C1QTNF3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1keratan sulfate catabolic process (GO:0042340)9.75269146
2cell aggregation (GO:0098743)9.09101631
3cartilage condensation (GO:0001502)9.09101631
4collagen fibril organization (GO:0030199)8.09969041
5notochord development (GO:0030903)7.13372206
6negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948)7.12679055
7peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)7.03546363
8positive regulation of extracellular matrix organization (GO:1903055)6.98438396
9limb bud formation (GO:0060174)6.48299858
10prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:0060526.28046678
11protein retention in ER lumen (GO:0006621)5.65122085
12endothelial cell morphogenesis (GO:0001886)5.58188293
13proteoglycan metabolic process (GO:0006029)5.31861939
14maintenance of protein localization in endoplasmic reticulum (GO:0035437)5.31396970
15embryonic skeletal joint morphogenesis (GO:0060272)5.29677889
16cartilage development (GO:0051216)5.26474893
17regulation of extracellular matrix disassembly (GO:0010715)5.26452974
18skeletal muscle fiber development (GO:0048741)5.17725196
19collagen catabolic process (GO:0030574)5.08403353
20chondroitin sulfate biosynthetic process (GO:0030206)5.00223727
21collagen metabolic process (GO:0032963)4.94403512
22replacement ossification (GO:0036075)4.88706972
23endochondral ossification (GO:0001958)4.88706972
24multicellular organismal catabolic process (GO:0044243)4.65267692
25multicellular organismal macromolecule metabolic process (GO:0044259)4.60858760
26extracellular fibril organization (GO:0043206)4.58996610
27peptidyl-proline hydroxylation (GO:0019511)4.58829655
28regulation of extracellular matrix organization (GO:1903053)4.57332469
29endodermal cell differentiation (GO:0035987)4.54139795
30sphingomyelin metabolic process (GO:0006684)4.53160045
31dermatan sulfate biosynthetic process (GO:0030208)4.42955968
32prostate gland growth (GO:0060736)4.42488077
33negative regulation of heart growth (GO:0061117)4.41492239
34negative regulation of cardiac muscle tissue growth (GO:0055022)4.41492239
35lung lobe morphogenesis (GO:0060463)4.39836562
36nucleotide-sugar biosynthetic process (GO:0009226)4.38939634
37multicellular organismal metabolic process (GO:0044236)4.37048763
38exocrine pancreas development (GO:0031017)4.36213338
39regulation of calcineurin-NFAT signaling cascade (GO:0070884)4.31551720
40positive regulation of chondrocyte differentiation (GO:0032332)4.28427929
41chondrocyte differentiation (GO:0002062)4.25258989
42skeletal system development (GO:0001501)4.24656099
43myotube cell development (GO:0014904)4.24201729
44lipopolysaccharide biosynthetic process (GO:0009103)4.21956300
45cellular glucuronidation (GO:0052695)4.20403623
46positive regulation of cartilage development (GO:0061036)4.18994746
47keratan sulfate biosynthetic process (GO:0018146)4.18071593
48endocardial cushion morphogenesis (GO:0003203)4.14178118
49regulation of plasminogen activation (GO:0010755)4.11773144
50extracellular matrix disassembly (GO:0022617)4.07493414
51chondroitin sulfate catabolic process (GO:0030207)4.01389301
52muscle cell fate commitment (GO:0042693)4.01298598
53short-term memory (GO:0007614)4.01269033
54cellular response to BMP stimulus (GO:0071773)4.01084841
55response to BMP (GO:0071772)4.01084841
56chondrocyte proliferation (GO:0035988)3.99973379
57dermatan sulfate metabolic process (GO:0030205)3.98770901
58skin morphogenesis (GO:0043589)3.90332147
59glucuronate metabolic process (GO:0019585)3.83250164
60uronic acid metabolic process (GO:0006063)3.83250164
61positive regulation of skeletal muscle tissue development (GO:0048643)3.77914582
62presynaptic membrane assembly (GO:0097105)3.74074439
63protein hydroxylation (GO:0018126)3.66806297
64protein heterotrimerization (GO:0070208)3.63879986
65regulation of smooth muscle cell apoptotic process (GO:0034391)3.63378461
66lung vasculature development (GO:0060426)3.62182254
67presynaptic membrane organization (GO:0097090)3.61706131
68embryonic viscerocranium morphogenesis (GO:0048703)3.59314685
69negative regulation of chondrocyte differentiation (GO:0032331)3.58717532
70keratan sulfate metabolic process (GO:0042339)3.58480234
71lipopolysaccharide metabolic process (GO:0008653)3.58463380
72postsynaptic membrane organization (GO:0001941)3.56728272
73response to gravity (GO:0009629)3.55574595
74connective tissue development (GO:0061448)3.55571068
75auditory behavior (GO:0031223)3.54734438
76negative regulation of cartilage development (GO:0061037)3.54635120
77positive regulation of myotube differentiation (GO:0010831)3.52742620
78fibril organization (GO:0097435)3.52260217
79regulation of type B pancreatic cell apoptotic process (GO:2000674)3.51979672
80regulation of chondrocyte differentiation (GO:0032330)3.50689760
81glycosaminoglycan biosynthetic process (GO:0006024)3.50671634
82organ induction (GO:0001759)3.50237091
83regulation of cartilage development (GO:0061035)3.47302558
84ossification (GO:0001503)3.46074352
85branching involved in prostate gland morphogenesis (GO:0060442)3.45780180
86iron ion import (GO:0097286)3.45024403
87aminoglycan biosynthetic process (GO:0006023)3.44753848
88glycoprotein metabolic process (GO:0009100)3.44477609
89lens development in camera-type eye (GO:0002088)3.44299231
90extracellular matrix organization (GO:0030198)3.42677441
91extracellular structure organization (GO:0043062)3.41722921
92negative regulation of smooth muscle cell differentiation (GO:0051151)3.38853662
93glycosaminoglycan catabolic process (GO:0006027)3.37448541
94bone mineralization (GO:0030282)3.33263101
95negative regulation of cardiac muscle tissue development (GO:0055026)3.32781538
96COPII vesicle coating (GO:0048208)3.32348497
97sulfur compound catabolic process (GO:0044273)3.31034683
98hematopoietic stem cell proliferation (GO:0071425)3.29836567
99regulation of integrin-mediated signaling pathway (GO:2001044)3.27856600
100COPI coating of Golgi vesicle (GO:0048205)3.27673468
101Golgi transport vesicle coating (GO:0048200)3.27673468
102chondroitin sulfate metabolic process (GO:0030204)3.27589215
