97PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.98105343
98TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.97854055
99PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.96377285
100SMC1_22415368_ChIP-Seq_MEFs_Mouse0.96268960
101PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.95061280
102YAP1_20516196_ChIP-Seq_MESCs_Mouse0.94838962
103CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94241503
104NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.94170624
105CREB1_26743006_Chip-Seq_LNCaP_Human0.94092732
106RUNX1_26923725_Chip-Seq_HPCs_Mouse0.93953670
107NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.92894453
108* SOX3_22085726_ChIP-Seq_NPCs_Mouse0.92311351
109TET1_21490601_ChIP-Seq_MESCs_Mouse0.91782556
110* CTCF_27219007_Chip-Seq_ERYTHROID_Human0.90992203
111SMAD3_21741376_ChIP-Seq_ESCs_Human0.90503474
112RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.89374120
113KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.89235192
114RBPJ_22232070_ChIP-Seq_NCS_Mouse0.89100680
115CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.88685906
116TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.87623320
117NR3C1_23031785_ChIP-Seq_PC12_Mouse0.87256876
118* CTCF_18555785_ChIP-Seq_MESCs_Mouse0.86526389
119POU3F1_26484290_ChIP-Seq_ESCss_Mouse0.86464522
120SOX2_16153702_ChIP-ChIP_HESCs_Human0.86228231
121* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.85869184
122NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.85546027
123SOX2_21211035_ChIP-Seq_LN229_Gbm0.85165058
124POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.83622392
125CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.81925150
126* BMI1_23680149_ChIP-Seq_NPCS_Mouse0.79619359
127ISL1_27105846_Chip-Seq_CPCs_Mouse0.79595479
128P53_22127205_ChIP-Seq_FIBROBLAST_Human0.78234171
129POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.77614255
130TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.77614255
131TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.76654112
132PRDM14_21183938_ChIP-Seq_MESCs_Mouse0.76352357
133MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.75835592

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity3.89787813
2MP0003880_abnormal_central_pattern3.75124133
3MP0005423_abnormal_somatic_nervous3.74549704
4MP0003011_delayed_dark_adaptation3.30054226
5MP0002638_abnormal_pupillary_reflex2.96431015
6MP0003635_abnormal_synaptic_transmissio2.79638160
7MP0005551_abnormal_eye_electrophysiolog2.67698101
8MP0002653_abnormal_ependyma_morphology2.62465442
9MP0004858_abnormal_nervous_system2.38034149
10MP0002877_abnormal_melanocyte_morpholog2.32267926
11MP0006072_abnormal_retinal_apoptosis2.31553502
12MP0004885_abnormal_endolymph2.29813424
13MP0004270_analgesia2.26912619
14MP0000778_abnormal_nervous_system2.24771801
15MP0002063_abnormal_learning/memory/cond2.22685651
16MP0001486_abnormal_startle_reflex2.19406927
17MP0005253_abnormal_eye_physiology2.14704569
18MP0000920_abnormal_myelination2.11596236
19MP0003123_paternal_imprinting2.09061527
20MP0002064_seizures2.07499575
21MP0009379_abnormal_foot_pigmentation2.05203301
22MP0003136_yellow_coat_color2.03581973
23MP0001188_hyperpigmentation1.98769607
24MP0009780_abnormal_chondrocyte_physiolo1.96984521
25MP0003122_maternal_imprinting1.92321122
26MP0009745_abnormal_behavioral_response1.91627328
