C1QTNF1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1glomerulus development (GO:0032835)6.10908813
2vascular endothelial growth factor signaling pathway (GO:0038084)4.96026295
3low-density lipoprotein particle clearance (GO:0034383)4.70476825
4lymphangiogenesis (GO:0001946)4.37223954
5epithelial cell differentiation involved in kidney development (GO:0035850)4.20553385
6lymph vessel development (GO:0001945)4.12699515
7retina vasculature morphogenesis in camera-type eye (GO:0061299)4.12203893
8positive regulation of protein kinase C signaling (GO:0090037)3.93513889
9renal filtration (GO:0097205)3.77551042
10keratan sulfate catabolic process (GO:0042340)3.74883604
11regulation of axon guidance (GO:1902667)3.64122515
12positive regulation of p38MAPK cascade (GO:1900745)3.62748211
13peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)3.60787124
14barbed-end actin filament capping (GO:0051016)3.55851045
15adhesion of symbiont to host (GO:0044406)3.53734459
16negative regulation of axon guidance (GO:1902668)3.49690004
17cellular response to vascular endothelial growth factor stimulus (GO:0035924)3.38800236
18adhesion of symbiont to host cell (GO:0044650)3.36308192
19virion attachment to host cell (GO:0019062)3.36308192
20extracellular fibril organization (GO:0043206)3.34819130
21glomerular filtration (GO:0003094)3.29397415
22regulation of sequestering of triglyceride (GO:0010889)3.26294905
23positive regulation of vascular permeability (GO:0043117)3.25583440
24cellular response to epinephrine stimulus (GO:0071872)3.21629739
25cell adhesion mediated by integrin (GO:0033627)3.20117385
26basement membrane organization (GO:0071711)3.19411078
27surfactant homeostasis (GO:0043129)3.19063177
28regulation of axon extension involved in axon guidance (GO:0048841)3.15721973
29endothelial cell chemotaxis (GO:0035767)3.15539513
30triglyceride catabolic process (GO:0019433)3.12899326
31kidney mesenchyme development (GO:0072074)3.12559728
32regulation of plasminogen activation (GO:0010755)3.10454003
33collagen fibril organization (GO:0030199)3.09279594
34endothelium development (GO:0003158)3.09048983
35axon extension involved in axon guidance (GO:0048846)3.08719969
36neuron projection extension involved in neuron projection guidance (GO:1902284)3.08719969
37extracellular matrix assembly (GO:0085029)3.08331700
38cardiac myofibril assembly (GO:0055003)3.08208969
39cell migration involved in sprouting angiogenesis (GO:0002042)3.05657901
40fibril organization (GO:0097435)3.05177155
41vascular endothelial growth factor receptor signaling pathway (GO:0048010)3.04823160
42negative regulation of complement activation (GO:0045916)3.02747279
43negative regulation of smooth muscle cell migration (GO:0014912)3.00244214
44complement activation, alternative pathway (GO:0006957)2.99871160
45positive regulation of receptor recycling (GO:0001921)2.98721867
46metanephric mesenchyme development (GO:0072075)2.97412035
47positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.92678744
48multicellular organismal macromolecule metabolic process (GO:0044259)2.88713714
49regulation of cholesterol storage (GO:0010885)2.84920889
50acylglycerol catabolic process (GO:0046464)2.84859078
51neutral lipid catabolic process (GO:0046461)2.84859078
52venous blood vessel morphogenesis (GO:0048845)2.82519459
53cAMP biosynthetic process (GO:0006171)2.82420967
54multicellular organismal catabolic process (GO:0044243)2.82148647
55wound healing, spreading of epidermal cells (GO:0035313)2.81673981
56regulation of membrane protein ectodomain proteolysis (GO:0051043)2.81643623
57regulation of p38MAPK cascade (GO:1900744)2.81491193
58collagen catabolic process (GO:0030574)2.79786069
59branching involved in salivary gland morphogenesis (GO:0060445)2.78764443
60negative regulation of protein activation cascade (GO:2000258)2.78609043
61collagen metabolic process (GO:0032963)2.77324217
62multicellular organismal metabolic process (GO:0044236)2.74890392
63fibrinolysis (GO:0042730)2.74497449
64bundle of His cell to Purkinje myocyte communication (GO:0086069)2.72605824
65regulation of cell migration involved in sprouting angiogenesis (GO:0090049)2.71390373
66transcytosis (GO:0045056)2.70702064
67ovulation from ovarian follicle (GO:0001542)2.68970312
68coronary vasculature morphogenesis (GO:0060977)2.68802240
69regulation of endothelial cell chemotaxis (GO:2001026)2.67527986
70tooth mineralization (GO:0034505)2.67089594
71response to epinephrine (GO:0071871)2.67021080
72chemical homeostasis within a tissue (GO:0048875)2.66214490
73negative regulation of axon extension involved in axon guidance (GO:0048843)2.65815211
74myofibril assembly (GO:0030239)2.64288070
75sprouting angiogenesis (GO:0002040)2.63909035
76dermatan sulfate metabolic process (GO:0030205)2.63897978
77positive regulation of cholesterol efflux (GO:0010875)2.59358428
78lung vasculature development (GO:0060426)2.56650876
79positive regulation of lipid storage (GO:0010884)2.55375197
80negative regulation of protein autophosphorylation (GO:0031953)2.54927622
81* protein heterotrimerization (GO:0070208)2.53480874
82regulation of extracellular matrix disassembly (GO:0010715)2.53351541
83patterning of blood vessels (GO:0001569)2.52548621
84blood vessel endothelial cell migration (GO:0043534)2.51763356
85regulation of apoptotic cell clearance (GO:2000425)2.50422030
86cardiac muscle hypertrophy (GO:0003300)2.49146214
87dermatan sulfate biosynthetic process (GO:0030208)2.46198117
88cell differentiation involved in kidney development (GO:0061005)2.45691277