103mesenchyme morphogenesis (GO:0072132)3.27403121
104positive regulation of gastrulation (GO:2000543)3.24636487
105negative regulation of fatty acid transport (GO:2000192)3.24292267
106bone trabecula formation (GO:0060346)3.22012348
107myelin assembly (GO:0032288)3.20501517
108cell migration involved in heart development (GO:0060973)3.19609209
109regulation of odontogenesis (GO:0042481)3.17985022
110aminoglycan catabolic process (GO:0006026)3.15982249
111regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035358)3.15461925
112intraciliary transport (GO:0042073)3.08898071
113lung secretory cell differentiation (GO:0061140)3.07782733
114positive regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001241)3.07079360
115embryonic skeletal system development (GO:0048706)3.06848896
116interkinetic nuclear migration (GO:0022027)3.06815406
117regulation of non-canonical Wnt signaling pathway (GO:2000050)3.05329690
118mechanosensory behavior (GO:0007638)3.05065096
119positive regulation of insulin-like growth factor receptor signaling pathway (GO:0043568)3.04655224
120regulation of organ formation (GO:0003156)3.04463920
121negative regulation of cardiac muscle hypertrophy (GO:0010614)3.04250243
122hypotonic response (GO:0006971)3.03691342
123positive regulation of glycolytic process (GO:0045821)3.03529932
124regulation of cardiac muscle hypertrophy (GO:0010611)2.99518095
125regulation of cardiac muscle cell differentiation (GO:2000725)2.99032049
126tongue development (GO:0043586)2.98710595
127cell proliferation in forebrain (GO:0021846)2.98556603
128dentate gyrus development (GO:0021542)2.96524459
129regulation of response to osmotic stress (GO:0047484)2.95135511
130trivalent inorganic anion homeostasis (GO:0072506)2.94742773
131phosphate ion homeostasis (GO:0055062)2.94742773
132positive regulation of embryonic development (GO:0040019)2.94539818
133regulation of muscle hypertrophy (GO:0014743)2.93579546
134positive regulation of hormone biosynthetic process (GO:0046886)2.92053273
135transmission of nerve impulse (GO:0019226)2.91569335
136metanephric mesenchyme development (GO:0072075)2.90631913
137regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.90510390
138regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.89668527
139regulation of cardiac muscle tissue growth (GO:0055021)2.89420001
140cardiac ventricle formation (GO:0003211)2.87986768
141negative regulation of muscle hypertrophy (GO:0014741)2.87742946
142positive regulation of glycogen biosynthetic process (GO:0045725)2.87147699
143positive regulation of male gonad development (GO:2000020)2.85785000
144middle ear morphogenesis (GO:0042474)2.84984951
145positive regulation of heart growth (GO:0060421)2.84704509
146nephron tubule formation (GO:0072079)2.84480368
147epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.84356535
148heart valve morphogenesis (GO:0003179)2.81752819
149basement membrane organization (GO:0071711)2.79268441
150regulation of establishment or maintenance of cell polarity (GO:0032878)2.78792677
151positive regulation of stem cell differentiation (GO:2000738)2.78491020
152positive regulation of cardiac muscle cell proliferation (GO:0060045)2.77337737
153regulation of secondary heart field cardioblast proliferation (GO:0003266)2.77098598
154regulation of cardioblast proliferation (GO:0003264)2.77098598
155membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.76987988
156regulation of bone mineralization (GO:0030500)2.76230496
157myoblast fusion (GO:0007520)2.76133543
158heart valve formation (GO:0003188)2.75643560
159positive regulation of cardiac muscle tissue growth (GO:0055023)2.75264466
160negative regulation of endothelial cell proliferation (GO:0001937)2.73938221
161regulation of heart growth (GO:0060420)2.73406697
162positive regulation of osteoblast proliferation (GO:0033690)2.72708958
163positive regulation of branching involved in ureteric bud morphogenesis (GO:0090190)2.72173016
164nonmotile primary cilium assembly (GO:0035058)2.71954288
165retinal ganglion cell axon guidance (GO:0031290)2.71909139
166sequestering of extracellular ligand from receptor (GO:0035581)2.64176392
167pericardium development (GO:0060039)2.63633171
168neurotransmitter-gated ion channel clustering (GO:0072578)2.63351449
169negative regulation of biomineral tissue development (GO:0070168)2.62192138
170cardiac chamber formation (GO:0003207)2.59941795
171regulation of muscle adaptation (GO:0043502)2.58223096
172positive regulation of protein import into nucleus, translocation (GO:0033160)2.57374021
173neuron cell-cell adhesion (GO:0007158)2.55868850
174retinal cone cell development (GO:0046549)2.54397369
175axonal fasciculation (GO:0007413)2.53471732
176positive regulation of glycogen metabolic process (GO:0070875)2.52619075
177positive regulation of synapse assembly (GO:0051965)2.52319362
178vocalization behavior (GO:0071625)2.48525550
179negative regulation of neurotransmitter secretion (GO:0046929)2.44183766
180detection of light stimulus involved in sensory perception (GO:0050962)2.42468314
181detection of light stimulus involved in visual perception (GO:0050908)2.42468314
182biomineral tissue development (GO:0031214)2.42370279
183positive regulation of cardiac muscle tissue development (GO:0055025)2.42119408
184positive regulation of muscle hypertrophy (GO:0014742)2.41380993
185positive regulation of cardiac muscle hypertrophy (GO:0010613)2.41380993
186cartilage development involved in endochondral bone morphogenesis (GO:0060351)10.9290583
187chondrocyte development (GO:0002063)10.0008855

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRIM28_21343339_ChIP-Seq_HEK293_Human9.10921064
2TP63_17297297_ChIP-ChIP_HaCaT_Human5.55911565
3AR_21572438_ChIP-Seq_LNCaP_Human3.97697231
4RARG_19884340_ChIP-ChIP_MEFs_Mouse3.84553409
5ESR1_21235772_ChIP-Seq_MCF-7_Human3.29569576
6EZH2_22144423_ChIP-Seq_EOC_Human3.15756836
7TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.09712889
8SMAD_19615063_ChIP-ChIP_OVARY_Human3.09066135
9PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse3.04813153
10GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.03675408
11TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.79443376
12GBX2_23144817_ChIP-Seq_PC3_Human2.76376121
13ZFP57_27257070_Chip-Seq_ESCs_Mouse2.63438198
14GATA1_22025678_ChIP-Seq_K562_Human2.56199948
15CJUN_26792858_Chip-Seq_BT549_Human2.50957040
16RUNX2_24764292_ChIP-Seq_MC3T3_Mouse2.49816081
17TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.46803112
18ESR2_21235772_ChIP-Seq_MCF-7_Human2.40789790
19GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.30653058
20CBX2_27304074_Chip-Seq_ESCs_Mouse2.30047104
21HIF1A_21447827_ChIP-Seq_MCF-7_Human2.29455542
22PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human2.28416679
23WT1_19549856_ChIP-ChIP_CCG9911_Human2.26291507
24POU3F2_20337985_ChIP-ChIP_501MEL_Human2.25922390
25CTBP2_25329375_ChIP-Seq_LNCAP_Human2.09454747
26TAF15_26573619_Chip-Seq_HEK293_Human2.06947665
27CLOCK_20551151_ChIP-Seq_293T_Human2.03703049
28ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.99689629
29VDR_22108803_ChIP-Seq_LS180_Human1.97366294
30RBPJ_22232070_ChIP-Seq_NCS_Mouse1.92462447
31FUS_26573619_Chip-Seq_HEK293_Human1.89216361
32CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.85318946
33* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.83599479
34IGF1R_20145208_ChIP-Seq_DFB_Human1.82464230
35ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.81391258
36* ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.78123785
37* SMAD4_21799915_ChIP-Seq_A2780_Human1.75995093
38TP53_18474530_ChIP-ChIP_U2OS_Human1.75714384
39CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.74059548
40P300_19829295_ChIP-Seq_ESCs_Human1.71996786
41EED_16625203_ChIP-ChIP_MESCs_Mouse1.69969990
42NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.69595499
43NRF2_20460467_ChIP-Seq_MEFs_Mouse1.69595499
44HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.69143006
45BRD4_25478319_ChIP-Seq_HGPS_Human1.63330513
46SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.63175785
47BCAT_22108803_ChIP-Seq_LS180_Human1.61693539
48SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.59330749
49SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.58102766
50DROSHA_22980978_ChIP-Seq_HELA_Human1.56830631
51BMI1_23680149_ChIP-Seq_NPCS_Mouse1.56088028
52CTBP1_25329375_ChIP-Seq_LNCAP_Human1.55177882
53MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.54434571
54JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.53385001
55EZH2_27304074_Chip-Seq_ESCs_Mouse1.53327475
56ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.52982526
57ESR1_20079471_ChIP-ChIP_T-47D_Human1.51733806
58TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.47766370
59EZH2_27294783_Chip-Seq_ESCs_Mouse1.47145001
60JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.46211705
61SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.44895020
62WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.43889581
63TOP2B_26459242_ChIP-Seq_MCF-7_Human1.43056477
64RXR_22108803_ChIP-Seq_LS180_Human1.42895922
65OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.41772976
66ER_23166858_ChIP-Seq_MCF-7_Human1.40391715
67SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.40269256
68SOX2_20726797_ChIP-Seq_SW620_Human1.39690970
69HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.37617723
70NR3C1_21868756_ChIP-Seq_MCF10A_Human1.36424376
71SMC1_22415368_ChIP-Seq_MEFs_Mouse1.36204996
72SUZ12_27294783_Chip-Seq_ESCs_Mouse1.34577901
73EZH2_18974828_ChIP-Seq_MESCs_Mouse1.34173307
74RNF2_18974828_ChIP-Seq_MESCs_Mouse1.34173307
75EWS_26573619_Chip-Seq_HEK293_Human1.34143949
76NANOG_18555785_Chip-Seq_ESCs_Mouse1.33613881
77ZNF217_24962896_ChIP-Seq_MCF-7_Human1.32439705
78RNF2_27304074_Chip-Seq_NSC_Mouse1.31739473
79SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.31447409
80STAT3_23295773_ChIP-Seq_U87_Human1.29863545
81CBP_20019798_ChIP-Seq_JUKART_Human1.29710158
82IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.29710158
83AR_25329375_ChIP-Seq_VCAP_Human1.28410266
84* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.27772353
85SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.27563149
86SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.27563149
87ZNF274_21170338_ChIP-Seq_K562_Hela1.27442191
88SMAD3_21741376_ChIP-Seq_EPCs_Human1.26198684
89TBX20_22328084_ChIP-Seq_HEART_Mouse1.25283013
90TBX20_22080862_ChIP-Seq_HEART_Mouse1.25283013
91TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.25018400
92RING1B_27294783_Chip-Seq_ESCs_Mouse1.24875735
93SALL4_18804426_ChIP-ChIP_XEN_Mouse1.23579771
94EZH2_27294783_Chip-Seq_NPCs_Mouse1.22891887
95FLI1_27457419_Chip-Seq_LIVER_Mouse1.21525623
96KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.20983994
97EP300_21415370_ChIP-Seq_HL-1_Mouse1.20572932
98TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.20305701
99SUZ12_27294783_Chip-Seq_NPCs_Mouse1.19890359
100EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.19372635
101GATA1_26923725_Chip-Seq_HPCs_Mouse1.19370943
102TP53_20018659_ChIP-ChIP_R1E_Mouse1.19220692
103SMC3_22415368_ChIP-Seq_MEFs_Mouse1.18699686
104TAL1_26923725_Chip-Seq_HPCs_Mouse1.17114798
105SA1_22415368_ChIP-Seq_MEFs_Mouse1.16346486
106TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.16281385
107P300_27058665_Chip-Seq_ZR-75-30cells_Human1.15306828
108P53_22387025_ChIP-Seq_ESCs_Mouse1.14310572
109PCGF2_27294783_Chip-Seq_NPCs_Mouse1.13967719
110CDX2_19796622_ChIP-Seq_MESCs_Mouse1.13441711
111TCF4_23295773_ChIP-Seq_U87_Human1.12371386
112NR3C1_23031785_ChIP-Seq_PC12_Mouse1.12230597
113* FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.12011091
114KDM2B_26808549_Chip-Seq_REH_Human1.11844600
115STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.11796210
116* SOX2_21211035_ChIP-Seq_LN229_Gbm1.10948479
117TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.10783805
118REST_21632747_ChIP-Seq_MESCs_Mouse1.10526715
119SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.09253736
120SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.08923348
121PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.07756368
122MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.06846473