27MP0001968_abnormal_touch/_nociception1.88992554
28MP0009046_muscle_twitch1.79932525
29MP0003941_abnormal_skin_development1.78917718
30MP0002572_abnormal_emotion/affect_behav1.78701265
31MP0003787_abnormal_imprinting1.73576062
32MP0005645_abnormal_hypothalamus_physiol1.72753506
33MP0002184_abnormal_innervation1.71254730
34MP0002272_abnormal_nervous_system1.68873914
35MP0000955_abnormal_spinal_cord1.67190545
36MP0002882_abnormal_neuron_morphology1.64770398
37MP0002249_abnormal_larynx_morphology1.64419390
38MP0002734_abnormal_mechanical_nocicepti1.62705160
39MP0002909_abnormal_adrenal_gland1.58721733
40MP0002067_abnormal_sensory_capabilities1.58632298
41MP0003705_abnormal_hypodermis_morpholog1.57815342
42MP0002735_abnormal_chemical_nociception1.48051953
43MP0002557_abnormal_social/conspecific_i1.47575143
44MP0004811_abnormal_neuron_physiology1.47382434
45MP0002152_abnormal_brain_morphology1.45568742
46MP0000462_abnormal_digestive_system1.45459060
47MP0002822_catalepsy1.43894156
48MP0002733_abnormal_thermal_nociception1.42159789
49MP0000579_abnormal_nail_morphology1.39245666
50MP0001984_abnormal_olfaction1.38799513
51MP0004742_abnormal_vestibular_system1.37958580
52MP0003861_abnormal_nervous_system1.37828952
53MP0003183_abnormal_peptide_metabolism1.37074793
54MP0005171_absent_coat_pigmentation1.35926470
55MP0002752_abnormal_somatic_nervous1.34170375
56MP0003633_abnormal_nervous_system1.30264160
57MP0003634_abnormal_glial_cell1.29522210
58MP0000537_abnormal_urethra_morphology1.29286783
59MP0001502_abnormal_circadian_rhythm1.28815737
60MP0003879_abnormal_hair_cell1.28398510
61MP0005391_vision/eye_phenotype1.27875848
62MP0008877_abnormal_DNA_methylation1.27109776
63MP0003329_amyloid_beta_deposits1.25882585
64MP0000762_abnormal_tongue_morphology1.25104864
65MP0000534_abnormal_ureter_morphology1.24565462
66MP0001905_abnormal_dopamine_level1.23715926
67MP0001970_abnormal_pain_threshold1.21730630
68MP0005195_abnormal_posterior_eye1.19900088
69MP0001529_abnormal_vocalization1.19088143
70MP0002736_abnormal_nociception_after1.17973291
71MP0002066_abnormal_motor_capabilities/c1.17637654
72MP0008569_lethality_at_weaning1.17265886
73MP0006276_abnormal_autonomic_nervous1.16995961
74MP0003121_genomic_imprinting1.16421407
75MP0005409_darkened_coat_color1.15785384
76MP0005646_abnormal_pituitary_gland1.14868556
77MP0003172_abnormal_lysosome_physiology1.14634712
78MP0000631_abnormal_neuroendocrine_gland1.14373350
79MP0004142_abnormal_muscle_tone1.14232435
80MP0003631_nervous_system_phenotype1.08884752
81MP0003942_abnormal_urinary_system1.08011468
82MP0002229_neurodegeneration1.07910187
83MP0001440_abnormal_grooming_behavior1.07514828
84MP0005623_abnormal_meninges_morphology1.06544857
85MP0003119_abnormal_digestive_system1.06359380
86MP0010030_abnormal_orbit_morphology1.05575966
87MP0005379_endocrine/exocrine_gland_phen1.05246075
88MP0003890_abnormal_embryonic-extraembry1.05067307
89MP0001299_abnormal_eye_distance/1.05023138
90MP0005394_taste/olfaction_phenotype1.04928443
91MP0005499_abnormal_olfactory_system1.04928443
92MP0009840_abnormal_foam_cell1.04725644
93MP0003385_abnormal_body_wall1.04435398
94MP0002282_abnormal_trachea_morphology0.98057600
95MP0000049_abnormal_middle_ear0.97215728
96MP0000428_abnormal_craniofacial_morphol0.94929453
97MP0002089_abnormal_postnatal_growth/wei0.94236079