89opsonization (GO:0008228)2.44982799
90stress fiber assembly (GO:0043149)2.44816047
91cellular response to cadmium ion (GO:0071276)2.44304352
92sarcomere organization (GO:0045214)2.43105173
93regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.42056549
94glial cell migration (GO:0008347)2.41910560
95striated muscle hypertrophy (GO:0014897)2.39614025
96skin morphogenesis (GO:0043589)2.39344823
97regulation of integrin-mediated signaling pathway (GO:2001044)2.37755433
98regulation of the force of heart contraction (GO:0002026)2.36580062
99dopaminergic neuron differentiation (GO:0071542)2.36400335
100complement activation, classical pathway (GO:0006958)2.35820599
101epithelial cell-cell adhesion (GO:0090136)2.35778254
102positive regulation of endothelial cell apoptotic process (GO:2000353)2.35722363
103chondroitin sulfate catabolic process (GO:0030207)2.35682938
104regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO2.35662095
105muscle hypertrophy (GO:0014896)2.35416911
106regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.34145428
107activation of protein kinase A activity (GO:0034199)2.33615240
108regulation of cardioblast differentiation (GO:0051890)2.33348782
109endocrine hormone secretion (GO:0060986)2.32882673
110cell migration involved in heart development (GO:0060973)2.32446451
111complement activation (GO:0006956)2.32194622
112extracellular matrix disassembly (GO:0022617)2.32005461
113negative regulation of fatty acid transport (GO:2000192)2.31672123
114cell-substrate junction assembly (GO:0007044)2.31021017
115chondroitin sulfate biosynthetic process (GO:0030206)2.30774227
116regulation of glomerular filtration (GO:0003093)2.30372142
117cardiac muscle cell proliferation (GO:0060038)2.28394388
118ganglion development (GO:0061548)2.27758545
119positive regulation of fat cell differentiation (GO:0045600)2.27650471
120positive regulation of cell adhesion mediated by integrin (GO:0033630)2.26570187
121positive regulation of cholesterol transport (GO:0032376)2.26501385
122positive regulation of sterol transport (GO:0032373)2.26501385
123peptidyl-glutamic acid carboxylation (GO:0017187)2.26495412
124protein carboxylation (GO:0018214)2.26495412
125phagocytosis, recognition (GO:0006910)2.25588927
126smooth muscle tissue development (GO:0048745)2.25587599
127cardiac muscle adaptation (GO:0014887)2.25535391
128cardiac muscle hypertrophy in response to stress (GO:0014898)2.25535391
129muscle hypertrophy in response to stress (GO:0003299)2.25535391
130regulation of complement activation (GO:0030449)2.25409673
131mesodermal cell differentiation (GO:0048333)2.25307303
132positive regulation of transforming growth factor beta receptor signaling pathway (GO:0030511)2.25087817
133induction of positive chemotaxis (GO:0050930)2.24692589
134myoblast fusion (GO:0007520)2.24676943
135plasma lipoprotein particle clearance (GO:0034381)2.24302978
136regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)2.23547908
137positive regulation of blood vessel endothelial cell migration (GO:0043536)2.22951176
138chondrocyte proliferation (GO:0035988)2.22282187
139regulation of protein activation cascade (GO:2000257)2.22267668
140cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.21382335
141negative regulation of smooth muscle cell proliferation (GO:0048662)2.21172901
142negative regulation of nitric oxide biosynthetic process (GO:0045019)2.20954188
143NADH metabolic process (GO:0006734)2.20757122
144regulation of gonadotropin secretion (GO:0032276)2.20688473
145glycosaminoglycan catabolic process (GO:0006027)2.20315618
146mesonephros development (GO:0001823)2.19898517
147import into cell (GO:0098657)2.19885458
148regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.19650138
149endothelial cell morphogenesis (GO:0001886)2.18984345
150regulation of glucose import in response to insulin stimulus (GO:2001273)2.18671616
151negative regulation of cartilage development (GO:0061037)2.18285973
152diaphragm development (GO:0060539)2.17690422
153ethanol oxidation (GO:0006069)2.16964938
154metanephric epithelium development (GO:0072207)2.16959877
155hyaluronan catabolic process (GO:0030214)2.16807224
156angiogenesis involved in wound healing (GO:0060055)2.16506558
157type B pancreatic cell proliferation (GO:0044342)2.16407461
158platelet-derived growth factor receptor signaling pathway (GO:0048008)2.16324128
159regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030947)2.14277892
160muscle cell migration (GO:0014812)2.13316752
161positive regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030949)2.13221748
162desmosome organization (GO:0002934)2.12903201
163endodermal cell differentiation (GO:0035987)2.11924826
164negative regulation of vasculature development (GO:1901343)2.11913861
165syncytium formation by plasma membrane fusion (GO:0000768)2.11376077
166* negative regulation of hemostasis (GO:1900047)2.10501572
167* negative regulation of blood coagulation (GO:0030195)2.10501572
168negative regulation of chemotaxis (GO:0050922)2.09729582
169apoptotic cell clearance (GO:0043277)2.09579098
170regulation of alkaline phosphatase activity (GO:0010692)2.09090117
171atrioventricular valve morphogenesis (GO:0003181)2.08927274
172glomerular visceral epithelial cell development (GO:0072015)11.8347859
173glomerular epithelial cell development (GO:0072310)10.5793085
174glomerular basement membrane development (GO:0032836)10.2478247

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRIM28_21343339_ChIP-Seq_HEK293_Human2.96366344