123* RUNX2_22187159_ChIP-Seq_PCA_Human1.06492141
124GATA3_24758297_ChIP-Seq_MCF-7_Human1.06384872
125UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.06091110
126VDR_24787735_ChIP-Seq_THP-1_Human1.05783909
127AHR_22903824_ChIP-Seq_MCF-7_Human1.05117360
128TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.04860570
129FLI1_21867929_ChIP-Seq_TH2_Mouse1.04602532
130PPAR_26484153_Chip-Seq_NCI-H1993_Human1.03222634
131UBF1/2_26484160_Chip-Seq_HMECs_Human1.03221877
132SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.01726269
133ELK1_22589737_ChIP-Seq_MCF10A_Human1.01152457
134SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.99723907
135JARID2_20075857_ChIP-Seq_MESCs_Mouse0.99008324
136EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.96745056
137FOXO3_23340844_ChIP-Seq_DLD1_Human0.94848639
138FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.94082530
139* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.93028806
140NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.92339590
141EGR1_19032775_ChIP-ChIP_M12_Human0.91041489
142TP53_22127205_ChIP-Seq_IMR90_Human0.90980748
143PIAS1_25552417_ChIP-Seq_VCAP_Human0.90646075
144ATF3_27146783_Chip-Seq_COLON_Human0.90523456
145MTF2_20144788_ChIP-Seq_MESCs_Mouse0.90444715
146SOX9_24532713_ChIP-Seq_HFSC_Mouse0.90187207
147CTCF_21964334_Chip-Seq_Bcells_Human0.89340793
148NFIB_24661679_ChIP-Seq_LUNG_Mouse0.89238155
149TP53_16413492_ChIP-PET_HCT116_Human0.88262568
150CDX2_20551321_ChIP-Seq_CACO-2_Human0.87962758
151JARID2_20064375_ChIP-Seq_MESCs_Mouse0.86123406
152P63_26484246_Chip-Seq_KERATINOCYTES_Human0.85285664
153ERG_21242973_ChIP-ChIP_JURKAT_Human0.83559243
154TP53_23651856_ChIP-Seq_MEFs_Mouse0.82321022
155FOXM1_26456572_ChIP-Seq_MCF-7_Human0.81862172
156NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.80508422
157TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.80225572
158CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.79212257
159SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.79199404
160* CSB_26484114_Chip-Seq_FIBROBLAST_Human0.78730228
161TP63_23658742_ChIP-Seq_EP156T_Human0.78122653
162KDM2B_26808549_Chip-Seq_K562_Human0.78021531
163MEF2A_21415370_ChIP-Seq_HL-1_Mouse0.77614194
164RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.76003131
165RNF2_27304074_Chip-Seq_ESCs_Mouse0.73526062
166RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.73116667
167SALL1_21062744_ChIP-ChIP_HESCs_Human0.72926456
168PCGF2_27294783_Chip-Seq_ESCs_Mouse0.72847425

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005503_abnormal_tendon_morphology5.76056768
2MP0008438_abnormal_cutaneous_collagen4.86119151
3MP0004134_abnormal_chest_morphology4.51105715
4MP0002933_joint_inflammation4.43745556
5MP0002282_abnormal_trachea_morphology4.37680959
6MP0009250_abnormal_appendicular_skeleto3.55500400
7MP0005275_abnormal_skin_tensile3.42608277
8MP0000163_abnormal_cartilage_morphology3.26030286
9MP0009780_abnormal_chondrocyte_physiolo3.15162216
10MP0002115_abnormal_skeleton_extremities2.75117744
11MP0005508_abnormal_skeleton_morphology2.52222695
12MP0002896_abnormal_bone_mineralization2.51253298
13MP0000751_myopathy2.49653464
14MP0003646_muscle_fatigue2.49365520
15MP0001299_abnormal_eye_distance/2.48209476
16MP0001542_abnormal_bone_strength2.47835192
17MP0002113_abnormal_skeleton_development2.34342245
18MP0002089_abnormal_postnatal_growth/wei2.30255409
19MP0003279_aneurysm2.22311436
20MP0002108_abnormal_muscle_morphology2.19594027
21MP0003705_abnormal_hypodermis_morpholog2.16446955
22MP0005390_skeleton_phenotype2.12862067
23MP0000762_abnormal_tongue_morphology2.05801985
24MP0009384_cardiac_valve_regurgitation2.05023420
25MP0001533_abnormal_skeleton_physiology1.99068892
26MP0001270_distended_abdomen1.97004826
27MP0003123_paternal_imprinting1.95242779
28MP0001958_emphysema1.94601404
29MP0004272_abnormal_basement_membrane1.92696354
30MP0005257_abnormal_intraocular_pressure1.92517648
31MP0000733_abnormal_muscle_development1.89827197
32MP0002109_abnormal_limb_morphology1.77246201
33MP0002249_abnormal_larynx_morphology1.74186078
34MP0000750_abnormal_muscle_regeneration1.68293223
35MP0002163_abnormal_gland_morphology1.65381829
36MP0010030_abnormal_orbit_morphology1.65231396
37MP0003566_abnormal_cell_adhesion1.64381779
38MP0000749_muscle_degeneration1.64093163
39MP0003795_abnormal_bone_structure1.59906352
40MP0002909_abnormal_adrenal_gland1.56083129
41MP0003755_abnormal_palate_morphology1.55484362
42MP0005623_abnormal_meninges_morphology1.45341659
43MP0005171_absent_coat_pigmentation1.43198002
44MP0002938_white_spotting1.39588742
45MP0002116_abnormal_craniofacial_bone1.37426372
46MP0003385_abnormal_body_wall1.32412441
47MP0005023_abnormal_wound_healing1.31695826
48MP0003283_abnormal_digestive_organ1.30345054
49MP0000049_abnormal_middle_ear1.28714973
50MP0003880_abnormal_central_pattern1.28675040
51MP0003938_abnormal_ear_development1.27263979
52MP0006292_abnormal_olfactory_placode1.25941768
53MP0002114_abnormal_axial_skeleton1.22263390
54MP0003091_abnormal_cell_migration1.21525833
55MP0000372_irregular_coat_pigmentation1.21078591
56MP0000778_abnormal_nervous_system1.20944851
57MP0000432_abnormal_head_morphology1.20223545
58MP0006276_abnormal_autonomic_nervous1.20158336
59MP0000566_synostosis1.19939695
60MP0000747_muscle_weakness1.19043650
61MP0002877_abnormal_melanocyte_morpholog1.13483777
62MP0002998_abnormal_bone_remodeling1.11124935
63MP0000759_abnormal_skeletal_muscle1.05836550
64MP0005423_abnormal_somatic_nervous1.05128577
65MP0002233_abnormal_nose_morphology1.04398113
66MP0001188_hyperpigmentation1.03293402
67MP0002932_abnormal_joint_morphology1.02397081
68MP0005253_abnormal_eye_physiology1.01263085
69MP0003935_abnormal_craniofacial_develop1.00728084
70MP0001346_abnormal_lacrimal_gland1.00517947
71MP0003942_abnormal_urinary_system1.00426089
72MP0002111_abnormal_tail_morphology0.99294865
73MP0002928_abnormal_bile_duct0.98406605
74MP0000343_altered_response_to0.96282435
75MP0000026_abnormal_inner_ear0.96114303
76MP0002734_abnormal_mechanical_nocicepti0.95589275
77MP0004084_abnormal_cardiac_muscle0.94712181
78MP0002638_abnormal_pupillary_reflex0.94379939