98MP0002751_abnormal_autonomic_nervous0.94078815
99MP0000604_amyloidosis0.92789124
100MP0003091_abnormal_cell_migration0.91143107
101MP0003632_abnormal_nervous_system0.90544440
102MP0000733_abnormal_muscle_development0.90416704
103MP0004133_heterotaxia0.89321055
104MP0003690_abnormal_glial_cell0.89077808
105MP0004924_abnormal_behavior0.87354950
106MP0005386_behavior/neurological_phenoty0.87354950
107MP0005670_abnormal_white_adipose0.86992980
108MP0001958_emphysema0.86668050
109MP0003075_altered_response_to0.86517199
110MP0000678_abnormal_parathyroid_gland0.85926572
111MP0002090_abnormal_vision0.85515118
112MP0009250_abnormal_appendicular_skeleto0.83441622
113MP0001501_abnormal_sleep_pattern0.82457351
114MP0004233_abnormal_muscle_weight0.81704554
115MP0005187_abnormal_penis_morphology0.81224933
116MP0003115_abnormal_respiratory_system0.80898981
117MP0001963_abnormal_hearing_physiology0.80832124
118MP0003938_abnormal_ear_development0.80728854
119MP0001943_abnormal_respiration0.80707678
120MP0000026_abnormal_inner_ear0.79972725
121MP0000467_abnormal_esophagus_morphology0.79328934
122MP0003755_abnormal_palate_morphology0.79168733
123MP0000681_abnormal_thyroid_gland0.79123120
124MP0002081_perinatal_lethality0.77257523
125MP0001944_abnormal_pancreas_morphology0.77143441
126MP0008789_abnormal_olfactory_epithelium0.76944497
127MP0002116_abnormal_craniofacial_bone0.76854804
128MP0003283_abnormal_digestive_organ0.75808244
129MP0003137_abnormal_impulse_conducting0.75108290
130MP0006292_abnormal_olfactory_placode0.73576311
131MP0000003_abnormal_adipose_tissue0.72609962
132MP0005167_abnormal_blood-brain_barrier0.72549171
133MP0000747_muscle_weakness0.71436559
134MP0002697_abnormal_eye_size0.71396534
135MP0005257_abnormal_intraocular_pressure0.70694789
136MP0005595_abnormal_vascular_smooth0.68994405
137MP0000639_abnormal_adrenal_gland0.68014715
138MP0005058_abnormal_lysosome_morphology0.66380442

Predicted human phenotypes

RankGene SetZ-score
1Neurofibrillary tangles (HP:0002185)4.82125992
2Congenital stationary night blindness (HP:0007642)4.68828698
3Absent rod-and cone-mediated responses on ERG (HP:0007688)3.73313981
4Cerebral inclusion bodies (HP:0100314)3.69278828
5Pendular nystagmus (HP:0012043)3.67222457
6Myokymia (HP:0002411)3.63058680
7Bony spicule pigmentary retinopathy (HP:0007737)3.59267110
8Abnormal rod and cone electroretinograms (HP:0008323)3.40130528
9Anomalous pulmonary venous return (HP:0010772)3.37767875
10Scotoma (HP:0000575)3.36405805
11Visual hallucinations (HP:0002367)3.35879975
12Truncus arteriosus (HP:0001660)3.33550143
13Congenital malformation of the right heart (HP:0011723)3.28372288
14Double outlet right ventricle (HP:0001719)3.28372288
15Increased circulating renin level (HP:0000848)3.26962019
16Chorioretinal atrophy (HP:0000533)3.14858085
17Central scotoma (HP:0000603)3.14098308
18Turricephaly (HP:0000262)3.02580287
19Macroorchidism (HP:0000053)3.01119352
20Abnormality of the pulmonary veins (HP:0011718)2.97657849
21Abnormality of the 4th metacarpal (HP:0010012)2.93666232
22Hyperparathyroidism (HP:0000843)2.93061038
23Hyperacusis (HP:0010780)2.86896173
24Enlarged penis (HP:0000040)2.86776342
25Megalencephaly (HP:0001355)2.80787396
26Morphological abnormality of the middle ear (HP:0008609)2.78531524
27Abnormality of macular pigmentation (HP:0008002)2.70836245