2TP63_17297297_ChIP-ChIP_HaCaT_Human2.77010411
3BP1_19119308_ChIP-ChIP_Hs578T_Human2.72423584
4EED_16625203_ChIP-ChIP_MESCs_Mouse2.46642337
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.28462882
6ESR1_21235772_ChIP-Seq_MCF-7_Human2.23738781
7SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.20453885
8RNF2_18974828_ChIP-Seq_MESCs_Mouse2.19104886
9EZH2_18974828_ChIP-Seq_MESCs_Mouse2.19104886
10SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.15140800
11ESR1_22446102_ChIP-Seq_UTERUS_Mouse2.13631639
12SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.04349485
13SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.03552750
14RUNX2_24764292_ChIP-Seq_MC3T3_Mouse2.01111330
15TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.00046379
16ESR2_21235772_ChIP-Seq_MCF-7_Human1.96063480
17ELK3_25401928_ChIP-Seq_HUVEC_Human1.94668248
18CDX2_19796622_ChIP-Seq_MESCs_Mouse1.92956727
19ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.92835730
20JARID2_20075857_ChIP-Seq_MESCs_Mouse1.90192640
21PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.87824763
22LXR_22292898_ChIP-Seq_THP-1_Human1.87581140
23TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.87459634
24PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.85348064
25WT1_19549856_ChIP-ChIP_CCG9911_Human1.84834543
26JARID2_20064375_ChIP-Seq_MESCs_Mouse1.84709435
27GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.83331874
28EZH2_22144423_ChIP-Seq_EOC_Human1.83247397
29EZH2_27304074_Chip-Seq_ESCs_Mouse1.80883875
30* RARG_19884340_ChIP-ChIP_MEFs_Mouse1.79909645
31EP300_21415370_ChIP-Seq_HL-1_Mouse1.78221448
32GBX2_23144817_ChIP-Seq_PC3_Human1.74543159
33MTF2_20144788_ChIP-Seq_MESCs_Mouse1.74477658
34PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.74232542
35NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.68045129
36TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.67434569
37KDM2B_26808549_Chip-Seq_SUP-B15_Human1.63889228
38NFIB_24661679_ChIP-Seq_LUNG_Mouse1.60297802
39EZH2_27294783_Chip-Seq_ESCs_Mouse1.60028824
40MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.59782623
41RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.59544394
42RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.58514292
43* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.57797215
44* CLOCK_20551151_ChIP-Seq_293T_Human1.57583389
45ZNF217_24962896_ChIP-Seq_MCF-7_Human1.55730561
46SMAD_19615063_ChIP-ChIP_OVARY_Human1.52953733
47PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.51885148
48NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.50743225
49RXR_22158963_ChIP-Seq_LIVER_Mouse1.49003390
50SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.48881210
51GATA2_21666600_ChIP-Seq_HMVEC_Human1.45338673
52RNF2_27304074_Chip-Seq_ESCs_Mouse1.45098511
53LXR_22158963_ChIP-Seq_LIVER_Mouse1.41233861
54CJUN_26792858_Chip-Seq_BT549_Human1.40614834
55KDM2B_26808549_Chip-Seq_K562_Human1.38358185
56AHR_22903824_ChIP-Seq_MCF-7_Human1.37343668
57* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.33951706
58ESR1_20079471_ChIP-ChIP_T-47D_Human1.31165405
59TP53_18474530_ChIP-ChIP_U2OS_Human1.30653872
60NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.30028086
61WT1_25993318_ChIP-Seq_PODOCYTE_Human1.29926491
62THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.27000982
63SMC3_22415368_ChIP-Seq_MEFs_Mouse1.26774131
64PIAS1_25552417_ChIP-Seq_VCAP_Human1.25883178
65* RACK7_27058665_Chip-Seq_MCF-7_Human1.25848720
66* BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.25759010
67UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.24663363
68TP53_20018659_ChIP-ChIP_R1E_Mouse1.23875547
69SMC1_22415368_ChIP-Seq_MEFs_Mouse1.22756868
70HIF1A_21447827_ChIP-Seq_MCF-7_Human1.22522853
71CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.21377917
72ARNT_22903824_ChIP-Seq_MCF-7_Human1.21298665
73AR_21572438_ChIP-Seq_LNCaP_Human1.21274175
74DNAJC2_21179169_ChIP-ChIP_NT2_Human1.20645913
75* PPAR_26484153_Chip-Seq_NCI-H1993_Human1.18423701
76STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.17477199
77* BMI1_23680149_ChIP-Seq_NPCS_Mouse1.14818155
78ERG_21242973_ChIP-ChIP_JURKAT_Human1.13433923
79TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.12425696
80SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.11659560
81DROSHA_22980978_ChIP-Seq_HELA_Human1.11158135
82SOX9_24532713_ChIP-Seq_HFSC_Mouse1.11078536
83NRF2_20460467_ChIP-Seq_MEFs_Mouse1.11061872
84NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.11061872
85CDX2_20551321_ChIP-Seq_CACO-2_Human1.09996156
86FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.08432088
87PPARA_22158963_ChIP-Seq_LIVER_Mouse1.07906992
88P63_26484246_Chip-Seq_KERATINOCYTES_Human1.06677500
89TCF4_18268006_ChIP-ChIP_LS174T_Human1.06568642
90ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.05702208
91TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.05373517
92CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.05331822
93EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.04316484
94WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.04289670
95EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.04071283
96SMAD3_21741376_ChIP-Seq_HESCs_Human1.03563061
97RAD21_21589869_ChIP-Seq_MESCs_Mouse1.03329356
98* KDM2B_26808549_Chip-Seq_DND41_Human1.03104359
99CBX2_27304074_Chip-Seq_ESCs_Mouse1.02845965
100JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.02241891
101JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.01513071
102SA1_22415368_ChIP-Seq_MEFs_Mouse1.01462453
103PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.01169543
104SOX2_20726797_ChIP-Seq_SW620_Human0.99424539
105TP53_16413492_ChIP-PET_HCT116_Human0.99165278
106SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.98719402
107* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.98613549
108AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.98610361
109P300_27058665_Chip-Seq_ZR-75-30cells_Human0.98503504
110EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.98344536
111CTCF_27219007_Chip-Seq_Bcells_Human0.97836934
112STAT6_21828071_ChIP-Seq_BEAS2B_Human0.97675684
113Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.96466746
114TP53_23651856_ChIP-Seq_MEFs_Mouse0.94697582
115FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.94526078
116RING1B_27294783_Chip-Seq_ESCs_Mouse0.94268172
117SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.93609211
118TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.93290073
119SMAD3_21741376_ChIP-Seq_EPCs_Human0.92773523
120RING1B_27294783_Chip-Seq_NPCs_Mouse0.91839658
121ZFP281_18757296_ChIP-ChIP_E14_Mouse0.90986692
122SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.90497022
123FOXO3_23340844_ChIP-Seq_DLD1_Human0.89752339
124* KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.88684136
125SMAD4_21741376_ChIP-Seq_HESCs_Human0.88416501
126* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.87798438
127KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.87052290
128TBX20_22080862_ChIP-Seq_HEART_Mouse0.86701063
129TBX20_22328084_ChIP-Seq_HEART_Mouse0.86701063
130RXR_22108803_ChIP-Seq_LS180_Human0.86311768
131SALL4_18804426_ChIP-ChIP_XEN_Mouse0.86086677
132ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.85385888
133IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.85121523
134TET1_21490601_ChIP-Seq_MESCs_Mouse0.84941262
135* SMC4_20622854_ChIP-Seq_HELA_Human0.84938481
136CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.84557091
137* NR3C1_23031785_ChIP-Seq_PC12_Mouse0.84502611
138PCGF2_27294783_Chip-Seq_NPCs_Mouse0.84382017
139ZFP57_27257070_Chip-Seq_ESCs_Mouse0.83607738
140ISL1_27105846_Chip-Seq_CPCs_Mouse0.83367875
141BCAT_22108803_ChIP-Seq_LS180_Human0.83324241
142* UBF1/2_26484160_Chip-Seq_HMECs_Human0.83085250
143GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.81487067
144FOXM1_26456572_ChIP-Seq_MCF-7_Human0.80723178
145TP63_22573176_ChIP-Seq_HFKS_Human0.80676720
146FOXA2_19822575_ChIP-Seq_HepG2_Human0.80433720
147P300_19829295_ChIP-Seq_ESCs_Human0.79362227
148VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.79203667

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen4.67438060
2MP0004272_abnormal_basement_membrane4.58175332
3MP0010368_abnormal_lymphatic_system4.13504340
4MP0001879_abnormal_lymphatic_vessel3.62823064
5MP0005275_abnormal_skin_tensile3.38470805
6MP0005503_abnormal_tendon_morphology3.10216722
7MP0005623_abnormal_meninges_morphology3.00272736
8MP0000013_abnormal_adipose_tissue2.91335825
9MP0001661_extended_life_span2.63986875
10MP0003724_increased_susceptibility_to2.55469765
11MP0005670_abnormal_white_adipose2.44625736
12MP0006054_spinal_hemorrhage2.26839688
13MP0003279_aneurysm2.22902175
14MP0004510_myositis2.21470806
15MP0001958_emphysema1.91552716
16MP0004084_abnormal_cardiac_muscle1.84274783
17MP0009384_cardiac_valve_regurgitation1.80271989
18MP0003705_abnormal_hypodermis_morpholog1.78119218
19MP0009840_abnormal_foam_cell1.74760907
20MP0002295_abnormal_pulmonary_circulatio1.70983130
21MP0003566_abnormal_cell_adhesion1.57338189
22MP0005023_abnormal_wound_healing1.56708318
23MP0005508_abnormal_skeleton_morphology1.52273823
24MP0005257_abnormal_intraocular_pressure1.51573873
25MP0002971_abnormal_brown_adipose1.50317115
26MP0000230_abnormal_systemic_arterial1.48492421
27MP0000767_abnormal_smooth_muscle1.47832760
28MP0000003_abnormal_adipose_tissue1.46955919
29MP0002060_abnormal_skin_morphology1.46320078
30MP0000579_abnormal_nail_morphology1.41394102
31MP0000462_abnormal_digestive_system1.40141353
32MP0008004_abnormal_stomach_pH1.39188031
33MP0003941_abnormal_skin_development1.39082877
34MP0002972_abnormal_cardiac_muscle1.39052565
35MP0003385_abnormal_body_wall1.38002922
36MP0002896_abnormal_bone_mineralization1.37903893
37MP0003011_delayed_dark_adaptation1.37558229
38MP0004185_abnormal_adipocyte_glucose1.36362184
39MP0005330_cardiomyopathy1.35789882
40MP0004858_abnormal_nervous_system1.31841458
41MP0003942_abnormal_urinary_system1.30904175
42MP0004087_abnormal_muscle_fiber1.28229779
43MP0004130_abnormal_muscle_cell1.27616953
44MP0002254_reproductive_system_inflammat1.27109208
45MP0005595_abnormal_vascular_smooth1.26980125
46MP0005375_adipose_tissue_phenotype1.25896947
47MP0003091_abnormal_cell_migration1.25874530
48MP0004036_abnormal_muscle_relaxation1.24912380
49MP0005666_abnormal_adipose_tissue1.21411800
50MP0002249_abnormal_larynx_morphology1.19930259
51MP0008775_abnormal_heart_ventricle1.17294616
52MP0000163_abnormal_cartilage_morphology1.15734801
53MP0002837_dystrophic_cardiac_calcinosis1.15565804
54MP0003283_abnormal_digestive_organ1.15543966
55MP0002998_abnormal_bone_remodeling1.14582769
56MP0000751_myopathy1.14529990
57MP0006138_congestive_heart_failure1.10795442
58MP0002136_abnormal_kidney_physiology1.10789637
59MP0003329_amyloid_beta_deposits1.10262271
60MP0000759_abnormal_skeletal_muscle1.10182423
61MP0005058_abnormal_lysosome_morphology1.09331890
62MP0003252_abnormal_bile_duct1.09237356
63MP0003191_abnormal_cellular_cholesterol1.07257891
64MP0005167_abnormal_blood-brain_barrier1.07184041
65MP0000750_abnormal_muscle_regeneration1.06839935