79MP0000613_abnormal_salivary_gland0.94148597
80MP0008004_abnormal_stomach_pH0.93907081
81MP0002060_abnormal_skin_morphology0.93372328
82MP0005369_muscle_phenotype0.92916208
83MP0000462_abnormal_digestive_system0.92298160
84MP0004484_altered_response_of0.92192226
85MP0000631_abnormal_neuroendocrine_gland0.92103282
86MP0003941_abnormal_skin_development0.90950866
87MP0004197_abnormal_fetal_growth/weight/0.90772922
88MP0005551_abnormal_eye_electrophysiolog0.89292684
89MP0002272_abnormal_nervous_system0.89002423
90MP0004885_abnormal_endolymph0.88049857
91MP0002234_abnormal_pharynx_morphology0.87494865
92MP0003122_maternal_imprinting0.86888495
93MP0003787_abnormal_imprinting0.86517503
94MP0004087_abnormal_muscle_fiber0.85576440
95MP0001984_abnormal_olfaction0.85190546
96MP0003195_calcinosis0.82800480
97MP0000428_abnormal_craniofacial_morphol0.82598970
98MP0003656_abnormal_erythrocyte_physiolo0.81619425
99MP0001243_abnormal_dermal_layer0.80846046
100MP0005408_hypopigmentation0.80449371
101MP0003436_decreased_susceptibility_to0.80236300
102MP0004142_abnormal_muscle_tone0.79916436
103MP0003937_abnormal_limbs/digits/tail_de0.78964182
104MP0003950_abnormal_plasma_membrane0.77299909
105MP0002106_abnormal_muscle_physiology0.77271907
106MP0005164_abnormal_response_to0.74442752
107MP0005084_abnormal_gallbladder_morpholo0.73506255
108MP0001486_abnormal_startle_reflex0.73272576
109MP0002184_abnormal_innervation0.72315604
110MP0000534_abnormal_ureter_morphology0.70324128
111MP0002752_abnormal_somatic_nervous0.68873300
112MP0004133_heterotaxia0.68787513
113MP0005391_vision/eye_phenotype0.68139924
114MP0001485_abnormal_pinna_reflex0.67354110
115MP0004233_abnormal_muscle_weight0.66798162
116MP0001286_abnormal_eye_development0.66365935
117MP0005646_abnormal_pituitary_gland0.64947117
118MP0003635_abnormal_synaptic_transmissio0.64444368
119MP0000767_abnormal_smooth_muscle0.64443095
120MP0002837_dystrophic_cardiac_calcinosis0.61878831
121MP0001970_abnormal_pain_threshold0.61873927
122MP0005367_renal/urinary_system_phenotyp0.61410540
123MP0000516_abnormal_urinary_system0.61410540
124MP0001663_abnormal_digestive_system0.60870387
125MP0002557_abnormal_social/conspecific_i0.60495242
126MP0002736_abnormal_nociception_after0.60265465
127MP0009745_abnormal_behavioral_response0.59528840
128MP0003252_abnormal_bile_duct0.59112036
129MP0005381_digestive/alimentary_phenotyp0.58022893
130MP0004145_abnormal_muscle_electrophysio0.58014562
131MP0001177_atelectasis0.57908776
132MP0001968_abnormal_touch/_nociception0.57254834
133MP0001963_abnormal_hearing_physiology0.57014556
134MP0006072_abnormal_retinal_apoptosis0.56766363
135MP0005195_abnormal_posterior_eye0.56582202
136MP0002295_abnormal_pulmonary_circulatio0.56088606
137MP0002876_abnormal_thyroid_physiology0.55691007
138MP0004270_analgesia0.54467946
139MP0005248_abnormal_Harderian_gland0.54398921
140MP0003121_genomic_imprinting0.54351058
141MP0005379_endocrine/exocrine_gland_phen0.54346256
142MP0009053_abnormal_anal_canal0.54280712
143MP0002168_other_aberrant_phenotype0.54201362
144MP0001943_abnormal_respiration0.54024012
145MP0006054_spinal_hemorrhage0.52640527
146MP0005595_abnormal_vascular_smooth0.47407949
147MP0010352_gastrointestinal_tract_polyps0.45074690
148MP0004036_abnormal_muscle_relaxation0.45013999

Predicted human phenotypes

RankGene SetZ-score
1Epiphyseal dysplasia (HP:0002656)8.48568793
2Irregular epiphyses (HP:0010582)7.94789608
3Vitreoretinal degeneration (HP:0000655)6.88221719
4Hypoplastic ischia (HP:0003175)6.36352481
5Cupped ribs (HP:0000887)6.01972881
6Abnormality of the ischium (HP:0003174)5.60483185
7Abnormal tarsal ossification (HP:0008369)5.45909815
8Aplasia/Hypoplasia of the pubic bone (HP:0009104)5.44725542
9Small epiphyses (HP:0010585)5.34620434
10Flat acetabular roof (HP:0003180)5.07691861
11Flat capital femoral epiphysis (HP:0003370)4.70868713
12Neonatal short-limb short stature (HP:0008921)4.68577125
13Delayed epiphyseal ossification (HP:0002663)4.65429737
14Genu varum (HP:0002970)4.30137718
15Abnormal foot bone ossification (HP:0010675)4.05368470
16Soft skin (HP:0000977)4.02038709
17Metaphyseal cupping (HP:0003021)3.97296379
18Flattened epiphyses (HP:0003071)3.90367225
19Wrist flexion contracture (HP:0001239)3.90178318
20Aortic dissection (HP:0002647)3.89554129
21Abnormality involving the epiphyses of the lower limbs (HP:0006500)3.86390787
22Abnormality of femoral epiphyses (HP:0006499)3.86390787
23Thin ribs (HP:0000883)3.75594067
24Osteoarthritis (HP:0002758)3.72676864
25Abnormality of the vertebral endplates (HP:0005106)3.66632385
26Absent epiphyses (HP:0010577)3.63736030
27Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)3.63736030
28Arthropathy (HP:0003040)3.57083314
29Mild short stature (HP:0003502)3.48265691
30Abnormality of the epiphysis of the femoral head (HP:0010574)3.40395685
31Metaphyseal irregularity (HP:0003025)3.38799817
32Short femoral neck (HP:0100864)3.34193324
33Hip contracture (HP:0003273)3.32237557
34Coxa vara (HP:0002812)3.26147940
35Round ear (HP:0100830)3.25002026
36Increased corneal curvature (HP:0100692)3.24461983
37Keratoconus (HP:0000563)3.24461983
38Metaphyseal dysplasia (HP:0100255)3.22590777
39Cervical subluxation (HP:0003308)3.21091835
40Action tremor (HP:0002345)3.17848015
41Limited hip movement (HP:0008800)3.17183633
42Protuberant abdomen (HP:0001538)3.16554002
43Abnormality of the femoral head (HP:0003368)3.12056004
44Irregular vertebral endplates (HP:0003301)3.11629445
45Abnormality of the pubic bones (HP:0003172)3.09303420
46Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)3.05417884
47Papilledema (HP:0001085)3.02009889
48Waddling gait (HP:0002515)2.99724753
49Abnormality of carpal bone ossification (HP:0006257)2.96048825
50Abnormal vertebral ossification (HP:0100569)2.95405678
51Distal arthrogryposis (HP:0005684)2.95283027
52Platyspondyly (HP:0000926)2.90571761
53Ulnar deviation of the wrist (HP:0003049)2.88180025
54Ovoid vertebral bodies (HP:0003300)2.79652746
55Long clavicles (HP:0000890)2.74464024
56Hyperventilation (HP:0002883)2.73869260
57Tubular atrophy (HP:0000092)2.73791990