28Agitation (HP:0000713)2.69228982
29Insomnia (HP:0100785)2.67518083
30Peripheral hypomyelination (HP:0007182)2.64292303
31Obstructive sleep apnea (HP:0002870)2.63366159
32Oligodactyly (hands) (HP:0001180)2.60451900
33Intention tremor (HP:0002080)2.58881888
34Mitral regurgitation (HP:0001653)2.57992833
35Focal motor seizures (HP:0011153)2.54339762
36Shallow orbits (HP:0000586)2.54303158
37Abolished electroretinogram (ERG) (HP:0000550)2.52040171
38Ulnar bowing (HP:0003031)2.50557995
39Focal seizures (HP:0007359)2.49574180
40Supranuclear gaze palsy (HP:0000605)2.49357389
41Abnormality of the lower motor neuron (HP:0002366)2.48973863
42Amblyopia (HP:0000646)2.47691717
43Progressive cerebellar ataxia (HP:0002073)2.44125571
44Ankyloglossia (HP:0010296)2.37140410
45Depression (HP:0000716)2.35650101
46Overriding aorta (HP:0002623)2.35024677
47Action tremor (HP:0002345)2.32824983
48Morphological abnormality of the inner ear (HP:0011390)2.31986535
49Glossoptosis (HP:0000162)2.31889680
50Split foot (HP:0001839)2.30817128
51Renal duplication (HP:0000075)2.30468465
52Hyperthyroidism (HP:0000836)2.29468341
53Synostosis of carpal bones (HP:0005048)2.29000195
54Oligodactyly (HP:0012165)2.24618236
55Hypoglycemic seizures (HP:0002173)2.22512094
56Hypoventilation (HP:0002791)2.22428772
57Decreased central vision (HP:0007663)2.22168057
58Fibular hypoplasia (HP:0003038)2.20871165
59Megalocornea (HP:0000485)2.20175846
60Hypercalcemia (HP:0003072)2.19951503
61Abnormality of the ischium (HP:0003174)2.19836591
62Absent epiphyses (HP:0010577)2.19701686
63Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.19701686
64Menstrual irregularities (HP:0000858)2.18536625
65Elfin facies (HP:0004428)2.18313598
66Type II diabetes mellitus (HP:0005978)2.17324509
67Bowel incontinence (HP:0002607)2.16209061
68Drooling (HP:0002307)2.15933091
69Excessive salivation (HP:0003781)2.15933091
70Urethral obstruction (HP:0000796)2.15420259
71Severe visual impairment (HP:0001141)2.15010495
72Truncal ataxia (HP:0002078)2.11016235
73Neoplasm of the peripheral nervous system (HP:0100007)2.10938763
74Patellar dislocation (HP:0002999)2.10012158
75Broad-based gait (HP:0002136)2.08546660
76Abnormal eating behavior (HP:0100738)2.07741104
77Akinesia (HP:0002304)2.07124458
78Renovascular hypertension (HP:0100817)2.07043000
79Sporadic (HP:0003745)2.05845065
80Abnormality of the diencephalon (HP:0010662)2.04765246
81Dyschromatopsia (HP:0007641)2.04163948
82Bladder diverticulum (HP:0000015)2.03505355
83Ankle clonus (HP:0011448)2.03060284
84Hemiparesis (HP:0001269)2.02257186
85Bowel diverticulosis (HP:0005222)2.01782129
86Pigmentary retinal degeneration (HP:0001146)2.01528407
87Synostosis involving the elbow (HP:0003938)2.00360558
88Humeroradial synostosis (HP:0003041)2.00360558
89Epileptic encephalopathy (HP:0200134)1.99709510
90Posterior subcapsular cataract (HP:0007787)1.99424478
91Polyphagia (HP:0002591)1.98903132
92Aqueductal stenosis (HP:0002410)1.98473759
93Restlessness (HP:0000711)1.97396452
94Hyperventilation (HP:0002883)1.96593523
95Mutism (HP:0002300)1.96063708
96Abnormal large intestine physiology (HP:0012700)1.95477084
97Broad face (HP:0000283)1.95073107
98Venous insufficiency (HP:0005293)1.94779841
99Back pain (HP:0003418)1.93909224
100Abnormality of cochlea (HP:0000375)1.92867408
101Aplasia involving bones of the extremities (HP:0009825)1.92845272