66MP0005164_abnormal_response_to1.06697415
67MP0000343_altered_response_to1.05706568
68MP0000749_muscle_degeneration1.05390894
69MP0009643_abnormal_urine_homeostasis1.05335817
70MP0002128_abnormal_blood_circulation1.05018970
71MP0000534_abnormal_ureter_morphology1.04437307
72MP0009250_abnormal_appendicular_skeleto1.01943791
73MP0005165_increased_susceptibility_to1.01379846
74MP0005332_abnormal_amino_acid1.01226747
75MP0010030_abnormal_orbit_morphology1.00438913
76MP0009115_abnormal_fat_cell0.99314120
77MP0000383_abnormal_hair_follicle0.99173590
78MP0003950_abnormal_plasma_membrane0.98954269
79MP0002135_abnormal_kidney_morphology0.98841343
80MP0010329_abnormal_lipoprotein_level0.98148729
81MP0002933_joint_inflammation0.98147256
82MP0002108_abnormal_muscle_morphology0.96795845
83MP0010630_abnormal_cardiac_muscle0.96074921
84MP0005360_urolithiasis0.95346699
85MP0005369_muscle_phenotype0.95246430
86MP0003075_altered_response_to0.94528648
87MP0000647_abnormal_sebaceous_gland0.93912062
88MP0005197_abnormal_uvea_morphology0.93716852
89MP0000566_synostosis0.92471248
90MP0003828_pulmonary_edema0.92317143
91MP0002115_abnormal_skeleton_extremities0.91346586
92MP0002282_abnormal_trachea_morphology0.90885262
93MP0001614_abnormal_blood_vessel0.90606549
94MP0005409_darkened_coat_color0.89910194
95MP0000604_amyloidosis0.89784154
96MP0003303_peritoneal_inflammation0.89630022
97MP0002332_abnormal_exercise_endurance0.89354829
98MP0005334_abnormal_fat_pad0.89300131
99MP0002796_impaired_skin_barrier0.88137518
100MP0005390_skeleton_phenotype0.87854204
101MP0003690_abnormal_glial_cell0.86856662
102MP0005385_cardiovascular_system_phenoty0.85800216
103MP0001544_abnormal_cardiovascular_syste0.85800216
104MP0001542_abnormal_bone_strength0.85561582
105MP0000747_muscle_weakness0.84612740
106MP0003300_gastrointestinal_ulcer0.84608057
107MP0005620_abnormal_muscle_contractility0.83866867
108MP0000762_abnormal_tongue_morphology0.82287110
109MP0002106_abnormal_muscle_physiology0.81597325
110MP0002127_abnormal_cardiovascular_syste0.81453023
111MP0005365_abnormal_bile_salt0.79840670
112MP0005187_abnormal_penis_morphology0.79077327
113MP0001849_ear_inflammation0.78634346
114MP0010386_abnormal_urinary_bladder0.78621547
115MP0002877_abnormal_melanocyte_morpholog0.78074262
116MP0004215_abnormal_myocardial_fiber0.77513609
117MP0001756_abnormal_urination0.77144873
118MP0004019_abnormal_vitamin_homeostasis0.76871260
119MP0001881_abnormal_mammary_gland0.76577017
120MP0003646_muscle_fatigue0.76241943
121MP0002098_abnormal_vibrissa_morphology0.76184609
122MP0001851_eye_inflammation0.75602771
123MP0000049_abnormal_middle_ear0.75567685
124MP0000537_abnormal_urethra_morphology0.75545121
125MP0004484_altered_response_of0.74780215
126MP0000249_abnormal_blood_vessel0.74438652
127MP0002113_abnormal_skeleton_development0.73995106
128MP0002970_abnormal_white_adipose0.73650491
129MP0003045_fibrosis0.73176516
130MP0005535_abnormal_body_temperature0.73048958
131MP0004381_abnormal_hair_follicle0.72491392
132MP0003195_calcinosis0.71615071
133MP0004085_abnormal_heartbeat0.71256188
134MP0003137_abnormal_impulse_conducting0.70899926
135MP0010678_abnormal_skin_adnexa0.70581401
136MP0003453_abnormal_keratinocyte_physiol0.70553300
137MP0004883_abnormal_blood_vessel0.69719313
138MP0001533_abnormal_skeleton_physiology0.69475631
139MP0001348_abnormal_lacrimal_gland0.68515789
140MP0009780_abnormal_chondrocyte_physiolo0.68180812
141MP0002168_other_aberrant_phenotype0.68059226
142MP0000733_abnormal_muscle_development0.66425608

Predicted human phenotypes

RankGene SetZ-score
1Mesangial abnormality (HP:0001966)7.27161055
2Focal segmental glomerulosclerosis (HP:0000097)6.23186225
3Nephritis (HP:0000123)4.77343950
4Glomerulosclerosis (HP:0000096)4.71595914
5Complement deficiency (HP:0004431)4.67677537
6Hypoalbuminemia (HP:0003073)4.62690768
7Abnormal albumin level (HP:0012116)4.62690768
8Premature rupture of membranes (HP:0001788)4.55881896
9Broad metatarsal (HP:0001783)4.26460482
10Abnormality of complement system (HP:0005339)4.22997289
11Glomerulonephritis (HP:0000099)3.99814972
12Deep venous thrombosis (HP:0002625)3.93048024
13Stage 5 chronic kidney disease (HP:0003774)3.92546232
14Systemic lupus erythematosus (HP:0002725)3.81574883
15Aortic dissection (HP:0002647)3.55830311
16Protrusio acetabuli (HP:0003179)3.53818925
17Ankle contracture (HP:0006466)3.42159109
18Vertebral compression fractures (HP:0002953)3.38626498
19Right ventricular cardiomyopathy (HP:0011663)3.31374929
20Abnormality of skeletal muscle fiber size (HP:0012084)3.23963572
21Aortic aneurysm (HP:0004942)3.21355332
22Hypoplasia of the iris (HP:0007676)3.12061472
23Neonatal respiratory distress (HP:0002643)3.11865121
24Cervical subluxation (HP:0003308)3.09538502
25Asymmetric septal hypertrophy (HP:0001670)3.08488833
26Venous insufficiency (HP:0005293)3.05015247
27Follicular hyperkeratosis (HP:0007502)2.99268372
28Corneal erosion (HP:0200020)2.93887436
29Wrist flexion contracture (HP:0001239)2.92759566
30Mildly elevated creatine phosphokinase (HP:0008180)2.87876130
31Lymphangioma (HP:0100764)2.86294880
32Atrophic scars (HP:0001075)2.84356547
33Venous abnormality (HP:0002624)2.80729365
34Overgrowth (HP:0001548)2.80589515
35Joint stiffness (HP:0001387)2.79570419
36Pulmonary artery stenosis (HP:0004415)2.76967651
37Nonimmune hydrops fetalis (HP:0001790)2.76517248
38Nephrotic syndrome (HP:0000100)2.72042808
39Cerebral aneurysm (HP:0004944)2.71953007
40Round ear (HP:0100830)2.69783073
41Coronal craniosynostosis (HP:0004440)2.69503064