58Beaking of vertebral bodies (HP:0004568)2.73422585
59Thoracolumbar scoliosis (HP:0002944)2.73290881
60Protrusio acetabuli (HP:0003179)2.71151474
61Spondylolisthesis (HP:0003302)2.71111805
62Nephronophthisis (HP:0000090)2.66755654
63Absent frontal sinuses (HP:0002688)2.65752015
64Anterior segment dysgenesis (HP:0007700)2.65663975
65Medial flaring of the eyebrow (HP:0010747)2.65111429
66Enlarged epiphyses (HP:0010580)2.64755594
67Abnormality of midbrain morphology (HP:0002418)2.62569800
68Molar tooth sign on MRI (HP:0002419)2.62569800
69Abnormality of the phalanges of the 2nd finger (HP:0009541)2.61541408
70Ulnar claw (HP:0001178)2.60531212
71Tubulointerstitial fibrosis (HP:0005576)2.59568389
72Premature rupture of membranes (HP:0001788)2.59269637
73Fetal akinesia sequence (HP:0001989)2.58331333
74Pancreatic fibrosis (HP:0100732)2.57190506
75Aplasia of the musculature (HP:0100854)2.54274676
76Rib fusion (HP:0000902)2.52760697
77Limited elbow extension (HP:0001377)2.52307529
78Lumbar hyperlordosis (HP:0002938)2.52068837
79Abnormality of the proximal phalanges of the hand (HP:0009834)2.51320603
80Vertebral clefting (HP:0008428)2.51134141
81Exostoses (HP:0100777)2.50418667
82Barrel-shaped chest (HP:0001552)2.47537733
83Stillbirth (HP:0003826)2.46301510
84True hermaphroditism (HP:0010459)2.44275974
85Gait imbalance (HP:0002141)2.42990855
86Infantile muscular hypotonia (HP:0008947)2.38583022
87Abnormal hand bone ossification (HP:0010660)2.36993879
88Aortic aneurysm (HP:0004942)2.36025620
89Abnormal ossification of hand bones (HP:0005921)2.33744587
90Hypoplasia of the odontoid process (HP:0003311)2.33472985
91Aplasia/hypoplasia of the femur (HP:0005613)2.33389057
92Partial duplication of the phalanx of hand (HP:0009999)2.32903489
93Aplasia/Hypoplasia of the vertebrae (HP:0008515)2.32877918
94Vertebral hypoplasia (HP:0008417)2.32877918
95Aplasia/Hypoplasia of the tongue (HP:0010295)2.32036091
96Pancreatic cysts (HP:0001737)2.32032661
97Breech presentation (HP:0001623)2.31800955
98Symphalangism affecting the phalanges of the hand (HP:0009773)2.31509581
99Spinal cord compression (HP:0002176)2.30901028
100Abnormality of the acetabulum (HP:0003170)2.30828015
101Atrophic scars (HP:0001075)2.29785822
102Congenital primary aphakia (HP:0007707)2.26423887
103Aplasia/Hypoplasia involving the pelvis (HP:0009103)2.22131519
104Mesomelia (HP:0003027)2.20766399
105Bladder diverticulum (HP:0000015)2.19943093
106Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)2.19314362
107Abnormality of the renal medulla (HP:0100957)2.18914979
108Broad metatarsal (HP:0001783)2.18489996
109Fibular hypoplasia (HP:0003038)2.17947406
110Cerebellar dysplasia (HP:0007033)2.16973284
111Type 1 muscle fiber predominance (HP:0003803)2.15674879
112Morphological abnormality of the middle ear (HP:0008609)2.14595782
113Abnormality of incisor morphology (HP:0011063)2.14585319
114Wide anterior fontanel (HP:0000260)2.14301142
115Abnormal finger flexion creases (HP:0006143)2.14093868
116Hypoplasia of the iris (HP:0007676)2.14092393
117Genu recurvatum (HP:0002816)2.13431269
118Glossoptosis (HP:0000162)2.13406712
119Muscle fiber splitting (HP:0003555)2.13172980
120Carpal bone hypoplasia (HP:0001498)2.13155129
121Type II lissencephaly (HP:0007260)2.11685583
122Genital tract atresia (HP:0001827)2.08909090
123Hyperextensible skin (HP:0000974)2.08397481
124Absent/shortened dynein arms (HP:0200106)2.05311889
125Dynein arm defect of respiratory motile cilia (HP:0012255)2.05311889
126Striae distensae (HP:0001065)2.02911653
127Abnormal drinking behavior (HP:0030082)2.02047590
128Polydipsia (HP:0001959)2.02047590
129Abnormality of the lumbar spine (HP:0100712)2.01933816
130Vaginal atresia (HP:0000148)2.01552130
131Abnormality of the vitreous humor (HP:0004327)2.01443565
132Bulbous nose (HP:0000414)2.00256645
133Joint stiffness (HP:0001387)1.99181251
134Cutaneous syndactyly (HP:0012725)1.97992621
135Cutaneous finger syndactyly (HP:0010554)1.97627112
136Peritonitis (HP:0002586)1.97163389
137Abnormality of the calcaneus (HP:0008364)1.96754122
138Calcaneovalgus deformity (HP:0001848)1.96356403
139Micromelia (HP:0002983)1.96107580
140Narrow nasal bridge (HP:0000446)1.95429385
141Abnormality of the odontoid process (HP:0003310)1.95196417
142Nephrogenic diabetes insipidus (HP:0009806)1.94960669
143Cerebral aneurysm (HP:0004944)1.94558326
144Tibial bowing (HP:0002982)1.94461981
145Absent phalangeal crease (HP:0006109)1.91921524
146Broad phalanx (HP:0006009)1.91554861
147Hypoplastic ilia (HP:0000946)1.91431913
148Hemiparesis (HP:0001269)1.90886644
149Ulnar bowing (HP:0003031)1.90712866
150Tubulointerstitial abnormality (HP:0001969)1.89998792
151Broad long bones (HP:0005622)1.89750136
152Disproportionate short-trunk short stature (HP:0003521)1.88800621
153Decreased muscle mass (HP:0003199)1.88708568
154Popliteal pterygium (HP:0009756)1.88619441
155Bile duct proliferation (HP:0001408)1.88561515
156Abnormal biliary tract physiology (HP:0012439)1.88561515
157Aplasia/Hypoplasia involving the vertebral column (HP:0008518)1.88181813
158Abnormality of the 2nd finger (HP:0004100)1.88079025
159Chronic hepatic failure (HP:0100626)1.87979556
160Abnormality of the anterior chamber (HP:0000593)1.86002715
161Mildly elevated creatine phosphokinase (HP:0008180)1.85440193
162Ectopia lentis (HP:0001083)1.85428710
163Overgrowth (HP:0001548)1.84666754
164Short foot (HP:0001773)1.81596936
165Aplasia/Hypoplasia of the lens (HP:0008063)1.81494889
166Anomalous pulmonary venous return (HP:0010772)1.81429338
167Mitral valve prolapse (HP:0001634)1.80850475
168Bifid tongue (HP:0010297)1.80660220
169Rhizomelia (HP:0008905)1.79539071
170Radial bowing (HP:0002986)1.78913082
171Abnormality of dentin (HP:0010299)1.78126031
172Aplasia/Hypoplasia of the scapulae (HP:0006713)1.77949454
173Hypoplastic scapulae (HP:0000882)1.77949454
174Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.77544432
175Abnormality of the frontal sinuses (HP:0002687)1.74753228

Predicted kinase interactions (KEA)

RankGene SetZ-score
1DDR26.82978884
2MAP3K36.14582133
3STK38L4.39690728
4NME14.02469900
5CASK3.83384965
6AKT33.67865403
7MUSK3.45897351