102Aplasia involving bones of the upper limbs (HP:0009823)1.92845272
103Aplasia of the phalanges of the hand (HP:0009802)1.92845272
104Attenuation of retinal blood vessels (HP:0007843)1.92608552
105Poor eye contact (HP:0000817)1.91841810
106Asymmetry of the thorax (HP:0001555)1.90911501
107Sleep apnea (HP:0010535)1.89831869
108Tibial bowing (HP:0002982)1.89249558
109Failure to thrive in infancy (HP:0001531)1.88333322
110Short 4th metacarpal (HP:0010044)1.87382088
111Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.87382088
112Hyperinsulinemic hypoglycemia (HP:0000825)1.86829593
113Limb dystonia (HP:0002451)1.86715978
114Macular degeneration (HP:0000608)1.86280011
115Thickened helices (HP:0000391)1.85924266
116Cerebral hypomyelination (HP:0006808)1.85587513
117Arnold-Chiari malformation (HP:0002308)1.85464989
118Dysdiadochokinesis (HP:0002075)1.83656504
119Hallux valgus (HP:0001822)1.82849258
120Hypercortisolism (HP:0001578)1.81993819
121Unilateral renal agenesis (HP:0000122)1.81763370
122Impaired social interactions (HP:0000735)1.81737999
123Abnormal social behavior (HP:0012433)1.81737999
124Abnormality of binocular vision (HP:0011514)1.81436952
125Diplopia (HP:0000651)1.81436952
126Vertebral clefting (HP:0008428)1.81214740
127Anxiety (HP:0000739)1.81144372
128Abnormality of oral frenula (HP:0000190)1.80825754
129Pointed chin (HP:0000307)1.79637119
130Increased nuchal translucency (HP:0010880)1.79571524
131Exotropia (HP:0000577)1.79100599
132Transposition of the great arteries (HP:0001669)1.79086906
133Abnormal connection of the cardiac segments (HP:0011545)1.79086906
134Abnormal ventriculo-arterial connection (HP:0011563)1.79086906
135Carpal synostosis (HP:0009702)1.78383251
136Short palpebral fissure (HP:0012745)1.76983100
137Absent speech (HP:0001344)1.76149393
138Aplasia/Hypoplasia of the sternum (HP:0006714)1.76124155
139Increased corneal curvature (HP:0100692)1.76113041
140Keratoconus (HP:0000563)1.76113041
141Vitreoretinal degeneration (HP:0000655)1.75442953
142Deviation of the hallux (HP:0010051)1.74799372
143Bell-shaped thorax (HP:0001591)1.74352979
144Venous abnormality (HP:0002624)1.74051410
145Overgrowth (HP:0001548)1.73818565
146Hypoplasia of the iris (HP:0007676)1.72712838
147Hypoplastic ischia (HP:0003175)1.72576849
148Autism (HP:0000717)1.71839942
149Abnormality of the labia minora (HP:0012880)1.70972828
150Adducted thumb (HP:0001181)1.70448899
151Obsessive-compulsive behavior (HP:0000722)1.69638322
152Generalized hypotonia (HP:0001290)1.69222033
153Annular pancreas (HP:0001734)1.69155454
154Septo-optic dysplasia (HP:0100842)1.68598909
155Alacrima (HP:0000522)1.68391330
156Anophthalmia (HP:0000528)1.68070140
157High anterior hairline (HP:0009890)1.67779234
158Mesangial abnormality (HP:0001966)1.67560042
159Mitral stenosis (HP:0001718)1.67255567
160Apathy (HP:0000741)1.66598646
161Missing ribs (HP:0000921)1.66518881
162Abnormality of the aortic arch (HP:0012303)1.66510889
163Cheekbone underdevelopment (HP:0010669)1.66347534
164Hyperextensible skin (HP:0000974)1.65958479
165Genetic anticipation (HP:0003743)1.65809734
166Photophobia (HP:0000613)1.65453937
167Shawl scrotum (HP:0000049)1.64794608
168Precocious puberty (HP:0000826)1.64302919
169Vertebral arch anomaly (HP:0008438)1.64194867
170Flat cornea (HP:0007720)1.61591572
171Choroideremia (HP:0001139)1.59135861