42Increased connective tissue (HP:0009025)2.66137232
43Type 1 muscle fiber predominance (HP:0003803)2.61140867
44Mitral stenosis (HP:0001718)2.58500913
45Cardiovascular calcification (HP:0011915)2.58359922
46Hypoproteinemia (HP:0003075)2.58225929
47Lipoatrophy (HP:0100578)2.57841979
48Fragile skin (HP:0001030)2.53456973
49Slender build (HP:0001533)2.53265230
50Acanthosis nigricans (HP:0000956)2.52929884
51Bundle branch block (HP:0011710)2.48566578
52Atrial fibrillation (HP:0005110)2.47285675
53Sudden death (HP:0001699)2.46964559
54Hematuria (HP:0000790)2.45746433
55Short hallux (HP:0010109)2.43650157
56Hydroxyprolinuria (HP:0003080)2.37088194
57Abnormality of proline metabolism (HP:0010907)2.37088194
58Shallow orbits (HP:0000586)2.36932684
59Soft skin (HP:0000977)2.36385693
60Turricephaly (HP:0000262)2.35014067
61Spondylolisthesis (HP:0003302)2.31644858
62Vascular calcification (HP:0004934)2.30808319
63Mitral regurgitation (HP:0001653)2.27816451
64Aortic valve stenosis (HP:0001650)2.27712114
65Aortic regurgitation (HP:0001659)2.27481447
66Joint laxity (HP:0001388)2.27003975
67Biconcave vertebral bodies (HP:0004586)2.25430053
68Hypoplastic ischia (HP:0003175)2.25146451
69Vascular tortuosity (HP:0004948)2.24815054
70Abnormal atrioventricular conduction (HP:0005150)2.23369421
71Recurrent corneal erosions (HP:0000495)2.23182818
72Primary atrial arrhythmia (HP:0001692)2.22143930
73Oligomenorrhea (HP:0000876)2.21988436
74Abnormality of the ischium (HP:0003174)2.21566778
75Striae distensae (HP:0001065)2.21478171
76Genu recurvatum (HP:0002816)2.19567901
77Aneurysm (HP:0002617)2.19509175
78Hematochezia (HP:0002573)2.17433495
79Muscle fiber splitting (HP:0003555)2.17231846
80Proteinuria (HP:0000093)2.16630479
81Hyporeflexia of lower limbs (HP:0002600)2.16468192
82Supraventricular arrhythmia (HP:0005115)2.16057886
83Polycythemia (HP:0001901)2.15677461
84Supraventricular tachycardia (HP:0004755)2.14985912
85Skin nodule (HP:0200036)2.14897754
86Arterial tortuosity (HP:0005116)2.13874063
87Tubular atrophy (HP:0000092)2.13820880
88Peritonitis (HP:0002586)2.13801994
89Osteolytic defects of the phalanges of the hand (HP:0009771)2.13486280
90Osteolytic defects of the hand bones (HP:0009699)2.13486280
91Hypertriglyceridemia (HP:0002155)2.11660658
92Thin bony cortex (HP:0002753)2.11268940
93Abnormality of Sharpey fibers (HP:0100685)2.11214193
94Prolonged partial thromboplastin time (HP:0003645)2.10976256
95Aplasia/Hypoplasia of the hallux (HP:0008362)2.10731329
96Metaphyseal dysplasia (HP:0100255)2.09186976
97Obstructive sleep apnea (HP:0002870)2.08497127
98Bladder diverticulum (HP:0000015)2.08034892
99Atrioventricular block (HP:0001678)2.05576738
100Hypophosphatemia (HP:0002148)2.04508409
101Distal lower limb amyotrophy (HP:0008944)2.04347710
102Polar cataract (HP:0010696)2.03624279
103Joint hemorrhage (HP:0005261)2.02794469
104Abnormality of dentin (HP:0010299)2.02003290
105Axonal loss (HP:0003447)2.01675005
106Increased variability in muscle fiber diameter (HP:0003557)2.01080466
107Blue sclerae (HP:0000592)2.00707790
108Emphysema (HP:0002097)1.99974589
109Heart block (HP:0012722)1.98287958
110Spinal rigidity (HP:0003306)1.98176265
111Coxa vara (HP:0002812)1.97531548
112Nuclear cataract (HP:0100018)1.97451474
113Abnormality of the peritoneum (HP:0002585)1.96353095
114Knee flexion contracture (HP:0006380)1.96340037
115Bradycardia (HP:0001662)1.92836282
116Persistence of primary teeth (HP:0006335)1.92395659
117Prominent supraorbital ridges (HP:0000336)1.91917896
118Ventricular tachycardia (HP:0004756)1.91784279
119Chondrocalcinosis (HP:0000934)1.90599882
120Increased corneal curvature (HP:0100692)1.89195586
121Keratoconus (HP:0000563)1.89195586
122Advanced eruption of teeth (HP:0006288)1.89090392
123Amyloidosis (HP:0011034)1.87221757
124Hyperextensible skin (HP:0000974)1.86357515
125Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.85697556
126Pterygium (HP:0001059)1.85690326
127Wormian bones (HP:0002645)1.84777337
128Dysostosis multiplex (HP:0000943)1.84245622
129Aplasia cutis congenita (HP:0001057)1.83820492
130Abnormality of polysaccharide metabolism (HP:0011012)1.82076880
131Abnormality of glycosaminoglycan metabolism (HP:0004371)1.82076880
132Abnormality of mucopolysaccharide metabolism (HP:0011020)1.82076880
133Generalized amyotrophy (HP:0003700)1.81406451
134Ectopia lentis (HP:0001083)1.80841103
135Mucopolysacchariduria (HP:0008155)1.80801428
136Urinary glycosaminoglycan excretion (HP:0003541)1.80801428
137Mitral valve prolapse (HP:0001634)1.80631648
138Hypoventilation (HP:0002791)1.79032886
139Abnormality of the calf musculature (HP:0001430)1.78709387
140Nonprogressive disorder (HP:0003680)1.78680852
141Preaxial foot polydactyly (HP:0001841)1.78333433
142Neonatal short-limb short stature (HP:0008921)1.77385554
143Hip contracture (HP:0003273)1.75741405
144Limited hip movement (HP:0008800)1.75279232
145Alopecia of scalp (HP:0002293)1.75250879
146Craniofacial hyperostosis (HP:0004493)1.75060393
147Femoral bowing (HP:0002980)1.72333235
148Anomalous pulmonary venous return (HP:0010772)1.71906955
149Myocardial infarction (HP:0001658)1.70805286
150Hypoalphalipoproteinemia (HP:0003233)1.70656893
151Xanthomatosis (HP:0000991)1.70527659
152Elbow flexion contracture (HP:0002987)1.70417200
153Concave nail (HP:0001598)1.70388475
154Down-sloping shoulders (HP:0200021)1.70306036
155Dilatation of the ascending aorta (HP:0005111)1.69920003
156Rapidly progressive (HP:0003678)1.68878878
157Synostosis involving the elbow (HP:0003938)1.66411770
158Humeroradial synostosis (HP:0003041)1.66411770