8STK243.27088159
9FGFR23.05516435
10FRK3.00946233
11MAP3K42.98760967
12MOS2.85397264
13TRIB32.45297630
14PRKG22.36262068
15DYRK32.29253432
16PIM22.18360732
17PRKD32.16580660
18STK162.07989282
19ERBB32.05313190
20TNIK2.00416135
21NTRK31.98177210
22PINK11.93505073
23BMPR1B1.90887100
24LATS11.87978352
25MARK11.85509544
26PIK3CG1.81530036
27MAP4K21.79798120
28MST41.74973150
29SGK21.64162221
30TNK21.61745382
31MAPK131.58008258
32PLK21.55991966
33NTRK21.52930227
34SIK11.46182238
35EPHA41.44660629
36STK31.38205868
37MAPK151.37432067
38TRPM71.35499605
39EPHB21.33910766
40SGK2231.27499119
41SGK4941.27499119
42GRK11.27498912
43TIE11.22841454
44ROCK11.22561681
45EPHB11.21950240
46MAP2K71.18731251
47MAPK121.18692622
48ACVR1B1.17855842
49MKNK21.16492710
50LIMK11.11731821
51PDK21.11679385
52TAOK11.10412108
53ICK1.09800454
54TYK21.09539685
55CSNK1G11.09528426
56DYRK1A1.07349332
57PIK3CA1.05664085
58TYRO31.05421237
59SGK31.03188384
60NUAK11.02619780
61MAP3K61.01094105
62NME21.01024785
63INSRR1.00654368
64MAPK70.98952326
65MAP2K40.96076320
66PKN10.94842750
67TAOK30.92854452
68EPHA30.91693462
69TTN0.90134051
70NEK60.89010545
71LATS20.87439641
72DYRK20.83678450
73MINK10.81583952
74EIF2AK30.81361770
75MAP3K70.79078432
76PKN20.78235452
77PTK20.77697463
78PAK20.76703547
79CSNK1G20.76588506
80WNK40.76426290
81MAP2K10.76311285
82GSK3A0.73079662
83PNCK0.72603474
84UHMK10.72329142
85DMPK0.72049311
86FGFR40.71906509
87CAMKK20.71622789
88EIF2AK10.70331388
89MARK20.69210981
90TESK10.68884424
91WNK30.68028369
92PHKG10.67509380
93PHKG20.67509380
94DAPK20.67083312
95MAPK40.66913936
96ADRBK10.66856777
97PRKCG0.66158883
98WNK10.65865537
99ADRBK20.65621835
100CDK140.64224532
101MKNK10.63982252
102TGFBR10.63337618
103PTK2B0.61509977
104PRKCE0.61192761
105MET0.60714338
106ERN10.60323200
107PAK40.59283524
108PRKD20.57698977
109FGFR10.57555899
110FGFR30.56826359
111FER0.56025774
112SGK10.55234917
113RIPK10.54805683
114LRRK20.54671447
115CSNK1G30.54624086
116CDK60.54080784
117CSNK1A1L0.53886485
118TGFBR20.53789018
119MST1R0.51313277
120TLK10.50259183
121CSNK1A10.50129596
122TAOK20.49645398
123MTOR0.49044129
124CDK150.48695073
125PRKACA0.47861919
126STK110.47694726
127CDK180.47539228
128PTK60.46193054
129KIT0.45980684
130SIK20.45567412
131PRKCH0.45351693
132MAP3K50.45150457
133RET0.45012713
134ILK0.44793245
135ROCK20.44233830
136OXSR10.44158346
137CDK11A0.43193342
138PDGFRA0.42371930
139CAMK2A0.41876632
140PAK30.40402926
141EPHA20.40259699
142OBSCN0.38829539
143ABL10.38695874
144JAK10.38008158
145CAMK10.37982063
146MAP2K30.37843442
147TAF10.37708961
148PBK0.37294266
149NLK0.36628202
150DYRK1B0.34996942
151BMX0.34555554
152PIM10.32427867
153NEK90.32334917
154MAP3K100.31241002
155INSR0.30160801
156ABL20.28559535
157PRKG10.24727690
158KSR10.23198003
159ERBB40.23159932
160CAMKK10.20937058
161PDGFRB0.20108667
162MAP3K110.19641437
163MAPK10.18843246
164BRSK20.18815127
165PLK30.18370185
166STK390.18023740
167PRKCD0.17868994

Predicted pathways (KEGG)

RankGene SetZ-score
1Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005326.91497015
2ECM-receptor interaction_Homo sapiens_hsa045126.10715313
3Protein digestion and absorption_Homo sapiens_hsa049745.39447943
4Focal adhesion_Homo sapiens_hsa045102.83353734
5Sulfur metabolism_Homo sapiens_hsa009202.38567833
6Nicotine addiction_Homo sapiens_hsa050332.15065380
7TGF-beta signaling pathway_Homo sapiens_hsa043502.13107459
8Malaria_Homo sapiens_hsa051442.02166968
9Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005202.00299766
10Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.98029778
11Circadian rhythm_Homo sapiens_hsa047101.97893257
12Sphingolipid metabolism_Homo sapiens_hsa006001.95257156
13Phototransduction_Homo sapiens_hsa047441.88396427
14Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.86692351
15Dilated cardiomyopathy_Homo sapiens_hsa054141.81134191
16PI3K-Akt signaling pathway_Homo sapiens_hsa041511.75949485
17Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.74579258
18Proteoglycans in cancer_Homo sapiens_hsa052051.73358094
19Pentose and glucuronate interconversions_Homo sapiens_hsa000401.73004275
20Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.71365446
21Linoleic acid metabolism_Homo sapiens_hsa005911.70108311
22Starch and sucrose metabolism_Homo sapiens_hsa005001.66896951
23Glutamatergic synapse_Homo sapiens_hsa047241.62995989
24Circadian entrainment_Homo sapiens_hsa047131.57320734
25Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.55390904
26Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.50306691
27Steroid biosynthesis_Homo sapiens_hsa001001.49924652
28alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.43386636
29Butanoate metabolism_Homo sapiens_hsa006501.42365630
30Insulin secretion_Homo sapiens_hsa049111.42334213
31Ether lipid metabolism_Homo sapiens_hsa005651.40750044
32ABC transporters_Homo sapiens_hsa020101.40165190
33Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.39251458
34Amphetamine addiction_Homo sapiens_hsa050311.34762845
35Renin secretion_Homo sapiens_hsa049241.34667534
36Hippo signaling pathway_Homo sapiens_hsa043901.31842757
37Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.28166781
38Arginine and proline metabolism_Homo sapiens_hsa003301.28157853
39Taste transduction_Homo sapiens_hsa047421.26899053
40Dopaminergic synapse_Homo sapiens_hsa047281.25368839
41Hedgehog signaling pathway_Homo sapiens_hsa043401.24036128
42Selenocompound metabolism_Homo sapiens_hsa004501.19234871
43Protein export_Homo sapiens_hsa030601.18773760
44Morphine addiction_Homo sapiens_hsa050321.18339576
45Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.16178445
46Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.13239924
47Basal cell carcinoma_Homo sapiens_hsa052171.10971016
48Tryptophan metabolism_Homo sapiens_hsa003801.09082199
49Other glycan degradation_Homo sapiens_hsa005111.07664847
50Primary bile acid biosynthesis_Homo sapiens_hsa001201.07162548
51AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.07046894
52GABAergic synapse_Homo sapiens_hsa047271.06670222
53Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.05912674