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK34.21980242
2MARK13.55670640
3ICK3.30709466
4CASK3.00235585
5NTRK22.93213062
6PDGFRA2.86508141
7UHMK12.32601417
8PAK62.19242033
9TYRO32.17911691
10PKN12.13584755
11RIPK12.06843249
12MAP3K42.06102647
13PHKG11.93571772
14PHKG21.93571772
15MINK11.91121686
16MAP3K91.90979860
17KSR11.75050965
18CAMK2G1.73682875
19CAMK2B1.64498273
20SMG11.58043595
21NEK61.57782553
22SIK21.57577575
23PNCK1.51451029
24ERBB31.50970511
25PRKD31.48150652
26IRAK21.41645407
27CAMK2D1.38535236
28GRK11.37445701
29TESK11.36647158
30WNK31.34139822
31EPHB21.32769546
32PRPF4B1.32288983
33MAPK131.27451127
34LATS21.26527628
35PTK21.24763189
36TNK21.22560586
37DYRK21.17215739
38CDK51.16495111
39MAP2K71.16351121
40FGFR21.15749594
41DDR21.14573229
42ALK1.14288996
43STK381.13755210
44DYRK1B1.12304586
45CDK181.11899059
46DYRK31.11260975
47CDK151.07355833
48DYRK1A1.06383190
49TAOK11.06175085
50CDK121.05556240
51MARK21.01029733
52CDK11A0.97973387
53LMTK20.97915673
54CSNK1G20.97291358
55CAMK1G0.96987894
56EPHB10.95357552
57CSNK1G30.95320417
58CDK140.94778344
59PDGFRB0.94189919
60MAP2K40.92825672
61TTN0.87488731
62LIMK10.87038033
63PRKCG0.86943045
64MAP2K20.86847912
65PKN20.82498069
66CAMKK10.80773806
67NTRK10.80614650
68EPHA40.80364170
69ARAF0.79838249
70ERBB20.79257262
71DAPK20.77926621
72PLK20.74927984
73PRKCZ0.74618797
74CSNK1A1L0.74533644
75FGFR40.73321062
76SGK30.70896488
77ABL20.70715654
78CDC42BPA0.70539643
79PAK30.70523917
80ILK0.70318840
81SGK2230.69813946
82SGK4940.69813946
83FGR0.69541944
84STK110.67615978
85NEK10.66543975
86PRKCH0.66471687
87GRK50.66430308
88CSNK1G10.66322674
89LRRK20.64837618
90HIPK20.63663900
91DAPK10.63277732
92BRAF0.63115495
93PLK30.62790906
94SIK10.61642129
95SGK20.61593350
96PBK0.60787981
97CAMK40.59940972
98SIK30.59678380
99CSNK1E0.59195767
100TNIK0.59061323
101AKT20.58901134
102MAP3K100.58633203
103EEF2K0.58190601
104ROCK20.57570577
105MAPK90.55888998
106BRSK10.55623295
107SGK10.53791252
108PINK10.52561714
109MAPK100.52505129
110BCR0.52379643
111IRAK30.52170822
112FES0.51826487
113CDC70.51677575
114CAMK1D0.51377374
115ROCK10.50643437
116RET0.50370369
117PAK20.50341003
118ERBB40.50132967
119ADRBK10.49814349
120YES10.49731683
121RPS6KA30.48922612
122MAP3K120.48070152
123KSR20.47838430
124MAPK120.46035956
125CAMK2A0.45636843
126MTOR0.44513231
127MAPKAPK50.44055518
128RPS6KA20.44015659
129MAPK110.43588276
130CSNK1D0.41905225
131TRIB30.40994206
132BMX0.40856567
133PTK60.40198901
134CAMK10.39445983
135CDK10.39165538
136GSK3B0.39036550
137MAP3K20.38694572
138PRKDC0.37361936
139DAPK30.34441815

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047444.86139484
2Synaptic vesicle cycle_Homo sapiens_hsa047212.91180951
3Nicotine addiction_Homo sapiens_hsa050332.75460928
4Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.57621883
5GABAergic synapse_Homo sapiens_hsa047272.37017635
6Glutamatergic synapse_Homo sapiens_hsa047242.21768495
7Nitrogen metabolism_Homo sapiens_hsa009102.06647800
8Dopaminergic synapse_Homo sapiens_hsa047282.03592175
9Circadian entrainment_Homo sapiens_hsa047132.00892482
10Olfactory transduction_Homo sapiens_hsa047402.00461650
11Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.89934046
12Morphine addiction_Homo sapiens_hsa050321.88288164
13Amphetamine addiction_Homo sapiens_hsa050311.88115929