159Distal lower limb muscle weakness (HP:0009053)1.66280772
160Abnormality of the pulmonary veins (HP:0011718)1.65581758

Predicted kinase interactions (KEA)

RankGene SetZ-score
1KDR4.92528571
2TIE14.55141773
3EPHB24.52062691
4TGFBR23.09798717
5SIK12.82409855
6WNK42.69013395
7MYLK2.68489468
8ERN12.09766078
9BLK2.04705498
10FER1.97257412
11EPHB11.93378423
12EPHA31.91513793
13MAP3K61.91490836
14PDGFRA1.81669446
15CAMK1G1.66151515
16TESK11.62005329
17CASK1.57919024
18TTN1.57781136
19LATS11.53668349
20TRIB31.52034787
21DDR21.49044218
22INSRR1.43267887
23CAMK1D1.40637656
24FGFR41.39993636
25GRK11.38739112
26STK391.24455364
27JAK11.20649640
28TBK11.20465541
29PAK21.19571960
30PAK31.13647963
31MAPKAPK31.13311454
32PIK3CA1.12334817
33PAK41.12109214
34MAP2K11.11604921
35MST1R1.10517222
36PRKD21.08475846
37PTK61.07312201
38ROCK11.06168559
39NEK91.03618950
40TAOK21.03499923
41OXSR10.98686068
42TGFBR10.98008564
43MOS0.96693360
44ICK0.94860961
45IRAK10.90945430
46NTRK10.90284475
47EEF2K0.89152054
48MAPK40.87369613
49MAP3K70.87319487
50IRAK30.86917858
51PTK2B0.85699076
52MAPK70.84968817
53ARAF0.84898296
54MET0.84410732
55GSK3A0.83547020
56TRPM70.83247776
57RPS6KA20.82970981
58LATS20.82755869
59WNK10.82568588
60PRKAA20.82269306
61MAPK150.81094574
62PKN20.81084503
63PKN10.80941881
64PRKCE0.80441358
65MTOR0.80362620
66PTK20.79134236
67NTRK30.79007265
68KIT0.78032518
69OBSCN0.75172131
70HIPK20.74095318
71MAP2K30.73743297
72STK380.72407587
73DMPK0.70859399
74PDPK10.69834221
75ZAP700.69002215
76PHKG20.67699222
77PHKG10.67699222
78LIMK10.67300083
79PIK3CG0.67071196
80MAPK120.67025062
81GRK50.66576490
82GRK70.65973151
83PIM20.65707512
84PDGFRB0.63680654
85DAPK30.62744623
86MAP3K140.61314555
87BMX0.60001260
88CAMK2B0.59625240
89PRKG20.59624461
90RPS6KL10.59204570
91RPS6KC10.59204570
92STK38L0.58455597
93DAPK20.57889471
94FGFR20.57665446
95SIK30.57329922
96CSK0.57202735
97MAP2K20.56977317
98PRKD30.55643435
99ROCK20.53623550
100PRKAA10.53421601
101ADRBK10.53243262
102RET0.52931100
103RPS6KA60.52161388
104FRK0.52141122
105RIPK10.51527454
106PRKD10.51417246
107ERBB40.50085637
108SRC0.50010738
109MAP3K110.49818706
110AKT30.49534413
111CAMK40.48043668
112JAK20.47438891
113CAMK2G0.46406444
114CDC42BPA0.45367521
115IGF1R0.45123957
116IRAK20.45093752
117CAMK2D0.43203601
118MAP3K130.42259508
119EPHA20.41632761
120NTRK20.41631453
121PRPF4B0.41010736
122MAP3K10.40459102
123BMPR1B0.39503757
124INSR0.38919640
125MUSK0.38716170
126PRKACG0.38217830
127MARK10.37574193
128LMTK20.37369445
129NLK0.37299413
130SIK20.35151564
131CAMK10.34872350
132FGFR30.33512540
133FGFR10.33469185
134ABL20.33329805
135MAP3K30.32096777
136MARK20.32078482
137ADRBK20.31798523
138TYK20.30934658
139PINK10.29858417
140JAK30.29384740
141PRKCH0.29310557
142PDK20.29196781

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045123.76103216
2Complement and coagulation cascades_Homo sapiens_hsa046102.63021325
3Focal adhesion_Homo sapiens_hsa045102.24117043
4Protein digestion and absorption_Homo sapiens_hsa049742.14568278
5Prion diseases_Homo sapiens_hsa050202.09360016
6Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.92301142
7Axon guidance_Homo sapiens_hsa043601.90090644
8Amoebiasis_Homo sapiens_hsa051461.89440996
9PPAR signaling pathway_Homo sapiens_hsa033201.81443018
10AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.78406843
11Primary bile acid biosynthesis_Homo sapiens_hsa001201.64891557
12Other glycan degradation_Homo sapiens_hsa005111.61946924
13Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.57975699
14Caffeine metabolism_Homo sapiens_hsa002321.57722363
15Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.57179626
16Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.55846024
17Dilated cardiomyopathy_Homo sapiens_hsa054141.54630427
18Pertussis_Homo sapiens_hsa051331.50292896
19Cyanoamino acid metabolism_Homo sapiens_hsa004601.47686233
20Malaria_Homo sapiens_hsa051441.43568787
21Staphylococcus aureus infection_Homo sapiens_hsa051501.40111194
22Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.36805331
23Small cell lung cancer_Homo sapiens_hsa052221.32079593
24Tryptophan metabolism_Homo sapiens_hsa003801.31612517
25Nitrogen metabolism_Homo sapiens_hsa009101.30300997
26Arginine biosynthesis_Homo sapiens_hsa002201.28585368
27PI3K-Akt signaling pathway_Homo sapiens_hsa041511.19411695
28Fatty acid degradation_Homo sapiens_hsa000711.19138907
29Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.14412686
30Steroid hormone biosynthesis_Homo sapiens_hsa001401.13503544
31ABC transporters_Homo sapiens_hsa020101.12856497
32Renin-angiotensin system_Homo sapiens_hsa046141.12722399
33Fatty acid metabolism_Homo sapiens_hsa012121.11987787
34Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.11811855
35Propanoate metabolism_Homo sapiens_hsa006401.11728871
36Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.09367007
37Aldosterone synthesis and secretion_Homo sapiens_hsa049251.08226415
38beta-Alanine metabolism_Homo sapiens_hsa004101.07167751
39Phenylalanine metabolism_Homo sapiens_hsa003601.06563471
40Histidine metabolism_Homo sapiens_hsa003401.02827290
41Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.01667863
42Vascular smooth muscle contraction_Homo sapiens_hsa042700.95478974
43Glycosaminoglycan degradation_Homo sapiens_hsa005310.95207538
44Fatty acid biosynthesis_Homo sapiens_hsa000610.95198629
45Proteoglycans in cancer_Homo sapiens_hsa052050.93853430
46Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.93674994
47Adherens junction_Homo sapiens_hsa045200.93615004
48Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.92581724
492-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.92229616
50Phospholipase D signaling pathway_Homo sapiens_hsa040720.90004750
51AMPK signaling pathway_Homo sapiens_hsa041520.87883873
52Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.87778236
53Melanoma_Homo sapiens_hsa052180.86127100
54Rap1 signaling pathway_Homo sapiens_hsa040150.86047638
55Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.84928672
56Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.84383353
57Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.84338592
58Chemical carcinogenesis_Homo sapiens_hsa052040.83955183
59Fatty acid elongation_Homo sapiens_hsa000620.83335611
60Regulation of actin cytoskeleton_Homo sapiens_hsa048100.83180554
61Lysine degradation_Homo sapiens_hsa003100.82746807
62Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.81051470
63Bile secretion_Homo sapiens_hsa049760.79707911
64Adipocytokine signaling pathway_Homo sapiens_hsa049200.78649559
65Ras signaling pathway_Homo sapiens_hsa040140.78331544
66Vitamin digestion and absorption_Homo sapiens_hsa049770.76314281
67Osteoclast differentiation_Homo sapiens_hsa043800.76184952
68Dorso-ventral axis formation_Homo sapiens_hsa043200.75551858
69Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.74825952
70Tyrosine metabolism_Homo sapiens_hsa003500.74762496
71Ovarian steroidogenesis_Homo sapiens_hsa049130.74692820
72Sulfur metabolism_Homo sapiens_hsa009200.72891193
73Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.72325861
74GnRH signaling pathway_Homo sapiens_hsa049120.71705914
75Longevity regulating pathway - mammal_Homo sapiens_hsa042110.70570814
76Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.70176030
77Basal cell carcinoma_Homo sapiens_hsa052170.69996251
78Retinol metabolism_Homo sapiens_hsa008300.69647713
79Peroxisome_Homo sapiens_hsa041460.68553142
80Insulin signaling pathway_Homo sapiens_hsa049100.66359868
81Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.65852923
82cGMP-PKG signaling pathway_Homo sapiens_hsa040220.64939736
83Pentose and glucuronate interconversions_Homo sapiens_hsa000400.64873428
84Butanoate metabolism_Homo sapiens_hsa006500.63936358
85Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.63446447
86TGF-beta signaling pathway_Homo sapiens_hsa043500.62751004
87Leukocyte transendothelial migration_Homo sapiens_hsa046700.61981475
88Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.61742616
89Pathways in cancer_Homo sapiens_hsa052000.61374987
90African trypanosomiasis_Homo sapiens_hsa051430.59563530
91Insulin resistance_Homo sapiens_hsa049310.59327982
92Sulfur relay system_Homo sapiens_hsa041220.59313925
93Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.58971880
94Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.58600768
95Galactose metabolism_Homo sapiens_hsa000520.57929082
96Renin secretion_Homo sapiens_hsa049240.56854016
97Pyruvate metabolism_Homo sapiens_hsa006200.56073302
98Tight junction_Homo sapiens_hsa045300.55331925
99Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.55216711
100Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.53811067
101Rheumatoid arthritis_Homo sapiens_hsa053230.53642205
102Gap junction_Homo sapiens_hsa045400.52985361
103Phagosome_Homo sapiens_hsa041450.52178115
104Estrogen signaling pathway_Homo sapiens_hsa049150.51857725
105Hippo signaling pathway_Homo sapiens_hsa043900.51845352
106Hedgehog signaling pathway_Homo sapiens_hsa043400.51532005
107Mineral absorption_Homo sapiens_hsa049780.51460907
108Platelet activation_Homo sapiens_hsa046110.51174170
109Arachidonic acid metabolism_Homo sapiens_hsa005900.50394203
110Pancreatic cancer_Homo sapiens_hsa052120.50192919
111Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.48630634
112cAMP signaling pathway_Homo sapiens_hsa040240.48014867
113Glycerolipid metabolism_Homo sapiens_hsa005610.45930814
114Bladder cancer_Homo sapiens_hsa052190.45798692
115Circadian rhythm_Homo sapiens_hsa047100.45453445
116Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.45420430
117VEGF signaling pathway_Homo sapiens_hsa043700.44913773
118Starch and sucrose metabolism_Homo sapiens_hsa005000.44109723
119Fat digestion and absorption_Homo sapiens_hsa049750.43546530
120Toxoplasmosis_Homo sapiens_hsa051450.42962366
121Renal cell carcinoma_Homo sapiens_hsa052110.42895952
122Cocaine addiction_Homo sapiens_hsa050300.42810015
123Toll-like receptor signaling pathway_Homo sapiens_hsa046200.42697717
124Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.41548246
125Oxytocin signaling pathway_Homo sapiens_hsa049210.41335299
126NF-kappa B signaling pathway_Homo sapiens_hsa040640.41149762
127Jak-STAT signaling pathway_Homo sapiens_hsa046300.40582838
128Salmonella infection_Homo sapiens_hsa051320.40033179
129Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.39957608
130Arginine and proline metabolism_Homo sapiens_hsa003300.39582947
131alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.39546835
132Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.39279083
133Lysosome_Homo sapiens_hsa041420.38914433
134Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.37742617
135TNF signaling pathway_Homo sapiens_hsa046680.37453272
136Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.37252424
137Notch signaling pathway_Homo sapiens_hsa043300.37222957
138Acute myeloid leukemia_Homo sapiens_hsa052210.36755308
139Sphingolipid metabolism_Homo sapiens_hsa006000.36546748

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