54Peroxisome_Homo sapiens_hsa041461.04925681
55Dorso-ventral axis formation_Homo sapiens_hsa043201.04713185
56Propanoate metabolism_Homo sapiens_hsa006401.03121405
57Gastric acid secretion_Homo sapiens_hsa049711.01841874
58Salivary secretion_Homo sapiens_hsa049701.01478878
59Bladder cancer_Homo sapiens_hsa052191.01420025
60Serotonergic synapse_Homo sapiens_hsa047261.00763110
61Nitrogen metabolism_Homo sapiens_hsa009101.00141336
62Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.98837199
63Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.97786345
64Vascular smooth muscle contraction_Homo sapiens_hsa042700.96971705
65Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.95667941
66Amoebiasis_Homo sapiens_hsa051460.93514085
67Phagosome_Homo sapiens_hsa041450.91466874
68Aldosterone synthesis and secretion_Homo sapiens_hsa049250.90117657
69Cholinergic synapse_Homo sapiens_hsa047250.88977271
70Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.88271086
71Calcium signaling pathway_Homo sapiens_hsa040200.87031492
72Fat digestion and absorption_Homo sapiens_hsa049750.86408152
73Vibrio cholerae infection_Homo sapiens_hsa051100.86312644
74Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.85536495
75Adherens junction_Homo sapiens_hsa045200.85381043
76Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.80841774
77Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.80699870
78Ras signaling pathway_Homo sapiens_hsa040140.77918953
79cAMP signaling pathway_Homo sapiens_hsa040240.77741713
80Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.77682683
81Ovarian steroidogenesis_Homo sapiens_hsa049130.75326382
82Histidine metabolism_Homo sapiens_hsa003400.73190547
83Glycosaminoglycan degradation_Homo sapiens_hsa005310.72848466
84Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.71247737
85Pancreatic secretion_Homo sapiens_hsa049720.71053294
86MicroRNAs in cancer_Homo sapiens_hsa052060.70657906
87Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.69148814
88Thyroid hormone synthesis_Homo sapiens_hsa049180.67363194
89Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.66894488
90Glycerolipid metabolism_Homo sapiens_hsa005610.64826862
91HIF-1 signaling pathway_Homo sapiens_hsa040660.64729058
92Regulation of autophagy_Homo sapiens_hsa041400.63005651
93Olfactory transduction_Homo sapiens_hsa047400.61751426
94Glycerophospholipid metabolism_Homo sapiens_hsa005640.61008326
95Regulation of actin cytoskeleton_Homo sapiens_hsa048100.59881219
96Wnt signaling pathway_Homo sapiens_hsa043100.56908276
97Galactose metabolism_Homo sapiens_hsa000520.56278583
98Lysine degradation_Homo sapiens_hsa003100.55113945
99Pertussis_Homo sapiens_hsa051330.54270934
100Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.53536889
101Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.53494330
102cGMP-PKG signaling pathway_Homo sapiens_hsa040220.51401196
103Chemical carcinogenesis_Homo sapiens_hsa052040.49752457
104Renin-angiotensin system_Homo sapiens_hsa046140.49104725
105Arachidonic acid metabolism_Homo sapiens_hsa005900.48583430
106Longevity regulating pathway - mammal_Homo sapiens_hsa042110.47745334
107Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.46316225
108Caffeine metabolism_Homo sapiens_hsa002320.45252403
109Prostate cancer_Homo sapiens_hsa052150.45203389
110N-Glycan biosynthesis_Homo sapiens_hsa005100.45032443
111African trypanosomiasis_Homo sapiens_hsa051430.44351929
112Fatty acid metabolism_Homo sapiens_hsa012120.44010184
113Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.42517754
114Tight junction_Homo sapiens_hsa045300.42467571
115Melanoma_Homo sapiens_hsa052180.42123050
116Oxytocin signaling pathway_Homo sapiens_hsa049210.41621798
117Melanogenesis_Homo sapiens_hsa049160.41287323
118Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.40728257
119Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.38573238
120Gap junction_Homo sapiens_hsa045400.37777783
121Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.37709832
122Platelet activation_Homo sapiens_hsa046110.36502325
123Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.33734587
124Small cell lung cancer_Homo sapiens_hsa052220.33213783
125Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.32902872
126Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.32821522
127Axon guidance_Homo sapiens_hsa043600.32512421
128Chronic myeloid leukemia_Homo sapiens_hsa052200.32472094
129Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.32441021
130Glioma_Homo sapiens_hsa052140.31060731
131Vitamin digestion and absorption_Homo sapiens_hsa049770.31051805
132Viral myocarditis_Homo sapiens_hsa054160.31046514
133Rap1 signaling pathway_Homo sapiens_hsa040150.30890863
134Renal cell carcinoma_Homo sapiens_hsa052110.30579840
135HTLV-I infection_Homo sapiens_hsa051660.28654054
136FoxO signaling pathway_Homo sapiens_hsa040680.28578667
137SNARE interactions in vesicular transport_Homo sapiens_hsa041300.27642278
138Pathways in cancer_Homo sapiens_hsa052000.27034256
139Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.26714624
140Insulin resistance_Homo sapiens_hsa049310.26581390
141Leukocyte transendothelial migration_Homo sapiens_hsa046700.24165722
142Thyroid hormone signaling pathway_Homo sapiens_hsa049190.24107981
143Apoptosis_Homo sapiens_hsa042100.23238134
144Bile secretion_Homo sapiens_hsa049760.23059042
145Pancreatic cancer_Homo sapiens_hsa052120.22941540
146Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.21482365
147Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.21469897
148MAPK signaling pathway_Homo sapiens_hsa040100.19899095
149mTOR signaling pathway_Homo sapiens_hsa041500.19577854
150Long-term depression_Homo sapiens_hsa047300.19352816
151Central carbon metabolism in cancer_Homo sapiens_hsa052300.18919046
152Cocaine addiction_Homo sapiens_hsa050300.18607454
153Complement and coagulation cascades_Homo sapiens_hsa046100.18537103
154Hepatitis B_Homo sapiens_hsa051610.17536861
155Glucagon signaling pathway_Homo sapiens_hsa049220.17205695
156Cardiac muscle contraction_Homo sapiens_hsa042600.16706151

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