14Cocaine addiction_Homo sapiens_hsa050301.80416171
15Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.79960959
16Gap junction_Homo sapiens_hsa045401.76424565
17Vitamin B6 metabolism_Homo sapiens_hsa007501.72633521
18Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.72263374
19Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.66647525
20Aldosterone synthesis and secretion_Homo sapiens_hsa049251.66605585
21Gastric acid secretion_Homo sapiens_hsa049711.51731873
22Axon guidance_Homo sapiens_hsa043601.51514837
23Insulin secretion_Homo sapiens_hsa049111.48484031
24Cholinergic synapse_Homo sapiens_hsa047251.46710737
25Cardiac muscle contraction_Homo sapiens_hsa042601.46037549
26Chronic myeloid leukemia_Homo sapiens_hsa052201.41201665
27Salivary secretion_Homo sapiens_hsa049701.40841558
28Glioma_Homo sapiens_hsa052141.39248503
29mRNA surveillance pathway_Homo sapiens_hsa030151.35964605
30Long-term potentiation_Homo sapiens_hsa047201.35447402
31GnRH signaling pathway_Homo sapiens_hsa049121.33146650
32Oxytocin signaling pathway_Homo sapiens_hsa049211.32545267
33Oocyte meiosis_Homo sapiens_hsa041141.28940586
34Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.28246429
35Sulfur relay system_Homo sapiens_hsa041221.23633581
36Serotonergic synapse_Homo sapiens_hsa047261.21402569
37Long-term depression_Homo sapiens_hsa047301.21391145
38Renin secretion_Homo sapiens_hsa049241.19454296
39Hedgehog signaling pathway_Homo sapiens_hsa043401.14318545
40Hippo signaling pathway_Homo sapiens_hsa043901.12902604
41Dilated cardiomyopathy_Homo sapiens_hsa054141.10818945
42Phospholipase D signaling pathway_Homo sapiens_hsa040721.10084276
43Bladder cancer_Homo sapiens_hsa052191.09974617
44Pancreatic cancer_Homo sapiens_hsa052121.08837311
45Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.07951166
46Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.06274792
47Melanogenesis_Homo sapiens_hsa049161.06081806
48ErbB signaling pathway_Homo sapiens_hsa040121.02479405
49Estrogen signaling pathway_Homo sapiens_hsa049151.02293725
50Choline metabolism in cancer_Homo sapiens_hsa052311.01871091
51Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.00082635
52Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.98908859
53Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.97167184
54Basal cell carcinoma_Homo sapiens_hsa052170.96539888
55cAMP signaling pathway_Homo sapiens_hsa040240.96125801
56Alcoholism_Homo sapiens_hsa050340.93393575
57Notch signaling pathway_Homo sapiens_hsa043300.92593523
58Wnt signaling pathway_Homo sapiens_hsa043100.92544655
59Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.92414358
60Taste transduction_Homo sapiens_hsa047420.91768012
61Thyroid hormone signaling pathway_Homo sapiens_hsa049190.91253917
62Renal cell carcinoma_Homo sapiens_hsa052110.89320061
63mTOR signaling pathway_Homo sapiens_hsa041500.88235821
64Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.87800608
65Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.87520285
66Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.86960792
67Maturity onset diabetes of the young_Homo sapiens_hsa049500.85838059
68Vibrio cholerae infection_Homo sapiens_hsa051100.84686440
69MAPK signaling pathway_Homo sapiens_hsa040100.83941074
70AMPK signaling pathway_Homo sapiens_hsa041520.82662909
71Calcium signaling pathway_Homo sapiens_hsa040200.79909474
72Central carbon metabolism in cancer_Homo sapiens_hsa052300.77062697
73Focal adhesion_Homo sapiens_hsa045100.75972082
74MicroRNAs in cancer_Homo sapiens_hsa052060.75006669
75Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.74698231
76Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.73118041
77Spliceosome_Homo sapiens_hsa030400.72846854
78Endometrial cancer_Homo sapiens_hsa052130.72621639
79Dorso-ventral axis formation_Homo sapiens_hsa043200.72209339
80Neurotrophin signaling pathway_Homo sapiens_hsa047220.72010339
81Sphingolipid metabolism_Homo sapiens_hsa006000.71669524
82Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.70554300
83Prion diseases_Homo sapiens_hsa050200.69195354
84Tight junction_Homo sapiens_hsa045300.68484908
85Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.67406215
86Colorectal cancer_Homo sapiens_hsa052100.65164627
87cGMP-PKG signaling pathway_Homo sapiens_hsa040220.64791257
88Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.63723562
89Arginine biosynthesis_Homo sapiens_hsa002200.62757432
90ECM-receptor interaction_Homo sapiens_hsa045120.61627460
91Ovarian steroidogenesis_Homo sapiens_hsa049130.61438864
92Thyroid hormone synthesis_Homo sapiens_hsa049180.61401900
93Type II diabetes mellitus_Homo sapiens_hsa049300.61371317
94beta-Alanine metabolism_Homo sapiens_hsa004100.61041902
95Collecting duct acid secretion_Homo sapiens_hsa049660.59880471
96Endocytosis_Homo sapiens_hsa041440.58259229
97Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.56276367
98Adherens junction_Homo sapiens_hsa045200.56007989
99Cyanoamino acid metabolism_Homo sapiens_hsa004600.55832255
100Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.55685369
101AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.55163252
102Ras signaling pathway_Homo sapiens_hsa040140.53892143
103Phosphatidylinositol signaling system_Homo sapiens_hsa040700.53744467
104Rap1 signaling pathway_Homo sapiens_hsa040150.52944252
105Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.52309186
106Lysine degradation_Homo sapiens_hsa003100.51656142
107Other glycan degradation_Homo sapiens_hsa005110.51055364
108Prolactin signaling pathway_Homo sapiens_hsa049170.50872890
109Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.50149882
110TGF-beta signaling pathway_Homo sapiens_hsa043500.50084600
111Inositol phosphate metabolism_Homo sapiens_hsa005620.49633352
112Bile secretion_Homo sapiens_hsa049760.49160891
113Protein digestion and absorption_Homo sapiens_hsa049740.49082289
114Arginine and proline metabolism_Homo sapiens_hsa003300.48338315
115Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.48317830
116Sphingolipid signaling pathway_Homo sapiens_hsa040710.47575019
117Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.45388034
118VEGF signaling pathway_Homo sapiens_hsa043700.43776840
119Non-small cell lung cancer_Homo sapiens_hsa052230.43412235
120Longevity regulating pathway - mammal_Homo sapiens_hsa042110.43059394
121Insulin signaling pathway_Homo sapiens_hsa049100.42327013
122Carbohydrate digestion and absorption_Homo sapiens_hsa049730.42294216
123Fatty acid biosynthesis_Homo sapiens_hsa000610.41904737
124Melanoma_Homo sapiens_hsa052180.41383085
125Vascular smooth muscle contraction_Homo sapiens_hsa042700.40773138

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